Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *

CA distance fluctuations for 2602071309593453456

--- normal mode 17 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
GLU 69 0.21 ILE 1 -0.46 PRO 23

GLU 69 0.23 VAL 2 -0.48 PRO 23

GLU 198 0.23 GLY 3 -0.40 PRO 23

GLU 198 0.21 GLY 4 -0.33 PRO 23

GLU 69 0.19 THR 5 -0.22 PRO 23

GLU 69 0.19 ALA 6 -0.19 SER 72

SER 113 0.15 SER 7 -0.28 ASP 70

SER 113 0.16 VAL 8 -0.37 ASP 70

SER 113 0.17 ARG 9 -0.49 ASP 70

SER 113 0.20 GLY 10 -0.55 ASP 70

SER 113 0.22 GLU 11 -0.44 ASP 70

SER 113 0.21 TRP 12 -0.43 ASP 70

LEU 232 0.19 PRO 13 -0.52 ASP 70

LEU 232 0.21 TRP 14 -0.48 SER 72

SER 32 0.18 GLN 15 -0.39 SER 72

LEU 232 0.13 VAL 16 -0.41 SER 72

GLU 69 0.14 THR 17 -0.25 SER 72

GLU 69 0.14 LEU 18 -0.24 GLU 198

GLU 69 0.33 HIS 19 -0.26 GLY 190

ASP 70 0.48 THR 20 -0.54 CYS 45

ASP 70 0.86 THR 21 -0.75 VAL 49

ASP 70 0.95 SER 22 -1.10 GLY 48

ASP 70 1.30 PRO 23 -1.03 TYR 47

ASP 70 1.71 THR 24 -0.79 GLY 48

ASP 70 1.09 GLN 25 -0.62 GLU 50

GLU 69 0.97 ARG 26 -0.64 GLY 186

GLU 69 0.57 HIS 27 -0.42 GLY 186

GLU 69 0.43 LEU 28 -0.58 CYS 29

GLU 69 0.25 CYS 29 -0.58 LEU 28

TRP 132 0.18 GLY 30 -0.48 GLY 190

GLY 131 0.13 GLY 31 -0.33 SER 22

GLN 15 0.18 SER 32 -0.34 SER 72

LEU 232 0.21 ILE 33 -0.41 GLU 198

LEU 232 0.29 ILE 34 -0.45 GLU 198

LEU 232 0.33 GLY 35 -0.55 GLU 198

LEU 232 0.26 ASN 36 -0.55 GLU 198

THR 24 0.20 GLN 37 -0.45 GLU 198

GLU 50 0.23 TRP 38 -0.40 GLU 198

GLU 50 0.19 ILE 39 -0.32 GLU 198

GLU 50 0.24 LEU 40 -0.31 PRO 23

GLU 50 0.25 THR 41 -0.44 PRO 23

GLU 50 0.30 ALA 42 -0.63 PRO 23

GLU 50 0.43 ALA 43 -0.71 PRO 23

GLU 50 0.33 HIS 44 -0.93 PRO 23

GLY 186 0.21 CYS 45 -0.83 SER 22

GLU 50 0.30 PHE 46 -0.86 SER 22

GLU 50 0.20 TYR 47 -1.06 SER 22

VAL 49 0.20 GLY 48 -1.10 SER 22

GLY 48 0.20 VAL 49 -0.94 SER 22

ILE 80 0.61 GLU 50 -0.76 SER 22

LEU 28 0.16 SER 51 -0.23 SER 22

LYS 53 0.16 PRO 52 -0.22 GLU 198

GLN 77 0.21 LYS 53 -0.39 LYS 68

ASP 70 0.19 ILE 54 -0.51 GLU 50

ASP 70 0.15 LEU 55 -0.38 VAL 49

THR 24 0.28 ARG 56 -0.28 ILE 54

THR 24 0.23 VAL 57 -0.30 GLU 198

THR 24 0.29 TYR 58 -0.40 SER 72

THR 24 0.25 SER 59 -0.62 SER 72

THR 24 0.24 GLY 60 -0.65 ASP 70

THR 24 0.21 ILE 61 -0.47 ASP 70

LEU 232 0.16 LEU 62 -0.37 ASP 70

GLU 69 0.23 GLN 63 -0.23 ASP 70

GLU 69 0.41 GLN 64 -0.16 GLU 50

GLU 69 0.46 SER 65 -0.24 GLU 50

THR 24 0.36 GLU 66 -0.26 ASP 70

THR 24 0.45 ILE 67 -0.30 GLU 50

THR 24 0.72 LYS 68 -0.39 LYS 53

THR 24 1.08 GLU 69 -0.49 THR 101

THR 24 1.71 ASP 70 -0.69 THR 106

THR 24 1.01 THR 71 -0.51 GLY 60

THR 24 0.92 SER 72 -0.62 GLY 60

THR 24 0.55 PHE 73 -0.45 GLU 69

THR 24 0.41 PHE 74 -0.43 GLU 69

THR 21 0.40 GLY 75 -0.43 GLU 69

THR 21 0.21 VAL 76 -0.30 GLU 198

LYS 53 0.21 GLN 77 -0.30 GLU 69

GLU 50 0.42 GLU 78 -0.25 GLU 198

GLU 50 0.53 ILE 79 -0.30 SER 22

GLU 50 0.61 ILE 80 -0.34 PRO 23

GLU 50 0.60 ILE 81 -0.54 PRO 23

GLU 50 0.51 HIS 82 -0.56 PRO 23

GLU 50 0.51 ASP 83 -0.59 PRO 23

GLU 50 0.43 GLN 84 -0.67 PRO 23

GLU 50 0.47 TYR 85 -0.76 PRO 23

GLU 50 0.44 LYS 86 -0.91 PRO 23

GLU 50 0.37 MET 87 -0.98 PRO 23

GLU 50 0.30 ALA 88 -0.91 PRO 23

GLU 50 0.28 GLU 89 -0.86 PRO 23

GLU 50 0.33 SER 90 -0.80 PRO 23

GLU 50 0.32 GLY 91 -0.74 PRO 23

GLU 50 0.37 TYR 92 -0.68 PRO 23

GLU 50 0.36 ASP 93 -0.72 PRO 23

GLU 50 0.36 ILE 94 -0.58 PRO 23

GLU 50 0.43 ALA 95 -0.47 PRO 23

GLU 50 0.38 LEU 96 -0.30 PRO 23

GLU 50 0.32 LEU 97 -0.27 GLU 198

GLU 50 0.29 LYS 98 -0.33 GLU 198

THR 24 0.23 LEU 99 -0.37 GLU 198

THR 24 0.33 GLU 100 -0.43 GLU 69

THR 24 0.37 THR 101 -0.49 GLU 69

THR 24 0.32 THR 102 -0.48 GLU 198

THR 24 0.30 VAL 103 -0.55 ASP 70

THR 24 0.31 GLN 104 -0.67 ASP 70

LEU 232 0.25 TYR 105 -0.63 ASP 70

THR 24 0.24 THR 106 -0.69 ASP 70

LEU 232 0.22 ASP 107 -0.64 ASP 70

LEU 232 0.20 SER 108 -0.68 ASP 70

LEU 232 0.22 GLN 109 -0.63 ASP 70

LEU 232 0.27 ARG 110 -0.62 GLU 198

LEU 232 0.29 PRO 111 -0.60 GLU 198

ASP 229 0.21 ILE 112 -0.50 GLU 198

GLU 11 0.22 SER 113 -0.37 GLU 198

ILE 112 0.20 LEU 114 -0.28 PRO 23

GLU 50 0.17 PRO 115 -0.31 PRO 23

GLU 50 0.18 SER 116 -0.28 PRO 23

GLU 50 0.21 LYS 117 -0.37 ASN 155

GLU 50 0.18 GLY 118 -0.41 GLU 156

GLU 50 0.16 ASP 119 -0.39 THR 154

VAL 122 0.19 ARG 120 -0.54 THR 154

ASN 197 0.24 ASN 121 -0.76 THR 154

ASN 197 0.27 VAL 122 -0.34 PRO 23

HIS 169 0.50 ILE 123 -0.31 PRO 23

HIS 169 0.36 TYR 124 -0.33 PRO 23

ASN 197 0.43 THR 125 -0.32 PRO 23

GLU 198 0.44 ASP 126 -0.32 SER 72

GLU 198 0.29 CYS 127 -0.34 PRO 23

GLU 198 0.21 TRP 128 -0.34 PRO 23

SER 207 0.13 VAL 129 -0.40 PRO 23

ILE 94 0.11 THR 130 -0.34 PRO 23

GLY 190 0.19 GLY 131 -0.33 PRO 23

GLU 69 0.30 TRP 132 -0.35 ARG 26

GLU 69 0.30 GLY 133 -0.51 ARG 26

GLU 69 0.34 TYR 134 -0.51 PRO 23

GLU 69 0.32 ARG 135 -0.45 PRO 23

GLU 69 0.32 LYS 136 -0.55 PRO 23

GLU 69 0.29 LEU 137 -0.73 PRO 23

GLU 69 0.37 ARG 138 -0.66 THR 24

GLU 69 0.43 ASP 139 -0.54 THR 24

GLU 69 0.49 LYS 140 -0.47 THR 24

GLU 69 0.49 ILE 141 -0.43 ARG 26

GLU 69 0.46 GLN 142 -0.24 ARG 26

GLU 69 0.46 ASN 143 -0.13 LYS 140

GLU 69 0.29 THR 144 -0.17 SER 72

GLU 69 0.19 LEU 145 -0.24 SER 72

GLU 69 0.19 GLN 146 -0.24 PRO 23

GLU 198 0.14 LYS 147 -0.29 PRO 23

GLU 198 0.24 ALA 148 -0.35 PRO 23

GLU 198 0.38 LYS 149 -0.36 PRO 23

GLU 198 0.33 ILE 150 -0.42 PRO 23

GLU 198 0.38 PRO 151 -0.43 PRO 23

THR 125 0.29 LEU 152 -0.51 ASN 121

ARG 177 0.29 VAL 153 -0.56 ASN 121

ARG 177 0.19 THR 154 -0.76 ASN 121

ILE 123 0.22 ASN 155 -0.60 ASN 121

GLU 50 0.19 GLU 156 -0.61 ASN 121

GLU 50 0.14 GLU 157 -0.55 PRO 23

GLU 50 0.15 CYS 158 -0.60 PRO 23

GLU 50 0.19 GLN 159 -0.59 PRO 23

GLU 50 0.16 LYS 160 -0.57 PRO 23

ASN 197 0.17 ARG 161 -0.63 PRO 23

GLU 50 0.17 TYR 162 -0.67 PRO 23

GLU 50 0.21 ARG 163 -0.61 PRO 23

GLU 50 0.26 GLY 164 -0.64 PRO 23

GLU 50 0.26 HIS 165 -0.69 PRO 23

GLU 50 0.28 LYS 166 -0.64 PRO 23

GLU 50 0.25 ILE 167 -0.64 PRO 23

ILE 123 0.32 THR 168 -0.60 PRO 23

ILE 123 0.50 HIS 169 -0.55 PRO 23

ILE 123 0.42 LYS 170 -0.58 PRO 23

ILE 123 0.33 MET 171 -0.61 PRO 23

ILE 123 0.37 ILE 172 -0.56 PRO 23

THR 125 0.23 CYS 173 -0.58 PRO 23

THR 125 0.26 ALA 174 -0.54 PRO 23

GLU 198 0.30 GLY 175 -0.54 PRO 23

GLU 198 0.37 TYR 176 -0.52 PRO 23

GLU 198 0.40 ARG 177 -0.55 PRO 23

GLU 198 0.38 GLU 178 -0.58 PRO 23

GLU 198 0.32 GLY 179 -0.60 PRO 23

GLU 198 0.30 GLY 180 -0.55 PRO 23

GLU 198 0.28 LYS 181 -0.50 PRO 23

GLU 198 0.21 ASP 182 -0.57 PRO 23

GLU 69 0.16 ALA 183 -0.60 PRO 23

GLU 69 0.22 CYS 184 -0.69 PRO 23

GLU 69 0.27 LYS 185 -0.79 PRO 23

GLU 69 0.29 GLY 186 -0.64 ARG 26

GLY 133 0.22 ASP 187 -0.55 PRO 23

GLY 189 0.18 SER 188 -0.65 PRO 23

GLU 50 0.18 GLY 189 -0.54 PRO 23

GLY 131 0.19 GLY 190 -0.48 GLY 30

ILE 205 0.14 PRO 191 -0.39 PRO 23

TYR 92 0.14 LEU 192 -0.41 PRO 23

TYR 227 0.14 SER 193 -0.33 PRO 23

LYS 195 0.26 CYS 194 -0.31 PRO 23

ARG 177 0.27 LYS 195 -0.36 ASP 70

ARG 177 0.29 HIS 196 -0.35 ASP 70

THR 125 0.43 ASN 197 -0.44 ASP 70

ASP 126 0.44 GLU 198 -0.62 ARG 110

ARG 177 0.20 VAL 199 -0.49 PRO 111

ARG 177 0.13 TRP 200 -0.46 ILE 112

GLU 11 0.13 HIS 201 -0.31 ASP 70

GLU 50 0.14 LEU 202 -0.34 PRO 23

VAL 224 0.18 VAL 203 -0.39 PRO 23

GLU 50 0.19 GLY 204 -0.47 PRO 23

GLU 50 0.20 ILE 205 -0.53 PRO 23

GLU 50 0.16 THR 206 -0.61 PRO 23

GLU 50 0.18 SER 207 -0.76 PRO 23

LYS 185 0.18 TRP 208 -0.84 PRO 23

THR 125 0.16 ALA 209 -0.84 PRO 23

GLY 211 0.21 GLU 210 -0.87 PRO 23

GLU 210 0.21 GLY 211 -0.90 PRO 23

GLU 69 0.18 CYS 212 -0.77 PRO 23

GLU 198 0.24 ALA 213 -0.67 PRO 23

GLU 198 0.24 GLN 214 -0.72 PRO 23

GLU 198 0.29 ARG 215 -0.68 PRO 23

GLU 198 0.27 GLU 216 -0.65 PRO 23

GLU 198 0.21 ARG 217 -0.70 PRO 23

THR 125 0.24 PRO 218 -0.66 PRO 23

THR 125 0.20 ALA 219 -0.68 PRO 23

ILE 123 0.21 VAL 220 -0.69 PRO 23

ILE 123 0.21 TYR 221 -0.63 PRO 23

GLU 50 0.24 THR 222 -0.61 PRO 23

ILE 123 0.35 ASN 223 -0.53 PRO 23

ILE 123 0.23 VAL 224 -0.45 PRO 23

ILE 123 0.26 VAL 225 -0.42 PRO 23

ILE 123 0.32 GLU 226 -0.46 PRO 23

GLU 50 0.30 TYR 227 -0.43 PRO 23

GLU 50 0.28 VAL 228 -0.33 PRO 23

GLU 50 0.30 ASP 229 -0.32 PRO 23

GLU 50 0.35 TRP 230 -0.36 PRO 23

GLU 50 0.32 ILE 231 -0.30 PRO 23

GLY 35 0.33 LEU 232 -0.21 PRO 23

GLU 50 0.33 GLU 233 -0.24 PRO 23

GLU 50 0.38 LYS 234 -0.22 PRO 23

GLU 50 0.34 THR 235 -0.32 GLU 198

GLU 50 0.30 GLN 236 -0.30 GLU 198

GLU 50 0.34 ALA 237 -0.26 GLU 198

GLU 50 0.35 VAL 238 -0.35 GLU 198

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A-G226A ***

CA distance fluctuations for 2602071309593453456

--- normal mode 17 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *