Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *

CA distance fluctuations for 2602061647033086323

--- normal mode 25 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
THR 24 0.48 ILE 1 -0.47 PRO 23

THR 24 0.48 VAL 2 -0.51 PRO 23

THR 24 0.48 GLY 3 -0.44 PRO 23

THR 24 0.51 GLY 4 -0.35 PRO 23

THR 24 0.57 THR 5 -0.27 GLU 69

THR 24 0.65 ALA 6 -0.34 GLU 69

THR 24 0.59 SER 7 -0.37 GLU 69

THR 24 0.58 VAL 8 -0.43 GLU 69

THR 24 0.58 ARG 9 -0.51 GLU 69

THR 24 0.45 GLY 10 -0.47 GLU 69

THR 24 0.42 GLU 11 -0.40 GLU 69

THR 24 0.35 TRP 12 -0.37 GLU 69

THR 24 0.29 PRO 13 -0.43 ASP 70

THR 24 0.18 TRP 14 -0.34 ASP 70

THR 24 0.25 GLN 15 -0.31 GLU 69

THR 24 0.21 VAL 16 -0.29 GLU 69

VAL 49 0.28 THR 17 -0.20 GLU 69

VAL 49 0.34 LEU 18 -0.15 PRO 23

VAL 49 0.47 HIS 19 -0.15 ASP 83

VAL 49 0.66 THR 20 -0.22 THR 24

GLU 69 0.86 THR 21 -0.40 THR 24

GLU 69 0.98 SER 22 -0.75 THR 24

ASP 70 1.29 PRO 23 -1.20 MET 87

SER 65 1.19 THR 24 -0.80 ILE 54

SER 22 0.62 GLN 25 -0.22 ARG 56

GLU 50 0.48 ARG 26 -0.17 LYS 68

VAL 49 0.47 HIS 27 -0.22 ILE 67

VAL 49 0.55 LEU 28 -0.42 PRO 23

VAL 49 0.34 CYS 29 -0.47 PRO 23

VAL 49 0.23 GLY 30 -0.36 PRO 23

VAL 49 0.13 GLY 31 -0.31 PRO 23

THR 102 0.09 SER 32 -0.24 PRO 23

GLN 104 0.12 ILE 33 -0.29 ASP 70

GLY 35 0.21 ILE 34 -0.25 ASP 70

ILE 34 0.21 GLY 35 -0.30 ASP 70

GLN 104 0.17 ASN 36 -0.36 ASP 70

THR 102 0.11 GLN 37 -0.24 ASP 70

TYR 85 0.10 TRP 38 -0.25 GLU 50

TYR 85 0.08 ILE 39 -0.20 PRO 23

TYR 85 0.09 LEU 40 -0.35 PRO 23

ALA 237 0.07 THR 41 -0.48 PRO 23

ALA 237 0.13 ALA 42 -0.67 PRO 23

ALA 237 0.21 ALA 43 -0.76 PRO 23

ALA 237 0.19 HIS 44 -0.95 PRO 23

VAL 49 0.19 CYS 45 -0.76 PRO 23

GLU 69 0.28 PHE 46 -0.71 PRO 23

GLU 69 0.36 TYR 47 -0.96 PRO 23

GLU 69 0.57 GLY 48 -0.68 PRO 23

GLU 69 0.69 VAL 49 -0.66 ASP 83

GLU 69 0.88 GLU 50 -0.89 ASP 83

GLU 69 0.68 SER 51 -0.77 THR 24

GLU 69 0.48 PRO 52 -0.66 THR 24

GLU 69 0.74 LYS 53 -0.78 THR 24

GLU 69 0.80 ILE 54 -0.80 THR 24

GLU 69 0.38 LEU 55 -0.45 THR 24

LYS 53 0.30 ARG 56 -0.22 GLN 25

VAL 49 0.21 VAL 57 -0.13 VAL 103

VAL 49 0.22 TYR 58 -0.37 GLU 69

THR 24 0.24 SER 59 -0.47 GLU 69

THR 24 0.38 GLY 60 -0.59 GLU 69

THR 24 0.54 ILE 61 -0.58 GLU 69

THR 24 0.67 LEU 62 -0.53 GLU 69

THR 24 0.86 GLN 63 -0.52 GLU 69

THR 24 0.93 GLN 64 -0.44 ILE 67

THR 24 1.19 SER 65 -0.45 GLU 69

THR 24 0.90 GLU 66 -0.77 GLU 69

THR 24 0.58 ILE 67 -0.47 GLU 69

PRO 23 0.66 LYS 68 -0.37 GLU 69

PRO 23 1.13 GLU 69 -0.95 THR 71

PRO 23 1.29 ASP 70 -0.74 GLN 104

PRO 23 0.69 THR 71 -0.95 GLU 69

PRO 23 0.56 SER 72 -0.64 GLU 69

PRO 23 0.36 PHE 73 -0.33 GLU 69

PRO 23 0.25 PHE 74 -0.17 THR 24

PRO 23 0.24 GLY 75 -0.39 THR 24

GLU 69 0.16 VAL 76 -0.44 THR 24

GLU 69 0.20 GLN 77 -0.51 THR 24

GLU 69 0.21 GLU 78 -0.51 THR 24

GLU 69 0.19 ILE 79 -0.54 GLU 50

ALA 237 0.27 ILE 80 -0.64 GLU 50

ALA 237 0.32 ILE 81 -0.68 GLU 50

ALA 237 0.34 HIS 82 -0.65 PRO 23

ALA 237 0.48 ASP 83 -0.89 GLU 50

ALA 237 0.34 GLN 84 -0.86 PRO 23

ALA 237 0.35 TYR 85 -0.92 PRO 23

ALA 237 0.32 LYS 86 -1.12 PRO 23

ALA 237 0.24 MET 87 -1.20 PRO 23

ALA 237 0.17 ALA 88 -1.06 PRO 23

LYS 166 0.23 GLU 89 -1.06 PRO 23

THR 168 0.15 SER 90 -1.01 PRO 23

ALA 237 0.14 GLY 91 -0.89 PRO 23

ALA 237 0.18 TYR 92 -0.81 PRO 23

ALA 237 0.17 ASP 93 -0.83 PRO 23

ALA 237 0.17 ILE 94 -0.66 PRO 23

ALA 237 0.19 ALA 95 -0.53 PRO 23

ALA 237 0.13 LEU 96 -0.41 GLU 50

TYR 85 0.10 LEU 97 -0.32 THR 24

TYR 85 0.10 LYS 98 -0.35 THR 24

ASN 197 0.10 LEU 99 -0.32 THR 24

PRO 23 0.19 GLU 100 -0.40 THR 24

PRO 23 0.22 THR 101 -0.29 THR 24

ASN 197 0.19 THR 102 -0.38 ASP 70

ASN 197 0.21 VAL 103 -0.53 ASP 70

TYR 105 0.35 GLN 104 -0.74 ASP 70

GLN 104 0.35 TYR 105 -0.59 ASP 70

ASN 197 0.28 THR 106 -0.67 ASP 70

THR 24 0.31 ASP 107 -0.53 ASP 70

THR 24 0.36 SER 108 -0.57 ASP 70

THR 24 0.21 GLN 109 -0.53 ASP 70

GLN 104 0.30 ARG 110 -0.44 ASP 70

GLN 104 0.30 PRO 111 -0.35 ASP 70

GLN 104 0.22 ILE 112 -0.30 ASP 70

GLN 104 0.24 SER 113 -0.26 ASP 70

GLN 104 0.18 LEU 114 -0.31 PRO 23

GLN 104 0.16 PRO 115 -0.36 PRO 23

GLN 104 0.16 SER 116 -0.36 GLY 164

GLN 104 0.13 LYS 117 -0.45 GLY 164

GLN 104 0.17 GLY 118 -0.44 GLY 164

GLN 104 0.15 ASP 119 -0.38 PRO 23

ILE 123 0.17 ARG 120 -0.46 PRO 23

ILE 123 0.24 ASN 121 -0.45 PRO 23

THR 125 0.19 VAL 122 -0.40 PRO 23

ASN 121 0.24 ILE 123 -0.42 PRO 23

THR 125 0.17 TYR 124 -0.40 PRO 23

VAL 122 0.19 THR 125 -0.38 PRO 23

THR 24 0.23 ASP 126 -0.33 PRO 23

THR 24 0.23 CYS 127 -0.38 PRO 23

THR 24 0.29 TRP 128 -0.36 PRO 23

THR 24 0.30 VAL 129 -0.42 PRO 23

THR 24 0.38 THR 130 -0.33 PRO 23

THR 24 0.44 GLY 131 -0.32 PRO 23

THR 24 0.60 TRP 132 -0.27 PRO 23

THR 24 0.51 GLY 133 -0.46 PRO 23

THR 24 0.57 TYR 134 -0.53 PRO 23

THR 24 0.59 ARG 135 -0.49 PRO 23

GLY 164 0.51 LYS 136 -0.65 PRO 23

GLY 164 0.58 LEU 137 -0.82 PRO 23

GLY 164 0.47 ARG 138 -0.85 PRO 23

THR 24 0.59 ASP 139 -0.59 PRO 23

THR 24 0.73 LYS 140 -0.47 PRO 23

THR 24 0.76 ILE 141 -0.32 PRO 23

THR 24 0.85 GLN 142 -0.29 ILE 67

THR 24 1.04 ASN 143 -0.29 GLU 69

THR 24 0.84 THR 144 -0.36 GLU 69

THR 24 0.64 LEU 145 -0.34 GLU 69

THR 24 0.58 GLN 146 -0.27 GLU 69

THR 24 0.47 LYS 147 -0.28 PRO 23

THR 24 0.41 ALA 148 -0.36 PRO 23

THR 24 0.33 LYS 149 -0.38 PRO 23

THR 24 0.28 ILE 150 -0.47 PRO 23

THR 24 0.22 PRO 151 -0.49 PRO 23

THR 24 0.15 LEU 152 -0.54 PRO 23

THR 24 0.14 VAL 153 -0.59 PRO 23

THR 24 0.09 THR 154 -0.60 PRO 23

CYS 173 0.10 ASN 155 -0.65 PRO 23

LYS 136 0.12 GLU 156 -0.64 PRO 23

LYS 136 0.15 GLU 157 -0.65 PRO 23

ARG 163 0.15 CYS 158 -0.71 PRO 23

ARG 163 0.21 GLN 159 -0.73 PRO 23

LYS 136 0.20 LYS 160 -0.72 PRO 23

ARG 163 0.33 ARG 161 -0.77 PRO 23

ARG 163 0.40 TYR 162 -0.86 PRO 23

TYR 162 0.40 ARG 163 -0.85 PRO 23

GLY 211 0.63 GLY 164 -0.94 LYS 166

GLY 211 0.25 HIS 165 -0.88 PRO 23

GLU 89 0.23 LYS 166 -0.94 GLY 164

GLU 89 0.13 ILE 167 -0.78 PRO 23

SER 90 0.15 THR 168 -0.74 PRO 23

ILE 172 0.12 HIS 169 -0.67 PRO 23

ILE 172 0.10 LYS 170 -0.69 PRO 23

HIS 169 0.10 MET 171 -0.72 PRO 23

HIS 169 0.12 ILE 172 -0.66 PRO 23

THR 24 0.10 CYS 173 -0.67 PRO 23

THR 24 0.18 ALA 174 -0.61 PRO 23

THR 24 0.24 GLY 175 -0.61 PRO 23

THR 24 0.27 TYR 176 -0.57 PRO 23

GLY 179 0.31 ARG 177 -0.60 PRO 23

GLY 180 0.38 GLU 178 -0.58 PRO 23

GLY 164 0.38 GLY 179 -0.63 PRO 23

THR 24 0.40 GLY 180 -0.56 PRO 23

THR 24 0.39 LYS 181 -0.52 PRO 23

THR 24 0.34 ASP 182 -0.60 PRO 23

THR 24 0.33 ALA 183 -0.61 PRO 23

