Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A *

CA distance fluctuations for 2602071232343282027

--- normal mode 18 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASN 121 0.21 ILE 1 -0.59 PRO 23

ASN 121 0.25 VAL 2 -0.61 PRO 23

ASN 121 0.24 GLY 3 -0.52 PRO 23

ASN 121 0.19 GLY 4 -0.46 PRO 23

ASN 121 0.12 THR 5 -0.37 ARG 26

GLY 190 0.09 ALA 6 -0.37 GLU 198

GLY 190 0.09 SER 7 -0.45 GLU 198

CYS 45 0.07 VAL 8 -0.52 GLU 198

THR 24 0.10 ARG 9 -0.53 GLU 198

THR 24 0.11 GLY 10 -0.59 GLU 198

PRO 13 0.08 GLU 11 -0.61 GLU 198

PRO 13 0.09 TRP 12 -0.44 GLU 198

TRP 12 0.09 PRO 13 -0.37 GLU 198

GLU 50 0.10 TRP 14 -0.24 GLY 118

SER 32 0.10 GLN 15 -0.29 GLU 198

SER 108 0.12 VAL 16 -0.25 THR 17

GLY 186 0.14 THR 17 -0.27 GLU 198

GLY 48 0.08 LEU 18 -0.21 GLY 190

GLU 69 0.20 HIS 19 -0.31 LYS 140

GLU 69 0.37 THR 20 -0.52 CYS 45

ASP 70 0.54 THR 21 -0.72 LYS 140

GLU 69 0.62 SER 22 -0.91 TYR 47

ASP 70 0.84 PRO 23 -0.92 MET 87

ASP 70 1.13 THR 24 -0.93 ASP 139

GLU 69 1.02 GLN 25 -0.86 LYS 140

GLU 69 0.78 ARG 26 -0.96 ILE 141

GLU 69 0.33 HIS 27 -0.53 ARG 26

GLU 69 0.25 LEU 28 -0.64 CYS 29

CYS 45 0.15 CYS 29 -0.64 LEU 28

GLY 186 0.20 GLY 30 -0.53 GLY 190

GLU 50 0.15 GLY 31 -0.33 LEU 28

GLU 50 0.15 SER 32 -0.23 LEU 28

GLU 50 0.14 ILE 33 -0.25 SER 116

GLU 50 0.17 ILE 34 -0.32 SER 116

GLU 50 0.15 GLY 35 -0.32 GLY 118

THR 24 0.21 ASN 36 -0.29 GLY 118

THR 24 0.18 GLN 37 -0.28 ASP 70

GLU 50 0.18 TRP 38 -0.23 SER 72

GLU 50 0.19 ILE 39 -0.21 SER 72

GLU 50 0.24 LEU 40 -0.30 PRO 23

GLU 50 0.25 THR 41 -0.43 PRO 23

GLU 50 0.30 ALA 42 -0.61 PRO 23

GLU 50 0.43 ALA 43 -0.65 PRO 23

GLU 50 0.34 HIS 44 -0.87 PRO 23

GLY 211 0.26 CYS 45 -0.80 SER 22

GLU 50 0.32 PHE 46 -0.73 SER 22

GLY 211 0.29 TYR 47 -0.91 SER 22

GLY 211 0.22 GLY 48 -0.86 SER 22

GLY 48 0.21 VAL 49 -0.67 SER 22

ILE 81 0.57 GLU 50 -0.53 SER 22

ILE 81 0.22 SER 51 -0.20 GLU 69

LYS 53 0.21 PRO 52 -0.21 ASP 70

GLN 77 0.30 LYS 53 -0.43 GLU 69

GLN 77 0.17 ILE 54 -0.39 GLU 50

GLY 75 0.20 LEU 55 -0.28 VAL 49

THR 24 0.27 ARG 56 -0.31 LYS 53

THR 24 0.23 VAL 57 -0.17 SER 116

THR 24 0.28 TYR 58 -0.21 GLU 198

THR 24 0.26 SER 59 -0.27 GLU 198

THR 24 0.26 GLY 60 -0.35 GLU 198

THR 24 0.19 ILE 61 -0.36 GLU 198

GLY 186 0.13 LEU 62 -0.40 GLU 198

GLY 186 0.15 GLN 63 -0.35 GLU 198

GLY 186 0.16 GLN 64 -0.30 GLU 198

THR 24 0.19 SER 65 -0.29 GLU 198

THR 24 0.36 GLU 66 -0.32 GLU 198

THR 24 0.46 ILE 67 -0.34 LYS 53

THR 24 0.73 LYS 68 -0.37 LYS 53

THR 24 1.09 GLU 69 -0.43 LYS 53

THR 24 1.13 ASP 70 -0.41 THR 101

THR 24 0.82 THR 71 -0.34 PHE 73

THR 24 0.78 SER 72 -0.38 THR 101

THR 24 0.53 PHE 73 -0.40 ASP 70

THR 24 0.43 PHE 74 -0.37 SER 72

THR 21 0.45 GLY 75 -0.37 ASP 70

THR 21 0.23 VAL 76 -0.26 ASP 70

LYS 53 0.30 GLN 77 -0.29 ASP 70

GLU 50 0.31 GLU 78 -0.22 ASP 70

GLU 50 0.43 ILE 79 -0.22 SER 22

GLU 50 0.49 ILE 80 -0.28 PRO 23

GLU 50 0.57 ILE 81 -0.44 PRO 23

GLU 50 0.49 HIS 82 -0.47 PRO 23

GLU 50 0.52 ASP 83 -0.48 PRO 23

GLU 50 0.45 GLN 84 -0.57 PRO 23

GLU 50 0.50 TYR 85 -0.66 PRO 23

GLU 50 0.49 LYS 86 -0.78 PRO 23

GLU 50 0.41 MET 87 -0.92 PRO 23

ASN 121 0.37 ALA 88 -0.90 PRO 23

ASN 121 0.43 GLU 89 -0.89 PRO 23

ASN 121 0.45 SER 90 -0.80 PRO 23

ASN 121 0.47 GLY 91 -0.72 PRO 23

ASN 121 0.40 TYR 92 -0.63 PRO 23

GLU 50 0.37 ASP 93 -0.68 PRO 23

GLU 50 0.36 ILE 94 -0.55 PRO 23

GLU 50 0.38 ALA 95 -0.43 PRO 23

GLU 50 0.31 LEU 96 -0.28 PRO 23

GLU 50 0.26 LEU 97 -0.19 SER 72

GLU 50 0.22 LYS 98 -0.24 ASP 70

THR 24 0.23 LEU 99 -0.31 SER 72

THR 24 0.34 GLU 100 -0.38 ASP 70

THR 24 0.40 THR 101 -0.41 ASP 70

THR 24 0.34 THR 102 -0.34 ASP 70

THR 24 0.35 VAL 103 -0.28 ASP 70

THR 24 0.40 GLN 104 -0.33 GLY 118

THR 24 0.32 TYR 105 -0.37 GLY 118

THR 24 0.34 THR 106 -0.40 GLU 198

THR 24 0.25 ASP 107 -0.55 GLU 198

THR 24 0.26 SER 108 -0.46 GLU 198

THR 24 0.23 GLN 109 -0.33 GLU 198

THR 24 0.16 ARG 110 -0.36 GLY 118

GLU 50 0.12 PRO 111 -0.34 GLY 118

GLU 50 0.14 ILE 112 -0.33 SER 113

ASN 197 0.26 SER 113 -0.35 GLY 118

ASN 197 0.37 LEU 114 -0.43 PRO 115

ASN 197 0.53 PRO 115 -0.43 LEU 114

ASN 197 0.67 SER 116 -0.37 LEU 114

ASN 197 0.52 LYS 117 -0.31 PRO 23

ASN 197 0.45 GLY 118 -0.37 TYR 105

HIS 169 0.40 ASP 119 -0.32 ASP 107

HIS 169 0.59 ARG 120 -0.32 PRO 23

HIS 169 0.92 ASN 121 -0.27 ASP 107

HIS 169 0.54 VAL 122 -0.32 ASP 107

ILE 172 0.28 ILE 123 -0.34 PRO 23

GLU 50 0.16 TYR 124 -0.36 PRO 23

GLU 50 0.13 THR 125 -0.38 ARG 177

GLU 50 0.11 ASP 126 -0.42 ARG 177

ASN 121 0.15 CYS 127 -0.41 PRO 23

ASN 121 0.14 TRP 128 -0.43 PRO 23

ASN 121 0.17 VAL 129 -0.49 PRO 23

LYS 147 0.11 THR 130 -0.46 ARG 26

CYS 45 0.13 GLY 131 -0.50 ARG 26

GLY 186 0.19 TRP 132 -0.64 ARG 26

ASN 121 0.14 GLY 133 -0.76 ARG 26

ASN 121 0.18 TYR 134 -0.74 THR 24

ASN 121 0.21 ARG 135 -0.64 THR 24

ARG 215 0.29 LYS 136 -0.75 THR 24

ARG 215 0.30 LEU 137 -0.86 THR 24

ARG 215 0.24 ARG 138 -0.90 THR 24

ARG 215 0.22 ASP 139 -0.93 THR 24

ARG 215 0.14 LYS 140 -0.92 THR 24

SER 65 0.14 ILE 141 -0.96 ARG 26

GLY 186 0.12 GLN 142 -0.66 ARG 26

GLY 186 0.14 ASN 143 -0.42 ARG 26

GLY 186 0.11 THR 144 -0.35 ARG 26

GLY 186 0.10 LEU 145 -0.40 ARG 26

GLY 190 0.11 GLN 146 -0.44 ARG 26

VAL 129 0.12 LYS 147 -0.41 ARG 26

ASN 121 0.17 ALA 148 -0.46 PRO 23

ASN 121 0.18 LYS 149 -0.44 PRO 23

ASN 121 0.27 ILE 150 -0.51 PRO 23

ASN 121 0.29 PRO 151 -0.49 PRO 23

ASN 121 0.44 LEU 152 -0.50 PRO 23

ASN 121 0.45 VAL 153 -0.55 PRO 23

ASN 121 0.56 THR 154 -0.55 PRO 23

ASN 121 0.72 ASN 155 -0.59 PRO 23

ASN 121 0.54 GLU 156 -0.56 PRO 23

ASN 121 0.40 GLU 157 -0.57 PRO 23

ASN 121 0.50 CYS 158 -0.63 PRO 23

ASN 121 0.51 GLN 159 -0.65 PRO 23

ASN 121 0.37 LYS 160 -0.61 PRO 23

ASN 121 0.36 ARG 161 -0.65 PRO 23

ASN 121 0.43 TYR 162 -0.71 PRO 23

ASN 121 0.40 ARG 163 -0.68 PRO 23

ASN 121 0.40 GLY 164 -0.73 PRO 23

ASN 121 0.48 HIS 165 -0.78 PRO 23

ASN 121 0.56 LYS 166 -0.72 PRO 23

ASN 121 0.64 ILE 167 -0.69 PRO 23

ASN 121 0.74 THR 168 -0.64 PRO 23

ASN 121 0.92 HIS 169 -0.56 PRO 23

ASN 121 0.68 LYS 170 -0.57 PRO 23

ASN 121 0.68 MET 171 -0.64 PRO 23

ASN 121 0.69 ILE 172 -0.60 PRO 23

ASN 121 0.58 CYS 173 -0.63 PRO 23

ASN 121 0.43 ALA 174 -0.59 PRO 23

ASN 121 0.37 GLY 175 -0.59 PRO 23

ASN 121 0.30 TYR 176 -0.57 ARG 177

ASN 121 0.24 ARG 177 -0.57 TYR 176

LYS 136 0.27 GLU 178 -0.50 PRO 23

ASN 121 0.29 GLY 179 -0.56 PRO 23

ASN 121 0.27 GLY 180 -0.55 PRO 23

ASN 121 0.28 LYS 181 -0.56 PRO 23

ASN 121 0.31 ASP 182 -0.63 PRO 23

ASN 121 0.26 ALA 183 -0.68 PRO 23

ASN 121 0.25 CYS 184 -0.79 PRO 23

CYS 45 0.22 LYS 185 -0.88 PRO 23

GLY 30 0.20 GLY 186 -0.76 PRO 23

CYS 45 0.15 ASP 187 -0.65 PRO 23

CYS 45 0.24 SER 188 -0.72 PRO 23

SER 188 0.22 GLY 189 -0.56 PRO 23

CYS 212 0.14 GLY 190 -0.53 GLY 30

GLU 50 0.14 PRO 191 -0.43 PRO 23

ASN 121 0.16 LEU 192 -0.46 PRO 23

GLU 50 0.12 SER 193 -0.38 PRO 23

GLU 50 0.13 CYS 194 -0.36 PRO 23

PRO 115 0.17 LYS 195 -0.32 PRO 23

SER 116 0.33 HIS 196 -0.37 ASP 107

SER 116 0.67 ASN 197 -0.43 GLU 11

SER 116 0.38 GLU 198 -0.61 GLU 11

LEU 232 0.23 VAL 199 -0.45 ASP 107

LEU 232 0.18 TRP 200 -0.33 ASP 107

ILE 231 0.19 HIS 201 -0.29 PRO 23

GLU 50 0.20 LEU 202 -0.33 PRO 23

GLU 50 0.20 VAL 203 -0.41 PRO 23

ASN 121 0.26 GLY 204 -0.49 PRO 23

ASN 121 0.24 ILE 205 -0.55 PRO 23

ASN 121 0.26 THR 206 -0.66 PRO 23

ASN 121 0.35 SER 207 -0.80 PRO 23

ASN 121 0.38 TRP 208 -0.91 PRO 23

ASN 121 0.40 ALA 209 -0.87 PRO 23

ASN 121 0.35 GLU 210 -0.85 PRO 23

ASN 121 0.34 GLY 211 -0.83 PRO 23

ASN 121 0.33 CYS 212 -0.76 PRO 23

ASN 121 0.31 ALA 213 -0.65 PRO 23

ASN 121 0.31 GLN 214 -0.64 PRO 23

LEU 137 0.30 ARG 215 -0.56 PRO 23

ASN 121 0.29 GLU 216 -0.60 PRO 23

ASN 121 0.36 ARG 217 -0.68 PRO 23

ASN 121 0.41 PRO 218 -0.68 PRO 23

ASN 121 0.41 GLY 219 -0.73 PRO 23

ASN 121 0.49 VAL 220 -0.74 PRO 23

ASN 121 0.44 TYR 221 -0.67 PRO 23

ASN 121 0.43 THR 222 -0.61 PRO 23

ASN 121 0.49 ASN 223 -0.52 PRO 23

ASN 197 0.29 VAL 224 -0.44 PRO 23

ASN 197 0.38 VAL 225 -0.39 PRO 23

ASN 121 0.34 GLU 226 -0.42 PRO 23

ASN 197 0.35 TYR 227 -0.41 PRO 23

ASN 197 0.44 VAL 228 -0.33 PRO 23

ASN 197 0.44 ASP 229 -0.30 PRO 23

ASN 197 0.37 TRP 230 -0.32 PRO 23

ASN 197 0.35 ILE 231 -0.28 PRO 23

ASN 197 0.41 LEU 232 -0.21 PRO 23

ASN 197 0.37 GLU 233 -0.20 PRO 23

GLU 50 0.32 LYS 234 -0.19 PRO 23

ASN 197 0.29 THR 235 -0.21 ASP 70

ASN 197 0.31 GLN 236 -0.21 ASP 70

GLU 50 0.32 ALA 237 -0.22 ASP 70

GLU 50 0.32 VAL 238 -0.26 ASP 70

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A ***

CA distance fluctuations for 2602071232343282027

--- normal mode 18 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A *