Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *

CA distance fluctuations for 2602071309593453456

--- normal mode 26 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASN 121 0.33 ILE 1 -0.32 GLN 109

ASN 121 0.29 VAL 2 -0.31 ARG 215

ASN 121 0.24 GLY 3 -0.28 GLY 180

ASN 197 0.28 GLY 4 -0.31 ASP 107

ASN 197 0.34 THR 5 -0.28 ASP 107

ASN 197 0.38 ALA 6 -0.29 GLN 104

GLU 198 0.46 SER 7 -0.31 SER 108

GLU 198 0.48 VAL 8 -0.32 SER 108

GLU 198 0.46 ARG 9 -0.32 GLN 104

GLU 198 0.47 GLY 10 -0.42 SER 108

GLU 198 0.60 GLU 11 -0.52 ASP 107

GLU 198 0.50 TRP 12 -0.50 PRO 13

GLU 198 0.37 PRO 13 -0.50 TRP 12

THR 17 0.38 TRP 14 -0.40 ALA 209

GLU 198 0.45 GLN 15 -0.40 ALA 209

THR 17 0.56 VAL 16 -0.39 ALA 209

VAL 16 0.56 THR 17 -0.37 GLY 186

GLY 31 0.44 LEU 18 -0.34 GLU 210

ASN 121 0.43 HIS 19 -0.26 GLU 210

ASN 121 0.44 THR 20 -0.19 GLU 210

ASN 121 0.41 THR 21 -0.16 ASP 70

ASN 121 0.46 SER 22 -0.13 ASP 70

ASN 121 0.46 PRO 23 -0.09 SER 22

LYS 68 0.59 THR 24 -0.07 ARG 215

LYS 68 0.58 GLN 25 -0.14 ARG 215

LYS 68 0.64 ARG 26 -0.20 GLU 210

ASN 121 0.42 HIS 27 -0.28 GLY 211

ASN 121 0.47 LEU 28 -0.29 GLU 210

ASN 121 0.48 CYS 29 -0.38 GLU 210

PRO 191 0.57 GLY 30 -0.41 ALA 209

LEU 18 0.44 GLY 31 -0.48 SER 207

LEU 18 0.37 SER 32 -0.46 SER 207

VAL 57 0.35 ILE 33 -0.45 SER 207

SER 113 0.29 ILE 34 -0.44 ILE 205

SER 116 0.21 GLY 35 -0.40 SER 207

SER 116 0.15 ASN 36 -0.37 SER 207

ASN 121 0.23 GLN 37 -0.36 SER 207

ASN 121 0.30 TRP 38 -0.43 SER 207

ASN 121 0.37 ILE 39 -0.44 SER 207

ASN 121 0.45 LEU 40 -0.53 SER 207

ASN 121 0.58 THR 41 -0.51 SER 207

ASN 121 0.64 ALA 42 -0.47 SER 207

ASN 121 0.64 ALA 43 -0.29 GLU 210

TYR 47 0.66 HIS 44 -0.30 GLU 210

ASN 121 0.59 CYS 45 -0.28 GLU 210

VAL 49 0.57 PHE 46 -0.22 PHE 74

HIS 44 0.66 TYR 47 -0.24 LEU 55

ASN 121 0.52 GLY 48 -0.29 GLU 78

PHE 46 0.57 VAL 49 -0.28 GLU 78

ASN 121 0.50 GLU 50 -0.34 GLN 77

PHE 46 0.53 SER 51 -0.43 ASP 70

ASN 121 0.46 PRO 52 -0.44 ASP 70

ASN 121 0.42 LYS 53 -0.66 ASP 70

ASN 121 0.43 ILE 54 -0.41 ASP 70

ASN 121 0.42 LEU 55 -0.28 ASP 70

ASN 121 0.37 ARG 56 -0.28 ASP 70

ILE 33 0.35 VAL 57 -0.36 GLU 210

SER 59 0.43 TYR 58 -0.33 ALA 209

TYR 58 0.43 SER 59 -0.37 ALA 209

GLU 198 0.33 GLY 60 -0.41 VAL 103

GLU 198 0.41 ILE 61 -0.38 VAL 103

GLU 198 0.43 LEU 62 -0.33 GLN 104

GLU 198 0.39 GLN 63 -0.29 VAL 103

GLU 198 0.37 GLN 64 -0.32 PHE 73

GLU 198 0.32 SER 65 -0.34 PHE 73

ASP 70 0.47 GLU 66 -0.36 THR 101

ARG 26 0.58 ILE 67 -0.50 PHE 73

ARG 26 0.64 LYS 68 -0.39 THR 71

ARG 26 0.28 GLU 69 -0.24 LYS 53

GLU 66 0.47 ASP 70 -0.66 LYS 53

ARG 26 0.32 THR 71 -0.46 THR 101

SER 108 0.29 SER 72 -0.65 THR 101

GLN 109 0.33 PHE 73 -0.50 ILE 67

ASN 121 0.23 PHE 74 -0.45 SER 72

ASN 121 0.29 GLY 75 -0.59 SER 72

ASN 121 0.35 VAL 76 -0.40 SER 72

ASN 121 0.33 GLN 77 -0.46 ASP 70

ASN 121 0.39 GLU 78 -0.35 ASP 70

ASN 121 0.47 ILE 79 -0.26 ASP 70

ASN 121 0.49 ILE 80 -0.26 GLU 210

ASN 121 0.55 ILE 81 -0.25 GLY 164

ASN 121 0.59 HIS 82 -0.27 GLY 164

ASN 121 0.56 ASP 83 -0.22 GLY 164

ASN 121 0.61 GLN 84 -0.26 GLY 164

ASN 121 0.62 TYR 85 -0.29 GLY 164

ASN 121 0.57 LYS 86 -0.27 GLY 164

ASN 121 0.56 MET 87 -0.31 GLY 164

ASN 121 0.60 ALA 88 -0.32 GLY 164

ASN 121 0.54 GLU 89 -0.33 GLY 164

ASN 121 0.59 SER 90 -0.38 GLY 164

ASN 121 0.71 GLY 91 -0.38 GLY 164

ASN 121 0.73 TYR 92 -0.30 GLY 164

ASN 121 0.70 ASP 93 -0.34 ALA 209

ASN 121 0.66 ILE 94 -0.33 SER 207

ASN 121 0.58 ALA 95 -0.38 SER 207

ASN 121 0.49 LEU 96 -0.36 SER 207

ASN 121 0.42 LEU 97 -0.36 ALA 209

ASN 121 0.35 LYS 98 -0.36 SER 72

ASN 121 0.29 LEU 99 -0.44 SER 72

ASN 121 0.25 GLU 100 -0.59 SER 72

ASN 121 0.19 THR 101 -0.65 SER 72

ASN 121 0.14 THR 102 -0.46 SER 72

ASN 121 0.13 VAL 103 -0.41 GLY 60

PHE 73 0.11 GLN 104 -0.40 GLY 60

PHE 73 0.24 TYR 105 -0.33 ALA 209

PHE 73 0.29 THR 106 -0.40 GLU 11

ASP 70 0.26 ASP 107 -0.52 GLU 11

ASP 70 0.30 SER 108 -0.43 GLU 11

TYR 58 0.38 GLN 109 -0.41 TRP 12

TYR 58 0.31 ARG 110 -0.35 ALA 209

VAL 57 0.30 PRO 111 -0.35 ALA 209

HIS 19 0.35 ILE 112 -0.35 CYS 173

HIS 19 0.36 SER 113 -0.27 CYS 173

THR 41 0.39 LEU 114 -0.29 CYS 173

THR 41 0.43 PRO 115 -0.31 THR 154

THR 41 0.35 SER 116 -0.29 THR 154

ASP 229 0.37 LYS 117 -0.31 THR 154

SER 51 0.32 GLY 118 -0.20 ASN 197

THR 41 0.38 ASP 119 -0.28 ASN 197

TYR 227 0.54 ARG 120 -0.32 THR 154

HIS 169 0.98 ASN 121 -0.36 ASN 197

ASN 223 0.57 VAL 122 -0.39 ASN 197

HIS 169 0.60 ILE 123 -0.29 GLU 198

TYR 47 0.40 TYR 124 -0.15 GLU 198

TYR 47 0.36 THR 125 -0.17 ASP 107

TYR 47 0.34 ASP 126 -0.22 ASP 107

TYR 47 0.37 CYS 127 -0.28 ASP 107

GLY 131 0.41 TRP 128 -0.32 ASP 107

TRP 128 0.38 VAL 129 -0.37 TRP 14

GLY 131 0.61 THR 130 -0.38 PRO 13

THR 130 0.61 GLY 131 -0.34 ALA 213

ASN 121 0.35 TRP 132 -0.29 CYS 212

ASN 121 0.37 GLY 133 -0.32 THR 17

ASN 121 0.33 TYR 134 -0.32 ARG 215

ASN 121 0.29 ARG 135 -0.30 ARG 215

GLY 48 0.27 LYS 136 -0.39 ARG 215

GLY 48 0.27 LEU 137 -0.41 ARG 215

GLY 48 0.28 ARG 138 -0.35 ARG 215

PRO 23 0.28 ASP 139 -0.30 ARG 215

LYS 68 0.33 LYS 140 -0.26 ARG 215

ASN 121 0.34 ILE 141 -0.24 ARG 215

GLU 198 0.32 GLN 142 -0.24 TYR 58

GLU 198 0.34 ASN 143 -0.28 TYR 58

GLU 198 0.38 THR 144 -0.28 GLN 104

GLU 198 0.38 LEU 145 -0.33 VAL 103

LYS 147 0.41 GLN 146 -0.30 GLN 109

GLN 146 0.41 LYS 147 -0.35 ASP 107

ASN 197 0.29 ALA 148 -0.33 ASP 107

TYR 47 0.30 LYS 149 -0.32 ASP 107

TYR 47 0.32 ILE 150 -0.29 ASP 107

TYR 47 0.32 PRO 151 -0.24 ASP 107

TYR 47 0.37 LEU 152 -0.23 ILE 112

TYR 47 0.27 VAL 153 -0.32 VAL 203

ASN 121 0.28 THR 154 -0.32 ARG 120

ASN 121 0.42 ASN 155 -0.33 VAL 225

ASN 121 0.27 GLU 156 -0.26 LYS 117

ASN 121 0.20 GLU 157 -0.27 LEU 202

ASN 121 0.30 CYS 158 -0.31 ILE 34

ASN 121 0.30 GLN 159 -0.29 ILE 34

ASN 121 0.21 LYS 160 -0.28 ILE 33

ASN 121 0.23 ARG 161 -0.31 ILE 33

ASN 121 0.28 TYR 162 -0.32 ILE 33

ASN 121 0.27 ARG 163 -0.28 ILE 33

ASN 121 0.26 GLY 164 -0.40 HIS 165

ASN 121 0.36 HIS 165 -0.40 GLY 164

ASN 121 0.42 LYS 166 -0.30 GLY 91

ASN 121 0.51 ILE 167 -0.28 ILE 34

ASN 121 0.66 THR 168 -0.32 HIS 169

ASN 121 0.98 HIS 169 -0.32 THR 168

ASN 121 0.97 LYS 170 -0.30 ASP 229

ASN 121 0.78 MET 171 -0.40 ASN 223

ASN 121 0.75 ILE 172 -0.32 ASN 223

ASN 121 0.47 CYS 173 -0.38 GLY 204

ASN 121 0.36 ALA 174 -0.34 SER 193

TYR 47 0.27 GLY 175 -0.32 TRP 14

GLY 48 0.22 TYR 176 -0.27 ASP 107

VAL 153 0.26 ARG 177 -0.24 GLN 109

ASN 121 0.20 GLU 178 -0.29 LYS 136

ASN 121 0.20 GLY 179 -0.31 TRP 14

ASN 121 0.21 GLY 180 -0.31 GLN 109

GLY 48 0.25 LYS 181 -0.32 GLN 109

ASN 121 0.31 ASP 182 -0.39 TRP 14

ASN 121 0.39 ALA 183 -0.38 TRP 14

GLY 48 0.36 CYS 184 -0.43 CYS 212

GLY 48 0.41 LYS 185 -0.50 GLY 211

PRO 23 0.40 GLY 186 -0.37 THR 17

ASN 121 0.43 ASP 187 -0.37 GLY 211

ASN 121 0.50 SER 188 -0.49 ALA 209

CYS 45 0.58 GLY 189 -0.51 SER 207

GLY 30 0.53 GLY 190 -0.47 ALA 209

GLY 30 0.57 PRO 191 -0.40 ALA 219

ASN 121 0.45 LEU 192 -0.37 PRO 218

GLY 30 0.54 SER 193 -0.34 ALA 174

GLY 30 0.41 CYS 194 -0.24 VAL 153

GLY 30 0.44 LYS 195 -0.15 VAL 199

GLY 30 0.37 HIS 196 -0.28 GLU 198

GLU 11 0.46 ASN 197 -0.39 VAL 122

GLU 11 0.60 GLU 198 -0.29 VAL 122

THR 17 0.35 VAL 199 -0.17 VAL 153

GLN 15 0.40 TRP 200 -0.21 VAL 153

GLY 30 0.40 HIS 201 -0.29 CYS 173

THR 41 0.50 LEU 202 -0.37 CYS 173

ASN 121 0.55 VAL 203 -0.37 CYS 173

ASN 121 0.60 GLY 204 -0.38 CYS 173

ASN 121 0.62 ILE 205 -0.44 ILE 33

ASN 121 0.55 THR 206 -0.48 ALA 209

ASN 121 0.55 SER 207 -0.53 LEU 40

ASN 121 0.46 TRP 208 -0.54 ALA 209

ASN 121 0.36 ALA 209 -0.54 TRP 208

ASN 121 0.30 GLU 210 -0.44 SER 188

ASN 121 0.27 GLY 211 -0.50 LYS 185

ASN 121 0.28 CYS 212 -0.43 CYS 184

ASN 121 0.26 ALA 213 -0.37 TRP 14

ASN 121 0.22 GLN 214 -0.54 ARG 215

ASN 121 0.19 ARG 215 -0.54 GLN 214

ASN 121 0.21 GLU 216 -0.32 ILE 33

ASN 121 0.25 ARG 217 -0.36 ILE 33

ASN 121 0.30 PRO 218 -0.38 PRO 191

ASN 121 0.38 ALA 219 -0.40 PRO 191

ASN 121 0.51 VAL 220 -0.44 TYR 221

ASN 121 0.64 TYR 221 -0.44 VAL 220

ASN 121 0.76 THR 222 -0.39 ILE 34

ASN 121 0.90 ASN 223 -0.40 MET 171

ASN 121 0.76 VAL 224 -0.28 ILE 34

ASN 121 0.69 VAL 225 -0.33 ASN 155

ASN 121 0.80 GLU 226 -0.30 ASN 155

ASN 121 0.69 TYR 227 -0.30 ASP 229

ASN 121 0.49 VAL 228 -0.26 MET 171

ASN 121 0.43 ASP 229 -0.30 LYS 170

ASN 121 0.48 TRP 230 -0.28 LYS 166

ASN 121 0.43 ILE 231 -0.32 THR 222

ASN 121 0.34 LEU 232 -0.26 ALA 209

ASN 121 0.34 GLU 233 -0.26 ALA 209

ASN 121 0.35 LYS 234 -0.29 SER 207

ASN 121 0.30 THR 235 -0.33 SER 207

LYS 117 0.26 GLN 236 -0.27 ALA 209

ASN 121 0.26 ALA 237 -0.28 ALA 209

ASN 121 0.24 VAL 238 -0.32 ASP 70

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A-G226A ***

CA distance fluctuations for 2602071309593453456

--- normal mode 26 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *