Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *

CA distance fluctuations for 2602061647033086323

--- normal mode 24 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
GLY 3 0.09 ILE 1 -0.35 ASN 197

GLY 3 0.11 VAL 2 -0.40 ASN 197

VAL 2 0.11 GLY 3 -0.51 ASN 197

ILE 1 0.09 GLY 4 -0.55 ASN 197

GLN 146 0.11 THR 5 -0.61 ASN 197

THR 24 0.11 ALA 6 -0.55 ASN 197

THR 24 0.09 SER 7 -0.55 ASN 197

THR 24 0.11 VAL 8 -0.57 ASN 197

THR 24 0.15 ARG 9 -0.56 GLU 198

THR 24 0.09 GLY 10 -0.63 GLU 198

PRO 13 0.04 GLU 11 -0.56 GLU 198

PRO 13 0.06 TRP 12 -0.47 GLU 198

ASP 107 0.08 PRO 13 -0.50 GLU 198

LEU 137 0.08 TRP 14 -0.38 GLU 198

LEU 137 0.09 GLN 15 -0.35 GLU 198

LEU 137 0.11 VAL 16 -0.31 GLU 198

LEU 137 0.12 THR 17 -0.27 GLU 198

LYS 68 0.18 LEU 18 -0.23 GLU 198

LYS 68 0.37 HIS 19 -0.22 GLU 198

LYS 68 0.48 THR 20 -0.22 THR 24

LYS 68 0.74 THR 21 -0.21 LYS 86

LYS 68 0.68 SER 22 -0.32 THR 24

LYS 68 0.93 PRO 23 -0.89 GLY 48

LYS 68 1.17 THR 24 -0.50 GLY 48

LYS 68 0.81 GLN 25 -0.20 GLU 198

LYS 68 0.56 ARG 26 -0.20 GLU 198

LYS 68 0.34 HIS 27 -0.21 GLU 198

LYS 68 0.29 LEU 28 -0.35 PRO 23

LEU 137 0.20 CYS 29 -0.30 PRO 23

LEU 137 0.18 GLY 30 -0.21 GLU 198

LEU 137 0.15 GLY 31 -0.21 GLU 198

LEU 137 0.13 SER 32 -0.25 GLU 198

ASN 197 0.20 ILE 33 -0.30 GLU 198

ASN 197 0.36 ILE 34 -0.23 GLU 198

ASN 197 0.42 GLY 35 -0.24 GLU 198

GLN 104 0.49 ASN 36 -0.29 ILE 67

THR 102 0.34 GLN 37 -0.26 GLU 198

ASN 197 0.30 TRP 38 -0.23 GLU 198

ASN 197 0.21 ILE 39 -0.22 GLU 198

ASN 197 0.23 LEU 40 -0.16 PRO 23

GLY 164 0.18 THR 41 -0.22 PRO 23

GLY 164 0.22 ALA 42 -0.32 PRO 23

GLY 164 0.25 ALA 43 -0.38 PRO 23

GLY 164 0.24 HIS 44 -0.49 PRO 23

ARG 138 0.29 CYS 45 -0.47 PRO 23

TYR 47 0.62 PHE 46 -0.48 PRO 23

PHE 46 0.62 TYR 47 -0.66 PRO 23

GLU 50 0.85 GLY 48 -0.89 PRO 23

GLY 48 0.71 VAL 49 -0.38 ASP 83

GLY 48 0.85 GLU 50 -0.53 ASP 83

GLY 48 0.83 SER 51 -0.27 VAL 238

GLY 48 0.66 PRO 52 -0.25 VAL 238

GLY 48 0.50 LYS 53 -0.25 VAL 238

LYS 68 0.48 ILE 54 -0.21 SER 22

LYS 68 0.34 LEU 55 -0.19 GLU 198

ASP 70 0.30 ARG 56 -0.23 GLU 198

ASP 70 0.17 VAL 57 -0.30 ILE 67

GLY 48 0.09 TYR 58 -0.55 ILE 67

GLY 48 0.07 SER 59 -0.55 ILE 67

THR 24 0.11 GLY 60 -0.52 ILE 67

THR 24 0.15 ILE 61 -0.45 ILE 67

THR 24 0.17 LEU 62 -0.41 GLU 198

THR 24 0.22 GLN 63 -0.37 ASP 70

ILE 67 0.38 GLN 64 -0.36 ASP 70

ILE 67 0.69 SER 65 -0.51 ASP 70

GLU 69 0.37 GLU 66 -0.55 ASP 70

THR 24 0.69 ILE 67 -0.81 THR 71

THR 24 1.17 LYS 68 -1.19 ASP 70

LYS 68 0.59 GLU 69 -0.32 GLN 104

PRO 23 0.53 ASP 70 -1.19 LYS 68

PRO 23 0.30 THR 71 -0.81 ILE 67

PRO 23 0.24 SER 72 -0.71 ILE 67

ASP 70 0.28 PHE 73 -0.58 ILE 67

ASP 70 0.32 PHE 74 -0.40 ILE 67

ASP 70 0.45 GLY 75 -0.22 ILE 67

GLY 48 0.42 VAL 76 -0.22 VAL 238

GLY 48 0.48 GLN 77 -0.31 VAL 238

GLY 48 0.56 GLU 78 -0.32 VAL 238

GLY 48 0.54 ILE 79 -0.31 GLU 50

GLY 48 0.42 ILE 80 -0.35 GLU 50

ALA 237 0.33 ILE 81 -0.42 GLU 50

TYR 85 0.48 HIS 82 -0.36 GLU 50

ALA 237 0.53 ASP 83 -0.53 GLU 50

ALA 237 0.43 GLN 84 -0.43 GLU 50

HIS 82 0.48 TYR 85 -0.45 PRO 23

ALA 237 0.39 LYS 86 -0.60 PRO 23

GLY 164 0.34 MET 87 -0.51 PRO 23

GLY 164 0.30 ALA 88 -0.42 PRO 23

GLY 164 0.35 GLU 89 -0.38 PRO 23

GLY 164 0.47 SER 90 -0.38 PRO 23

GLY 164 0.37 GLY 91 -0.35 PRO 23

ALA 237 0.31 TYR 92 -0.34 PRO 23

GLY 164 0.29 ASP 93 -0.34 PRO 23

GLY 164 0.24 ILE 94 -0.29 PRO 23

GLY 164 0.26 ALA 95 -0.26 GLU 50

GLY 48 0.27 LEU 96 -0.22 GLU 50

GLY 48 0.36 LEU 97 -0.18 GLU 198

GLY 48 0.37 LYS 98 -0.22 VAL 238

GLY 48 0.33 LEU 99 -0.23 ILE 67

ASP 70 0.38 GLU 100 -0.24 ILE 67

ASP 70 0.29 THR 101 -0.33 ILE 67

GLN 37 0.34 THR 102 -0.36 ILE 67

ASN 36 0.48 VAL 103 -0.51 ILE 67

ASN 36 0.49 GLN 104 -0.64 ILE 67

GLN 104 0.25 TYR 105 -0.46 ILE 67

PRO 111 0.16 THR 106 -0.47 ILE 67

PRO 111 0.10 ASP 107 -0.59 GLU 198

THR 24 0.07 SER 108 -0.54 GLU 198

PRO 111 0.11 GLN 109 -0.47 ILE 67

PRO 111 0.19 ARG 110 -0.44 GLU 198

GLN 104 0.29 PRO 111 -0.37 GLU 198

ASN 197 0.27 ILE 112 -0.32 GLU 198

ASN 197 0.51 SER 113 -0.19 GLU 198

ASN 197 0.57 LEU 114 -0.17 LYS 117

ASN 197 0.62 PRO 115 -0.25 LYS 117

ASN 197 0.82 SER 116 -0.32 LYS 117

ASN 197 0.67 LYS 117 -0.32 SER 116

ASN 197 0.74 GLY 118 -0.31 SER 116

ASN 197 0.64 ASP 119 -0.21 CYS 127

ASN 197 0.42 ARG 120 -0.23 CYS 127

HIS 169 0.30 ASN 121 -0.28 CYS 127

GLU 198 0.30 VAL 122 -0.32 CYS 127

GLU 198 0.45 ILE 123 -0.26 ASN 121

GLU 198 0.44 TYR 124 -0.38 CYS 127

GLU 198 0.48 THR 125 -0.62 ASN 197

GLU 198 0.35 ASP 126 -0.70 ASN 197

GLU 198 0.17 CYS 127 -0.43 ASN 197

ILE 112 0.09 TRP 128 -0.43 ASN 197

ARG 110 0.08 VAL 129 -0.32 ASN 197

LYS 147 0.09 THR 130 -0.31 ASN 197

LEU 137 0.09 GLY 131 -0.26 ASN 197

ILE 67 0.10 TRP 132 -0.26 ASN 197

LEU 137 0.14 GLY 133 -0.24 PRO 23

ILE 67 0.16 TYR 134 -0.28 ASN 197

ILE 67 0.13 ARG 135 -0.39 ARG 138

ILE 67 0.15 LYS 136 -0.46 ARG 138

LYS 185 0.32 LEU 137 -0.29 ARG 215

VAL 49 0.35 ARG 138 -0.57 ASP 139

ILE 67 0.23 ASP 139 -0.57 ARG 138

ILE 67 0.29 LYS 140 -0.25 ASN 197

ILE 67 0.30 ILE 141 -0.24 ASN 197

ILE 67 0.25 GLN 142 -0.31 ASN 197

ILE 67 0.30 ASN 143 -0.35 ASP 70

THR 24 0.17 THR 144 -0.38 ASN 197

THR 24 0.09 LEU 145 -0.36 ASN 197

THR 5 0.11 GLN 146 -0.45 ASN 197

THR 130 0.09 LYS 147 -0.50 ASN 197

TRP 14 0.06 ALA 148 -0.54 ASN 197

ILE 112 0.09 LYS 149 -0.60 ASN 197

GLU 198 0.12 ILE 150 -0.48 ASN 197

GLU 198 0.26 PRO 151 -0.42 ASN 197

GLU 198 0.28 LEU 152 -0.23 ASN 121

GLU 198 0.27 VAL 153 -0.21 PRO 23

GLU 198 0.29 THR 154 -0.20 PRO 23

GLU 198 0.25 ASN 155 -0.23 PRO 23

GLU 198 0.24 GLU 156 -0.22 PRO 23

GLU 198 0.23 GLU 157 -0.21 PRO 23

GLU 198 0.20 CYS 158 -0.23 PRO 23

ILE 167 0.21 GLN 159 -0.24 PRO 23

GLU 198 0.17 LYS 160 -0.22 PRO 23

ALA 237 0.16 ARG 161 -0.29 GLY 164

ALA 237 0.19 TYR 162 -0.29 GLY 164

HIS 165 0.54 ARG 163 -0.29 ARG 161

HIS 165 0.63 GLY 164 -0.31 ARG 215

GLY 164 0.63 HIS 165 -0.32 PRO 23

GLY 164 0.40 LYS 166 -0.31 PRO 23

GLY 164 0.23 ILE 167 -0.28 PRO 23

HIS 169 0.36 THR 168 -0.28 PRO 23

THR 168 0.36 HIS 169 -0.24 PRO 23

ASN 197 0.30 LYS 170 -0.26 PRO 23

GLY 164 0.20 MET 171 -0.26 PRO 23

GLU 198 0.20 ILE 172 -0.24 PRO 23

GLU 198 0.19 CYS 173 -0.23 PRO 23

GLU 198 0.17 ALA 174 -0.22 PRO 23

GLU 198 0.15 GLY 175 -0.31 ASN 197

ARG 215 0.18 TYR 176 -0.39 ASN 197

ARG 215 0.22 ARG 177 -0.30 ASN 197

ARG 215 0.30 GLU 178 -0.36 ASN 197

GLN 214 0.11 GLY 179 -0.36 ASN 197

ALA 213 0.14 GLY 180 -0.44 ASN 197

GLY 35 0.06 LYS 181 -0.45 ASN 197

GLY 35 0.08 ASP 182 -0.34 ASN 197

LEU 137 0.10 ALA 183 -0.26 PRO 23

LEU 137 0.23 CYS 184 -0.31 PRO 23

LEU 137 0.32 LYS 185 -0.36 PRO 23

LEU 137 0.22 GLY 186 -0.33 PRO 23

LEU 137 0.18 ASP 187 -0.27 PRO 23

LEU 137 0.21 SER 188 -0.33 PRO 23

LEU 137 0.18 GLY 189 -0.28 PRO 23

LEU 137 0.15 GLY 190 -0.21 PRO 23

LEU 137 0.10 PRO 191 -0.19 PRO 23

ILE 112 0.10 LEU 192 -0.20 PRO 23

ILE 112 0.10 SER 193 -0.20 LYS 117

LYS 195 0.16 CYS 194 -0.25 VAL 122

GLU 198 0.19 LYS 195 -0.33 ASN 197

GLU 198 0.52 HIS 196 -0.27 ARG 9

SER 116 0.82 ASN 197 -0.70 ASP 126

HIS 196 0.52 GLU 198 -0.63 GLY 10

ASN 197 0.16 VAL 199 -0.30 GLU 198

GLN 104 0.13 TRP 200 -0.25 GLU 198

ASN 197 0.26 HIS 201 -0.20 LYS 117

ASN 197 0.20 LEU 202 -0.20 LYS 117

ASN 197 0.17 VAL 203 -0.23 LYS 117

GLN 104 0.14 GLY 204 -0.21 PRO 23

GLY 35 0.13 ILE 205 -0.24 PRO 23

LEU 137 0.15 THR 206 -0.28 PRO 23

ALA 42 0.20 SER 207 -0.32 PRO 23

ARG 138 0.17 TRP 208 -0.35 PRO 23

ALA 237 0.14 ALA 209 -0.33 PRO 23

ALA 237 0.14 GLU 210 -0.33 PRO 23

ARG 138 0.12 GLY 211 -0.34 PRO 23

GLY 180 0.09 CYS 212 -0.30 PRO 23

GLY 180 0.14 ALA 213 -0.31 ASN 197

GLY 179 0.11 GLN 214 -0.51 ARG 215

GLU 178 0.30 ARG 215 -0.51 GLN 214

GLU 198 0.15 GLU 216 -0.26 GLY 179

GLU 216 0.13 ARG 217 -0.27 GLY 164

GLU 198 0.13 PRO 218 -0.25 PRO 23

ALA 237 0.11 ALA 219 -0.27 PRO 23

ALA 237 0.14 VAL 220 -0.28 PRO 23

GLY 35 0.13 TYR 221 -0.27 PRO 23

GLY 164 0.19 THR 222 -0.26 PRO 23

ASN 197 0.25 ASN 223 -0.23 PRO 23

ASN 197 0.36 VAL 224 -0.19 PRO 23

ASN 197 0.51 VAL 225 -0.18 PRO 23

ASN 197 0.46 GLU 226 -0.20 PRO 23

ASN 197 0.49 TYR 227 -0.20 PRO 23

ASN 197 0.63 VAL 228 -0.18 GLU 50

ASN 197 0.64 ASP 229 -0.21 GLU 50

ASN 197 0.52 TRP 230 -0.25 GLU 50

ASN 197 0.52 ILE 231 -0.23 GLU 50

ASN 197 0.63 LEU 232 -0.21 GLU 50

ASN 197 0.58 GLU 233 -0.27 GLU 50

ASN 197 0.47 LYS 234 -0.29 GLU 50

ASN 197 0.49 THR 235 -0.21 GLU 50

ASN 197 0.57 GLN 236 -0.79 ALA 237

ASP 83 0.53 ALA 237 -0.79 GLN 236

ASN 197 0.52 VAL 238 -0.32 GLU 78

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A-G226A ***

CA distance fluctuations for 2602061647033086323

--- normal mode 24 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *