 |
| home | start a new run | job status | references&downloads | examples | help |
Should you encounter any unexpected behaviour, |
*** a somamer ***elNémo ID: 251228183036573973Job options:ID = 251228183036573973 JOBID = a somamer USERID = KS PRIVAT = 0 NMODES = 5 DQMIN = -100 DQMAX = 100 DQSTEP = 20 DOGRAPHS = on DOPROJMODS = 0 DORMSD = 0 NRBL = 0 CUTOFF = 0 CAONLY = 0 Input data for this run:HEADER a somamer HEADER HORMONE/DNA 26-OCT-12 4HQU TITLE CRYSTAL STRUCTURE OF HUMAN PDGF-BB IN COMPLEX WITH A MODIFIED TITLE 2 NUCLEOTIDE APTAMER (SOMAMER SL5) COMPND MOL_ID: 1; COMPND 2 MOLECULE: PLATELET-DERIVED GROWTH FACTOR SUBUNIT B; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: PDGF-BB, UNP RESIDUES 82-109; COMPND 5 SYNONYM: PDGF SUBUNIT B, PDGF-2, PLATELET-DERIVED GROWTH FACTOR B COMPND 6 CHAIN, PLATELET-DERIVED GROWTH FACTOR BETA POLYPEPTIDE, PROTO- COMPND 7 ONCOGENE C-SIS; COMPND 8 ENGINEERED: YES; COMPND 9 MOL_ID: 2; COMPND 10 MOLECULE: SOMAMER SL5; COMPND 11 CHAIN: C; COMPND 12 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: PDGFB, PDGF2, SIS; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 MOL_ID: 2; SOURCE 9 SYNTHETIC: YES; SOURCE 10 OTHER_DETAILS: SYNTHESIZED OLIGONUCLEOTIDE KEYWDS GROWTH FACTOR, SELEX, APTAMER, 5-MODIFIED DEOXYURIDINE, HORMONE-DNA KEYWDS 2 COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR D.R.DAVIES,T.E.EDWARDS,N.JANJIC,A.D.GELINAS,C.ZHANG,T.C.JARVIS REVDAT 2 19-DEC-12 4HQU 1 JRNL REVDAT 1 21-NOV-12 4HQU 0 JRNL AUTH D.R.DAVIES,A.D.GELINAS,C.ZHANG,J.C.ROHLOFF,J.D.CARTER, JRNL AUTH 2 D.O'CONNELL,S.M.WAUGH,S.K.WOLK,W.S.MAYFIELD,A.B.BURGIN, JRNL AUTH 3 T.E.EDWARDS,L.J.STEWART,L.GOLD,N.JANJIC,T.C.JARVIS JRNL TITL UNIQUE MOTIFS AND HYDROPHOBIC INTERACTIONS SHAPE THE BINDING JRNL TITL 2 OF MODIFIED DNA LIGANDS TO PROTEIN TARGETS. JRNL REF PROC.NATL.ACAD.SCI.USA V. 109 19971 2012 JRNL REFN ISSN 0027-8424 JRNL PMID 23139410 JRNL DOI 10.1073/PNAS.1213933109 REMARK 2 REMARK 2 RESOLUTION. 2.20 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.6.0117 REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.20 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 19.27 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : NULL REMARK 3 NUMBER OF REFLECTIONS : 15628 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.227 REMARK 3 R VALUE (WORKING SET) : 0.225 REMARK 3 FREE R VALUE : 0.262 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.000 REMARK 3 FREE R VALUE TEST SET COUNT : 786 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.20 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.26 REMARK 3 REFLECTION IN BIN (WORKING SET) : 954 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 98.82 REMARK 3 BIN R VALUE (WORKING SET) : 0.3290 REMARK 3 BIN FREE R VALUE SET COUNT : 51 REMARK 3 BIN FREE R VALUE : 0.3530 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 738 REMARK 3 NUCLEIC ACID ATOMS : 556 REMARK 3 HETEROGEN ATOMS : 2 REMARK 3 SOLVENT ATOMS : 82 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 50.44 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 43.68 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 1.88000 REMARK 3 B22 (A**2) : 1.88000 REMARK 3 B33 (A**2) : -3.77000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.196 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.181 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.137 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 5.589 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.949 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.922 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 1381 ; 0.007 ; 0.018 REMARK 3 BOND LENGTHS OTHERS (A): NULL ; NULL ; NULL REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 1973 ; 1.882 ; 2.136 REMARK 3 BOND ANGLES OTHERS (DEGREES): NULL ; NULL ; NULL REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 96 ; 5.751 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 32 ;40.739 ;22.813 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 135 ;13.821 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 9 ;19.888 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 197 ; 0.091 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 893 ; 0.007 ; 0.021 REMARK 3 GENERAL PLANES OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.20 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN USED IF REMARK 4 REMARK 4 4HQU COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 09-NOV-12. REMARK 100 THE RCSB ID CODE IS RCSB075805. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 01-AUG-11 REMARK 200 TEMPERATURE (KELVIN) : 100.0 REMARK 200 PH : 6.50 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : APS REMARK 200 BEAMLINE : 19-ID REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.979176 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 315R REMARK 200 INTENSITY-INTEGRATION SOFTWARE : NULL REMARK 200 DATA SCALING SOFTWARE : NULL REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 15629 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.200 REMARK 200 RESOLUTION RANGE LOW (A) : 19.270 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : -3.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 96.8 REMARK 200 DATA REDUNDANCY : NULL REMARK 200 R MERGE (I) : 0.04000 REMARK 200 R SYM (I) : NULL REMARK 200 FOR THE DATA SET : 25.3300 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.20 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.26 REMARK 200 COMPLETENESS FOR SHELL (%) : 99.1 REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : 0.57800 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 FOR SHELL : 3.400 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: CHAIN A OF 3MJG REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 65.50 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.57 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: PROPLEX D8: 0.1 M MAGNESIUM ACETATE, REMARK 280 0.1 M SODIUM CACODYLATE PH 6.5, 15% PEG 6000, VAPOR DIFFUSION, REMARK 280 TEMPERATURE 289K, VAPOR DIFFUSION, SITTING DROP REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 41 21 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z+1/2 REMARK 290 3555 -Y+1/2,X+1/2,Z+1/4 REMARK 290 4555 Y+1/2,-X+1/2,Z+3/4 REMARK 290 5555 -X+1/2,Y+1/2,-Z+1/4 REMARK 290 6555 X+1/2,-Y+1/2,-Z+3/4 REMARK 290 7555 Y,X,-Z REMARK 290 8555 -Y,-X,-Z+1/2 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 83.50500 REMARK 290 SMTRY1 3 0.000000 -1.000000 0.000000 29.85500 REMARK 290 SMTRY2 3 1.000000 0.000000 0.000000 29.85500 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 41.75250 REMARK 290 SMTRY1 4 0.000000 1.000000 0.000000 29.85500 REMARK 290 SMTRY2 4 -1.000000 0.000000 0.000000 29.85500 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 125.25750 REMARK 290 SMTRY1 5 -1.000000 0.000000 0.000000 29.85500 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 29.85500 REMARK 290 SMTRY3 5 0.000000 0.000000 -1.000000 41.75250 REMARK 290 SMTRY1 6 1.000000 0.000000 0.000000 29.85500 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 29.85500 REMARK 290 SMTRY3 6 0.000000 0.000000 -1.000000 125.25750 REMARK 290 SMTRY1 7 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY2 7 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 8 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY2 8 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 83.50500 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 10160 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 18010 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -12.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, C REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 BIOMT1 2 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT2 2 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 SER A 1 REMARK 465 LEU A 2 REMARK 465 GLY A 3 REMARK 465 SER A 4 REMARK 465 LEU A 5 REMARK 465 THR A 6 REMARK 465 VAL A 102 REMARK 465 ALA A 103 REMARK 465 ALA A 104 REMARK 465 ALA A 105 REMARK 465 ARG A 106 REMARK 465 PRO A 107 REMARK 465 VAL A 108 REMARK 465 THR A 109 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 ILE A 7 CG1 CG2 CD1 REMARK 470 GLU A 15 CG CD OE1 OE2 REMARK 470 ARG A 32 CG CD NE CZ NH1 NH2 REMARK 470 ASN A 57 CG OD1 ND2 REMARK 470 LYS A 80 CG CD CE NZ REMARK 470 LYS A 81 CG CD CE NZ REMARK 470 PE6 C 5 C3 C4 O5 C6 C7 O8 C9 REMARK 470 PE6 C 5 C10 O11 C19 C18 O17 C16 C15 REMARK 470 PE6 C 5 O14 C13 C12 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ASN A 36 48.41 -75.87 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 MG C 102 MG REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HOH C 205 O REMARK 620 2 HOH C 206 O 179.3 REMARK 620 3 HOH C 202 O 91.0 89.7 REMARK 620 4 HOH C 204 O 91.8 88.2 90.1 REMARK 620 5 HOH C 201 O 89.4 90.0 179.5 89.6 REMARK 620 6 HOH C 203 O 87.9 92.1 89.6 179.5 90.7 REMARK 620 N 1 2 3 4 5 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 NA C 101 NA REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HOH C 216 O REMARK 620 2 HOH C 215 O 88.1 REMARK 620 3 DG C 22 O6 120.1 100.2 REMARK 620 4 DC C 10 O2 87.6 167.4 92.2 REMARK 620 5 HOH C 214 O 161.7 95.7 76.9 84.9 REMARK 620 6 DC C 10 O4' 79.8 101.6 150.8 65.9 81.9 REMARK 620 N 1 2 3 4 5 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NA C 101 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG C 102 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 3MJG RELATED DB: PDB REMARK 900 PDGF-BB BOUND TO RECEPTOR REMARK 900 RELATED ID: 4HQX RELATED DB: PDB REMARK 900 PDGF-BB IN COMPLEX WITH A MODIFIED NUCLEOTIDE APTAMER REMARK 900 (SOMAMER SL4) DBREF 4HQU A 1 109 UNP P01127 PDGFB_HUMAN 82 190 DBREF 4HQU C 1 24 PDB 4HQU 4HQU 1 24 SEQRES 1 A 109 SER LEU GLY SER LEU THR ILE ALA GLU PRO ALA MET ILE SEQRES 2 A 109 ALA GLU CYS LYS THR ARG THR GLU VAL PHE GLU ILE SER SEQRES 3 A 109 ARG ARG LEU ILE ASP ARG THR ASN ALA ASN PHE LEU VAL SEQRES 4 A 109 TRP PRO PRO CYS VAL GLU VAL GLN ARG CYS SER GLY CYS SEQRES 5 A 109 CYS ASN ASN ARG ASN VAL GLN CYS ARG PRO THR GLN VAL SEQRES 6 A 109 GLN LEU ARG PRO VAL GLN VAL ARG LYS ILE GLU ILE VAL SEQRES 7 A 109 ARG LYS LYS PRO ILE PHE LYS LYS ALA THR VAL THR LEU SEQRES 8 A 109 GLU ASP HIS LEU ALA CYS LYS CYS GLU THR VAL ALA ALA SEQRES 9 A 109 ALA ARG PRO VAL THR SEQRES 1 C 24 DUZ DUZ A2M DC PE6 DG DUZ DUZ DA DC A2M DC DG SEQRES 2 C 24 DC DG DUZ UPE 18Q DA DUZ A2M DG DC 18M MODRES 4HQU DUZ C 1 DU MODRES 4HQU DUZ C 2 DU MODRES 4HQU A2M C 3 A MODRES 4HQU DUZ C 7 DU MODRES 4HQU DUZ C 8 DU MODRES 4HQU A2M C 11 A MODRES 4HQU DUZ C 16 DU MODRES 4HQU UPE C 17 DU MODRES 4HQU 18Q C 18 DU MODRES 4HQU DUZ C 20 DU MODRES 4HQU A2M C 21 A MODRES 4HQU 18M C 24 G HET DUZ C 1 26 HET DUZ C 2 29 HET A2M C 3 23 HET PE6 C 5 5 HET DUZ C 7 29 HET DUZ C 8 29 HET A2M C 11 23 HET DUZ C 16 29 HET UPE C 17 30 HET 18Q C 18 28 HET DUZ C 20 29 HET A2M C 21 23 HET 18M C 24 28 HET NA C 101 1 HET MG C 102 1 HETNAM DUZ 5-(BENZYLCARBAMOYL)-2'-DEOXYURIDINE 5'-(DIHYDROGEN HETNAM 2 DUZ PHOSPHATE) HETNAM A2M 2'-O-METHYLADENOSINE 5'-(DIHYDROGEN PHOSPHATE) HETNAM PE6 PHOSPHORYL-HEXAETHYLENE GLYCOL HETNAM UPE 2'-DEOXY-5-[(2-PHENYLETHYL)CARBAMOYL]URIDINE 5'- HETNAM 2 UPE (DIHYDROGEN PHOSPHATE) HETNAM 18Q 2'-DEOXY-5-[(THIOPHEN-2-YLMETHYL)CARBAMOYL]URIDINE 5'- HETNAM 2 18Q (DIHYDROGEN PHOSPHATE) HETNAM 18M 2'-O-METHYLGUANOSINE 3',5'-BIS(DIHYDROGEN PHOSPHATE) HETNAM NA SODIUM ION HETNAM MG MAGNESIUM ION FORMUL 2 DUZ 6(C17 H20 N3 O9 P) FORMUL 2 A2M 3(C11 H16 N5 O7 P) FORMUL 2 PE6 C12 H27 O10 P FORMUL 2 UPE C18 H22 N3 O9 P FORMUL 2 18Q C15 H18 N3 O9 P S FORMUL 2 18M C11 H17 N5 O11 P2 FORMUL 3 NA NA 1+ FORMUL 4 MG MG 2+ FORMUL 5 HOH *82(H2 O) HELIX 1 1 SER A 26 ASP A 31 1 6 SHEET 1 A 2 LYS A 17 GLU A 24 0 SHEET 2 A 2 CYS A 43 SER A 50 -1 O VAL A 44 N PHE A 23 SHEET 1 B 3 PHE A 37 TRP A 40 0 SHEET 2 B 3 GLN A 59 VAL A 78 -1 O ARG A 73 N TRP A 40 SHEET 3 B 3 LYS A 81 GLU A 100 -1 O LEU A 91 N ARG A 68 SSBOND 1 CYS A 16 CYS A 60 1555 1555 2.06 SSBOND 2 CYS A 43 CYS A 52 1555 7555 2.22 SSBOND 3 CYS A 49 CYS A 97 1555 1555 2.04 SSBOND 4 CYS A 53 CYS A 99 1555 1555 2.07 LINK O3' DC C 4 P1 PE6 C 5 1555 1555 1.60 LINK O3' DG C 6 P DUZ C 7 1555 1555 1.60 LINK O3' DC C 10 P A2M C 11 1555 1555 1.59 LINK O3' DG C 15 P DUZ C 16 1555 1555 1.58 LINK O3' DA C 19 P DUZ C 20 1555 1555 1.60 LINK MG MG C 102 O HOH C 205 1555 1555 2.17 LINK MG MG C 102 O HOH C 206 1555 1555 2.17 LINK MG MG C 102 O HOH C 202 1555 1555 2.18 LINK MG MG C 102 O HOH C 204 1555 1555 2.18 LINK MG MG C 102 O HOH C 201 1555 1555 2.18 LINK MG MG C 102 O HOH C 203 1555 1555 2.18 LINK NA NA C 101 O HOH C 216 1555 1555 2.19 LINK NA NA C 101 O HOH C 215 1555 1555 2.25 LINK O6 DG C 22 NA NA C 101 1555 1555 2.43 LINK O2 DC C 10 NA NA C 101 1555 1555 2.44 LINK NA NA C 101 O HOH C 214 1555 1555 2.66 LINK O4' DC C 10 NA NA C 101 1555 1555 2.92 LINK O20 PE6 C 5 P DG C 6 1555 1555 1.49 CISPEP 1 TRP A 40 PRO A 41 0 0.14 SITE 1 AC1 5 DC C 10 DG C 22 HOH C 214 HOH C 215 SITE 2 AC1 5 HOH C 216 SITE 1 AC2 6 HOH C 201 HOH C 202 HOH C 203 HOH C 204 SITE 2 AC2 6 HOH C 205 HOH C 206 CRYST1 59.710 59.710 167.010 90.00 90.00 90.00 P 41 21 2 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.016748 0.000000 0.000000 0.00000 SCALE2 0.000000 0.016748 0.000000 0.00000 SCALE3 0.000000 0.000000 0.005988 0.00000 HETATM 744 N1 DUZ C 1 -14.096 -17.021 20.727 1.00 39.60 N HETATM 745 C2 DUZ C 1 -15.405 -17.277 21.196 1.00 38.89 C HETATM 746 O2 DUZ C 1 -15.929 -16.476 22.009 1.00 39.46 O HETATM 747 N3 DUZ C 1 -16.088 -18.362 20.788 1.00 36.52 N HETATM 748 C4 DUZ C 1 -15.555 -19.218 19.908 1.00 37.80 C HETATM 749 O4 DUZ C 1 -16.205 -20.216 19.536 1.00 39.85 O HETATM 750 C5 DUZ C 1 -14.182 -18.971 19.403 1.00 38.85 C HETATM 751 C6 DUZ C 1 -13.524 -17.837 19.840 1.00 39.45 C HETATM 752 C1' DUZ C 1 -13.380 -15.810 21.160 1.00 42.74 C HETATM 753 C2' DUZ C 1 -11.987 -16.024 21.764 1.00 41.97 C HETATM 754 C21 DUZ C 1 -13.485 -19.821 18.386 1.00 38.97 C HETATM 755 O22 DUZ C 1 -12.306 -19.620 18.171 1.00 39.87 O HETATM 756 N23 DUZ C 1 -14.154 -20.709 17.662 1.00 41.39 N HETATM 757 C24 DUZ C 1 -13.604 -21.552 16.603 1.00 38.91 C HETATM 758 C25 DUZ C 1 -13.819 -20.865 15.256 1.00 38.14 C HETATM 759 C26 DUZ C 1 -13.598 -21.565 14.065 1.00 39.15 C HETATM 760 C27 DUZ C 1 -13.801 -20.941 12.828 1.00 38.97 C HETATM 761 C28 DUZ C 1 -14.218 -19.612 12.764 1.00 37.28 C HETATM 762 C29 DUZ C 1 -14.448 -18.913 13.945 1.00 37.70 C HETATM 763 C3' DUZ C 1 -11.229 -14.791 21.300 1.00 43.93 C HETATM 764 O3' DUZ C 1 -11.474 -13.700 22.196 1.00 45.70 O HETATM 765 C30 DUZ C 1 -14.250 -19.536 15.181 1.00 37.65 C HETATM 766 C4' DUZ C 1 -11.898 -14.373 20.003 1.00 44.79 C HETATM 767 O4' DUZ C 1 -13.201 -14.974 20.005 1.00 41.33 O HETATM 768 C5' DUZ C 1 -11.096 -14.772 18.767 1.00 46.25 C HETATM 769 O5' DUZ C 1 -11.014 -16.197 18.685 1.00 52.16 O HETATM 770 P DUZ C 2 -10.462 -13.338 23.378 1.00 47.42 P HETATM 771 N1 DUZ C 2 -10.872 -16.377 27.930 1.00 40.98 N HETATM 772 C2 DUZ C 2 -10.878 -17.249 29.053 1.00 39.47 C HETATM 773 O2 DUZ C 2 -10.989 -16.774 30.199 1.00 38.67 O HETATM 774 N3 DUZ C 2 -10.748 -18.577 28.922 1.00 38.21 N HETATM 775 C4 DUZ C 2 -10.640 -19.124 27.714 1.00 37.88 C HETATM 776 O4 DUZ C 2 -10.531 -20.361 27.598 1.00 38.18 O HETATM 777 C5 DUZ C 2 -10.620 -18.244 26.520 1.00 38.87 C HETATM 778 C6 DUZ C 2 -10.774 -16.877 26.691 1.00 39.56 C HETATM 779 C1' DUZ C 2 -11.077 -14.939 28.127 1.00 40.49 C HETATM 780 C2' DUZ C 2 -10.003 -13.965 27.663 1.00 42.28 C HETATM 781 C21 DUZ C 2 -10.521 -18.802 25.137 1.00 40.38 C HETATM 782 O22 DUZ C 2 -10.509 -18.031 24.193 1.00 40.56 O HETATM 783 N23 DUZ C 2 -10.505 -20.120 24.956 1.00 40.34 N HETATM 784 C24 DUZ C 2 -10.481 -20.783 23.658 1.00 41.24 C HETATM 785 C25 DUZ C 2 -11.927 -20.997 23.222 1.00 41.56 C HETATM 786 C26 DUZ C 2 -12.224 -21.413 21.920 1.00 41.35 C HETATM 787 C27 DUZ C 2 -13.552 -21.613 21.531 1.00 41.79 C HETATM 788 C28 DUZ C 2 -14.599 -21.395 22.425 1.00 39.65 C HETATM 789 C29 DUZ C 2 -14.306 -20.981 23.723 1.00 40.98 C HETATM 790 C3' DUZ C 2 -10.837 -12.763 27.230 1.00 43.08 C HETATM 791 O3' DUZ C 2 -11.164 -11.942 28.358 1.00 45.76 O HETATM 792 C30 DUZ C 2 -12.980 -20.784 24.119 1.00 41.15 C HETATM 793 C4' DUZ C 2 -12.166 -13.337 26.768 1.00 42.22 C HETATM 794 O4' DUZ C 2 -12.255 -14.633 27.356 1.00 40.49 O HETATM 795 C5' DUZ C 2 -12.307 -13.426 25.252 1.00 43.15 C HETATM 796 O5' DUZ C 2 -11.146 -14.015 24.670 1.00 45.12 O HETATM 797 OP1 DUZ C 2 -10.513 -11.835 23.550 1.00 48.62 O HETATM 798 OP2 DUZ C 2 -9.170 -14.060 23.115 1.00 44.40 O HETATM 799 P A2M C 3 -10.172 -10.845 28.980 1.00 47.34 P HETATM 800 OP1 A2M C 3 -11.031 -9.960 29.849 1.00 51.03 O HETATM 801 O5' A2M C 3 -9.194 -11.723 29.889 1.00 49.24 O HETATM 802 C5' A2M C 3 -9.675 -12.293 31.106 1.00 53.07 C HETATM 803 C4' A2M C 3 -8.604 -13.210 31.683 1.00 56.76 C HETATM 804 O4' A2M C 3 -8.551 -14.450 30.956 1.00 53.76 O HETATM 805 C3' A2M C 3 -7.204 -12.609 31.605 1.00 61.48 C HETATM 806 O3' A2M C 3 -6.579 -12.944 32.854 1.00 72.48 O HETATM 807 C2' A2M C 3 -6.591 -13.347 30.418 1.00 58.41 C HETATM 808 O2' A2M C 3 -5.166 -13.335 30.392 1.00 62.22 O HETATM 809 C1' A2M C 3 -7.194 -14.735 30.588 1.00 51.90 C HETATM 810 CM' A2M C 3 -4.660 -12.212 29.662 1.00 59.71 C HETATM 811 N9 A2M C 3 -7.183 -15.603 29.387 1.00 47.15 N HETATM 812 C8 A2M C 3 -7.102 -15.208 28.101 1.00 44.78 C HETATM 813 N7 A2M C 3 -7.135 -16.274 27.262 1.00 42.97 N HETATM 814 C5 A2M C 3 -7.244 -17.382 28.017 1.00 43.03 C HETATM 815 C6 A2M C 3 -7.334 -18.840 27.776 1.00 42.91 C HETATM 816 N6 A2M C 3 -7.313 -19.323 26.519 1.00 44.46 N HETATM 817 N1 A2M C 3 -7.440 -19.675 28.840 1.00 44.44 N HETATM 818 C2 A2M C 3 -7.467 -19.197 30.102 1.00 44.31 C HETATM 819 N3 A2M C 3 -7.388 -17.879 30.392 1.00 44.64 N HETATM 820 C4 A2M C 3 -7.280 -16.937 29.416 1.00 44.15 C HETATM 821 OP2 A2M C 3 -9.353 -10.245 27.867 1.00 51.05 O ATOM 822 P DC C 4 -5.279 -12.246 33.494 1.00 80.59 P ATOM 823 OP1 DC C 4 -5.373 -12.458 34.962 1.00 77.99 O ATOM 824 OP2 DC C 4 -5.167 -10.862 32.954 1.00 77.06 O ATOM 825 O5' DC C 4 -4.097 -13.155 32.921 1.00 82.24 O ATOM 826 C5' DC C 4 -3.092 -13.742 33.777 1.00 78.13 C ATOM 827 C4' DC C 4 -3.293 -15.233 33.936 1.00 79.13 C ATOM 828 O4' DC C 4 -4.313 -15.748 33.048 1.00 75.02 O ATOM 829 C3' DC C 4 -2.073 -16.088 33.621 1.00 81.15 C ATOM 830 O3' DC C 4 -1.119 -16.087 34.685 1.00 93.35 O ATOM 831 C2' DC C 4 -2.695 -17.457 33.426 1.00 74.81 C ATOM 832 C1' DC C 4 -4.035 -17.124 32.765 1.00 69.69 C ATOM 833 N1 DC C 4 -4.024 -17.304 31.303 1.00 65.13 N ATOM 834 C2 DC C 4 -4.103 -18.603 30.787 1.00 63.76 C ATOM 835 O2 DC C 4 -4.205 -19.557 31.572 1.00 63.80 O ATOM 836 N3 DC C 4 -4.084 -18.784 29.446 1.00 61.32 N ATOM 837 C4 DC C 4 -3.976 -17.731 28.633 1.00 61.91 C ATOM 838 N4 DC C 4 -3.961 -17.959 27.318 1.00 64.43 N ATOM 839 C5 DC C 4 -3.882 -16.398 29.132 1.00 61.31 C ATOM 840 C6 DC C 4 -3.903 -16.233 30.462 1.00 63.52 C HETATM 841 O2 PE6 C 5 0.404 -14.445 33.581 1.00 96.75 O HETATM 842 P1 PE6 C 5 0.422 -15.864 34.305 1.00101.05 P HETATM 843 OP1 PE6 C 5 0.843 -16.885 33.306 1.00 96.83 O HETATM 844 OP2 PE6 C 5 1.163 -15.737 35.587 1.00101.60 O HETATM 845 O20 PE6 C 5 -1.684 -29.370 24.034 1.00 95.79 O ATOM 846 P DG C 6 -2.481 -28.136 24.263 1.00 93.91 P ATOM 847 OP1 DG C 6 -3.389 -27.999 23.095 1.00 93.57 O ATOM 848 OP2 DG C 6 -1.558 -27.023 24.617 1.00 90.57 O ATOM 849 O5' DG C 6 -3.382 -28.479 25.530 1.00 84.53 O ATOM 850 C5' DG C 6 -2.824 -29.121 26.691 1.00 78.02 C ATOM 851 C4' DG C 6 -3.573 -28.700 27.934 1.00 73.65 C ATOM 852 O4' DG C 6 -3.512 -27.262 28.093 1.00 71.56 O ATOM 853 C3' DG C 6 -5.057 -29.069 27.964 1.00 71.38 C ATOM 854 O3' DG C 6 -5.358 -29.563 29.273 1.00 72.09 O ATOM 855 C2' DG C 6 -5.761 -27.757 27.656 1.00 67.94 C ATOM 856 C1' DG C 6 -4.817 -26.722 28.244 1.00 65.04 C ATOM 857 N9 DG C 6 -4.838 -25.427 27.572 1.00 58.46 N ATOM 858 C8 DG C 6 -4.908 -25.201 26.218 1.00 55.73 C ATOM 859 N7 DG C 6 -4.880 -23.934 25.908 1.00 54.18 N ATOM 860 C5 DG C 6 -4.776 -23.282 27.129 1.00 52.69 C ATOM 861 C6 DG C 6 -4.711 -21.895 27.430 1.00 51.98 C ATOM 862 O6 DG C 6 -4.723 -20.936 26.650 1.00 52.95 O ATOM 863 N1 DG C 6 -4.619 -21.673 28.799 1.00 51.49 N ATOM 864 C2 DG C 6 -4.593 -22.654 29.759 1.00 51.72 C ATOM 865 N2 DG C 6 -4.506 -22.235 31.028 1.00 51.65 N ATOM 866 N3 DG C 6 -4.652 -23.951 29.493 1.00 50.92 N ATOM 867 C4 DG C 6 -4.746 -24.190 28.167 1.00 53.66 C HETATM 868 P DUZ C 7 -6.826 -29.926 29.788 1.00 71.07 P HETATM 869 N1 DUZ C 7 -8.132 -24.433 30.253 1.00 50.24 N HETATM 870 C2 DUZ C 7 -7.984 -23.028 30.132 1.00 48.83 C HETATM 871 O2 DUZ C 7 -7.819 -22.317 31.152 1.00 47.85 O HETATM 872 N3 DUZ C 7 -8.025 -22.435 28.930 1.00 47.69 N HETATM 873 C4 DUZ C 7 -8.196 -23.142 27.802 1.00 50.37 C HETATM 874 O4 DUZ C 7 -8.222 -22.532 26.715 1.00 50.93 O HETATM 875 C5 DUZ C 7 -8.353 -24.624 27.891 1.00 48.89 C HETATM 876 C6 DUZ C 7 -8.303 -25.185 29.160 1.00 49.83 C HETATM 877 C1' DUZ C 7 -8.062 -25.077 31.573 1.00 57.14 C HETATM 878 C2' DUZ C 7 -9.166 -26.089 31.872 1.00 60.69 C HETATM 879 C21 DUZ C 7 -8.550 -25.613 26.772 1.00 51.72 C HETATM 880 O22 DUZ C 7 -8.656 -26.776 27.115 1.00 58.98 O HETATM 881 N23 DUZ C 7 -8.585 -25.438 25.459 1.00 51.22 N HETATM 882 C24 DUZ C 7 -8.576 -24.407 24.447 1.00 51.43 C HETATM 883 C25 DUZ C 7 -9.802 -24.882 23.693 1.00 54.43 C HETATM 884 C26 DUZ C 7 -11.024 -24.225 23.847 1.00 54.54 C HETATM 885 C27 DUZ C 7 -12.163 -24.674 23.180 1.00 54.58 C HETATM 886 C28 DUZ C 7 -12.085 -25.804 22.369 1.00 58.08 C HETATM 887 C29 DUZ C 7 -10.871 -26.483 22.228 1.00 59.50 C HETATM 888 C3' DUZ C 7 -8.486 -27.229 32.619 1.00 63.10 C HETATM 889 O3' DUZ C 7 -8.764 -27.212 34.032 1.00 66.13 O HETATM 890 C30 DUZ C 7 -9.733 -26.027 22.895 1.00 55.31 C HETATM 891 C4' DUZ C 7 -6.993 -27.007 32.417 1.00 64.22 C HETATM 892 O4' DUZ C 7 -6.827 -25.796 31.670 1.00 60.30 O HETATM 893 C5' DUZ C 7 -6.349 -28.176 31.686 1.00 64.87 C HETATM 894 O5' DUZ C 7 -7.193 -28.596 30.612 1.00 71.05 O HETATM 895 OP1 DUZ C 7 -7.741 -30.080 28.597 1.00 69.37 O HETATM 896 OP2 DUZ C 7 -6.686 -31.042 30.793 1.00 74.45 O HETATM 897 P DUZ C 8 -10.147 -27.741 34.678 1.00 68.98 P HETATM 898 N1 DUZ C 8 -10.796 -22.181 34.393 1.00 43.49 N HETATM 899 C2 DUZ C 8 -10.405 -20.836 34.235 1.00 43.70 C HETATM 900 O2 DUZ C 8 -10.134 -20.181 35.264 1.00 44.44 O HETATM 901 N3 DUZ C 8 -10.324 -20.259 33.022 1.00 42.24 N HETATM 902 C4 DUZ C 8 -10.611 -20.955 31.917 1.00 40.91 C HETATM 903 O4 DUZ C 8 -10.531 -20.401 30.795 1.00 41.67 O HETATM 904 C5 DUZ C 8 -11.016 -22.378 32.063 1.00 39.11 C HETATM 905 C6 DUZ C 8 -11.094 -22.931 33.330 1.00 40.24 C HETATM 906 C1' DUZ C 8 -10.847 -22.721 35.753 1.00 43.19 C HETATM 907 C2' DUZ C 8 -12.131 -23.467 36.081 1.00 42.98 C HETATM 908 C21 DUZ C 8 -11.371 -23.245 30.902 1.00 38.81 C HETATM 909 O22 DUZ C 8 -11.651 -24.412 31.131 1.00 40.13 O HETATM 910 N23 DUZ C 8 -11.401 -22.748 29.669 1.00 37.49 N HETATM 911 C24 DUZ C 8 -11.768 -23.471 28.458 1.00 35.55 C HETATM 912 C25 DUZ C 8 -13.272 -23.331 28.299 1.00 32.78 C HETATM 913 C26 DUZ C 8 -14.125 -24.329 28.774 1.00 33.50 C HETATM 914 C27 DUZ C 8 -15.513 -24.199 28.633 1.00 32.38 C HETATM 915 C28 DUZ C 8 -16.045 -23.058 28.021 1.00 31.54 C HETATM 916 C29 DUZ C 8 -15.190 -22.064 27.544 1.00 31.81 C HETATM 917 C3' DUZ C 8 -11.675 -24.427 37.160 1.00 45.04 C HETATM 918 O3' DUZ C 8 -11.884 -23.769 38.405 1.00 45.37 O HETATM 919 C30 DUZ C 8 -13.810 -22.196 27.694 1.00 31.87 C HETATM 920 C4' DUZ C 8 -10.168 -24.573 36.979 1.00 46.76 C HETATM 921 O4' DUZ C 8 -9.801 -23.669 35.938 1.00 44.21 O HETATM 922 C5' DUZ C 8 -9.743 -25.980 36.597 1.00 51.40 C HETATM 923 O5' DUZ C 8 -10.588 -26.457 35.550 1.00 59.64 O HETATM 924 OP1 DUZ C 8 -9.831 -28.855 35.647 1.00 68.66 O HETATM 925 OP2 DUZ C 8 -11.199 -27.988 33.613 1.00 62.23 O ATOM 926 P DA C 9 -12.201 -24.638 39.701 1.00 43.07 P ATOM 927 OP1 DA C 9 -12.101 -23.767 40.891 1.00 44.78 O ATOM 928 OP2 DA C 9 -11.412 -25.888 39.614 1.00 42.44 O ATOM 929 O5' DA C 9 -13.729 -25.002 39.459 1.00 40.69 O ATOM 930 C5' DA C 9 -14.782 -24.087 39.790 1.00 38.28 C ATOM 931 C4' DA C 9 -16.091 -24.841 39.848 1.00 37.88 C ATOM 932 O4' DA C 9 -16.616 -25.023 38.511 1.00 37.86 O ATOM 933 C3' DA C 9 -15.995 -26.246 40.437 1.00 38.94 C ATOM 934 O3' DA C 9 -17.226 -26.488 41.121 1.00 39.52 O ATOM 935 C2' DA C 9 -15.799 -27.122 39.209 1.00 36.48 C ATOM 936 C1' DA C 9 -16.645 -26.405 38.163 1.00 36.17 C ATOM 937 N9 DA C 9 -16.194 -26.516 36.774 1.00 35.93 N ATOM 938 C8 DA C 9 -14.934 -26.271 36.287 1.00 35.24 C ATOM 939 N7 DA C 9 -14.839 -26.390 34.985 1.00 37.69 N ATOM 940 C5 DA C 9 -16.129 -26.714 34.584 1.00 35.00 C ATOM 941 C6 DA C 9 -16.692 -26.967 33.319 1.00 33.61 C ATOM 942 N6 DA C 9 -15.997 -26.939 32.180 1.00 33.16 N ATOM 943 N1 DA C 9 -18.010 -27.263 33.266 1.00 34.89 N ATOM 944 C2 DA C 9 -18.707 -27.288 34.410 1.00 33.85 C ATOM 945 N3 DA C 9 -18.292 -27.063 35.656 1.00 33.60 N ATOM 946 C4 DA C 9 -16.976 -26.785 35.675 1.00 34.20 C ATOM 947 P DC C 10 -17.351 -27.626 42.217 1.00 42.77 P ATOM 948 OP1 DC C 10 -18.609 -27.339 42.950 1.00 44.49 O ATOM 949 OP2 DC C 10 -16.061 -27.742 42.946 1.00 43.85 O ATOM 950 O5' DC C 10 -17.513 -28.945 41.349 1.00 39.87 O ATOM 951 C5' DC C 10 -18.743 -29.225 40.663 1.00 40.69 C ATOM 952 C4' DC C 10 -18.595 -30.502 39.871 1.00 38.48 C ATOM 953 O4' DC C 10 -18.080 -30.204 38.551 1.00 38.81 O ATOM 954 C3' DC C 10 -17.627 -31.519 40.479 1.00 39.53 C ATOM 955 O3' DC C 10 -18.239 -32.812 40.422 1.00 40.01 O ATOM 956 C2' DC C 10 -16.408 -31.448 39.571 1.00 39.04 C ATOM 957 C1' DC C 10 -17.064 -31.136 38.243 1.00 39.22 C ATOM 958 N1 DC C 10 -16.225 -30.574 37.164 1.00 39.48 N ATOM 959 C2 DC C 10 -16.761 -30.510 35.873 1.00 38.70 C ATOM 960 O2 DC C 10 -17.929 -30.885 35.689 1.00 39.03 O ATOM 961 N3 DC C 10 -16.000 -30.028 34.864 1.00 38.64 N ATOM 962 C4 DC C 10 -14.749 -29.628 35.104 1.00 38.88 C ATOM 963 N4 DC C 10 -14.039 -29.157 34.077 1.00 37.72 N ATOM 964 C5 DC C 10 -14.173 -29.694 36.407 1.00 38.17 C ATOM 965 C6 DC C 10 -14.939 -30.170 37.398 1.00 40.23 C HETATM 966 P A2M C 11 -18.117 -33.842 41.632 1.00 39.08 P HETATM 967 OP1 A2M C 11 -18.825 -35.107 41.192 1.00 37.57 O HETATM 968 O5' A2M C 11 -16.546 -34.163 41.648 1.00 40.25 O HETATM 969 C5' A2M C 11 -15.713 -33.719 42.720 1.00 44.02 C HETATM 970 C4' A2M C 11 -14.973 -34.890 43.364 1.00 48.78 C HETATM 971 O4' A2M C 11 -15.888 -35.657 44.145 1.00 46.50 O HETATM 972 C3' A2M C 11 -14.287 -35.863 42.396 1.00 50.24 C HETATM 973 O3' A2M C 11 -12.909 -35.519 42.176 1.00 52.76 O HETATM 974 C2' A2M C 11 -14.376 -37.202 43.099 1.00 50.40 C HETATM 975 O2' A2M C 11 -13.174 -37.459 43.828 1.00 54.60 O HETATM 976 C1' A2M C 11 -15.490 -37.028 44.118 1.00 48.49 C HETATM 977 CM' A2M C 11 -12.568 -38.719 43.526 1.00 54.91 C HETATM 978 N9 A2M C 11 -16.614 -37.912 43.747 1.00 48.49 N HETATM 979 C8 A2M C 11 -17.589 -37.630 42.866 1.00 48.10 C HETATM 980 N7 A2M C 11 -18.454 -38.667 42.764 1.00 48.77 N HETATM 981 C5 A2M C 11 -18.040 -39.634 43.594 1.00 47.55 C HETATM 982 C6 A2M C 11 -18.505 -40.988 43.973 1.00 47.31 C HETATM 983 N6 A2M C 11 -19.613 -41.540 43.423 1.00 44.03 N HETATM 984 N1 A2M C 11 -17.770 -41.650 44.892 1.00 47.98 N HETATM 985 C2 A2M C 11 -16.656 -41.135 45.453 1.00 47.38 C HETATM 986 N3 A2M C 11 -16.181 -39.916 45.157 1.00 47.78 N HETATM 987 C4 A2M C 11 -16.821 -39.132 44.247 1.00 48.72 C HETATM 988 OP2 A2M C 11 -18.507 -33.110 42.889 1.00 37.83 O ATOM 989 P DC C 12 -12.382 -34.878 40.800 1.00 53.06 P ATOM 990 OP1 DC C 12 -10.947 -34.552 40.961 1.00 56.31 O ATOM 991 OP2 DC C 12 -13.327 -33.799 40.411 1.00 54.08 O ATOM 992 O5' DC C 12 -12.531 -36.077 39.766 1.00 47.89 O ATOM 993 C5' DC C 12 -11.679 -37.230 39.834 1.00 49.82 C ATOM 994 C4' DC C 12 -11.817 -38.061 38.578 1.00 49.62 C ATOM 995 O4' DC C 12 -13.163 -38.574 38.468 1.00 49.56 O ATOM 996 C3' DC C 12 -11.549 -37.328 37.266 1.00 51.77 C ATOM 997 O3' DC C 12 -10.936 -38.229 36.336 1.00 51.47 O ATOM 998 C2' DC C 12 -12.937 -36.918 36.798 1.00 48.88 C ATOM 999 C1' DC C 12 -13.815 -38.049 37.315 1.00 49.10 C ATOM 1000 N1 DC C 12 -15.176 -37.667 37.718 1.00 46.69 N ATOM 1001 C2 DC C 12 -16.260 -38.305 37.112 1.00 45.93 C ATOM 1002 O2 DC C 12 -16.043 -39.128 36.213 1.00 48.72 O ATOM 1003 N3 DC C 12 -17.517 -37.997 37.510 1.00 45.49 N ATOM 1004 C4 DC C 12 -17.708 -37.099 38.480 1.00 43.93 C ATOM 1005 N4 DC C 12 -18.964 -36.824 38.839 1.00 45.29 N ATOM 1006 C5 DC C 12 -16.619 -36.444 39.125 1.00 46.57 C ATOM 1007 C6 DC C 12 -15.381 -36.765 38.725 1.00 46.62 C ATOM 1008 P DG C 13 -10.110 -37.622 35.113 1.00 52.74 P ATOM 1009 OP1 DG C 13 -8.911 -38.470 34.889 1.00 55.56 O ATOM 1010 OP2 DG C 13 -9.957 -36.165 35.353 1.00 47.91 O ATOM 1011 O5' DG C 13 -11.103 -37.817 33.884 1.00 47.95 O ATOM 1012 C5' DG C 13 -11.639 -39.111 33.558 1.00 45.57 C ATOM 1013 C4' DG C 13 -12.703 -38.979 32.492 1.00 45.79 C ATOM 1014 O4' DG C 13 -13.981 -38.703 33.112 1.00 45.20 O ATOM 1015 C3' DG C 13 -12.481 -37.868 31.461 1.00 45.44 C ATOM 1016 O3' DG C 13 -12.762 -38.422 30.171 1.00 45.87 O ATOM 1017 C2' DG C 13 -13.501 -36.805 31.846 1.00 46.09 C ATOM 1018 C1' DG C 13 -14.629 -37.646 32.422 1.00 45.04 C ATOM 1019 N9 DG C 13 -15.504 -36.967 33.374 1.00 41.99 N ATOM 1020 C8 DG C 13 -15.137 -36.027 34.307 1.00 40.95 C ATOM 1021 N7 DG C 13 -16.136 -35.617 35.041 1.00 41.23 N ATOM 1022 C5 DG C 13 -17.225 -36.344 34.578 1.00 39.83 C ATOM 1023 C6 DG C 13 -18.586 -36.328 34.990 1.00 39.79 C ATOM 1024 O6 DG C 13 -19.114 -35.655 35.882 1.00 41.68 O ATOM 1025 N1 DG C 13 -19.355 -37.216 34.247 1.00 37.64 N ATOM 1026 C2 DG C 13 -18.881 -38.021 33.241 1.00 37.39 C ATOM 1027 N2 DG C 13 -19.785 -38.810 32.642 1.00 34.66 N ATOM 1028 N3 DG C 13 -17.619 -38.039 32.842 1.00 38.57 N ATOM 1029 C4 DG C 13 -16.851 -37.185 33.552 1.00 38.45 C ATOM 1030 P DC C 14 -12.679 -37.624 28.785 1.00 46.85 P ATOM 1031 OP1 DC C 14 -12.333 -38.616 27.736 1.00 47.18 O ATOM 1032 OP2 DC C 14 -11.823 -36.421 28.964 1.00 44.47 O ATOM 1033 O5' DC C 14 -14.186 -37.199 28.490 1.00 44.46 O ATOM 1034 C5' DC C 14 -15.194 -38.195 28.236 1.00 43.53 C ATOM 1035 C4' DC C 14 -16.557 -37.556 28.118 1.00 43.38 C ATOM 1036 O4' DC C 14 -16.994 -37.071 29.413 1.00 43.58 O ATOM 1037 C3' DC C 14 -16.639 -36.358 27.158 1.00 44.67 C ATOM 1038 O3' DC C 14 -17.733 -36.562 26.248 1.00 44.47 O ATOM 1039 C2' DC C 14 -16.867 -35.169 28.081 1.00 44.74 C ATOM 1040 C1' DC C 14 -17.633 -35.819 29.219 1.00 45.36 C ATOM 1041 N1 DC C 14 -17.659 -35.102 30.511 1.00 44.26 N ATOM 1042 C2 DC C 14 -18.865 -35.060 31.223 1.00 42.86 C ATOM 1043 O2 DC C 14 -19.865 -35.619 30.745 1.00 42.36 O ATOM 1044 N3 DC C 14 -18.912 -34.409 32.408 1.00 42.18 N ATOM 1045 C4 DC C 14 -17.817 -33.815 32.886 1.00 44.54 C ATOM 1046 N4 DC C 14 -17.912 -33.190 34.064 1.00 40.98 N ATOM 1047 C5 DC C 14 -16.572 -33.847 32.186 1.00 43.26 C ATOM 1048 C6 DC C 14 -16.540 -34.494 31.012 1.00 43.05 C ATOM 1049 P DG C 15 -18.144 -35.502 25.115 1.00 47.12 P ATOM 1050 OP1 DG C 15 -19.010 -36.145 24.091 1.00 45.56 O ATOM 1051 OP2 DG C 15 -16.898 -34.799 24.708 1.00 43.70 O ATOM 1052 O5' DG C 15 -19.060 -34.436 25.869 1.00 46.84 O ATOM 1053 C5' DG C 15 -20.323 -34.788 26.470 1.00 42.35 C ATOM 1054 C4' DG C 15 -20.898 -33.577 27.171 1.00 40.39 C ATOM 1055 O4' DG C 15 -19.993 -33.136 28.215 1.00 38.98 O ATOM 1056 C3' DG C 15 -21.117 -32.360 26.271 1.00 40.44 C ATOM 1057 O3' DG C 15 -22.267 -31.675 26.752 1.00 41.89 O ATOM 1058 C2' DG C 15 -19.931 -31.469 26.591 1.00 39.36 C ATOM 1059 C1' DG C 15 -19.771 -31.738 28.073 1.00 38.23 C ATOM 1060 N9 DG C 15 -18.460 -31.427 28.633 1.00 36.32 N ATOM 1061 C8 DG C 15 -17.253 -31.445 27.977 1.00 37.79 C ATOM 1062 N7 DG C 15 -16.247 -31.122 28.745 1.00 37.73 N ATOM 1063 C5 DG C 15 -16.823 -30.885 29.985 1.00 37.28 C ATOM 1064 C6 DG C 15 -16.231 -30.495 31.216 1.00 37.32 C ATOM 1065 O6 DG C 15 -15.040 -30.278 31.464 1.00 38.44 O ATOM 1066 N1 DG C 15 -17.181 -30.372 32.224 1.00 36.84 N ATOM 1067 C2 DG C 15 -18.530 -30.575 32.067 1.00 37.70 C ATOM 1068 N2 DG C 15 -19.287 -30.398 33.163 1.00 38.32 N ATOM 1069 N3 DG C 15 -19.096 -30.930 30.924 1.00 38.11 N ATOM 1070 C4 DG C 15 -18.189 -31.066 29.932 1.00 37.67 C HETATM 1071 P DUZ C 16 -23.452 -31.180 25.824 1.00 42.97 P HETATM 1072 N1 DUZ C 16 -21.538 -28.070 29.804 1.00 34.73 N HETATM 1073 C2 DUZ C 16 -20.800 -27.736 30.969 1.00 35.72 C HETATM 1074 O2 DUZ C 16 -21.387 -27.586 32.065 1.00 35.63 O HETATM 1075 N3 DUZ C 16 -19.471 -27.564 30.930 1.00 35.04 N HETATM 1076 C4 DUZ C 16 -18.794 -27.711 29.786 1.00 34.64 C HETATM 1077 O4 DUZ C 16 -17.550 -27.545 29.785 1.00 35.11 O HETATM 1078 C5 DUZ C 16 -19.534 -28.054 28.546 1.00 32.93 C HETATM 1079 C6 DUZ C 16 -20.909 -28.232 28.626 1.00 35.18 C HETATM 1080 C1' DUZ C 16 -22.976 -28.278 29.935 1.00 34.92 C HETATM 1081 C2' DUZ C 16 -23.903 -27.448 29.068 1.00 35.00 C HETATM 1082 C21 DUZ C 16 -18.828 -28.243 27.232 1.00 34.75 C HETATM 1083 O22 DUZ C 16 -19.482 -28.371 26.223 1.00 34.48 O HETATM 1084 N23 DUZ C 16 -17.500 -28.294 27.174 1.00 36.27 N HETATM 1085 C24 DUZ C 16 -16.695 -28.508 25.976 1.00 37.85 C HETATM 1086 C25 DUZ C 16 -16.541 -27.260 25.146 1.00 37.59 C HETATM 1087 C26 DUZ C 16 -17.102 -27.214 23.866 1.00 39.35 C HETATM 1088 C27 DUZ C 16 -16.959 -26.065 23.081 1.00 39.78 C HETATM 1089 C28 DUZ C 16 -16.245 -24.973 23.583 1.00 38.45 C HETATM 1090 C29 DUZ C 16 -15.687 -25.029 24.860 1.00 38.37 C HETATM 1091 C3' DUZ C 16 -25.107 -28.356 28.912 1.00 35.84 C HETATM 1092 O3' DUZ C 16 -26.115 -28.086 29.893 1.00 37.31 O HETATM 1093 C30 DUZ C 16 -15.829 -26.178 25.642 1.00 36.78 C HETATM 1094 C4' DUZ C 16 -24.615 -29.754 29.210 1.00 36.32 C HETATM 1095 O4' DUZ C 16 -23.242 -29.637 29.596 1.00 35.69 O HETATM 1096 C5' DUZ C 16 -24.802 -30.681 28.017 1.00 38.20 C HETATM 1097 O5' DUZ C 16 -24.175 -30.159 26.845 1.00 41.01 O HETATM 1098 OP1 DUZ C 16 -24.390 -32.331 25.594 1.00 40.95 O HETATM 1099 OP2 DUZ C 16 -22.890 -30.382 24.671 1.00 45.42 O HETATM 1100 P UPE C 17 -27.120 -26.850 29.711 1.00 37.67 P HETATM 1101 N1 UPE C 17 -22.128 -24.732 31.999 1.00 33.16 N HETATM 1102 C2 UPE C 17 -20.917 -24.548 32.682 1.00 32.44 C HETATM 1103 O2 UPE C 17 -20.916 -24.557 33.916 1.00 34.12 O HETATM 1104 N3 UPE C 17 -19.762 -24.352 32.037 1.00 34.08 N HETATM 1105 C4 UPE C 17 -19.711 -24.348 30.700 1.00 32.75 C HETATM 1106 O4 UPE C 17 -18.618 -24.174 30.133 1.00 33.14 O HETATM 1107 C5 UPE C 17 -20.964 -24.553 29.935 1.00 32.14 C HETATM 1108 C6 UPE C 17 -22.136 -24.751 30.660 1.00 32.74 C HETATM 1109 C1' UPE C 17 -23.367 -24.973 32.753 1.00 33.87 C HETATM 1110 C2' UPE C 17 -24.016 -23.730 33.338 1.00 35.02 C HETATM 1111 C21 UPE C 17 -21.043 -24.595 28.427 1.00 32.92 C HETATM 1112 O22 UPE C 17 -22.153 -24.700 27.920 1.00 31.24 O HETATM 1113 N23 UPE C 17 -19.974 -24.565 27.629 1.00 32.73 N HETATM 1114 C24 UPE C 17 -20.131 -24.650 26.170 1.00 31.38 C HETATM 1115 C25 UPE C 17 -18.979 -23.894 25.541 1.00 32.98 C HETATM 1116 C26 UPE C 17 -19.161 -22.391 25.515 1.00 31.51 C HETATM 1117 C27 UPE C 17 -18.098 -21.617 25.052 1.00 32.06 C HETATM 1118 C28 UPE C 17 -18.201 -20.221 25.008 1.00 32.31 C HETATM 1119 C29 UPE C 17 -19.376 -19.613 25.439 1.00 31.23 C HETATM 1120 C3' UPE C 17 -25.492 -24.067 33.321 1.00 34.48 C HETATM 1121 O3' UPE C 17 -25.825 -24.630 34.589 1.00 35.80 O HETATM 1122 C30 UPE C 17 -20.435 -20.391 25.908 1.00 32.18 C HETATM 1123 C31 UPE C 17 -20.332 -21.782 25.949 1.00 30.33 C HETATM 1124 C4' UPE C 17 -25.665 -25.155 32.277 1.00 34.62 C HETATM 1125 O4' UPE C 17 -24.351 -25.587 31.920 1.00 33.65 O HETATM 1126 C5' UPE C 17 -26.395 -24.671 31.029 1.00 35.71 C HETATM 1127 O5' UPE C 17 -26.148 -25.601 29.970 1.00 35.71 O HETATM 1128 OP1 UPE C 17 -28.156 -26.950 30.795 1.00 37.30 O HETATM 1129 OP2 UPE C 17 -27.550 -26.814 28.269 1.00 38.45 O HETATM 1130 P 18Q C 18 -27.172 -24.178 35.328 1.00 36.44 P HETATM 1131 N1 18Q C 18 -27.970 -18.837 34.466 1.00 44.14 N HETATM 1132 C2 18Q C 18 -28.395 -17.530 34.106 1.00 44.55 C HETATM 1133 O2 18Q C 18 -28.729 -16.714 34.995 1.00 43.84 O HETATM 1134 N3 18Q C 18 -28.443 -17.149 32.821 1.00 44.63 N HETATM 1135 C4 18Q C 18 -28.081 -17.982 31.838 1.00 45.27 C HETATM 1136 O4 18Q C 18 -28.139 -17.585 30.657 1.00 48.86 O HETATM 1137 C5 18Q C 18 -27.633 -19.367 32.182 1.00 45.30 C HETATM 1138 C6 18Q C 18 -27.588 -19.722 33.530 1.00 43.27 C HETATM 1139 C1' 18Q C 18 -27.922 -19.198 35.885 1.00 42.68 C HETATM 1140 C2' 18Q C 18 -28.970 -20.231 36.279 1.00 41.86 C HETATM 1141 C21 18Q C 18 -27.172 -20.362 31.149 1.00 42.34 C HETATM 1142 O22 18Q C 18 -26.929 -21.503 31.499 1.00 39.99 O HETATM 1143 N23 18Q C 18 -26.956 -19.980 29.892 1.00 41.53 N HETATM 1144 C24 18Q C 18 -26.475 -20.835 28.809 1.00 35.14 C HETATM 1145 C25 18Q C 18 -24.969 -20.700 28.819 1.00 33.36 C HETATM 1146 S26 18Q C 18 -24.053 -22.137 29.020 1.00 35.25 S HETATM 1147 C27 18Q C 18 -22.501 -21.387 28.950 1.00 33.21 C HETATM 1148 C28 18Q C 18 -22.753 -20.028 28.776 1.00 33.77 C HETATM 1149 C29 18Q C 18 -24.095 -19.639 28.705 1.00 32.93 C HETATM 1150 C3' 18Q C 18 -28.282 -20.893 37.461 1.00 42.49 C HETATM 1151 O3' 18Q C 18 -28.560 -20.040 38.583 1.00 44.21 O HETATM 1152 C4' 18Q C 18 -26.788 -20.805 37.166 1.00 40.71 C HETATM 1153 O4' 18Q C 18 -26.634 -19.731 36.237 1.00 42.62 O HETATM 1154 C5' 18Q C 18 -26.165 -22.068 36.573 1.00 39.17 C HETATM 1155 O5' 18Q C 18 -26.961 -22.586 35.499 1.00 36.48 O HETATM 1156 OP1 18Q C 18 -28.342 -24.424 34.413 1.00 34.61 O HETATM 1157 OP2 18Q C 18 -27.141 -24.815 36.696 1.00 40.50 O ATOM 1158 P DA C 19 -28.941 -20.598 40.032 1.00 42.32 P ATOM 1159 OP1 DA C 19 -29.693 -21.874 39.892 1.00 42.16 O ATOM 1160 OP2 DA C 19 -29.545 -19.457 40.765 1.00 46.71 O ATOM 1161 O5' DA C 19 -27.508 -20.872 40.672 1.00 41.02 O ATOM 1162 C5' DA C 19 -26.912 -22.186 40.674 1.00 39.60 C ATOM 1163 C4' DA C 19 -25.422 -22.071 40.911 1.00 38.94 C ATOM 1164 O4' DA C 19 -24.820 -21.268 39.872 1.00 39.27 O ATOM 1165 C3' DA C 19 -25.005 -21.398 42.217 1.00 38.41 C ATOM 1166 O3' DA C 19 -23.691 -21.832 42.579 1.00 37.81 O ATOM 1167 C2' DA C 19 -24.895 -19.934 41.821 1.00 40.50 C ATOM 1168 C1' DA C 19 -24.356 -20.022 40.395 1.00 40.55 C ATOM 1169 N9 DA C 19 -24.813 -18.978 39.479 1.00 42.53 N ATOM 1170 C8 DA C 19 -25.991 -18.274 39.512 1.00 43.99 C ATOM 1171 N7 DA C 19 -26.144 -17.451 38.503 1.00 44.70 N ATOM 1172 C5 DA C 19 -25.004 -17.648 37.737 1.00 43.86 C ATOM 1173 C6 DA C 19 -24.565 -17.080 36.526 1.00 46.08 C ATOM 1174 N6 DA C 19 -25.253 -16.158 35.849 1.00 43.14 N ATOM 1175 N1 DA C 19 -23.378 -17.494 36.031 1.00 44.26 N ATOM 1176 C2 DA C 19 -22.690 -18.422 36.710 1.00 44.52 C ATOM 1177 N3 DA C 19 -22.999 -19.033 37.852 1.00 42.39 N ATOM 1178 C4 DA C 19 -24.182 -18.596 38.319 1.00 43.61 C HETATM 1179 P DUZ C 20 -23.240 -23.361 42.670 1.00 39.62 P HETATM 1180 N1 DUZ C 20 -19.138 -23.659 37.258 1.00 36.48 N HETATM 1181 C2 DUZ C 20 -18.464 -22.948 38.289 1.00 35.75 C HETATM 1182 O2 DUZ C 20 -18.962 -22.839 39.430 1.00 37.35 O HETATM 1183 N3 DUZ C 20 -17.269 -22.391 38.057 1.00 33.60 N HETATM 1184 C4 DUZ C 20 -16.675 -22.482 36.859 1.00 34.09 C HETATM 1185 O4 DUZ C 20 -15.554 -21.959 36.685 1.00 33.89 O HETATM 1186 C5 DUZ C 20 -17.362 -23.204 35.748 1.00 33.42 C HETATM 1187 C6 DUZ C 20 -18.596 -23.766 36.032 1.00 34.78 C HETATM 1188 C1' DUZ C 20 -20.442 -24.291 37.445 1.00 35.97 C HETATM 1189 C2' DUZ C 20 -20.390 -25.489 38.387 1.00 36.13 C HETATM 1190 C21 DUZ C 20 -16.778 -23.349 34.365 1.00 32.11 C HETATM 1191 O22 DUZ C 20 -17.497 -23.782 33.480 1.00 32.64 O HETATM 1192 N23 DUZ C 20 -15.510 -23.016 34.124 1.00 31.56 N HETATM 1193 C24 DUZ C 20 -14.769 -23.090 32.876 1.00 31.50 C HETATM 1194 C25 DUZ C 20 -14.403 -21.692 32.428 1.00 33.66 C HETATM 1195 C26 DUZ C 20 -14.458 -21.371 31.071 1.00 33.13 C HETATM 1196 C27 DUZ C 20 -14.107 -20.091 30.637 1.00 34.03 C HETATM 1197 C28 DUZ C 20 -13.712 -19.128 31.565 1.00 35.43 C HETATM 1198 C29 DUZ C 20 -13.663 -19.448 32.928 1.00 34.26 C HETATM 1199 C3' DUZ C 20 -21.797 -25.519 38.937 1.00 36.85 C HETATM 1200 O3' DUZ C 20 -22.624 -26.242 38.039 1.00 36.21 O HETATM 1201 C30 DUZ C 20 -14.006 -20.729 33.357 1.00 32.45 C HETATM 1202 C4' DUZ C 20 -22.253 -24.070 38.905 1.00 38.04 C HETATM 1203 O4' DUZ C 20 -21.416 -23.397 37.962 1.00 38.56 O HETATM 1204 C5' DUZ C 20 -22.081 -23.401 40.272 1.00 39.11 C HETATM 1205 O5' DUZ C 20 -23.090 -23.883 41.150 1.00 41.04 O HETATM 1206 OP1 DUZ C 20 -21.874 -23.317 43.302 1.00 37.46 O HETATM 1207 OP2 DUZ C 20 -24.372 -24.183 43.222 1.00 40.21 O HETATM 1208 P A2M C 21 -23.300 -27.627 38.456 1.00 36.08 P HETATM 1209 OP1 A2M C 21 -24.339 -27.311 39.502 1.00 36.69 O HETATM 1210 O5' A2M C 21 -24.078 -28.053 37.120 1.00 35.95 O HETATM 1211 C5' A2M C 21 -25.166 -27.254 36.686 1.00 34.99 C HETATM 1212 C4' A2M C 21 -25.870 -27.936 35.531 1.00 38.70 C HETATM 1213 O4' A2M C 21 -24.990 -28.062 34.413 1.00 39.26 O HETATM 1214 C3' A2M C 21 -26.331 -29.365 35.801 1.00 38.81 C HETATM 1215 O3' A2M C 21 -27.550 -29.377 36.552 1.00 41.11 O HETATM 1216 C2' A2M C 21 -26.512 -29.920 34.397 1.00 38.45 C HETATM 1217 O2' A2M C 21 -27.822 -29.537 33.945 1.00 37.94 O HETATM 1218 C1' A2M C 21 -25.446 -29.161 33.615 1.00 36.41 C HETATM 1219 CM' A2M C 21 -28.175 -29.871 32.601 1.00 36.65 C HETATM 1220 N9 A2M C 21 -24.274 -29.950 33.132 1.00 36.06 N HETATM 1221 C8 A2M C 21 -22.978 -29.665 33.399 1.00 35.22 C HETATM 1222 N7 A2M C 21 -22.141 -30.540 32.778 1.00 35.30 N HETATM 1223 C5 A2M C 21 -22.921 -31.406 32.083 1.00 35.21 C HETATM 1224 C6 A2M C 21 -22.687 -32.565 31.180 1.00 35.48 C HETATM 1225 N6 A2M C 21 -21.416 -32.987 30.905 1.00 33.59 N HETATM 1226 N1 A2M C 21 -23.775 -33.190 30.661 1.00 36.69 N HETATM 1227 C2 A2M C 21 -25.038 -32.786 30.921 1.00 36.80 C HETATM 1228 N3 A2M C 21 -25.311 -31.724 31.715 1.00 35.89 N HETATM 1229 C4 A2M C 21 -24.318 -31.011 32.311 1.00 34.83 C HETATM 1230 OP2 A2M C 21 -22.211 -28.636 38.700 1.00 36.87 O ATOM 1231 P DG C 22 -27.865 -30.565 37.575 1.00 40.18 P ATOM 1232 OP1 DG C 22 -29.215 -30.357 38.166 1.00 44.26 O ATOM 1233 OP2 DG C 22 -26.691 -30.754 38.456 1.00 39.55 O ATOM 1234 O5' DG C 22 -27.921 -31.855 36.646 1.00 41.00 O ATOM 1235 C5' DG C 22 -29.032 -32.141 35.782 1.00 38.99 C ATOM 1236 C4' DG C 22 -28.739 -33.418 35.030 1.00 40.43 C ATOM 1237 O4' DG C 22 -27.425 -33.328 34.423 1.00 40.25 O ATOM 1238 C3' DG C 22 -28.710 -34.673 35.902 1.00 41.80 C ATOM 1239 O3' DG C 22 -29.264 -35.768 35.169 1.00 41.43 O ATOM 1240 C2' DG C 22 -27.231 -34.871 36.183 1.00 41.14 C ATOM 1241 C1' DG C 22 -26.573 -34.354 34.910 1.00 40.21 C ATOM 1242 N9 DG C 22 -25.252 -33.772 35.129 1.00 38.86 N ATOM 1243 C8 DG C 22 -24.928 -32.784 36.027 1.00 38.88 C ATOM 1244 N7 DG C 22 -23.659 -32.476 36.016 1.00 38.89 N ATOM 1245 C5 DG C 22 -23.113 -33.305 35.046 1.00 37.41 C ATOM 1246 C6 DG C 22 -21.773 -33.431 34.592 1.00 36.97 C ATOM 1247 O6 DG C 22 -20.769 -32.814 34.972 1.00 33.73 O ATOM 1248 N1 DG C 22 -21.655 -34.415 33.615 1.00 38.24 N ATOM 1249 C2 DG C 22 -22.690 -35.179 33.134 1.00 39.96 C ATOM 1250 N2 DG C 22 -22.377 -36.063 32.176 1.00 39.05 N ATOM 1251 N3 DG C 22 -23.943 -35.070 33.548 1.00 39.79 N ATOM 1252 C4 DG C 22 -24.081 -34.118 34.495 1.00 38.16 C ATOM 1253 P DC C 23 -29.481 -37.237 35.783 1.00 44.35 P ATOM 1254 OP1 DC C 23 -30.835 -37.673 35.359 1.00 44.67 O ATOM 1255 OP2 DC C 23 -29.120 -37.268 37.217 1.00 44.76 O ATOM 1256 O5' DC C 23 -28.396 -38.110 35.014 1.00 43.68 O ATOM 1257 C5' DC C 23 -28.399 -38.210 33.578 1.00 42.35 C ATOM 1258 C4' DC C 23 -27.264 -39.101 33.134 1.00 43.94 C ATOM 1259 O4' DC C 23 -26.012 -38.407 33.318 1.00 43.02 O ATOM 1260 C3' DC C 23 -27.149 -40.424 33.895 1.00 45.31 C ATOM 1261 O3' DC C 23 -27.074 -41.479 32.940 1.00 50.49 O ATOM 1262 C2' DC C 23 -25.858 -40.301 34.692 1.00 45.69 C ATOM 1263 C1' DC C 23 -25.058 -39.246 33.947 1.00 44.16 C ATOM 1264 N1 DC C 23 -24.212 -38.386 34.794 1.00 44.80 N ATOM 1265 C2 DC C 23 -22.836 -38.317 34.541 1.00 45.48 C ATOM 1266 O2 DC C 23 -22.352 -39.024 33.643 1.00 46.07 O ATOM 1267 N3 DC C 23 -22.066 -37.499 35.294 1.00 45.87 N ATOM 1268 C4 DC C 23 -22.623 -36.754 36.252 1.00 45.38 C ATOM 1269 N4 DC C 23 -21.824 -35.961 36.972 1.00 42.07 N ATOM 1270 C5 DC C 23 -24.023 -36.793 36.521 1.00 44.78 C ATOM 1271 C6 DC C 23 -24.774 -37.610 35.770 1.00 45.54 C HETATM 1272 P 18M C 24 -27.415 -42.994 33.302 1.00 50.38 P HETATM 1273 O5' 18M C 24 -25.955 -43.567 33.626 1.00 52.08 O HETATM 1274 C5' 18M C 24 -25.085 -43.890 32.547 1.00 51.96 C HETATM 1275 C4' 18M C 24 -23.697 -44.196 33.082 1.00 54.82 C HETATM 1276 O4' 18M C 24 -23.164 -43.037 33.735 1.00 53.95 O HETATM 1277 C3' 18M C 24 -23.689 -45.327 34.098 1.00 56.55 C HETATM 1278 O3' 18M C 24 -22.585 -46.178 33.779 1.00 62.74 O HETATM 1279 C2' 18M C 24 -23.403 -44.631 35.425 1.00 54.87 C HETATM 1280 O2' 18M C 24 -22.767 -45.504 36.380 1.00 56.12 O HETATM 1281 C1' 18M C 24 -22.587 -43.418 34.983 1.00 51.66 C HETATM 1282 N9 18M C 24 -22.575 -42.269 35.923 1.00 50.61 N HETATM 1283 C8 18M C 24 -23.570 -41.815 36.713 1.00 49.45 C HETATM 1284 N7 18M C 24 -23.172 -40.725 37.420 1.00 45.53 N HETATM 1285 C5 18M C 24 -21.900 -40.471 37.072 1.00 46.52 C HETATM 1286 C6 18M C 24 -20.861 -39.480 37.434 1.00 46.93 C HETATM 1287 O6 18M C 24 -21.104 -38.583 38.269 1.00 47.47 O HETATM 1288 N1 18M C 24 -19.659 -39.565 36.833 1.00 46.50 N HETATM 1289 C2 18M C 24 -19.367 -40.520 35.925 1.00 46.83 C HETATM 1290 N2 18M C 24 -18.134 -40.547 35.361 1.00 44.74 N HETATM 1291 N3 18M C 24 -20.271 -41.460 35.559 1.00 45.43 N HETATM 1292 C4 18M C 24 -21.517 -41.485 36.085 1.00 46.35 C HETATM 1293 P1 18M C 24 -22.688 -47.402 32.759 1.00 69.14 P HETATM 1294 O11 18M C 24 -22.576 -46.865 31.379 1.00 64.22 O HETATM 1295 O12 18M C 24 -21.358 -48.204 33.113 1.00 69.22 O HETATM 1296 O13 18M C 24 -23.860 -48.239 33.134 1.00 69.46 O HETATM 1297 CM2 18M C 24 -21.343 -45.720 36.296 1.00 57.29 C HETATM 1298 OP1 18M C 24 -27.890 -43.627 32.024 1.00 54.47 O HETATM 1299 OP2 18M C 24 -28.293 -43.027 34.521 1.00 53.83 O TER 1300 18M C 24 CONECT 63 415 CONECT 339 711 CONECT 361 726 CONECT 415 63 CONECT 711 339 CONECT 726 361 CONECT 744 745 751 752 CONECT 745 744 746 747 CONECT 746 745 CONECT 747 745 748 CONECT 748 747 749 750 CONECT 749 748 CONECT 750 748 751 754 CONECT 751 744 750 CONECT 752 744 753 767 CONECT 753 752 763 CONECT 754 750 755 756 CONECT 755 754 CONECT 756 754 757 CONECT 757 756 758 CONECT 758 757 759 765 CONECT 759 758 760 CONECT 760 759 761 CONECT 761 760 762 CONECT 762 761 765 CONECT 763 753 764 766 CONECT 764 763 CONECT 765 758 762 CONECT 766 763 767 768 CONECT 767 752 766 CONECT 768 766 769 CONECT 769 768 CONECT 770 796 797 798 CONECT 771 772 778 779 CONECT 772 771 773 774 CONECT 773 772 CONECT 774 772 775 CONECT 775 774 776 777 CONECT 776 775 CONECT 777 775 778 781 CONECT 778 771 777 CONECT 779 771 780 794 CONECT 780 779 790 CONECT 781 777 782 783 CONECT 782 781 CONECT 783 781 784 CONECT 784 783 785 CONECT 785 784 786 792 CONECT 786 785 787 CONECT 787 786 788 CONECT 788 787 789 CONECT 789 788 792 CONECT 790 780 791 793 CONECT 791 790 CONECT 792 785 789 CONECT 793 790 794 795 CONECT 794 779 793 CONECT 795 793 796 CONECT 796 770 795 CONECT 797 770 CONECT 798 770 CONECT 799 800 801 821 CONECT 800 799 CONECT 801 799 802 CONECT 802 801 803 CONECT 803 802 804 805 CONECT 804 803 809 CONECT 805 803 806 807 CONECT 806 805 CONECT 807 805 808 809 CONECT 808 807 810 CONECT 809 804 807 811 CONECT 810 808 CONECT 811 809 812 820 CONECT 812 811 813 CONECT 813 812 814 CONECT 814 813 815 820 CONECT 815 814 816 817 CONECT 816 815 CONECT 817 815 818 CONECT 818 817 819 CONECT 819 818 820 CONECT 820 811 814 819 CONECT 821 799 CONECT 830 842 CONECT 841 842 CONECT 842 830 841 843 844 CONECT 843 842 CONECT 844 842 CONECT 845 846 CONECT 846 845 CONECT 854 868 CONECT 868 854 894 895 896 CONECT 869 870 876 877 CONECT 870 869 871 872 CONECT 871 870 CONECT 872 870 873 CONECT 873 872 874 875 CONECT 874 873 CONECT 875 873 876 879 CONECT 876 869 875 CONECT 877 869 878 892 CONECT 878 877 888 CONECT 879 875 880 881 CONECT 880 879 CONECT 881 879 882 CONECT 882 881 883 CONECT 883 882 884 890 CONECT 884 883 885 CONECT 885 884 886 CONECT 886 885 887 CONECT 887 886 890 CONECT 888 878 889 891 CONECT 889 888 CONECT 890 883 887 CONECT 891 888 892 893 CONECT 892 877 891 CONECT 893 891 894 CONECT 894 868 893 CONECT 895 868 CONECT 896 868 CONECT 897 923 924 925 CONECT 898 899 905 906 CONECT 899 898 900 901 CONECT 900 899 CONECT 901 899 902 CONECT 902 901 903 904 CONECT 903 902 CONECT 904 902 905 908 CONECT 905 898 904 CONECT 906 898 907 921 CONECT 907 906 917 CONECT 908 904 909 910 CONECT 909 908 CONECT 910 908 911 CONECT 911 910 912 CONECT 912 911 913 919 CONECT 913 912 914 CONECT 914 913 915 CONECT 915 914 916 CONECT 916 915 919 CONECT 917 907 918 920 CONECT 918 917 CONECT 919 912 916 CONECT 920 917 921 922 CONECT 921 906 920 CONECT 922 920 923 CONECT 923 897 922 CONECT 924 897 CONECT 925 897 CONECT 953 1301 CONECT 955 966 CONECT 960 1301 CONECT 966 955 967 968 988 CONECT 967 966 CONECT 968 966 969 CONECT 969 968 970 CONECT 970 969 971 972 CONECT 971 970 976 CONECT 972 970 973 974 CONECT 973 972 CONECT 974 972 975 976 CONECT 975 974 977 CONECT 976 971 974 978 CONECT 977 975 CONECT 978 976 979 987 CONECT 979 978 980 CONECT 980 979 981 CONECT 981 980 982 987 CONECT 982 981 983 984 CONECT 983 982 CONECT 984 982 985 CONECT 985 984 986 CONECT 986 985 987 CONECT 987 978 981 986 CONECT 988 966 CONECT 1057 1071 CONECT 1071 1057 1097 1098 1099 CONECT 1072 1073 1079 1080 CONECT 1073 1072 1074 1075 CONECT 1074 1073 CONECT 1075 1073 1076 CONECT 1076 1075 1077 1078 CONECT 1077 1076 CONECT 1078 1076 1079 1082 CONECT 1079 1072 1078 CONECT 1080 1072 1081 1095 CONECT 1081 1080 1091 CONECT 1082 1078 1083 1084 CONECT 1083 1082 CONECT 1084 1082 1085 CONECT 1085 1084 1086 CONECT 1086 1085 1087 1093 CONECT 1087 1086 1088 CONECT 1088 1087 1089 CONECT 1089 1088 1090 CONECT 1090 1089 1093 CONECT 1091 1081 1092 1094 CONECT 1092 1091 CONECT 1093 1086 1090 CONECT 1094 1091 1095 1096 CONECT 1095 1080 1094 CONECT 1096 1094 1097 CONECT 1097 1071 1096 CONECT 1098 1071 CONECT 1099 1071 CONECT 1100 1127 1128 1129 CONECT 1101 1102 1108 1109 CONECT 1102 1101 1103 1104 CONECT 1103 1102 CONECT 1104 1102 1105 CONECT 1105 1104 1106 1107 CONECT 1106 1105 CONECT 1107 1105 1108 1111 CONECT 1108 1101 1107 CONECT 1109 1101 1110 1125 CONECT 1110 1109 1120 CONECT 1111 1107 1112 1113 CONECT 1112 1111 CONECT 1113 1111 1114 CONECT 1114 1113 1115 CONECT 1115 1114 1116 CONECT 1116 1115 1117 1123 CONECT 1117 1116 1118 CONECT 1118 1117 1119 CONECT 1119 1118 1122 CONECT 1120 1110 1121 1124 CONECT 1121 1120 CONECT 1122 1119 1123 CONECT 1123 1116 1122 CONECT 1124 1120 1125 1126 CONECT 1125 1109 1124 CONECT 1126 1124 1127 CONECT 1127 1100 1126 CONECT 1128 1100 CONECT 1129 1100 CONECT 1130 1155 1156 1157 CONECT 1131 1132 1138 1139 CONECT 1132 1131 1133 1134 CONECT 1133 1132 CONECT 1134 1132 1135 CONECT 1135 1134 1136 1137 CONECT 1136 1135 CONECT 1137 1135 1138 1141 CONECT 1138 1131 1137 CONECT 1139 1131 1140 1153 CONECT 1140 1139 1150 CONECT 1141 1137 1142 1143 CONECT 1142 1141 CONECT 1143 1141 1144 CONECT 1144 1143 1145 CONECT 1145 1144 1146 1149 CONECT 1146 1145 1147 CONECT 1147 1146 1148 CONECT 1148 1147 1149 CONECT 1149 1145 1148 CONECT 1150 1140 1151 1152 CONECT 1151 1150 CONECT 1152 1150 1153 1154 CONECT 1153 1139 1152 CONECT 1154 1152 1155 CONECT 1155 1130 1154 CONECT 1156 1130 CONECT 1157 1130 CONECT 1166 1179 CONECT 1179 1166 1205 1206 1207 CONECT 1180 1181 1187 1188 CONECT 1181 1180 1182 1183 CONECT 1182 1181 CONECT 1183 1181 1184 CONECT 1184 1183 1185 1186 CONECT 1185 1184 CONECT 1186 1184 1187 1190 CONECT 1187 1180 1186 CONECT 1188 1180 1189 1203 CONECT 1189 1188 1199 CONECT 1190 1186 1191 1192 CONECT 1191 1190 CONECT 1192 1190 1193 CONECT 1193 1192 1194 CONECT 1194 1193 1195 1201 CONECT 1195 1194 1196 CONECT 1196 1195 1197 CONECT 1197 1196 1198 CONECT 1198 1197 1201 CONECT 1199 1189 1200 1202 CONECT 1200 1199 CONECT 1201 1194 1198 CONECT 1202 1199 1203 1204 CONECT 1203 1188 1202 CONECT 1204 1202 1205 CONECT 1205 1179 1204 CONECT 1206 1179 CONECT 1207 1179 CONECT 1208 1209 1210 1230 CONECT 1209 1208 CONECT 1210 1208 1211 CONECT 1211 1210 1212 CONECT 1212 1211 1213 1214 CONECT 1213 1212 1218 CONECT 1214 1212 1215 1216 CONECT 1215 1214 CONECT 1216 1214 1217 1218 CONECT 1217 1216 1219 CONECT 1218 1213 1216 1220 CONECT 1219 1217 CONECT 1220 1218 1221 1229 CONECT 1221 1220 1222 CONECT 1222 1221 1223 CONECT 1223 1222 1224 1229 CONECT 1224 1223 1225 1226 CONECT 1225 1224 CONECT 1226 1224 1227 CONECT 1227 1226 1228 CONECT 1228 1227 1229 CONECT 1229 1220 1223 1228 CONECT 1230 1208 CONECT 1247 1301 CONECT 1272 1273 1298 1299 CONECT 1273 1272 1274 CONECT 1274 1273 1275 CONECT 1275 1274 1276 1277 CONECT 1276 1275 1281 CONECT 1277 1275 1278 1279 CONECT 1278 1277 1293 CONECT 1279 1277 1280 1281 CONECT 1280 1279 1297 CONECT 1281 1276 1279 1282 CONECT 1282 1281 1283 1292 CONECT 1283 1282 1284 CONECT 1284 1283 1285 CONECT 1285 1284 1286 1292 CONECT 1286 1285 1287 1288 CONECT 1287 1286 CONECT 1288 1286 1289 CONECT 1289 1288 1290 1291 CONECT 1290 1289 CONECT 1291 1289 1292 CONECT 1292 1282 1285 1291 CONECT 1293 1278 1294 1295 1296 CONECT 1294 1293 CONECT 1295 1293 CONECT 1296 1293 CONECT 1297 1280 CONECT 1298 1272 CONECT 1299 1272 CONECT 1301 953 960 1247 1362 CONECT 1301 1363 1364 CONECT 1302 1349 1350 1351 1352 CONECT 1302 1353 1354 CONECT 1349 1302 CONECT 1350 1302 CONECT 1351 1302 CONECT 1352 1302 CONECT 1353 1302 CONECT 1354 1302 CONECT 1362 1301 CONECT 1363 1301 CONECT 1364 1301 MASTER 348 0 15 1 5 0 4 6 1378 2 359 11 END If you find results from this site helpful for your research, please cite one of our papers:
elNémo
is maintained by Yves-Henri Sanejouand. |