Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *

CA distance fluctuations for 2602061647033086323

--- normal mode 28 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
THR 24 0.58 ILE 1 -0.58 PRO 23

THR 24 0.62 VAL 2 -0.59 ARG 138

THR 24 0.53 GLY 3 -0.66 ARG 138

THR 24 0.45 GLY 4 -0.62 ARG 138

THR 24 0.34 THR 5 -0.69 ARG 138

ARG 177 0.29 ALA 6 -0.64 ARG 138

ARG 177 0.27 SER 7 -0.51 ARG 138

GLU 198 0.27 VAL 8 -0.46 ARG 138

GLU 69 0.24 ARG 9 -0.38 ARG 138

GLU 69 0.30 GLY 10 -0.30 ARG 138

GLU 69 0.27 GLU 11 -0.33 ARG 138

GLU 69 0.29 TRP 12 -0.26 ARG 138

ASP 70 0.40 PRO 13 -0.20 ARG 138

ASP 70 0.43 TRP 14 -0.15 PRO 111

ASP 70 0.34 GLN 15 -0.22 PRO 23

ASP 70 0.38 VAL 16 -0.22 VAL 49

LEU 137 0.38 THR 17 -0.29 VAL 49

LEU 137 0.46 LEU 18 -0.35 VAL 49

LEU 137 0.53 HIS 19 -0.39 VAL 49

LEU 137 0.57 THR 20 -0.49 GLU 50

LEU 137 0.60 THR 21 -0.47 THR 24

LEU 137 0.56 SER 22 -0.59 GLU 69

LYS 53 0.63 PRO 23 -1.26 LYS 140

LEU 137 1.11 THR 24 -0.79 GLU 69

LEU 137 0.55 GLN 25 -0.58 GLU 69

LEU 137 0.65 ARG 26 -0.48 GLU 50

LEU 137 0.58 HIS 27 -0.51 VAL 49

LEU 137 0.69 LEU 28 -0.63 VAL 49

LEU 137 0.57 CYS 29 -0.49 PRO 23

LEU 137 0.41 GLY 30 -0.38 PRO 23

ASP 70 0.34 GLY 31 -0.27 LYS 140

ASP 70 0.40 SER 32 -0.20 LYS 140

ASP 70 0.48 ILE 33 -0.18 LYS 140

ASP 70 0.46 ILE 34 -0.18 LYS 140

ASP 70 0.52 GLY 35 -0.17 LYS 140

ASP 70 0.62 ASN 36 -0.17 THR 24

ASP 70 0.64 GLN 37 -0.20 THR 24

ASP 70 0.52 TRP 38 -0.22 LYS 140

ASP 70 0.49 ILE 39 -0.23 LYS 140

ASP 70 0.38 LEU 40 -0.26 LYS 140

LEU 137 0.34 THR 41 -0.32 LYS 140

LEU 137 0.42 ALA 42 -0.36 LYS 140

LEU 137 0.44 ALA 43 -0.36 LYS 140

LEU 137 0.54 HIS 44 -0.43 PRO 23

LEU 137 0.58 CYS 45 -0.49 LYS 140

LEU 137 0.51 PHE 46 -0.45 LYS 140

LEU 137 0.56 TYR 47 -0.49 LYS 140

LYS 86 0.50 GLY 48 -0.59 LYS 140

ASP 83 0.55 VAL 49 -0.70 LYS 140

ASP 83 0.85 GLU 50 -0.64 LYS 140

ASP 83 0.38 SER 51 -0.43 THR 24

LEU 137 0.37 PRO 52 -0.37 THR 24

PRO 23 0.63 LYS 53 -0.57 THR 24

LEU 137 0.47 ILE 54 -0.57 THR 24

LEU 137 0.48 LEU 55 -0.30 THR 24

LEU 137 0.45 ARG 56 -0.26 THR 24

ASP 70 0.45 VAL 57 -0.16 LYS 140

GLU 69 0.48 TYR 58 -0.18 SER 59

ASP 70 0.50 SER 59 -0.18 TYR 58

GLU 69 0.45 GLY 60 -0.19 SER 108

GLU 69 0.35 ILE 61 -0.23 VAL 49

ARG 177 0.26 LEU 62 -0.32 ARG 138

ARG 177 0.27 GLN 63 -0.32 ARG 138

ARG 177 0.27 GLN 64 -0.36 VAL 49

ARG 177 0.25 SER 65 -0.46 ASP 70

ARG 177 0.24 GLU 66 -0.29 ILE 67

LEU 137 0.33 ILE 67 -0.29 GLU 66

LEU 137 0.34 LYS 68 -0.64 ASP 70

THR 71 1.06 GLU 69 -0.79 THR 24

THR 101 0.93 ASP 70 -0.64 LYS 68

GLU 69 1.06 THR 71 -0.50 LYS 68

GLU 69 1.04 SER 72 -0.38 THR 24

ASP 70 0.74 PHE 73 -0.32 THR 24

ASP 70 0.77 PHE 74 -0.33 THR 24

ASP 70 0.71 GLY 75 -0.42 THR 24

ASP 70 0.55 VAL 76 -0.32 THR 24

ASP 70 0.57 GLN 77 -0.38 THR 24

GLU 50 0.48 GLU 78 -0.29 LYS 140

GLU 50 0.52 ILE 79 -0.33 LYS 140

GLU 50 0.58 ILE 80 -0.32 LYS 140

GLU 50 0.64 ILE 81 -0.32 LYS 140

GLU 50 0.57 HIS 82 -0.30 LYS 140

GLU 50 0.85 ASP 83 -0.23 LYS 140

GLU 50 0.69 GLN 84 -0.24 GLU 226

GLU 50 0.58 TYR 85 -0.28 LYS 140

GLU 50 0.57 LYS 86 -0.26 LYS 140

LEU 137 0.48 MET 87 -0.34 PRO 23

LEU 137 0.48 ALA 88 -0.40 PRO 23

THR 24 0.48 GLU 89 -0.40 PRO 23

THR 24 0.40 SER 90 -0.30 PRO 23

THR 24 0.35 GLY 91 -0.29 PRO 23

GLU 50 0.44 TYR 92 -0.25 LYS 140

LEU 137 0.38 ASP 93 -0.30 LYS 140

GLU 50 0.35 ILE 94 -0.30 LYS 140

GLU 50 0.37 ALA 95 -0.32 LYS 140

ASP 70 0.40 LEU 96 -0.29 LYS 140

ASP 70 0.46 LEU 97 -0.28 LYS 140

ASP 70 0.55 LYS 98 -0.23 LYS 140

ASP 70 0.68 LEU 99 -0.26 THR 24

ASP 70 0.79 GLU 100 -0.35 THR 24

ASP 70 0.93 THR 101 -0.32 THR 24

ASP 70 0.85 THR 102 -0.25 THR 24

ASP 70 0.80 VAL 103 -0.20 THR 24

ASP 70 0.77 GLN 104 -0.21 THR 24

ASP 70 0.60 TYR 105 -0.15 ILE 67

ASP 70 0.52 THR 106 -0.17 ILE 67

ASP 70 0.39 ASP 107 -0.23 ARG 138

ASP 70 0.40 SER 108 -0.22 ARG 138

ASP 70 0.54 GLN 109 -0.14 ARG 138

ASP 70 0.51 ARG 110 -0.12 ARG 138

ASP 70 0.47 PRO 111 -0.15 TRP 14

ASP 70 0.39 ILE 112 -0.13 LYS 140

ASP 70 0.37 SER 113 -0.23 GLU 198

ASP 70 0.35 LEU 114 -0.23 GLU 198

ASP 70 0.32 PRO 115 -0.27 GLU 198

ASP 70 0.31 SER 116 -0.28 GLU 198

ASP 70 0.28 LYS 117 -0.26 GLU 198

ASP 70 0.27 GLY 118 -0.26 GLU 198

ASP 70 0.29 ASP 119 -0.24 ASN 197

ASP 70 0.27 ARG 120 -0.20 GLN 84

ASP 70 0.25 ASN 121 -0.24 HIS 169

ASP 70 0.26 VAL 122 -0.23 HIS 169

THR 24 0.24 ILE 123 -0.26 HIS 169

THR 24 0.26 TYR 124 -0.24 PRO 23

THR 24 0.27 THR 125 -0.27 PRO 23

THR 24 0.26 ASP 126 -0.27 PRO 23

THR 24 0.29 CYS 127 -0.31 PRO 23

THR 24 0.32 TRP 128 -0.34 PRO 23

THR 24 0.38 VAL 129 -0.41 PRO 23

THR 24 0.37 THR 130 -0.41 PRO 23

THR 24 0.41 GLY 131 -0.50 PRO 23

THR 24 0.48 TRP 132 -0.60 PRO 23

THR 24 0.70 GLY 133 -0.70 PRO 23

THR 24 0.76 TYR 134 -0.83 PRO 23

THR 24 0.70 ARG 135 -0.77 ARG 138

THR 24 0.81 LYS 136 -0.79 ARG 138

THR 24 1.11 LEU 137 -0.53 LYS 136

THR 24 1.08 ARG 138 -0.79 LYS 136

THR 24 0.80 ASP 139 -1.05 PRO 23

THR 24 0.63 LYS 140 -1.26 PRO 23

THR 24 0.72 ILE 141 -0.87 PRO 23

THR 24 0.51 GLN 142 -0.71 PRO 23

THR 24 0.32 ASN 143 -0.57 PRO 23

ARG 177 0.30 THR 144 -0.49 ARG 138

THR 24 0.30 LEU 145 -0.44 PRO 23

THR 24 0.37 GLN 146 -0.52 ARG 138

THR 24 0.36 LYS 147 -0.46 ARG 138

ARG 177 0.41 ALA 148 -0.44 ARG 138

ARG 177 0.38 LYS 149 -0.37 PRO 23

ARG 177 0.43 ILE 150 -0.38 PRO 23

THR 24 0.39 PRO 151 -0.32 PRO 23

THR 24 0.37 LEU 152 -0.31 PRO 23

THR 24 0.41 VAL 153 -0.30 PRO 23

THR 24 0.38 THR 154 -0.27 PRO 23

THR 24 0.38 ASN 155 -0.27 PRO 23

THR 24 0.37 GLU 156 -0.28 PRO 23

THR 24 0.42 GLU 157 -0.30 PRO 23

THR 24 0.45 CYS 158 -0.34 PRO 23

THR 24 0.44 GLN 159 -0.32 PRO 23

THR 24 0.42 LYS 160 -0.37 PRO 23

THR 24 0.48 ARG 161 -0.40 PRO 23

THR 24 0.47 TYR 162 -0.43 PRO 23

THR 24 0.43 ARG 163 -0.41 PRO 23

THR 24 0.41 GLY 164 -0.47 PRO 23

THR 24 0.47 HIS 165 -0.37 PRO 23

THR 24 0.42 LYS 166 -0.30 PRO 23

THR 24 0.41 ILE 167 -0.30 PRO 23

THR 24 0.35 THR 168 -0.24 PRO 23

THR 24 0.29 HIS 169 -0.26 ILE 123

GLU 50 0.32 LYS 170 -0.24 ILE 123

THR 24 0.36 MET 171 -0.28 PRO 23

THR 24 0.37 ILE 172 -0.29 PRO 23

THR 24 0.44 CYS 173 -0.34 PRO 23

THR 24 0.45 ALA 174 -0.36 PRO 23

THR 24 0.50 GLY 175 -0.39 PRO 23

ARG 177 0.96 TYR 176 -0.37 PRO 23

TYR 176 0.96 ARG 177 -0.33 PRO 23

THR 24 0.58 GLU 178 -0.35 PRO 23

THR 24 0.59 GLY 179 -0.42 PRO 23

THR 24 0.60 GLY 180 -0.45 PRO 23

THR 24 0.54 LYS 181 -0.47 PRO 23

THR 24 0.58 ASP 182 -0.50 PRO 23

THR 24 0.60 ALA 183 -0.55 PRO 23

THR 24 0.73 CYS 184 -0.68 PRO 23

LEU 137 0.93 LYS 185 -0.82 PRO 23

THR 24 0.75 GLY 186 -0.75 PRO 23

THR 24 0.57 ASP 187 -0.59 PRO 23

LEU 137 0.53 SER 188 -0.55 PRO 23

LEU 137 0.40 GLY 189 -0.39 PRO 23

THR 24 0.34 GLY 190 -0.37 PRO 23

ASP 70 0.30 PRO 191 -0.31 PRO 23

THR 24 0.31 LEU 192 -0.33 PRO 23

ASP 70 0.28 SER 193 -0.27 PRO 23

ASP 70 0.26 CYS 194 -0.25 PRO 23

ASP 70 0.27 LYS 195 -0.22 PRO 23

ASP 70 0.27 HIS 196 -0.19 PRO 23

ASP 70 0.30 ASN 197 -0.25 GLY 118

ASP 70 0.30 GLU 198 -0.42 VAL 199

ASP 70 0.31 VAL 199 -0.42 GLU 198

ASP 70 0.31 TRP 200 -0.18 PRO 23

ASP 70 0.32 HIS 201 -0.20 GLU 198

ASP 70 0.32 LEU 202 -0.22 PRO 23

ASP 70 0.29 VAL 203 -0.24 PRO 23

THR 24 0.29 GLY 204 -0.30 PRO 23

THR 24 0.32 ILE 205 -0.33 PRO 23

THR 24 0.44 THR 206 -0.43 PRO 23

THR 24 0.49 SER 207 -0.44 PRO 23

THR 24 0.58 TRP 208 -0.52 PRO 23

THR 24 0.63 ALA 209 -0.54 PRO 23

THR 24 0.65 GLU 210 -0.58 PRO 23

THR 24 0.75 GLY 211 -0.64 PRO 23

THR 24 0.73 CYS 212 -0.60 PRO 23

THR 24 0.67 ALA 213 -0.51 PRO 23

THR 24 0.64 GLN 214 -0.51 PRO 23

THR 24 0.63 ARG 215 -0.40 PRO 23

THR 24 0.55 GLU 216 -0.41 PRO 23

THR 24 0.57 ARG 217 -0.46 PRO 23

THR 24 0.54 PRO 218 -0.42 PRO 23

THR 24 0.55 ALA 219 -0.45 PRO 23

THR 24 0.49 VAL 220 -0.40 PRO 23

THR 24 0.41 TYR 221 -0.36 PRO 23

THR 24 0.33 THR 222 -0.29 PRO 23

ASN 155 0.27 ASN 223 -0.25 PRO 23

ASP 70 0.31 VAL 224 -0.20 PRO 23

ASP 70 0.30 VAL 225 -0.22 GLU 198

GLU 50 0.29 GLU 226 -0.24 GLN 84

GLU 50 0.33 TYR 227 -0.20 GLU 198

ASP 70 0.32 VAL 228 -0.23 GLU 198

GLU 50 0.33 ASP 229 -0.24 GLU 198

GLU 50 0.40 TRP 230 -0.22 LYS 140

ASP 70 0.36 ILE 231 -0.22 LYS 140

ASP 70 0.35 LEU 232 -0.20 LYS 140

GLU 50 0.39 GLU 233 -0.21 LYS 140

GLU 50 0.42 LYS 234 -0.24 LYS 140

ASP 70 0.43 THR 235 -0.22 LYS 140

ALA 237 1.02 GLN 236 -0.20 LYS 140

GLN 236 1.02 ALA 237 -0.23 LYS 140

ASP 70 0.47 VAL 238 -0.20 GLN 236

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A-G226A ***

CA distance fluctuations for 2602061647033086323

--- normal mode 28 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *