Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *

CA distance fluctuations for 2602061617263047109

--- normal mode 27 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
GLU 198 0.20 ILE 1 -0.29 THR 24

GLU 198 0.30 VAL 2 -0.31 THR 24

GLU 198 0.41 GLY 3 -0.31 ASN 197

GLU 198 0.37 GLY 4 -0.34 ASN 197

GLU 198 0.33 THR 5 -0.37 ASN 197

ASP 70 0.38 ALA 6 -0.31 ASN 197

ASP 70 0.37 SER 7 -0.28 ASN 197

ASP 70 0.43 VAL 8 -0.26 ASN 197

ASP 70 0.42 ARG 9 -0.19 THR 144

ASP 70 0.32 GLY 10 -0.19 GLY 118

ASP 70 0.29 GLU 11 -0.19 GLN 236

ASP 70 0.22 TRP 12 -0.20 GLN 236

ILE 67 0.17 PRO 13 -0.32 GLU 198

ASN 197 0.22 TRP 14 -0.38 GLU 198

ILE 67 0.18 GLN 15 -0.23 GLU 198

ILE 67 0.20 VAL 16 -0.31 LEU 137

ILE 67 0.15 THR 17 -0.38 ARG 138

PRO 23 0.12 LEU 18 -0.49 ARG 138

ASN 197 0.08 HIS 19 -0.57 ARG 138

THR 24 0.21 THR 20 -0.67 ARG 138

THR 24 0.54 THR 21 -0.64 ARG 138

THR 24 0.87 SER 22 -0.77 ARG 138

GLY 48 0.79 PRO 23 -0.72 LYS 68

SER 22 0.87 THR 24 -0.90 ARG 138

ALA 237 0.07 GLN 25 -0.62 ARG 138

GLN 64 0.12 ARG 26 -0.69 ARG 138

PRO 23 0.17 HIS 27 -0.60 ARG 138

PRO 23 0.36 LEU 28 -0.70 ARG 138

PRO 23 0.30 CYS 29 -0.57 LEU 137

PRO 23 0.20 GLY 30 -0.42 LEU 137

PRO 23 0.16 GLY 31 -0.36 LEU 137

ASN 197 0.21 SER 32 -0.33 GLU 198

ASN 197 0.33 ILE 33 -0.47 GLU 198

ASN 197 0.46 ILE 34 -0.58 GLU 198

ASN 197 0.51 GLY 35 -0.66 GLU 198

GLN 104 0.47 ASN 36 -0.61 GLU 198

ASN 197 0.37 GLN 37 -0.53 GLU 198

ASN 197 0.37 TRP 38 -0.50 GLU 198

ASN 197 0.30 ILE 39 -0.40 GLU 198

ASN 197 0.28 LEU 40 -0.33 GLU 198

PRO 23 0.23 THR 41 -0.40 LEU 137

PRO 23 0.32 ALA 42 -0.45 LEU 137

PRO 23 0.36 ALA 43 -0.47 LEU 137

PRO 23 0.45 HIS 44 -0.57 LEU 137

PRO 23 0.45 CYS 45 -0.64 LEU 137

PRO 23 0.47 PHE 46 -0.62 ARG 138

PRO 23 0.58 TYR 47 -0.58 ARG 138

PRO 23 0.79 GLY 48 -0.74 VAL 49

PRO 23 0.43 VAL 49 -0.74 GLY 48

LYS 86 0.30 GLU 50 -0.58 GLY 48

THR 24 0.41 SER 51 -0.53 ARG 138

THR 24 0.38 PRO 52 -0.51 ARG 138

THR 24 0.47 LYS 53 -0.54 ASP 70

THR 24 0.56 ILE 54 -0.57 ARG 138

THR 24 0.32 LEU 55 -0.55 ARG 138

ASN 197 0.15 ARG 56 -0.47 ARG 138

ASN 197 0.17 VAL 57 -0.42 ARG 138

ILE 67 0.28 TYR 58 -0.35 ARG 138

ILE 67 0.21 SER 59 -0.31 GLN 104

ILE 67 0.21 GLY 60 -0.34 GLN 104

ASP 70 0.34 ILE 61 -0.33 GLN 104

ASP 70 0.43 LEU 62 -0.32 GLN 63

ASP 70 0.46 GLN 63 -0.34 GLN 104

ASP 70 0.36 GLN 64 -0.35 THR 24

ASP 70 0.49 SER 65 -0.48 ILE 67

ASP 70 0.64 GLU 66 -0.44 GLN 104

ASP 70 0.51 ILE 67 -0.48 SER 65

ASP 70 0.97 LYS 68 -0.72 PRO 23

GLU 66 0.27 GLU 69 -0.69 PRO 23

LYS 68 0.97 ASP 70 -0.62 PRO 23

ILE 67 0.29 THR 71 -0.41 PRO 23

ILE 67 0.21 SER 72 -0.44 GLN 104

ILE 67 0.25 PHE 73 -0.39 GLN 104

ASN 197 0.23 PHE 74 -0.38 ASP 70

THR 24 0.23 GLY 75 -0.48 ASP 70

THR 24 0.25 VAL 76 -0.43 ARG 138

THR 24 0.27 GLN 77 -0.41 VAL 238

ASN 197 0.25 GLU 78 -0.43 ARG 138

ASN 197 0.24 ILE 79 -0.46 ARG 138

GLN 236 0.31 ILE 80 -0.41 ARG 138

PRO 23 0.27 ILE 81 -0.42 ARG 138

GLN 236 0.28 HIS 82 -0.36 ARG 138

GLN 236 0.41 ASP 83 -0.38 ARG 138

GLN 236 0.32 GLN 84 -0.35 ARG 138

PRO 23 0.35 TYR 85 -0.39 LEU 137

PRO 23 0.39 LYS 86 -0.45 LEU 137

PRO 23 0.41 MET 87 -0.48 LEU 137

PRO 23 0.40 ALA 88 -0.43 LEU 137

PRO 23 0.37 GLU 89 -0.32 LEU 137

PRO 23 0.36 SER 90 -0.29 LEU 137

PRO 23 0.32 GLY 91 -0.28 LEU 137

PRO 23 0.30 TYR 92 -0.31 LEU 137

PRO 23 0.33 ASP 93 -0.38 LEU 137

PRO 23 0.27 ILE 94 -0.36 LEU 137

ASN 197 0.25 ALA 95 -0.40 ARG 138

ASN 197 0.30 LEU 96 -0.38 ARG 138

ASN 197 0.27 LEU 97 -0.40 ARG 138

ASN 197 0.30 LYS 98 -0.42 GLU 198

ASN 197 0.28 LEU 99 -0.41 GLU 198

ASN 197 0.27 GLU 100 -0.39 ASP 70

ASN 197 0.31 THR 101 -0.42 GLU 198

ASN 197 0.37 THR 102 -0.49 GLU 198

ASN 197 0.41 VAL 103 -0.44 GLU 198

ASN 197 0.54 GLN 104 -0.44 GLU 66

ASN 197 0.49 TYR 105 -0.49 GLU 198

ASN 197 0.40 THR 106 -0.38 GLU 198

ASN 197 0.24 ASP 107 -0.37 GLU 198

ASP 70 0.22 SER 108 -0.30 GLU 198

ASN 197 0.27 GLN 109 -0.39 GLU 198

ASN 197 0.41 ARG 110 -0.56 GLU 198

ASN 197 0.49 PRO 111 -0.65 GLU 198

ASN 197 0.47 ILE 112 -0.61 GLU 198

ASN 197 0.70 SER 113 -0.75 GLU 198

ASN 197 0.62 LEU 114 -0.57 GLU 198

ASN 197 0.55 PRO 115 -0.44 GLU 198

ASN 197 0.61 SER 116 -0.57 GLU 198

THR 168 0.43 LYS 117 -0.53 GLN 236

ARG 120 0.79 GLY 118 -0.68 GLU 198

ASN 197 0.32 ASP 119 -0.37 ASN 121

GLY 118 0.79 ARG 120 -0.56 ASN 121

GLY 118 0.50 ASN 121 -0.56 ARG 120

GLY 118 0.31 VAL 122 -0.28 GLN 236

GLU 198 0.52 ILE 123 -0.24 GLN 236

GLU 198 0.51 TYR 124 -0.35 ASN 197

GLU 198 0.77 THR 125 -0.73 ASN 197

GLU 198 0.77 ASP 126 -0.74 ASN 197

GLU 198 0.45 CYS 127 -0.43 ASN 197

GLU 198 0.33 TRP 128 -0.36 ASN 197

GLU 198 0.20 VAL 129 -0.22 ASN 197

ASP 70 0.19 THR 130 -0.17 ASN 197

ASP 70 0.16 GLY 131 -0.23 THR 24

ASP 70 0.19 TRP 132 -0.32 THR 24

LYS 185 0.18 GLY 133 -0.37 LEU 137

LYS 140 0.28 TYR 134 -0.44 THR 24

ARG 138 0.25 ARG 135 -0.43 THR 24

ARG 138 0.43 LYS 136 -0.53 THR 24

ARG 215 0.59 LEU 137 -0.83 LYS 185

GLU 178 0.47 ARG 138 -0.90 THR 24

ARG 215 0.25 ASP 139 -0.70 THR 24

LYS 185 0.31 LYS 140 -0.75 THR 24

LYS 185 0.19 ILE 141 -0.54 THR 24

ASP 70 0.23 GLN 142 -0.43 THR 24

ASP 70 0.35 ASN 143 -0.39 THR 24

ASP 70 0.41 THR 144 -0.29 THR 24

ASP 70 0.33 LEU 145 -0.25 THR 24

ASP 70 0.28 GLN 146 -0.25 THR 24

GLU 198 0.26 LYS 147 -0.31 ASN 197

GLU 198 0.40 ALA 148 -0.39 ASN 197

GLU 198 0.54 LYS 149 -0.52 ASN 197

GLU 198 0.49 ILE 150 -0.45 ASN 197

GLU 198 0.55 PRO 151 -0.47 ASN 197

GLU 198 0.41 LEU 152 -0.32 ASN 197

GLY 118 0.41 VAL 153 -0.26 ASN 197

GLY 118 0.55 THR 154 -0.21 HIS 169

GLY 118 0.59 ASN 155 -0.17 HIS 169

GLY 118 0.62 GLU 156 -0.24 THR 168

GLY 118 0.52 GLU 157 -0.16 ASN 197

GLY 118 0.48 CYS 158 -0.13 ASN 197

GLY 118 0.54 GLN 159 -0.12 LYS 86

GLY 118 0.47 LYS 160 -0.13 ASN 197

GLY 118 0.39 ARG 161 -0.17 ASN 197

GLY 118 0.40 TYR 162 -0.18 GLY 164

GLY 118 0.48 ARG 163 -0.19 GLU 178

HIS 165 0.46 GLY 164 -0.27 ARG 215

GLY 164 0.46 HIS 165 -0.13 GLU 178

GLY 118 0.51 LYS 166 -0.16 GLU 156

GLY 118 0.51 ILE 167 -0.20 GLU 156

GLY 118 0.57 THR 168 -0.24 GLU 156

GLY 118 0.57 HIS 169 -0.21 ILE 123

GLY 118 0.43 LYS 170 -0.17 ALA 237

GLY 118 0.41 MET 171 -0.15 ALA 237

GLY 118 0.40 ILE 172 -0.16 ALA 237

GLY 118 0.37 CYS 173 -0.14 ALA 237

GLU 198 0.32 ALA 174 -0.25 ASN 197

GLU 198 0.39 GLY 175 -0.32 ASN 197

GLU 198 0.46 TYR 176 -0.40 ASN 197

LEU 137 0.43 ARG 177 -0.39 ASN 197

LEU 137 0.55 GLU 178 -0.36 ASN 197

LEU 137 0.49 GLY 179 -0.31 ASN 197

LEU 137 0.49 GLY 180 -0.31 ASN 197

GLU 198 0.41 LYS 181 -0.34 ASN 197

GLU 198 0.31 ASP 182 -0.25 ASN 197

PRO 23 0.22 ALA 183 -0.20 THR 24

LYS 140 0.27 CYS 184 -0.32 LEU 137

LYS 140 0.31 LYS 185 -0.83 LEU 137

PRO 23 0.28 GLY 186 -0.63 LEU 137

PRO 23 0.25 ASP 187 -0.41 LEU 137

PRO 23 0.33 SER 188 -0.49 LEU 137

PRO 23 0.28 GLY 189 -0.42 LEU 137

PRO 23 0.21 GLY 190 -0.31 LEU 137

PRO 23 0.18 PRO 191 -0.19 LEU 137

PRO 23 0.18 LEU 192 -0.18 GLN 236

PRO 23 0.13 SER 193 -0.23 GLN 236

GLU 198 0.20 CYS 194 -0.24 GLN 236

GLU 198 0.28 LYS 195 -0.29 ASN 197

GLU 198 0.21 HIS 196 -0.24 GLN 236

SER 113 0.70 ASN 197 -0.74 ASP 126

ASP 126 0.77 GLU 198 -0.78 GLN 236

ASN 197 0.38 VAL 199 -0.55 GLU 198

ASN 197 0.22 TRP 200 -0.32 GLU 198

ASN 197 0.34 HIS 201 -0.35 GLU 198

ASN 197 0.26 LEU 202 -0.27 GLN 236

PRO 23 0.17 VAL 203 -0.23 GLN 236

PRO 23 0.21 GLY 204 -0.17 ALA 237

PRO 23 0.24 ILE 205 -0.24 LEU 137

PRO 23 0.28 THR 206 -0.28 LEU 137

PRO 23 0.35 SER 207 -0.35 LEU 137

PRO 23 0.37 TRP 208 -0.32 LEU 137

PRO 23 0.33 GLY 209 -0.19 GLY 179

PRO 23 0.32 GLU 210 -0.25 GLN 214

LYS 140 0.28 GLY 211 -0.22 THR 24

LYS 140 0.24 CYS 212 -0.26 THR 24

LEU 137 0.48 ALA 213 -0.25 THR 24

LEU 137 0.55 GLN 214 -0.25 GLU 210

LEU 137 0.59 ARG 215 -0.28 ASN 197

LEU 137 0.42 GLU 216 -0.28 ASN 197

LEU 137 0.32 ARG 217 -0.23 GLY 179

GLY 118 0.30 PRO 218 -0.22 ASN 197

PRO 23 0.27 GLY 219 -0.17 GLY 175

PRO 23 0.30 VAL 220 -0.14 GLY 91

PRO 23 0.28 TYR 221 -0.15 LEU 137

PRO 23 0.28 THR 222 -0.19 LEU 137

GLY 118 0.28 ASN 223 -0.19 ALA 237

ASN 197 0.29 VAL 224 -0.22 ALA 237

ASN 197 0.38 VAL 225 -0.29 ALA 237

LYS 117 0.34 GLU 226 -0.26 ALA 237

ASN 197 0.40 TYR 227 -0.26 ALA 237

ASN 197 0.54 VAL 228 -0.36 GLU 198

ASN 197 0.56 ASP 229 -0.40 ALA 237

ASN 197 0.46 TRP 230 -0.31 GLU 198

ASN 197 0.48 ILE 231 -0.40 GLU 198

ASN 197 0.57 LEU 232 -0.56 ALA 237

ASN 197 0.48 GLU 233 -0.46 ALA 237

GLN 236 0.60 LYS 234 -0.41 GLU 198

ASN 197 0.40 THR 235 -0.55 GLU 198

VAL 238 0.65 GLN 236 -0.78 GLU 198

GLN 104 0.33 ALA 237 -0.60 GLU 198

GLN 236 0.65 VAL 238 -0.42 GLU 78

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa WT ***

CA distance fluctuations for 2602061617263047109

--- normal mode 27 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa WT *