Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G226A *

CA distance fluctuations for 2602071245243314933

--- normal mode 11 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASN 121 0.29 ILE 1 -0.23 GLU 210

ASN 121 0.33 VAL 2 -0.24 ALA 213

LYS 136 0.30 GLY 3 -0.27 ALA 213

ARG 135 0.21 GLY 4 -0.19 ALA 213

ARG 138 0.14 THR 5 -0.18 ALA 213

PRO 151 0.11 ALA 6 -0.17 GLU 210

THR 154 0.15 SER 7 -0.20 GLU 198

THR 154 0.16 VAL 8 -0.28 GLU 198

THR 154 0.16 ARG 9 -0.38 GLU 198

THR 154 0.19 GLY 10 -0.49 GLU 198

THR 154 0.22 GLU 11 -0.41 GLU 198

THR 154 0.23 TRP 12 -0.37 GLU 198

THR 154 0.22 PRO 13 -0.46 GLU 198

THR 154 0.23 TRP 14 -0.39 GLU 198

THR 154 0.17 GLN 15 -0.32 GLU 198

THR 154 0.12 VAL 16 -0.29 GLU 198

ASN 121 0.14 THR 17 -0.24 GLU 198

ASN 121 0.16 LEU 18 -0.21 GLU 198

ASN 121 0.17 HIS 19 -0.22 GLY 164

ASN 121 0.20 THR 20 -0.23 GLY 164

ASP 70 0.18 THR 21 -0.21 GLY 164

ASN 121 0.21 SER 22 -0.23 GLY 164

ASN 121 0.22 PRO 23 -0.23 GLY 164

GLU 69 0.21 THR 24 -0.23 GLY 164

GLU 69 0.27 GLN 25 -0.22 GLY 164

GLU 69 0.21 ARG 26 -0.24 GLY 164

ASN 121 0.21 HIS 27 -0.25 GLY 164

ASN 121 0.26 LEU 28 -0.27 GLY 164

ASN 121 0.27 CYS 29 -0.24 GLY 164

ASN 121 0.22 GLY 30 -0.18 GLY 164

ASN 121 0.18 GLY 31 -0.19 GLU 198

THR 154 0.18 SER 32 -0.25 GLU 198

THR 154 0.19 ILE 33 -0.33 GLU 198

GLN 236 0.21 ILE 34 -0.38 SER 113

GLN 236 0.32 GLY 35 -0.42 SER 116

VAL 238 0.32 ASN 36 -0.42 GLU 198

VAL 238 0.21 GLN 37 -0.35 SER 116

SER 59 0.13 TRP 38 -0.35 SER 116

THR 154 0.12 ILE 39 -0.25 GLU 198

ASN 121 0.14 LEU 40 -0.21 SER 116

ASN 121 0.25 THR 41 -0.15 ARG 138

ASN 121 0.37 ALA 42 -0.20 ARG 138

ASN 121 0.38 ALA 43 -0.22 ARG 138

ASN 121 0.44 HIS 44 -0.28 ARG 138

ASN 121 0.36 CYS 45 -0.26 GLY 164

ASN 121 0.32 PHE 46 -0.25 GLY 164

ASN 121 0.37 TYR 47 -0.29 GLY 164

ASN 121 0.32 GLY 48 -0.27 GLY 164

ASN 121 0.27 VAL 49 -0.24 GLY 164

ASN 121 0.22 GLU 50 -0.22 ALA 237

ASN 121 0.19 SER 51 -0.17 GLY 164

ASN 121 0.15 PRO 52 -0.18 GLU 198

ASP 70 0.13 LYS 53 -0.20 GLU 198

ASN 121 0.16 ILE 54 -0.19 GLY 164

ASN 121 0.15 LEU 55 -0.21 GLU 198

ASN 121 0.10 ARG 56 -0.26 GLU 198

THR 154 0.08 VAL 57 -0.29 GLU 198

VAL 238 0.10 TYR 58 -0.34 GLU 198

GLN 37 0.16 SER 59 -0.38 GLU 198

VAL 238 0.18 GLY 60 -0.41 GLU 198

VAL 238 0.14 ILE 61 -0.35 GLU 198

VAL 238 0.13 LEU 62 -0.30 GLU 198

THR 102 0.11 GLN 63 -0.24 GLU 198

GLU 69 0.13 GLN 64 -0.22 GLU 198

GLU 69 0.13 SER 65 -0.22 GLY 164

PHE 73 0.12 GLU 66 -0.28 GLU 198

PHE 73 0.10 ILE 67 -0.29 GLU 198

GLU 69 0.11 LYS 68 -0.28 GLU 198

GLN 25 0.27 GLU 69 -0.30 GLU 198

GLN 25 0.18 ASP 70 -0.40 GLU 198

VAL 238 0.08 THR 71 -0.40 GLU 198

VAL 238 0.10 SER 72 -0.43 GLU 198

GLU 66 0.12 PHE 73 -0.35 GLU 198

VAL 238 0.10 PHE 74 -0.33 GLU 198

SER 72 0.09 GLY 75 -0.28 GLU 198

ASP 83 0.07 VAL 76 -0.25 GLU 198

ASP 70 0.07 GLN 77 -0.23 GLU 198

ASP 83 0.09 GLU 78 -0.21 SER 116

ASN 121 0.16 ILE 79 -0.17 SER 116

ASN 121 0.18 ILE 80 -0.21 ALA 237

ASN 121 0.27 ILE 81 -0.19 ALA 237

ASN 121 0.31 HIS 82 -0.19 ARG 138

ASN 121 0.31 ASP 83 -0.19 ARG 138

ASN 121 0.42 GLN 84 -0.22 ARG 138

ASN 121 0.47 TYR 85 -0.24 ARG 138

ASN 121 0.52 LYS 86 -0.30 GLY 164

ASN 121 0.60 MET 87 -0.34 ARG 138

ASN 121 0.65 ALA 88 -0.33 ARG 138

ASN 121 0.82 GLU 89 -0.40 ARG 138

ASN 121 0.79 SER 90 -0.33 ARG 138

ASN 121 0.72 GLY 91 -0.27 ARG 138

ASN 121 0.54 TYR 92 -0.23 ARG 138

ASN 121 0.51 ASP 93 -0.23 ARG 138

ASN 121 0.36 ILE 94 -0.18 ARG 138

ASN 121 0.26 ALA 95 -0.17 ARG 138

ASN 121 0.14 LEU 96 -0.22 SER 116

ASN 121 0.10 LEU 97 -0.23 SER 116

SER 59 0.09 LYS 98 -0.28 SER 116

ILE 61 0.10 LEU 99 -0.29 GLU 198

GLU 66 0.10 GLU 100 -0.29 GLU 198

VAL 238 0.18 THR 101 -0.34 GLU 198

VAL 238 0.26 THR 102 -0.39 GLU 198

VAL 238 0.25 VAL 103 -0.43 GLU 198

VAL 238 0.28 GLN 104 -0.48 GLU 198

VAL 238 0.28 TYR 105 -0.57 GLU 198

GLN 236 0.23 THR 106 -0.59 GLU 198

GLN 236 0.21 ASP 107 -0.63 GLU 198

GLN 236 0.20 SER 108 -0.51 GLU 198

GLN 236 0.22 GLN 109 -0.50 GLU 198

GLN 236 0.26 ARG 110 -0.59 GLU 198

GLN 236 0.25 PRO 111 -0.47 GLU 198

THR 154 0.30 ILE 112 -0.37 GLU 198

THR 154 0.38 SER 113 -0.42 GLY 35

THR 154 0.36 LEU 114 -0.36 PRO 115

THR 154 0.55 PRO 115 -0.36 LEU 114

ASN 155 0.62 SER 116 -0.42 GLY 35

ASN 155 0.65 LYS 117 -0.31 LEU 232

GLU 156 0.94 GLY 118 -0.37 GLY 35

ASN 155 1.06 ASP 119 -0.33 GLY 35

HIS 169 1.10 ARG 120 -0.28 ILE 123

ASN 155 1.61 ASN 121 -0.18 GLY 118

ASN 155 1.57 VAL 122 -0.24 TYR 105

THR 154 1.78 ILE 123 -0.28 ARG 120

THR 154 1.16 TYR 124 -0.26 ARG 120

THR 154 0.75 THR 125 -0.22 ARG 120

THR 154 0.57 ASP 126 -0.17 ARG 120

VAL 153 0.46 CYS 127 -0.14 GLU 226

THR 154 0.26 TRP 128 -0.11 GLU 226

ASN 121 0.25 VAL 129 -0.10 TRP 208

ASN 121 0.19 THR 130 -0.16 TRP 208

ASN 121 0.21 GLY 131 -0.21 TRP 208

ASN 121 0.20 TRP 132 -0.24 GLY 164

ASN 121 0.25 GLY 133 -0.30 TRP 208

ASN 121 0.29 TYR 134 -0.37 GLU 210

ASN 121 0.30 ARG 135 -0.37 GLU 210

ASN 121 0.35 LYS 136 -0.47 GLU 210

ASN 121 0.38 LEU 137 -0.55 GLU 210

GLY 180 0.34 ARG 138 -0.51 GLY 164

ASN 121 0.27 ASP 139 -0.42 GLY 164

ASN 121 0.24 LYS 140 -0.38 GLY 164

ASN 121 0.22 ILE 141 -0.32 GLY 164

ASN 121 0.19 GLN 142 -0.27 GLY 164

GLU 69 0.15 ASN 143 -0.24 GLY 164

ASN 121 0.11 THR 144 -0.20 GLY 164

ASN 121 0.12 LEU 145 -0.19 GLU 198

ASN 121 0.16 GLN 146 -0.18 GLU 210

GLN 146 0.14 LYS 147 -0.14 TRP 208

ASN 121 0.19 ALA 148 -0.12 LYS 181

GLY 4 0.20 LYS 149 -0.13 GLU 226

ASN 121 0.27 ILE 150 -0.16 GLU 226

ASN 197 0.36 PRO 151 -0.20 GLU 226

VAL 153 0.77 LEU 152 -0.25 GLU 226

ILE 123 1.21 VAL 153 -0.23 HIS 169

ILE 123 1.78 THR 154 -0.25 HIS 169

ASN 121 1.61 ASN 155 -0.17 ARG 177

VAL 122 1.53 GLU 156 -0.21 SER 90

ILE 123 1.34 GLU 157 -0.17 LEU 137

ASN 121 1.33 CYS 158 -0.21 LEU 137

ASN 121 1.51 GLN 159 -0.27 ARG 138

ASN 121 1.28 LYS 160 -0.29 LEU 137

ASN 121 1.12 ARG 161 -0.31 LEU 137

ASN 121 1.16 TYR 162 -0.38 LEU 137

ASN 121 1.20 ARG 163 -0.43 ARG 138

ASN 121 1.04 GLY 164 -0.51 ARG 138

ASN 121 1.11 HIS 165 -0.40 ARG 138

ASN 121 1.23 LYS 166 -0.33 ARG 138

ASN 121 1.37 ILE 167 -0.25 ARG 138

ASN 121 1.25 THR 168 -0.21 ARG 138

ARG 120 1.10 HIS 169 -0.25 THR 154

ASN 121 0.81 LYS 170 -0.19 LEU 152

ASN 121 0.97 MET 171 -0.17 LYS 185

ASN 121 0.94 ILE 172 -0.18 HIS 169

ASN 121 0.90 CYS 173 -0.20 HIS 169

ASN 121 0.63 ALA 174 -0.20 GLY 175

ASN 121 0.53 GLY 175 -0.20 ALA 174

ILE 123 0.48 TYR 176 -0.16 HIS 169

ILE 123 0.61 ARG 177 -0.17 ASN 155

ASN 121 0.47 GLU 178 -0.12 ASN 155

ASN 121 0.47 GLY 179 -0.14 ARG 215

ASN 121 0.36 GLY 180 -0.20 GLY 3

ASN 121 0.34 LYS 181 -0.12 ALA 148

ASN 121 0.42 ASP 182 -0.12 ARG 217

ASN 121 0.40 ALA 183 -0.19 TRP 208

ASN 121 0.37 CYS 184 -0.36 TRP 208

ASN 121 0.33 LYS 185 -0.51 TRP 208

ASN 121 0.28 GLY 186 -0.35 TRP 208

ASN 121 0.31 ASP 187 -0.28 TRP 208

ASN 121 0.37 SER 188 -0.26 TRP 208

ASN 121 0.32 GLY 189 -0.17 GLY 164

ASN 121 0.25 GLY 190 -0.16 SER 207

ASN 121 0.21 PRO 191 -0.13 SER 207

ASN 121 0.26 LEU 192 -0.09 GLU 226

THR 154 0.38 SER 193 -0.12 SER 72

THR 154 0.58 CYS 194 -0.13 SER 72

THR 154 0.68 LYS 195 -0.23 ARG 110

THR 154 0.89 HIS 196 -0.30 ARG 110

THR 154 0.87 ASN 197 -0.47 ASP 107

THR 154 0.70 GLU 198 -0.63 ASP 107

THR 154 0.61 VAL 199 -0.50 ARG 110

THR 154 0.51 TRP 200 -0.33 ILE 112

THR 154 0.53 HIS 201 -0.28 ILE 112

THR 154 0.38 LEU 202 -0.14 SER 72

THR 154 0.42 VAL 203 -0.13 GLU 226

ASN 121 0.37 GLY 204 -0.13 ILE 150

ASN 121 0.38 ILE 205 -0.11 LYS 185

ASN 121 0.44 THR 206 -0.22 SER 207

ASN 121 0.56 SER 207 -0.29 LYS 185

ASN 121 0.67 TRP 208 -0.51 LYS 185

ASN 121 0.72 GLY 209 -0.41 LYS 185

ASN 121 0.73 GLU 210 -0.55 LEU 137

ASN 121 0.57 GLY 211 -0.54 GLU 210

ASN 121 0.50 CYS 212 -0.31 ARG 135

ASN 121 0.50 ALA 213 -0.27 GLY 3

ASN 121 0.59 GLN 214 -0.24 ARG 135

ASN 121 0.61 ARG 215 -0.22 GLY 3

ASN 121 0.78 GLU 216 -0.18 LEU 137

ASN 121 0.80 ARG 217 -0.26 CYS 212

ASN 121 0.77 PRO 218 -0.13 LYS 185

ASN 121 0.70 ALA 219 -0.19 CYS 184

ASN 121 0.82 VAL 220 -0.23 LYS 185

ASN 121 0.65 TYR 221 -0.15 LYS 185

ASN 121 0.60 THR 222 -0.14 LYS 185

ASN 121 0.57 ASN 223 -0.22 LEU 152

ASN 121 0.29 VAL 224 -0.15 LEU 152

ASN 155 0.37 VAL 225 -0.17 THR 125

TYR 227 0.30 GLU 226 -0.25 LEU 152

GLU 226 0.30 TYR 227 -0.13 LEU 152

ASN 155 0.19 VAL 228 -0.17 SER 116

PRO 111 0.18 ASP 229 -0.17 LYS 117

PRO 111 0.15 TRP 230 -0.14 ARG 138

PRO 111 0.18 ILE 231 -0.27 SER 116

PRO 111 0.22 LEU 232 -0.35 SER 116

GLY 35 0.19 GLU 233 -0.24 SER 116

GLY 35 0.20 LYS 234 -0.25 SER 116

GLY 35 0.28 THR 235 -0.34 SER 116

GLY 35 0.32 GLN 236 -0.32 GLY 118

ASN 36 0.27 ALA 237 -0.22 GLU 50

ASN 36 0.32 VAL 238 -0.25 GLY 118

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G226A ***

CA distance fluctuations for 2602071245243314933

--- normal mode 11 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G226A *