Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *

CA distance fluctuations for 2602060506152857763

--- normal mode 29 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
PRO 23 0.27 ILE 1 -0.80 THR 24

ARG 215 0.32 VAL 2 -0.87 THR 24

GLU 198 0.32 GLY 3 -0.82 THR 24

GLU 198 0.39 GLY 4 -0.76 THR 24

GLU 198 0.47 THR 5 -0.73 THR 24

GLU 198 0.49 ALA 6 -0.70 THR 24

GLU 198 0.51 SER 7 -0.52 THR 24

GLU 198 0.58 VAL 8 -0.43 THR 24

GLU 198 0.48 ARG 9 -0.42 GLU 69

GLU 198 0.54 GLY 10 -0.39 GLU 69

GLU 198 0.61 GLU 11 -0.30 GLU 69

GLU 198 0.44 TRP 12 -0.26 GLU 69

GLU 198 0.40 PRO 13 -0.33 ASP 70

LEU 137 0.25 TRP 14 -0.26 ASP 70

LEU 137 0.27 GLN 15 -0.24 ASP 70

LEU 137 0.28 VAL 16 -0.22 ASP 70

LEU 137 0.31 THR 17 -0.24 LYS 140

LEU 137 0.35 LEU 18 -0.41 LYS 140

LEU 137 0.32 HIS 19 -0.48 LYS 140

GLU 69 0.33 THR 20 -0.58 LYS 140

GLU 69 0.53 THR 21 -0.58 LYS 140

GLU 69 0.50 SER 22 -0.60 LYS 140

GLY 48 1.05 PRO 23 -0.36 LYS 68

LYS 53 0.73 THR 24 -1.50 ASP 139

GLU 69 0.50 GLN 25 -0.50 THR 21

GLU 69 0.25 ARG 26 -0.60 LYS 140

LEU 137 0.34 HIS 27 -0.54 LYS 140

PRO 23 0.52 LEU 28 -0.68 LYS 140

LEU 137 0.52 CYS 29 -0.53 LYS 140

LEU 137 0.44 GLY 30 -0.32 LYS 140

LEU 137 0.38 GLY 31 -0.27 LYS 140

LEU 137 0.33 SER 32 -0.20 ASP 70

LEU 137 0.28 ILE 33 -0.24 ASP 70

LEU 137 0.28 ILE 34 -0.22 ALA 237

LEU 137 0.25 GLY 35 -0.32 ALA 237

LEU 137 0.21 ASN 36 -0.31 ALA 237

THR 24 0.26 GLN 37 -0.23 ALA 237

LEU 137 0.27 TRP 38 -0.23 LYS 140

LEU 137 0.32 ILE 39 -0.26 LYS 140

LEU 137 0.35 LEU 40 -0.28 LYS 140

LEU 137 0.42 THR 41 -0.37 LYS 140

PRO 23 0.48 ALA 42 -0.47 LYS 140

PRO 23 0.52 ALA 43 -0.54 LYS 140

PRO 23 0.64 HIS 44 -0.66 LYS 140

PRO 23 0.67 CYS 45 -0.67 LYS 140

PRO 23 0.71 PHE 46 -0.63 LYS 140

PRO 23 0.86 TYR 47 -0.68 LYS 140

PRO 23 1.05 GLY 48 -0.62 LYS 140

PRO 23 0.90 VAL 49 -0.46 LYS 140

PRO 23 0.89 GLU 50 -0.54 SER 51

THR 24 0.60 SER 51 -0.54 GLU 50

THR 24 0.57 PRO 52 -0.43 LYS 140

THR 24 0.73 LYS 53 -0.43 LYS 140

THR 24 0.59 ILE 54 -0.52 LYS 140

THR 24 0.37 LEU 55 -0.48 LYS 140

THR 24 0.29 ARG 56 -0.38 LYS 140

LEU 137 0.26 VAL 57 -0.30 LYS 140

GLU 198 0.22 TYR 58 -0.25 ASP 70

GLU 198 0.26 SER 59 -0.37 ASP 70

GLU 198 0.33 GLY 60 -0.45 ASP 70

GLU 198 0.30 ILE 61 -0.46 GLU 69

GLU 198 0.37 LEU 62 -0.45 GLU 69

GLU 198 0.32 ASN 63 -0.53 THR 24

GLU 198 0.25 GLN 64 -0.54 THR 24

GLU 198 0.24 SER 65 -0.51 THR 24

GLU 198 0.23 GLU 66 -0.70 GLU 69

GLU 198 0.18 ILE 67 -0.61 GLU 69

GLN 25 0.18 LYS 68 -0.89 GLU 69

THR 24 0.68 GLU 69 -0.89 LYS 68

THR 24 0.60 ASP 70 -0.68 THR 106

THR 24 0.21 THR 71 -0.81 GLU 69

THR 24 0.28 SER 72 -0.56 ASP 70

THR 24 0.28 PHE 73 -0.26 ASP 70

THR 24 0.35 PHE 74 -0.25 LYS 140

THR 24 0.54 GLY 75 -0.30 LYS 140

THR 24 0.49 VAL 76 -0.34 LYS 140

THR 24 0.59 GLN 77 -0.43 GLU 50

THR 24 0.48 GLU 78 -0.46 GLU 50

THR 24 0.33 ILE 79 -0.40 LYS 140

ALA 237 0.45 ILE 80 -0.38 LYS 140

ALA 237 0.43 ILE 81 -0.45 LYS 140

ALA 237 0.44 HIS 82 -0.47 GLY 164

ALA 237 0.60 ASP 83 -0.56 GLY 164

ALA 237 0.46 GLN 84 -0.69 GLY 164

ALA 237 0.44 TYR 85 -0.65 GLY 164

ALA 237 0.40 LYS 86 -0.65 LYS 140

PRO 23 0.46 MET 87 -0.69 LYS 140

PRO 23 0.50 ALA 88 -0.60 LYS 140

PRO 23 0.44 GLU 89 -0.53 LYS 140

PRO 23 0.40 SER 90 -0.75 GLY 164

PRO 23 0.40 GLY 91 -0.61 GLY 164

PRO 23 0.38 TYR 92 -0.53 GLY 164

PRO 23 0.46 ASP 93 -0.47 LYS 140

PRO 23 0.40 ILE 94 -0.41 LYS 140

PRO 23 0.38 ALA 95 -0.41 LYS 140

LEU 137 0.33 LEU 96 -0.34 LYS 140

LEU 137 0.31 LEU 97 -0.35 LYS 140

THR 24 0.35 LYS 98 -0.29 LYS 140

THR 24 0.38 LEU 99 -0.28 GLU 50

THR 24 0.53 GLU 100 -0.33 GLU 50

THR 24 0.42 THR 101 -0.28 GLU 50

THR 24 0.30 THR 102 -0.30 ASP 70

ASN 197 0.25 VAL 103 -0.41 ASP 70

ASN 197 0.36 ASN 104 -0.60 ASP 70

ASN 197 0.43 TYR 105 -0.59 ASP 70

GLU 198 0.56 THR 106 -0.68 ASP 70

GLU 198 0.70 ASP 107 -0.60 ASP 70

GLU 198 0.52 SER 108 -0.58 ASP 70

GLU 198 0.36 GLN 109 -0.44 ASP 70

ASN 197 0.32 ARG 110 -0.35 ASP 70

ASN 197 0.23 PRO 111 -0.29 ASP 70

LEU 137 0.26 ILE 112 -0.24 ASP 70

LEU 137 0.24 SER 113 -0.21 ALA 237

LEU 137 0.26 LEU 114 -0.20 ALA 237

LEU 137 0.25 PRO 115 -0.33 GLU 198

LEU 137 0.22 SER 116 -0.37 GLU 198

LEU 137 0.23 LYS 117 -0.34 ASN 197

LEU 137 0.20 GLY 118 -0.43 ASN 197

LEU 137 0.20 ASP 119 -0.52 ASN 197

LEU 152 0.22 ARG 120 -0.39 ASN 197

ILE 123 0.38 ASN 121 -0.35 ASN 197

THR 125 0.33 VAL 122 -0.39 ASN 197

ASN 121 0.38 ILE 123 -0.33 ASN 197

THR 125 0.26 TYR 124 -0.29 HIS 196

VAL 122 0.33 THR 125 -0.33 THR 24

VAL 122 0.25 ASP 126 -0.33 THR 24

PRO 23 0.23 CYS 127 -0.36 THR 24

PRO 23 0.23 TRP 128 -0.42 THR 24

LEU 137 0.28 VAL 129 -0.48 THR 24

LEU 137 0.29 THR 130 -0.50 THR 24

LEU 137 0.31 GLY 131 -0.57 THR 24

LEU 137 0.25 TRP 132 -0.74 THR 24

LEU 137 0.40 GLY 133 -0.86 THR 24

ARG 135 0.26 TYR 134 -1.11 THR 24

ARG 215 0.39 ARG 135 -1.09 THR 24

ARG 215 0.50 LYS 136 -1.15 THR 24

LYS 185 0.97 LEU 137 -0.96 THR 24

PRO 23 0.64 ARG 138 -1.15 THR 24

ARG 215 0.33 ASP 139 -1.50 THR 24

GLN 142 0.41 LYS 140 -1.23 THR 24

GLU 198 0.21 ILE 141 -1.11 THR 24

LYS 140 0.41 GLN 142 -1.07 THR 24

LYS 140 0.35 ASN 143 -0.90 THR 24

GLU 198 0.39 THR 144 -0.75 THR 24

GLU 198 0.37 LEU 145 -0.62 THR 24

GLU 198 0.39 GLN 146 -0.69 THR 24

GLU 198 0.39 LYS 147 -0.58 THR 24

GLU 198 0.33 ALA 148 -0.59 THR 24

GLU 198 0.28 LYS 149 -0.50 THR 24

PRO 23 0.25 ILE 150 -0.50 THR 24

PRO 23 0.24 PRO 151 -0.45 THR 24

PRO 23 0.27 LEU 152 -0.40 THR 24

PRO 23 0.28 VAL 153 -0.40 THR 24

PRO 23 0.28 THR 154 -0.35 THR 24

PRO 23 0.30 ASN 155 -0.34 THR 24

PRO 23 0.29 GLU 156 -0.34 THR 24

PRO 23 0.29 GLU 157 -0.40 THR 24

PRO 23 0.32 CYS 158 -0.43 THR 24

PRO 23 0.32 GLN 159 -0.39 THR 24

ARG 163 0.37 LYS 160 -0.42 THR 24

ARG 163 0.40 ARG 161 -0.48 THR 24

PRO 23 0.35 TYR 162 -0.48 THR 24

ARG 161 0.40 ARG 163 -0.76 HIS 165

ARG 138 0.54 GLY 164 -0.78 LYS 166

ARG 138 0.41 HIS 165 -0.76 ARG 163

PRO 23 0.37 LYS 166 -0.78 GLY 164

PRO 23 0.36 ILE 167 -0.41 GLY 164

PRO 23 0.34 THR 168 -0.48 GLY 164

PRO 23 0.31 HIS 169 -0.40 GLY 164

PRO 23 0.32 LYS 170 -0.44 GLY 164

PRO 23 0.34 MET 171 -0.33 GLY 164

PRO 23 0.33 ILE 172 -0.33 THR 24

PRO 23 0.33 CYS 173 -0.42 THR 24

PRO 23 0.31 ALA 174 -0.47 THR 24

PRO 23 0.29 GLY 175 -0.54 THR 24

PRO 23 0.26 TYR 176 -0.56 THR 24

GLY 179 0.29 ARG 177 -0.54 THR 24

GLY 180 0.40 GLU 178 -0.75 ARG 215

GLU 178 0.38 GLY 179 -0.67 THR 24

GLU 178 0.40 GLY 180 -0.74 THR 24

GLU 178 0.26 LYS 181 -0.70 THR 24

PRO 23 0.31 ASP 182 -0.69 THR 24

LEU 137 0.44 ALA 183 -0.69 THR 24

LEU 137 0.76 CYS 184 -0.81 THR 24

LEU 137 0.97 LYS 185 -0.83 THR 24

LEU 137 0.61 GLY 186 -0.73 THR 24

LEU 137 0.56 ASP 187 -0.61 THR 24

LEU 137 0.63 SER 188 -0.48 LYS 140

LEU 137 0.51 GLY 189 -0.40 LYS 140

LEU 137 0.45 GLY 190 -0.34 THR 24

LEU 137 0.37 PRO 191 -0.30 THR 24

LEU 137 0.33 LEU 192 -0.34 THR 24

LEU 137 0.27 SER 193 -0.28 THR 24

LEU 137 0.22 CYS 194 -0.27 THR 24

ASP 107 0.32 LYS 195 -0.22 THR 24

ASP 107 0.38 HIS 196 -0.32 GLU 198

ASP 107 0.62 ASN 197 -0.52 ASP 119

ASP 107 0.70 GLU 198 -0.44 ASP 119

ASN 197 0.43 VAL 199 -0.22 GLU 198

ASP 107 0.30 TRP 200 -0.19 ASP 70

LEU 137 0.24 HIS 201 -0.18 GLU 198

LEU 137 0.29 LEU 202 -0.18 THR 24

LEU 137 0.28 VAL 203 -0.23 THR 24

LEU 137 0.34 GLY 204 -0.27 THR 24

LEU 137 0.41 ILE 205 -0.28 THR 24

LEU 137 0.51 THR 206 -0.41 THR 24

LEU 137 0.50 SER 207 -0.46 LYS 140

LEU 137 0.54 TRP 208 -0.53 THR 24

PRO 23 0.46 GLY 209 -0.61 THR 24

ARG 138 0.45 GLU 210 -0.66 THR 24

PRO 23 0.46 GLY 211 -0.78 THR 24

PRO 23 0.41 CYS 212 -0.81 THR 24

ARG 215 0.48 ALA 213 -0.75 THR 24

ARG 215 1.08 GLN 214 -0.72 THR 24

GLN 214 1.08 ARG 215 -0.75 GLU 178

PRO 23 0.31 GLU 216 -0.55 THR 24

PRO 23 0.35 ARG 217 -0.59 THR 24

PRO 23 0.34 PRO 218 -0.55 THR 24

PRO 23 0.38 GLY 219 -0.55 THR 24

PRO 23 0.40 VAL 220 -0.45 THR 24

LEU 137 0.39 TYR 221 -0.37 THR 24

PRO 23 0.37 THR 222 -0.32 LYS 140

PRO 23 0.31 ASN 223 -0.28 GLY 164

LEU 137 0.30 VAL 224 -0.26 GLY 164

LEU 137 0.26 VAL 225 -0.27 ASN 197

PRO 23 0.26 GLU 226 -0.35 GLY 164

LEU 137 0.27 TYR 227 -0.36 GLY 164

LEU 137 0.26 VAL 228 -0.30 GLY 164

LEU 137 0.24 ASP 229 -0.34 GLY 164

LEU 137 0.26 TRP 230 -0.38 GLY 164

LEU 137 0.27 ILE 231 -0.31 GLY 164

GLU 233 0.33 LEU 232 -0.36 ALA 237

LEU 232 0.33 GLU 233 -0.34 GLY 164

THR 235 0.26 LYS 234 -0.33 GLY 164

LYS 234 0.26 THR 235 -0.34 ALA 237

THR 24 0.24 GLN 236 -1.03 ALA 237

ASP 83 0.60 ALA 237 -1.03 GLN 236

THR 24 0.33 VAL 238 -0.26 THR 101

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa WT ***

CA distance fluctuations for 2602060506152857763

--- normal mode 29 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *