Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *

CA distance fluctuations for 2602071335333602968

--- normal mode 18 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASN 121 0.32 ILE 1 -0.47 PRO 23

ASN 121 0.37 VAL 2 -0.47 PRO 23

ASN 121 0.35 GLY 3 -0.41 PRO 23

ASN 121 0.29 GLY 4 -0.39 GLU 198

ASN 121 0.20 THR 5 -0.44 GLU 198

ASN 121 0.14 ALA 6 -0.44 GLU 198

GLN 146 0.07 SER 7 -0.50 GLU 198

ASP 107 0.08 VAL 8 -0.54 GLU 198

THR 144 0.13 ARG 9 -0.49 GLU 198

SER 72 0.16 GLY 10 -0.49 GLU 198

ARG 110 0.06 GLU 11 -0.53 GLU 198

PRO 13 0.11 TRP 12 -0.33 GLU 198

TRP 12 0.11 PRO 13 -0.31 GLY 118

GLY 211 0.08 TRP 14 -0.32 SER 116

GLY 211 0.09 GLN 15 -0.24 SER 116

SER 108 0.14 VAL 16 -0.21 SER 116

GLY 186 0.16 THR 17 -0.19 SER 116

GLY 211 0.16 LEU 18 -0.16 LYS 140

LYS 68 0.18 HIS 19 -0.31 LYS 140

LYS 68 0.27 THR 20 -0.43 LYS 140

GLU 69 0.39 THR 21 -0.62 LYS 140

GLU 69 0.41 SER 22 -0.65 LYS 140

GLU 69 0.66 PRO 23 -0.82 LYS 140

GLU 69 0.89 THR 24 -0.94 LYS 140

LYS 68 0.63 GLN 25 -0.73 LYS 140

LYS 68 0.53 ARG 26 -0.85 ILE 141

LYS 68 0.27 HIS 27 -0.43 ARG 26

LYS 68 0.21 LEU 28 -0.44 CYS 29

GLY 211 0.21 CYS 29 -0.44 LEU 28

GLY 211 0.18 GLY 30 -0.36 GLY 190

GLY 211 0.18 GLY 31 -0.22 LEU 28

GLY 211 0.14 SER 32 -0.23 SER 116

VAL 199 0.15 ILE 33 -0.28 SER 116

VAL 199 0.30 ILE 34 -0.34 LYS 117

ASN 197 0.35 GLY 35 -0.38 LEU 232

ASN 197 0.27 ASN 36 -0.32 GLY 118

ASN 197 0.27 GLN 37 -0.22 SER 72

ASN 197 0.29 TRP 38 -0.19 LEU 232

ASN 197 0.19 ILE 39 -0.18 VAL 228

ASN 197 0.21 LEU 40 -0.19 VAL 228

GLY 211 0.25 THR 41 -0.27 PRO 23

GLY 211 0.33 ALA 42 -0.39 PRO 23

GLY 211 0.35 ALA 43 -0.38 PRO 23

GLY 211 0.43 HIS 44 -0.55 PRO 23

GLY 211 0.38 CYS 45 -0.53 PRO 23

GLY 211 0.34 PHE 46 -0.42 PRO 23

GLY 211 0.39 TYR 47 -0.61 PRO 23

GLY 211 0.34 GLY 48 -0.53 PRO 23

GLY 211 0.31 VAL 49 -0.30 SER 22

GLY 211 0.31 GLU 50 -0.17 SER 22

ILE 81 0.26 SER 51 -0.21 ASP 70

GLY 211 0.21 PRO 52 -0.22 ASP 70

GLU 78 0.24 LYS 53 -0.37 ASP 70

PRO 23 0.20 ILE 54 -0.37 LYS 140

THR 24 0.16 LEU 55 -0.28 LYS 140

THR 24 0.25 ARG 56 -0.27 LYS 140

THR 24 0.20 VAL 57 -0.17 LYS 140

SER 59 0.26 TYR 58 -0.22 ILE 67

TYR 58 0.26 SER 59 -0.25 GLY 118

SER 108 0.27 GLY 60 -0.29 GLY 118

SER 108 0.15 ILE 61 -0.28 GLU 198

GLY 186 0.14 LEU 62 -0.37 GLU 198

GLY 186 0.16 GLN 63 -0.34 GLU 198

GLY 186 0.20 GLN 64 -0.27 GLU 198

HIS 27 0.24 SER 65 -0.34 GLU 69

THR 24 0.31 GLU 66 -0.29 GLU 198

THR 24 0.42 ILE 67 -0.35 PHE 73

THR 24 0.71 LYS 68 -0.30 GLU 69

THR 24 0.89 GLU 69 -0.34 SER 65

THR 24 0.61 ASP 70 -0.37 LYS 53

THR 24 0.56 THR 71 -0.27 PHE 73

THR 24 0.50 SER 72 -0.34 GLY 75

THR 24 0.39 PHE 73 -0.35 ILE 67

THR 24 0.34 PHE 74 -0.30 SER 72

THR 24 0.34 GLY 75 -0.34 SER 72

THR 24 0.19 VAL 76 -0.22 SER 72

LYS 53 0.24 GLN 77 -0.24 SER 72

LYS 53 0.24 GLU 78 -0.18 SER 72

GLY 211 0.25 ILE 79 -0.11 ASP 70

ASN 197 0.26 ILE 80 -0.12 PRO 23

GLY 211 0.29 ILE 81 -0.21 PRO 23

ASN 121 0.29 HIS 82 -0.22 PRO 23

GLY 164 0.30 ASP 83 -0.20 PRO 23

GLY 164 0.38 GLN 84 -0.26 PRO 23

ASN 121 0.36 TYR 85 -0.34 PRO 23

GLU 210 0.37 LYS 86 -0.40 PRO 23

GLU 210 0.42 MET 87 -0.52 PRO 23

ASN 121 0.48 ALA 88 -0.54 PRO 23

ASN 121 0.56 GLU 89 -0.54 PRO 23

ASN 121 0.55 SER 90 -0.47 PRO 23

ASN 121 0.56 GLY 91 -0.41 PRO 23

ASN 121 0.45 TYR 92 -0.35 PRO 23

ASN 121 0.43 ASP 93 -0.40 PRO 23

ASN 121 0.35 ILE 94 -0.31 PRO 23

GLY 211 0.28 ALA 95 -0.24 PRO 23

ASN 197 0.26 LEU 96 -0.15 LEU 28

ASN 197 0.22 LEU 97 -0.14 SER 72

ASN 197 0.26 LYS 98 -0.20 SER 72

ASN 197 0.21 LEU 99 -0.26 SER 72

THR 24 0.27 GLU 100 -0.34 SER 72

THR 24 0.30 THR 101 -0.34 SER 72

THR 24 0.25 THR 102 -0.24 GLY 118

THR 24 0.26 VAL 103 -0.31 GLY 118

THR 24 0.31 GLN 104 -0.39 GLY 118

PHE 73 0.28 TYR 105 -0.47 GLY 118

SER 72 0.32 THR 106 -0.48 GLY 118

SER 72 0.27 ASP 107 -0.49 GLY 118

GLY 60 0.27 SER 108 -0.38 GLY 118

THR 24 0.19 GLN 109 -0.37 GLY 118

PHE 73 0.14 ARG 110 -0.47 SER 116

GLU 198 0.20 PRO 111 -0.45 SER 116

TRP 200 0.26 ILE 112 -0.44 SER 113

ASN 197 0.38 SER 113 -0.44 ILE 112

ASN 197 0.42 LEU 114 -0.49 PRO 115

ASN 197 0.48 PRO 115 -0.49 LEU 114

ASN 197 0.56 SER 116 -0.47 ARG 110

HIS 169 0.46 LYS 117 -0.41 ARG 110

HIS 169 0.57 GLY 118 -0.49 ASP 107

HIS 169 0.51 ASP 119 -0.42 ASP 107

HIS 169 0.78 ARG 120 -0.31 ASP 107

ASN 155 1.13 ASN 121 -0.28 ASP 107

ILE 172 0.54 VAL 122 -0.34 ASP 107

VAL 122 0.26 ILE 123 -0.27 ARG 177

CYS 127 0.22 TYR 124 -0.45 ARG 177

CYS 127 0.14 THR 125 -0.70 ARG 177

GLY 35 0.11 ASP 126 -0.72 ARG 177

ASN 121 0.25 CYS 127 -0.57 ARG 177

ASN 121 0.24 TRP 128 -0.48 ARG 177

ASN 121 0.30 VAL 129 -0.36 PRO 23

ASN 121 0.21 THR 130 -0.36 ARG 26

ASN 121 0.19 GLY 131 -0.39 ARG 26

ASN 121 0.18 TRP 132 -0.53 ARG 26

ASN 121 0.24 GLY 133 -0.57 ARG 26

ASN 121 0.29 TYR 134 -0.65 THR 24

ASN 121 0.33 ARG 135 -0.56 THR 24

GLU 178 0.44 LYS 136 -0.61 PRO 23

ARG 215 0.47 LEU 137 -0.66 PRO 23

ARG 215 0.38 ARG 138 -0.71 PRO 23

GLU 178 0.34 ASP 139 -0.85 THR 24

ARG 215 0.24 LYS 140 -0.94 THR 24

SER 65 0.21 ILE 141 -0.85 ARG 26

ASN 121 0.19 GLN 142 -0.62 ARG 26

ILE 141 0.18 ASN 143 -0.40 ARG 26

ARG 9 0.13 THR 144 -0.35 GLU 198

ARG 9 0.12 LEU 145 -0.34 GLU 198

ASN 121 0.18 GLN 146 -0.37 GLU 198

ASN 121 0.21 LYS 147 -0.41 GLU 198

ASN 121 0.28 ALA 148 -0.42 GLU 198

ASN 121 0.28 LYS 149 -0.53 ARG 177

ASN 121 0.42 ILE 150 -0.63 ARG 177

ASN 121 0.43 PRO 151 -0.69 ARG 177

ASN 121 0.64 LEU 152 -0.46 ARG 177

ASN 121 0.72 VAL 153 -0.35 THR 125

ASN 121 0.92 THR 154 -0.35 PRO 23

ASN 121 1.13 ASN 155 -0.37 PRO 23

ASN 121 0.89 GLU 156 -0.36 PRO 23

ASN 121 0.67 GLU 157 -0.35 PRO 23

ASN 121 0.78 CYS 158 -0.39 PRO 23

ASN 121 0.81 GLN 159 -0.41 PRO 23

ASN 121 0.64 LYS 160 -0.38 PRO 23

ASN 121 0.56 ARG 161 -0.40 PRO 23

ASN 121 0.65 TYR 162 -0.44 PRO 23

ASN 121 0.64 ARG 163 -0.43 PRO 23

ASN 121 0.59 GLY 164 -0.48 PRO 23

ASN 121 0.67 HIS 165 -0.50 PRO 23

ASN 121 0.77 LYS 166 -0.46 PRO 23

ASN 121 0.88 ILE 167 -0.43 PRO 23

ASN 121 0.94 THR 168 -0.39 PRO 23

ASN 121 1.03 HIS 169 -0.33 PRO 23

ASN 121 0.76 LYS 170 -0.33 PRO 23

ASN 121 0.89 MET 171 -0.39 PRO 23

ASN 121 0.95 ILE 172 -0.37 PRO 23

ASN 121 0.84 CYS 173 -0.41 PRO 23

ASN 121 0.64 ALA 174 -0.39 PRO 23

ASN 121 0.55 GLY 175 -0.61 ILE 150

ASN 121 0.44 TYR 176 -0.72 ARG 177

ASN 121 0.30 ARG 177 -0.72 TYR 176

LYS 136 0.44 GLU 178 -0.53 ASN 197

ASN 121 0.42 GLY 179 -0.42 GLU 198

LYS 136 0.42 GLY 180 -0.41 GLU 198

ASN 121 0.42 LYS 181 -0.40 PRO 23

ASN 121 0.46 ASP 182 -0.44 PRO 23

ASN 121 0.40 ALA 183 -0.48 PRO 23

ASN 121 0.38 CYS 184 -0.58 PRO 23

ASN 121 0.30 LYS 185 -0.68 PRO 23

ASN 121 0.24 GLY 186 -0.62 PRO 23

ASN 121 0.27 ASP 187 -0.50 PRO 23

ASN 121 0.31 SER 188 -0.52 PRO 23

ASN 121 0.27 GLY 189 -0.39 PRO 23

ASN 121 0.23 GLY 190 -0.36 GLY 30

ASN 121 0.22 PRO 191 -0.30 PRO 23

ASN 121 0.30 LEU 192 -0.32 PRO 23

ASN 121 0.14 SER 193 -0.37 ARG 177

THR 235 0.12 CYS 194 -0.48 ARG 177

THR 235 0.15 LYS 195 -0.56 ARG 177

PRO 115 0.27 HIS 196 -0.49 ARG 177

SER 116 0.56 ASN 197 -0.60 ARG 177

GLN 236 0.36 GLU 198 -0.60 ARG 177

SER 113 0.33 VAL 199 -0.41 ARG 177

ILE 34 0.27 TRP 200 -0.39 ARG 177

ASN 197 0.22 HIS 201 -0.34 ASP 107

LEU 96 0.18 LEU 202 -0.26 ARG 177

ASN 121 0.28 VAL 203 -0.25 ARG 177

ASN 121 0.41 GLY 204 -0.30 PRO 23

ASN 121 0.38 ILE 205 -0.35 PRO 23

ASN 121 0.41 THR 206 -0.45 PRO 23

ASN 121 0.50 SER 207 -0.53 PRO 23

ASN 121 0.54 TRP 208 -0.61 PRO 23

ASN 121 0.56 ALA 209 -0.54 PRO 23

ASN 121 0.50 GLU 210 -0.50 PRO 23

ASN 121 0.47 GLY 211 -0.47 PRO 23

ASN 121 0.47 CYS 212 -0.47 PRO 23

ASN 121 0.44 ALA 213 -0.39 PRO 23

ARG 215 0.45 GLN 214 -0.35 PRO 23

LEU 137 0.47 ARG 215 -0.39 GLU 198

ASN 121 0.40 GLU 216 -0.46 ASP 126

ASN 121 0.53 ARG 217 -0.40 PRO 23

ASN 121 0.59 PRO 218 -0.43 PRO 23

ASN 121 0.61 ALA 219 -0.49 PRO 23

ASN 121 0.71 VAL 220 -0.47 PRO 23

ASN 121 0.62 TYR 221 -0.43 PRO 23

ASN 121 0.57 THR 222 -0.37 PRO 23

ASN 121 0.62 ASN 223 -0.30 PRO 23

ASN 121 0.36 VAL 224 -0.25 PRO 23

ASN 197 0.30 VAL 225 -0.24 ASP 107

ASN 121 0.36 GLU 226 -0.22 PRO 23

ASN 197 0.31 TYR 227 -0.23 ILE 34

ASN 197 0.42 VAL 228 -0.33 ILE 34

ASN 197 0.40 ASP 229 -0.30 GLY 35

ASN 197 0.35 TRP 230 -0.24 GLY 35

ASN 197 0.39 ILE 231 -0.29 GLY 35

ASN 197 0.46 LEU 232 -0.38 GLY 35

ASN 197 0.40 GLU 233 -0.26 GLY 35

ASN 197 0.38 LYS 234 -0.20 GLY 35

ASN 197 0.43 THR 235 -0.25 GLY 35

ASN 197 0.44 GLN 236 -0.30 ASN 36

ASN 197 0.38 ALA 237 -0.25 ASN 36

ASN 197 0.36 VAL 238 -0.24 ASN 36

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** FXIa G216A-G226A ***

CA distance fluctuations for 2602071335333602968

--- normal mode 18 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* FXIa G216A-G226A *