THR 24 0.35 CYS 184 -0.70 PRO 23

GLY 164 0.33 LYS 185 -0.76 PRO 23

VAL 49 0.33 GLY 186 -0.60 PRO 23

THR 24 0.30 ASP 187 -0.54 PRO 23

VAL 49 0.19 SER 188 -0.67 PRO 23

VAL 49 0.11 GLY 189 -0.56 PRO 23

THR 24 0.15 GLY 190 -0.43 PRO 23

THR 24 0.15 PRO 191 -0.41 PRO 23

THR 24 0.16 LEU 192 -0.45 PRO 23

THR 24 0.18 SER 193 -0.34 PRO 23

THR 24 0.18 CYS 194 -0.34 PRO 23

THR 24 0.19 LYS 195 -0.26 PRO 23

GLN 104 0.22 HIS 196 -0.27 PRO 23

VAL 199 0.40 ASN 197 -0.27 ILE 123

LYS 149 0.25 GLU 198 -0.46 VAL 199

ASN 197 0.40 VAL 199 -0.46 GLU 198

GLN 104 0.22 TRP 200 -0.26 ASP 70

GLN 104 0.20 HIS 201 -0.29 PRO 23

GLN 104 0.15 LEU 202 -0.36 PRO 23

GLN 104 0.12 VAL 203 -0.45 PRO 23

GLN 104 0.09 GLY 204 -0.54 PRO 23

GLY 35 0.08 ILE 205 -0.57 PRO 23

THR 24 0.10 THR 206 -0.65 PRO 23

ALA 237 0.11 SER 207 -0.82 PRO 23

HIS 165 0.17 TRP 208 -0.93 PRO 23

GLY 164 0.29 ALA 209 -0.91 PRO 23

GLY 164 0.56 GLU 210 -0.97 PRO 23

GLY 164 0.63 GLY 211 -0.92 PRO 23

GLY 164 0.51 CYS 212 -0.77 PRO 23

GLY 164 0.45 ALA 213 -0.68 PRO 23

ARG 215 0.73 GLN 214 -0.74 PRO 23

GLN 214 0.73 ARG 215 -0.63 PRO 23

GLY 164 0.42 GLU 216 -0.71 PRO 23

GLY 164 0.43 ARG 217 -0.78 PRO 23

GLY 164 0.22 PRO 218 -0.71 PRO 23

THR 24 0.18 ALA 219 -0.75 PRO 23

GLN 159 0.09 VAL 220 -0.78 PRO 23

GLY 35 0.07 TYR 221 -0.71 PRO 23

ALA 237 0.06 THR 222 -0.69 PRO 23

GLN 104 0.07 ASN 223 -0.61 PRO 23

GLN 104 0.08 VAL 224 -0.52 PRO 23

GLN 104 0.09 VAL 225 -0.49 PRO 23

LEU 152 0.07 GLU 226 -0.56 PRO 23

ASP 83 0.10 TYR 227 -0.53 PRO 23

ASP 229 0.15 VAL 228 -0.42 PRO 23

VAL 228 0.15 ASP 229 -0.47 GLY 164

ASP 83 0.14 TRP 230 -0.53 GLU 50

ASP 83 0.13 ILE 231 -0.45 GLU 50

GLU 233 0.17 LEU 232 -0.43 GLU 50

GLN 236 0.29 GLU 233 -0.53 GLU 50

GLN 236 0.30 LYS 234 -0.57 GLU 50

LYS 234 0.22 THR 235 -0.42 GLU 50

VAL 238 0.32 GLN 236 -0.94 ALA 237

ASP 83 0.48 ALA 237 -0.94 GLN 236

GLN 236 0.32 VAL 238 -0.48 GLU 50

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A-G226A ***

CA distance fluctuations for 2602061647033086323

--- normal mode 25 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *