Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G226A *

CA distance fluctuations for 2602051428002699079

--- normal mode 28 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
PRO 23 0.21 ILE 1 -0.49 THR 24

GLY 164 0.22 VAL 2 -0.50 THR 24

GLY 164 0.21 GLY 3 -0.45 THR 24

GLY 164 0.17 GLY 4 -0.41 THR 24

GLY 164 0.14 THR 5 -0.38 THR 24

GLY 164 0.12 ALA 6 -0.36 THR 24

GLY 164 0.10 SER 7 -0.29 THR 24

GLY 164 0.08 VAL 8 -0.22 THR 24

GLY 164 0.07 ARG 9 -0.19 GLU 178

GLU 216 0.08 GLY 10 -0.17 ASP 70

GLU 216 0.10 GLU 11 -0.19 GLU 178

GLU 216 0.10 TRP 12 -0.18 GLU 178

GLU 216 0.08 PRO 13 -0.15 GLU 178

GLU 216 0.08 TRP 14 -0.14 GLU 178

PRO 23 0.09 GLN 15 -0.15 GLU 178

PRO 23 0.07 VAL 16 -0.14 GLU 178

PRO 23 0.10 THR 17 -0.19 THR 24

PRO 23 0.13 LEU 18 -0.11 GLU 178

ASP 70 0.09 HIS 19 -0.11 LYS 86

ASP 70 0.15 THR 20 -0.12 LYS 86

THR 24 0.53 THR 21 -0.36 PRO 23

THR 24 0.48 SER 22 -0.13 LYS 86

VAL 49 0.52 PRO 23 -0.38 GLU 69

ILE 54 0.67 THR 24 -0.91 LYS 140

ASP 70 0.20 GLN 25 -0.26 PRO 23

GLU 69 0.17 ARG 26 -0.60 THR 24

PRO 23 0.24 HIS 27 -0.51 THR 24

PRO 23 0.41 LEU 28 -0.39 THR 24

PRO 23 0.32 CYS 29 -0.31 THR 24

PRO 23 0.22 GLY 30 -0.25 THR 24

PRO 23 0.16 GLY 31 -0.12 GLU 178

PRO 23 0.12 SER 32 -0.12 GLU 178

GLU 216 0.07 ILE 33 -0.11 GLU 178

ASN 104 0.09 ILE 34 -0.17 ALA 237

ASN 104 0.11 GLY 35 -0.20 ALA 237

ASN 104 0.14 ASN 36 -0.15 ALA 237

THR 24 0.18 GLN 37 -0.12 GLU 69

THR 24 0.12 TRP 38 -0.12 ARG 163

PRO 23 0.08 ILE 39 -0.11 ARG 163

PRO 23 0.14 LEU 40 -0.13 ARG 163

PRO 23 0.21 THR 41 -0.13 ARG 163

PRO 23 0.29 ALA 42 -0.16 ARG 163

PRO 23 0.30 ALA 43 -0.19 ARG 163

PRO 23 0.39 HIS 44 -0.24 LYS 86

PRO 23 0.42 CYS 45 -0.19 THR 24

PRO 23 0.40 PHE 46 -0.15 LYS 86

PRO 23 0.46 TYR 47 -0.25 LEU 137

GLU 50 0.68 GLY 48 -0.25 LEU 137

GLY 48 0.60 VAL 49 -0.19 ASP 83

GLY 48 0.68 GLU 50 -0.28 ASP 83

THR 24 0.51 SER 51 -0.12 GLU 50

THR 24 0.47 PRO 52 -0.12 GLU 50

THR 24 0.67 LYS 53 -0.21 GLU 69

THR 24 0.67 ILE 54 -0.14 PRO 23

THR 24 0.37 LEU 55 -0.10 GLU 69

THR 24 0.28 ARG 56 -0.15 GLU 69

THR 24 0.12 VAL 57 -0.11 GLU 69

ARG 9 0.02 TYR 58 -0.12 GLU 178

GLU 216 0.03 SER 59 -0.13 GLU 178

GLU 216 0.04 GLY 60 -0.19 ASP 70

GLY 164 0.05 ILE 61 -0.21 ASP 70

GLU 69 0.07 LEU 62 -0.25 THR 24

GLU 69 0.13 ASN 63 -0.33 THR 24

GLU 69 0.17 GLN 64 -0.39 THR 24

GLU 69 0.24 SER 65 -0.37 THR 24

GLU 69 0.18 GLU 66 -0.36 ASP 70

GLU 69 0.20 ILE 67 -0.32 ASP 70

GLU 69 0.66 LYS 68 -0.34 ASP 70

LYS 68 0.66 GLU 69 -0.38 PRO 23

THR 24 0.46 ASP 70 -0.42 THR 71

THR 24 0.14 THR 71 -0.42 ASP 70

THR 24 0.21 SER 72 -0.37 GLU 69

THR 24 0.23 PHE 73 -0.27 GLU 69

THR 24 0.28 PHE 74 -0.22 GLU 69

THR 24 0.43 GLY 75 -0.20 GLU 69

THR 24 0.37 VAL 76 -0.14 GLU 69

THR 24 0.42 GLN 77 -0.13 GLU 50

THR 24 0.33 GLU 78 -0.20 GLU 50

THR 24 0.22 ILE 79 -0.24 GLU 50

ALA 237 0.21 ILE 80 -0.23 GLU 50

ALA 237 0.20 ILE 81 -0.23 GLU 50

TYR 85 0.28 HIS 82 -0.25 ARG 163

ALA 237 0.29 ASP 83 -0.28 ARG 163

ALA 237 0.21 GLN 84 -0.36 GLY 164

HIS 82 0.28 TYR 85 -0.34 ARG 163

ALA 237 0.21 LYS 86 -0.54 MET 87

PRO 23 0.33 MET 87 -0.54 LYS 86

PRO 23 0.34 ALA 88 -0.27 ARG 163

PRO 23 0.34 GLU 89 -0.37 ARG 163

PRO 23 0.30 SER 90 -0.42 ARG 163

PRO 23 0.27 GLY 91 -0.37 ARG 163

PRO 23 0.24 TYR 92 -0.30 ARG 163

PRO 23 0.28 ASP 93 -0.25 ARG 163

PRO 23 0.23 ILE 94 -0.21 ARG 163

PRO 23 0.20 ALA 95 -0.18 ARG 163

PRO 23 0.14 LEU 96 -0.16 ARG 163

THR 24 0.16 LEU 97 -0.13 GLU 50

THR 24 0.24 LYS 98 -0.13 GLU 50

THR 24 0.27 LEU 99 -0.14 GLU 69

THR 24 0.37 GLU 100 -0.17 GLU 69

THR 24 0.29 THR 101 -0.20 GLU 69

THR 24 0.20 THR 102 -0.18 GLU 69

THR 24 0.12 VAL 103 -0.18 GLU 69

ASN 36 0.14 ASN 104 -0.21 GLU 69

ASN 197 0.09 TYR 105 -0.15 ASP 70

ARG 110 0.10 THR 106 -0.21 ASP 70

GLU 216 0.09 ASP 107 -0.18 ASP 70

GLU 216 0.07 SER 108 -0.20 ASP 70

GLU 216 0.06 GLN 109 -0.14 ASP 70

THR 106 0.10 ARG 110 -0.13 ALA 237

ASN 104 0.11 PRO 111 -0.15 ALA 237

GLU 216 0.11 ILE 112 -0.15 ALA 237

GLU 216 0.12 SER 113 -0.19 ALA 237

GLU 216 0.12 LEU 114 -0.18 ALA 237

GLU 216 0.15 PRO 115 -0.17 ALA 237

GLU 216 0.15 SER 116 -0.23 GLY 118

THR 154 0.21 LYS 117 -0.20 ALA 237

ARG 120 0.36 GLY 118 -0.23 SER 116

GLU 216 0.19 ASP 119 -0.15 ALA 237

GLY 118 0.36 ARG 120 -0.13 ASN 121

THR 154 0.27 ASN 121 -0.13 ARG 120

GLU 216 0.23 VAL 122 -0.12 ALA 237

GLU 216 0.25 ILE 123 -0.15 THR 24

GLU 216 0.25 TYR 124 -0.16 THR 24

GLU 216 0.26 THR 125 -0.19 THR 24

GLU 216 0.23 ASP 126 -0.22 GLU 178

GLU 216 0.23 CYS 127 -0.22 GLU 178

GLU 216 0.18 TRP 128 -0.25 THR 24

PRO 23 0.18 VAL 129 -0.30 THR 24

PRO 23 0.17 THR 130 -0.32 THR 24

PRO 23 0.19 GLY 131 -0.38 THR 24

PRO 23 0.20 TRP 132 -0.50 THR 24

PRO 23 0.27 GLY 133 -0.60 THR 24

PRO 23 0.28 TYR 134 -0.67 THR 24

PRO 23 0.21 ARG 135 -0.61 THR 24

GLY 164 0.23 LYS 136 -0.64 THR 24

GLY 164 0.25 LEU 137 -0.68 THR 24

PRO 23 0.26 ARG 138 -0.78 THR 24

PRO 23 0.27 ASP 139 -0.81 THR 24

PRO 23 0.30 LYS 140 -0.91 THR 24

PRO 23 0.26 ILE 141 -0.80 THR 24

PRO 23 0.17 GLN 142 -0.64 THR 24

GLU 69 0.15 ASN 143 -0.54 THR 24

GLU 69 0.11 THR 144 -0.42 THR 24

PRO 23 0.11 LEU 145 -0.37 THR 24

PRO 23 0.14 GLN 146 -0.40 THR 24

PRO 23 0.14 LYS 147 -0.34 THR 24

PRO 23 0.15 ALA 148 -0.34 THR 24

GLU 216 0.22 LYS 149 -0.34 GLU 178

GLU 216 0.29 ILE 150 -0.35 GLU 178

GLU 216 0.35 PRO 151 -0.29 GLU 178

GLU 216 0.33 LEU 152 -0.23 THR 24

GLU 216 0.29 VAL 153 -0.26 GLU 156

GLY 118 0.27 THR 154 -0.39 GLU 156

HIS 169 0.22 ASN 155 -0.24 THR 154

LYS 160 0.30 GLU 156 -0.39 THR 154

LYS 160 0.30 GLU 157 -0.33 GLU 156

ARG 161 0.24 CYS 158 -0.25 THR 24

TYR 162 0.31 GLN 159 -0.26 ARG 163

GLU 157 0.30 LYS 160 -0.29 THR 24

GLU 178 0.29 ARG 161 -0.31 THR 24

GLY 164 0.32 TYR 162 -0.29 THR 24

ARG 215 0.49 ARG 163 -0.85 HIS 165

ARG 215 0.60 GLY 164 -0.38 SER 90

PRO 23 0.33 HIS 165 -0.85 ARG 163

PRO 23 0.30 LYS 166 -0.57 ARG 163

PRO 23 0.26 ILE 167 -0.48 ARG 163

PRO 23 0.24 THR 168 -0.39 ARG 163

GLU 156 0.23 HIS 169 -0.29 ARG 163

PRO 23 0.21 LYS 170 -0.30 ARG 163

PRO 23 0.24 MET 171 -0.29 ARG 163

PRO 23 0.22 ILE 172 -0.19 ARG 163

PRO 23 0.22 CYS 173 -0.24 THR 24

GLU 216 0.29 ALA 174 -0.27 THR 24

GLU 216 0.46 GLY 175 -0.33 THR 24

GLU 216 0.64 TYR 176 -0.43 GLU 178

GLU 216 0.70 ARG 177 -0.45 ARG 215

GLU 216 0.62 GLU 178 -0.44 LYS 181

GLY 164 0.35 GLY 179 -0.41 THR 24

GLY 164 0.31 GLY 180 -0.45 THR 24

GLY 164 0.24 LYS 181 -0.44 GLU 178

GLY 164 0.22 ASP 182 -0.41 THR 24

PRO 23 0.25 ALA 183 -0.42 THR 24

PRO 23 0.30 CYS 184 -0.52 THR 24

PRO 23 0.39 LYS 185 -0.59 THR 24

PRO 23 0.36 GLY 186 -0.57 THR 24

PRO 23 0.29 ASP 187 -0.42 THR 24

PRO 23 0.33 SER 188 -0.34 THR 24

PRO 23 0.27 GLY 189 -0.21 THR 24

PRO 23 0.22 GLY 190 -0.24 THR 24

PRO 23 0.18 PRO 191 -0.20 THR 24

PRO 23 0.18 LEU 192 -0.21 THR 24

GLU 216 0.16 SER 193 -0.18 THR 24

GLU 216 0.19 CYS 194 -0.17 GLU 178

GLU 216 0.19 LYS 195 -0.16 GLU 178

GLU 216 0.19 HIS 196 -0.13 GLU 178

GLU 216 0.15 ASN 197 -0.15 GLU 178

GLU 216 0.16 GLU 198 -0.13 GLU 178

GLU 216 0.16 VAL 199 -0.14 ALA 237

GLU 216 0.16 TRP 200 -0.14 GLU 178

GLU 216 0.15 HIS 201 -0.14 ALA 237

PRO 23 0.14 LEU 202 -0.12 GLU 178

PRO 23 0.16 VAL 203 -0.14 THR 24

PRO 23 0.20 GLY 204 -0.16 THR 24

PRO 23 0.23 ILE 205 -0.18 THR 24

PRO 23 0.27 THR 206 -0.27 THR 24

PRO 23 0.32 SER 207 -0.26 THR 24

PRO 23 0.35 TRP 208 -0.31 THR 24

PRO 23 0.32 GLY 209 -0.35 THR 24

GLY 164 0.42 GLU 210 -0.37 THR 24

GLY 164 0.38 GLY 211 -0.46 THR 24

GLY 164 0.31 CYS 212 -0.48 THR 24

GLY 164 0.31 ALA 213 -0.45 THR 24

GLY 164 0.43 GLN 214 -0.42 THR 24

GLY 164 0.60 ARG 215 -0.45 ARG 177

ARG 177 0.70 GLU 216 -0.37 THR 24

GLY 164 0.39 ARG 217 -0.36 THR 24

GLY 175 0.24 PRO 218 -0.34 THR 24

PRO 23 0.26 ALA 219 -0.33 THR 24

PRO 23 0.27 VAL 220 -0.26 THR 24

PRO 23 0.25 TYR 221 -0.22 THR 24

PRO 23 0.24 THR 222 -0.22 ARG 163

PRO 23 0.20 ASN 223 -0.21 ARG 163

PRO 23 0.17 VAL 224 -0.18 ARG 163

PRO 23 0.15 VAL 225 -0.17 ARG 163

PRO 23 0.17 GLU 226 -0.23 ARG 163

TYR 85 0.16 TYR 227 -0.22 ARG 163

TYR 85 0.13 VAL 228 -0.19 ARG 163

TYR 85 0.11 ASP 229 -0.21 ARG 163

TYR 85 0.15 TRP 230 -0.22 ARG 163

TYR 85 0.14 ILE 231 -0.18 ARG 163

TYR 85 0.12 LEU 232 -0.35 ALA 237

GLN 236 0.21 GLU 233 -0.20 ARG 163

THR 235 0.22 LYS 234 -0.18 ARG 163

LYS 234 0.22 THR 235 -0.33 ALA 237

GLU 233 0.21 GLN 236 -0.87 ALA 237

ASP 83 0.29 ALA 237 -0.87 GLN 236

THR 24 0.21 VAL 238 -0.16 GLU 50

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G226A ***

CA distance fluctuations for 2602051428002699079

--- normal mode 28 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G226A *