Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* *

CA distance fluctuations for 260211153256928911

--- normal mode 11 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASP 64 0.07 MET 1 -0.10 GLY 46

ASP 64 0.08 ALA 2 -0.10 GLY 27

ASP 64 0.09 LEU 3 -0.10 GLY 46

SER 57 0.09 GLY 4 -0.10 GLY 46

SER 57 0.10 ASP 5 -0.09 GLY 46

SER 57 0.12 PRO 6 -0.08 GLY 46

SER 57 0.13 ILE 7 -0.08 GLY 46

SER 57 0.14 GLN 8 -0.07 GLY 46

SER 57 0.16 VAL 9 -0.07 LYS 35

SER 57 0.17 ARG 10 -0.06 LYS 35

SER 57 0.20 LEU 11 -0.07 LYS 35

SER 57 0.21 SER 12 -0.06 LYS 35

SER 57 0.24 PRO 13 -0.06 LYS 35

SER 57 0.27 GLU 14 -0.06 LYS 35

SER 57 0.26 LYS 15 -0.07 LYS 35

SER 57 0.25 GLN 16 -0.06 LYS 35

SER 57 0.29 ALA 17 -0.06 LYS 35

SER 57 0.32 LEU 18 -0.07 LYS 35

SER 57 0.28 LEU 19 -0.07 LYS 35

SER 57 0.28 GLU 20 -0.06 LYS 35

SER 57 0.34 ASP 21 -0.06 LYS 35

SER 57 0.33 GLU 22 -0.07 LYS 35

SER 57 0.27 ALA 23 -0.07 LYS 35

HIS 60 0.31 ALA 24 -0.06 LYS 35

HIS 60 0.36 ARG 25 -0.07 LYS 35

HIS 60 0.30 LYS 26 -0.07 LYS 35

HIS 60 0.28 GLY 27 -0.07 LYS 35

HIS 60 0.24 LYS 28 -0.07 LYS 35

HIS 60 0.22 ARG 29 -0.06 LYS 35

SER 57 0.22 LEU 30 -0.06 LYS 35

SER 57 0.18 ALA 31 -0.07 LYS 35

HIS 60 0.18 THR 32 -0.07 LYS 35

VAL 56 0.20 TYR 33 -0.08 LYS 35

SER 57 0.18 LEU 34 -0.08 LYS 35

SER 57 0.15 ARG 35 -0.08 LYS 35

VAL 56 0.15 GLU 36 -0.09 LYS 35

ALA 49 0.17 LEU 37 -0.09 LYS 35

ALA 49 0.14 LEU 38 -0.09 GLY 46

VAL 56 0.11 GLU 39 -0.10 GLY 46

ALA 49 0.11 SER 40 -0.10 ALA 36

GLY 46 0.10 GLU 41 -0.14 LEU 44

LYS 28 0.10 ASN 42 -0.12 GLY 46

GLU 47 0.16 ASP 43 -0.11 ASN 238

GLU 47 0.10 LEU 44 -0.12 ASN 238

LEU 37 0.11 GLN 45 -0.13 LEU 48

ASP 43 0.09 GLY 46 -0.12 ASN 238

ASP 43 0.16 GLU 47 -0.13 ASN 238

GLN 45 0.10 LEU 48 -0.13 GLN 45

ARG 25 0.11 ALA 49 -0.13 ASN 238

ARG 25 0.17 ALA 50 -0.13 ASN 238

GLU 22 0.17 LEU 51 -0.16 ARG 25

ARG 25 0.15 ARG 52 -0.19 GLU 22

ARG 25 0.18 ARG 53 -0.18 ARG 25

ARG 25 0.22 GLU 54 -0.19 ARG 25

ARG 25 0.19 VAL 55 -0.24 ARG 25

ARG 25 0.18 VAL 56 -0.25 ARG 25

ARG 25 0.23 SER 57 -0.23 ARG 25

ARG 25 0.24 LEU 58 -0.26 ARG 25

ARG 25 0.20 HIS 59 -0.30 ARG 25

ARG 25 0.21 HIS 60 -0.28 ARG 25

ARG 25 0.25 VAL 61 -0.26 ARG 25

ARG 25 0.23 ILE 62 -0.30 ARG 25

ARG 25 0.20 GLU 63 -0.32 ARG 25

ARG 25 0.23 ASP 64 -0.29 ARG 25

ARG 25 0.24 LEU 65 -0.29 ARG 25

ARG 25 0.21 ALA 66 -0.33 ARG 25

ARG 25 0.21 ASP 67 -0.31 ARG 25

ARG 25 0.23 THR 68 -0.28 ARG 25

ARG 25 0.23 GLY 69 -0.30 ARG 25

ARG 25 0.20 LEU 70 -0.32 ARG 25

ARG 25 0.21 ARG 71 -0.29 ARG 25

ARG 25 0.23 SER 72 -0.27 ARG 25

ARG 25 0.22 ASP 73 -0.29 ARG 25

ARG 25 0.22 GLN 74 -0.26 ARG 25

ARG 25 0.21 SER 75 -0.25 ARG 25

ARG 25 0.22 GLY 76 -0.25 ARG 25

ARG 25 0.21 PRO 77 -0.24 ARG 25

ASP 21 0.20 GLY 78 -0.23 ARG 25

ARG 25 0.20 GLN 79 -0.23 ARG 25

ARG 25 0.20 ASN 80 -0.22 ARG 25

ASP 21 0.19 ALA 81 -0.22 ASP 236

ARG 25 0.18 VAL 82 -0.22 ARG 25

ARG 25 0.18 GLN 83 -0.21 ARG 25

ARG 25 0.18 ILE 84 -0.21 GLU 275

ASP 21 0.17 GLU 85 -0.23 GLU 275

ARG 25 0.17 THR 86 -0.20 PRO 273

ARG 25 0.17 LEU 87 -0.20 PRO 273

ARG 25 0.16 LEU 88 -0.24 PRO 273

ARG 25 0.16 LEU 89 -0.25 PRO 273

ARG 25 0.16 LEU 90 -0.21 PRO 273

ARG 25 0.16 ARG 91 -0.23 PRO 273

ALA 24 0.15 ALA 92 -0.27 PRO 273

ARG 25 0.15 ILE 93 -0.24 PRO 273

ARG 25 0.15 ALA 94 -0.21 PRO 273

ALA 24 0.15 GLY 95 -0.26 PRO 273

ALA 24 0.15 PRO 96 -0.27 GLU 274

ALA 24 0.15 GLU 97 -0.24 GLU 274

ALA 24 0.15 ARG 98 -0.21 GLU 274

ALA 24 0.16 MET 99 -0.22 GLU 274

ALA 24 0.16 LYS 100 -0.22 GLU 274

ALA 24 0.16 PRO 101 -0.19 GLU 274

ARG 25 0.17 VAL 102 -0.19 GLU 275

ALA 24 0.17 LYS 103 -0.21 GLU 275

ALA 24 0.17 GLY 104 -0.20 GLU 275

ALA 24 0.17 GLU 105 -0.18 GLU 275

ARG 25 0.18 LEU 106 -0.19 GLU 275

ALA 24 0.18 LYS 107 -0.20 GLU 275

ALA 17 0.18 ARG 108 -0.18 GLU 275

ALA 17 0.19 LEU 109 -0.17 GLU 275

ALA 24 0.20 GLY 110 -0.18 LYS 277

ARG 25 0.20 ILE 111 -0.18 GLU 275

ALA 24 0.20 GLU 112 -0.20 GLU 275

ALA 24 0.19 VAL 113 -0.21 GLU 275

ARG 25 0.19 TRP 114 -0.21 GLU 275

ALA 24 0.18 THR 115 -0.24 GLU 275

ALA 24 0.18 PRO 116 -0.26 GLU 275

ALA 24 0.19 GLU 117 -0.26 LYS 277

ALA 24 0.20 GLY 118 -0.23 LYS 277

ALA 24 0.19 LYS 119 -0.24 LYS 277

ALA 24 0.18 GLU 120 -0.25 GLU 275

ALA 24 0.17 ASP 121 -0.27 LYS 277

SER 57 0.19 MET 1 -0.09 SER 95

SER 57 0.19 ALA 2 -0.08 LYS 97

SER 57 0.19 LEU 3 -0.07 SER 95

SER 57 0.21 GLY 4 -0.06 SER 95

SER 57 0.20 ASP 5 -0.05 SER 95

SER 57 0.18 PRO 6 -0.05 LYS 35

SER 57 0.18 ILE 7 -0.06 LYS 35

SER 57 0.16 GLN 8 -0.06 LYS 35

SER 57 0.15 VAL 9 -0.07 GLY 46

SER 57 0.13 ARG 10 -0.09 GLY 46

SER 57 0.11 LEU 11 -0.10 GLY 46

SER 57 0.09 SER 12 -0.11 GLY 46

SER 57 0.07 PRO 13 -0.12 GLY 46

LYS 28 0.07 GLU 14 -0.14 GLY 46

GLY 46 0.09 LYS 15 -0.14 GLY 46

GLY 46 0.10 GLN 16 -0.12 GLY 46

GLY 46 0.09 ALA 17 -0.14 GLY 46

GLY 46 0.10 LEU 18 -0.16 GLY 46

GLY 46 0.13 LEU 19 -0.14 GLY 46

GLY 46 0.11 GLU 20 -0.13 GLY 46

GLY 46 0.11 ASP 21 -0.14 GLY 46

GLY 46 0.14 GLU 22 -0.14 GLY 46

GLY 46 0.14 ALA 23 -0.12 GLY 46

GLY 46 0.12 ALA 24 -0.11 GLY 46

GLY 46 0.13 ARG 25 -0.12 GLY 46

GLY 46 0.15 LYS 26 -0.11 GLY 46

GLY 46 0.13 GLY 27 -0.10 GLY 46

GLY 46 0.13 LYS 28 -0.10 GLY 46

GLY 46 0.12 ARG 29 -0.10 GLY 46

GLY 46 0.13 LEU 30 -0.11 GLY 46

GLY 46 0.13 ALA 31 -0.09 GLY 46

GLY 46 0.15 THR 32 -0.09 GLY 46

GLY 46 0.16 TYR 33 -0.10 GLY 46

GLY 46 0.17 LEU 34 -0.10 GLY 46

GLY 46 0.19 ARG 35 -0.08 LYS 35

GLY 46 0.22 GLU 36 -0.09 LYS 35

GLY 46 0.18 LEU 37 -0.12 GLY 46

GLY 46 0.21 LEU 38 -0.09 LYS 35

GLY 46 0.23 GLU 39 -0.09 LYS 35

GLY 46 0.25 SER 40 -0.12 GLN 45

GLY 46 0.29 GLU 41 -0.11 GLN 45

GLY 46 0.51 ASN 42 -0.10 LYS 35

GLY 46 0.36 ASP 43 -0.11 ASP 99

GLY 46 0.15 LEU 44 -0.13 ASP 99

ALA 49 0.26 GLN 45 -0.11 ASP 99

ASN 42 0.51 GLY 46 -0.13 ASN 238

ASP 43 0.23 GLU 47 -0.14 ASP 99

GLN 45 0.26 LEU 48 -0.13 ASN 238

ASN 42 0.27 ALA 49 -0.14 ASN 238

LEU 18 0.28 ALA 50 -0.14 ASN 238

LEU 18 0.21 LEU 51 -0.16 ARG 25

GLU 22 0.25 ARG 52 -0.15 ARG 25

GLU 22 0.32 ARG 53 -0.15 ARG 25

LEU 18 0.26 GLU 54 -0.19 ARG 25

ARG 25 0.25 VAL 55 -0.20 ARG 25

ARG 25 0.34 VAL 56 -0.18 ARG 25

ARG 25 0.34 SER 57 -0.19 ARG 25

ARG 25 0.28 LEU 58 -0.23 ARG 25

ARG 25 0.31 HIS 59 -0.22 ARG 25

ARG 25 0.36 HIS 60 -0.20 ARG 25

ARG 25 0.31 VAL 61 -0.23 ARG 25

ARG 25 0.28 ILE 62 -0.25 ARG 25

ARG 25 0.31 GLU 63 -0.23 ARG 25

ARG 25 0.34 ASP 64 -0.22 ARG 25

ARG 25 0.29 LEU 65 -0.25 ARG 25

ARG 25 0.28 ALA 66 -0.25 ARG 25

ARG 25 0.31 ASP 67 -0.23 ARG 25

ARG 25 0.29 THR 68 -0.24 ARG 25

ARG 25 0.26 GLY 69 -0.26 ARG 25

ARG 25 0.27 LEU 70 -0.25 ARG 25

ARG 25 0.28 ARG 71 -0.23 ARG 25

ARG 25 0.26 SER 72 -0.24 ARG 25

ARG 25 0.24 ASP 73 -0.25 ARG 25

ARG 25 0.25 GLN 74 -0.23 ARG 25

ARG 25 0.23 SER 75 -0.22 ARG 25

ARG 25 0.24 GLY 76 -0.21 ARG 25

ARG 25 0.23 PRO 77 -0.20 ARG 25

ARG 25 0.22 GLY 78 -0.19 ARG 25

ARG 25 0.21 GLN 79 -0.20 ARG 25

ARG 25 0.21 ASN 80 -0.20 ARG 25

ARG 25 0.20 ALA 81 -0.19 ARG 25

ARG 25 0.19 VAL 82 -0.19 ARG 25

ARG 25 0.19 GLN 83 -0.19 ARG 25

ARG 25 0.19 ILE 84 -0.18 ARG 25

ARG 25 0.18 GLU 85 -0.18 ARG 25

ARG 25 0.18 THR 86 -0.18 ARG 25

ARG 25 0.17 LEU 87 -0.18 ARG 25

ARG 25 0.17 LEU 88 -0.17 ARG 25

ARG 25 0.16 LEU 89 -0.17 ARG 25

ARG 25 0.16 LEU 90 -0.17 ARG 25

ARG 25 0.16 ARG 91 -0.16 ARG 25

ARG 25 0.16 ALA 92 -0.16 ARG 25

ARG 25 0.15 ILE 93 -0.16 ARG 25

ARG 25 0.15 ALA 94 -0.16 ARG 25

ARG 25 0.15 GLY 95 -0.15 ARG 25

ARG 25 0.15 PRO 96 -0.15 ARG 25

ARG 25 0.14 GLU 97 -0.14 ARG 25

ARG 25 0.14 ARG 98 -0.15 ARG 25

ARG 25 0.15 MET 99 -0.15 ARG 25

ASP 21 0.15 LYS 100 -0.14 ARG 25

ALA 24 0.15 PRO 101 -0.14 ASP 21

ASP 21 0.16 VAL 102 -0.15 ARG 25

ASP 21 0.16 LYS 103 -0.15 ARG 25

ALA 24 0.16 GLY 104 -0.14 ASP 21

ALA 24 0.16 GLU 105 -0.15 ASP 21

ASP 21 0.17 LEU 106 -0.15 ASP 21

ALA 24 0.18 LYS 107 -0.14 ASP 21

ALA 24 0.17 ARG 108 -0.14 ASP 21

ALA 24 0.18 LEU 109 -0.15 ASP 21

ALA 24 0.19 GLY 110 -0.14 ASP 21

ASP 21 0.19 ILE 111 -0.15 ASP 21

ASP 21 0.19 GLU 112 -0.15 ARG 25

ASP 21 0.18 VAL 113 -0.15 ARG 25

ASP 21 0.19 TRP 114 -0.16 ARG 25

ALA 17 0.19 THR 115 -0.15 ARG 25

ALA 17 0.19 PRO 116 -0.16 GLU 275

ALA 17 0.20 GLU 117 -0.15 LYS 35

ASP 21 0.20 GLY 118 -0.15 ARG 25

ASP 21 0.20 LYS 119 -0.14 ARG 25

ALA 17 0.18 GLU 120 -0.14 ARG 25

ALA 17 0.18 ASP 121 -0.13 LYS 35

GLU 31 0.11 MET 1 -0.16 ASP 99

GLU 31 0.05 ALA 2 -0.16 ASP 99

GLN 39 0.05 LEU 3 -0.16 ASP 99

GLY 46 0.07 GLY 4 -0.15 ASP 99

GLY 46 0.07 ASP 5 -0.15 ASP 99

GLY 46 0.05 PRO 6 -0.17 ASP 64

GLY 46 0.06 ILE 7 -0.16 SER 57

GLY 46 0.05 GLN 8 -0.18 SER 57

ASN 93 0.05 VAL 9 -0.19 SER 57

ASN 93 0.06 ARG 10 -0.19 SER 57

SER 95 0.07 LEU 11 -0.21 SER 57

SER 95 0.07 SER 12 -0.22 ASP 67

SER 95 0.07 PRO 13 -0.26 ASP 67

SER 95 0.08 GLU 14 -0.28 SER 57

SER 95 0.08 LYS 15 -0.27 SER 57

SER 95 0.08 GLN 16 -0.28 SER 57

ASN 93 0.09 ALA 17 -0.33 SER 57

SER 95 0.10 LEU 18 -0.36 SER 57

SER 95 0.10 LEU 19 -0.33 SER 57

ASN 93 0.10 GLU 20 -0.34 SER 57

ASN 93 0.11 ASP 21 -0.41 SER 57

SER 95 0.12 GLU 22 -0.41 ARG 53

ASN 93 0.12 ALA 23 -0.35 SER 57

ASN 93 0.13 ALA 24 -0.39 HIS 60

ASN 93 0.14 ARG 25 -0.46 HIS 60

ASN 93 0.15 LYS 26 -0.41 VAL 56

ASN 93 0.15 GLY 27 -0.38 HIS 60

ASN 93 0.14 LYS 28 -0.32 HIS 60

ASN 93 0.12 ARG 29 -0.29 HIS 60

ASN 93 0.10 LEU 30 -0.28 SER 57

ASN 93 0.09 ALA 31 -0.24 SER 57

ASN 93 0.11 THR 32 -0.24 VAL 56

SER 95 0.11 TYR 33 -0.27 VAL 56

GLN 39 0.09 LEU 34 -0.23 SER 57

GLN 39 0.10 ARG 35 -0.20 VAL 56

GLN 39 0.12 GLU 36 -0.21 VAL 56

GLN 39 0.11 LEU 37 -0.21 ALA 49

GLN 39 0.08 LEU 38 -0.17 ALA 49

GLN 39 0.09 GLU 39 -0.15 ASP 99

GLN 39 0.11 SER 40 -0.15 ASP 99

GLY 46 0.10 GLU 41 -0.14 ASP 99

MET 1 0.11 ASN 42 -0.14 ASP 99

LYS 97 0.13 ASP 43 -0.23 GLU 47

LYS 97 0.11 LEU 44 -0.14 ASP 99

MET 1 0.12 GLN 45 -0.13 ASP 99

LYS 97 0.14 GLY 46 -0.15 ASP 43

LYS 97 0.13 GLU 47 -0.23 ASP 43

GLU 99 0.14 LEU 48 -0.15 LYS 26

GLU 99 0.16 ALA 49 -0.16 LYS 26

GLU 99 0.16 ALA 50 -0.24 LYS 26

GLU 99 0.15 LEU 51 -0.24 LYS 26

GLU 99 0.16 ARG 52 -0.20 LYS 26

GLU 99 0.18 ARG 53 -0.24 LYS 26

GLU 99 0.17 GLU 54 -0.29 ARG 25

LEU 18 0.18 VAL 55 -0.26 ARG 25

LEU 18 0.21 VAL 56 -0.24 ARG 25

GLU 99 0.18 SER 57 -0.30 ARG 25

ASP 21 0.19 LEU 58 -0.31 ARG 25

LEU 18 0.23 HIS 59 -0.26 ARG 25

LEU 18 0.22 HIS 60 -0.27 ARG 25

ASP 21 0.20 VAL 61 -0.32 ARG 25

ARG 25 0.23 ILE 62 -0.29 ARG 25

ASP 21 0.25 GLU 63 -0.26 ARG 25

ASP 21 0.23 ASP 64 -0.29 ARG 25

ARG 25 0.22 LEU 65 -0.31 ARG 25

ARG 25 0.26 ALA 66 -0.27 ARG 25

ASP 21 0.26 ASP 67 -0.26 ARG 25

ASP 21 0.23 THR 68 -0.29 ARG 25

ARG 25 0.24 GLY 69 -0.29 ARG 25

ARG 25 0.26 LEU 70 -0.26 ARG 25

ASP 21 0.24 ARG 71 -0.27 ARG 25

ARG 25 0.22 SER 72 -0.29 ARG 25

ARG 25 0.23 ASP 73 -0.28 ARG 25

ASP 21 0.22 GLN 74 -0.27 ARG 25

ARG 25 0.20 SER 75 -0.28 ARG 25

ASP 21 0.19 GLY 76 -0.29 ARG 25

ASP 21 0.18 PRO 77 -0.27 ARG 25

ASP 21 0.17 GLY 78 -0.27 ARG 25

ARG 25 0.18 GLN 79 -0.27 ARG 25

ASP 21 0.18 ASN 80 -0.26 ARG 25

ASP 21 0.17 ALA 81 -0.25 ARG 25

ASP 21 0.16 VAL 82 -0.25 ARG 25

ARG 25 0.17 GLN 83 -0.24 ARG 25

ASP 21 0.16 ILE 84 -0.24 ARG 25

ASP 21 0.15 GLU 85 -0.23 ARG 25

ARG 25 0.15 THR 86 -0.22 ARG 25

ASP 21 0.15 LEU 87 -0.22 ARG 25

ASP 21 0.14 LEU 88 -0.22 ASP 236

ASP 21 0.14 LEU 89 -0.21 ARG 25

ASP 21 0.14 LEU 90 -0.20 PRO 273

ASP 21 0.14 ARG 91 -0.26 PRO 273

ASP 21 0.13 ALA 92 -0.27 PRO 273

ASP 21 0.13 ILE 93 -0.23 PRO 273

ASP 21 0.14 ALA 94 -0.28 PRO 273

ASP 21 0.13 GLY 95 -0.36 PRO 273

ASP 21 0.13 PRO 96 -0.41 PRO 273

ASP 21 0.13 GLU 97 -0.43 PRO 273

ASP 21 0.14 ARG 98 -0.35 PRO 273

ASP 21 0.14 MET 99 -0.33 PRO 273

ASP 21 0.14 LYS 100 -0.37 GLU 275

ALA 24 0.15 PRO 101 -0.33 GLU 275

ASP 21 0.15 VAL 102 -0.29 GLU 275

ASP 21 0.15 LYS 103 -0.31 GLU 275

ASP 21 0.15 GLY 104 -0.33 GLU 275

ALA 24 0.16 GLU 105 -0.29 GLU 275

ASP 21 0.17 LEU 106 -0.27 GLU 275

ASP 21 0.16 LYS 107 -0.29 LYS 277

ASP 21 0.16 ARG 108 -0.29 LYS 277

ASP 21 0.18 LEU 109 -0.26 LYS 277

ASP 21 0.18 GLY 110 -0.26 LYS 277

ASP 21 0.18 ILE 111 -0.24 LYS 277

ASP 21 0.16 GLU 112 -0.26 ASN 238

ASP 21 0.16 VAL 113 -0.27 ASP 236

ASP 21 0.16 TRP 114 -0.26 ASP 236

ASP 21 0.14 THR 115 -0.29 ASP 236

ASP 21 0.14 PRO 116 -0.28 ASN 238

ALA 17 0.13 GLU 117 -0.29 ASN 238

ALA 17 0.15 GLY 118 -0.28 ASN 238

ALA 17 0.14 LYS 119 -0.32 ASN 238

ALA 17 0.13 GLU 120 -0.35 ASN 238

ALA 17 0.12 ASP 121 -0.40 ASN 238

SER 95 0.06 MET 1 -0.23 ASP 64

ASN 93 0.06 ALA 2 -0.23 ASP 64

ASN 93 0.06 LEU 3 -0.22 ASP 67

ASN 93 0.07 GLY 4 -0.24 ASP 67

ASN 93 0.07 ASP 5 -0.23 ASP 64

ASN 93 0.06 PRO 6 -0.21 ASP 64

ASN 93 0.07 ILE 7 -0.22 SER 57

ASN 93 0.06 GLN 8 -0.20 ASP 64

ASN 93 0.07 VAL 9 -0.20 SER 57

GLN 39 0.06 ARG 10 -0.17 SER 57

GLN 39 0.06 LEU 11 -0.16 ASP 99

GLY 46 0.07 SER 12 -0.15 ASP 99

GLY 46 0.08 PRO 13 -0.14 ASP 99

GLY 46 0.10 GLU 14 -0.13 ASP 99

GLY 46 0.10 LYS 15 -0.14 ASP 99

GLY 46 0.09 GLN 16 -0.14 ASP 99

GLY 46 0.11 ALA 17 -0.12 ASP 99

GLY 46 0.13 LEU 18 -0.12 ASP 99

GLY 46 0.11 LEU 19 -0.14 GLY 46

GLY 46 0.10 GLU 20 -0.12 GLY 46

GLY 46 0.12 ASP 21 -0.12 GLY 46

GLY 46 0.13 GLU 22 -0.14 GLY 46

GLY 46 0.11 ALA 23 -0.14 GLY 46

GLY 46 0.11 ALA 24 -0.12 GLY 46

GLY 46 0.12 ARG 25 -0.12 GLY 46

GLY 46 0.12 LYS 26 -0.14 GLY 46

GLY 46 0.10 GLY 27 -0.12 GLY 46

GLY 46 0.11 LYS 28 -0.13 PRO 18

GLY 46 0.10 ARG 29 -0.15 PRO 18

GLY 46 0.09 LEU 30 -0.15 PRO 18

GLY 46 0.08 ALA 31 -0.14 SER 57

GLY 46 0.08 THR 32 -0.14 GLY 46

GLY 46 0.10 TYR 33 -0.15 GLY 46

GLY 46 0.08 LEU 34 -0.17 GLY 46

GLY 46 0.07 ARG 35 -0.18 GLY 46

GLN 45 0.09 GLU 36 -0.19 GLY 46

GLN 45 0.11 LEU 37 -0.18 GLY 46

SER 95 0.08 LEU 38 -0.21 GLY 46

SER 95 0.08 GLU 39 -0.22 GLY 46

GLN 45 0.11 SER 40 -0.23 GLY 46

LYS 97 0.08 GLU 41 -0.29 GLY 46

LYS 97 0.09 ASN 42 -0.51 GLY 46

LYS 97 0.08 ASP 43 -0.30 GLY 46

LYS 97 0.09 LEU 44 -0.14 GLU 41

LYS 97 0.10 GLN 45 -0.26 LEU 48

SER 199 0.09 GLY 46 -0.51 ASN 42

ASP 98 0.10 GLU 47 -0.20 ASN 42

ASP 98 0.11 LEU 48 -0.26 GLN 45

ASP 98 0.11 ALA 49 -0.32 GLU 22

ASP 98 0.11 ALA 50 -0.32 GLU 22

GLU 99 0.12 LEU 51 -0.26 GLU 22

ASP 98 0.13 ARG 52 -0.32 GLU 22

ASP 98 0.12 ARG 53 -0.41 GLU 22

ARG 25 0.13 GLU 54 -0.34 ARG 25

ARG 25 0.14 VAL 55 -0.35 ARG 25

GLY 198 0.13 VAL 56 -0.45 ARG 25

ARG 25 0.13 SER 57 -0.45 ARG 25

ARG 25 0.17 LEU 58 -0.38 ARG 25

ARG 25 0.16 HIS 59 -0.40 ARG 25

ARG 25 0.15 HIS 60 -0.46 ARG 25

ARG 25 0.17 VAL 61 -0.40 ARG 25

ARG 25 0.19 ILE 62 -0.36 ARG 25

ARG 25 0.17 GLU 63 -0.40 ARG 25

GLY 118 0.18 ASP 64 -0.43 ARG 25

ARG 25 0.20 LEU 65 -0.37 ARG 25

ARG 25 0.20 ALA 66 -0.35 ARG 25

GLY 118 0.20 ASP 67 -0.39 ARG 25

GLY 118 0.19 THR 68 -0.37 ARG 25

ARG 25 0.21 GLY 69 -0.33 ARG 25

ARG 25 0.20 LEU 70 -0.33 ARG 25

GLY 118 0.20 ARG 71 -0.34 ARG 25

ARG 25 0.20 SER 72 -0.32 ARG 25

ARG 25 0.21 ASP 73 -0.30 ARG 25

ARG 25 0.20 GLN 74 -0.30 ARG 25

ARG 25 0.19 SER 75 -0.29 ARG 25

GLY 118 0.19 GLY 76 -0.30 ARG 25

GLY 118 0.24 PRO 77 -0.29 ARG 25

TRP 114 0.17 GLY 78 -0.27 ARG 25

ARG 25 0.18 GLN 79 -0.27 ARG 25

ARG 25 0.18 ASN 80 -0.26 ARG 25

ARG 25 0.16 ALA 81 -0.25 ARG 25

ARG 25 0.17 VAL 82 -0.24 ARG 25

ARG 25 0.17 GLN 83 -0.24 ARG 25

ARG 25 0.16 ILE 84 -0.24 ARG 25

ARG 25 0.16 GLU 85 -0.22 ALA 24

ARG 25 0.15 THR 86 -0.22 ARG 25

ARG 25 0.15 LEU 87 -0.22 ARG 25

ARG 25 0.15 LEU 88 -0.21 ARG 25

ARG 25 0.14 LEU 89 -0.20 ALA 24

ARG 25 0.14 LEU 90 -0.20 ARG 25

ASP 21 0.13 ARG 91 -0.21 ARG 25

ARG 25 0.13 ALA 92 -0.19 ALA 24

ARG 25 0.13 ILE 93 -0.18 ALA 24

ASP 21 0.12 ALA 94 -0.19 ARG 25

ASP 21 0.12 GLY 95 -0.19 ARG 25

ASP 21 0.11 PRO 96 -0.19 ARG 25

ASP 21 0.10 GLU 97 -0.27 ARG 121

ASP 21 0.11 ARG 98 -0.22 ALA 92

ASP 21 0.11 MET 99 -0.21 ARG 25

ASP 21 0.11 LYS 100 -0.29 SER 232

ASP 21 0.11 PRO 101 -0.31 SER 232

ASP 21 0.12 VAL 102 -0.24 ASP 236

ASP 21 0.12 LYS 103 -0.25 ASP 227

ASP 21 0.12 GLY 104 -0.29 ASP 236

ASP 21 0.12 GLU 105 -0.28 ASP 236

ASP 21 0.13 LEU 106 -0.24 ARG 25

ASP 21 0.12 LYS 107 -0.27 ASP 227

ALA 17 0.12 ARG 108 -0.29 ASN 238

ASP 21 0.13 LEU 109 -0.26 ASN 238

ASP 21 0.14 GLY 110 -0.26 ARG 25

ASP 21 0.15 ILE 111 -0.26 ARG 25

ASP 21 0.14 GLU 112 -0.25 ARG 25

ASP 21 0.14 VAL 113 -0.25 ASP 227

ASP 21 0.15 TRP 114 -0.25 ARG 25

GLU 99 0.15 THR 115 -0.23 ARG 25

GLU 99 0.15 PRO 116 -0.23 ARG 25

GLU 99 0.16 GLU 117 -0.23 GLY 27

GLU 99 0.15 GLY 118 -0.25 ARG 25

GLU 99 0.15 LYS 119 -0.24 GLY 226

GLU 99 0.14 GLU 120 -0.30 GLY 226

GLU 99 0.13 ASP 121 -0.34 GLY 226

GLY 46 0.06 MET 1 -0.12 GLY 46

GLY 46 0.06 ALA 2 -0.11 HIS 16

GLY 46 0.07 LEU 3 -0.10 SER 57

GLY 46 0.07 GLY 4 -0.10 ASP 99

GLY 46 0.07 ASP 5 -0.10 SER 57

GLY 46 0.06 PRO 6 -0.11 SER 57

GLY 46 0.07 ILE 7 -0.11 SER 57

GLY 46 0.06 GLN 8 -0.12 SER 57

GLY 46 0.06 VAL 9 -0.12 SER 57

GLY 46 0.05 ARG 10 -0.12 SER 57

LYS 26 0.05 LEU 11 -0.13 SER 57

LYS 26 0.05 SER 12 -0.14 SER 57

SER 95 0.04 PRO 13 -0.16 SER 57

SER 95 0.05 GLU 14 -0.18 SER 57

SER 95 0.05 LYS 15 -0.18 SER 57

SER 95 0.05 GLN 16 -0.18 SER 57

SER 95 0.05 ALA 17 -0.22 SER 57

SER 95 0.06 LEU 18 -0.24 SER 57

SER 95 0.05 LEU 19 -0.22 SER 57

SER 95 0.05 GLU 20 -0.23 SER 57

SER 95 0.06 ASP 21 -0.28 SER 57

SER 95 0.06 GLU 22 -0.28 ARG 53

SER 95 0.06 ALA 23 -0.24 SER 57

SER 95 0.06 ALA 24 -0.27 SER 57

SER 95 0.07 ARG 25 -0.31 SER 57

SER 95 0.07 LYS 26 -0.27 VAL 56

SER 95 0.06 GLY 27 -0.26 HIS 60

SER 95 0.05 LYS 28 -0.22 SER 57

SER 95 0.05 ARG 29 -0.20 SER 57

SER 95 0.04 LEU 30 -0.20 SER 57

LYS 26 0.04 ALA 31 -0.16 SER 57

LYS 26 0.04 THR 32 -0.17 SER 57

LYS 26 0.05 TYR 33 -0.19 SER 57

LYS 26 0.05 LEU 34 -0.16 ALA 49

GLY 46 0.06 ARG 35 -0.13 SER 57

LYS 26 0.05 GLU 36 -0.15 ALA 49

LYS 26 0.06 LEU 37 -0.16 ALA 49

GLY 46 0.08 LEU 38 -0.13 GLY 46

GLY 46 0.08 GLU 39 -0.11 ALA 49

GLY 46 0.08 SER 40 -0.11 ALA 49

GLY 46 0.11 GLU 41 -0.10 ASN 238

GLY 46 0.09 ASN 42 -0.10 ASN 238

LYS 26 0.08 ASP 43 -0.15 GLU 47

LYS 26 0.08 LEU 44 -0.10 ASN 238

LYS 26 0.09 GLN 45 -0.10 ASN 238

LYS 26 0.08 GLY 46 -0.11 ASN 238

ARG 25 0.09 GLU 47 -0.15 ASP 43

LYS 26 0.12 LEU 48 -0.11 ASN 238

LYS 26 0.14 ALA 49 -0.11 ASN 238

ARG 25 0.13 ALA 50 -0.15 GLU 14

ARG 25 0.13 LEU 51 -0.15 ARG 25

ARG 25 0.16 ARG 52 -0.13 LEU 18

ARG 25 0.17 ARG 53 -0.16 LEU 18

ARG 25 0.15 GLU 54 -0.19 GLU 14

ARG 25 0.17 VAL 55 -0.16 GLU 14

ARG 25 0.21 VAL 56 -0.17 ASP 21

ARG 25 0.19 SER 57 -0.21 LEU 18

ARG 25 0.18 LEU 58 -0.20 GLU 14

ARG 25 0.21 HIS 59 -0.19 ASP 21

ARG 25 0.23 HIS 60 -0.21 ASP 21

ARG 25 0.20 VAL 61 -0.24 ASP 21

ARG 25 0.20 ILE 62 -0.21 ASP 21

ARG 25 0.23 GLU 63 -0.21 ASP 21

ARG 25 0.23 ASP 64 -0.24 ASP 21

ARG 25 0.21 LEU 65 -0.24 ASP 21

ARG 25 0.23 ALA 66 -0.21 ASP 21

ARG 25 0.24 ASP 67 -0.23 ARG 25

ARG 25 0.22 THR 68 -0.25 ARG 25

ARG 25 0.20 GLY 69 -0.24 ASP 21

ARG 25 0.22 LEU 70 -0.22 ARG 25

ARG 25 0.22 ARG 71 -0.24 ARG 25

ARG 25 0.19 SER 72 -0.25 ASP 21

ARG 25 0.20 ASP 73 -0.24 ARG 25

ARG 25 0.20 GLN 74 -0.26 ARG 25

ARG 25 0.19 SER 75 -0.25 ARG 25

ARG 25 0.18 GLY 76 -0.26 ASP 21

ARG 25 0.18 PRO 77 -0.26 ALA 24

ARG 25 0.17 GLY 78 -0.23 ALA 24

ARG 25 0.17 GLN 79 -0.23 ALA 24

ARG 25 0.17 ASN 80 -0.25 ALA 24

ARG 25 0.16 ALA 81 -0.23 ALA 24

ARG 25 0.17 VAL 82 -0.22 ALA 24

ARG 25 0.17 GLN 83 -0.22 ALA 24

ARG 25 0.17 ILE 84 -0.22 ALA 24

ARG 25 0.16 GLU 85 -0.21 ALA 24

ARG 25 0.16 THR 86 -0.20 ALA 24

ARG 25 0.16 LEU 87 -0.21 ALA 24

ARG 25 0.15 LEU 88 -0.20 ALA 24

ARG 25 0.15 LEU 89 -0.19 ALA 24

ARG 25 0.15 LEU 90 -0.19 ALA 24

ARG 25 0.15 ARG 91 -0.18 ALA 24

ARG 25 0.15 ALA 92 -0.17 ALA 24

ARG 25 0.14 ILE 93 -0.17 ALA 24

ARG 25 0.13 ALA 94 -0.17 ALA 24

ARG 25 0.13 GLY 95 -0.16 ALA 24

ARG 25 0.14 PRO 96 -0.16 ALA 24

GLU 99 0.13 GLU 97 -0.16 ALA 24

GLU 99 0.13 ARG 98 -0.17 ALA 24

ARG 25 0.14 MET 99 -0.17 ALA 24

GLU 99 0.14 LYS 100 -0.17 ALA 24

GLU 99 0.14 PRO 101 -0.18 ALA 24

ARG 25 0.14 VAL 102 -0.19 ALA 24

GLU 99 0.15 LYS 103 -0.19 ALA 24

GLU 99 0.15 GLY 104 -0.18 ALA 24

GLU 99 0.15 GLU 105 -0.20 ALA 24

ARG 25 0.16 LEU 106 -0.21 ALA 24

GLU 99 0.17 LYS 107 -0.20 ALA 24

GLU 99 0.16 ARG 108 -0.21 ALA 24

GLU 99 0.16 LEU 109 -0.22 GLY 27

GLU 99 0.18 GLY 110 -0.22 GLY 27

ARG 25 0.17 ILE 111 -0.23 ALA 24

ARG 25 0.17 GLU 112 -0.22 ALA 24

ARG 25 0.16 VAL 113 -0.21 ALA 24

PRO 77 0.18 TRP 114 -0.22 ALA 24

ARG 25 0.17 THR 115 -0.20 ALA 24

ARG 25 0.17 PRO 116 -0.19 ALA 24

ARG 25 0.18 GLU 117 -0.19 ALA 24

PRO 77 0.24 GLY 118 -0.20 ALA 24

GLU 99 0.19 LYS 119 -0.17 ALA 24

GLU 99 0.18 GLU 120 -0.16 ALA 24

ASP 98 0.19 ASP 121 -0.14 ALA 24

ASP 121 0.08 ASN 1 -0.19 ASP 121

ASP 121 0.08 SER 2 -0.18 ASP 121

ASP 121 0.09 VAL 3 -0.18 ASP 121

ASP 121 0.08 GLY 4 -0.18 ASP 121

ASP 121 0.09 GLN 5 -0.17 ASP 121

ASP 121 0.09 GLY 6 -0.17 ASP 121

ASP 121 0.09 GLU 7 -0.17 ASP 121

ASP 121 0.10 PHE 8 -0.16 GLU 97

ASP 121 0.10 GLY 9 -0.14 GLU 97

ASP 121 0.11 GLY 10 -0.14 GLU 97

ASP 121 0.11 ALA 11 -0.14 ASP 121

ASP 121 0.11 PRO 12 -0.16 ASP 121

ASP 121 0.11 PHE 13 -0.17 ASP 121

ASP 121 0.10 LYS 14 -0.18 ASP 121

ASP 121 0.10 ARG 15 -0.19 ASP 121

ASP 121 0.10 PHE 16 -0.19 GLU 97

ASP 121 0.11 LEU 17 -0.19 GLU 97

ASP 121 0.11 ARG 18 -0.20 GLU 97

ASP 121 0.11 GLY 19 -0.19 GLU 97

ASP 121 0.10 THR 20 -0.19 GLU 97

ASP 121 0.10 ARG 21 -0.19 GLU 97

ASP 121 0.09 ILE 22 -0.18 GLU 97

ASP 121 0.08 VAL 23 -0.18 ASP 121

GLU 97 0.08 SER 24 -0.18 ASP 121

GLU 97 0.08 GLY 25 -0.19 ASP 121

GLU 97 0.07 GLY 26 -0.20 ASP 121

GLU 97 0.07 LYS 27 -0.21 ASP 121

GLU 97 0.08 LEU 28 -0.20 ASP 121

GLU 97 0.07 LYS 29 -0.22 ASP 121

GLU 97 0.07 ARG 30 -0.22 ASP 121

GLU 97 0.08 MET 31 -0.22 ASP 121

GLU 97 0.08 THR 32 -0.23 ASP 121

GLU 97 0.08 ARG 33 -0.25 ASP 121

GLU 97 0.08 GLU 34 -0.27 ASP 121

GLU 97 0.07 LYS 35 -0.29 ASP 121

GLU 97 0.07 ALA 36 -0.30 ASP 121

GLU 97 0.07 LYS 37 -0.29 ASP 121

GLU 97 0.07 GLN 38 -0.27 ASP 121

GLU 97 0.07 VAL 39 -0.25 ASP 121

GLU 97 0.07 THR 40 -0.23 ASP 121

GLU 97 0.07 VAL 41 -0.21 ASP 121

GLU 97 0.07 ALA 42 -0.19 ASP 121

GLU 97 0.07 GLY 43 -0.21 ASP 121

GLU 97 0.07 VAL 44 -0.21 ASP 121

GLU 97 0.07 PRO 45 -0.23 ASP 121

GLU 97 0.08 MET 46 -0.23 ASP 121

GLU 97 0.08 PRO 47 -0.24 ASP 121

GLU 97 0.08 ARG 48 -0.26 GLU 97

GLU 97 0.09 ASP 49 -0.27 GLU 97

GLU 97 0.09 ALA 50 -0.25 GLU 97

GLU 97 0.09 GLU 51 -0.25 GLU 97

GLU 97 0.09 PRO 52 -0.27 GLU 97

GLU 97 0.11 ARG 53 -0.25 GLU 97

GLU 97 0.10 HIS 54 -0.22 GLU 97

GLU 97 0.09 LEU 55 -0.20 GLU 97

GLU 97 0.09 LEU 56 -0.18 GLU 97

GLU 97 0.09 VAL 57 -0.17 GLU 97

ASP 121 0.09 ASN 58 -0.15 GLU 97

ASP 121 0.08 GLY 59 -0.14 GLU 97

LYS 66 0.09 ALA 60 -0.12 GLU 97

LYS 66 0.09 THR 61 -0.12 THR 66

THR 67 0.08 GLY 62 -0.13 THR 66

THR 67 0.07 THR 63 -0.13 ASP 121

GLU 97 0.06 GLY 64 -0.14 ASP 121

GLU 97 0.07 LYS 65 -0.15 ASP 121

GLU 97 0.06 SER 66 -0.16 THR 66

GLU 97 0.06 VAL 67 -0.17 ASP 121

GLU 97 0.07 LEU 68 -0.18 ASP 121

GLU 97 0.07 LEU 69 -0.18 ASP 121

GLU 97 0.06 ARG 70 -0.19 ASP 121

GLU 97 0.06 GLU 71 -0.21 ASP 121

GLU 97 0.07 LEU 72 -0.22 ASP 121

GLU 97 0.06 ALA 73 -0.22 ASP 121

GLU 97 0.06 TYR 74 -0.23 ASP 121

GLU 97 0.06 THR 75 -0.25 ASP 121

GLU 97 0.07 GLY 76 -0.26 ASP 121

GLU 97 0.06 LEU 77 -0.28 ASP 121

GLU 97 0.06 LEU 78 -0.29 ASP 121

GLU 97 0.06 ARG 79 -0.31 ASP 121

GLU 97 0.06 GLY 80 -0.33 ASP 121

GLU 97 0.07 ASP 81 -0.31 ASP 121

GLU 97 0.07 ARG 82 -0.28 ASP 121

GLU 97 0.07 MET 83 -0.24 ASP 121

GLU 97 0.07 VAL 84 -0.21 ASP 121

GLU 97 0.06 ILE 85 -0.19 ASP 121

LYS 66 0.07 VAL 86 -0.17 THR 66

THR 67 0.06 ASP 87 -0.18 THR 66

LYS 66 0.07 PRO 88 -0.17 THR 66

THR 67 0.07 ASN 89 -0.19 THR 66

THR 67 0.06 GLY 90 -0.20 THR 66

THR 67 0.05 ASP 91 -0.19 THR 66

GLU 97 0.05 MET 92 -0.19 THR 66

GLU 97 0.04 LEU 93 -0.21 THR 66

GLU 97 0.04 SER 94 -0.22 THR 66

GLU 97 0.05 LYS 95 -0.21 THR 66

GLU 97 0.05 PHE 96 -0.21 ASP 121

GLU 97 0.05 GLY 97 -0.22 THR 66

GLU 97 0.04 ARG 98 -0.24 ASP 121

LYS 100 0.05 ASP 99 -0.25 THR 66

ASP 99 0.05 LYS 100 -0.28 ASP 121

GLU 97 0.05 ASP 101 -0.25 ASP 121

GLU 97 0.04 ILE 102 -0.21 GLY 27

THR 67 0.05 ILE 103 -0.21 THR 66

LYS 66 0.07 LEU 104 -0.20 THR 66

LYS 66 0.08 ASN 105 -0.20 THR 66

GLU 99 0.09 PRO 106 -0.21 THR 66

LYS 66 0.08 TYR 107 -0.22 THR 66

LYS 66 0.07 ASP 108 -0.23 THR 66

THR 67 0.06 GLN 109 -0.25 THR 66

THR 67 0.05 ARG 110 -0.24 THR 66

LYS 66 0.06 THR 111 -0.23 THR 66

LYS 66 0.06 LYS 112 -0.22 GLY 27

LYS 66 0.07 GLY 113 -0.22 GLY 27

GLU 99 0.08 TRP 114 -0.20 GLY 27

GLU 99 0.10 SER 115 -0.19 GLY 27

GLU 99 0.10 PHE 116 -0.17 GLY 27

GLU 99 0.11 PHE 117 -0.19 GLY 27

GLU 99 0.09 ASN 118 -0.20 ARG 25

GLU 99 0.09 GLU 119 -0.18 GLY 27

GLU 99 0.10 ILE 120 -0.18 ALA 24

GLU 99 0.09 ARG 121 -0.27 GLU 97

GLU 99 0.10 ASN 122 -0.20 GLY 95

GLU 99 0.11 ASP 123 -0.16 ALA 24

GLU 97 0.13 TYR 124 -0.16 GLY 95

GLU 99 0.11 ASP 125 -0.16 PRO 96

GLU 99 0.12 TRP 126 -0.15 ALA 24

GLU 97 0.13 GLN 127 -0.13 ALA 24

GLU 97 0.12 ARG 128 -0.16 PRO 96

GLU 99 0.11 TYR 129 -0.15 PRO 96

GLU 99 0.12 ALA 130 -0.13 ALA 24

GLU 99 0.12 LEU 131 -0.13 PRO 96

GLU 99 0.11 SER 132 -0.14 PRO 96

GLU 99 0.12 VAL 133 -0.14 THR 66

GLU 99 0.13 VAL 134 -0.12 THR 66

GLU 99 0.12 PRO 135 -0.12 THR 66

ALA 146 0.14 ARG 136 -0.13 GLU 97

ALA 146 0.15 GLY 137 -0.11 GLU 97

VAL 323 0.21 LYS 138 -0.12 GLU 97

GLY 325 0.27 THR 139 -0.11 GLU 97

GLY 325 0.22 ASP 140 -0.11 GLU 97

GLY 325 0.17 GLU 141 -0.10 GLU 97

TRP 145 0.18 ALA 142 -0.10 GLU 97

GLY 325 0.15 GLU 143 -0.11 GLU 97

ASP 121 0.15 GLU 144 -0.10 GLU 97

ALA 142 0.18 TRP 145 -0.09 GLU 97

GLY 137 0.15 ALA 146 -0.10 THR 66

GLU 99 0.14 SER 147 -0.11 GLU 97

GLU 99 0.15 TYR 148 -0.10 THR 66

GLU 99 0.15 GLY 149 -0.11 THR 66

GLU 99 0.14 ARG 150 -0.12 ALA 24

GLU 99 0.14 LEU 151 -0.12 ALA 24

GLU 99 0.15 LEU 152 -0.12 ALA 24

GLU 99 0.14 LEU 153 -0.14 ALA 24

GLU 99 0.13 ARG 154 -0.14 ALA 24

GLU 99 0.14 GLU 155 -0.15 ALA 24

GLU 99 0.15 THR 156 -0.15 ALA 24

GLU 99 0.14 ALA 157 -0.16 ALA 24

GLU 99 0.13 LYS 158 -0.17 ALA 24

GLU 99 0.14 LYS 159 -0.17 ALA 24

GLU 99 0.14 LEU 160 -0.18 ALA 24

GLU 99 0.13 ALA 161 -0.19 ALA 24

ASP 21 0.13 LEU 162 -0.20 ALA 24

GLU 99 0.14 ILE 163 -0.20 ALA 24

GLU 99 0.13 GLY 164 -0.21 ARG 25

GLU 99 0.14 THR 165 -0.21 GLY 27

GLU 99 0.13 PRO 166 -0.20 ASP 227

GLU 99 0.13 SER 167 -0.21 GLY 226

GLU 99 0.14 MET 168 -0.17 GLY 27

GLU 99 0.15 ARG 169 -0.18 THR 66

GLU 99 0.15 GLU 170 -0.18 GLY 27

GLU 99 0.15 LEU 171 -0.17 ALA 24

GLU 99 0.16 PHE 172 -0.16 THR 66

GLU 99 0.17 HIS 173 -0.16 THR 66

GLU 99 0.17 TRP 174 -0.15 ALA 24

GLU 99 0.16 THR 175 -0.14 THR 66

GLU 99 0.17 THR 176 -0.14 THR 66

GLU 99 0.18 ILE 177 -0.14 THR 66

GLU 99 0.19 ALA 178 -0.14 THR 66

GLU 99 0.20 THR 179 -0.13 THR 66

ASP 98 0.19 PHE 180 -0.11 THR 66

ASP 98 0.19 ASP 181 -0.12 ALA 24

GLU 99 0.19 ASP 182 -0.14 ALA 24

GLU 99 0.18 LEU 183 -0.14 ALA 24

GLU 99 0.18 ARG 184 -0.13 ALA 24

GLU 99 0.18 GLY 185 -0.15 ALA 24

GLU 99 0.17 PHE 186 -0.16 ALA 24

GLU 99 0.16 LEU 187 -0.15 ALA 24

GLU 99 0.16 GLU 188 -0.15 ALA 24

GLU 99 0.15 GLY 189 -0.15 ALA 24

GLU 99 0.15 THR 190 -0.14 ALA 24

PRO 101 0.14 LEU 191 -0.13 ALA 24

GLU 99 0.15 ALA 192 -0.12 ALA 24

GLU 99 0.16 GLU 193 -0.12 ALA 24

GLU 99 0.16 SER 194 -0.10 ALA 24

GLU 99 0.16 LEU 195 -0.10 ALA 24

GLU 99 0.17 PHE 196 -0.09 ASP 5

ASP 98 0.17 ALA 197 -0.09 ASP 5

ASP 98 0.18 GLY 198 -0.08 ASP 5

ASP 98 0.18 SER 199 -0.06 ASP 5

ASP 98 0.19 ASN 200 -0.06 ASP 5

GLY 374 0.17 GLU 201 -0.07 GLY 95

ASP 98 0.17 ALA 202 -0.08 ASP 5

ASP 98 0.18 SER 203 -0.07 LYS 65

ASP 98 0.18 LYS 204 -0.07 LYS 65

GLU 99 0.16 ALA 205 -0.08 THR 66

GLU 99 0.17 LEU 206 -0.09 THR 66

GLU 99 0.18 THR 207 -0.09 THR 66

GLU 99 0.17 SER 208 -0.09 THR 66

GLU 99 0.16 ALA 209 -0.10 THR 66

GLU 99 0.17 ARG 210 -0.11 THR 66

GLU 99 0.17 PHE 211 -0.11 THR 66

GLU 99 0.15 VAL 212 -0.11 THR 66

GLU 99 0.15 LEU 213 -0.13 THR 66

GLU 99 0.16 SER 214 -0.13 THR 66

GLU 99 0.15 ASP 215 -0.13 THR 66

GLU 99 0.14 LYS 216 -0.14 THR 66

GLU 99 0.14 LEU 217 -0.15 THR 66

GLU 99 0.14 PRO 218 -0.16 THR 66

GLU 99 0.13 GLU 219 -0.17 THR 66

GLU 99 0.12 HIS 220 -0.17 THR 66

GLU 99 0.13 VAL 221 -0.18 THR 66

GLU 99 0.12 THR 222 -0.20 THR 66

GLU 99 0.10 MET 223 -0.20 THR 66

GLU 99 0.09 PRO 224 -0.22 THR 66

GLU 99 0.09 ASP 225 -0.22 ASP 121

LYS 66 0.07 GLY 226 -0.34 ASP 121

LYS 66 0.06 ASP 227 -0.29 GLU 120

LYS 66 0.06 PHE 228 -0.26 GLY 104

LYS 66 0.06 SER 229 -0.24 GLY 104

GLU 97 0.06 ILE 230 -0.20 GLY 104

GLU 97 0.07 ARG 231 -0.25 PRO 96

GLU 97 0.06 SER 232 -0.31 PRO 101

GLU 97 0.06 TRP 233 -0.27 ASP 121

GLU 97 0.07 LEU 234 -0.27 PRO 96

GLU 97 0.08 GLU 235 -0.35 PRO 96

GLU 97 0.06 ASP 236 -0.37 ASP 121

GLU 97 0.07 PRO 237 -0.37 ASP 121

GLU 97 0.06 ASN 238 -0.40 ASP 121

GLU 97 0.05 GLY 239 -0.34 ASP 121

GLU 97 0.06 GLY 240 -0.31 ASP 121

GLU 97 0.06 ASN 241 -0.26 ASP 121

GLU 97 0.05 LEU 242 -0.21 ASP 121

THR 67 0.05 PHE 243 -0.19 THR 66

LYS 66 0.07 ILE 244 -0.18 THR 66

LYS 66 0.07 THR 245 -0.19 THR 66

LYS 66 0.08 TRP 246 -0.18 THR 66

LYS 66 0.09 ARG 247 -0.18 THR 66

LYS 66 0.09 GLU 248 -0.17 THR 66

GLU 99 0.10 ASP 249 -0.17 THR 66

GLU 99 0.11 MET 250 -0.17 THR 66

GLU 99 0.11 GLY 251 -0.16 THR 66

GLU 99 0.12 PRO 252 -0.14 THR 66

GLU 99 0.13 ALA 253 -0.15 THR 66

GLU 99 0.11 LEU 254 -0.16 THR 66

GLU 99 0.11 ARG 255 -0.14 THR 66

GLU 99 0.12 PRO 256 -0.14 THR 66

GLU 99 0.11 LEU 257 -0.16 THR 66

GLU 99 0.10 ILE 258 -0.16 THR 66

GLU 99 0.10 SER 259 -0.14 THR 66

GLU 99 0.10 ALA 260 -0.15 THR 66

GLU 99 0.09 TRP 261 -0.16 THR 66

GLU 99 0.08 VAL 262 -0.16 PRO 96

GLU 97 0.10 ASP 263 -0.17 PRO 96

GLU 97 0.08 VAL 264 -0.18 PRO 96

GLU 97 0.08 VAL 265 -0.21 PRO 96

GLU 97 0.10 CYS 266 -0.21 PRO 96

GLU 97 0.11 THR 267 -0.22 PRO 96

GLU 97 0.09 SER 268 -0.26 PRO 96

GLU 97 0.09 ILE 269 -0.28 PRO 96

GLU 97 0.11 LEU 270 -0.28 GLU 97

GLU 97 0.10 SER 271 -0.32 PRO 96

GLU 97 0.09 LEU 272 -0.37 PRO 96

GLU 97 0.10 PRO 273 -0.43 GLU 97

GLU 97 0.11 GLU 274 -0.40 GLU 97

GLU 97 0.09 GLU 275 -0.40 GLU 97

GLU 97 0.10 PRO 276 -0.36 GLU 97

GLU 97 0.09 LYS 277 -0.35 GLU 97

GLU 97 0.08 ARG 278 -0.34 GLU 97

GLU 97 0.08 ARG 279 -0.29 ASP 121

GLU 97 0.08 LEU 280 -0.27 ASP 121

GLU 97 0.08 TRP 281 -0.24 ASP 121

GLU 97 0.08 LEU 282 -0.21 PRO 96

GLU 97 0.07 PHE 283 -0.19 ASP 121

GLU 97 0.08 ILE 284 -0.16 GLU 97

LYS 66 0.07 ASP 285 -0.15 THR 66

LYS 66 0.08 GLU 286 -0.14 GLU 97

GLU 97 0.09 LEU 287 -0.15 GLU 97

GLU 99 0.10 ALA 288 -0.13 GLU 97

GLU 99 0.10 SER 289 -0.12 THR 66

GLU 99 0.10 LEU 290 -0.13 THR 66

GLU 99 0.12 GLU 291 -0.12 GLU 97

GLU 99 0.12 LYS 292 -0.13 GLU 97

GLU 97 0.11 LEU 293 -0.15 GLU 97

GLU 97 0.12 ALA 294 -0.16 GLU 97

GLU 97 0.12 SER 295 -0.19 GLU 97

GLU 97 0.11 LEU 296 -0.19 GLU 97

GLU 97 0.12 ALA 297 -0.20 GLU 97

GLU 97 0.14 ASP 298 -0.23 GLU 97

GLU 97 0.12 ALA 299 -0.24 GLU 97

GLU 97 0.12 LEU 300 -0.23 GLU 97

GLU 97 0.13 THR 301 -0.24 GLU 97

GLU 97 0.13 LYS 302 -0.27 GLU 97

GLU 97 0.11 GLY 303 -0.28 GLU 97

GLU 97 0.11 ARG 304 -0.29 GLU 97

GLU 97 0.11 LYS 305 -0.33 GLU 97

GLU 97 0.10 ALA 306 -0.34 GLU 97

GLU 97 0.09 GLY 307 -0.32 GLU 97

GLU 97 0.09 LEU 308 -0.28 GLU 97

GLU 97 0.09 ARG 309 -0.25 GLU 97

GLU 97 0.09 VAL 310 -0.22 GLU 97

GLU 97 0.08 VAL 311 -0.19 GLU 97

GLU 97 0.09 ALA 312 -0.17 GLU 97

GLU 97 0.08 GLY 313 -0.15 GLU 97

ASP 121 0.09 LEU 314 -0.14 GLU 97

LYS 66 0.09 GLN 315 -0.13 GLU 97

GLU 99 0.10 SER 316 -0.13 GLU 97

ASP 121 0.11 THR 317 -0.14 GLU 97

THR 139 0.12 SER 318 -0.13 GLU 97

GLU 99 0.12 GLN 319 -0.12 GLU 97

LYS 138 0.12 LEU 320 -0.14 GLU 97

THR 139 0.16 ASP 321 -0.13 GLU 97

LYS 138 0.18 ASP 322 -0.11 GLU 97

LYS 138 0.21 VAL 323 -0.12 GLU 97

LYS 138 0.19 TYR 324 -0.14 GLU 97

THR 139 0.27 GLY 325 -0.13 GLU 97

THR 139 0.19 VAL 326 -0.14 GLU 97

ASP 140 0.19 LYS 327 -0.16 GLU 97

ASP 140 0.19 GLU 328 -0.16 GLU 97

THR 139 0.16 ALA 329 -0.16 GLU 97

ASP 140 0.14 GLN 330 -0.17 GLU 97

ASP 140 0.14 THR 331 -0.19 GLU 97

GLU 97 0.12 LEU 332 -0.19 GLU 97

GLU 97 0.11 ARG 333 -0.18 GLU 97

GLU 97 0.13 ALA 334 -0.19 GLU 97

GLU 97 0.12 SER 335 -0.21 GLU 97

GLU 97 0.11 PHE 336 -0.21 GLU 97

GLU 97 0.11 ARG 337 -0.21 GLU 97

GLU 97 0.10 SER 338 -0.21 GLU 97

GLU 97 0.09 LEU 339 -0.19 GLU 97

GLU 97 0.09 VAL 340 -0.17 GLU 97

ASP 121 0.09 VAL 341 -0.16 GLU 97

ASP 121 0.08 LEU 342 -0.15 GLU 97

ASP 121 0.08 GLY 343 -0.13 GLU 97

ASP 121 0.09 GLY 344 -0.13 GLU 97

LYS 66 0.10 SER 345 -0.11 GLU 97

LYS 66 0.10 ARG 346 -0.11 GLU 97

LYS 66 0.11 THR 347 -0.10 GLU 97

THR 373 0.11 ASP 348 -0.11 GLU 97

THR 373 0.12 PRO 349 -0.12 GLU 97

THR 373 0.12 LYS 350 -0.13 GLU 97

ASP 121 0.11 THR 351 -0.14 GLU 97

ASP 121 0.11 ASN 352 -0.13 GLU 97

ASP 121 0.12 GLU 353 -0.14 GLU 97

THR 139 0.13 ASP 354 -0.15 GLU 97

ASP 121 0.11 MET 355 -0.15 GLU 97

ASP 121 0.11 SER 356 -0.15 GLU 97

ASP 140 0.13 LEU 357 -0.16 GLU 97

ASP 140 0.12 SER 358 -0.17 GLU 97

ASP 121 0.11 LEU 359 -0.17 GLU 97

ASP 121 0.12 GLY 360 -0.17 GLU 97

ASP 121 0.12 GLU 361 -0.16 GLU 97

ASP 121 0.12 HIS 362 -0.17 GLU 97

ASP 121 0.13 GLU 363 -0.17 GLU 97

ASP 121 0.12 VAL 364 -0.17 GLU 97

ASP 121 0.12 GLU 365 -0.17 ASP 121

ASP 121 0.12 ARG 366 -0.16 ASP 121

ASP 121 0.13 ASP 367 -0.16 ASP 121

ASP 121 0.14 ARG 368 -0.14 ASP 121

ASP 121 0.14 TYR 369 -0.14 ASP 121

ASP 121 0.15 SER 370 -0.13 ASP 121

ASP 121 0.16 LYS 371 -0.12 ASP 121

ASP 121 0.17 ASN 372 -0.11 ASP 121

ASN 200 0.17 THR 373 -0.10 ASP 121

ASP 121 0.18 GLY 374 -0.10 ASP 121

ASP 121 0.17 LYS 375 -0.11 ASP 121

ASP 121 0.16 HIS 376 -0.13 ASP 121

ASP 121 0.15 HIS 377 -0.13 ASP 121

ASP 121 0.15 SER 378 -0.14 ASP 121

ASP 121 0.14 THR 379 -0.14 ASP 121

ASP 121 0.14 GLY 380 -0.15 ASP 121

ASP 121 0.13 ARG 381 -0.16 ASP 121

ASP 121 0.14 ALA 382 -0.16 ASP 121

ASP 121 0.13 LEU 383 -0.16 ASP 121

ASP 121 0.14 GLU 384 -0.15 ASP 121

ASP 121 0.14 ARG 385 -0.16 ASP 121

ASP 121 0.14 VAL 386 -0.15 GLU 97

ASP 121 0.14 ARG 387 -0.15 GLU 97

ASP 121 0.13 GLU 388 -0.15 GLU 97

ASP 121 0.12 ARG 389 -0.15 GLU 97

ASP 121 0.11 VAL 390 -0.16 GLU 97

