Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *

CA distance fluctuations for 2602060425492843205

--- normal mode 27 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
THR 24 0.42 ILE 1 -0.43 PRO 23

THR 24 0.42 VAL 2 -0.43 PRO 23

THR 24 0.39 GLY 3 -0.35 PRO 23

THR 24 0.37 GLY 4 -0.33 ARG 138

THR 24 0.35 THR 5 -0.36 ARG 138

THR 24 0.34 ALA 6 -0.37 ARG 138

THR 24 0.26 SER 7 -0.32 ARG 138

THR 24 0.21 VAL 8 -0.29 ARG 138

THR 24 0.17 ARG 9 -0.27 ARG 138

GLY 118 0.15 GLY 10 -0.21 ARG 138

THR 24 0.15 GLU 11 -0.22 ARG 138

ARG 177 0.15 TRP 12 -0.19 ARG 138

GLY 118 0.15 PRO 13 -0.15 ARG 138

GLY 118 0.16 TRP 14 -0.11 ARG 138

ARG 177 0.16 GLN 15 -0.14 PRO 23

ARG 177 0.15 VAL 16 -0.10 PRO 23

THR 24 0.19 THR 17 -0.14 PRO 23

LEU 137 0.17 LEU 18 -0.14 PRO 23

LEU 137 0.21 HIS 19 -0.13 ASN 104

LEU 137 0.22 THR 20 -0.15 THR 24

PRO 23 0.35 THR 21 -0.59 THR 24

LEU 137 0.21 SER 22 -0.79 THR 24

GLU 69 0.73 PRO 23 -0.73 GLY 48

LYS 140 0.75 THR 24 -0.79 SER 22

THR 24 0.24 GLN 25 -0.16 ASN 104

THR 24 0.67 ARG 26 -0.19 PRO 23

THR 24 0.51 HIS 27 -0.32 PRO 23

THR 24 0.31 LEU 28 -0.50 PRO 23

THR 24 0.25 CYS 29 -0.44 PRO 23

THR 24 0.22 GLY 30 -0.31 PRO 23

ARG 177 0.16 GLY 31 -0.22 PRO 23

ARG 177 0.15 SER 32 -0.15 PRO 23

GLY 118 0.18 ILE 33 -0.07 TRP 38

GLY 118 0.25 ILE 34 -0.06 PRO 23

ASN 104 0.33 GLY 35 -0.11 GLN 37

ASN 104 0.44 ASN 36 -0.10 THR 24

THR 102 0.28 GLN 37 -0.13 THR 24

VAL 103 0.20 TRP 38 -0.09 THR 24

VAL 103 0.15 ILE 39 -0.08 THR 235

THR 154 0.17 LEU 40 -0.17 PRO 23

SER 207 0.18 THR 41 -0.27 PRO 23

SER 207 0.23 ALA 42 -0.40 PRO 23

LEU 137 0.15 ALA 43 -0.41 PRO 23

LEU 137 0.18 HIS 44 -0.58 PRO 23

LEU 137 0.22 CYS 45 -0.55 PRO 23

LEU 137 0.20 PHE 46 -0.47 PRO 23

LEU 137 0.13 TYR 47 -0.69 PRO 23

VAL 49 0.32 GLY 48 -0.73 PRO 23

GLY 48 0.32 VAL 49 -0.40 PRO 23

SER 51 0.33 GLU 50 -0.52 THR 24

GLU 50 0.33 SER 51 -0.51 THR 24

GLU 50 0.21 PRO 52 -0.44 THR 24

PRO 23 0.46 LYS 53 -0.57 THR 24

PRO 23 0.34 ILE 54 -0.67 THR 24

GLU 69 0.21 LEU 55 -0.36 THR 24

PRO 23 0.24 ARG 56 -0.22 THR 24

GLU 69 0.15 VAL 57 -0.13 ASN 104

ARG 177 0.14 TYR 58 -0.20 ASN 104

GLY 118 0.14 SER 59 -0.17 ASN 104

GLY 118 0.14 GLY 60 -0.23 SER 108

THR 24 0.17 ILE 61 -0.19 ARG 138

THR 24 0.24 LEU 62 -0.26 ARG 138

THR 24 0.33 ASN 63 -0.28 ARG 138

THR 24 0.41 GLN 64 -0.21 ARG 138

THR 24 0.38 SER 65 -0.25 GLU 69

THR 24 0.25 GLU 66 -0.21 GLU 69

THR 24 0.34 ILE 67 -0.30 ASN 104

PRO 23 0.54 LYS 68 -0.62 THR 71

PRO 23 0.73 GLU 69 -0.45 LYS 68

PRO 23 0.56 ASP 70 -0.32 LYS 68

PRO 23 0.42 THR 71 -0.62 LYS 68

PRO 23 0.38 SER 72 -0.32 LYS 68

PRO 23 0.33 PHE 73 -0.23 ASN 104

PRO 23 0.28 PHE 74 -0.21 THR 24

PRO 23 0.36 GLY 75 -0.33 THR 24

GLU 69 0.22 VAL 76 -0.31 THR 24

PRO 23 0.23 GLN 77 -0.35 THR 24

ILE 79 0.24 GLU 78 -0.33 ALA 237

GLU 78 0.24 ILE 79 -0.28 ALA 237

TYR 85 0.18 ILE 80 -0.31 ALA 237

GLU 78 0.18 ILE 81 -0.26 PRO 23

TYR 85 0.17 HIS 82 -0.28 PRO 23

GLU 78 0.16 ASP 83 -0.29 PRO 23

GLU 78 0.14 GLN 84 -0.34 PRO 23

GLU 78 0.18 TYR 85 -0.40 PRO 23

GLU 78 0.17 LYS 86 -0.49 PRO 23

GLU 78 0.15 MET 87 -0.55 PRO 23

HIS 44 0.17 ALA 88 -0.53 PRO 23

THR 24 0.17 GLU 89 -0.50 PRO 23

LYS 166 0.14 SER 90 -0.44 PRO 23

GLN 159 0.14 GLY 91 -0.41 PRO 23

GLU 78 0.14 TYR 92 -0.36 PRO 23

GLN 159 0.15 ASP 93 -0.41 PRO 23

ALA 95 0.20 ILE 94 -0.32 PRO 23

ILE 94 0.20 ALA 95 -0.25 PRO 23

ASN 155 0.14 LEU 96 -0.13 PRO 23

GLN 159 0.14 LEU 97 -0.15 THR 24

GLU 50 0.16 LYS 98 -0.20 THR 24

PRO 23 0.18 LEU 99 -0.21 THR 24

PRO 23 0.31 GLU 100 -0.28 THR 24

PRO 23 0.29 THR 101 -0.23 THR 24

GLN 37 0.28 THR 102 -0.17 THR 24

ASN 36 0.43 VAL 103 -0.21 LYS 68

ASN 36 0.44 ASN 104 -0.33 LYS 68

GLY 118 0.36 TYR 105 -0.26 LYS 68

GLY 118 0.34 THR 106 -0.30 LYS 68

GLY 118 0.31 ASP 107 -0.24 LYS 68

GLY 118 0.22 SER 108 -0.25 ILE 67

GLY 118 0.22 GLN 109 -0.17 TYR 105

GLY 118 0.28 ARG 110 -0.13 LYS 68

GLY 118 0.28 PRO 111 -0.09 ARG 138

GLY 118 0.25 ILE 112 -0.10 PRO 23

GLU 198 0.35 SER 113 -0.10 PRO 23

GLU 198 0.28 LEU 114 -0.14 PRO 23

GLU 198 0.29 PRO 115 -0.16 PRO 23

GLY 118 0.39 SER 116 -0.13 PRO 23

ALA 237 0.41 LYS 117 -0.25 ARG 120

GLU 198 0.45 GLY 118 -0.67 ARG 120

ASN 121 0.47 ASP 119 -0.19 GLY 118

ASN 121 0.49 ARG 120 -0.67 GLY 118

ARG 120 0.49 ASN 121 -0.43 LEU 152

ALA 237 0.26 VAL 122 -0.34 ILE 123

ALA 237 0.21 ILE 123 -0.41 ASN 121

THR 154 0.20 TYR 124 -0.26 ASN 121

LYS 160 0.16 THR 125 -0.34 ASN 121

ARG 177 0.15 ASP 126 -0.39 GLU 198

ARG 177 0.19 CYS 127 -0.27 PRO 23

ARG 177 0.21 TRP 128 -0.28 PRO 23

THR 24 0.25 VAL 129 -0.33 PRO 23

THR 24 0.28 THR 130 -0.31 PRO 23

THR 24 0.33 GLY 131 -0.35 PRO 23

THR 24 0.44 TRP 132 -0.38 PRO 23

THR 24 0.52 GLY 133 -0.51 PRO 23

THR 24 0.56 TYR 134 -0.57 PRO 23

THR 24 0.52 ARG 135 -0.55 ARG 138

THR 24 0.54 LYS 136 -0.51 ARG 138

THR 24 0.59 LEU 137 -0.53 PRO 23

THR 24 0.57 ARG 138 -0.87 ASP 139

THR 24 0.65 ASP 139 -0.87 ARG 138

THR 24 0.75 LYS 140 -0.63 PRO 23

THR 24 0.70 ILE 141 -0.52 PRO 23

THR 24 0.58 GLN 142 -0.41 ARG 138

THR 24 0.49 ASN 143 -0.36 ARG 138

THR 24 0.39 THR 144 -0.36 ARG 138

THR 24 0.35 LEU 145 -0.31 ARG 138

THR 24 0.35 GLN 146 -0.34 ARG 138

THR 24 0.30 LYS 147 -0.29 ARG 138

THR 24 0.29 ALA 148 -0.31 PRO 23

THR 24 0.24 LYS 149 -0.32 GLU 198

ARG 177 0.28 ILE 150 -0.32 PRO 23

THR 24 0.22 PRO 151 -0.38 ASN 121

THR 24 0.19 LEU 152 -0.43 ASN 121

THR 24 0.20 VAL 153 -0.35 ASN 121

ASN 223 0.23 THR 154 -0.33 ASN 121

HIS 169 0.23 ASN 155 -0.32 PRO 23

LYS 160 0.25 GLU 156 -0.33 GLU 157

LYS 160 0.32 GLU 157 -0.33 PRO 23

THR 24 0.21 CYS 158 -0.36 PRO 23

THR 24 0.20 GLN 159 -0.35 PRO 23

GLU 157 0.32 LYS 160 -0.39 PRO 23

THR 24 0.22 ARG 161 -0.42 PRO 23

THR 24 0.20 TYR 162 -0.45 PRO 23

ARG 215 0.24 ARG 163 -0.41 PRO 23

ARG 215 0.25 GLY 164 -0.42 PRO 23

THR 24 0.20 HIS 165 -0.41 PRO 23

THR 24 0.17 LYS 166 -0.36 PRO 23

GLN 159 0.18 ILE 167 -0.37 PRO 23

GLU 156 0.13 THR 168 -0.33 PRO 23

ASN 155 0.23 HIS 169 -0.34 GLY 118

ASN 155 0.18 LYS 170 -0.32 PRO 23

ASN 155 0.19 MET 171 -0.35 PRO 23

THR 154 0.22 ILE 172 -0.34 PRO 23

THR 24 0.21 CYS 173 -0.36 PRO 23

THR 24 0.23 ALA 174 -0.35 PRO 23

ARG 177 0.32 GLY 175 -0.36 PRO 23

ARG 177 0.68 TYR 176 -0.38 GLU 178

TYR 176 0.68 ARG 177 -0.32 PRO 23

GLU 216 0.44 GLU 178 -0.38 TYR 176

THR 24 0.33 GLY 179 -0.38 PRO 23

THR 24 0.37 GLY 180 -0.37 PRO 23

THR 24 0.35 LYS 181 -0.37 PRO 23

THR 24 0.35 ASP 182 -0.42 PRO 23

THR 24 0.36 ALA 183 -0.47 PRO 23

THR 24 0.43 CYS 184 -0.57 PRO 23

THR 24 0.48 LYS 185 -0.69 PRO 23

THR 24 0.48 GLY 186 -0.60 PRO 23

THR 24 0.36 ASP 187 -0.48 PRO 23

THR 24 0.27 SER 188 -0.52 PRO 23

SER 207 0.19 GLY 189 -0.39 PRO 23

THR 24 0.21 GLY 190 -0.33 PRO 23

THR 24 0.17 PRO 191 -0.28 PRO 23

ARG 177 0.19 LEU 192 -0.30 PRO 23

ARG 177 0.18 SER 193 -0.24 PRO 23

ARG 177 0.16 CYS 194 -0.23 PRO 23

ALA 237 0.14 LYS 195 -0.25 GLU 198

ALA 237 0.17 HIS 196 -0.18 PRO 23

GLY 118 0.30 ASN 197 -0.19 LYS 195

VAL 199 0.69 GLU 198 -0.39 ASP 126

GLU 198 0.69 VAL 199 -0.17 ASN 197

ASP 107 0.20 TRP 200 -0.15 PRO 23

GLU 198 0.20 HIS 201 -0.17 PRO 23

THR 154 0.19 LEU 202 -0.20 PRO 23

THR 154 0.21 VAL 203 -0.25 PRO 23

THR 154 0.20 GLY 204 -0.31 PRO 23

CYS 173 0.17 ILE 205 -0.34 PRO 23

THR 24 0.22 THR 206 -0.43 PRO 23

ALA 42 0.23 SER 207 -0.48 PRO 23

THR 24 0.26 TRP 208 -0.55 PRO 23

THR 24 0.30 GLY 209 -0.53 PRO 23

THR 24 0.32 GLU 210 -0.55 PRO 23

THR 24 0.39 GLY 211 -0.59 PRO 23

THR 24 0.41 CYS 212 -0.53 PRO 23

THR 24 0.37 ALA 213 -0.45 PRO 23

THR 24 0.35 GLN 214 -0.46 PRO 23

THR 24 0.32 ARG 215 -0.39 PRO 23

GLU 178 0.44 GLU 216 -0.41 PRO 23

THR 24 0.29 ARG 217 -0.45 PRO 23

THR 24 0.27 PRO 218 -0.42 PRO 23

THR 24 0.28 GLY 219 -0.44 PRO 23

THR 24 0.23 VAL 220 -0.43 PRO 23

VAL 220 0.18 TYR 221 -0.39 PRO 23

ASN 155 0.17 THR 222 -0.35 PRO 23

ASN 155 0.23 ASN 223 -0.31 PRO 23

THR 154 0.19 VAL 224 -0.25 PRO 23

ALA 237 0.23 VAL 225 -0.22 PRO 23

ALA 237 0.20 GLU 226 -0.24 PRO 23

ASN 121 0.19 TYR 227 -0.22 PRO 23

ALA 237 0.30 VAL 228 -0.16 PRO 23

ALA 237 0.33 ASP 229 -0.15 PRO 23

ASN 121 0.21 TRP 230 -0.17 PRO 23

ALA 237 0.25 ILE 231 -0.14 PRO 23

ALA 237 0.53 LEU 232 -0.08 PRO 23

ALA 237 0.39 GLU 233 -0.12 THR 24

ASN 104 0.22 LYS 234 -0.22 GLN 236

ALA 237 0.42 THR 235 -0.16 THR 24

ALA 237 0.95 GLN 236 -0.22 LYS 234

GLN 236 0.95 ALA 237 -0.33 GLU 78

GLY 118 0.24 VAL 238 -0.23 THR 24

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa WT ***

CA distance fluctuations for 2602060425492843205

--- normal mode 27 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *