Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *

CA distance fluctuations for 2602060425492843205

--- normal mode 30 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ILE 54 0.20 ILE 1 -0.70 THR 24

GLY 180 0.21 VAL 2 -0.70 THR 24

ILE 54 0.17 GLY 3 -0.65 THR 24

ILE 54 0.16 GLY 4 -0.64 THR 24

ILE 54 0.13 THR 5 -0.66 THR 24

LYS 53 0.14 ALA 6 -0.67 THR 24

LYS 53 0.13 SER 7 -0.56 THR 24

LYS 53 0.15 VAL 8 -0.48 THR 24

LYS 53 0.18 ARG 9 -0.40 THR 24

LYS 53 0.17 GLY 10 -0.30 THR 24

GLU 198 0.13 GLU 11 -0.36 THR 24

LYS 53 0.12 TRP 12 -0.34 THR 24

LYS 53 0.13 PRO 13 -0.23 THR 24

ALA 237 0.13 TRP 14 -0.18 THR 24

LEU 137 0.14 GLN 15 -0.28 THR 24

LEU 137 0.19 VAL 16 -0.22 THR 24

LEU 137 0.25 THR 17 -0.30 THR 24

LEU 137 0.30 LEU 18 -0.15 ARG 26

ILE 54 0.37 HIS 19 -0.10 ARG 26

ILE 54 0.49 THR 20 -0.10 ALA 237

THR 24 0.36 THR 21 -0.16 PHE 73

LEU 137 0.38 SER 22 -0.11 PHE 73

GLY 48 1.10 PRO 23 -0.52 GLN 25

LYS 53 0.95 THR 24 -1.28 LYS 140

LYS 53 0.38 GLN 25 -0.52 PRO 23

LEU 137 0.30 ARG 26 -0.46 THR 24

ILE 54 0.32 HIS 27 -0.54 THR 24

LEU 137 0.40 LEU 28 -0.37 THR 24

LEU 137 0.37 CYS 29 -0.38 THR 24

LEU 137 0.28 GLY 30 -0.35 THR 24

LEU 137 0.23 GLY 31 -0.20 THR 24

LEU 137 0.18 SER 32 -0.15 THR 24

LEU 137 0.16 ILE 33 -0.12 ILE 67

ALA 237 0.22 ILE 34 -0.10 ILE 67

ALA 237 0.24 GLY 35 -0.09 ILE 67

ALA 237 0.19 ASN 36 -0.09 ILE 67

THR 24 0.25 GLN 37 -0.07 ILE 67

LEU 137 0.20 TRP 38 -0.08 ILE 67

LEU 137 0.21 ILE 39 -0.09 ILE 67

LEU 137 0.21 LEU 40 -0.10 ARG 26

PRO 23 0.26 THR 41 -0.11 THR 24

PRO 23 0.34 ALA 42 -0.15 THR 24

PRO 23 0.45 ALA 43 -0.19 LYS 53

PRO 23 0.52 HIS 44 -0.16 LYS 53

PRO 23 0.51 CYS 45 -0.15 THR 24

PRO 23 0.67 PHE 46 -0.26 LYS 53

PRO 23 0.80 TYR 47 -0.29 GLU 50

PRO 23 1.10 GLY 48 -0.52 GLU 50

PRO 23 0.92 VAL 49 -0.35 GLY 48

PRO 23 0.81 GLU 50 -0.52 GLY 48

THR 24 0.82 SER 51 -0.83 LYS 53

THR 24 0.66 PRO 52 -0.73 LYS 53

THR 24 0.95 LYS 53 -0.83 SER 51

THR 24 0.64 ILE 54 -0.16 ALA 237

ILE 54 0.47 LEU 55 -0.12 ALA 237

LYS 53 0.46 ARG 56 -0.14 THR 21

LYS 53 0.30 VAL 57 -0.08 ARG 26

LYS 53 0.31 TYR 58 -0.17 ILE 67

LYS 53 0.24 SER 59 -0.21 ILE 67

LYS 53 0.23 GLY 60 -0.24 ILE 67

LYS 53 0.25 ILE 61 -0.34 THR 24

LYS 53 0.21 LEU 62 -0.50 THR 24

LYS 53 0.23 ASN 63 -0.64 THR 24

LYS 53 0.26 GLN 64 -0.68 THR 24

LYS 53 0.28 SER 65 -0.67 THR 24

LYS 53 0.32 GLU 66 -0.49 ASP 70

LYS 53 0.39 ILE 67 -0.41 GLU 69

LYS 53 0.48 LYS 68 -0.94 GLU 69

LYS 53 0.80 GLU 69 -0.94 LYS 68

LYS 53 0.85 ASP 70 -0.75 LYS 68

LYS 53 0.45 THR 71 -0.36 LYS 68

LYS 53 0.44 SER 72 -0.26 PRO 23

LYS 53 0.43 PHE 73 -0.20 PRO 23

LYS 53 0.37 PHE 74 -0.10 THR 21

THR 24 0.50 GLY 75 -0.12 ALA 237

THR 24 0.49 VAL 76 -0.17 ALA 237

THR 24 0.58 GLN 77 -0.25 ALA 237

THR 24 0.49 GLU 78 -0.37 LYS 53

PRO 23 0.41 ILE 79 -0.40 LYS 53

PRO 23 0.39 ILE 80 -0.33 LYS 53

PRO 23 0.43 ILE 81 -0.31 LYS 53

PRO 23 0.38 HIS 82 -0.25 LYS 53

PRO 23 0.39 ASP 83 -0.29 LYS 53

PRO 23 0.38 GLN 84 -0.23 LYS 53

PRO 23 0.46 TYR 85 -0.20 GLY 164

PRO 23 0.52 LYS 86 -0.24 GLY 164

PRO 23 0.49 MET 87 -0.14 LYS 53

PRO 23 0.42 ALA 88 -0.22 THR 24

PRO 23 0.39 GLU 89 -0.24 THR 24

PRO 23 0.39 SER 90 -0.31 GLY 164

PRO 23 0.35 GLY 91 -0.22 GLY 164

PRO 23 0.35 TYR 92 -0.18 GLY 164

PRO 23 0.37 ASP 93 -0.16 LYS 53

PRO 23 0.32 ILE 94 -0.17 LYS 53

PRO 23 0.35 ALA 95 -0.21 LYS 53

PRO 23 0.28 LEU 96 -0.19 LYS 53

PRO 23 0.27 LEU 97 -0.14 LYS 53

THR 24 0.33 LYS 98 -0.14 THR 235

THR 24 0.37 LEU 99 -0.10 VAL 238

THR 24 0.51 GLU 100 -0.14 VAL 238

THR 24 0.42 THR 101 -0.11 VAL 238

THR 24 0.28 THR 102 -0.10 ILE 67

LYS 53 0.19 VAL 103 -0.14 ILE 67

LYS 53 0.18 ASN 104 -0.18 LYS 68

ALA 237 0.18 TYR 105 -0.19 LYS 68

LYS 53 0.16 THR 106 -0.22 LYS 68

GLU 198 0.17 ASP 107 -0.22 ASP 70

LYS 53 0.17 SER 108 -0.25 ASP 70

LYS 53 0.17 GLN 109 -0.19 ILE 67

ALA 237 0.17 ARG 110 -0.15 ILE 67

ALA 237 0.21 PRO 111 -0.13 ILE 67

ALA 237 0.21 ILE 112 -0.14 THR 24

ALA 237 0.24 SER 113 -0.11 THR 24

ALA 237 0.25 LEU 114 -0.10 THR 24

ALA 237 0.24 PRO 115 -0.14 ASN 197

ALA 237 0.26 SER 116 -0.14 ASN 197

ALA 237 0.24 LYS 117 -0.19 GLY 164

ALA 237 0.25 GLY 118 -0.32 ARG 120

ASN 121 0.31 ASP 119 -0.20 ASN 197

ALA 237 0.18 ARG 120 -0.32 GLY 118

ASP 119 0.31 ASN 121 -0.32 THR 168

ALA 237 0.18 VAL 122 -0.22 THR 168

ALA 237 0.17 ILE 123 -0.26 THR 24

ALA 237 0.16 TYR 124 -0.29 THR 24

ALA 237 0.15 THR 125 -0.33 THR 24

ALA 237 0.15 ASP 126 -0.35 THR 24

ALA 237 0.15 CYS 127 -0.37 THR 24

ARG 177 0.14 TRP 128 -0.43 THR 24

ARG 177 0.15 VAL 129 -0.47 THR 24

ILE 54 0.15 THR 130 -0.52 THR 24

ILE 54 0.18 GLY 131 -0.60 THR 24

ILE 54 0.19 TRP 132 -0.78 THR 24

LEU 137 0.24 GLY 133 -0.81 THR 24

LYS 136 0.27 TYR 134 -0.94 THR 24

TYR 134 0.24 ARG 135 -0.86 THR 24

TYR 134 0.27 LYS 136 -0.80 THR 24

LYS 185 0.63 LEU 137 -0.69 THR 24

SER 22 0.30 ARG 138 -0.93 THR 24

ILE 54 0.24 ASP 139 -1.09 THR 24

ILE 54 0.24 LYS 140 -1.28 THR 24

ILE 54 0.22 ILE 141 -1.12 THR 24

ILE 54 0.18 GLN 142 -1.05 THR 24

LYS 53 0.18 ASN 143 -0.97 THR 24

LYS 53 0.17 THR 144 -0.79 THR 24

LYS 53 0.16 LEU 145 -0.66 THR 24

ILE 54 0.15 GLN 146 -0.68 THR 24

ILE 54 0.14 LYS 147 -0.57 THR 24

ARG 177 0.16 ALA 148 -0.55 THR 24

ARG 177 0.15 LYS 149 -0.48 THR 24

ARG 177 0.18 ILE 150 -0.45 THR 24

ALA 237 0.15 PRO 151 -0.39 THR 24

ALA 237 0.15 LEU 152 -0.35 THR 24

PRO 23 0.17 VAL 153 -0.33 THR 24

PRO 23 0.19 THR 154 -0.28 ASN 121

PRO 23 0.22 ASN 155 -0.32 ASN 121

PRO 23 0.22 GLU 156 -0.30 ASN 121

PRO 23 0.21 GLU 157 -0.29 THR 24

PRO 23 0.24 CYS 158 -0.31 THR 24

PRO 23 0.27 GLN 159 -0.26 THR 24

PRO 23 0.24 LYS 160 -0.29 THR 24

PRO 23 0.25 ARG 161 -0.34 THR 24

PRO 23 0.28 TYR 162 -0.32 THR 24

PRO 23 0.29 ARG 163 -0.26 THR 24

PRO 23 0.34 GLY 164 -0.63 HIS 165

PRO 23 0.36 HIS 165 -0.63 GLY 164

PRO 23 0.35 LYS 166 -0.48 GLY 164

PRO 23 0.29 ILE 167 -0.32 GLY 164

PRO 23 0.28 THR 168 -0.32 ASN 121

PRO 23 0.23 HIS 169 -0.30 ASN 121

PRO 23 0.25 LYS 170 -0.23 GLY 164

PRO 23 0.25 MET 171 -0.23 THR 24

PRO 23 0.21 ILE 172 -0.28 THR 24

PRO 23 0.21 CYS 173 -0.34 THR 24

PRO 23 0.17 ALA 174 -0.39 THR 24

PRO 23 0.17 GLY 175 -0.44 THR 24

ARG 177 0.36 TYR 176 -0.44 THR 24

TYR 176 0.36 ARG 177 -0.38 THR 24

PRO 23 0.19 GLU 178 -0.43 THR 24

PRO 23 0.19 GLY 179 -0.48 THR 24

VAL 2 0.21 GLY 180 -0.54 THR 24

ARG 177 0.18 LYS 181 -0.56 THR 24

ARG 215 0.19 ASP 182 -0.56 THR 24

ARG 215 0.21 ALA 183 -0.59 THR 24

LEU 137 0.26 CYS 184 -0.68 THR 24

LEU 137 0.63 LYS 185 -0.72 THR 24

LEU 137 0.41 GLY 186 -0.69 THR 24

LEU 137 0.26 ASP 187 -0.59 THR 24

LEU 137 0.32 SER 188 -0.44 THR 24

LEU 137 0.28 GLY 189 -0.29 THR 24

LEU 137 0.21 GLY 190 -0.36 THR 24

ARG 215 0.15 PRO 191 -0.33 THR 24

ALA 237 0.14 LEU 192 -0.35 THR 24

ALA 237 0.16 SER 193 -0.32 THR 24

ALA 237 0.17 CYS 194 -0.30 THR 24

ALA 237 0.16 LYS 195 -0.28 THR 24

ALA 237 0.17 HIS 196 -0.24 THR 24

ALA 237 0.13 ASN 197 -0.20 ASP 119

ASP 107 0.17 GLU 198 -0.20 HIS 196

ALA 237 0.18 VAL 199 -0.20 THR 24

ALA 237 0.18 TRP 200 -0.23 THR 24

ALA 237 0.20 HIS 201 -0.20 THR 24

ALA 237 0.19 LEU 202 -0.21 THR 24

ALA 237 0.19 VAL 203 -0.24 THR 24

PRO 23 0.16 GLY 204 -0.27 THR 24

PRO 23 0.21 ILE 205 -0.27 THR 24

PRO 23 0.22 THR 206 -0.38 THR 24

PRO 23 0.31 SER 207 -0.34 THR 24

PRO 23 0.33 TRP 208 -0.40 THR 24

PRO 23 0.32 GLY 209 -0.44 THR 24

PRO 23 0.32 GLU 210 -0.46 THR 24

PRO 23 0.32 GLY 211 -0.55 THR 24

PRO 23 0.25 CYS 212 -0.60 THR 24

ARG 215 0.28 ALA 213 -0.56 THR 24

ARG 215 0.45 GLN 214 -0.51 THR 24

GLN 214 0.45 ARG 215 -0.41 THR 24

PRO 23 0.23 GLU 216 -0.40 THR 24

PRO 23 0.24 ARG 217 -0.43 THR 24

PRO 23 0.22 PRO 218 -0.42 THR 24

PRO 23 0.23 GLY 219 -0.44 THR 24

PRO 23 0.26 VAL 220 -0.36 THR 24

PRO 23 0.24 TYR 221 -0.31 THR 24

PRO 23 0.25 THR 222 -0.22 THR 24

PRO 23 0.20 ASN 223 -0.21 THR 24

ALA 237 0.20 VAL 224 -0.15 THR 24

ALA 237 0.21 VAL 225 -0.14 GLY 164

PRO 23 0.20 GLU 226 -0.18 GLY 164

PRO 23 0.22 TYR 227 -0.16 LYS 53

ALA 237 0.28 VAL 228 -0.14 LYS 53

ALA 237 0.28 ASP 229 -0.17 LYS 53

ALA 237 0.24 TRP 230 -0.21 LYS 53

ALA 237 0.30 ILE 231 -0.18 LYS 53

ALA 237 0.48 LEU 232 -0.17 LYS 53

ALA 237 0.44 GLU 233 -0.21 LYS 53

PRO 23 0.22 LYS 234 -0.25 LYS 53

ALA 237 0.42 THR 235 -0.20 LYS 53

ALA 237 0.57 GLN 236 -0.22 LYS 53

GLN 236 0.57 ALA 237 -0.35 LYS 53

THR 24 0.32 VAL 238 -0.22 LYS 53

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa WT ***

CA distance fluctuations for 2602060425492843205

--- normal mode 30 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *