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Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
**Still some additional cleaning from time to time**
Sorry for the inconvenience.
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Maltodextrin binding protein
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The Maltodextrin binding protein undergoes a hinge movement between its closed (left image, blue cartoon,
1anf)
and open form (left image, red cartoon, 1omp).
Application of a normal mode perturbation of dq=180 in the direction of mode 7 transforms the closed
form into the open form (right image, animated VanDerWaals spheres). Using this perturbed template in molecular replacement (AMoRe) it becomes
possible to solve the structure of the open form. The final R-free after CNS refinement of
the perturbed model is 45.3, compared to 51.1 when using the closed form as a template
(see also Molmovdb
for an analysis of this protein's movement).
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click to enlarge (18.0MB)
If you find results from this site helpful for your research, please cite one of our papers:
elNémo
is maintained by Yves-Henri Sanejouand.
It was developed
by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.
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