Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A *

CA distance fluctuations for 2602071232343282027

--- normal mode 26 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASN 121 0.33 ILE 1 -0.32 GLY 131

ASN 121 0.28 VAL 2 -0.32 ARG 215

ASN 121 0.24 GLY 3 -0.28 GLY 180

ASN 197 0.29 GLY 4 -0.27 GLN 109

ASN 197 0.37 THR 5 -0.23 GLN 104

ASN 197 0.40 ALA 6 -0.23 GLN 104

GLU 198 0.48 SER 7 -0.26 GLN 104

GLU 198 0.52 VAL 8 -0.26 GLN 104

GLU 198 0.51 ARG 9 -0.26 GLN 104

GLU 198 0.55 GLY 10 -0.32 SER 108

GLU 198 0.66 GLU 11 -0.43 ASP 107

GLU 198 0.56 TRP 12 -0.46 PRO 13

GLU 198 0.45 PRO 13 -0.46 TRP 12

GLU 198 0.40 TRP 14 -0.39 ASP 182

GLU 198 0.49 GLN 15 -0.39 ALA 183

THR 17 0.55 VAL 16 -0.37 ALA 209

VAL 16 0.55 THR 17 -0.39 GLY 186

ASN 121 0.40 LEU 18 -0.35 GLY 211

ASN 121 0.41 HIS 19 -0.27 GLY 211

ASN 121 0.41 THR 20 -0.20 GLU 210

ASN 121 0.38 THR 21 -0.13 GLU 210

LYS 68 0.43 SER 22 -0.16 PRO 23

LYS 68 0.57 PRO 23 -0.16 SER 22

LYS 68 0.81 THR 24 -0.14 TYR 47

LYS 68 0.72 GLN 25 -0.16 GLU 210

LYS 68 0.71 ARG 26 -0.21 GLU 210

GLU 198 0.41 HIS 27 -0.28 GLY 211

ASN 121 0.45 LEU 28 -0.31 GLY 211

ASN 121 0.45 CYS 29 -0.40 GLY 211

PRO 191 0.52 GLY 30 -0.41 GLY 211

LEU 18 0.40 GLY 31 -0.47 ALA 209

GLU 198 0.36 SER 32 -0.46 ALA 209

VAL 57 0.33 ILE 33 -0.45 SER 207

SER 113 0.26 ILE 34 -0.47 ILE 205

GLU 198 0.20 GLY 35 -0.43 SER 207

GLU 198 0.16 ASN 36 -0.38 ALA 209

ASN 121 0.18 GLN 37 -0.38 ALA 209

ASN 121 0.24 TRP 38 -0.45 SER 207

ASN 121 0.33 ILE 39 -0.46 SER 207

ASN 121 0.41 LEU 40 -0.55 SER 207

ASN 121 0.54 THR 41 -0.53 SER 207

ASN 121 0.60 ALA 42 -0.51 SER 207

ASN 121 0.60 ALA 43 -0.34 GLU 210

TYR 47 0.63 HIS 44 -0.36 GLU 210

ASN 121 0.56 CYS 45 -0.33 GLY 211

SER 51 0.53 PHE 46 -0.23 GLY 211

HIS 44 0.63 TYR 47 -0.22 GLU 78

ASN 121 0.49 GLY 48 -0.31 GLU 78

PHE 46 0.52 VAL 49 -0.30 GLU 78

ASN 121 0.46 GLU 50 -0.34 GLU 78

PHE 46 0.53 SER 51 -0.41 ASP 70

ASN 121 0.42 PRO 52 -0.42 ASP 70

ASN 121 0.39 LYS 53 -0.65 ASP 70

ASN 121 0.39 ILE 54 -0.40 ASP 70

ASN 121 0.39 LEU 55 -0.28 ASP 70

GLU 198 0.34 ARG 56 -0.28 GLY 211

GLU 198 0.36 VAL 57 -0.36 GLY 211

SER 59 0.43 TYR 58 -0.33 GLY 211

TYR 58 0.43 SER 59 -0.34 ALA 209

GLU 198 0.38 GLY 60 -0.33 VAL 103

GLU 198 0.45 ILE 61 -0.30 THR 101

GLU 198 0.47 LEU 62 -0.26 VAL 103

GLU 198 0.42 GLN 63 -0.24 TYR 58

ARG 26 0.41 GLN 64 -0.28 TYR 58

ARG 26 0.41 SER 65 -0.30 PHE 73

ASP 70 0.46 GLU 66 -0.32 PHE 73

ARG 26 0.67 ILE 67 -0.46 PHE 73

THR 24 0.81 LYS 68 -0.38 THR 71

THR 24 0.46 GLU 69 -0.27 SER 65

GLU 66 0.46 ASP 70 -0.65 LYS 53

ARG 26 0.37 THR 71 -0.40 LYS 53

GLU 198 0.29 SER 72 -0.55 THR 101

GLU 198 0.30 PHE 73 -0.46 ILE 67

GLU 198 0.25 PHE 74 -0.41 SER 72

ASN 121 0.26 GLY 75 -0.55 SER 72

ASN 121 0.31 VAL 76 -0.37 SER 72

ASN 121 0.29 GLN 77 -0.42 ASP 70

ASN 121 0.35 GLU 78 -0.34 GLU 50

ASN 121 0.43 ILE 79 -0.27 GLU 210

ASN 121 0.45 ILE 80 -0.30 GLU 210

ASN 121 0.51 ILE 81 -0.30 GLY 164

ASN 121 0.56 HIS 82 -0.32 GLY 164

ASN 121 0.53 ASP 83 -0.28 GLY 164

ASN 121 0.57 GLN 84 -0.32 GLY 164

ASN 121 0.58 TYR 85 -0.36 GLY 164

ASN 121 0.54 LYS 86 -0.36 GLY 164

ASN 121 0.53 MET 87 -0.41 GLY 164

ASN 121 0.57 ALA 88 -0.41 GLY 164

ASN 121 0.50 GLU 89 -0.44 GLY 164

ASN 121 0.55 SER 90 -0.48 GLY 164

ASN 121 0.66 GLY 91 -0.46 GLY 164

ASN 121 0.68 TYR 92 -0.36 GLY 164

ASN 121 0.66 ASP 93 -0.41 ALA 209

ASN 121 0.61 ILE 94 -0.38 ALA 209

ASN 121 0.54 ALA 95 -0.43 SER 207

ASN 121 0.44 LEU 96 -0.39 SER 207

ASN 121 0.38 LEU 97 -0.39 ALA 209

ASN 121 0.30 LYS 98 -0.34 ALA 209

ASN 121 0.24 LEU 99 -0.39 SER 72

ASN 121 0.20 GLU 100 -0.52 SER 72

ASN 121 0.14 THR 101 -0.55 SER 72

GLU 198 0.12 THR 102 -0.36 SER 72

GLU 198 0.16 VAL 103 -0.37 ALA 209

PHE 73 0.18 GLN 104 -0.34 ALA 209

PHE 73 0.26 TYR 105 -0.32 ALA 209

PHE 73 0.28 THR 106 -0.33 GLU 11

ASP 70 0.28 ASP 107 -0.43 GLU 11

GLU 198 0.33 SER 108 -0.35 GLU 11

TYR 58 0.39 GLN 109 -0.37 TRP 12

TYR 58 0.32 ARG 110 -0.35 ALA 209

GLU 198 0.30 PRO 111 -0.36 ALA 209

GLU 198 0.33 ILE 112 -0.36 GLY 219

HIS 19 0.33 SER 113 -0.28 CYS 173

THR 41 0.37 LEU 114 -0.30 CYS 173

THR 41 0.40 PRO 115 -0.28 CYS 173

THR 41 0.32 SER 116 -0.31 ASN 197

ASP 229 0.34 LYS 117 -0.27 ASN 155

SER 51 0.30 GLY 118 -0.33 ASN 197

ALA 42 0.36 ASP 119 -0.40 ASN 197

TYR 227 0.51 ARG 120 -0.30 ASN 197

HIS 169 0.94 ASN 121 -0.48 ASN 197

ASN 223 0.50 VAL 122 -0.51 ASN 197

HIS 169 0.50 ILE 123 -0.35 GLU 198

TYR 47 0.37 TYR 124 -0.22 GLU 198

TYR 47 0.33 THR 125 -0.19 GLU 198

TYR 47 0.31 ASP 126 -0.20 ASP 107

TYR 47 0.34 CYS 127 -0.27 ASP 107

GLY 131 0.39 TRP 128 -0.30 ASP 107

ASN 121 0.38 VAL 129 -0.38 TRP 14

GLY 131 0.59 THR 130 -0.36 ASP 182

THR 130 0.59 GLY 131 -0.34 ALA 213

GLU 198 0.36 TRP 132 -0.28 ALA 213

ASN 121 0.37 GLY 133 -0.32 THR 17

ASN 121 0.32 TYR 134 -0.33 ARG 215

ASN 121 0.27 ARG 135 -0.33 ARG 215

PRO 23 0.24 LYS 136 -0.46 ARG 215

ASN 121 0.22 LEU 137 -0.46 ARG 215

LYS 68 0.32 ARG 138 -0.42 ARG 215

LYS 68 0.33 ASP 139 -0.35 ARG 215

LYS 68 0.40 LYS 140 -0.29 ARG 215

PRO 23 0.37 ILE 141 -0.25 ARG 215

SER 65 0.35 GLN 142 -0.22 ARG 215

GLU 198 0.36 ASN 143 -0.25 TYR 58

GLU 198 0.41 THR 144 -0.22 THR 102

GLU 198 0.41 LEU 145 -0.28 VAL 103

ASN 197 0.38 GLN 146 -0.25 VAL 103

GLN 146 0.38 LYS 147 -0.32 PRO 13

ASN 197 0.29 ALA 148 -0.30 ASP 107

GLY 48 0.27 LYS 149 -0.30 ASP 107

ASN 121 0.29 ILE 150 -0.27 ASP 107

TYR 47 0.29 PRO 151 -0.24 SER 193

ASN 121 0.38 LEU 152 -0.24 ILE 112

ASN 121 0.31 VAL 153 -0.29 VAL 203

ASN 121 0.35 THR 154 -0.27 VAL 225

ASN 121 0.47 ASN 155 -0.29 VAL 225

ASN 121 0.34 GLU 156 -0.22 ILE 34

ASN 121 0.27 GLU 157 -0.26 ILE 34

ASN 121 0.34 CYS 158 -0.32 ILE 34

ASN 121 0.34 GLN 159 -0.28 ILE 34

ASN 121 0.27 LYS 160 -0.27 ILE 34

ASN 121 0.25 ARG 161 -0.32 ILE 34

ASN 121 0.29 TYR 162 -0.33 ILE 34

ASN 121 0.31 ARG 163 -0.29 LEU 137

ASN 121 0.25 GLY 164 -0.53 HIS 165

ASN 121 0.35 HIS 165 -0.53 GLY 164

ASN 121 0.40 LYS 166 -0.32 ASP 229

ASN 121 0.50 ILE 167 -0.29 ASP 229

ASN 121 0.63 THR 168 -0.32 ASP 229

ASN 121 0.94 HIS 169 -0.32 THR 168

ASN 121 0.90 LYS 170 -0.33 ASP 229

ASN 121 0.74 MET 171 -0.41 ASN 223

ASN 121 0.73 ILE 172 -0.34 ASN 223

ASN 121 0.46 CYS 173 -0.38 GLY 204

ASN 121 0.36 ALA 174 -0.35 LEU 202

ASN 121 0.27 GLY 175 -0.34 SER 193

ASN 121 0.22 TYR 176 -0.27 TRP 14

ASN 121 0.22 ARG 177 -0.27 ILE 33

ASN 121 0.19 GLU 178 -0.34 LYS 136

ASN 121 0.20 GLY 179 -0.32 ILE 33

ASN 121 0.21 GLY 180 -0.30 TRP 14

ASN 121 0.24 LYS 181 -0.32 TRP 14

ASN 121 0.30 ASP 182 -0.39 TRP 14

ASN 121 0.37 ALA 183 -0.40 SER 32

ASN 121 0.34 CYS 184 -0.42 CYS 212

ASN 121 0.37 LYS 185 -0.46 GLY 211

ASN 121 0.39 GLY 186 -0.39 THR 17

ASN 121 0.42 ASP 187 -0.39 CYS 212

ASN 121 0.48 SER 188 -0.48 ALA 209

CYS 45 0.55 GLY 189 -0.51 ALA 209

GLY 30 0.50 GLY 190 -0.47 ALA 209

GLY 30 0.52 PRO 191 -0.40 GLY 219

ASN 121 0.45 LEU 192 -0.37 PRO 218

GLY 30 0.50 SER 193 -0.34 GLY 175

GLY 30 0.38 CYS 194 -0.25 GLY 175

GLY 30 0.42 LYS 195 -0.16 VAL 199

GLY 30 0.35 HIS 196 -0.37 GLU 198

GLU 11 0.51 ASN 197 -0.51 VAL 122

GLU 11 0.66 GLU 198 -0.37 VAL 122

THR 17 0.34 VAL 199 -0.16 ALA 174

GLN 15 0.40 TRP 200 -0.21 GLY 175

GLY 30 0.38 HIS 201 -0.29 CYS 173

THR 41 0.48 LEU 202 -0.37 CYS 173

ASN 121 0.52 VAL 203 -0.38 CYS 173

ASN 121 0.58 GLY 204 -0.38 CYS 173

ASN 121 0.59 ILE 205 -0.47 ILE 34

ASN 121 0.53 THR 206 -0.50 ALA 209

ASN 121 0.52 SER 207 -0.55 LEU 40

ASN 121 0.44 TRP 208 -0.65 ALA 209

ASN 121 0.34 ALA 209 -0.65 TRP 208

ASN 121 0.29 GLU 210 -0.46 ALA 42

ASN 121 0.24 GLY 211 -0.48 SER 188

ASN 121 0.25 CYS 212 -0.42 CYS 184

ASN 121 0.24 ALA 213 -0.38 ILE 33

ASN 121 0.22 GLN 214 -0.48 ARG 215

ASN 121 0.19 ARG 215 -0.48 GLN 214

ASN 121 0.21 GLU 216 -0.34 LEU 137

ASN 121 0.26 ARG 217 -0.38 ILE 33

ASN 121 0.29 PRO 218 -0.39 ILE 33

ASN 121 0.37 GLY 219 -0.41 ILE 33

ASN 121 0.48 VAL 220 -0.48 TYR 221

ASN 121 0.61 TYR 221 -0.48 VAL 220

ASN 121 0.72 THR 222 -0.40 ILE 34

ASN 121 0.84 ASN 223 -0.41 MET 171

ASN 121 0.69 VAL 224 -0.31 ILE 34

ASN 121 0.61 VAL 225 -0.29 ASN 155

ASN 121 0.71 GLU 226 -0.26 THR 168

ASN 121 0.61 TYR 227 -0.32 ASP 229

ASN 121 0.42 VAL 228 -0.27 MET 171

ASN 121 0.36 ASP 229 -0.33 LYS 170

ASN 121 0.43 TRP 230 -0.33 GLY 164

ASN 121 0.36 ILE 231 -0.36 THR 222

ASN 121 0.27 LEU 232 -0.30 ALA 209

ASN 121 0.28 GLU 233 -0.30 GLY 164

ASN 121 0.30 LYS 234 -0.33 ALA 209

ASN 121 0.23 THR 235 -0.36 SER 207

ASN 121 0.18 GLN 236 -0.31 ALA 209

ASN 121 0.19 ALA 237 -0.29 ALA 209

ASN 121 0.16 VAL 238 -0.31 ALA 209

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A ***

CA distance fluctuations for 2602071232343282027

--- normal mode 26 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A *