ASP 121 0.11 VAL 391 -0.15 GLU 97

ASP 121 0.11 MET 392 -0.14 GLU 97

ASP 121 0.11 PRO 393 -0.13 GLU 97

ASP 121 0.11 ALA 394 -0.13 GLU 97

ASP 121 0.10 GLU 395 -0.14 GLU 97

ASP 121 0.10 ILE 396 -0.14 GLU 97

ASP 121 0.09 ALA 397 -0.13 GLU 97

ASP 121 0.09 ASN 398 -0.12 GLU 97

ASP 121 0.08 LEU 399 -0.13 GLU 97

ASP 121 0.07 PRO 400 -0.13 ASP 121

THR 67 0.07 ASP 401 -0.13 ASP 121

GLU 97 0.06 LEU 402 -0.15 ASP 121

GLU 97 0.07 THR 403 -0.15 ASP 121

GLU 97 0.08 ALA 404 -0.16 ASP 121

ASP 121 0.08 TYR 405 -0.17 GLU 97

GLU 97 0.08 VAL 406 -0.18 GLU 97

GLU 97 0.09 GLY 407 -0.19 GLU 97

GLU 97 0.09 PHE 408 -0.21 GLU 97

GLU 97 0.10 ALA 409 -0.22 GLU 97

GLU 97 0.11 GLY 410 -0.23 GLU 97

GLU 97 0.10 ASN 411 -0.22 GLU 97

GLU 97 0.10 ARG 412 -0.21 GLU 97

GLU 97 0.09 PRO 413 -0.20 GLU 97

GLU 97 0.09 ILE 414 -0.18 GLU 97

GLU 97 0.08 ALA 415 -0.18 ASP 121

ASP 121 0.08 LYS 416 -0.17 ASP 121

GLU 97 0.07 VAL 417 -0.17 ASP 121

GLU 97 0.07 PRO 418 -0.17 ASP 121

GLU 97 0.06 LEU 419 -0.17 ASP 121

GLU 97 0.06 GLU 420 -0.18 ASP 121

GLU 97 0.05 ILE 421 -0.17 THR 66

GLU 97 0.05 LYS 422 -0.18 ASP 121

GLU 97 0.05 GLN 423 -0.20 THR 66

GLU 97 0.05 PHE 424 -0.20 THR 66

GLU 97 0.04 ALA 425 -0.22 THR 66

GLU 97 0.04 ASN 426 -0.22 THR 66

GLU 97 0.04 ARG 427 -0.23 THR 66

GLU 97 0.03 GLN 428 -0.24 THR 66

THR 67 0.04 PRO 429 -0.24 THR 66

THR 67 0.05 ALA 430 -0.22 THR 66

THR 67 0.06 PHE 431 -0.22 THR 66

THR 67 0.06 VAL 432 -0.24 THR 66

LYS 66 0.07 GLU 433 -0.24 THR 66

LYS 66 0.07 GLY 434 -0.25 THR 66

LYS 66 0.08 THR 435 -0.27 THR 66

GLU 99 0.10 ILE 436 -0.25 THR 66

LYS 26 0.04 MET 1 -0.11 ASP 67

LYS 26 0.04 ALA 2 -0.12 ASP 67

LYS 26 0.04 LEU 3 -0.12 SER 57

LYS 26 0.04 GLY 4 -0.15 SER 57

LYS 26 0.04 ASP 5 -0.15 ASP 64

LYS 26 0.04 PRO 6 -0.14 SER 57

LYS 26 0.04 ILE 7 -0.15 SER 57

GLY 46 0.05 GLN 8 -0.14 SER 57

GLY 46 0.06 VAL 9 -0.13 SER 57

GLY 46 0.06 ARG 10 -0.12 SER 57

GLY 46 0.07 LEU 11 -0.11 SER 57

GLY 46 0.08 SER 12 -0.10 ASP 99

GLY 46 0.09 PRO 13 -0.09 ASP 99

GLY 46 0.10 GLU 14 -0.08 ALA 36

GLY 46 0.10 LYS 15 -0.09 GLY 46

GLY 46 0.09 GLN 16 -0.09 GLY 46

GLY 46 0.11 ALA 17 -0.08 GLY 46

GLY 46 0.12 LEU 18 -0.08 GLY 46

GLY 46 0.11 LEU 19 -0.10 GLY 46

GLY 46 0.09 GLU 20 -0.09 GLY 46

GLY 46 0.10 ASP 21 -0.09 GLY 46

GLY 46 0.11 GLU 22 -0.10 GLY 46

GLY 46 0.10 ALA 23 -0.09 GLY 46

GLY 46 0.09 ALA 24 -0.08 GLY 46

GLY 46 0.10 ARG 25 -0.08 GLY 46

GLY 46 0.10 LYS 26 -0.09 GLY 46

GLY 46 0.09 GLY 27 -0.08 GLY 46

GLY 46 0.10 LYS 28 -0.07 ALA 36

GLY 46 0.09 ARG 29 -0.08 ALA 36

GLY 46 0.09 LEU 30 -0.09 GLY 46

GLY 46 0.08 ALA 31 -0.09 GLY 46

GLY 46 0.08 THR 32 -0.09 GLY 46

GLY 46 0.09 TYR 33 -0.10 GLY 46

GLY 46 0.08 LEU 34 -0.12 GLY 46

GLY 46 0.07 ARG 35 -0.12 GLY 46

GLY 46 0.08 GLU 36 -0.12 GLY 46

GLY 46 0.09 LEU 37 -0.12 GLY 46

GLY 46 0.07 LEU 38 -0.15 GLY 46

LYS 26 0.06 GLU 39 -0.16 GLY 46

GLN 45 0.09 SER 40 -0.15 GLY 46

GLN 45 0.07 GLU 41 -0.19 GLY 46

LYS 26 0.06 ASN 42 -0.33 GLY 46

ARG 25 0.06 ASP 43 -0.20 GLY 46

ARG 25 0.07 LEU 44 -0.10 GLU 41

ARG 25 0.06 GLN 45 -0.18 ALA 49

SER 199 0.07 GLY 46 -0.33 ASN 42

ARG 25 0.08 GLU 47 -0.14 ASP 43

ARG 25 0.09 LEU 48 -0.18 GLN 45

ARG 25 0.08 ALA 49 -0.25 GLU 22

ARG 25 0.09 ALA 50 -0.25 GLU 22

ARG 25 0.11 LEU 51 -0.19 GLU 22

ARG 25 0.11 ARG 52 -0.23 ARG 25

ARG 25 0.10 ARG 53 -0.29 ARG 25

ARG 25 0.11 GLU 54 -0.24 ARG 25

ARG 25 0.13 VAL 55 -0.24 ARG 25

ARG 25 0.12 VAL 56 -0.30 ARG 25

ARG 25 0.12 SER 57 -0.31 ARG 25

ARG 25 0.14 LEU 58 -0.26 ARG 25

ARG 25 0.15 HIS 59 -0.26 ARG 25

ARG 25 0.13 HIS 60 -0.31 ARG 25

ARG 25 0.14 VAL 61 -0.27 ARG 25

ARG 25 0.16 ILE 62 -0.24 ARG 25

ARG 25 0.16 GLU 63 -0.26 GLU 14

ARG 25 0.15 ASP 64 -0.29 ARG 25

ARG 25 0.16 LEU 65 -0.24 ARG 25

ARG 25 0.18 ALA 66 -0.26 ASP 21

ARG 25 0.16 ASP 67 -0.29 ASP 21

ARG 25 0.16 THR 68 -0.26 ALA 17

ARG 25 0.18 GLY 69 -0.25 ASP 21

ARG 25 0.18 LEU 70 -0.27 ASP 21

ARG 25 0.16 ARG 71 -0.27 ASP 21

ARG 25 0.17 SER 72 -0.25 ASP 21

ARG 25 0.18 ASP 73 -0.25 ASP 21

ARG 25 0.17 GLN 74 -0.25 ASP 21

ARG 25 0.17 SER 75 -0.23 ASP 21

ARG 25 0.16 GLY 76 -0.22 ASP 21

ARG 25 0.15 PRO 77 -0.22 ALA 17

ARG 25 0.15 GLY 78 -0.20 ALA 17

ARG 25 0.16 GLN 79 -0.21 ASP 21

ARG 25 0.15 ASN 80 -0.22 ASP 21

ARG 25 0.15 ALA 81 -0.21 ASP 21

ARG 25 0.15 VAL 82 -0.20 ASP 21

ARG 25 0.16 GLN 83 -0.21 ASP 21

ARG 25 0.15 ILE 84 -0.20 ASP 21

ARG 25 0.15 GLU 85 -0.19 ASP 21

ARG 25 0.15 THR 86 -0.19 ALA 24

ARG 25 0.15 LEU 87 -0.20 ALA 24

ARG 25 0.14 LEU 88 -0.19 ALA 24

ARG 25 0.14 LEU 89 -0.18 ALA 24

ARG 25 0.14 LEU 90 -0.18 ALA 24

ARG 25 0.14 ARG 91 -0.18 ALA 24

ARG 25 0.14 ALA 92 -0.17 ALA 24

ARG 25 0.13 ILE 93 -0.17 ALA 24

ARG 25 0.14 ALA 94 -0.17 ALA 24

ARG 25 0.13 GLY 95 -0.16 ALA 24

GLY 374 0.14 PRO 96 -0.16 ALA 24

GLY 374 0.14 GLU 97 -0.15 ALA 24

ARG 25 0.14 ARG 98 -0.16 ALA 24

ARG 25 0.14 MET 99 -0.17 ALA 24

GLY 374 0.15 LYS 100 -0.16 ALA 24

ARG 25 0.15 PRO 101 -0.17 ALA 24

ARG 25 0.15 VAL 102 -0.18 ALA 24

ARG 25 0.15 LYS 103 -0.18 ALA 24

ALA 197 0.16 GLY 104 -0.17 ALA 24

ARG 25 0.16 GLU 105 -0.18 ALA 24

ARG 25 0.16 LEU 106 -0.19 ALA 24

ARG 25 0.16 LYS 107 -0.18 ALA 24

ALA 197 0.17 ARG 108 -0.18 ALA 24

ARG 25 0.17 LEU 109 -0.20 ALA 24

ARG 25 0.17 GLY 110 -0.21 ALA 24

ARG 25 0.17 ILE 111 -0.22 ALA 24

ARG 25 0.16 GLU 112 -0.21 ALA 24

ARG 25 0.16 VAL 113 -0.20 ALA 24

ARG 25 0.16 TRP 114 -0.21 ALA 24

ARG 25 0.15 THR 115 -0.19 ALA 24

ARG 25 0.14 PRO 116 -0.19 ASP 5

GLY 374 0.15 GLU 117 -0.20 ASP 5

ARG 25 0.15 GLY 118 -0.20 ASP 5

GLY 374 0.15 LYS 119 -0.19 ASP 5

GLY 374 0.16 GLU 120 -0.18 ASP 5

GLY 374 0.18 ASP 121 -0.18 ASP 5

LYS 119 0.07 MET 1 -0.07 LYS 35

LYS 119 0.09 ALA 2 -0.06 LYS 35

LYS 119 0.09 LEU 3 -0.06 LYS 35

GLU 117 0.09 GLY 4 -0.07 GLY 46

GLU 117 0.11 ASP 5 -0.06 LYS 35

GLU 117 0.12 PRO 6 -0.06 LYS 35

GLU 117 0.12 ILE 7 -0.06 LYS 35

GLU 117 0.14 GLN 8 -0.06 LYS 35

GLU 117 0.14 VAL 9 -0.06 LYS 35

GLY 110 0.15 ARG 10 -0.06 LYS 35

SER 57 0.16 LEU 11 -0.07 LYS 35

SER 57 0.18 SER 12 -0.07 LYS 35

SER 57 0.20 PRO 13 -0.06 LYS 35

SER 57 0.23 GLU 14 -0.07 LYS 35

SER 57 0.22 LYS 15 -0.07 LYS 35

SER 57 0.21 GLN 16 -0.07 LYS 35

SER 57 0.24 ALA 17 -0.06 LYS 35

SER 57 0.27 LEU 18 -0.07 LYS 35

SER 57 0.23 LEU 19 -0.07 LYS 35

HIS 60 0.23 GLU 20 -0.06 LYS 35

HIS 60 0.27 ASP 21 -0.07 LYS 35

VAL 56 0.27 GLU 22 -0.07 LYS 35

HIS 60 0.22 ALA 23 -0.07 LYS 35

HIS 60 0.25 ALA 24 -0.06 LYS 35

HIS 60 0.28 ARG 25 -0.07 LYS 35

VAL 56 0.23 LYS 26 -0.07 LYS 35

HIS 60 0.22 GLY 27 -0.06 LYS 35

HIS 60 0.19 LYS 28 -0.06 LYS 35

ASP 64 0.18 ARG 29 -0.06 LYS 35

HIS 60 0.18 LEU 30 -0.06 LYS 35

ASP 64 0.15 ALA 31 -0.06 LYS 35

HIS 60 0.14 THR 32 -0.07 LYS 35

VAL 56 0.16 TYR 33 -0.07 LYS 35

VAL 56 0.15 LEU 34 -0.07 LYS 35

VAL 56 0.12 ARG 35 -0.07 LYS 35

VAL 56 0.12 GLU 36 -0.08 LYS 35

ALA 49 0.13 LEU 37 -0.08 LYS 35

ALA 49 0.11 LEU 38 -0.08 LYS 35

VAL 56 0.09 GLU 39 -0.08 LYS 35

VAL 56 0.09 SER 40 -0.08 LYS 35

GLY 46 0.09 GLU 41 -0.10 LEU 44

LYS 28 0.09 ASN 42 -0.09 LYS 35

GLU 47 0.14 ASP 43 -0.09 LYS 35

GLU 47 0.09 LEU 44 -0.09 LYS 35

SER 40 0.09 GLN 45 -0.10 ALA 36

ASP 43 0.08 GLY 46 -0.09 ALA 36

ASP 43 0.14 GLU 47 -0.10 ALA 36

ARG 25 0.09 LEU 48 -0.10 ASN 238

ARG 25 0.09 ALA 49 -0.09 ASN 238

ARG 25 0.15 ALA 50 -0.10 ALA 36

ARG 25 0.15 LEU 51 -0.11 ARG 25

ARG 25 0.12 ARG 52 -0.14 GLU 22

ARG 25 0.15 ARG 53 -0.13 ARG 25

ARG 25 0.19 GLU 54 -0.13 ARG 25

ARG 25 0.16 VAL 55 -0.17 ARG 25

ARG 25 0.15 VAL 56 -0.18 ARG 25

ARG 25 0.20 SER 57 -0.16 ARG 25

ARG 25 0.20 LEU 58 -0.18 ARG 25

ARG 25 0.16 HIS 59 -0.21 ARG 25

ARG 25 0.18 HIS 60 -0.20 ARG 25

ARG 25 0.21 VAL 61 -0.18 ARG 25

ARG 25 0.18 ILE 62 -0.21 ARG 25

ARG 25 0.16 GLU 63 -0.22 ARG 25

ARG 25 0.19 ASP 64 -0.20 ARG 25

ARG 25 0.20 LEU 65 -0.20 ARG 25

ARG 25 0.17 ALA 66 -0.24 ARG 25

ARG 25 0.17 ASP 67 -0.23 ARG 25

ARG 25 0.19 THR 68 -0.20 ARG 25

ARG 25 0.18 GLY 69 -0.21 ARG 25

ARG 25 0.16 LEU 70 -0.23 ARG 25

ARG 25 0.17 ARG 71 -0.21 ARG 25

ARG 25 0.19 SER 72 -0.20 ASP 21

ARG 25 0.17 ASP 73 -0.22 ASP 21

ARG 25 0.17 GLN 74 -0.21 ALA 17

ARG 25 0.17 SER 75 -0.20 ASP 21

ARG 25 0.18 GLY 76 -0.19 ASP 21

ARG 25 0.17 PRO 77 -0.18 ALA 17

ARG 25 0.18 GLY 78 -0.17 ASP 21

ARG 25 0.17 GLN 79 -0.18 ASP 21

ARG 25 0.16 ASN 80 -0.19 ASP 21

ARG 25 0.16 ALA 81 -0.18 ASP 21

ASP 21 0.16 VAL 82 -0.18 ASP 21

ARG 25 0.16 GLN 83 -0.19 ASP 21

ARG 25 0.15 ILE 84 -0.18 ASP 21

ARG 25 0.15 GLU 85 -0.17 ASP 21

ARG 25 0.15 THR 86 -0.18 ASP 21

ARG 25 0.15 LEU 87 -0.18 ASP 21

ARG 25 0.14 LEU 88 -0.17 ASP 21

ARG 25 0.14 LEU 89 -0.17 ASP 21

ARG 25 0.14 LEU 90 -0.17 ALA 24

ARG 25 0.14 ARG 91 -0.17 ALA 24

ARG 25 0.13 ALA 92 -0.16 ALA 24

ARG 25 0.14 ILE 93 -0.16 ALA 24

ARG 25 0.14 ALA 94 -0.16 ALA 24

ARG 25 0.13 GLY 95 -0.16 ALA 24

ARG 25 0.12 PRO 96 -0.15 ALA 17

GLY 374 0.12 GLU 97 -0.15 ASP 5

ARG 25 0.13 ARG 98 -0.16 ALA 24

ARG 25 0.13 MET 99 -0.16 ALA 17

GLY 374 0.13 LYS 100 -0.16 ASP 5

GLY 374 0.14 PRO 101 -0.17 ASP 5

ARG 25 0.13 VAL 102 -0.17 ALA 17

ARG 25 0.13 LYS 103 -0.17 ALA 17

GLY 374 0.14 GLY 104 -0.17 ASP 5

GLY 374 0.14 GLU 105 -0.18 ASP 5

ARG 25 0.14 LEU 106 -0.19 ALA 17

GLY 374 0.14 LYS 107 -0.18 ASP 5

GLY 374 0.15 ARG 108 -0.19 ASP 5

GLY 374 0.14 LEU 109 -0.20 ASP 5

GLY 374 0.13 GLY 110 -0.20 ASP 5

ARG 25 0.14 ILE 111 -0.20 ALA 17

ARG 25 0.13 GLU 112 -0.19 ALA 17

ARG 25 0.13 VAL 113 -0.18 ALA 17

ARG 25 0.14 TRP 114 -0.19 ALA 17

ARG 25 0.13 THR 115 -0.18 ALA 17

ARG 25 0.14 PRO 116 -0.17 ALA 17

ARG 25 0.13 GLU 117 -0.17 ALA 17

ARG 25 0.14 GLY 118 -0.18 ALA 17

ARG 25 0.13 LYS 119 -0.18 ASP 5

GLY 374 0.12 GLU 120 -0.17 ASP 5

GLY 374 0.13 ASP 121 -0.17 ASP 5

ASP 67 0.20 MET 1 -0.06 LYS 35

GLY 110 0.19 ALA 2 -0.06 LYS 35

GLY 110 0.18 LEU 3 -0.06 LYS 35

GLY 110 0.19 GLY 4 -0.06 LYS 35

GLY 110 0.19 ASP 5 -0.05 LYS 35

GLU 117 0.17 PRO 6 -0.05 LYS 35

GLU 117 0.16 ILE 7 -0.06 LYS 35

GLU 117 0.15 GLN 8 -0.06 LYS 35

GLU 117 0.13 VAL 9 -0.06 LYS 35

GLU 117 0.11 ARG 10 -0.06 LYS 35

SER 57 0.10 LEU 11 -0.07 LYS 35

SER 57 0.08 SER 12 -0.07 GLY 46

GLU 117 0.07 PRO 13 -0.08 GLY 46

GLY 46 0.07 GLU 14 -0.09 GLY 46

GLY 46 0.09 LYS 15 -0.09 GLY 46

GLY 46 0.09 GLN 16 -0.08 GLY 46

GLY 46 0.08 ALA 17 -0.09 GLY 46

GLY 46 0.09 LEU 18 -0.10 GLY 46

GLY 46 0.11 LEU 19 -0.09 GLY 46

GLY 46 0.09 GLU 20 -0.08 GLY 46

GLY 46 0.09 ASP 21 -0.09 GLY 46

GLY 46 0.11 GLU 22 -0.10 GLY 46

GLY 46 0.10 ALA 23 -0.09 GLY 46

GLY 46 0.09 ALA 24 -0.08 GLY 46

GLY 46 0.10 ARG 25 -0.09 GLY 46

GLY 46 0.11 LYS 26 -0.09 ALA 2

GLY 46 0.09 GLY 27 -0.10 ALA 2

GLY 46 0.09 LYS 28 -0.08 GLY 46

GLY 110 0.10 ARG 29 -0.08 GLY 46

GLU 117 0.09 LEU 30 -0.08 GLY 46

GLU 117 0.11 ALA 31 -0.07 LYS 35

GLY 110 0.11 THR 32 -0.07 LYS 35

GLY 46 0.12 TYR 33 -0.08 GLY 46

GLY 46 0.12 LEU 34 -0.07 LYS 35

GLY 46 0.13 ARG 35 -0.07 LYS 35

GLY 46 0.15 GLU 36 -0.08 LYS 35

GLY 46 0.13 LEU 37 -0.09 GLN 45

GLY 46 0.15 LEU 38 -0.08 LYS 35

GLY 46 0.17 GLU 39 -0.08 LYS 35

GLY 46 0.18 SER 40 -0.09 GLN 45

GLY 46 0.21 GLU 41 -0.09 LYS 35

GLY 46 0.38 ASN 42 -0.09 LYS 35

GLY 46 0.27 ASP 43 -0.10 LYS 35

GLY 46 0.13 LEU 44 -0.10 LYS 35

ALA 49 0.18 GLN 45 -0.10 LYS 35

ASN 42 0.38 GLY 46 -0.11 LYS 35

LYS 26 0.16 GLU 47 -0.11 ALA 36

GLN 45 0.17 LEU 48 -0.11 ALA 36

ASN 42 0.20 ALA 49 -0.11 LYS 35

LEU 18 0.21 ALA 50 -0.11 ALA 36

LYS 26 0.16 LEU 51 -0.11 ASN 238

GLU 22 0.20 ARG 52 -0.11 ALA 36

LEU 18 0.25 ARG 53 -0.11 ALA 36

LEU 18 0.20 GLU 54 -0.13 ASP 21

GLU 22 0.20 VAL 55 -0.13 ARG 25

ARG 25 0.27 VAL 56 -0.12 ASP 21

ASP 21 0.27 SER 57 -0.14 ARG 25

ARG 25 0.22 LEU 58 -0.15 ASP 21

ARG 25 0.25 HIS 59 -0.15 ARG 25

ARG 25 0.28 HIS 60 -0.14 ASP 21

ASP 21 0.24 VAL 61 -0.17 ASP 21

ARG 25 0.22 ILE 62 -0.17 ASP 21

ARG 25 0.25 GLU 63 -0.15 ASP 21

ARG 25 0.27 ASP 64 -0.16 ASP 21

ARG 25 0.23 LEU 65 -0.19 ASP 21

ARG 25 0.23 ALA 66 -0.18 ASP 21

ARG 25 0.25 ASP 67 -0.17 ASP 21

ARG 25 0.23 THR 68 -0.18 ASP 21

ARG 25 0.21 GLY 69 -0.20 ASP 21

ARG 25 0.21 LEU 70 -0.18 ASP 21

ARG 25 0.22 ARG 71 -0.18 ASP 21

ASP 21 0.20 SER 72 -0.20 ASP 21

ARG 25 0.19 ASP 73 -0.20 ASP 21

ARG 25 0.20 GLN 74 -0.18 ASP 21

ASP 21 0.20 SER 75 -0.19 ASP 21

ASP 21 0.21 GLY 76 -0.18 ARG 25

ASP 21 0.21 PRO 77 -0.17 ARG 25

ASP 21 0.20 GLY 78 -0.17 ARG 25

ARG 25 0.19 GLN 79 -0.18 ARG 25

ASP 21 0.19 ASN 80 -0.18 ASP 21

ASP 21 0.18 ALA 81 -0.17 ARG 25

ARG 25 0.18 VAL 82 -0.18 ARG 25

ARG 25 0.17 GLN 83 -0.18 ARG 25

ASP 21 0.17 ILE 84 -0.17 ASP 21

ARG 25 0.17 GLU 85 -0.17 ARG 25

ARG 25 0.16 THR 86 -0.17 ARG 25

ARG 25 0.16 LEU 87 -0.17 ASP 21

ARG 25 0.15 LEU 88 -0.16 ASP 21

ARG 25 0.15 LEU 89 -0.16 ARG 25

ARG 25 0.15 LEU 90 -0.16 ALA 24

ARG 25 0.15 ARG 91 -0.16 ASP 21

ARG 25 0.14 ALA 92 -0.15 ALA 24

ARG 25 0.14 ILE 93 -0.16 ALA 24

ARG 25 0.14 ALA 94 -0.15 ALA 24

ARG 25 0.14 GLY 95 -0.15 ALA 24

ARG 25 0.13 PRO 96 -0.14 ASP 21

ARG 25 0.13 GLU 97 -0.14 ALA 24

ARG 25 0.13 ARG 98 -0.15 ALA 24

ARG 25 0.13 MET 99 -0.15 ASP 21

ALA 24 0.13 LYS 100 -0.15 ASP 21

ARG 25 0.13 PRO 101 -0.15 ALA 17

ARG 25 0.13 VAL 102 -0.16 ASP 21

ARG 25 0.14 LYS 103 -0.15 ALA 17

ARG 25 0.13 GLY 104 -0.15 ALA 17

ARG 25 0.13 GLU 105 -0.16 ALA 17

ARG 25 0.14 LEU 106 -0.16 ALA 17

ARG 25 0.14 LYS 107 -0.15 ALA 17

ARG 25 0.14 ARG 108 -0.16 ALA 17

ARG 25 0.14 LEU 109 -0.17 ALA 17

ARG 25 0.15 GLY 110 -0.16 ALA 17

ARG 25 0.15 ILE 111 -0.17 ALA 17

ARG 25 0.16 GLU 112 -0.16 ALA 17

ARG 25 0.15 VAL 113 -0.16 ALA 17

ARG 25 0.16 TRP 114 -0.16 ASP 21

ALA 24 0.16 THR 115 -0.15 ASP 21

ALA 24 0.17 PRO 116 -0.15 ASP 21

ALA 24 0.17 GLU 117 -0.14 ASP 21

ARG 25 0.17 GLY 118 -0.15 ASP 21

ARG 25 0.16 LYS 119 -0.14 ALA 17

ALA 24 0.15 GLU 120 -0.14 ASP 21

ALA 24 0.15 ASP 121 -0.13 ALA 17

VAL 56 0.17 MET 1 -0.04 ALA 2

GLY 46 0.14 ALA 2 -0.05 ASP 99

GLY 46 0.14 LEU 3 -0.06 ASP 99

GLY 46 0.14 THR 4 -0.05 ASP 99

GLY 46 0.14 LYS 5 -0.06 ASP 99

GLY 46 0.16 ALA 6 -0.05 LYS 35

GLY 46 0.16 GLU 7 -0.06 ASP 99

GLY 46 0.14 MET 8 -0.08 ASP 99

GLY 46 0.15 SER 9 -0.07 ASP 99

GLY 46 0.17 GLU 10 -0.07 ASP 99

GLY 46 0.15 TYR 11 -0.09 ASP 99

GLY 46 0.14 LEU 12 -0.09 ASP 99

GLY 46 0.16 PHE 13 -0.08 ASP 99

GLY 46 0.17 ASP 14 -0.09 ASP 99

GLY 46 0.14 LYS 15 -0.11 ASP 99

GLY 46 0.12 LEU 16 -0.11 ASP 99

GLY 46 0.14 GLY 17 -0.10 ASP 99

GLY 46 0.14 LEU 18 -0.09 ASP 99

GLY 46 0.15 SER 19 -0.08 ALA 24

GLY 46 0.16 LYS 20 -0.06 ALA 2

GLY 46 0.15 ARG 21 -0.08 ALA 2

GLY 46 0.13 ASP 22 -0.08 ARG 29

GLY 46 0.14 ALA 23 -0.08 ASP 99

GLY 46 0.14 LYS 24 -0.06 ASP 99

GLY 46 0.12 GLU 25 -0.07 ALA 2

GLY 46 0.11 LEU 26 -0.08 ASP 99

GLY 46 0.12 VAL 27 -0.08 ASP 99

GLY 46 0.12 GLU 28 -0.07 ASP 99

GLY 46 0.10 LEU 29 -0.08 ASP 99

GLY 46 0.10 PHE 30 -0.09 ASP 99

GLY 46 0.10 PHE 31 -0.08 ASP 99

GLY 46 0.10 GLU 32 -0.08 ASP 99

GLY 46 0.08 GLU 33 -0.09 ASP 99

GLY 46 0.08 ILE 34 -0.10 ASP 99

GLY 46 0.09 ARG 35 -0.08 ASP 99

GLY 46 0.08 ARG 36 -0.09 ASP 99

GLY 46 0.07 ALA 37 -0.10 ASP 99

GLY 46 0.07 LEU 38 -0.10 ASP 99

GLY 46 0.07 GLU 39 -0.08 ASP 99

GLY 46 0.07 ASN 40 -0.10 ASP 99

GLY 46 0.06 GLY 41 -0.10 ASP 99

GLY 46 0.06 GLU 42 -0.12 ASP 99

GLY 46 0.05 GLN 43 -0.13 ASP 99

GLY 46 0.06 VAL 44 -0.13 ASP 99

GLY 46 0.05 LYS 45 -0.14 ASP 99

GLY 46 0.05 LEU 46 -0.14 ASP 99

LYS 3 0.04 SER 47 -0.16 ASP 99

GLY 27 0.04 GLY 48 -0.17 ASP 99

GLY 27 0.05 PHE 49 -0.15 ASP 99

GLY 46 0.05 GLY 50 -0.14 ASP 99

GLY 46 0.05 ASN 51 -0.14 ASP 99

GLY 46 0.06 PHE 52 -0.12 ASP 99

GLY 46 0.06 ASP 53 -0.12 ASP 99

GLY 46 0.06 LEU 54 -0.11 ASP 99

GLY 46 0.06 ARG 55 -0.11 ASP 99

GLY 46 0.06 ASP 56 -0.10 ASP 99

GLY 374 0.06 LYS 57 -0.09 ASP 99

GLY 374 0.06 ASN 58 -0.08 ASP 99

GLY 374 0.07 GLN 59 -0.07 ASP 99

GLY 374 0.07 ARG 60 -0.07 ASP 99

GLY 374 0.08 PRO 61 -0.05 ASP 99

GLY 374 0.09 GLY 62 -0.04 ASP 99

GLY 374 0.10 ARG 63 -0.03 ASP 5

ASN 200 0.11 ASN 64 -0.03 ASP 5

THR 179 0.12 PRO 65 -0.02 ALA 2

THR 179 0.14 LYS 66 -0.02 ALA 2

THR 179 0.13 THR 67 -0.02 ASP 5

ASN 200 0.12 GLY 68 -0.02 ASP 5

ASN 200 0.10 GLU 69 -0.03 ASP 5

GLY 374 0.10 ASP 70 -0.03 ASP 5

GLY 374 0.09 ILE 71 -0.03 ASP 5

GLY 374 0.08 PRO 72 -0.04 ASP 99

GLY 374 0.08 ILE 73 -0.05 ASP 99

GLY 374 0.07 THR 74 -0.05 ASP 99

GLY 374 0.07 ALA 75 -0.07 ASP 99

GLY 46 0.07 ARG 76 -0.07 ASP 99

GLY 46 0.07 ARG 77 -0.08 ASP 99

GLY 46 0.07 VAL 78 -0.08 ASP 99

GLY 46 0.07 VAL 79 -0.09 ASP 99

GLY 46 0.07 THR 80 -0.10 ASP 99

GLY 46 0.06 PHE 81 -0.11 ASP 99

GLY 374 0.05 ARG 82 -0.14 ASP 99

GLY 27 0.06 PRO 83 -0.14 ASP 99

GLY 27 0.05 GLY 84 -0.16 ASP 99

GLY 27 0.07 GLN 85 -0.18 ASP 99

GLY 27 0.08 LYS 86 -0.18 ASP 99

GLY 27 0.09 LEU 87 -0.16 ASP 99

GLY 27 0.10 LYS 88 -0.16 ASP 99

GLY 27 0.12 SER 89 -0.18 ASP 99

GLY 27 0.13 ARG 90 -0.17 ASP 99

GLY 27 0.12 VAL 91 -0.15 ASP 99

GLY 27 0.13 GLU 92 -0.16 ASP 99

GLY 27 0.15 ASN 93 -0.16 ASP 99

GLY 27 0.14 ALA 94 -0.13 ASP 99

ASN 200 0.15 SER 95 -0.11 ASP 99

ASN 200 0.15 PRO 96 -0.09 ASP 99

THR 179 0.17 LYS 97 -0.09 MET 1

THR 179 0.20 ASP 98 -0.07 MET 1

THR 179 0.20 GLU 99 -0.06 ALA 2

GLY 46 0.05 MET 1 -0.13 ASP 99

GLY 46 0.05 THR 2 -0.14 ASP 99

GLY 46 0.05 LYS 3 -0.14 ASP 99

GLY 46 0.05 SER 4 -0.15 ASP 99

GLY 46 0.05 GLU 5 -0.13 ASP 99

GLY 46 0.07 LEU 6 -0.12 ASP 99

GLY 46 0.07 ILE 7 -0.13 ASP 99

GLY 46 0.06 GLU 8 -0.13 ASP 99

GLY 46 0.07 ARG 9 -0.11 ASP 99

GLY 46 0.08 LEU 10 -0.10 ASP 99

GLY 46 0.08 ALA 11 -0.11 ARG 29

GLY 46 0.08 THR 12 -0.11 ARG 29

GLY 46 0.09 GLN 13 -0.10 ARG 29

GLY 46 0.10 GLN 14 -0.11 ARG 29

GLY 46 0.09 SER 15 -0.13 ARG 29

GLY 46 0.10 HIS 16 -0.13 ARG 29

GLY 46 0.10 ILE 17 -0.13 ARG 29

GLY 46 0.08 PRO 18 -0.15 ARG 29

GLY 46 0.08 ALA 19 -0.12 ASP 99

GLY 46 0.07 LYS 20 -0.13 ASP 99

GLY 46 0.09 THR 21 -0.12 ASP 99

GLY 46 0.09 VAL 22 -0.11 ASP 99

GLY 46 0.07 GLU 23 -0.13 ASP 99

GLY 46 0.08 ASP 24 -0.13 ASP 99

GLY 46 0.10 ALA 25 -0.11 ASP 99

GLY 46 0.08 VAL 26 -0.12 ASP 99

GLY 46 0.07 LYS 27 -0.13 ASP 99

GLY 46 0.09 GLU 28 -0.12 ASP 99

GLY 46 0.10 MET 29 -0.11 ASP 99

GLY 46 0.08 LEU 30 -0.12 ASP 99

MET 1 0.11 GLU 31 -0.13 ASP 99

GLY 46 0.10 HIS 32 -0.11 ASP 99

GLY 46 0.09 MET 33 -0.11 ASP 99

GLY 27 0.08 ALA 34 -0.13 ASP 99

LYS 26 0.10 SER 35 -0.13 ASP 99

GLY 46 0.10 THR 36 -0.10 ASP 99

LYS 26 0.10 LEU 37 -0.11 ASP 99

GLY 27 0.12 ALA 38 -0.13 ASP 99

LYS 26 0.13 GLN 39 -0.11 ASP 99

ASN 200 0.13 GLY 40 -0.10 ASP 99

ASN 200 0.13 GLU 41 -0.08 ASP 99

ASN 200 0.12 ARG 42 -0.07 ASP 99

GLY 46 0.12 ILE 43 -0.07 ASP 99

GLY 46 0.12 GLU 44 -0.05 ASP 99

GLY 46 0.12 ILE 45 -0.06 ASP 99

GLY 46 0.12 ARG 46 -0.04 ALA 2

GLY 46 0.11 GLY 47 -0.05 ALA 2

GLY 46 0.10 PHE 48 -0.06 ASP 99

GLY 46 0.10 GLY 49 -0.06 ASP 99

GLY 46 0.10 SER 50 -0.07 ASP 99

GLY 46 0.09 PHE 51 -0.08 ASP 99

ASN 200 0.10 SER 52 -0.08 ASP 99

ASN 200 0.11 LEU 53 -0.10 ASP 99

ASN 200 0.11 HIS 54 -0.10 ASP 99

ASN 200 0.12 TYR 55 -0.11 ASP 99

ASN 200 0.10 ARG 56 -0.13 ASP 99

ASN 200 0.12 ALA 57 -0.13 ASP 99

GLY 27 0.11 PRO 58 -0.16 ASP 99

GLY 27 0.10 ARG 59 -0.16 ASP 99

GLY 27 0.09 THR 60 -0.19 ASP 99

GLY 27 0.08 GLY 61 -0.19 ASP 99

GLY 27 0.07 ARG 62 -0.21 ASP 99

GLY 27 0.06 ASN 63 -0.23 THR 435

GLY 27 0.05 PRO 64 -0.22 THR 435

GLY 27 0.04 LYS 65 -0.25 THR 435

GLY 27 0.05 THR 66 -0.27 THR 435

GLY 27 0.05 GLY 67 -0.24 THR 435

GLY 27 0.07 ASP 68 -0.25 THR 435

GLY 27 0.08 LYS 69 -0.23 THR 435

GLY 27 0.09 VAL 70 -0.23 ASP 99

GLY 27 0.11 GLU 71 -0.21 ASP 99

GLY 27 0.11 LEU 72 -0.19 ASP 99

GLY 27 0.13 GLU 73 -0.18 ASP 99

GLY 27 0.12 GLY 74 -0.15 ASP 99

GLY 27 0.12 LYS 75 -0.15 ASP 99

GLY 27 0.11 TYR 76 -0.13 ASP 99

GLY 27 0.10 VAL 77 -0.13 ASP 99

GLY 27 0.09 PRO 78 -0.12 ASP 99

ASN 200 0.07 HIS 79 -0.10 ASP 99

GLY 46 0.08 PHE 80 -0.09 ASP 99

GLY 46 0.09 LYS 81 -0.07 ASP 99

GLY 46 0.09 PRO 82 -0.07 ASP 99

GLY 46 0.10 GLY 83 -0.05 ASP 99

GLY 46 0.10 LYS 84 -0.04 ALA 2

GLY 46 0.10 GLU 85 -0.05 ALA 2

GLY 46 0.09 LEU 86 -0.06 ASP 99

GLY 46 0.09 ARG 87 -0.06 ASP 99

GLY 46 0.09 ASP 88 -0.05 ASP 99

GLY 46 0.09 ARG 89 -0.06 ASP 99

GLY 46 0.08 ALA 90 -0.08 ASP 99

GLY 46 0.08 ASN 91 -0.07 ASP 99

GLY 46 0.07 ILE 92 -0.07 ASP 99

GLY 46 0.07 TYR 93 -0.07 ASP 99

GLY 46 0.08 GLY 94 -0.05 ASP 99

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** ***

CA distance fluctuations for 260211153256928911

--- normal mode 11 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* *