Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A *

CA distance fluctuations for 2602051414582688829

--- normal mode 27 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
THR 24 0.31 ILE 1 -0.15 PRO 23

THR 24 0.34 VAL 2 -0.17 LYS 136

THR 24 0.31 GLY 3 -0.14 ASN 197

ARG 138 0.29 GLY 4 -0.14 ASN 197

ARG 138 0.32 THR 5 -0.15 LYS 140

ARG 138 0.34 ALA 6 -0.13 LYS 140

ARG 138 0.27 SER 7 -0.10 ASN 197

ARG 138 0.25 VAL 8 -0.11 ASN 197

ARG 138 0.27 ARG 9 -0.14 GLY 118

GLU 69 0.28 GLY 10 -0.20 GLU 198

GLU 69 0.20 GLU 11 -0.15 GLY 118

GLU 69 0.18 TRP 12 -0.15 GLY 118

GLU 69 0.23 PRO 13 -0.28 GLU 198

ASP 70 0.25 TRP 14 -0.30 GLU 198

ARG 138 0.18 GLN 15 -0.18 GLU 198

ARG 138 0.22 VAL 16 -0.18 GLU 198

ARG 138 0.27 THR 17 -0.14 GLU 198

LYS 140 0.31 LEU 18 -0.15 GLU 198

LYS 140 0.37 HIS 19 -0.17 GLU 69

LYS 140 0.38 THR 20 -0.32 GLU 69

LYS 140 0.40 THR 21 -0.51 GLU 69

LYS 140 0.35 SER 22 -0.53 GLU 69

THR 21 0.39 PRO 23 -0.43 GLY 48

LYS 140 0.89 THR 24 -0.83 GLU 69

LYS 140 0.38 GLN 25 -0.65 GLU 69

THR 24 0.59 ARG 26 -0.42 GLU 69

LYS 140 0.45 HIS 27 -0.21 PRO 23

LYS 140 0.42 LEU 28 -0.34 PRO 23

LYS 140 0.32 CYS 29 -0.28 PRO 23

LYS 140 0.21 GLY 30 -0.20 PRO 23

LYS 140 0.17 GLY 31 -0.17 PRO 23

ASP 70 0.22 SER 32 -0.23 GLU 198

ASP 70 0.32 ILE 33 -0.34 GLU 198

ASP 70 0.32 ILE 34 -0.40 GLU 198

ASP 70 0.42 GLY 35 -0.46 GLU 198

ASP 70 0.55 ASN 36 -0.45 GLU 198

ASP 70 0.51 GLN 37 -0.35 GLU 198

ASP 70 0.40 TRP 38 -0.32 GLU 198

ASP 70 0.32 ILE 39 -0.27 GLU 198

ASP 70 0.23 LEU 40 -0.22 GLU 198

LYS 140 0.20 THR 41 -0.18 PRO 23

LYS 140 0.23 ALA 42 -0.22 PRO 23

LYS 140 0.26 ALA 43 -0.21 PRO 23

LYS 86 0.35 HIS 44 -0.27 PRO 23

LYS 140 0.33 CYS 45 -0.30 PRO 23

LYS 140 0.31 PHE 46 -0.29 PRO 23

LYS 86 0.37 TYR 47 -0.32 PRO 23

LYS 86 0.29 GLY 48 -0.43 PRO 23

ASP 83 0.29 VAL 49 -0.42 PRO 23

SER 51 0.37 GLU 50 -0.41 PRO 23

GLU 50 0.37 SER 51 -0.33 THR 24

GLU 50 0.26 PRO 52 -0.46 LYS 53

ASP 70 0.36 LYS 53 -0.46 PRO 52

LYS 140 0.34 ILE 54 -0.44 THR 24

LYS 140 0.32 LEU 55 -0.24 THR 24

LYS 140 0.32 ARG 56 -0.19 GLU 198

ASP 70 0.34 VAL 57 -0.21 GLU 198

ASP 70 0.31 TYR 58 -0.20 GLU 198

ASP 70 0.36 SER 59 -0.24 GLU 198

GLU 69 0.39 GLY 60 -0.23 GLU 198

GLU 69 0.32 ILE 61 -0.15 GLU 198

ARG 138 0.33 LEU 62 -0.10 GLY 118

ARG 138 0.39 ASN 63 -0.23 ASP 70

ARG 138 0.40 GLN 64 -0.30 ASP 70

ARG 138 0.41 SER 65 -0.52 ASP 70

GLU 69 0.36 GLU 66 -0.36 ASP 70

ARG 138 0.36 ILE 67 -0.39 ASP 70

ARG 138 0.34 LYS 68 -0.82 ASP 70

THR 71 1.18 GLU 69 -0.83 THR 24

ASN 104 0.99 ASP 70 -0.82 LYS 68

GLU 69 1.18 THR 71 -0.16 GLU 198

ASP 70 0.94 SER 72 -0.21 GLU 198

ASP 70 0.69 PHE 73 -0.23 GLU 198

ASP 70 0.68 PHE 74 -0.26 GLU 198

ASP 70 0.56 GLY 75 -0.24 THR 24

ASP 70 0.42 VAL 76 -0.23 GLU 198

ASP 70 0.42 GLN 77 -0.24 GLU 198

ASP 70 0.33 GLU 78 -0.22 GLU 198

GLU 50 0.28 ILE 79 -0.22 LYS 53

ASP 70 0.24 ILE 80 -0.20 TYR 85

LYS 140 0.23 ILE 81 -0.23 TYR 85

GLY 164 0.23 HIS 82 -0.45 TYR 85

GLU 50 0.33 ASP 83 -0.19 LYS 86

GLY 164 0.36 GLN 84 -0.19 LYS 86

GLY 164 0.36 TYR 85 -0.45 HIS 82

MET 87 0.57 LYS 86 -0.25 HIS 82

LYS 86 0.57 MET 87 -0.15 PRO 23

LYS 86 0.27 ALA 88 -0.21 PRO 23

LYS 86 0.25 GLU 89 -0.19 PRO 23

GLY 164 0.41 SER 90 -0.15 PRO 23

GLY 164 0.33 GLY 91 -0.15 PRO 23

GLY 164 0.27 TYR 92 -0.22 TYR 85

LYS 140 0.22 ASP 93 -0.19 PRO 23

LYS 140 0.20 ILE 94 -0.23 TYR 85

LYS 140 0.22 ALA 95 -0.21 TYR 85

ASP 70 0.26 LEU 96 -0.22 GLU 198

ASP 70 0.32 LEU 97 -0.23 GLU 198

ASP 70 0.40 LYS 98 -0.27 GLU 198

ASP 70 0.52 LEU 99 -0.29 GLU 198

ASP 70 0.62 GLU 100 -0.28 GLU 198

ASP 70 0.81 THR 101 -0.35 GLU 198

ASP 70 0.79 THR 102 -0.41 GLU 198

ASP 70 0.82 VAL 103 -0.46 GLU 198

ASP 70 0.99 ASN 104 -0.59 GLU 198

ASP 70 0.70 TYR 105 -0.63 GLU 198

ASP 70 0.64 THR 106 -0.64 GLU 198

GLU 69 0.41 ASP 107 -0.53 GLU 198

GLU 69 0.41 SER 108 -0.36 GLU 198

ASP 70 0.40 GLN 109 -0.38 GLU 198

ASP 70 0.39 ARG 110 -0.52 GLU 198

ASP 70 0.34 PRO 111 -0.52 GLU 198

ASP 70 0.25 ILE 112 -0.48 GLU 198

ASP 70 0.22 SER 113 -0.57 GLU 198

ASP 70 0.20 LEU 114 -0.39 GLU 198

ASN 197 0.15 PRO 115 -0.32 GLU 198

GLY 164 0.17 SER 116 -0.45 LYS 117

HIS 169 0.32 LYS 117 -0.45 SER 116

ARG 120 0.69 GLY 118 -0.47 ASN 104

GLY 164 0.16 ASP 119 -0.48 ASN 121

GLY 118 0.69 ARG 120 -0.47 ASN 121

THR 154 0.49 ASN 121 -0.48 ASP 119

ILE 123 0.19 VAL 122 -0.23 ASN 104

GLU 198 0.35 ILE 123 -0.20 HIS 169

GLU 198 0.38 TYR 124 -0.15 ASN 104

GLU 198 0.49 THR 125 -0.17 ASN 197

GLU 198 0.52 ASP 126 -0.22 ASN 197

GLU 198 0.29 CYS 127 -0.13 PRO 23

GLU 198 0.19 TRP 128 -0.13 PRO 23

THR 24 0.16 VAL 129 -0.16 PRO 23

ARG 138 0.18 THR 130 -0.16 PRO 23

ARG 138 0.26 GLY 131 -0.17 PRO 23

ARG 138 0.39 TRP 132 -0.17 PRO 23

THR 24 0.38 GLY 133 -0.20 PRO 23

ARG 138 0.58 TYR 134 -0.15 PRO 23

ARG 138 0.57 ARG 135 -0.21 LYS 140

ARG 138 0.62 LYS 136 -0.28 ARG 215

THR 24 0.50 LEU 137 -0.29 GLY 164

ASP 139 1.20 ARG 138 -0.40 GLY 164

ARG 138 1.20 ASP 139 -0.18 ARG 215

THR 24 0.89 LYS 140 -0.21 ARG 135

THR 24 0.58 ILE 141 -0.21 ASP 70

ARG 138 0.57 GLN 142 -0.19 ASP 70

ARG 138 0.51 ASN 143 -0.29 ASP 70

ARG 138 0.43 THR 144 -0.19 ASP 70

ARG 138 0.34 LEU 145 -0.10 PRO 23

ARG 138 0.33 GLN 146 -0.12 PRO 23

ARG 138 0.22 LYS 147 -0.12 PRO 23

THR 24 0.20 ALA 148 -0.13 ASN 197

GLU 198 0.27 LYS 149 -0.16 ASN 197

GLU 198 0.25 ILE 150 -0.14 LYS 136

GLU 198 0.30 PRO 151 -0.13 PRO 23

ASN 121 0.33 LEU 152 -0.14 PRO 23

ASN 121 0.41 VAL 153 -0.15 PRO 23

ASN 121 0.49 THR 154 -0.15 GLU 156

GLY 118 0.40 ASN 155 -0.15 PRO 23

GLY 118 0.39 GLU 156 -0.15 THR 154

ASN 121 0.38 GLU 157 -0.16 LEU 137

ASN 121 0.32 CYS 158 -0.17 LEU 137

GLY 118 0.33 GLN 159 -0.18 ARG 138

GLY 118 0.29 LYS 160 -0.20 ARG 138

GLY 118 0.27 ARG 161 -0.23 ARG 138

GLY 118 0.26 TYR 162 -0.24 ARG 138

GLY 118 0.25 ARG 163 -0.25 ARG 138

HIS 165 0.75 GLY 164 -0.40 ARG 138

GLY 164 0.75 HIS 165 -0.22 ARG 138

GLY 164 0.65 LYS 166 -0.17 PRO 23

GLY 164 0.37 ILE 167 -0.17 PRO 23

GLY 164 0.36 THR 168 -0.15 PRO 23

GLY 118 0.39 HIS 169 -0.20 ILE 123

GLY 164 0.29 LYS 170 -0.16 ILE 123

GLY 118 0.29 MET 171 -0.16 PRO 23

GLY 118 0.29 ILE 172 -0.16 PRO 23

ASN 121 0.28 CYS 173 -0.17 PRO 23

ASN 121 0.26 ALA 174 -0.16 PRO 23

ASN 121 0.24 GLY 175 -0.17 LYS 136

ASN 121 0.23 TYR 176 -0.17 GLY 179

ASN 121 0.29 ARG 177 -0.22 GLN 214

ARG 215 0.28 GLU 178 -0.31 GLY 179

THR 24 0.27 GLY 179 -0.31 GLU 178

THR 24 0.30 GLY 180 -0.27 GLU 178

THR 24 0.27 LYS 181 -0.16 LYS 136

THR 24 0.27 ASP 182 -0.18 LYS 136

THR 24 0.26 ALA 183 -0.20 PRO 23

THR 24 0.33 CYS 184 -0.22 PRO 23

THR 24 0.39 LYS 185 -0.28 PRO 23

THR 24 0.36 GLY 186 -0.27 PRO 23

THR 24 0.25 ASP 187 -0.24 PRO 23

LYS 86 0.24 SER 188 -0.27 PRO 23

LYS 140 0.20 GLY 189 -0.24 PRO 23

LYS 140 0.12 GLY 190 -0.20 PRO 23

ASP 70 0.10 PRO 191 -0.17 PRO 23

THR 24 0.11 LEU 192 -0.16 PRO 23

ASP 70 0.11 SER 193 -0.14 ASN 104

GLU 198 0.16 CYS 194 -0.17 ASN 104

GLU 198 0.28 LYS 195 -0.21 THR 106

GLU 198 0.26 HIS 196 -0.23 THR 106

PRO 115 0.15 ASN 197 -0.25 THR 106

ASP 126 0.52 GLU 198 -0.76 VAL 199

ASP 70 0.16 VAL 199 -0.76 GLU 198

ASP 70 0.15 TRP 200 -0.34 GLU 198

ASP 70 0.15 HIS 201 -0.28 GLU 198

ASP 70 0.15 LEU 202 -0.19 ASN 104

ASP 70 0.12 VAL 203 -0.17 ASN 104

ASP 70 0.11 GLY 204 -0.16 PRO 23

LYS 140 0.11 ILE 205 -0.19 PRO 23

THR 24 0.15 THR 206 -0.22 PRO 23

LYS 140 0.18 SER 207 -0.24 PRO 23

LYS 86 0.26 TRP 208 -0.25 PRO 23

LYS 86 0.26 ALA 209 -0.22 PRO 23

LYS 86 0.29 GLU 210 -0.32 GLY 164

THR 24 0.33 GLY 211 -0.30 ARG 138

THR 24 0.33 CYS 212 -0.24 LEU 137

THR 24 0.31 ALA 213 -0.25 LYS 136

THR 24 0.31 GLN 214 -0.51 ARG 215

GLU 178 0.28 ARG 215 -0.51 GLN 214

ASN 121 0.25 GLU 216 -0.23 GLN 214

THR 24 0.23 ARG 217 -0.21 LEU 137

ASN 121 0.23 PRO 218 -0.19 LEU 137

THR 24 0.20 GLY 219 -0.20 PRO 23

GLY 118 0.20 VAL 220 -0.20 PRO 23

GLY 118 0.17 TYR 221 -0.19 PRO 23

GLY 118 0.16 THR 222 -0.18 PRO 23

GLY 118 0.21 ASN 223 -0.14 PRO 23

ASP 70 0.15 VAL 224 -0.17 TYR 85

LYS 117 0.19 VAL 225 -0.22 ASN 104

LYS 117 0.26 GLU 226 -0.18 GLN 84

GLY 164 0.20 TYR 227 -0.23 TYR 85

ASP 70 0.19 VAL 228 -0.27 GLU 198

GLY 164 0.22 ASP 229 -0.28 GLU 198

GLY 164 0.22 TRP 230 -0.25 GLU 198

ASP 70 0.24 ILE 231 -0.27 GLU 198

ASP 70 0.25 LEU 232 -0.32 GLU 198

ASP 70 0.24 GLU 233 -0.30 GLU 198

ASP 70 0.27 LYS 234 -0.28 GLU 198

ASP 70 0.33 THR 235 -0.32 GLU 198

ASP 70 0.31 GLN 236 -0.35 GLU 198

ASP 70 0.34 ALA 237 -0.29 GLU 198

ASP 70 0.41 VAL 238 -0.25 GLU 198

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A ***

CA distance fluctuations for 2602051414582688829

--- normal mode 27 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A *