Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* *

CA distance fluctuations for 260211153256928911

--- normal mode 9 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
LYS 119 0.10 MET 1 -0.07 GLY 46

LYS 119 0.11 ALA 2 -0.07 LYS 119

LYS 119 0.12 LEU 3 -0.07 LYS 119

LYS 119 0.12 GLY 4 -0.08 LYS 119

LYS 119 0.12 ASP 5 -0.08 LYS 119

LYS 119 0.14 PRO 6 -0.08 LYS 119

LYS 119 0.14 ILE 7 -0.08 LYS 119

LYS 119 0.15 GLN 8 -0.08 GLY 110

LYS 119 0.16 VAL 9 -0.09 GLY 110

LYS 119 0.17 ARG 10 -0.09 GLY 110

LYS 119 0.17 LEU 11 -0.09 GLY 110

LYS 119 0.18 SER 12 -0.09 GLY 110

LYS 119 0.20 PRO 13 -0.07 GLY 110

LYS 119 0.21 GLU 14 -0.08 GLY 110

LYS 119 0.19 LYS 15 -0.08 GLY 110

LYS 119 0.20 GLN 16 -0.07 GLY 110

LYS 119 0.22 ALA 17 -0.06 GLY 110

LYS 119 0.21 LEU 18 -0.06 GLY 110

LYS 119 0.19 LEU 19 -0.07 GLY 110

LYS 119 0.21 GLU 20 -0.05 GLY 110

LYS 119 0.23 ASP 21 -0.05 GLY 110

LYS 119 0.21 GLU 22 -0.05 GLY 110

LYS 119 0.20 ALA 23 -0.05 GLY 110

LYS 119 0.22 ALA 24 -0.04 GLY 110

LYS 119 0.22 ARG 25 -0.05 GLY 46

LYS 119 0.20 LYS 26 -0.05 GLY 46

GLY 110 0.21 GLY 27 -0.04 GLY 46

LYS 119 0.19 LYS 28 -0.04 GLY 110

LYS 119 0.19 ARG 29 -0.05 GLY 110

LYS 119 0.18 LEU 30 -0.06 GLY 110

LYS 119 0.17 ALA 31 -0.06 GLY 110

LYS 119 0.16 THR 32 -0.06 GLY 110

LYS 119 0.16 TYR 33 -0.06 GLY 110

LYS 119 0.16 LEU 34 -0.07 GLY 110

LYS 119 0.14 ARG 35 -0.08 GLY 110

LYS 119 0.13 GLU 36 -0.07 GLY 110

LYS 119 0.14 LEU 37 -0.08 GLY 110

LYS 119 0.13 LEU 38 -0.09 LYS 119

LYS 119 0.11 GLU 39 -0.09 LYS 119

GLY 110 0.11 SER 40 -0.09 LYS 119

GLY 110 0.10 GLU 41 -0.11 LYS 119

GLY 110 0.09 ASN 42 -0.11 GLY 118

GLY 110 0.11 ASP 43 -0.09 LYS 119

GLY 110 0.10 LEU 44 -0.11 GLY 118

GLY 110 0.08 GLN 45 -0.12 GLY 118

GLY 110 0.09 GLY 46 -0.10 GLY 118

GLY 110 0.10 GLU 47 -0.10 GLY 118

GLY 110 0.09 LEU 48 -0.12 GLY 118

GLY 110 0.08 ALA 49 -0.11 GLY 118

GLY 110 0.09 ALA 50 -0.09 GLY 118

GLY 110 0.10 LEU 51 -0.10 GLY 118

GLY 110 0.08 ARG 52 -0.12 ASP 67

GLY 110 0.07 ARG 53 -0.11 ASP 67

GLY 110 0.09 GLU 54 -0.09 GLY 118

GLY 110 0.09 VAL 55 -0.11 GLY 118

GLY 110 0.07 VAL 56 -0.12 ASP 67

GLY 110 0.07 SER 57 -0.09 ASP 67

GLY 110 0.09 LEU 58 -0.10 PRO 77

GLY 118 0.07 HIS 59 -0.12 PRO 77

ARG 53 0.06 HIS 60 -0.12 LEU 70

ARG 25 0.07 VAL 61 -0.09 ARG 25

GLY 118 0.07 ILE 62 -0.11 PRO 77

ASP 99 0.06 GLU 63 -0.13 LEU 70

ARG 25 0.07 ASP 64 -0.13 GLU 63

ARG 25 0.07 LEU 65 -0.10 ARG 25

GLY 118 0.06 ALA 66 -0.13 ARG 25

GLU 63 0.06 ASP 67 -0.14 ARG 25

ARG 25 0.08 THR 68 -0.12 ARG 25

ARG 25 0.07 GLY 69 -0.10 ARG 25

ARG 25 0.06 LEU 70 -0.13 ARG 25

ARG 25 0.07 ARG 71 -0.12 ARG 25

ARG 25 0.08 SER 72 -0.10 ARG 25

ARG 25 0.07 ASP 73 -0.10 ARG 25

ARG 25 0.09 GLN 74 -0.09 ARG 25

SER 72 0.13 SER 75 -0.07 ARG 25

LEU 70 0.16 GLY 76 -0.04 ARG 25

LEU 70 0.17 PRO 77 -0.04 ASN 80

LEU 70 0.14 GLY 78 -0.05 ASN 80

ARG 25 0.11 GLN 79 -0.06 ARG 25

ARG 25 0.13 ASN 80 -0.05 ARG 25

ASP 21 0.13 ALA 81 -0.04 ARG 25

ASP 21 0.12 VAL 82 -0.06 ARG 25

ARG 25 0.12 GLN 83 -0.07 ARG 25

ARG 25 0.14 ILE 84 -0.05 ARG 25

ASP 21 0.13 GLU 85 -0.05 ARG 25

ARG 25 0.12 THR 86 -0.07 ARG 25

ARG 25 0.13 LEU 87 -0.07 ARG 25

ASP 21 0.14 LEU 88 -0.06 ARG 25

ARG 25 0.13 LEU 89 -0.07 ARG 25

ARG 25 0.12 LEU 90 -0.08 ARG 25

ARG 25 0.14 ARG 91 -0.07 ARG 25

ASP 21 0.13 ALA 92 -0.06 ARG 25

ARG 25 0.12 ILE 93 -0.08 ARG 25

ARG 25 0.13 ALA 94 -0.08 ARG 25

ARG 25 0.14 GLY 95 -0.07 ARG 25

ASP 21 0.15 PRO 96 -0.06 ASP 21

ARG 25 0.15 GLU 97 -0.07 ASP 21

ARG 25 0.14 ARG 98 -0.07 ASP 21

ARG 25 0.15 MET 99 -0.07 ASP 21

ARG 25 0.16 LYS 100 -0.06 ASP 21

ARG 25 0.16 PRO 101 -0.07 ASP 21

ARG 25 0.16 VAL 102 -0.07 ASP 21

ARG 25 0.18 LYS 103 -0.06 ASP 21

ARG 25 0.18 GLY 104 -0.06 ASP 21

ARG 25 0.18 GLU 105 -0.07 ASP 21

ARG 25 0.19 LEU 106 -0.06 ASP 21

ARG 25 0.20 LYS 107 -0.05 ASP 21

ARG 25 0.20 ARG 108 -0.06 ASP 21

ARG 25 0.20 LEU 109 -0.06 ASP 21

ARG 25 0.22 GLY 110 -0.05 VAL 61

ARG 25 0.21 ILE 111 -0.05 ASP 21

ARG 25 0.21 GLU 112 -0.04 VAL 61

ARG 25 0.19 VAL 113 -0.05 ASP 21

ARG 25 0.19 TRP 114 -0.04 ASP 21

ASP 21 0.19 THR 115 -0.03 ASP 21

ASP 21 0.20 PRO 116 -0.03 VAL 61

ASP 21 0.22 GLU 117 -0.03 GLU 63

ASP 21 0.22 GLY 118 -0.03 VAL 61

ASP 21 0.23 LYS 119 -0.03 VAL 61

ASP 21 0.21 GLU 120 -0.03 VAL 61

ASP 21 0.22 ASP 121 -0.03 VAL 61

GLY 110 0.19 MET 1 -0.09 GLY 110

ASP 121 0.19 ALA 2 -0.09 GLY 110

LYS 119 0.18 LEU 3 -0.08 GLY 110

LYS 119 0.19 GLY 4 -0.07 GLY 110

LYS 119 0.19 ASP 5 -0.07 GLY 110

LYS 119 0.17 PRO 6 -0.07 GLY 110

LYS 119 0.17 ILE 7 -0.07 GLY 110

LYS 119 0.16 GLN 8 -0.07 GLY 110

LYS 119 0.15 VAL 9 -0.07 GLY 110

LYS 119 0.14 ARG 10 -0.07 LYS 119

LYS 119 0.12 LEU 11 -0.08 LYS 119

LYS 119 0.11 SER 12 -0.09 LYS 119

LYS 119 0.10 PRO 13 -0.09 LYS 119

GLY 110 0.09 GLU 14 -0.10 LYS 119

GLY 110 0.10 LYS 15 -0.10 LYS 119

LYS 119 0.11 GLN 16 -0.10 LYS 119

GLY 110 0.10 ALA 17 -0.11 LYS 119

GLY 110 0.10 LEU 18 -0.12 LYS 119

GLY 110 0.11 LEU 19 -0.12 LYS 119

GLY 110 0.11 GLU 20 -0.12 LYS 119

GLY 110 0.10 ASP 21 -0.13 LYS 119

GLY 110 0.11 GLU 22 -0.13 LYS 119

GLY 110 0.11 ALA 23 -0.13 LYS 119

GLY 110 0.11 ALA 24 -0.13 LYS 119

GLY 110 0.10 ARG 25 -0.14 LYS 119

GLY 110 0.11 LYS 26 -0.14 LYS 119

GLY 110 0.11 GLY 27 -0.14 LYS 119

GLY 110 0.12 LYS 28 -0.13 LYS 119

GLY 110 0.12 ARG 29 -0.12 LYS 119

GLY 110 0.12 LEU 30 -0.11 LYS 119

LYS 119 0.14 ALA 31 -0.10 LYS 119

GLY 110 0.14 THR 32 -0.11 LYS 119

GLY 110 0.13 TYR 33 -0.12 LYS 119

GLY 110 0.13 LEU 34 -0.11 LYS 119

GLY 110 0.15 ARG 35 -0.10 GLY 110

GLY 110 0.14 GLU 36 -0.11 GLY 110

GLY 110 0.13 LEU 37 -0.12 GLY 110

GLY 110 0.15 LEU 38 -0.10 GLY 110

GLY 110 0.16 GLU 39 -0.11 GLY 110

GLY 110 0.14 SER 40 -0.12 GLY 110

GLY 110 0.14 GLU 41 -0.11 GLY 110

GLY 110 0.16 ASN 42 -0.10 GLY 110

GLY 46 0.16 ASP 43 -0.12 GLY 110

GLY 110 0.13 LEU 44 -0.13 GLY 110

GLY 110 0.14 GLN 45 -0.10 GLY 110

ASP 43 0.16 GLY 46 -0.10 GLY 110

GLY 110 0.14 GLU 47 -0.12 GLY 110

GLY 110 0.13 LEU 48 -0.11 GLY 110

GLY 110 0.14 ALA 49 -0.10 GLY 110

GLY 110 0.15 ALA 50 -0.10 GLY 110

GLY 110 0.14 LEU 51 -0.11 GLY 110

GLY 110 0.13 ARG 52 -0.10 GLY 110

GLY 110 0.16 ARG 53 -0.08 GLY 110

GLY 110 0.15 GLU 54 -0.10 GLY 110

GLY 110 0.12 VAL 55 -0.10 GLY 110

GLY 110 0.13 VAL 56 -0.08 GLY 110

GLY 110 0.15 SER 57 -0.08 GLY 110

GLY 110 0.13 LEU 58 -0.09 GLY 110

GLY 110 0.12 HIS 59 -0.08 GLY 110

GLY 110 0.14 HIS 60 -0.06 GLY 110

ASP 64 0.17 VAL 61 -0.07 GLY 110

GLY 110 0.12 ILE 62 -0.07 GLY 110

ALA 66 0.14 GLU 63 -0.06 ARG 25

VAL 61 0.17 ASP 64 -0.06 GLY 110

GLY 110 0.12 LEU 65 -0.07 PRO 77

GLU 63 0.14 ALA 66 -0.07 ARG 25

GLY 76 0.14 ASP 67 -0.06 ARG 25

GLY 76 0.15 THR 68 -0.05 ARG 25

ARG 25 0.10 GLY 69 -0.07 ARG 25

GLN 74 0.12 LEU 70 -0.08 ARG 25

GLN 74 0.22 ARG 71 -0.07 ARG 25

SER 75 0.15 SER 72 -0.07 ARG 25

ARG 25 0.11 ASP 73 -0.08 ARG 25

ARG 71 0.22 GLN 74 -0.07 ARG 25

ARG 71 0.18 SER 75 -0.07 ARG 25

ARG 71 0.19 GLY 76 -0.05 ARG 25

ARG 25 0.18 PRO 77 -0.05 ARG 25

ARG 25 0.18 GLY 78 -0.05 ARG 25

ARG 25 0.15 GLN 79 -0.07 ARG 25

ARG 25 0.15 ASN 80 -0.08 ARG 25

ARG 25 0.17 ALA 81 -0.07 ARG 25

ARG 25 0.15 VAL 82 -0.07 ARG 25

ARG 25 0.14 GLN 83 -0.09 ARG 25

ARG 25 0.15 ILE 84 -0.09 ARG 25

ARG 25 0.15 GLU 85 -0.08 ARG 25

ARG 25 0.13 THR 86 -0.09 ARG 25

ARG 25 0.14 LEU 87 -0.10 ARG 25

ARG 25 0.15 LEU 88 -0.09 ASP 21

ARG 25 0.14 LEU 89 -0.09 ARG 25

ARG 25 0.12 LEU 90 -0.11 ARG 25

ARG 25 0.14 ARG 91 -0.10 ARG 25

ARG 25 0.14 ALA 92 -0.09 ARG 25

ARG 25 0.12 ILE 93 -0.10 ARG 25

ARG 25 0.12 ALA 94 -0.11 ARG 25

ARG 25 0.13 GLY 95 -0.10 ASP 21

ARG 25 0.14 PRO 96 -0.10 ASP 21

ALA 17 0.13 GLU 97 -0.10 ASP 21

ALA 17 0.13 ARG 98 -0.11 ASP 21

ALA 17 0.14 MET 99 -0.11 ASP 21

ALA 17 0.14 LYS 100 -0.11 ASP 21

ASP 21 0.14 PRO 101 -0.12 ASP 21

ASP 21 0.14 VAL 102 -0.12 ASP 21

ALA 17 0.15 LYS 103 -0.11 ASP 21

ASP 21 0.16 GLY 104 -0.11 ASP 21

ASP 21 0.16 GLU 105 -0.13 ASP 21

ASP 21 0.16 LEU 106 -0.12 ASP 21

ASP 21 0.17 LYS 107 -0.11 ASP 21

ALA 24 0.18 ARG 108 -0.12 ASP 21

ALA 24 0.18 LEU 109 -0.13 ASP 21

ASP 21 0.19 GLY 110 -0.12 ASP 21

ASP 21 0.18 ILE 111 -0.12 ASP 21

ASP 21 0.19 GLU 112 -0.10 ASP 21

ALA 17 0.17 VAL 113 -0.10 ASP 21

ARG 25 0.17 TRP 114 -0.10 ASP 21

ARG 25 0.18 THR 115 -0.08 ASP 21

ARG 25 0.19 PRO 116 -0.07 ASP 21

ARG 25 0.20 GLU 117 -0.07 ASP 21

ALA 17 0.20 GLY 118 -0.08 ASP 21

ALA 17 0.20 LYS 119 -0.08 ASP 21

ALA 17 0.18 GLU 120 -0.08 ASP 21

ALA 17 0.19 ASP 121 -0.08 ASP 21

ASP 99 0.09 MET 1 -0.22 LYS 119

ASP 99 0.09 ALA 2 -0.23 LYS 119

ASP 99 0.08 LEU 3 -0.23 LYS 119

ASP 99 0.08 GLY 4 -0.21 LYS 119

ASP 99 0.08 ASP 5 -0.22 LYS 119

ASP 99 0.07 PRO 6 -0.23 LYS 119

ASP 99 0.07 ILE 7 -0.22 LYS 119

ASP 99 0.06 GLN 8 -0.22 LYS 119

ASP 99 0.06 VAL 9 -0.22 GLU 117

ASP 99 0.06 ARG 10 -0.22 GLU 117

THR 435 0.06 LEU 11 -0.23 GLU 117

THR 435 0.06 SER 12 -0.23 GLY 110

THR 435 0.06 PRO 13 -0.26 GLY 110

THR 435 0.06 GLU 14 -0.26 GLY 110

THR 435 0.06 LYS 15 -0.24 GLY 110

THR 435 0.06 GLN 16 -0.26 GLU 117

THR 435 0.06 ALA 17 -0.28 GLU 117

THR 435 0.06 LEU 18 -0.27 GLY 118

THR 435 0.06 LEU 19 -0.27 GLY 118

THR 435 0.06 GLU 20 -0.29 GLY 118

THR 435 0.06 ASP 21 -0.31 GLY 118

THR 435 0.07 GLU 22 -0.29 GLY 118

THR 435 0.07 ALA 23 -0.29 GLY 118

THR 435 0.07 ALA 24 -0.33 GLY 118

THR 435 0.07 ARG 25 -0.33 GLY 118

THR 435 0.07 LYS 26 -0.31 LYS 119

THR 435 0.07 GLY 27 -0.33 LYS 119

THR 435 0.07 LYS 28 -0.30 LYS 119

THR 435 0.06 ARG 29 -0.30 LYS 119

THR 435 0.06 LEU 30 -0.28 LYS 119

ASP 99 0.07 ALA 31 -0.26 LYS 119

ASP 99 0.07 THR 32 -0.26 LYS 119

ASP 99 0.07 TYR 33 -0.26 LYS 119

ASP 99 0.07 LEU 34 -0.24 LYS 119

ASP 99 0.08 ARG 35 -0.23 LYS 119

ASP 99 0.08 GLU 36 -0.23 LYS 119

ASP 99 0.08 LEU 37 -0.22 LYS 119

ASP 99 0.08 LEU 38 -0.20 LYS 119

ASP 99 0.09 GLU 39 -0.20 LYS 119

ASP 99 0.09 SER 40 -0.20 LYS 119

LYS 119 0.10 GLU 41 -0.17 LYS 119

GLY 110 0.11 ASN 42 -0.17 LYS 119

LYS 119 0.10 ASP 43 -0.18 LYS 119

GLY 110 0.10 LEU 44 -0.16 LYS 119

GLY 110 0.12 GLN 45 -0.15 GLY 110

LYS 119 0.11 GLY 46 -0.16 GLY 110

LYS 119 0.10 GLU 47 -0.17 GLY 110

GLY 110 0.11 LEU 48 -0.15 GLY 110

GLY 110 0.12 ALA 49 -0.15 GLY 110

LYS 119 0.11 ALA 50 -0.17 GLY 110

GLY 110 0.11 LEU 51 -0.16 GLY 110

GLY 110 0.13 ARG 52 -0.14 GLY 110

LYS 119 0.13 ARG 53 -0.15 GLY 110

GLY 118 0.11 GLU 54 -0.16 GLY 110

GLY 110 0.12 VAL 55 -0.14 GLY 110

GLY 110 0.13 VAL 56 -0.13 GLY 110

GLY 118 0.13 SER 57 -0.15 GLY 110

GLY 118 0.12 LEU 58 -0.14 GLY 110

GLY 110 0.14 HIS 59 -0.12 GLY 110

GLY 118 0.15 HIS 60 -0.13 GLY 110

GLY 118 0.13 VAL 61 -0.14 GLY 110

GLY 118 0.13 ILE 62 -0.11 GLY 110

GLY 118 0.16 GLU 63 -0.10 GLY 110

GLY 118 0.14 ASP 64 -0.11 GLY 110

GLY 118 0.12 LEU 65 -0.10 GLY 110

GLY 118 0.13 ALA 66 -0.08 GLY 110

GLY 118 0.16 ASP 67 -0.08 GLY 118

GLY 118 0.14 THR 68 -0.09 GLN 74

GLY 118 0.11 GLY 69 -0.07 ASP 73

PRO 77 0.17 LEU 70 -0.05 GLY 118

GLN 74 0.18 ARG 71 -0.06 ASP 73

GLN 74 0.10 SER 72 -0.09 ASP 73

LEU 70 0.11 ASP 73 -0.05 ARG 25

ARG 71 0.18 GLN 74 -0.04 GLY 118

ARG 71 0.07 SER 75 -0.06 ARG 25

ILE 111 0.08 GLY 76 -0.05 ARG 25

ILE 111 0.12 PRO 77 -0.05 ILE 111

ASP 227 0.08 GLY 78 -0.06 GLY 27

ASP 227 0.06 GLN 79 -0.08 ARG 25

ASP 227 0.07 ASN 80 -0.06 ARG 25

ASP 227 0.08 ALA 81 -0.05 ARG 25

ALA 81 0.07 VAL 82 -0.08 ARG 25

ARG 25 0.08 GLN 83 -0.07 ARG 25

ARG 71 0.09 ILE 84 -0.05 ARG 25

ASP 21 0.08 GLU 85 -0.06 ARG 25

ARG 25 0.08 THR 86 -0.08 ARG 25

ASP 21 0.10 LEU 87 -0.06 ARG 25

ASP 21 0.10 LEU 88 -0.05 ARG 25

ASP 21 0.09 LEU 89 -0.07 ARG 25

ARG 25 0.10 LEU 90 -0.07 ARG 25

ASP 21 0.11 ARG 91 -0.06 ARG 25

ASP 21 0.10 ALA 92 -0.06 ARG 25

ASP 21 0.10 ILE 93 -0.07 ARG 25

ASP 21 0.11 ALA 94 -0.07 ARG 25

ASP 21 0.11 GLY 95 -0.05 ARG 25

ASP 21 0.12 PRO 96 -0.04 GLU 105

ASP 21 0.13 GLU 97 -0.04 ASP 21

ASP 21 0.13 ARG 98 -0.05 GLY 95

ASP 21 0.14 MET 99 -0.04 ALA 92

ASP 21 0.15 LYS 100 -0.05 PRO 96

ASP 21 0.16 PRO 101 -0.05 PRO 96

ASP 21 0.15 VAL 102 -0.04 ALA 92

ASP 21 0.16 LYS 103 -0.03 PRO 96

ASP 21 0.17 GLY 104 -0.03 PRO 96

ASP 21 0.18 GLU 105 -0.03 PRO 96

ASP 21 0.17 LEU 106 -0.02 PRO 96

ALA 17 0.18 LYS 107 -0.02 PRO 96

ASP 21 0.20 ARG 108 -0.02 PRO 96

ASP 21 0.20 LEU 109 -0.02 GLU 63

ASP 21 0.21 GLY 110 -0.01 GLU 63

ASP 21 0.18 ILE 111 -0.01 ALA 81

GLU 14 0.18 GLU 112 -0.02 ALA 92

ALA 17 0.16 VAL 113 -0.03 ALA 92

ASP 21 0.14 TRP 114 -0.02 ALA 92

GLU 14 0.14 THR 115 -0.03 ALA 92

GLU 14 0.13 PRO 116 -0.05 LEU 109

GLU 14 0.15 GLU 117 -0.02 GLY 110

ASP 67 0.16 GLY 118 -0.02 GLY 110

GLU 14 0.18 LYS 119 -0.02 PRO 96

GLU 14 0.17 GLU 120 -0.03 PRO 96

GLU 14 0.18 ASP 121 -0.03 PRO 96

THR 435 0.05 MET 1 -0.22 GLY 110

THR 435 0.05 ALA 2 -0.23 GLY 110

THR 435 0.06 LEU 3 -0.23 GLY 110

THR 435 0.06 GLY 4 -0.25 GLY 110

THR 435 0.06 ASP 5 -0.26 GLU 117

THR 435 0.06 PRO 6 -0.24 GLU 117

ARG 427 0.06 ILE 7 -0.25 LYS 119

ASP 99 0.06 GLN 8 -0.24 LYS 119

ASP 99 0.07 VAL 9 -0.24 LYS 119

ASP 99 0.08 ARG 10 -0.23 LYS 119

ASP 99 0.08 LEU 11 -0.22 LYS 119

ASP 99 0.09 SER 12 -0.21 LYS 119

ASP 99 0.09 PRO 13 -0.20 LYS 119

ASP 99 0.10 GLU 14 -0.18 LYS 119

ASP 99 0.09 LYS 15 -0.19 LYS 119

ASP 99 0.09 GLN 16 -0.19 LYS 119

ASP 99 0.09 ALA 17 -0.18 LYS 119

ASP 99 0.09 LEU 18 -0.17 LYS 119

ASP 99 0.09 LEU 19 -0.18 LYS 119

ASP 99 0.08 GLU 20 -0.17 LYS 119

GLY 110 0.09 ASP 21 -0.16 LYS 119

GLY 110 0.09 GLU 22 -0.16 LYS 119

ASP 99 0.08 ALA 23 -0.16 LYS 119

ASP 99 0.08 ALA 24 -0.15 LYS 119

GLY 110 0.09 ARG 25 -0.14 LYS 119

GLY 110 0.08 LYS 26 -0.14 LYS 119

ASP 99 0.08 GLY 27 -0.14 LYS 119

ASP 99 0.07 LYS 28 -0.16 LYS 119

ASP 99 0.07 ARG 29 -0.17 LYS 119

ASP 99 0.08 LEU 30 -0.18 LYS 119

ASP 99 0.07 ALA 31 -0.20 LYS 119

ASP 99 0.07 THR 32 -0.18 GLU 117

ASP 99 0.07 TYR 33 -0.18 LYS 119

ASP 99 0.07 LEU 34 -0.19 LYS 119

ASP 99 0.07 ARG 35 -0.20 GLU 117

ASP 99 0.07 GLU 36 -0.18 GLU 117

ASP 99 0.08 LEU 37 -0.18 LYS 119

ASP 99 0.07 LEU 38 -0.20 GLY 118

ASP 99 0.06 GLU 39 -0.20 GLU 117

ASP 99 0.07 SER 40 -0.17 GLY 118

ASP 99 0.08 GLU 41 -0.18 GLY 118

ASP 99 0.07 ASN 42 -0.19 GLY 118

ASP 99 0.07 ASP 43 -0.17 GLY 118

ASP 99 0.08 LEU 44 -0.16 GLY 118

ASP 99 0.08 GLN 45 -0.18 GLY 118

ASP 99 0.07 GLY 46 -0.18 GLY 118

ASP 99 0.07 GLU 47 -0.16 GLY 118

LYS 119 0.08 LEU 48 -0.16 GLY 118

ASP 99 0.08 ALA 49 -0.18 GLY 118

ASP 99 0.07 ALA 50 -0.18 GLY 118

GLY 118 0.08 LEU 51 -0.16 GLY 118

GLY 118 0.09 ARG 52 -0.17 GLY 118

ASP 99 0.07 ARG 53 -0.19 GLY 118

ASP 99 0.07 GLU 54 -0.17 ASP 67

GLY 118 0.09 VAL 55 -0.15 GLY 110

GLY 118 0.09 VAL 56 -0.18 GLY 110

GLY 118 0.07 SER 57 -0.18 PRO 77

GLY 118 0.08 LEU 58 -0.16 PRO 77

GLY 118 0.09 HIS 59 -0.17 GLY 110

GLY 118 0.08 HIS 60 -0.20 PRO 77

GLY 118 0.07 VAL 61 -0.19 PRO 77

GLY 118 0.09 ILE 62 -0.16 PRO 77

GLY 118 0.09 GLU 63 -0.18 GLY 110

GLY 110 0.08 ASP 64 -0.20 PRO 77

GLY 118 0.08 LEU 65 -0.16 PRO 77

GLY 118 0.10 ALA 66 -0.14 PRO 77

GLY 110 0.09 ASP 67 -0.16 GLY 110

GLY 110 0.06 THR 68 -0.18 PRO 77

GLY 110 0.07 GLY 69 -0.11 PRO 77

GLY 110 0.09 LEU 70 -0.11 GLY 76

THR 435 0.06 ARG 71 -0.21 GLY 76

GLU 63 0.07 SER 72 -0.15 SER 75

GLY 226 0.06 ASP 73 -0.09 ARG 25

GLY 226 0.06 GLN 74 -0.15 ARG 71

GLY 226 0.05 SER 75 -0.18 ARG 71

ASP 67 0.06 GLY 76 -0.21 ARG 71

GLY 226 0.05 PRO 77 -0.16 GLY 27

ARG 25 0.05 GLY 78 -0.18 GLY 27

ARG 25 0.05 GLN 79 -0.16 ARG 25

GLY 226 0.05 ASN 80 -0.13 ARG 25

ARG 25 0.04 ALA 81 -0.14 GLY 27

ARG 25 0.05 VAL 82 -0.16 ARG 25

ARG 25 0.05 GLN 83 -0.13 ARG 25

GLY 226 0.05 ILE 84 -0.11 GLY 27

ARG 25 0.05 GLU 85 -0.13 GLY 27

ARG 25 0.05 THR 86 -0.13 ARG 25

ARG 25 0.06 LEU 87 -0.10 ARG 25

ARG 25 0.05 LEU 88 -0.11 GLY 27

ARG 25 0.06 LEU 89 -0.12 ARG 25

ARG 25 0.07 LEU 90 -0.10 ARG 25

ARG 25 0.07 ARG 91 -0.09 ARG 25

ARG 25 0.06 ALA 92 -0.11 ARG 25

ARG 25 0.07 ILE 93 -0.11 ARG 25

ARG 25 0.08 ALA 94 -0.09 ARG 25

ARG 25 0.07 GLY 95 -0.08 ARG 25

ARG 25 0.07 PRO 96 -0.07 THR 66

ASP 21 0.08 GLU 97 -0.06 ALA 24

ASP 21 0.09 ARG 98 -0.06 ARG 25

ASP 21 0.08 MET 99 -0.06 ARG 25

ASP 21 0.08 LYS 100 -0.04 ALA 24

ALA 17 0.10 PRO 101 -0.06 ALA 92

ASP 21 0.09 VAL 102 -0.05 ALA 92

ASP 227 0.08 LYS 103 -0.03 ARG 25

GLU 14 0.10 GLY 104 -0.04 ALA 92

GLU 14 0.11 GLU 105 -0.04 ALA 92

ARG 71 0.10 LEU 106 -0.03 ALA 92

ASP 227 0.10 LYS 107 -0.03 PRO 96

GLU 14 0.11 ARG 108 -0.04 PRO 96

ARG 71 0.13 LEU 109 -0.05 PRO 116

ASP 67 0.12 GLY 110 -0.03 PRO 116

PRO 77 0.12 ILE 111 -0.02 PRO 116

ASP 227 0.10 GLU 112 -0.02 ALA 92

ASP 227 0.10 VAL 113 -0.03 THR 66

ASP 227 0.08 TRP 114 -0.05 THR 66

GLY 226 0.09 THR 115 -0.07 THR 66

GLY 226 0.08 PRO 116 -0.09 THR 66

GLY 226 0.09 GLU 117 -0.08 ASP 68

GLY 226 0.08 GLY 118 -0.05 THR 66

GLY 226 0.11 LYS 119 -0.04 THR 66

GLY 226 0.13 GLU 120 -0.04 THR 66

GLY 226 0.15 ASP 121 -0.04 THR 66

ASP 99 0.07 MET 1 -0.12 GLU 117

ASP 99 0.07 ALA 2 -0.12 GLU 117

ASP 99 0.06 LEU 3 -0.11 GLY 110

ASP 99 0.06 GLY 4 -0.10 GLY 110

ASP 99 0.06 ASP 5 -0.10 GLY 110

ASP 99 0.05 PRO 6 -0.11 GLY 110

ASP 99 0.05 ILE 7 -0.10 GLY 110

THR 435 0.05 GLN 8 -0.10 LYS 119

THR 435 0.05 VAL 9 -0.10 LYS 119

THR 435 0.05 ARG 10 -0.10 LYS 119

THR 435 0.05 LEU 11 -0.10 LYS 119

THR 435 0.04 SER 12 -0.10 GLU 117

THR 435 0.05 PRO 13 -0.13 GLY 110

THR 435 0.05 GLU 14 -0.13 GLY 110

THR 435 0.05 LYS 15 -0.12 GLY 118

THR 435 0.05 GLN 16 -0.13 LYS 119

THR 435 0.05 ALA 17 -0.15 GLY 118

THR 435 0.05 LEU 18 -0.15 ASP 67

THR 435 0.05 LEU 19 -0.15 ALA 50

THR 435 0.05 GLU 20 -0.16 LYS 119

THR 435 0.05 ASP 21 -0.18 GLY 118

THR 435 0.05 GLU 22 -0.19 ARG 53

THR 435 0.05 ALA 23 -0.17 SER 57

THR 435 0.05 ALA 24 -0.19 LYS 119

THR 435 0.05 ARG 25 -0.22 SER 57

THR 435 0.06 LYS 26 -0.20 SER 57

THR 435 0.06 GLY 27 -0.20 GLY 110

THR 435 0.05 LYS 28 -0.18 GLY 110

THR 435 0.05 ARG 29 -0.17 GLY 110

THR 435 0.05 LEU 30 -0.15 LYS 119

THR 435 0.05 ALA 31 -0.14 GLY 110

THR 435 0.05 THR 32 -0.14 GLY 110

THR 435 0.05 TYR 33 -0.14 GLY 110

THR 435 0.05 LEU 34 -0.13 GLY 46

ASP 99 0.05 ARG 35 -0.11 GLY 110

ASP 99 0.06 GLU 36 -0.12 ALA 49

ASP 99 0.05 LEU 37 -0.13 GLY 46

ASP 99 0.06 LEU 38 -0.11 GLY 46

GLY 46 0.07 GLU 39 -0.09 GLY 46

GLY 46 0.06 SER 40 -0.10 ALA 49

GLY 46 0.09 GLU 41 -0.08 GLY 46

GLY 46 0.08 ASN 42 -0.08 ALA 49

ASP 99 0.06 ASP 43 -0.12 ALA 49

ASP 99 0.06 LEU 44 -0.07 ALA 49

GLU 47 0.08 GLN 45 -0.09 SER 40

GLU 54 0.06 GLY 46 -0.10 SER 40

ASP 99 0.06 GLU 47 -0.09 ASP 43

ASP 99 0.06 LEU 48 -0.06 LEU 44

ASP 99 0.06 ALA 49 -0.06 ASP 43

VAL 56 0.06 ALA 50 -0.09 ASP 43

ASP 99 0.05 LEU 51 -0.09 GLU 14

ASP 99 0.05 ARG 52 -0.08 GLU 14

HIS 60 0.06 ARG 53 -0.09 LEU 18

ASP 99 0.05 GLU 54 -0.12 LEU 18

ARG 25 0.07 VAL 55 -0.11 LEU 18

ARG 25 0.07 VAL 56 -0.09 LEU 18

ASP 99 0.06 SER 57 -0.12 LEU 18

ARG 25 0.08 LEU 58 -0.13 LEU 18

ARG 25 0.08 HIS 59 -0.11 ASP 21

ARG 25 0.08 HIS 60 -0.11 ASP 21

ARG 25 0.07 VAL 61 -0.14 ASP 21

ARG 25 0.09 ILE 62 -0.13 ASP 21

ARG 25 0.09 GLU 63 -0.12 ARG 25

ARG 25 0.08 ASP 64 -0.13 ARG 25

ARG 25 0.09 LEU 65 -0.15 ARG 25

ASP 21 0.10 ALA 66 -0.13 ARG 25

ARG 25 0.10 ASP 67 -0.12 ARG 25

ARG 25 0.08 THR 68 -0.15 ARG 25

ARG 25 0.10 GLY 69 -0.15 ARG 25

ASP 21 0.10 LEU 70 -0.13 ARG 25

ARG 25 0.09 ARG 71 -0.14 ARG 25

ARG 25 0.09 SER 72 -0.17 ARG 25

ARG 25 0.10 ASP 73 -0.17 ARG 25

ARG 25 0.08 GLN 74 -0.18 ARG 25

ARG 25 0.07 SER 75 -0.20 ARG 25

ARG 25 0.07 GLY 76 -0.24 ARG 25

ARG 25 0.06 PRO 77 -0.27 ARG 25

ARG 25 0.07 GLY 78 -0.27 ARG 25

ARG 25 0.07 GLN 79 -0.23 ARG 25

ARG 25 0.06 ASN 80 -0.23 ARG 25

ARG 25 0.06 ALA 81 -0.25 ARG 25

ARG 25 0.07 VAL 82 -0.23 ARG 25

ARG 25 0.06 GLN 83 -0.20 ARG 25

ARG 25 0.06 ILE 84 -0.21 ARG 25

ARG 25 0.06 GLU 85 -0.22 ARG 25

ARG 25 0.07 THR 86 -0.19 ARG 25

ARG 25 0.06 LEU 87 -0.18 ARG 25

ARG 25 0.06 LEU 88 -0.20 ARG 25

ARG 25 0.06 LEU 89 -0.19 ARG 25

ARG 25 0.06 LEU 90 -0.17 ARG 25

ARG 25 0.05 ARG 91 -0.17 GLY 27

ARG 25 0.06 ALA 92 -0.18 GLY 27

ARG 25 0.06 ILE 93 -0.17 ARG 25

ALA 24 0.06 ALA 94 -0.15 GLY 27

ARG 25 0.05 GLY 95 -0.16 GLY 27

GLY 189 0.05 PRO 96 -0.17 THR 66

ARG 25 0.05 GLU 97 -0.15 THR 66

ALA 24 0.05 ARG 98 -0.14 THR 66

ARG 25 0.05 MET 99 -0.15 THR 66

ARG 25 0.04 LYS 100 -0.15 THR 66

ARG 25 0.04 PRO 101 -0.13 THR 66

ARG 25 0.04 VAL 102 -0.13 THR 66

GLY 226 0.04 LYS 103 -0.15 THR 66

GLY 226 0.05 GLY 104 -0.14 THR 66

GLY 226 0.06 GLU 105 -0.12 THR 66

GLY 226 0.05 LEU 106 -0.13 THR 66

GLY 226 0.06 LYS 107 -0.15 ASP 68

GLY 226 0.07 ARG 108 -0.12 ASP 68

GLY 226 0.08 LEU 109 -0.11 ASP 68

GLY 226 0.08 GLY 110 -0.13 ASP 68

GLY 226 0.06 ILE 111 -0.13 ASP 68

GLY 226 0.06 GLU 112 -0.16 ASP 68

GLY 226 0.05 VAL 113 -0.16 THR 66

ILE 436 0.04 TRP 114 -0.18 GLY 27

ILE 436 0.04 THR 115 -0.21 GLY 27

LEU 109 0.05 PRO 116 -0.24 GLY 27

ILE 436 0.05 GLU 117 -0.25 GLY 27

ILE 436 0.06 GLY 118 -0.22 GLY 27

ILE 436 0.06 LYS 119 -0.22 ASP 68

ILE 436 0.05 GLU 120 -0.22 ASP 68

ILE 436 0.04 ASP 121 -0.24 ASP 68

ALA 2 0.09 ASN 1 -0.06 GLU 97

ALA 2 0.09 SER 2 -0.06 GLU 97

ALA 2 0.08 VAL 3 -0.06 GLU 97

ALA 2 0.09 GLY 4 -0.06 GLU 97

ALA 2 0.08 GLN 5 -0.06 GLU 97

ALA 17 0.08 GLY 6 -0.06 GLU 97

ALA 17 0.08 GLU 7 -0.06 GLU 97

ALA 17 0.07 PHE 8 -0.06 GLU 97

ALA 17 0.07 GLY 9 -0.06 GLU 97

ALA 17 0.06 GLY 10 -0.06 GLU 97

ALA 17 0.06 ALA 11 -0.06 GLU 97

ALA 17 0.07 PRO 12 -0.06 GLU 97

ALA 17 0.07 PHE 13 -0.07 GLU 97

ALA 17 0.07 LYS 14 -0.07 GLU 97

ALA 17 0.07 ARG 15 -0.07 GLU 97

ALA 17 0.07 PHE 16 -0.07 GLU 97

ALA 17 0.07 LEU 17 -0.08 GLU 97

ALA 17 0.07 ARG 18 -0.08 GLU 97

ALA 17 0.07 GLY 19 -0.08 GLU 97

ALA 17 0.07 THR 20 -0.07 GLU 97

ALA 17 0.08 ARG 21 -0.07 GLU 97

ALA 17 0.08 ILE 22 -0.07 GLU 97

ALA 17 0.09 VAL 23 -0.06 GLU 97

ALA 2 0.09 SER 24 -0.06 GLU 97

ALA 2 0.10 GLY 25 -0.06 GLU 97

ALA 2 0.11 GLY 26 -0.06 GLU 97

ALA 2 0.10 LYS 27 -0.06 GLU 97

ALA 2 0.10 LEU 28 -0.06 GLU 97

ALA 2 0.11 LYS 29 -0.06 GLU 97

ALA 2 0.11 ARG 30 -0.07 GLU 97

ALA 2 0.11 MET 31 -0.07 GLU 97

ALA 17 0.11 THR 32 -0.07 GLU 97

ALA 2 0.12 ARG 33 -0.07 GLU 97

ALA 2 0.12 GLU 34 -0.07 GLU 97

ALA 2 0.13 LYS 35 -0.07 GLU 97

ALA 2 0.13 ALA 36 -0.07 GLU 97

MET 1 0.13 LYS 37 -0.07 GLU 97

MET 1 0.12 GLN 38 -0.07 GLU 97

MET 1 0.12 VAL 39 -0.06 GLU 97

GLU 99 0.11 THR 40 -0.06 GLU 97

GLU 14 0.10 VAL 41 -0.06 GLU 97

GLU 99 0.10 ALA 42 -0.06 GLU 97

GLU 99 0.11 GLY 43 -0.06 GLU 97

ALA 2 0.10 VAL 44 -0.06 GLU 97

ALA 2 0.11 PRO 45 -0.06 GLU 97

ALA 17 0.10 MET 46 -0.07 GLU 97

ALA 17 0.11 PRO 47 -0.07 GLU 97

ALA 17 0.11 ARG 48 -0.07 GLU 97

ALA 17 0.10 ASP 49 -0.08 GLU 97

ALA 17 0.10 ALA 50 -0.07 GLU 97

ALA 17 0.10 GLU 51 -0.07 GLU 97

ALA 17 0.09 PRO 52 -0.08 GLU 97

ALA 17 0.08 ARG 53 -0.08 GLU 97

ALA 17 0.08 HIS 54 -0.07 GLU 97

ALA 17 0.08 LEU 55 -0.06 GLU 97

ALA 17 0.07 LEU 56 -0.06 GLU 97

ALA 17 0.07 VAL 57 -0.06 GLU 97

ALA 17 0.06 ASN 58 -0.05 GLU 97

ALA 17 0.06 GLY 59 -0.05 GLU 97

ALA 17 0.06 ALA 60 -0.05 THR 66

ALA 17 0.06 THR 61 -0.04 GLU 97

GLU 99 0.07 GLY 62 -0.04 GLU 97

ALA 17 0.07 THR 63 -0.04 GLU 97

GLU 99 0.08 GLY 64 -0.05 GLU 97

GLU 14 0.08 LYS 65 -0.05 GLU 97

GLU 99 0.09 SER 66 -0.05 GLU 97

GLU 99 0.10 VAL 67 -0.05 GLU 97

GLU 99 0.09 LEU 68 -0.05 GLU 97

GLU 99 0.09 LEU 69 -0.05 GLU 97

GLU 99 0.11 ARG 70 -0.05 GLU 97

GLU 99 0.11 GLU 71 -0.05 GLU 97

GLU 99 0.11 LEU 72 -0.06 GLU 97

GLU 99 0.11 ALA 73 -0.05 GLU 97

GLU 99 0.13 TYR 74 -0.05 GLU 97

GLU 99 0.13 THR 75 -0.06 GLU 97

GLU 99 0.12 GLY 76 -0.06 GLU 97

GLU 99 0.14 LEU 77 -0.06 GLU 97

GLU 99 0.15 LEU 78 -0.06 GLU 97

GLU 99 0.14 ARG 79 -0.06 GLU 97

GLU 99 0.14 GLY 80 -0.06 GLU 97

GLU 14 0.13 ASP 81 -0.06 GLU 97

GLU 14 0.12 ARG 82 -0.06 GLU 97

GLU 14 0.11 MET 83 -0.06 GLU 97

GLU 14 0.10 VAL 84 -0.05 GLU 97

GLU 14 0.09 ILE 85 -0.05 GLU 97

ALA 17 0.08 VAL 86 -0.05 GLU 97

GLU 99 0.08 ASP 87 -0.04 GLU 97

GLU 99 0.07 PRO 88 -0.04 GLU 97

GLU 99 0.08 ASN 89 -0.03 GLU 97

GLU 99 0.10 GLY 90 -0.04 GLU 97

GLU 99 0.11 ASP 91 -0.04 GLU 97

GLU 99 0.11 MET 92 -0.04 GLU 97

GLU 99 0.12 LEU 93 -0.04 GLU 97

GLU 99 0.13 SER 94 -0.04 GLU 97

GLU 99 0.14 LYS 95 -0.04 GLU 97

GLU 99 0.14 PHE 96 -0.05 GLU 97

GLU 99 0.14 GLY 97 -0.04 GLU 97

GLU 99 0.16 ARG 98 -0.04 GLU 97

GLU 99 0.17 ASP 99 -0.04 GLU 97

GLU 99 0.16 LYS 100 -0.04 GLU 97

GLU 99 0.14 ASP 101 -0.04 GLU 97

GLU 99 0.12 ILE 102 -0.04 GLU 97

GLU 99 0.11 ILE 103 -0.04 GLU 97

GLU 99 0.09 LEU 104 -0.04 GLU 97

GLU 99 0.08 ASN 105 -0.03 GLU 97

GLU 99 0.06 PRO 106 -0.03 GLU 97

GLU 99 0.07 TYR 107 -0.03 GLU 97

GLU 99 0.10 ASP 108 -0.03 GLU 97

ASP 98 0.12 GLN 109 -0.03 GLU 97

GLU 99 0.13 ARG 110 -0.03 GLU 97

GLU 99 0.11 THR 111 -0.03 GLU 97

GLU 99 0.11 LYS 112 -0.03 GLU 97

ASP 121 0.10 GLY 113 -0.03 GLY 95

ASP 121 0.08 TRP 114 -0.03 GLY 95

SER 167 0.07 SER 115 -0.05 THR 66

ASP 21 0.06 PHE 116 -0.07 THR 66

ASP 21 0.06 PHE 117 -0.07 THR 66

ASP 21 0.08 ASN 118 -0.05 THR 66

ASP 21 0.07 GLU 119 -0.06 THR 66

ASP 21 0.07 ILE 120 -0.07 THR 66

GLU 97 0.08 ARG 121 -0.07 ALA 24

ARG 25 0.07 ASN 122 -0.09 ALA 24

ARG 25 0.06 ASP 123 -0.11 THR 66

ARG 25 0.06 TYR 124 -0.11 THR 66

ARG 25 0.06 ASP 125 -0.10 THR 66

ARG 25 0.05 TRP 126 -0.11 THR 66

ARG 25 0.05 GLN 127 -0.12 THR 66

ARG 25 0.05 ARG 128 -0.11 THR 66

ARG 25 0.05 TYR 129 -0.10 THR 66

ARG 25 0.04 ALA 130 -0.12 THR 66

ARG 25 0.04 LEU 131 -0.12 THR 66

ARG 25 0.05 SER 132 -0.10 THR 66

ARG 25 0.04 VAL 133 -0.10 THR 66

ARG 25 0.03 VAL 134 -0.12 THR 66

ARG 25 0.04 PRO 135 -0.12 THR 66

ALA 24 0.03 ARG 136 -0.13 THR 66

ALA 24 0.03 GLY 137 -0.15 THR 66

ALA 24 0.03 LYS 138 -0.15 THR 66

ALA 24 0.03 THR 139 -0.17 THR 66

ALA 24 0.03 ASP 140 -0.18 THR 66

ARG 25 0.03 GLU 141 -0.19 THR 66

ARG 25 0.03 ALA 142 -0.17 THR 66

ALA 24 0.03 GLU 143 -0.17 THR 66

ARG 25 0.03 GLU 144 -0.19 THR 66

ARG 25 0.03 TRP 145 -0.19 THR 66

ALA 24 0.03 ALA 146 -0.16 THR 66

ALA 24 0.04 SER 147 -0.17 THR 66

ARG 25 0.03 TYR 148 -0.18 THR 66

ARG 25 0.03 GLY 149 -0.16 THR 66

ALA 24 0.04 ARG 150 -0.15 THR 66

ARG 25 0.04 LEU 151 -0.16 THR 66

ARG 25 0.03 LEU 152 -0.17 THR 66

ARG 25 0.03 LEU 153 -0.14 THR 66

ALA 24 0.04 ARG 154 -0.14 THR 66

ARG 25 0.04 GLU 155 -0.15 THR 66

ARG 25 0.04 THR 156 -0.15 THR 66

ALA 24 0.04 ALA 157 -0.12 THR 66

ARG 25 0.04 LYS 158 -0.12 THR 66

ARG 25 0.04 LYS 159 -0.13 THR 66

GLY 226 0.05 LEU 160 -0.11 THR 66

ARG 25 0.05 ALA 161 -0.10 THR 66

ARG 25 0.05 LEU 162 -0.11 THR 66

GLY 226 0.05 ILE 163 -0.11 THR 66

ASP 227 0.07 GLY 164 -0.08 THR 66

GLY 226 0.08 THR 165 -0.08 THR 66

GLY 226 0.07 PRO 166 -0.08 THR 66

GLY 226 0.08 SER 167 -0.07 THR 66

SER 115 0.05 MET 168 -0.08 THR 66

VAL 221 0.06 ARG 169 -0.09 THR 66

GLY 226 0.05 GLU 170 -0.11 ASP 68

GLY 226 0.04 LEU 171 -0.12 THR 66

VAL 221 0.05 PHE 172 -0.12 ASP 68

ILE 436 0.05 HIS 173 -0.14 ASP 68

ILE 436 0.04 TRP 174 -0.16 ASP 68

ILE 436 0.03 THR 175 -0.16 ASP 68

ILE 436 0.03 THR 176 -0.17 ASP 68

ILE 436 0.05 ILE 177 -0.18 ASP 68

ILE 436 0.04 ALA 178 -0.19 ASP 68

ILE 436 0.04 THR 179 -0.23 ASP 68

ILE 436 0.03 PHE 180 -0.24 ASP 68

ILE 436 0.04 ASP 181 -0.25 ASP 68

ILE 436 0.04 ASP 182 -0.22 ASP 68

ILE 436 0.04 LEU 183 -0.20 ASP 68

ARG 25 0.03 ARG 184 -0.22 ASP 68

ILE 436 0.03 GLY 185 -0.21 ASP 68

ILE 436 0.03 PHE 186 -0.18 ASP 68

ARG 25 0.04 LEU 187 -0.19 THR 66

ARG 25 0.04 GLU 188 -0.20 THR 66

PRO 96 0.05 GLY 189 -0.19 THR 66

ARG 25 0.04 THR 190 -0.18 THR 66

ARG 25 0.04 LEU 191 -0.18 THR 66

ARG 25 0.04 ALA 192 -0.19 THR 66

ARG 25 0.04 GLU 193 -0.21 THR 66

ARG 25 0.04 SER 194 -0.22 THR 66

ARG 25 0.03 LEU 195 -0.22 THR 66

ARG 25 0.03 PHE 196 -0.24 THR 66

GLY 27 0.03 ALA 197 -0.26 THR 66

GLY 27 0.03 GLY 198 -0.28 THR 66

GLY 27 0.03 SER 199 -0.28 THR 66

GLY 27 0.03 ASN 200 -0.28 THR 66

GLY 27 0.03 GLU 201 -0.26 THR 66

ARG 25 0.03 ALA 202 -0.25 THR 66

GLY 27 0.03 SER 203 -0.25 THR 66

GLY 27 0.03 LYS 204 -0.24 THR 66

ARG 25 0.03 ALA 205 -0.22 THR 66

ARG 25 0.03 LEU 206 -0.22 THR 66

ARG 25 0.03 THR 207 -0.22 THR 66

ARG 25 0.03 SER 208 -0.20 THR 66

ARG 25 0.03 ALA 209 -0.19 THR 66

ARG 25 0.03 ARG 210 -0.18 ASP 68

ARG 25 0.03 PHE 211 -0.18 ASP 68

ARG 25 0.03 VAL 212 -0.16 THR 66

ARG 25 0.03 LEU 213 -0.15 THR 66

ARG 25 0.02 SER 214 -0.15 ASP 68

ARG 25 0.03 ASP 215 -0.13 THR 66

ARG 25 0.03 LYS 216 -0.12 THR 66

ARG 25 0.03 LEU 217 -0.11 THR 66

LYS 119 0.03 PRO 218 -0.09 THR 66

ARG 25 0.04 GLU 219 -0.07 THR 66

ARG 25 0.04 HIS 220 -0.07 THR 66

ARG 169 0.06 VAL 221 -0.07 THR 66

GLY 110 0.05 THR 222 -0.04 THR 66

ALA 17 0.05 MET 223 -0.03 THR 66

ASP 121 0.08 PRO 224 -0.03 GLY 95

ASP 121 0.12 ASP 225 -0.03 PRO 96

ASP 121 0.15 GLY 226 -0.03 GLU 97

GLU 120 0.11 ASP 227 -0.03 GLY 95

GLU 14 0.10 PHE 228 -0.04 GLY 95

ALA 17 0.09 SER 229 -0.04 GLU 97

ALA 17 0.09 ILE 230 -0.05 GLU 97

ALA 17 0.09 ARG 231 -0.06 GLU 97

ALA 17 0.11 SER 232 -0.05 GLU 97

GLU 14 0.11 TRP 233 -0.05 GLU 97

ALA 17 0.11 LEU 234 -0.06 GLU 97

ALA 17 0.12 GLU 235 -0.07 GLU 97

GLU 14 0.13 ASP 236 -0.06 GLU 97

GLU 14 0.14 PRO 237 -0.06 GLU 97

GLU 14 0.15 ASN 238 -0.06 GLU 97

GLU 99 0.14 GLY 239 -0.05 GLU 97

GLU 99 0.14 GLY 240 -0.05 GLU 97

GLU 99 0.12 ASN 241 -0.05 GLU 97

GLU 99 0.11 LEU 242 -0.05 GLU 97

GLU 99 0.10 PHE 243 -0.04 GLU 97

GLU 14 0.08 ILE 244 -0.04 GLU 97

GLU 99 0.08 THR 245 -0.04 GLU 97

GLU 99 0.07 TRP 246 -0.03 GLU 97

GLU 99 0.06 ARG 247 -0.03 GLU 97

ALA 17 0.05 GLU 248 -0.03 GLU 97

ALA 17 0.04 ASP 249 -0.03 THR 66

ASP 21 0.04 MET 250 -0.04 THR 66

ASP 21 0.04 GLY 251 -0.05 THR 66

ARG 25 0.03 PRO 252 -0.08 THR 66

ARG 25 0.03 ALA 253 -0.08 THR 66

ASP 21 0.04 LEU 254 -0.06 THR 66

ARG 25 0.04 ARG 255 -0.08 THR 66

ARG 25 0.04 PRO 256 -0.09 THR 66

ASP 21 0.05 LEU 257 -0.07 THR 66

ASP 21 0.05 ILE 258 -0.06 THR 66

ASP 21 0.05 SER 259 -0.08 THR 66

ASP 21 0.05 ALA 260 -0.08 THR 66

ASP 21 0.06 TRP 261 -0.05 THR 66

ASP 21 0.07 VAL 262 -0.06 THR 66

ASP 21 0.06 ASP 263 -0.08 THR 66

ASP 21 0.07 VAL 264 -0.06 THR 66

ASP 21 0.08 VAL 265 -0.06 GLU 97

ASP 21 0.07 CYS 266 -0.06 THR 66

ASP 21 0.07 THR 267 -0.07 THR 66

ASP 21 0.08 SER 268 -0.06 GLY 95

ASP 21 0.09 ILE 269 -0.07 GLU 97

ASP 21 0.08 LEU 270 -0.08 GLY 95

ASP 21 0.09 SER 271 -0.08 GLY 95

ASP 21 0.10 LEU 272 -0.08 GLU 97

ALA 17 0.11 PRO 273 -0.09 GLU 97

ALA 17 0.11 GLU 274 -0.09 GLU 97

ALA 17 0.12 GLU 275 -0.09 GLU 97

ALA 17 0.12 PRO 276 -0.09 GLU 97

ALA 17 0.13 LYS 277 -0.08 GLU 97

ALA 17 0.12 ARG 278 -0.08 GLU 97

ALA 17 0.12 ARG 279 -0.07 GLU 97

ALA 17 0.11 LEU 280 -0.07 GLU 97

ALA 17 0.10 TRP 281 -0.06 GLU 97

ALA 17 0.09 LEU 282 -0.06 GLU 97

ALA 17 0.08 PHE 283 -0.05 GLU 97

ALA 17 0.07 ILE 284 -0.05 GLU 97

ALA 17 0.07 ASP 285 -0.05 GLU 97

ALA 17 0.06 GLU 286 -0.05 THR 66

ASP 21 0.06 LEU 287 -0.07 THR 66

ASP 21 0.05 ALA 288 -0.08 THR 66

ASP 21 0.04 SER 289 -0.08 THR 66

ASP 21 0.05 LEU 290 -0.08 THR 66

ARG 25 0.04 GLU 291 -0.10 THR 66

ARG 25 0.04 LYS 292 -0.11 THR 66

ARG 25 0.05 LEU 293 -0.10 THR 66

ARG 25 0.05 ALA 294 -0.11 THR 66

ASP 21 0.06 SER 295 -0.09 THR 66

ASP 21 0.06 LEU 296 -0.08 THR 66

ASP 21 0.06 ALA 297 -0.09 THR 66

ASP 21 0.06 ASP 298 -0.09 THR 66

ASP 21 0.07 ALA 299 -0.08 GLU 97

ASP 21 0.07 LEU 300 -0.08 GLU 97

ASP 21 0.07 THR 301 -0.09 GLU 97

ASP 21 0.08 LYS 302 -0.09 GLU 97

ASP 21 0.08 GLY 303 -0.08 GLU 97

ALA 17 0.09 ARG 304 -0.08 GLU 97

ALA 17 0.10 LYS 305 -0.09 GLU 97

ALA 17 0.10 ALA 306 -0.08 GLU 97

ALA 17 0.11 GLY 307 -0.08 GLU 97

ALA 17 0.10 LEU 308 -0.07 GLU 97

ALA 17 0.09 ARG 309 -0.07 GLU 97

ALA 17 0.08 VAL 310 -0.06 GLU 97

ALA 17 0.08 VAL 311 -0.06 GLU 97

ALA 17 0.07 ALA 312 -0.06 GLU 97

ALA 17 0.07 GLY 313 -0.05 GLU 97

ASP 21 0.06 LEU 314 -0.06 THR 66

ASP 21 0.05 GLN 315 -0.06 THR 66

ASP 21 0.05 SER 316 -0.08 THR 66

ASP 21 0.04 THR 317 -0.09 THR 66

ARG 25 0.04 SER 318 -0.11 THR 66

ARG 25 0.04 GLN 319 -0.10 THR 66

ARG 25 0.04 LEU 320 -0.10 THR 66

ARG 25 0.04 ASP 321 -0.12 THR 66

ARG 25 0.03 ASP 322 -0.13 THR 66

ARG 25 0.03 VAL 323 -0.12 THR 66

ARG 25 0.04 TYR 324 -0.12 THR 66

ARG 25 0.03 GLY 325 -0.14 THR 66

ARG 25 0.03 VAL 326 -0.13 THR 66

ARG 25 0.04 LYS 327 -0.13 THR 66

ARG 25 0.04 GLU 328 -0.12 THR 66

ARG 25 0.04 ALA 329 -0.11 THR 66

ARG 25 0.05 GLN 330 -0.11 THR 66

ARG 25 0.05 THR 331 -0.11 THR 66

ASP 21 0.05 LEU 332 -0.10 THR 66

ASP 21 0.06 ARG 333 -0.09 THR 66

ASP 21 0.06 ALA 334 -0.09 THR 66

ASP 21 0.07 SER 335 -0.08 THR 66

ASP 21 0.07 PHE 336 -0.07 GLU 97

ALA 17 0.07 ARG 337 -0.08 GLU 97

ALA 17 0.08 SER 338 -0.07 GLU 97

ALA 17 0.07 LEU 339 -0.06 GLU 97

ALA 17 0.08 VAL 340 -0.06 GLU 97

ALA 17 0.07 VAL 341 -0.06 GLU 97

ALA 17 0.07 LEU 342 -0.05 GLU 97

ALA 17 0.06 GLY 343 -0.05 GLU 97

ALA 17 0.05 GLY 344 -0.06 THR 66

ASP 21 0.05 SER 345 -0.06 THR 66

ASP 21 0.04 ARG 346 -0.07 THR 66

ASP 21 0.04 THR 347 -0.08 THR 66

ASP 21 0.04 ASP 348 -0.09 THR 66

ASP 21 0.04 PRO 349 -0.09 THR 66

ARG 25 0.04 LYS 350 -0.10 THR 66

ASP 21 0.04 THR 351 -0.09 THR 66

ASP 21 0.05 ASN 352 -0.08 THR 66

ASP 21 0.04 GLU 353 -0.09 THR 66

ASP 21 0.05 ASP 354 -0.09 THR 66

ASP 21 0.05 MET 355 -0.08 THR 66

ASP 21 0.05 SER 356 -0.08 THR 66

ASP 21 0.05 LEU 357 -0.09 THR 66

ASP 21 0.06 SER 358 -0.08 THR 66

ALA 17 0.06 LEU 359 -0.07 GLU 97

ASP 21 0.06 GLY 360 -0.07 GLU 97

ASP 21 0.06 GLU 361 -0.08 THR 66

ALA 17 0.06 HIS 362 -0.08 GLU 97

ASP 21 0.06 GLU 363 -0.08 GLU 97

ALA 17 0.06 VAL 364 -0.08 GLU 97

ALA 17 0.06 GLU 365 -0.08 GLU 97

ALA 17 0.06 ARG 366 -0.07 GLU 97

ALA 17 0.06 ASP 367 -0.07 GLU 97

ASP 21 0.05 ARG 368 -0.08 THR 66

ALA 17 0.05 TYR 369 -0.08 THR 66

ASP 21 0.04 SER 370 -0.09 THR 66

ASP 21 0.04 LYS 371 -0.09 THR 66

ASP 21 0.04 ASN 372 -0.10 THR 66

ASP 21 0.04 THR 373 -0.10 THR 66

ALA 24 0.03 GLY 374 -0.10 THR 66

ASP 21 0.04 LYS 375 -0.10 THR 66

ASP 21 0.04 HIS 376 -0.09 THR 66

ASP 21 0.05 HIS 377 -0.08 THR 66

ASP 21 0.05 SER 378 -0.08 THR 66

ALA 17 0.05 THR 379 -0.08 THR 66

ASP 21 0.05 GLY 380 -0.08 THR 66

ALA 17 0.06 ARG 381 -0.08 THR 66

ASP 21 0.05 ALA 382 -0.08 THR 66

ALA 17 0.06 LEU 383 -0.08 THR 66

ASP 21 0.05 GLU 384 -0.09 THR 66

ASP 21 0.05 ARG 385 -0.09 THR 66

ASP 21 0.05 VAL 386 -0.09 THR 66

ASP 21 0.05 ARG 387 -0.09 THR 66

ASP 21 0.05 GLU 388 -0.08 THR 66

ASP 21 0.06 ARG 389 -0.08 THR 66

ALA 17 0.06 VAL 390 -0.07 GLU 97

ALA 17 0.06 VAL 391 -0.06 GLU 97

ASP 21 0.05 MET 392 -0.07 THR 66

ASP 21 0.05 PRO 393 -0.08 THR 66

ASP 21 0.05 ALA 394 -0.07 THR 66

ALA 17 0.06 GLU 395 -0.05 THR 66

ALA 17 0.06 ILE 396 -0.05 THR 66

ALA 17 0.05 ALA 397 -0.06 THR 66

ALA 17 0.06 ASN 398 -0.05 GLU 97

ALA 17 0.07 LEU 399 -0.05 GLU 97

ALA 17 0.07 PRO 400 -0.05 GLU 97

GLU 99 0.07 ASP 401 -0.04 GLU 97

GLU 99 0.08 LEU 402 -0.05 GLU 97

ALA 2 0.08 THR 403 -0.05 GLU 97

ALA 17 0.08 ALA 404 -0.05 GLU 97

ALA 17 0.08 TYR 405 -0.06 GLU 97

ALA 17 0.08 VAL 406 -0.06 GLU 97

ALA 17 0.08 GLY 407 -0.07 GLU 97

ALA 17 0.09 PHE 408 -0.07 GLU 97

ALA 17 0.08 ALA 409 -0.08 GLU 97

ALA 17 0.08 GLY 410 -0.08 GLU 97

ALA 17 0.08 ASN 411 -0.08 GLU 97

ALA 17 0.09 ARG 412 -0.07 GLU 97

ALA 17 0.08 PRO 413 -0.07 GLU 97

ALA 17 0.08 ILE 414 -0.07 GLU 97

ALA 17 0.08 ALA 415 -0.06 GLU 97

ALA 17 0.08 LYS 416 -0.06 GLU 97

ALA 2 0.09 VAL 417 -0.05 GLU 97

GLU 99 0.09 PRO 418 -0.05 GLU 97

GLU 99 0.10 LEU 419 -0.05 GLU 97

GLU 99 0.11 GLU 420 -0.05 GLU 97

GLU 99 0.12 ILE 421 -0.05 GLU 97

GLU 99 0.13 LYS 422 -0.05 GLU 97

GLU 99 0.14 GLN 423 -0.04 GLU 97

GLU 99 0.14 PHE 424 -0.04 GLU 97

GLU 99 0.16 ALA 425 -0.04 GLU 97

GLU 99 0.15 ASN 426 -0.04 GLU 97

GLU 99 0.17 ARG 427 -0.04 GLU 97

GLU 99 0.16 GLN 428 -0.04 GLU 97

GLU 99 0.14 PRO 429 -0.03 GLU 97

GLU 99 0.12 ALA 430 -0.03 GLU 97

GLU 99 0.11 PHE 431 -0.03 GLU 97

ASP 98 0.13 VAL 432 -0.03 GLU 97

ASP 98 0.11 GLU 433 -0.03 GLU 97

ASP 98 0.11 GLY 434 -0.03 GLU 97

ASP 98 0.10 THR 435 -0.03 GLU 97

ASP 98 0.07 ILE 436 -0.03 GLU 97

THR 435 0.04 MET 1 -0.09 GLY 110

THR 435 0.04 ALA 2 -0.10 GLY 110

THR 435 0.04 LEU 3 -0.10 LYS 119

THR 435 0.04 GLY 4 -0.12 LYS 119

THR 435 0.05 ASP 5 -0.13 LYS 119

THR 435 0.05 PRO 6 -0.12 LYS 119

THR 435 0.05 ILE 7 -0.12 LYS 119

THR 435 0.05 GLN 8 -0.12 LYS 119

THR 435 0.05 VAL 9 -0.11 GLY 110

ASP 99 0.05 ARG 10 -0.11 GLY 110

ASP 99 0.06 LEU 11 -0.10 GLY 110

ASP 99 0.06 SER 12 -0.10 GLY 110

GLY 110 0.07 PRO 13 -0.09 GLU 117

GLY 46 0.07 GLU 14 -0.08 LYS 119

GLY 46 0.07 LYS 15 -0.08 GLU 117

GLY 46 0.06 GLN 16 -0.08 GLY 110

GLY 46 0.07 ALA 17 -0.07 GLU 117

GLY 46 0.08 LEU 18 -0.06 LYS 119

GLY 46 0.07 LEU 19 -0.07 GLY 46

GLY 46 0.06 GLU 20 -0.06 GLY 110

GLY 46 0.06 ASP 21 -0.06 GLY 46

GLY 46 0.07 GLU 22 -0.06 GLY 46

GLY 46 0.06 ALA 23 -0.05 GLY 46

GLY 46 0.05 ALA 24 -0.05 GLY 46

GLY 46 0.05 ARG 25 -0.05 GLY 46

GLY 46 0.05 LYS 26 -0.04 GLY 46

ASP 99 0.05 GLY 27 -0.04 GLY 46

GLY 46 0.05 LYS 28 -0.04 GLY 110

GLY 46 0.05 ARG 29 -0.06 GLY 110

GLY 46 0.05 LEU 30 -0.06 GLY 110

ASP 99 0.05 ALA 31 -0.07 GLY 110

THR 435 0.05 THR 32 -0.06 LYS 119

GLY 46 0.05 TYR 33 -0.06 GLY 110

GLY 46 0.05 LEU 34 -0.08 GLY 46

THR 435 0.05 ARG 35 -0.08 LYS 119

THR 435 0.05 GLU 36 -0.06 LYS 119

GLY 46 0.05 LEU 37 -0.07 GLY 46

THR 435 0.05 LEU 38 -0.10 GLY 46

THR 435 0.05 GLU 39 -0.08 GLY 46

THR 435 0.05 SER 40 -0.07 GLY 46

THR 435 0.05 GLU 41 -0.12 GLY 46

THR 435 0.05 ASN 42 -0.20 GLY 46

THR 435 0.05 ASP 43 -0.08 ALA 49

THR 435 0.05 LEU 44 -0.06 GLU 41

THR 435 0.05 GLN 45 -0.19 GLY 46

THR 435 0.05 GLY 46 -0.20 ASN 42

THR 435 0.05 GLU 47 -0.12 GLN 45

THR 435 0.05 LEU 48 -0.11 GLN 45

THR 435 0.06 ALA 49 -0.17 GLU 22

ARG 25 0.06 ALA 50 -0.19 GLU 22

ARG 25 0.07 LEU 51 -0.14 ARG 25

ARG 25 0.06 ARG 52 -0.15 LYS 26

ARG 25 0.06 ARG 53 -0.21 ARG 25

ARG 25 0.08 GLU 54 -0.18 ARG 25

ARG 25 0.07 VAL 55 -0.16 ARG 25

ARG 25 0.06 VAL 56 -0.20 GLU 14

ARG 25 0.08 SER 57 -0.22 ARG 25

ARG 25 0.10 LEU 58 -0.18 GLU 14

ARG 25 0.08 HIS 59 -0.19 GLU 14

ARG 25 0.08 HIS 60 -0.23 GLU 14

ARG 25 0.10 VAL 61 -0.21 GLU 14

ARG 25 0.10 ILE 62 -0.19 LEU 18

ARG 25 0.08 GLU 63 -0.22 ASP 21

ARG 25 0.09 ASP 64 -0.25 ASP 21

ARG 25 0.10 LEU 65 -0.21 ASP 21

ARG 25 0.08 ALA 66 -0.21 ASP 21

ARG 25 0.08 ASP 67 -0.25 ASP 21

ARG 25 0.10 THR 68 -0.24 ASP 21

ARG 25 0.10 GLY 69 -0.21 ARG 25

ARG 25 0.08 LEU 70 -0.23 ARG 25

ARG 25 0.09 ARG 71 -0.25 ARG 25

LEU 70 0.11 SER 72 -0.22 ARG 25

ARG 25 0.09 ASP 73 -0.22 ARG 25

ARG 25 0.09 GLN 74 -0.25 ARG 25

ARG 25 0.10 SER 75 -0.23 ARG 25

ARG 25 0.11 GLY 76 -0.24 ARG 25

ARG 25 0.11 PRO 77 -0.26 ARG 25

ARG 25 0.12 GLY 78 -0.23 ARG 25

ARG 25 0.11 GLN 79 -0.22 ARG 25

ARG 25 0.10 ASN 80 -0.24 ARG 25

ARG 25 0.10 ALA 81 -0.24 ARG 25

ARG 25 0.11 VAL 82 -0.22 ARG 25

ARG 25 0.09 GLN 83 -0.22 ARG 25

ARG 25 0.09 ILE 84 -0.24 ARG 25

ARG 25 0.09 GLU 85 -0.23 ARG 25

ARG 25 0.09 THR 86 -0.20 ARG 25

ARG 25 0.08 LEU 87 -0.21 ARG 25

ARG 25 0.08 LEU 88 -0.22 ARG 25

ARG 25 0.09 LEU 89 -0.20 ARG 25

ARG 25 0.08 LEU 90 -0.20 ARG 25

ARG 25 0.08 ARG 91 -0.21 ARG 25

ARG 25 0.08 ALA 92 -0.21 ARG 25

ARG 25 0.08 ILE 93 -0.19 ARG 25

ARG 25 0.07 ALA 94 -0.19 ARG 25

ARG 25 0.07 GLY 95 -0.20 ALA 24

ARG 25 0.07 PRO 96 -0.22 GLY 27

ARG 25 0.06 GLU 97 -0.21 GLY 27

ARG 25 0.06 ARG 98 -0.20 GLY 27

ARG 25 0.06 MET 99 -0.22 GLY 27

ARG 25 0.06 LYS 100 -0.23 GLY 27

ARG 25 0.05 PRO 101 -0.22 GLY 27

ARG 25 0.06 VAL 102 -0.22 GLY 27

ARG 25 0.06 LYS 103 -0.25 GLY 27

ARG 25 0.05 GLY 104 -0.25 GLY 27

ARG 25 0.05 GLU 105 -0.24 GLY 27

ARG 25 0.05 LEU 106 -0.26 GLY 27

ARG 25 0.05 LYS 107 -0.28 GLY 27

ILE 436 0.04 ARG 108 -0.28 GLY 27

PRO 116 0.05 LEU 109 -0.27 GLY 27

ILE 436 0.05 GLY 110 -0.31 GLY 27

ARG 25 0.04 ILE 111 -0.29 ARG 25

ARG 25 0.05 GLU 112 -0.31 ARG 25

ARG 25 0.06 VAL 113 -0.28 ARG 25

ARG 25 0.06 TRP 114 -0.28 ARG 25

ARG 25 0.07 THR 115 -0.29 ARG 25

ARG 25 0.07 PRO 116 -0.30 ARG 25

ARG 25 0.07 GLU 117 -0.32 ARG 25

ARG 25 0.06 GLY 118 -0.33 ARG 25

ARG 25 0.06 LYS 119 -0.33 ARG 25

ARG 25 0.06 GLU 120 -0.30 GLY 27

GLY 27 0.06 ASP 121 -0.31 GLY 27

GLU 117 0.06 MET 1 -0.02 LEU 44

GLU 117 0.07 ALA 2 -0.02 GLY 46

GLY 110 0.08 LEU 3 -0.03 GLY 46

ASP 121 0.08 GLY 4 -0.03 GLY 46

ASP 121 0.09 ASP 5 -0.03 GLY 46

ASP 121 0.11 PRO 6 -0.04 GLY 46

LYS 119 0.11 ILE 7 -0.04 GLY 46

LYS 119 0.13 GLN 8 -0.04 GLY 46

LYS 119 0.13 VAL 9 -0.05 GLY 46

LYS 119 0.15 ARG 10 -0.05 GLY 46

LYS 119 0.15 LEU 11 -0.05 GLY 46

LYS 119 0.16 SER 12 -0.05 GLY 46

LYS 119 0.19 PRO 13 -0.04 GLY 46

GLY 118 0.19 GLU 14 -0.04 GLY 46

LYS 119 0.16 LYS 15 -0.04 GLY 46

LYS 119 0.17 GLN 16 -0.04 GLY 46

LYS 119 0.20 ALA 17 -0.03 GLY 46

LYS 119 0.18 LEU 18 -0.03 GLY 46

LYS 119 0.15 LEU 19 -0.03 GLY 46

LYS 119 0.18 GLU 20 -0.03 GLY 46

GLY 110 0.19 ASP 21 -0.03 GLY 46

VAL 56 0.17 GLU 22 -0.03 GLY 46

GLY 110 0.16 ALA 23 -0.02 GLY 46

GLY 110 0.19 ALA 24 -0.02 GLY 46

GLY 110 0.19 ARG 25 -0.04 GLY 46

SER 57 0.16 LYS 26 -0.04 GLY 46

GLY 110 0.18 GLY 27 -0.03 GLY 46

GLY 110 0.15 LYS 28 -0.02 GLY 46

GLY 110 0.16 ARG 29 -0.02 GLY 46

GLY 110 0.15 LEU 30 -0.03 GLY 46

GLY 110 0.13 ALA 31 -0.03 GLY 46

GLY 110 0.12 THR 32 -0.03 GLY 46

GLY 110 0.12 TYR 33 -0.03 GLY 46

GLY 110 0.11 LEU 34 -0.04 GLY 46

GLY 110 0.09 ARG 35 -0.04 GLY 46

GLY 110 0.08 GLU 36 -0.03 GLY 46

VAL 56 0.08 LEU 37 -0.04 GLY 46

LYS 119 0.07 LEU 38 -0.05 GLY 46

GLY 110 0.06 GLU 39 -0.04 LEU 44

GLY 46 0.07 SER 40 -0.04 LEU 44

GLU 47 0.05 GLU 41 -0.06 LEU 44

GLY 46 0.06 ASN 42 -0.05 LEU 44

GLY 46 0.14 ASP 43 -0.03 GLU 14

GLU 47 0.07 LEU 44 -0.03 GLU 14

LEU 37 0.04 GLN 45 -0.08 GLY 46

ASP 43 0.14 GLY 46 -0.08 GLN 45

ASP 43 0.11 GLU 47 -0.05 ARG 25

LYS 26 0.07 LEU 48 -0.07 GLU 22

LYS 26 0.10 ALA 49 -0.09 GLU 22

LYS 26 0.14 ALA 50 -0.08 GLU 22

ARG 25 0.11 LEU 51 -0.08 ARG 25

ARG 25 0.10 ARG 52 -0.11 GLU 22

ARG 25 0.13 ARG 53 -0.11 ARG 25

ARG 25 0.15 GLU 54 -0.10 ARG 25

ARG 25 0.12 VAL 55 -0.13 ARG 25

ARG 25 0.13 VAL 56 -0.16 ARG 25

ARG 25 0.17 SER 57 -0.13 ARG 25

ARG 25 0.15 LEU 58 -0.13 ARG 25

ARG 25 0.13 HIS 59 -0.17 ARG 25

ARG 25 0.15 HIS 60 -0.17 ARG 25

ARG 25 0.17 VAL 61 -0.14 ARG 25

ARG 25 0.14 ILE 62 -0.16 GLU 14

ARG 25 0.13 GLU 63 -0.18 ARG 25

ARG 25 0.16 ASP 64 -0.17 ARG 25

ARG 25 0.15 LEU 65 -0.17 ASP 21

ARG 25 0.13 ALA 66 -0.20 ASP 21

ARG 25 0.14 ASP 67 -0.20 ALA 17

ARG 25 0.16 THR 68 -0.18 ASP 21

ARG 25 0.14 GLY 69 -0.19 ASP 21

ARG 25 0.12 LEU 70 -0.22 ASP 21

ARG 25 0.14 ARG 71 -0.21 ASP 21

ARG 25 0.15 SER 72 -0.19 ASP 21

ARG 25 0.13 ASP 73 -0.22 ASP 21

ARG 25 0.14 GLN 74 -0.22 ASP 21

ARG 25 0.14 SER 75 -0.19 ASP 21

ARG 25 0.16 GLY 76 -0.18 ASP 21

ARG 25 0.16 PRO 77 -0.18 ASP 21

ARG 25 0.16 GLY 78 -0.16 ASP 21

ARG 25 0.15 GLN 79 -0.17 ASP 21

ARG 25 0.14 ASN 80 -0.19 ASP 21

ARG 25 0.15 ALA 81 -0.18 ASP 21

ARG 25 0.14 VAL 82 -0.17 ASP 21

ARG 25 0.13 GLN 83 -0.18 ARG 25

ARG 25 0.13 ILE 84 -0.19 ARG 25

ARG 25 0.13 GLU 85 -0.18 ASP 21

ARG 25 0.12 THR 86 -0.17 ARG 25

ARG 25 0.11 LEU 87 -0.19 ARG 25

ARG 25 0.12 LEU 88 -0.19 ARG 25

ARG 25 0.11 LEU 89 -0.17 ARG 25

ARG 25 0.10 LEU 90 -0.18 ARG 25

ARG 25 0.11 ARG 91 -0.19 ARG 25

ARG 25 0.11 ALA 92 -0.18 ALA 24

ARG 25 0.10 ILE 93 -0.17 ALA 24

ARG 25 0.10 ALA 94 -0.18 ALA 24

ARG 25 0.10 GLY 95 -0.19 ALA 24

ARG 25 0.10 PRO 96 -0.20 ALA 24

ARG 25 0.09 GLU 97 -0.20 ALA 24

ARG 25 0.09 ARG 98 -0.20 ALA 24

ARG 25 0.09 MET 99 -0.21 ALA 24

ARG 25 0.09 LYS 100 -0.22 ALA 24

ARG 25 0.08 PRO 101 -0.23 ALA 24

ARG 25 0.09 VAL 102 -0.23 ALA 24

ARG 25 0.09 LYS 103 -0.24 ALA 24

ARG 25 0.09 GLY 104 -0.25 ALA 24

ARG 25 0.08 GLU 105 -0.26 ALA 24

ARG 25 0.09 LEU 106 -0.26 ARG 25

ARG 25 0.09 LYS 107 -0.27 ALA 24

ARG 25 0.08 ARG 108 -0.29 ALA 24

ARG 25 0.08 LEU 109 -0.30 ARG 25

ARG 25 0.09 GLY 110 -0.30 ALA 24

ARG 25 0.09 ILE 111 -0.28 ARG 25

ARG 25 0.10 GLU 112 -0.27 ALA 24

ARG 25 0.10 VAL 113 -0.25 ALA 24

ARG 25 0.11 TRP 114 -0.24 ARG 25

ARG 25 0.12 THR 115 -0.23 ASP 21

ARG 25 0.13 PRO 116 -0.22 ASP 21

ARG 25 0.13 GLU 117 -0.23 ASP 21

ARG 25 0.12 GLY 118 -0.25 ASP 21

ARG 25 0.11 LYS 119 -0.25 ASP 21

ARG 25 0.11 GLU 120 -0.25 ALA 24

ARG 25 0.11 ASP 121 -0.24 ALA 24

GLY 110 0.19 MET 1 -0.05 GLY 46

GLU 117 0.18 ALA 2 -0.05 GLY 46

GLU 117 0.17 LEU 3 -0.05 GLY 46

LYS 119 0.18 GLY 4 -0.04 GLY 46

LYS 119 0.18 ASP 5 -0.04 GLY 46

LYS 119 0.16 PRO 6 -0.04 GLY 46

LYS 119 0.15 ILE 7 -0.04 GLY 46

LYS 119 0.13 GLN 8 -0.04 GLY 46

LYS 119 0.12 VAL 9 -0.04 GLY 46

LYS 119 0.10 ARG 10 -0.04 GLY 46

LYS 119 0.08 LEU 11 -0.04 GLY 46

LYS 119 0.06 SER 12 -0.03 GLY 46

LYS 119 0.06 PRO 13 -0.04 GLY 46

LYS 119 0.05 GLU 14 -0.04 GLY 46

LYS 119 0.06 LYS 15 -0.05 GLY 46

LYS 119 0.07 GLN 16 -0.04 GLY 46

LYS 119 0.06 ALA 17 -0.05 GLY 46

GLY 110 0.05 LEU 18 -0.06 GLY 46

GLY 110 0.07 LEU 19 -0.06 GLY 46

GLY 110 0.07 GLU 20 -0.05 GLY 46

LYS 119 0.06 ASP 21 -0.06 GLY 46

LYS 119 0.07 GLU 22 -0.06 GLY 46

GLY 110 0.08 ALA 23 -0.06 GLY 46

LYS 119 0.08 ALA 24 -0.06 GLY 46

LYS 119 0.07 ARG 25 -0.06 GLY 46

LYS 119 0.08 LYS 26 -0.06 GLY 46

LYS 119 0.09 GLY 27 -0.06 GLY 46

GLY 110 0.09 LYS 28 -0.07 GLY 46

GLY 110 0.10 ARG 29 -0.06 GLY 46

LYS 119 0.09 LEU 30 -0.06 GLY 46

LYS 119 0.11 ALA 31 -0.06 GLY 46

GLU 117 0.11 THR 32 -0.06 GLY 46

GLY 110 0.09 TYR 33 -0.07 GLY 46

LYS 119 0.10 LEU 34 -0.06 GLY 46

LYS 119 0.12 ARG 35 -0.07 GLY 46

GLY 110 0.11 GLU 36 -0.08 GLY 46

GLU 117 0.08 LEU 37 -0.09 GLY 46

LYS 119 0.10 LEU 38 -0.07 GLY 46

LYS 119 0.11 GLU 39 -0.08 GLY 46

GLY 46 0.12 SER 40 -0.10 GLY 46

GLY 46 0.12 GLU 41 -0.08 GLY 46

GLY 46 0.21 ASN 42 -0.06 GLY 46

GLY 46 0.22 ASP 43 -0.08 GLY 46

GLY 46 0.11 LEU 44 -0.07 GLY 46

ALA 49 0.12 GLN 45 -0.02 ASP 21

ASP 43 0.22 GLY 46 -0.04 ARG 25

GLN 45 0.08 GLU 47 -0.03 GLY 118

GLN 45 0.11 LEU 48 -0.04 GLU 14

ASN 42 0.13 ALA 49 -0.04 ASP 21

LYS 26 0.10 ALA 50 -0.04 ASP 21

LEU 18 0.08 LEU 51 -0.06 GLU 14

GLU 22 0.12 ARG 52 -0.06 GLU 14

LEU 18 0.15 ARG 53 -0.06 ASP 21

SER 57 0.11 GLU 54 -0.07 LEU 18

ARG 25 0.12 VAL 55 -0.08 GLU 14

ARG 25 0.18 VAL 56 -0.07 ASP 21

LEU 18 0.16 SER 57 -0.08 ASP 21

ARG 25 0.13 LEU 58 -0.10 ASP 21

ARG 25 0.17 HIS 59 -0.10 GLU 14

ARG 25 0.18 HIS 60 -0.09 ASP 21

ASP 21 0.15 VAL 61 -0.10 ASP 21

ARG 25 0.15 ILE 62 -0.12 ASP 21

ARG 25 0.18 GLU 63 -0.11 ASP 21

ASP 21 0.18 ASP 64 -0.10 ASP 21

ARG 25 0.15 LEU 65 -0.13 ASP 21

ARG 25 0.17 ALA 66 -0.14 ASP 21

ARG 25 0.19 ASP 67 -0.12 ASP 21

ARG 25 0.16 THR 68 -0.12 ASP 21

ARG 25 0.15 GLY 69 -0.15 ASP 21

ARG 25 0.16 LEU 70 -0.15 ASP 21

ARG 25 0.16 ARG 71 -0.13 ASP 21

ARG 25 0.14 SER 72 -0.14 ASP 21

ARG 25 0.14 ASP 73 -0.16 ASP 21

ARG 25 0.16 GLN 74 -0.14 ASP 21

ASP 21 0.15 SER 75 -0.14 ASP 21

ASP 21 0.16 GLY 76 -0.11 ASP 21

ASP 21 0.17 PRO 77 -0.11 ASP 21

ARG 25 0.16 GLY 78 -0.10 ASP 21

ARG 25 0.14 GLN 79 -0.11 ARG 25

ASP 21 0.15 ASN 80 -0.13 ASP 21

ASP 21 0.15 ALA 81 -0.12 ASP 21

ASP 21 0.14 VAL 82 -0.12 ARG 25

ASP 21 0.13 GLN 83 -0.14 ARG 25

ASP 21 0.14 ILE 84 -0.14 ASP 21

ASP 21 0.14 GLU 85 -0.12 ASP 21

ASP 21 0.12 THR 86 -0.13 ARG 25

ASP 21 0.13 LEU 87 -0.15 ARG 25

ASP 21 0.13 LEU 88 -0.14 ASP 21

ASP 21 0.12 LEU 89 -0.13 ARG 25

ASP 21 0.12 LEU 90 -0.14 ARG 25

ALA 24 0.12 ARG 91 -0.14 ARG 25

ASP 21 0.12 ALA 92 -0.13 ARG 25

ASP 21 0.11 ILE 93 -0.14 ARG 25

ALA 24 0.11 ALA 94 -0.15 ARG 25

ALA 24 0.12 GLY 95 -0.14 ALA 24

ALA 24 0.13 PRO 96 -0.14 ALA 24

ALA 24 0.12 GLU 97 -0.15 ALA 24

ALA 24 0.12 ARG 98 -0.16 ALA 24

ALA 24 0.13 MET 99 -0.16 ALA 24

ALA 24 0.13 LYS 100 -0.16 ALA 24

ARG 25 0.12 PRO 101 -0.18 ALA 24

ARG 25 0.13 VAL 102 -0.18 ALA 24

ARG 25 0.14 LYS 103 -0.17 ASP 21

ARG 25 0.13 GLY 104 -0.18 ASP 21

ARG 25 0.13 GLU 105 -0.19 ASP 21

ARG 25 0.14 LEU 106 -0.19 ASP 21

ARG 25 0.15 LYS 107 -0.18 ASP 21

ARG 25 0.14 ARG 108 -0.20 ASP 21

ARG 25 0.14 LEU 109 -0.21 ASP 21

ARG 25 0.15 GLY 110 -0.20 ASP 21

ARG 25 0.15 ILE 111 -0.19 ASP 21

ARG 25 0.16 GLU 112 -0.18 ASP 21

ARG 25 0.15 VAL 113 -0.17 ASP 21

ARG 25 0.16 TRP 114 -0.16 ASP 21

ARG 25 0.16 THR 115 -0.15 ASP 21

ALA 24 0.17 PRO 116 -0.13 ASP 21

ALA 24 0.18 GLU 117 -0.14 ASP 21

ARG 25 0.18 GLY 118 -0.15 ASP 21

ARG 25 0.18 LYS 119 -0.15 ASP 21

ALA 24 0.17 GLU 120 -0.15 ASP 21

ALA 24 0.17 ASP 121 -0.14 ASP 21

ASP 99 0.15 MET 1 -0.15 GLY 110

ASP 99 0.15 ALA 2 -0.15 LYS 119

ASP 99 0.14 LEU 3 -0.16 LYS 119

ASP 99 0.14 THR 4 -0.15 LYS 119

ASP 99 0.13 LYS 5 -0.15 LYS 119

ASP 99 0.13 ALA 6 -0.14 LYS 119

ASP 99 0.13 GLU 7 -0.15 LYS 119

ASP 99 0.12 MET 8 -0.16 LYS 119

ASP 99 0.12 SER 9 -0.15 LYS 119

GLY 110 0.13 GLU 10 -0.15 LYS 119

ASP 99 0.12 TYR 11 -0.16 LYS 119

ASP 99 0.11 LEU 12 -0.16 LYS 119

GLY 110 0.12 PHE 13 -0.15 LYS 119

GLY 110 0.12 ASP 14 -0.15 LYS 119

ASP 99 0.11 LYS 15 -0.17 LYS 119

ASP 99 0.11 LEU 16 -0.17 LYS 119

GLY 110 0.11 GLY 17 -0.16 LYS 119

GLY 110 0.11 LEU 18 -0.15 LYS 119

GLY 110 0.12 SER 19 -0.14 LYS 119

GLY 110 0.12 LYS 20 -0.14 LYS 119

GLY 110 0.12 ARG 21 -0.14 LYS 119

ASP 99 0.11 ASP 22 -0.15 LYS 119

ASP 99 0.11 ALA 23 -0.15 LYS 119

ASP 99 0.12 LYS 24 -0.15 LYS 119

ASP 99 0.11 GLU 25 -0.15 LYS 119

ASP 99 0.11 LEU 26 -0.16 LYS 119

ASP 99 0.12 VAL 27 -0.16 LYS 119

ASP 99 0.12 GLU 28 -0.16 ASP 121

ASP 99 0.11 LEU 29 -0.17 ASP 121

ASP 99 0.11 PHE 30 -0.18 ASP 121

ASP 99 0.11 PHE 31 -0.17 ASP 121

ASP 99 0.11 GLU 32 -0.17 ASP 121

ASP 99 0.10 GLU 33 -0.18 ASP 121

ASP 99 0.11 ILE 34 -0.18 ASP 121

ASP 99 0.11 ARG 35 -0.18 ASP 121

ARG 427 0.10 ARG 36 -0.18 ASP 121

ARG 427 0.10 ALA 37 -0.19 ASP 121

ARG 427 0.10 LEU 38 -0.19 ASP 121

ARG 427 0.10 GLU 39 -0.18 ASP 121

ARG 427 0.10 ASN 40 -0.18 ASP 121

ARG 427 0.10 GLY 41 -0.19 ASP 121

ARG 427 0.10 GLU 42 -0.20 ASP 121

ARG 427 0.10 GLN 43 -0.21 ASP 121

ARG 427 0.10 VAL 44 -0.20 ASP 121

ARG 427 0.09 LYS 45 -0.22 ASP 121

ARG 427 0.10 LEU 46 -0.21 ASP 121

ARG 427 0.09 SER 47 -0.23 ASP 121

ARG 427 0.10 GLY 48 -0.23 ASP 121

ASP 99 0.10 PHE 49 -0.22 ASP 121

ARG 427 0.10 GLY 50 -0.22 ASP 121

ARG 427 0.10 ASN 51 -0.21 ASP 121

ARG 427 0.11 PHE 52 -0.20 ASP 121

ARG 427 0.10 ASP 53 -0.20 ASP 121

ARG 427 0.10 LEU 54 -0.20 ASP 121

ARG 427 0.11 ARG 55 -0.20 ASP 121

ARG 427 0.11 ASP 56 -0.19 ASP 121

ARG 427 0.11 LYS 57 -0.19 ASP 121

ARG 427 0.11 ASN 58 -0.18 ASP 121

ARG 427 0.12 GLN 59 -0.18 ASP 121

ARG 427 0.12 ARG 60 -0.18 ASP 121

ARG 427 0.13 PRO 61 -0.17 ASP 121

ARG 427 0.13 GLY 62 -0.16 ASP 121

ARG 427 0.14 ARG 63 -0.16 ASN 200

ARG 427 0.14 ASN 64 -0.15 ASN 200

ARG 427 0.15 PRO 65 -0.15 ASN 200

ARG 427 0.16 LYS 66 -0.14 ASN 200

ARG 427 0.15 THR 67 -0.14 ASN 200

ARG 427 0.15 GLY 68 -0.15 ASN 200

ARG 427 0.14 GLU 69 -0.15 ASN 200

ARG 427 0.14 ASP 70 -0.16 ASN 200

ARG 427 0.13 ILE 71 -0.16 ASP 121

ARG 427 0.13 PRO 72 -0.16 ASP 121

ARG 427 0.12 ILE 73 -0.17 ASP 121

ARG 427 0.12 THR 74 -0.17 ASP 121

ARG 427 0.11 ALA 75 -0.18 ASP 121

ARG 427 0.11 ARG 76 -0.18 ASP 121

ARG 427 0.11 ARG 77 -0.18 ASP 121

ARG 427 0.11 VAL 78 -0.18 ASP 121

ARG 427 0.11 VAL 79 -0.19 ASP 121

ARG 427 0.11 THR 80 -0.19 ASP 121

ARG 427 0.11 PHE 81 -0.20 ASP 121

ARG 427 0.11 ARG 82 -0.21 ASP 121

ARG 427 0.11 PRO 83 -0.22 ASP 121

ARG 427 0.10 GLY 84 -0.23 ASP 121

ARG 427 0.10 GLN 85 -0.24 ASP 121

ARG 427 0.10 LYS 86 -0.24 ASP 121

ASP 99 0.11 LEU 87 -0.22 ASP 121

ARG 427 0.11 LYS 88 -0.22 ASP 121

ARG 427 0.11 SER 89 -0.23 ASP 121

ASP 99 0.11 ARG 90 -0.22 LYS 119

ASP 99 0.12 VAL 91 -0.21 ASP 121

ASP 99 0.12 GLU 92 -0.22 ASP 121

ASP 99 0.13 ASN 93 -0.22 GLY 110

ASP 99 0.13 ALA 94 -0.20 GLY 110

ASP 99 0.15 SER 95 -0.19 GLY 110

ASP 99 0.15 PRO 96 -0.18 GLY 110

ASP 99 0.16 LYS 97 -0.16 GLY 110

ASP 99 0.17 ASP 98 -0.15 GLY 110

ASP 99 0.17 GLU 99 -0.14 GLY 110

ARG 427 0.09 MET 1 -0.21 ASP 121

ARG 427 0.09 THR 2 -0.22 ASP 121

ARG 427 0.09 LYS 3 -0.21 ASP 121

ARG 427 0.09 SER 4 -0.21 ASP 121

ARG 427 0.09 GLU 5 -0.21 ASP 121

ASP 99 0.09 LEU 6 -0.20 ASP 121

ASP 99 0.09 ILE 7 -0.20 ASP 121

ASP 99 0.09 GLU 8 -0.20 ASP 121

ASP 99 0.09 ARG 9 -0.19 ASP 121

ASP 99 0.10 LEU 10 -0.18 ASP 121

ASP 99 0.09 ALA 11 -0.18 ASP 121

ASP 99 0.09 THR 12 -0.18 ASP 121

ASP 99 0.10 GLN 13 -0.17 ASP 121

ASP 99 0.10 GLN 14 -0.16 ASP 121

ASP 99 0.09 SER 15 -0.17 ASP 121

ASP 99 0.09 HIS 16 -0.16 LYS 119

ASP 99 0.09 ILE 17 -0.16 LYS 119

ASP 99 0.09 PRO 18 -0.18 LYS 119

ASP 99 0.09 ALA 19 -0.18 LYS 119

ASP 99 0.09 LYS 20 -0.19 LYS 119

ASP 99 0.09 THR 21 -0.18 LYS 119

ASP 99 0.10 VAL 22 -0.18 LYS 119

ASP 99 0.09 GLU 23 -0.20 LYS 119

ASP 99 0.10 ASP 24 -0.19 LYS 119

ASP 99 0.10 ALA 25 -0.18 LYS 119

ASP 99 0.10 VAL 26 -0.19 LYS 119

ASP 99 0.10 LYS 27 -0.20 LYS 119

ASP 99 0.11 GLU 28 -0.19 LYS 119

ASP 99 0.11 MET 29 -0.18 LYS 119

ASP 99 0.11 LEU 30 -0.20 LYS 119

ASP 99 0.11 GLU 31 -0.20 LYS 119

ASP 99 0.12 HIS 32 -0.18 LYS 119

ASP 99 0.12 MET 33 -0.18 LYS 119

ASP 99 0.12 ALA 34 -0.20 LYS 119

ASP 99 0.12 SER 35 -0.19 LYS 119

ASP 99 0.13 THR 36 -0.18 LYS 119

ASP 99 0.13 LEU 37 -0.19 LYS 119

ASP 99 0.13 ALA 38 -0.20 GLY 110

ASP 99 0.14 GLN 39 -0.18 GLY 110

ASP 99 0.14 GLY 40 -0.18 GLY 110

ASP 99 0.14 GLU 41 -0.17 GLY 110

ASP 99 0.14 ARG 42 -0.17 ASP 121

ASP 99 0.13 ILE 43 -0.17 ASP 121

ASP 99 0.14 GLU 44 -0.16 ASP 121

ASP 99 0.13 ILE 45 -0.16 ASP 121

ASP 99 0.13 ARG 46 -0.15 ASP 121

ASP 99 0.13 GLY 47 -0.16 ASP 121

ASP 99 0.12 PHE 48 -0.17 ASP 121

ASP 99 0.13 GLY 49 -0.17 ASP 121

ASP 99 0.13 SER 50 -0.17 ASP 121

ASP 99 0.13 PHE 51 -0.18 ASP 121

ASP 99 0.14 SER 52 -0.18 ASP 121

ASP 99 0.14 LEU 53 -0.18 ASP 121

ASP 99 0.14 HIS 54 -0.19 ASP 121

ARG 427 0.14 TYR 55 -0.19 ASP 121

ARG 427 0.13 ARG 56 -0.20 ASP 121

ARG 427 0.14 ALA 57 -0.20 GLY 198

ARG 427 0.13 PRO 58 -0.22 GLY 198

ARG 427 0.13 ARG 59 -0.23 GLY 198

ARG 427 0.12 THR 60 -0.24 GLY 198

ARG 427 0.11 GLY 61 -0.24 GLY 198

ARG 427 0.10 ARG 62 -0.25 ASN 200

ARG 427 0.09 ASN 63 -0.26 SER 199

ARG 427 0.09 PRO 64 -0.26 ASP 121

ARG 427 0.08 LYS 65 -0.27 ASP 121

ARG 427 0.08 THR 66 -0.28 SER 199

ARG 427 0.09 GLY 67 -0.27 ASN 200

ARG 427 0.09 ASP 68 -0.28 ASN 200

ARG 427 0.10 LYS 69 -0.27 ASN 200

ARG 427 0.10 VAL 70 -0.26 GLY 198

ARG 427 0.11 GLU 71 -0.25 GLY 198

ARG 427 0.12 LEU 72 -0.24 GLY 198

ARG 427 0.12 GLU 73 -0.23 GLY 198

ARG 427 0.13 GLY 74 -0.21 GLY 198

ARG 427 0.13 LYS 75 -0.21 ASP 121

ASP 99 0.13 TYR 76 -0.20 ASP 121

ARG 427 0.12 VAL 77 -0.20 ASP 121

ASP 99 0.12 PRO 78 -0.20 ASP 121

ARG 427 0.13 HIS 79 -0.19 ASP 121

ASP 99 0.12 PHE 80 -0.18 ASP 121

ASP 99 0.13 LYS 81 -0.17 ASP 121

ASP 99 0.12 PRO 82 -0.17 ASP 121

ASP 99 0.13 GLY 83 -0.16 ASP 121

ASP 99 0.13 LYS 84 -0.16 ASP 121

ASP 99 0.12 GLU 85 -0.16 ASP 121

ASP 99 0.12 LEU 86 -0.17 ASP 121

ARG 427 0.12 ARG 87 -0.17 ASP 121

ARG 427 0.12 ASP 88 -0.16 ASP 121

ARG 427 0.11 ARG 89 -0.17 ASP 121

ARG 427 0.11 ALA 90 -0.18 ASP 121

ARG 427 0.11 ASN 91 -0.17 ASP 121

ARG 427 0.11 ILE 92 -0.17 ASP 121

ARG 427 0.11 TYR 93 -0.17 ASP 121

ARG 427 0.11 GLY 94 -0.16 ASP 121

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** ***

CA distance fluctuations for 260211153256928911

--- normal mode 9 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* *