CNRS Nantes University US2B US2B
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Should you encounter any unexpected behaviour,
please let us know.
 elNémo has been hacked on november 27th.
It has been moved away and runs again.
**Still some additional cleaning from time to time**
Sorry for the inconvenience.


***  TRANSFERASE 18-AUG-21 7PHT  ***

CA strain for 2602051053402635744

---  normal mode 7  ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA iCA i+1vari
ASN 953ILE 954 -0.0001
ILE 954ALA 955 -0.0000
ALA 955LYS 956 -0.0002
LYS 956ILE 957 0.0016
ILE 957ILE 958 -0.0002
ILE 958ILE 959 -0.0003
ILE 959GLY 960 0.0002
GLY 960PRO 961 -0.0034
PRO 961LEU 962 0.0003
LEU 962ILE 963 0.0005
ILE 963PHE 964 0.0001
PHE 964VAL 965 -0.0017
VAL 965PHE 966 -0.0000
PHE 966LEU 967 0.0002
LEU 967PHE 968 0.0001
PHE 968SER 969 0.0008
SER 969VAL 970 -0.0002
VAL 970VAL 971 -0.0002
VAL 971ILE 972 0.0001
ILE 972GLY 973 0.0205
GLY 973SER 974 0.0004
SER 974ILE 975 -0.0001
ILE 975TYR 976 -0.0000
TYR 976LEU 977 0.0058
LEU 977PHE 978 -0.0001
PHE 978LEU 979 -0.0001
LEU 979ARG 980 0.0001
ARG 980LYS 981 0.0149
LYS 981ARG 982 0.0000
ARG 982ASN 953 0.0191
ASN 953ILE 954 0.0002
ILE 954ALA 955 0.0002
ALA 955LYS 956 0.0002
LYS 956ILE 957 0.0008
ILE 957ILE 958 0.0000
ILE 958ILE 959 0.0001
ILE 959GLY 960 -0.0000
GLY 960PRO 961 -0.0084
PRO 961LEU 962 0.0002
LEU 962ILE 963 -0.0001
ILE 963PHE 964 0.0004
PHE 964VAL 965 -0.0016
VAL 965PHE 966 -0.0000
PHE 966LEU 967 -0.0001
LEU 967PHE 968 0.0003
PHE 968SER 969 -0.0023
SER 969VAL 970 0.0003
VAL 970VAL 971 0.0004
VAL 971ILE 972 -0.0000
ILE 972GLY 973 0.0191
GLY 973SER 974 0.0000
SER 974ILE 975 -0.0000
ILE 975TYR 976 0.0001
TYR 976LEU 977 0.0076
LEU 977PHE 978 0.0002
PHE 978LEU 979 -0.0000
LEU 979ARG 980 -0.0002
ARG 980LYS 981 0.0134
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0162
ASN 953ILE 954 0.0002
ILE 954ALA 955 0.0001
ALA 955LYS 956 -0.0003
LYS 956ILE 957 0.0022
ILE 957ILE 958 -0.0002
ILE 958ILE 959 -0.0001
ILE 959GLY 960 0.0001
GLY 960PRO 961 0.0012
PRO 961LEU 962 -0.0001
LEU 962ILE 963 0.0000
ILE 963PHE 964 -0.0003
PHE 964VAL 965 0.0032
VAL 965PHE 966 0.0002
PHE 966LEU 967 -0.0003
LEU 967PHE 968 0.0001
PHE 968SER 969 -0.0005
SER 969VAL 970 0.0000
VAL 970VAL 971 -0.0003
VAL 971ILE 972 0.0003
ILE 972GLY 973 0.0086
GLY 973SER 974 0.0004
SER 974ILE 975 0.0001
ILE 975TYR 976 0.0002
TYR 976LEU 977 0.0034
LEU 977PHE 978 -0.0000
PHE 978LEU 979 -0.0006
LEU 979ARG 980 0.0001
ARG 980LYS 981 0.0053
LYS 981ARG 982 0.0002
ARG 982ASN 953 0.0350
ASN 953ILE 954 0.0003
ILE 954ALA 955 0.0002
ALA 955LYS 956 0.0002
LYS 956ILE 957 0.0007
ILE 957ILE 958 0.0000
ILE 958ILE 959 0.0002
ILE 959GLY 960 -0.0001
GLY 960PRO 961 -0.0052
PRO 961LEU 962 -0.0000
LEU 962ILE 963 -0.0001
ILE 963PHE 964 -0.0003
PHE 964VAL 965 -0.0003
VAL 965PHE 966 0.0002
PHE 966LEU 967 -0.0005
LEU 967PHE 968 0.0004
PHE 968SER 969 -0.0023
SER 969VAL 970 -0.0000
VAL 970VAL 971 0.0003
VAL 971ILE 972 -0.0000
ILE 972GLY 973 0.0083
GLY 973SER 974 0.0001
SER 974ILE 975 0.0001
ILE 975TYR 976 0.0002
TYR 976LEU 977 0.0117
LEU 977PHE 978 -0.0000
PHE 978LEU 979 -0.0001
LEU 979ARG 980 0.0001
ARG 980LYS 981 0.0090
LYS 981ARG 982 -0.0001
ARG 982ASN 953 0.0166
ASN 953ILE 954 0.0002
ILE 954ALA 955 -0.0001
ALA 955LYS 956 -0.0000
LYS 956ILE 957 0.0017
ILE 957ILE 958 -0.0001
ILE 958ILE 959 0.0002
ILE 959GLY 960 0.0003
GLY 960PRO 961 -0.0064
PRO 961LEU 962 -0.0002
LEU 962ILE 963 -0.0002
ILE 963PHE 964 -0.0003
PHE 964VAL 965 0.0054
VAL 965PHE 966 0.0000
PHE 966LEU 967 0.0003
LEU 967PHE 968 -0.0002
PHE 968SER 969 0.0042
SER 969VAL 970 -0.0000
VAL 970VAL 971 0.0001
VAL 971ILE 972 -0.0000
ILE 972GLY 973 0.0079
GLY 973SER 974 -0.0003
SER 974ILE 975 0.0006
ILE 975TYR 976 0.0002
TYR 976LEU 977 0.0047
LEU 977PHE 978 0.0001
PHE 978LEU 979 -0.0002
LEU 979ARG 980 -0.0000
ARG 980LYS 981 0.0177
LYS 981ARG 982 -0.0001
ARG 982ASN 953 0.0262
ASN 953ILE 954 -0.0005
ILE 954ALA 955 0.0002
ALA 955LYS 956 -0.0003
LYS 956ILE 957 0.0008
ILE 957ILE 958 -0.0003
ILE 958ILE 959 -0.0002
ILE 959GLY 960 -0.0004
GLY 960PRO 961 -0.0058
PRO 961LEU 962 -0.0000
LEU 962ILE 963 0.0002
ILE 963PHE 964 -0.0002
PHE 964VAL 965 -0.0006
VAL 965PHE 966 -0.0004
PHE 966LEU 967 -0.0004
LEU 967PHE 968 0.0000
PHE 968SER 969 0.0078
SER 969VAL 970 0.0001
VAL 970VAL 971 -0.0003
VAL 971ILE 972 0.0002
ILE 972GLY 973 0.0136
GLY 973SER 974 0.0002
SER 974ILE 975 -0.0003
ILE 975TYR 976 0.0002
TYR 976LEU 977 0.0058
LEU 977PHE 978 -0.0000
PHE 978LEU 979 0.0002
LEU 979ARG 980 0.0001
ARG 980LYS 981 0.0174
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0323
ASN 953ILE 954 0.0000
ILE 954ALA 955 -0.0003
ALA 955LYS 956 -0.0002
LYS 956ILE 957 -0.0004
ILE 957ILE 958 0.0001
ILE 958ILE 959 0.0003
ILE 959GLY 960 0.0002
GLY 960PRO 961 -0.0057
PRO 961LEU 962 0.0000
LEU 962ILE 963 -0.0002
ILE 963PHE 964 0.0001
PHE 964VAL 965 0.0041
VAL 965PHE 966 0.0002
PHE 966LEU 967 -0.0003
LEU 967PHE 968 -0.0004
PHE 968SER 969 0.0040
SER 969VAL 970 0.0001
VAL 970VAL 971 -0.0002
VAL 971ILE 972 0.0003
ILE 972GLY 973 0.0184
GLY 973SER 974 -0.0001
SER 974ILE 975 -0.0004
ILE 975TYR 976 -0.0001
TYR 976LEU 977 0.0012
LEU 977PHE 978 0.0001
PHE 978LEU 979 -0.0001
LEU 979ARG 980 -0.0001
ARG 980LYS 981 0.0130
LYS 981ARG 982 -0.0001
ARG 982ASN 953 0.0295
ASN 953ILE 954 0.0003
ILE 954ALA 955 0.0002
ALA 955LYS 956 0.0002
LYS 956ILE 957 0.0003
ILE 957ILE 958 -0.0000
ILE 958ILE 959 0.0003
ILE 959GLY 960 -0.0002
GLY 960PRO 961 -0.0054
PRO 961LEU 962 -0.0002
LEU 962ILE 963 -0.0002
ILE 963PHE 964 0.0001
PHE 964VAL 965 0.0034
VAL 965PHE 966 0.0001
PHE 966LEU 967 0.0004
LEU 967PHE 968 -0.0002
PHE 968SER 969 0.0003
SER 969VAL 970 0.0003
VAL 970VAL 971 0.0002
VAL 971ILE 972 -0.0000
ILE 972GLY 973 0.0159
GLY 973SER 974 -0.0000
SER 974ILE 975 0.0002
ILE 975TYR 976 0.0004
TYR 976LEU 977 0.0063
LEU 977PHE 978 0.0003
PHE 978LEU 979 0.0003
LEU 979ARG 980 0.0000
ARG 980LYS 981 0.0159
LYS 981ARG 982 -0.0001
ARG 982ASN 953 0.0126
ASN 953ILE 954 0.0002
ILE 954ALA 955 -0.0002
ALA 955LYS 956 -0.0001
LYS 956ILE 957 0.0039
ILE 957ILE 958 0.0001
ILE 958ILE 959 0.0002
ILE 959GLY 960 -0.0003
GLY 960PRO 961 -0.0007
PRO 961LEU 962 0.0001
LEU 962ILE 963 0.0004
ILE 963PHE 964 0.0002
PHE 964VAL 965 0.0030
VAL 965PHE 966 0.0001
PHE 966LEU 967 -0.0005
LEU 967PHE 968 -0.0000
PHE 968SER 969 0.0029
SER 969VAL 970 -0.0003
VAL 970VAL 971 -0.0003
VAL 971ILE 972 0.0000
ILE 972GLY 973 -0.0000
GLY 973SER 974 -0.0003
SER 974ILE 975 0.0002
ILE 975TYR 976 -0.0001
TYR 976LEU 977 0.0080
LEU 977PHE 978 -0.0002
PHE 978LEU 979 0.0000
LEU 979ARG 980 -0.0001
ARG 980LYS 981 0.0097
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0334
ASN 953ILE 954 0.0001
ILE 954ALA 955 0.0001
ALA 955LYS 956 0.0005
LYS 956ILE 957 0.0009
ILE 957ILE 958 0.0000
ILE 958ILE 959 0.0000
ILE 959GLY 960 -0.0002
GLY 960PRO 961 -0.0076
PRO 961LEU 962 0.0000
LEU 962ILE 963 0.0002
ILE 963PHE 964 0.0001
PHE 964VAL 965 0.0028
VAL 965PHE 966 0.0001
PHE 966LEU 967 0.0002
LEU 967PHE 968 -0.0001
PHE 968SER 969 0.0013
SER 969VAL 970 -0.0001
VAL 970VAL 971 -0.0000
VAL 971ILE 972 -0.0001
ILE 972GLY 973 0.0148
GLY 973SER 974 0.0000
SER 974ILE 975 -0.0000
ILE 975TYR 976 0.0001
TYR 976LEU 977 0.0072
LEU 977PHE 978 -0.0001
PHE 978LEU 979 0.0000
LEU 979ARG 980 -0.0000
ARG 980LYS 981 0.0223
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0393
ASN 953ILE 954 -0.0003
ILE 954ALA 955 0.0000
ALA 955LYS 956 0.0002
LYS 956ILE 957 0.0003
ILE 957ILE 958 0.0002
ILE 958ILE 959 -0.0001
ILE 959GLY 960 0.0000
GLY 960PRO 961 -0.0030
PRO 961LEU 962 -0.0000
LEU 962ILE 963 -0.0002
ILE 963PHE 964 0.0004
PHE 964VAL 965 0.0047
VAL 965PHE 966 -0.0001
PHE 966LEU 967 -0.0000
LEU 967PHE 968 0.0000
PHE 968SER 969 -0.0004
SER 969VAL 970 0.0000
VAL 970VAL 971 -0.0002
VAL 971ILE 972 -0.0001
ILE 972GLY 973 0.0068
GLY 973SER 974 -0.0002
SER 974ILE 975 -0.0004
ILE 975TYR 976 -0.0000
TYR 976LEU 977 0.0133
LEU 977PHE 978 0.0003
PHE 978LEU 979 -0.0004
LEU 979ARG 980 0.0000
ARG 980LYS 981 0.0244
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0282
ASN 953ILE 954 -0.0003
ILE 954ALA 955 -0.0003
ALA 955LYS 956 -0.0002
LYS 956ILE 957 0.0019
ILE 957ILE 958 -0.0004
ILE 958ILE 959 0.0001
ILE 959GLY 960 0.0001
GLY 960PRO 961 -0.0012
PRO 961LEU 962 0.0002
LEU 962ILE 963 0.0004
ILE 963PHE 964 -0.0002
PHE 964VAL 965 0.0030
VAL 965PHE 966 0.0001
PHE 966LEU 967 -0.0004
LEU 967PHE 968 0.0002
PHE 968SER 969 -0.0010
SER 969VAL 970 -0.0003
VAL 970VAL 971 -0.0004
VAL 971ILE 972 -0.0004
ILE 972GLY 973 0.0128
GLY 973SER 974 0.0002
SER 974ILE 975 0.0001
ILE 975TYR 976 0.0002
TYR 976LEU 977 0.0037
LEU 977PHE 978 0.0001
PHE 978LEU 979 -0.0002
LEU 979ARG 980 -0.0004
ARG 980LYS 981 0.0165
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0377
ASN 953ILE 954 0.0005
ILE 954ALA 955 -0.0003
ALA 955LYS 956 0.0001
LYS 956ILE 957 0.0022
ILE 957ILE 958 0.0000
ILE 958ILE 959 0.0002
ILE 959GLY 960 0.0000
GLY 960PRO 961 -0.0083
PRO 961LEU 962 -0.0002
LEU 962ILE 963 0.0000
ILE 963PHE 964 -0.0003
PHE 964VAL 965 0.0007
VAL 965PHE 966 0.0003
PHE 966LEU 967 -0.0003
LEU 967PHE 968 -0.0002
PHE 968SER 969 -0.0007
SER 969VAL 970 -0.0001
VAL 970VAL 971 0.0001
VAL 971ILE 972 -0.0002
ILE 972GLY 973 0.0078
GLY 973SER 974 0.0003
SER 974ILE 975 0.0001
ILE 975TYR 976 0.0003
TYR 976LEU 977 0.0132
LEU 977PHE 978 0.0000
PHE 978LEU 979 -0.0001
LEU 979ARG 980 -0.0002
ARG 980LYS 981 0.0211
LYS 981ARG 982 -0.0003
ARG 982ASN 953 0.0267
ASN 953ILE 954 0.0003
ILE 954ALA 955 -0.0002
ALA 955LYS 956 0.0000
LYS 956ILE 957 0.0021
ILE 957ILE 958 -0.0000
ILE 958ILE 959 0.0002
ILE 959GLY 960 0.0001
GLY 960PRO 961 0.0030
PRO 961LEU 962 0.0001
LEU 962ILE 963 -0.0005
ILE 963PHE 964 0.0000
PHE 964VAL 965 0.0057
VAL 965PHE 966 0.0002
PHE 966LEU 967 -0.0002
LEU 967PHE 968 0.0002
PHE 968SER 969 0.0080
SER 969VAL 970 -0.0003
VAL 970VAL 971 0.0001
VAL 971ILE 972 0.0001
ILE 972GLY 973 -0.0038
GLY 973SER 974 0.0001
SER 974ILE 975 -0.0004
ILE 975TYR 976 -0.0001
TYR 976LEU 977 0.0082
LEU 977PHE 978 -0.0002
PHE 978LEU 979 -0.0000
LEU 979ARG 980 -0.0005
ARG 980LYS 981 0.0055
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0205
ASN 953ILE 954 -0.0002
ILE 954ALA 955 0.0001
ALA 955LYS 956 0.0002
LYS 956ILE 957 -0.0013
ILE 957ILE 958 -0.0004
ILE 958ILE 959 -0.0001
ILE 959GLY 960 -0.0001
GLY 960PRO 961 -0.0061
PRO 961LEU 962 -0.0005
LEU 962ILE 963 0.0000
ILE 963PHE 964 0.0001
PHE 964VAL 965 -0.0024
VAL 965PHE 966 0.0001
PHE 966LEU 967 -0.0001
LEU 967PHE 968 -0.0000
PHE 968SER 969 -0.0035
SER 969VAL 970 0.0001
VAL 970VAL 971 -0.0002
VAL 971ILE 972 -0.0001
ILE 972GLY 973 0.0194
GLY 973SER 974 -0.0003
SER 974ILE 975 -0.0002
ILE 975TYR 976 0.0000
TYR 976LEU 977 0.0102
LEU 977PHE 978 -0.0002
PHE 978LEU 979 0.0000
LEU 979ARG 980 0.0004
ARG 980LYS 981 0.0261
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0278
ASN 953ILE 954 -0.0000
ILE 954ALA 955 0.0002
ALA 955LYS 956 0.0000
LYS 956ILE 957 0.0016
ILE 957ILE 958 0.0000
ILE 958ILE 959 0.0002
ILE 959GLY 960 0.0002
GLY 960PRO 961 -0.0038
PRO 961LEU 962 -0.0002
LEU 962ILE 963 -0.0002
ILE 963PHE 964 0.0003
PHE 964VAL 965 0.0045
VAL 965PHE 966 0.0001
PHE 966LEU 967 -0.0001
LEU 967PHE 968 0.0000
PHE 968SER 969 0.0086
SER 969VAL 970 0.0001
VAL 970VAL 971 -0.0001
VAL 971ILE 972 0.0004
ILE 972GLY 973 0.0079
GLY 973SER 974 0.0000
SER 974ILE 975 0.0003
ILE 975TYR 976 0.0002
TYR 976LEU 977 0.0080
LEU 977PHE 978 0.0001
PHE 978LEU 979 0.0002
LEU 979ARG 980 -0.0000
ARG 980LYS 981 0.0148
LYS 981ARG 982 0.0001
ARG 982ASN 953 0.0319
ASN 953ILE 954 -0.0002
ILE 954ALA 955 -0.0003
ALA 955LYS 956 0.0004
LYS 956ILE 957 -0.0014
ILE 957ILE 958 -0.0002
ILE 958ILE 959 0.0001
ILE 959GLY 960 0.0002
GLY 960PRO 961 -0.0056
PRO 961LEU 962 -0.0001
LEU 962ILE 963 0.0002
ILE 963PHE 964 -0.0004
PHE 964VAL 965 0.0002
VAL 965PHE 966 0.0000
PHE 966LEU 967 -0.0004
LEU 967PHE 968 0.0001
PHE 968SER 969 -0.0025
SER 969VAL 970 0.0003
VAL 970VAL 971 -0.0003
VAL 971ILE 972 0.0001
ILE 972GLY 973 0.0154
GLY 973SER 974 -0.0001
SER 974ILE 975 -0.0001
ILE 975TYR 976 0.0001
TYR 976LEU 977 0.0034
LEU 977PHE 978 -0.0001
PHE 978LEU 979 0.0000
LEU 979ARG 980 0.0000
ARG 980LYS 981 0.0162
LYS 981ARG 982 -0.0000
ARG 982ASN 953 0.0318
ASN 953ILE 954 0.0004
ILE 954ALA 955 -0.0003
ALA 955LYS 956 0.0002
LYS 956ILE 957 0.0000
ILE 957ILE 958 -0.0001
ILE 958ILE 959 0.0002
ILE 959GLY 960 0.0003
GLY 960PRO 961 -0.0044
PRO 961LEU 962 -0.0001
LEU 962ILE 963 0.0001
ILE 963PHE 964 -0.0003
PHE 964VAL 965 0.0013
VAL 965PHE 966 -0.0002
PHE 966LEU 967 -0.0003
LEU 967PHE 968 -0.0000
PHE 968SER 969 0.0025
SER 969VAL 970 0.0003
VAL 970VAL 971 0.0003
VAL 971ILE 972 0.0001
ILE 972GLY 973 0.0202
GLY 973SER 974 -0.0001
SER 974ILE 975 -0.0006
ILE 975TYR 976 0.0003
TYR 976LEU 977 -0.0023
LEU 977PHE 978 -0.0003
PHE 978LEU 979 0.0001
LEU 979ARG 980 0.0005
ARG 980LYS 981 0.0067
LYS 981ARG 982 0.0003
ARG 982ASN 953 0.0139
ASN 953ILE 954 0.0005
ILE 954ALA 955 -0.0003
ALA 955LYS 956 -0.0001
LYS 956ILE 957 0.0015
ILE 957ILE 958 -0.0001
ILE 958ILE 959 -0.0000
ILE 959GLY 960 0.0001
GLY 960PRO 961 -0.0064
PRO 961LEU 962 0.0000
LEU 962ILE 963 0.0002
ILE 963PHE 964 0.0002
PHE 964VAL 965 -0.0012
VAL 965PHE 966 -0.0001
PHE 966LEU 967 0.0002
LEU 967PHE 968 0.0005
PHE 968SER 969 0.0038
SER 969VAL 970 -0.0000
VAL 970VAL 971 -0.0001
VAL 971ILE 972 -0.0001
ILE 972GLY 973 0.0027
GLY 973SER 974 -0.0001
SER 974ILE 975 0.0002
ILE 975TYR 976 -0.0000
TYR 976LEU 977 -0.0016
LEU 977PHE 978 -0.0002
PHE 978LEU 979 -0.0002
LEU 979ARG 980 -0.0004
ARG 980LYS 981 0.0055
LYS 981ARG 982 -0.0000
ARG 982ASN 953 0.0092
ASN 953ILE 954 -0.0001
ILE 954ALA 955 0.0002
ALA 955LYS 956 -0.0001
LYS 956ILE 957 0.0051
ILE 957ILE 958 0.0001
ILE 958ILE 959 -0.0005
ILE 959GLY 960 -0.0001
GLY 960PRO 961 -0.0049
PRO 961LEU 962 0.0001
LEU 962ILE 963 0.0001
ILE 963PHE 964 0.0003
PHE 964VAL 965 -0.0012
VAL 965PHE 966 -0.0002
PHE 966LEU 967 0.0001
LEU 967PHE 968 0.0001
PHE 968SER 969 -0.0051
SER 969VAL 970 0.0002
VAL 970VAL 971 -0.0002
VAL 971ILE 972 -0.0001
ILE 972GLY 973 0.0021
GLY 973SER 974 0.0002
SER 974ILE 975 0.0002
ILE 975TYR 976 -0.0004
TYR 976LEU 977 -0.0011
LEU 977PHE 978 0.0001
PHE 978LEU 979 -0.0003
LEU 979ARG 980 0.0003
ARG 980LYS 981 0.0128
LYS 981ARG 982 0.0002

If you find results from this site helpful for your research, please cite one of our papers:

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.