Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *

CA distance fluctuations for 2602061617263047109

--- normal mode 25 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
PRO 23 0.49 ILE 1 -0.58 THR 24

PRO 23 0.51 VAL 2 -0.60 THR 24

PRO 23 0.44 GLY 3 -0.59 THR 24

PRO 23 0.36 GLY 4 -0.58 THR 24

GLU 69 0.26 THR 5 -0.62 THR 24

GLU 69 0.33 ALA 6 -0.67 THR 24

GLU 69 0.35 SER 7 -0.58 THR 24

GLU 69 0.40 VAL 8 -0.55 THR 24

GLU 69 0.44 ARG 9 -0.54 THR 24

GLU 69 0.38 GLY 10 -0.42 THR 24

GLU 69 0.35 GLU 11 -0.40 THR 24

GLU 69 0.32 TRP 12 -0.34 THR 24

GLU 69 0.35 PRO 13 -0.27 THR 24

GLU 69 0.27 TRP 14 -0.17 THR 24

GLU 69 0.26 GLN 15 -0.25 THR 24

GLU 69 0.25 VAL 16 -0.21 THR 24

GLU 69 0.19 THR 17 -0.28 THR 24

PRO 23 0.16 LEU 18 -0.25 VAL 49

ALA 237 0.20 HIS 19 -0.36 VAL 49

ALA 237 0.24 THR 20 -0.52 VAL 49

THR 24 0.39 THR 21 -0.71 GLU 69

THR 24 0.68 SER 22 -0.73 GLU 69

MET 87 1.15 PRO 23 -1.15 ASP 70

LYS 53 0.83 THR 24 -1.06 SER 65

ALA 237 0.25 GLN 25 -0.52 SER 22

LYS 68 0.19 ARG 26 -0.45 THR 24

PRO 23 0.21 HIS 27 -0.43 THR 24

PRO 23 0.43 LEU 28 -0.41 VAL 49

PRO 23 0.48 CYS 29 -0.25 VAL 49

PRO 23 0.38 GLY 30 -0.20 THR 24

PRO 23 0.33 GLY 31 -0.11 LEU 137

PRO 23 0.25 SER 32 -0.13 ASN 197

GLU 198 0.27 ILE 33 -0.19 ASN 197

GLU 198 0.37 ILE 34 -0.24 ASN 197

GLN 236 0.42 GLY 35 -0.28 ASN 197

GLN 236 0.41 ASN 36 -0.25 ASN 197

GLN 236 0.29 GLN 37 -0.22 ASN 197

GLU 198 0.28 TRP 38 -0.21 ASN 197

GLU 198 0.24 ILE 39 -0.16 ASN 197

PRO 23 0.36 LEU 40 -0.14 ASN 197

PRO 23 0.48 THR 41 -0.12 LEU 137

PRO 23 0.67 ALA 42 -0.13 LEU 137

PRO 23 0.75 ALA 43 -0.19 ILE 80

PRO 23 0.94 HIS 44 -0.16 LEU 137

PRO 23 0.75 CYS 45 -0.23 LEU 137

PRO 23 0.69 PHE 46 -0.23 TYR 47

PRO 23 0.96 TYR 47 -0.29 GLU 69

PRO 23 0.78 GLY 48 -0.46 GLU 69

ASP 83 0.54 VAL 49 -0.55 GLU 69

ASP 83 0.75 GLU 50 -0.71 GLU 69

THR 24 0.82 SER 51 -0.54 GLU 69

THR 24 0.70 PRO 52 -0.39 GLU 69

THR 24 0.83 LYS 53 -0.62 GLU 69

THR 24 0.78 ILE 54 -0.67 GLU 69

THR 24 0.45 LEU 55 -0.35 VAL 49

ALA 237 0.26 ARG 56 -0.26 VAL 49

ALA 237 0.23 VAL 57 -0.19 VAL 49

GLU 69 0.31 TYR 58 -0.19 VAL 49

GLU 69 0.36 SER 59 -0.23 THR 24

GLU 69 0.45 GLY 60 -0.36 THR 24

GLU 69 0.50 ILE 61 -0.51 THR 24

GLU 69 0.48 LEU 62 -0.64 THR 24

GLU 69 0.50 GLN 63 -0.80 THR 24

GLU 69 0.42 GLN 64 -0.86 THR 24

GLU 69 0.51 SER 65 -1.06 THR 24

GLU 69 0.75 GLU 66 -0.78 THR 24

GLU 69 0.55 ILE 67 -0.51 THR 24

GLU 69 0.56 LYS 68 -0.63 PRO 23

THR 71 0.82 GLU 69 -1.09 PRO 23

THR 71 0.48 ASP 70 -1.15 PRO 23

GLU 69 0.82 THR 71 -0.71 PRO 23

GLU 69 0.40 SER 72 -0.63 PRO 23

ALA 237 0.25 PHE 73 -0.41 PRO 23

ALA 237 0.31 PHE 74 -0.29 PRO 23

THR 24 0.41 GLY 75 -0.27 PRO 23

THR 24 0.48 VAL 76 -0.17 LEU 137

THR 24 0.58 GLN 77 -0.16 LEU 137

THR 24 0.56 GLU 78 -0.26 ILE 79

THR 24 0.50 ILE 79 -0.26 GLU 78

GLU 50 0.56 ILE 80 -0.19 ILE 81

GLU 50 0.60 ILE 81 -0.23 GLN 236

PRO 23 0.63 HIS 82 -0.29 GLN 236

GLU 50 0.75 ASP 83 -0.37 GLN 236

PRO 23 0.81 GLN 84 -0.28 GLN 236

PRO 23 0.88 TYR 85 -0.29 GLN 236

PRO 23 1.07 LYS 86 -0.25 GLN 236

PRO 23 1.15 MET 87 -0.19 GLN 236

PRO 23 1.03 ALA 88 -0.15 GLN 236

PRO 23 1.05 GLU 89 -0.16 LYS 166

PRO 23 0.99 SER 90 -0.14 GLN 236

PRO 23 0.87 GLY 91 -0.15 GLN 236

PRO 23 0.79 TYR 92 -0.19 GLN 236

PRO 23 0.81 ASP 93 -0.17 GLN 236

PRO 23 0.65 ILE 94 -0.18 GLN 236

PRO 23 0.53 ALA 95 -0.14 GLN 236

GLU 50 0.36 LEU 96 -0.14 VAL 238

THR 24 0.33 LEU 97 -0.15 LEU 137

THR 24 0.39 LYS 98 -0.16 ASN 197

ALA 237 0.38 LEU 99 -0.17 ASN 197

ALA 237 0.44 GLU 100 -0.23 PRO 23

ALA 237 0.37 THR 101 -0.28 PRO 23

ALA 237 0.32 THR 102 -0.22 PRO 23

GLN 236 0.38 VAL 103 -0.22 PRO 23

GLN 236 0.45 GLN 104 -0.31 PRO 23

GLU 198 0.43 TYR 105 -0.21 ILE 67

GLU 198 0.41 THR 106 -0.26 ILE 67

GLU 198 0.43 ASP 107 -0.31 THR 24

GLU 69 0.33 SER 108 -0.37 THR 24

GLU 69 0.34 GLN 109 -0.21 THR 24

GLU 198 0.38 ARG 110 -0.21 ASN 197

GLU 198 0.42 PRO 111 -0.26 ASN 197

GLU 198 0.41 ILE 112 -0.28 ASN 197

GLU 198 0.61 SER 113 -0.36 ASN 197

GLU 198 0.46 LEU 114 -0.29 ASN 197

GLU 198 0.43 PRO 115 -0.24 ALA 237

GLU 198 0.51 SER 116 -0.28 ALA 237

SER 116 0.47 LYS 117 -0.22 ALA 237

GLU 198 0.42 GLY 118 -0.23 ALA 237

PRO 23 0.38 ASP 119 -0.23 ALA 237

PRO 23 0.46 ARG 120 -0.21 ILE 123

PRO 23 0.45 ASN 121 -0.27 ILE 123

PRO 23 0.41 VAL 122 -0.20 ALA 237

PRO 23 0.43 ILE 123 -0.27 ASN 121

PRO 23 0.41 TYR 124 -0.28 THR 125

ASN 197 0.47 THR 125 -0.42 GLU 198

ASN 197 0.40 ASP 126 -0.53 GLU 198

PRO 23 0.39 CYS 127 -0.32 GLU 198

PRO 23 0.38 TRP 128 -0.33 THR 24

PRO 23 0.44 VAL 129 -0.35 THR 24

PRO 23 0.36 THR 130 -0.41 THR 24

PRO 23 0.36 GLY 131 -0.48 THR 24

PRO 23 0.31 TRP 132 -0.65 THR 24

PRO 23 0.49 GLY 133 -0.62 THR 24

PRO 23 0.55 TYR 134 -0.71 THR 24

PRO 23 0.49 ARG 135 -0.73 THR 24

PRO 23 0.59 LYS 136 -0.69 THR 24

PRO 23 0.66 LEU 137 -0.66 THR 24

PRO 23 0.69 ARG 138 -0.75 THR 24

PRO 23 0.58 ASP 139 -0.84 THR 24

PRO 23 0.50 LYS 140 -1.01 THR 24

PRO 23 0.36 ILE 141 -0.90 THR 24

PRO 23 0.25 GLN 142 -0.93 THR 24

GLU 69 0.32 ASN 143 -1.04 THR 24

GLU 69 0.37 THR 144 -0.83 THR 24

GLU 69 0.33 LEU 145 -0.65 THR 24

PRO 23 0.26 GLN 146 -0.62 THR 24

PRO 23 0.30 LYS 147 -0.51 THR 24

PRO 23 0.38 ALA 148 -0.46 THR 24

PRO 23 0.39 LYS 149 -0.44 GLU 198

PRO 23 0.47 ILE 150 -0.35 THR 24

PRO 23 0.49 PRO 151 -0.34 GLU 198

PRO 23 0.54 LEU 152 -0.22 THR 24

PRO 23 0.59 VAL 153 -0.20 THR 24

PRO 23 0.60 THR 154 -0.16 ALA 237

PRO 23 0.66 ASN 155 -0.18 HIS 169

PRO 23 0.66 GLU 156 -0.15 HIS 169

PRO 23 0.66 GLU 157 -0.18 THR 24

PRO 23 0.72 CYS 158 -0.17 THR 24

PRO 23 0.75 GLN 159 -0.23 ARG 163

PRO 23 0.76 LYS 160 -0.17 THR 24

PRO 23 0.79 ARG 161 -0.29 GLY 164

PRO 23 0.89 TYR 162 -0.29 ARG 163

PRO 23 0.90 ARG 163 -0.29 TYR 162

PRO 23 0.88 GLY 164 -0.53 GLN 214

PRO 23 0.90 HIS 165 -0.23 LEU 137

GLY 164 0.87 LYS 166 -0.17 LEU 137

PRO 23 0.79 ILE 167 -0.11 ALA 237

PRO 23 0.74 THR 168 -0.12 SER 90

PRO 23 0.66 HIS 169 -0.18 ASN 155

PRO 23 0.68 LYS 170 -0.16 ALA 237

PRO 23 0.72 MET 171 -0.15 ALA 237

PRO 23 0.66 ILE 172 -0.16 ALA 237

PRO 23 0.67 CYS 173 -0.17 THR 24

PRO 23 0.61 ALA 174 -0.25 THR 24

PRO 23 0.60 GLY 175 -0.33 THR 24

PRO 23 0.56 TYR 176 -0.42 ARG 177

PRO 23 0.60 ARG 177 -0.42 TYR 176

PRO 23 0.57 GLU 178 -0.43 THR 24

PRO 23 0.60 GLY 179 -0.44 THR 24

PRO 23 0.54 GLY 180 -0.52 THR 24

PRO 23 0.52 LYS 181 -0.48 THR 24

PRO 23 0.60 ASP 182 -0.44 THR 24

PRO 23 0.62 ALA 183 -0.42 THR 24

PRO 23 0.71 CYS 184 -0.47 THR 24

PRO 23 0.77 LYS 185 -0.45 THR 24

PRO 23 0.61 GLY 186 -0.44 THR 24

PRO 23 0.57 ASP 187 -0.38 THR 24

PRO 23 0.69 SER 188 -0.19 THR 24

PRO 23 0.58 GLY 189 -0.12 LEU 137

PRO 23 0.46 GLY 190 -0.20 THR 24

PRO 23 0.43 PRO 191 -0.19 THR 24

PRO 23 0.47 LEU 192 -0.21 THR 24

PRO 23 0.36 SER 193 -0.21 THR 24

PRO 23 0.35 CYS 194 -0.20 THR 24

PRO 23 0.28 LYS 195 -0.26 GLU 198

PRO 23 0.28 HIS 196 -0.17 ALA 237

THR 125 0.47 ASN 197 -0.52 VAL 199

VAL 199 0.67 GLU 198 -0.53 ASP 126

GLU 198 0.67 VAL 199 -0.52 ASN 197

GLU 198 0.27 TRP 200 -0.23 ASN 197

GLU 198 0.33 HIS 201 -0.20 ASN 197

PRO 23 0.37 LEU 202 -0.16 ALA 237

PRO 23 0.46 VAL 203 -0.18 ALA 237

PRO 23 0.55 GLY 204 -0.15 ALA 237

PRO 23 0.58 ILE 205 -0.12 ALA 237

PRO 23 0.67 THR 206 -0.17 THR 24

PRO 23 0.82 SER 207 -0.12 ALA 42

PRO 23 0.93 TRP 208 -0.17 THR 24

PRO 23 0.92 GLY 209 -0.25 THR 24

PRO 23 0.97 GLU 210 -0.49 GLY 164

PRO 23 0.90 GLY 211 -0.50 GLY 164

PRO 23 0.76 CYS 212 -0.47 THR 24

PRO 23 0.66 ALA 213 -0.48 THR 24

PRO 23 0.72 GLN 214 -0.53 GLY 164

PRO 23 0.65 ARG 215 -0.51 GLY 164

PRO 23 0.71 GLU 216 -0.41 GLY 164

PRO 23 0.79 ARG 217 -0.41 GLY 164

PRO 23 0.72 PRO 218 -0.30 THR 24

PRO 23 0.74 GLY 219 -0.27 THR 24

PRO 23 0.78 VAL 220 -0.16 THR 24

PRO 23 0.71 TYR 221 -0.13 ALA 237

PRO 23 0.69 THR 222 -0.16 ALA 237

PRO 23 0.61 ASN 223 -0.18 ALA 237

PRO 23 0.52 VAL 224 -0.20 ALA 237

PRO 23 0.48 VAL 225 -0.22 ALA 237

PRO 23 0.55 GLU 226 -0.21 ALA 237

PRO 23 0.51 TYR 227 -0.24 ALA 237

PRO 23 0.41 VAL 228 -0.29 ALA 237

PRO 23 0.40 ASP 229 -0.31 ALA 237

PRO 23 0.44 TRP 230 -0.29 ALA 237

GLU 50 0.37 ILE 231 -0.29 ALA 237

GLU 198 0.37 LEU 232 -0.47 ALA 237

GLU 50 0.41 GLU 233 -0.53 GLN 236

GLU 50 0.46 LYS 234 -0.55 GLN 236

GLU 50 0.35 THR 235 -0.24 ALA 237

GLU 198 0.48 GLN 236 -0.78 ALA 237

THR 24 0.50 ALA 237 -0.78 GLN 236

GLU 198 0.33 VAL 238 -0.25 GLN 236

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa WT ***

CA distance fluctuations for 2602061617263047109

--- normal mode 25 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *