Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *

CA distance fluctuations for 2602060506152857763

--- normal mode 26 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
PRO 23 0.66 ILE 1 -0.72 THR 24

PRO 23 0.68 VAL 2 -0.76 THR 24

ARG 138 0.69 GLY 3 -0.68 THR 24

ARG 138 0.64 GLY 4 -0.60 THR 24

ARG 138 0.70 THR 5 -0.53 THR 24

ARG 138 0.63 ALA 6 -0.48 THR 24

ARG 138 0.49 SER 7 -0.40 THR 24

ARG 138 0.44 VAL 8 -0.32 GLU 198

ARG 138 0.35 ARG 9 -0.30 GLU 198

ARG 138 0.27 GLY 10 -0.34 GLU 198

ARG 138 0.29 GLU 11 -0.34 GLU 198

ARG 138 0.22 TRP 12 -0.25 THR 24

ARG 138 0.16 PRO 13 -0.23 GLU 198

PRO 23 0.13 TRP 14 -0.25 ASP 70

PRO 23 0.22 GLN 15 -0.24 ARG 177

LYS 140 0.17 VAL 16 -0.31 LEU 137

PRO 23 0.20 THR 17 -0.42 LEU 137

LYS 140 0.30 LEU 18 -0.52 LEU 137

LYS 140 0.26 HIS 19 -0.59 LEU 137

LYS 140 0.32 THR 20 -0.64 LEU 137

THR 24 0.45 THR 21 -0.66 LEU 137

THR 24 0.50 SER 22 -0.67 LEU 137

LYS 140 1.16 PRO 23 -0.70 GLU 69

LYS 53 0.71 THR 24 -1.09 LEU 137

GLU 50 0.36 GLN 25 -0.59 LEU 137

GLU 69 0.35 ARG 26 -0.69 LEU 137

PRO 23 0.37 HIS 27 -0.63 LEU 137

LYS 140 0.52 LEU 28 -0.76 LEU 137

PRO 23 0.53 CYS 29 -0.65 LEU 137

PRO 23 0.42 GLY 30 -0.47 LEU 137

PRO 23 0.30 GLY 31 -0.38 LEU 137

PRO 23 0.22 SER 32 -0.29 LEU 137

LYS 140 0.17 ILE 33 -0.31 ASP 70

LYS 140 0.18 ILE 34 -0.30 ASP 70

LYS 140 0.16 GLY 35 -0.35 ASP 70

THR 24 0.18 ASN 36 -0.42 ASP 70

THR 24 0.25 GLN 37 -0.48 ASP 70

LYS 140 0.22 TRP 38 -0.39 ASP 70

LYS 140 0.24 ILE 39 -0.36 ASP 70

LYS 140 0.28 LEU 40 -0.34 LEU 137

PRO 23 0.37 THR 41 -0.41 LEU 137

PRO 23 0.52 ALA 42 -0.48 LEU 137

PRO 23 0.51 ALA 43 -0.49 LEU 137

PRO 23 0.71 HIS 44 -0.61 LEU 137

PRO 23 0.63 CYS 45 -0.67 LEU 137

LYS 140 0.51 PHE 46 -0.60 LEU 137

PRO 23 0.67 TYR 47 -0.64 LEU 137

PRO 23 0.55 GLY 48 -0.57 LEU 137

LYS 140 0.63 VAL 49 -0.43 LEU 137

THR 24 0.64 GLU 50 -0.52 ASP 83

THR 24 0.58 SER 51 -0.43 LEU 137

THR 24 0.53 PRO 52 -0.46 GLU 69

THR 24 0.71 LYS 53 -0.66 GLU 69

THR 24 0.69 ILE 54 -0.55 LEU 137

THR 24 0.40 LEU 55 -0.54 LEU 137

THR 24 0.27 ARG 56 -0.49 LEU 137

LYS 140 0.18 VAL 57 -0.43 LEU 137

TYR 105 0.14 TYR 58 -0.36 LEU 137

ILE 67 0.14 SER 59 -0.29 ASP 70

SER 108 0.24 GLY 60 -0.22 GLU 198

SER 108 0.18 ILE 61 -0.23 ARG 177

ARG 138 0.30 LEU 62 -0.32 THR 24

GLU 69 0.35 ASN 63 -0.42 THR 24

GLU 69 0.41 GLN 64 -0.48 THR 24

GLU 69 0.61 SER 65 -0.45 THR 24

GLU 69 0.40 GLU 66 -0.26 THR 24

ASP 70 0.33 ILE 67 -0.30 LEU 137

ASP 70 0.78 LYS 68 -0.47 PRO 23

SER 65 0.61 GLU 69 -0.71 GLY 75

LYS 68 0.78 ASP 70 -0.74 THR 101

LYS 68 0.32 THR 71 -0.46 PRO 23

THR 24 0.26 SER 72 -0.73 ASP 70

THR 24 0.26 PHE 73 -0.65 ASP 70

THR 24 0.34 PHE 74 -0.66 ASP 70

THR 24 0.50 GLY 75 -0.73 ASP 70

THR 24 0.43 VAL 76 -0.55 ASP 70

THR 24 0.51 GLN 77 -0.56 ASP 70

THR 24 0.42 GLU 78 -0.47 GLU 50

LYS 140 0.35 ILE 79 -0.51 GLU 50

LYS 140 0.34 ILE 80 -0.49 GLU 50

LYS 140 0.38 ILE 81 -0.50 GLU 50

LYS 140 0.35 HIS 82 -0.41 GLU 50

LYS 140 0.33 ASP 83 -0.52 GLU 50

PRO 23 0.39 GLN 84 -0.44 GLU 50

PRO 23 0.49 TYR 85 -0.43 GLU 50

PRO 23 0.58 LYS 86 -0.43 GLU 50

PRO 23 0.74 MET 87 -0.47 LEU 137

PRO 23 0.75 ALA 88 -0.49 LEU 137

PRO 23 0.75 GLU 89 -0.43 LEU 137

PRO 23 0.65 SER 90 -0.37 LEU 137

PRO 23 0.58 GLY 91 -0.35 LEU 137

PRO 23 0.49 TYR 92 -0.35 LEU 137

PRO 23 0.56 ASP 93 -0.42 LEU 137

PRO 23 0.43 ILE 94 -0.37 LEU 137

LYS 140 0.36 ALA 95 -0.40 LEU 137

LYS 140 0.32 LEU 96 -0.35 LEU 137

LYS 140 0.29 LEU 97 -0.39 ASP 70

THR 24 0.31 LYS 98 -0.46 ASP 70

THR 24 0.34 LEU 99 -0.57 ASP 70

THR 24 0.45 GLU 100 -0.71 ASP 70

THR 24 0.38 THR 101 -0.74 ASP 70

THR 24 0.29 THR 102 -0.60 ASP 70

THR 24 0.20 VAL 103 -0.51 ASP 70

THR 24 0.19 ASN 104 -0.42 ASP 70

ILE 67 0.19 TYR 105 -0.29 ASP 70

ILE 67 0.22 THR 106 -0.32 GLU 198

LYS 68 0.20 ASP 107 -0.42 GLU 198

GLY 60 0.24 SER 108 -0.33 GLU 198

ILE 67 0.12 GLN 109 -0.28 ASP 70

ILE 67 0.09 ARG 110 -0.29 ASP 70

TRP 14 0.13 PRO 111 -0.28 ASP 70

PRO 23 0.16 ILE 112 -0.23 ASP 70

PRO 23 0.17 SER 113 -0.23 ASP 70

PRO 23 0.22 LEU 114 -0.23 ASP 70

PRO 23 0.26 PRO 115 -0.21 ASP 70

ASN 197 0.27 SER 116 -0.21 ASP 70

ASN 197 0.26 LYS 117 -0.19 ASP 70

ASN 197 0.27 GLY 118 -0.20 SER 116

ASN 197 0.35 ASP 119 -0.19 ASP 70

PRO 23 0.32 ARG 120 -0.18 ASP 70

PRO 23 0.33 ASN 121 -0.18 THR 24

PRO 23 0.32 VAL 122 -0.21 THR 24

PRO 23 0.36 ILE 123 -0.25 THR 24

PRO 23 0.35 TYR 124 -0.28 THR 24

PRO 23 0.38 THR 125 -0.31 THR 24

PRO 23 0.36 ASP 126 -0.32 THR 24

PRO 23 0.41 CYS 127 -0.35 THR 24

PRO 23 0.43 TRP 128 -0.40 THR 24

PRO 23 0.50 VAL 129 -0.45 THR 24

PRO 23 0.46 THR 130 -0.47 THR 24

PRO 23 0.51 GLY 131 -0.53 THR 24

PRO 23 0.56 TRP 132 -0.66 THR 24

PRO 23 0.73 GLY 133 -0.84 THR 24

PRO 23 0.87 TYR 134 -0.95 THR 24

ARG 138 0.76 ARG 135 -0.88 THR 24

PRO 23 0.79 LYS 136 -0.96 THR 24

PRO 23 0.62 LEU 137 -1.09 THR 24

LYS 136 0.77 ARG 138 -1.03 THR 24

PRO 23 1.06 ASP 139 -1.06 THR 24

PRO 23 1.16 LYS 140 -0.94 THR 24

PRO 23 0.75 ILE 141 -1.00 THR 24

PRO 23 0.61 GLN 142 -0.79 THR 24

GLU 69 0.45 ASN 143 -0.63 THR 24

ARG 138 0.49 THR 144 -0.52 THR 24

ARG 138 0.39 LEU 145 -0.50 THR 24

ARG 138 0.50 GLN 146 -0.55 THR 24

PRO 23 0.45 LYS 147 -0.50 THR 24

PRO 23 0.50 ALA 148 -0.51 THR 24

PRO 23 0.45 LYS 149 -0.46 THR 24

PRO 23 0.50 ILE 150 -0.47 THR 24

PRO 23 0.47 PRO 151 -0.43 THR 24

PRO 23 0.48 LEU 152 -0.39 THR 24

PRO 23 0.49 VAL 153 -0.41 THR 24

PRO 23 0.47 THR 154 -0.36 THR 24

PRO 23 0.49 ASN 155 -0.35 THR 24

PRO 23 0.50 GLU 156 -0.35 THR 24

PRO 23 0.52 GLU 157 -0.41 THR 24

PRO 23 0.57 CYS 158 -0.43 THR 24

PRO 23 0.57 GLN 159 -0.40 THR 24

PRO 23 0.60 LYS 160 -0.41 THR 24

PRO 23 0.66 ARG 161 -0.47 THR 24

PRO 23 0.71 TYR 162 -0.43 THR 24

PRO 23 0.69 ARG 163 -0.39 THR 24

PRO 23 0.73 GLY 164 -0.44 ARG 138

PRO 23 0.66 HIS 165 -0.40 ARG 138

PRO 23 0.58 LYS 166 -0.33 ARG 138

PRO 23 0.57 ILE 167 -0.33 THR 24

PRO 23 0.50 THR 168 -0.26 THR 24

PRO 23 0.45 HIS 169 -0.22 THR 24

PRO 23 0.45 LYS 170 -0.25 LEU 137

PRO 23 0.52 MET 171 -0.28 THR 24

PRO 23 0.51 ILE 172 -0.32 THR 24

PRO 23 0.56 CYS 173 -0.41 THR 24

PRO 23 0.55 ALA 174 -0.46 THR 24

PRO 23 0.57 GLY 175 -0.53 THR 24

PRO 23 0.54 TYR 176 -0.89 ARG 177

PRO 23 0.53 ARG 177 -0.89 TYR 176

PRO 23 0.53 GLU 178 -0.65 THR 24

PRO 23 0.60 GLY 179 -0.66 THR 24

PRO 23 0.59 GLY 180 -0.71 THR 24

PRO 23 0.60 LYS 181 -0.64 THR 24

PRO 23 0.66 ASP 182 -0.64 THR 24

PRO 23 0.70 ALA 183 -0.65 THR 24

PRO 23 0.85 CYS 184 -0.78 THR 24

PRO 23 0.98 LYS 185 -0.99 LEU 137

PRO 23 0.81 GLY 186 -0.77 THR 24

PRO 23 0.68 ASP 187 -0.60 THR 24

PRO 23 0.70 SER 188 -0.60 LEU 137

PRO 23 0.52 GLY 189 -0.48 LEU 137

PRO 23 0.46 GLY 190 -0.35 LEU 137

PRO 23 0.41 PRO 191 -0.31 THR 24

PRO 23 0.45 LEU 192 -0.34 THR 24

PRO 23 0.35 SER 193 -0.28 THR 24

PRO 23 0.34 CYS 194 -0.27 THR 24

PRO 23 0.28 LYS 195 -0.24 THR 24

PRO 23 0.26 HIS 196 -0.25 ASP 107

ASP 119 0.35 ASN 197 -0.36 ASP 107

HIS 196 0.26 GLU 198 -0.42 ASP 107

PRO 23 0.19 VAL 199 -0.29 ASN 197

PRO 23 0.23 TRP 200 -0.22 ASP 107

PRO 23 0.26 HIS 201 -0.20 ASP 70

PRO 23 0.31 LEU 202 -0.20 ASP 70

PRO 23 0.37 VAL 203 -0.22 THR 24

PRO 23 0.45 GLY 204 -0.26 THR 24

PRO 23 0.49 ILE 205 -0.32 LEU 137

PRO 23 0.61 THR 206 -0.41 THR 24

PRO 23 0.69 SER 207 -0.47 LEU 137

PRO 23 0.81 TRP 208 -0.54 LEU 137

PRO 23 0.83 GLY 209 -0.58 THR 24

PRO 23 0.89 GLU 210 -0.62 THR 24

PRO 23 0.92 GLY 211 -0.74 THR 24

PRO 23 0.82 CYS 212 -0.77 THR 24

PRO 23 0.69 ALA 213 -0.73 THR 24

PRO 23 0.73 GLN 214 -0.69 THR 24

PRO 23 0.60 ARG 215 -0.69 THR 24

PRO 23 0.64 GLU 216 -0.58 THR 24

PRO 23 0.71 ARG 217 -0.58 THR 24

PRO 23 0.64 PRO 218 -0.55 THR 24

PRO 23 0.68 GLY 219 -0.54 THR 24

PRO 23 0.65 VAL 220 -0.45 THR 24

PRO 23 0.58 TYR 221 -0.36 THR 24

PRO 23 0.51 THR 222 -0.31 LEU 137

PRO 23 0.45 ASN 223 -0.23 ASN 155

PRO 23 0.37 VAL 224 -0.22 LEU 137

PRO 23 0.33 VAL 225 -0.19 ASP 70

PRO 23 0.35 GLU 226 -0.22 LEU 137

PRO 23 0.31 TYR 227 -0.24 LEU 137

PRO 23 0.25 VAL 228 -0.22 ASP 70

PRO 23 0.21 ASP 229 -0.23 GLU 50

LYS 140 0.25 TRP 230 -0.27 GLU 50

LYS 140 0.24 ILE 231 -0.26 ASP 70

LYS 140 0.22 LEU 232 -0.26 ASP 70

LYS 140 0.23 GLU 233 -0.27 ASP 70

LYS 140 0.26 LYS 234 -0.30 ASP 70

LYS 140 0.23 THR 235 -0.32 ASP 70

THR 24 0.24 GLN 236 -0.36 ALA 237

THR 24 0.30 ALA 237 -0.36 GLN 236

THR 24 0.34 VAL 238 -0.34 ASP 70

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa WT ***

CA distance fluctuations for 2602060506152857763

--- normal mode 26 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *