Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* doused_J6172_17 *

CA strain for 2602182336223344808

--- normal mode 7 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
SER 5 ARG 6 0.0000

ARG 6 GLU 7 -0.0000

GLU 7 GLU 8 0.0002

GLU 8 VAL 9 0.0001

VAL 9 GLU 10 -0.0000

GLU 10 SER 11 0.0002

SER 11 LEU 12 0.0001

LEU 12 ILE 13 0.0001

ILE 13 GLN 14 0.0004

GLN 14 GLU 15 -0.0002

GLU 15 VAL 16 -0.0003

VAL 16 LEU 17 0.0002

LEU 17 GLU 18 -0.0026

GLU 18 VAL 19 0.0001

VAL 19 TYR 20 -0.0000

TYR 20 PRO 21 0.0001

PRO 21 GLU 22 -0.0002

GLU 22 LYS 23 0.0002

LYS 23 ALA 24 0.0003

ALA 24 ARG 25 -0.0002

ARG 25 LYS 26 0.0002

LYS 26 ASP 27 0.0000

ASP 27 ARG 28 -0.0002

ARG 28 ASN 29 0.0001

ASN 29 LYS 30 -0.0000

LYS 30 HIS 31 0.0010

HIS 31 LEU 32 0.0000

LEU 32 ALA 33 -0.0000

ALA 33 VAL 34 -0.0001

VAL 34 ASN 35 0.0003

ASN 35 ASP 36 -0.0002

ASP 36 PRO 37 0.0002

PRO 37 ALA 38 0.0005

ALA 38 VAL 39 -0.0003

VAL 39 THR 40 0.0001

THR 40 GLN 41 0.0003

GLN 41 SER 42 0.0000

SER 42 LYS 43 0.0001

LYS 43 LYS 44 0.0079

LYS 44 CYS 45 -0.0004

CYS 45 ILE 46 -0.0002

ILE 46 ILE 47 -0.0004

ILE 47 SER 48 0.0000

SER 48 ASN 49 0.0002

ASN 49 LYS 50 0.0003

LYS 50 LYS 51 0.0001

LYS 51 SER 52 -0.0003

SER 52 GLN 53 0.0001

GLN 53 PRO 54 0.0001

PRO 54 GLY 55 0.0002

GLY 55 LEU 56 -0.0001

LEU 56 MET 57 -0.0044

MET 57 THR 58 0.0001

THR 58 ILE 59 -0.0000

ILE 59 ARG 60 -0.0002

ARG 60 GLY 61 0.0001

GLY 61 CYS 62 -0.0001

CYS 62 ALA 63 0.0001

ALA 63 TYR 64 -0.0001

TYR 64 ALA 65 -0.0004

ALA 65 GLY 66 -0.0001

GLY 66 SER 67 -0.0001

SER 67 LYS 68 0.0004

LYS 68 GLY 69 0.0000

GLY 69 VAL 70 -0.0026

VAL 70 VAL 71 0.0002

VAL 71 TRP 72 0.0003

TRP 72 GLY 73 0.0001

GLY 73 PRO 74 -0.0001

PRO 74 ILE 75 0.0004

ILE 75 LYS 76 -0.0001

LYS 76 ASP 77 -0.0001

ASP 77 MET 78 -0.0000

MET 78 ILE 79 -0.0003

ILE 79 HIS 80 -0.0003

HIS 80 ILE 81 -0.0001

ILE 81 SER 82 0.0001

SER 82 HIS 83 -0.0039

HIS 83 GLY 84 -0.0000

GLY 84 PRO 85 0.0001

PRO 85 VAL 86 -0.0003

VAL 86 GLY 87 -0.0004

GLY 87 CYS 88 0.0001

CYS 88 GLY 89 0.0001

GLY 89 GLN 90 -0.0001

GLN 90 TYR 91 -0.0001

TYR 91 SER 92 0.0001

SER 92 ARG 93 0.0001

ARG 93 ALA 94 0.0001

ALA 94 GLY 95 0.0004

GLY 95 ARG 96 0.0133

ARG 96 ARG 97 0.0005

ARG 97 ASN 98 -0.0005

ASN 98 TYR 99 -0.0002

TYR 99 TYR 100 -0.0001

TYR 100 ILE 101 0.0002

ILE 101 GLY 102 0.0001

GLY 102 THR 103 -0.0002

THR 103 THR 104 -0.0000

THR 104 GLY 105 -0.0003

GLY 105 VAL 106 -0.0002

VAL 106 ASN 107 -0.0003

ASN 107 ALA 108 -0.0000

ALA 108 PHE 109 0.0151

PHE 109 VAL 110 -0.0002

VAL 110 THR 111 -0.0001

THR 111 MET 112 -0.0002

MET 112 ASN 113 0.0000

ASN 113 PHE 114 0.0005

PHE 114 THR 115 -0.0001

THR 115 SER 116 0.0002

SER 116 ASP 117 0.0001

ASP 117 PHE 118 0.0001

PHE 118 GLN 119 0.0004

GLN 119 GLU 120 -0.0001

GLU 120 LYS 121 0.0003

LYS 121 ASP 122 -0.0011

ASP 122 ILE 123 -0.0002

ILE 123 VAL 124 -0.0000

VAL 124 PHE 125 0.0002

PHE 125 GLY 126 0.0003

GLY 126 GLY 127 -0.0002

GLY 127 ASP 128 -0.0000

ASP 128 LYS 129 -0.0002

LYS 129 LYS 130 -0.0005

LYS 130 LEU 131 0.0002

LEU 131 ALA 132 -0.0001

ALA 132 LYS 133 -0.0001

LYS 133 LEU 134 0.0001

LEU 134 ILE 135 0.0193

ILE 135 ASP 136 0.0001

ASP 136 GLU 137 0.0003

GLU 137 VAL 138 -0.0003

VAL 138 GLU 139 -0.0001

GLU 139 THR 140 -0.0003

THR 140 LEU 141 0.0004

LEU 141 PHE 142 -0.0000

PHE 142 PRO 143 0.0001

PRO 143 LEU 144 -0.0002

LEU 144 ASN 145 -0.0000

ASN 145 LYS 146 -0.0002

LYS 146 GLY 147 -0.0002

GLY 147 ILE 148 -0.0000

ILE 148 SER 149 -0.0002

SER 149 VAL 150 -0.0000

VAL 150 GLN 151 -0.0001

GLN 151 SER 152 0.0003

SER 152 GLU 153 0.0001

GLU 153 CYS 154 0.0001

CYS 154 PRO 155 -0.0000

PRO 155 ILE 156 0.0001

ILE 156 GLY 157 0.0000

GLY 157 LEU 158 0.0006

LEU 158 ILE 159 -0.0002

ILE 159 GLY 160 0.0002

GLY 160 ASP 161 0.0004

ASP 161 ASP 162 0.0002

ASP 162 ILE 163 -0.0002

ILE 163 GLU 164 0.0002

GLU 164 SER 165 0.0001

SER 165 VAL 166 -0.0001

VAL 166 SER 167 0.0001

SER 167 LYS 168 0.0001

LYS 168 VAL 169 0.0004

VAL 169 LYS 170 -0.0002

LYS 170 GLY 171 -0.0002

GLY 171 ALA 172 0.0002

ALA 172 GLU 173 0.0002

GLU 173 LEU 174 0.0031

LEU 174 SER 175 -0.0004

SER 175 LYS 176 -0.0001

LYS 176 THR 177 -0.0001

THR 177 ILE 178 0.0001

ILE 178 VAL 179 0.0001

VAL 179 PRO 180 0.0001

PRO 180 VAL 181 0.0003

VAL 181 ARG 182 -0.0002

ARG 182 CYS 183 0.0002

CYS 183 GLU 184 -0.0001

GLU 184 GLY 185 -0.0001

GLY 185 PHE 186 0.0001

PHE 186 ARG 187 -0.0220

ARG 187 GLY 188 -0.0000

GLY 188 VAL 189 0.0003

VAL 189 SER 190 -0.0003

SER 190 GLN 191 0.0002

GLN 191 SER 192 0.0003

SER 192 LEU 193 0.0000

LEU 193 GLY 194 -0.0002

GLY 194 HIS 195 -0.0001

HIS 195 HIS 196 -0.0000

HIS 196 ILE 197 0.0002

ILE 197 ALA 198 -0.0003

ALA 198 ASN 199 -0.0001

ASN 199 ASP 200 0.0054

ASP 200 ALA 201 0.0002

ALA 201 VAL 202 -0.0001

VAL 202 ARG 203 0.0003

ARG 203 ASP 204 0.0004

ASP 204 TRP 205 -0.0004

TRP 205 VAL 206 0.0001

VAL 206 LEU 207 -0.0002

LEU 207 GLY 208 0.0003

GLY 208 LYS 209 0.0001

LYS 209 ARG 210 0.0001

ARG 210 ASP 211 -0.0001

ASP 211 GLU 212 0.0000

GLU 212 ASP 213 0.0010

ASP 213 THR 214 0.0000

THR 214 THR 215 -0.0000

THR 215 PHE 216 -0.0003

PHE 216 ALA 217 0.0002

ALA 217 SER 218 -0.0001

SER 218 THR 219 -0.0002

THR 219 PRO 220 0.0001

PRO 220 TYR 221 -0.0002

TYR 221 ASP 222 -0.0002

ASP 222 VAL 223 0.0005

VAL 223 ALA 224 -0.0001

ALA 224 ILE 225 0.0003

ILE 225 ILE 226 -0.0015

ILE 226 GLY 227 0.0005

GLY 227 ASP 228 0.0001

ASP 228 TYR 229 0.0003

TYR 229 ASN 230 0.0004

ASN 230 ILE 231 -0.0003

ILE 231 GLY 232 0.0002

GLY 232 GLY 233 0.0001

GLY 233 ASP 234 0.0004

ASP 234 ALA 235 -0.0001

ALA 235 TRP 236 -0.0000

TRP 236 SER 237 0.0002

SER 237 SER 238 0.0002

SER 238 ARG 239 0.0016

ARG 239 ILE 240 -0.0002

ILE 240 LEU 241 -0.0002

LEU 241 LEU 242 0.0002

LEU 242 GLU 243 0.0004

GLU 243 GLU 244 -0.0001

GLU 244 MET 245 0.0001

MET 245 GLY 246 -0.0000

GLY 246 LEU 247 -0.0002

LEU 247 ARG 248 -0.0001

ARG 248 CYS 249 0.0000

CYS 249 VAL 250 -0.0002

VAL 250 ALA 251 0.0003

ALA 251 GLN 252 -0.0011

GLN 252 TRP 253 0.0002

TRP 253 SER 254 -0.0004

SER 254 GLY 255 0.0004

GLY 255 ASP 256 0.0001

ASP 256 GLY 257 0.0002

GLY 257 SER 258 -0.0002

SER 258 ILE 259 -0.0004

ILE 259 SER 260 0.0001

SER 260 GLU 261 0.0002

GLU 261 ILE 262 -0.0000

ILE 262 GLU 263 0.0002

GLU 263 LEU 264 0.0000

LEU 264 THR 265 0.0026

THR 265 PRO 266 -0.0002

PRO 266 LYS 267 0.0004

LYS 267 VAL 268 0.0000

VAL 268 LYS 269 0.0002

LYS 269 LEU 270 -0.0001

LEU 270 ASN 271 -0.0003

ASN 271 LEU 272 0.0003

LEU 272 VAL 273 0.0002

VAL 273 HIS 274 -0.0005

HIS 274 CYS 275 0.0002

CYS 275 TYR 276 -0.0001

TYR 276 ARG 277 -0.0001

ARG 277 SER 278 -0.0007

SER 278 MET 279 0.0001

MET 279 ASN 280 0.0001

ASN 280 TYR 281 -0.0001

TYR 281 ILE 282 0.0000

ILE 282 SER 283 0.0001

SER 283 ARG 284 0.0001

ARG 284 HIS 285 -0.0000

HIS 285 MET 286 0.0003

MET 286 GLU 287 0.0001

GLU 287 GLU 288 -0.0000

GLU 288 LYS 289 -0.0004

LYS 289 TYR 290 0.0000

TYR 290 GLY 291 -0.0031

GLY 291 ILE 292 0.0004

ILE 292 PRO 293 0.0000

PRO 293 TRP 294 0.0001

TRP 294 MET 295 -0.0000

MET 295 GLU 296 0.0001

GLU 296 TYR 297 -0.0003

TYR 297 ASN 298 0.0005

ASN 298 PHE 299 -0.0003

PHE 299 PHE 300 0.0005

PHE 300 GLY 301 -0.0002

GLY 301 PRO 302 -0.0001

PRO 302 THR 303 0.0001

THR 303 LYS 304 0.0013

LYS 304 THR 305 0.0003

THR 305 ILE 306 0.0002

ILE 306 GLU 307 -0.0003

GLU 307 SER 308 -0.0001

SER 308 LEU 309 0.0004

LEU 309 ARG 310 -0.0001

ARG 310 ALA 311 0.0000

ALA 311 ILE 312 -0.0002

ILE 312 ALA 313 -0.0003

ALA 313 ALA 314 0.0001

ALA 314 LYS 315 -0.0002

LYS 315 PHE 316 0.0000

PHE 316 ASP 317 0.0001

ASP 317 GLU 318 0.0003

GLU 318 SER 319 0.0002

SER 319 ILE 320 -0.0002

ILE 320 GLN 321 -0.0004

GLN 321 LYS 322 -0.0001

LYS 322 LYS 323 0.0001

LYS 323 CYS 324 -0.0000

CYS 324 GLU 325 0.0001

GLU 325 GLU 326 -0.0001

GLU 326 VAL 327 0.0004

VAL 327 ILE 328 0.0001

ILE 328 ALA 329 0.0002

ALA 329 LYS 330 -0.0020

LYS 330 TYR 331 -0.0002

TYR 331 LYS 332 0.0001

LYS 332 PRO 333 0.0003

PRO 333 GLU 334 -0.0001

GLU 334 TRP 335 0.0005

TRP 335 GLU 336 0.0001

GLU 336 ALA 337 0.0001

ALA 337 VAL 338 0.0001

VAL 338 VAL 339 0.0000

VAL 339 ALA 340 0.0002

ALA 340 LYS 341 0.0000

LYS 341 TYR 342 -0.0001

TYR 342 ARG 343 0.0019

ARG 343 PRO 344 -0.0002

PRO 344 ARG 345 -0.0001

ARG 345 LEU 346 -0.0003

LEU 346 GLU 347 0.0001

GLU 347 GLY 348 0.0001

GLY 348 LYS 349 0.0001

LYS 349 ARG 350 0.0001

ARG 350 VAL 351 -0.0001

VAL 351 MET 352 0.0003

MET 352 LEU 353 0.0001

LEU 353 TYR 354 0.0001

TYR 354 ILE 355 0.0002

ILE 355 GLY 356 -0.0002

GLY 356 GLY 357 0.0005

GLY 357 LEU 358 0.0001

LEU 358 ARG 359 -0.0003

ARG 359 PRO 360 -0.0001

PRO 360 ARG 361 0.0003

ARG 361 HIS 362 -0.0000

HIS 362 VAL 363 -0.0001

VAL 363 ILE 364 -0.0002

ILE 364 GLY 365 -0.0000

GLY 365 ALA 366 0.0000

ALA 366 TYR 367 0.0003

TYR 367 GLU 368 -0.0002

GLU 368 ASP 369 -0.0012

ASP 369 LEU 370 0.0002

LEU 370 GLY 371 -0.0000

GLY 371 MET 372 -0.0001

MET 372 GLU 373 -0.0001

GLU 373 VAL 374 0.0001

VAL 374 VAL 375 0.0002

VAL 375 GLY 376 0.0001

GLY 376 THR 377 0.0003

THR 377 GLY 378 -0.0002

GLY 378 TYR 379 -0.0002

TYR 379 GLU 380 0.0001

GLU 380 PHE 381 -0.0005

PHE 381 ALA 382 0.0048

ALA 382 HIS 383 0.0001

HIS 383 ASN 384 0.0001

ASN 384 ASP 385 -0.0002

ASP 385 ASP 386 -0.0001

ASP 386 TYR 387 -0.0001

TYR 387 ASP 388 -0.0001

ASP 388 ARG 389 -0.0003

ARG 389 THR 390 -0.0001

THR 390 MET 391 0.0002

MET 391 LYS 392 0.0000

LYS 392 GLU 393 0.0005

GLU 393 MET 394 -0.0003

MET 394 GLY 395 0.0048

GLY 395 ASP 396 0.0001

ASP 396 SER 397 0.0001

SER 397 THR 398 -0.0004

THR 398 LEU 399 0.0003

LEU 399 LEU 400 -0.0001

LEU 400 TYR 401 0.0001

TYR 401 ASP 402 0.0001

ASP 402 ASP 403 -0.0002

ASP 403 VAL 404 -0.0003

VAL 404 THR 405 0.0003

THR 405 GLY 406 0.0002

GLY 406 TYR 407 -0.0000

TYR 407 GLU 408 0.0022

GLU 408 PHE 409 -0.0001

PHE 409 GLU 410 0.0001

GLU 410 GLU 411 0.0002

GLU 411 PHE 412 0.0003

PHE 412 VAL 413 0.0003

VAL 413 LYS 414 -0.0004

LYS 414 ARG 415 -0.0003

ARG 415 ILE 416 0.0004

ILE 416 LYS 417 -0.0003

LYS 417 PRO 418 0.0002

PRO 418 ASP 419 -0.0002

ASP 419 LEU 420 -0.0001

LEU 420 ILE 421 0.0204

ILE 421 GLY 422 0.0000

GLY 422 SER 423 -0.0004

SER 423 GLY 424 0.0002

GLY 424 ILE 425 0.0001

ILE 425 LYS 426 0.0003

LYS 426 GLU 427 -0.0000

GLU 427 LYS 428 0.0001

LYS 428 PHE 429 0.0003

PHE 429 ILE 430 -0.0002

ILE 430 PHE 431 0.0000

PHE 431 GLN 432 -0.0003

GLN 432 LYS 433 -0.0001

LYS 433 MET 434 0.0043

MET 434 GLY 435 0.0002

GLY 435 ILE 436 -0.0003

ILE 436 PRO 437 -0.0002

PRO 437 PHE 438 0.0001

PHE 438 ARG 439 0.0000

ARG 439 GLU 440 -0.0004

GLU 440 MET 441 0.0000

MET 441 HIS 442 -0.0003

HIS 442 SER 443 -0.0001

SER 443 TRP 444 -0.0001

TRP 444 ASP 445 0.0002

ASP 445 TYR 446 -0.0001

TYR 446 SER 447 -0.0061

SER 447 GLY 448 -0.0004

GLY 448 PRO 449 0.0003

PRO 449 TYR 450 0.0003

TYR 450 HIS 451 -0.0002

HIS 451 GLY 452 -0.0003

GLY 452 PHE 453 0.0003

PHE 453 ASP 454 -0.0000

ASP 454 GLY 455 0.0001

GLY 455 PHE 456 0.0001

PHE 456 ALA 457 -0.0002

ALA 457 ILE 458 0.0000

ILE 458 PHE 459 0.0004

PHE 459 ALA 460 0.0009

ALA 460 ARG 461 -0.0003

ARG 461 ASP 462 -0.0005

ASP 462 MET 463 -0.0001

MET 463 ASP 464 -0.0000

ASP 464 MET 465 0.0002

MET 465 THR 466 -0.0005

THR 466 LEU 467 0.0002

LEU 467 ASN 468 -0.0003

ASN 468 ASN 469 0.0002

ASN 469 PRO 470 -0.0004

PRO 470 CYS 471 -0.0003

CYS 471 TRP 472 -0.0001

TRP 472 LYS 473 0.0035

LYS 473 LYS 474 0.0002

LYS 474 LEU 475 0.0001

LEU 475 GLN 476 -0.0000

GLN 476 ALA 477 0.0000

ALA 477 PRO 478 0.0001

PRO 478 TRP 479 -0.0002

TRP 479 GLU 480 0.0005

GLU 480 SER 2 0.0021

SER 2 GLN 3 0.0004

GLN 3 GLN 4 0.0001

GLN 4 VAL 5 0.0002

VAL 5 ASP 6 0.0000

ASP 6 LYS 7 0.0000

LYS 7 ILE 8 0.0001

ILE 8 LYS 9 -0.0001

LYS 9 ALA 10 -0.0002

ALA 10 SER 11 -0.0001

SER 11 TYR 12 0.0003

TYR 12 PRO 13 -0.0002

PRO 13 LEU 14 -0.0001

LEU 14 PHE 15 0.0039

PHE 15 LEU 16 0.0002

LEU 16 ASP 17 -0.0005

ASP 17 GLN 18 0.0004

GLN 18 ASP 19 -0.0001

ASP 19 TYR 20 -0.0002

TYR 20 LYS 21 -0.0000

LYS 21 ASP 22 0.0001

ASP 22 MET 23 0.0000

MET 23 LEU 24 -0.0003

LEU 24 ALA 25 -0.0001

ALA 25 LYS 26 -0.0002

LYS 26 LYS 27 -0.0001

LYS 27 ARG 28 -0.0038

ARG 28 ASP 29 0.0003

ASP 29 GLY 30 -0.0003

GLY 30 PHE 31 0.0001

PHE 31 GLU 32 0.0004

GLU 32 GLU 33 -0.0000

GLU 33 LYS 34 -0.0001

LYS 34 TYR 35 0.0003

TYR 35 PRO 36 -0.0001

PRO 36 GLN 37 -0.0000

GLN 37 ASP 38 0.0005

ASP 38 LYS 39 -0.0003

LYS 39 ILE 40 -0.0001

ILE 40 ASP 41 -0.0043

ASP 41 GLU 42 -0.0003

GLU 42 VAL 43 0.0002

VAL 43 PHE 44 0.0001

PHE 44 GLN 45 -0.0003

GLN 45 GLN 45 0.0000

GLN 45 TRP 46 0.0001

TRP 46 THR 47 0.0001

THR 47 THR 48 0.0004

THR 48 THR 49 -0.0001

THR 49 LYS 50 0.0001

LYS 50 GLU 51 0.0001

GLU 51 TYR 52 -0.0002

TYR 52 GLN 53 -0.0001

GLN 53 GLU 54 0.0131

GLU 54 LEU 55 0.0005

LEU 55 ASN 56 -0.0000

ASN 56 PHE 57 0.0000

PHE 57 GLN 58 0.0001

GLN 58 ARG 59 0.0002

ARG 59 GLU 60 -0.0002

GLU 60 ALA 61 -0.0003

ALA 61 LEU 62 0.0002

LEU 62 THR 63 0.0000

THR 63 VAL 64 -0.0002

VAL 64 ASN 65 -0.0000

ASN 65 PRO 66 0.0001

PRO 66 ALA 67 -0.0193

ALA 67 LYS 68 0.0001

LYS 68 ALA 69 0.0001

ALA 69 CYS 70 -0.0001

CYS 70 GLN 71 -0.0002

GLN 71 PRO 72 0.0000

PRO 72 LEU 73 0.0001

LEU 73 GLY 74 -0.0001

GLY 74 ALA 75 -0.0004

ALA 75 VAL 76 0.0004

VAL 76 LEU 77 -0.0001

LEU 77 CYS 78 0.0002

CYS 78 ALA 79 0.0003

ALA 79 LEU 80 -0.0010

LEU 80 GLY 81 -0.0000

GLY 81 PHE 82 -0.0003

PHE 82 GLU 83 -0.0002

GLU 83 LYS 84 0.0002

LYS 84 THR 85 -0.0002

THR 85 MET 86 0.0002

MET 86 PRO 87 -0.0001

PRO 87 TYR 88 0.0002

TYR 88 VAL 89 0.0005

VAL 89 HIS 90 -0.0001

HIS 90 GLY 91 -0.0003

GLY 91 SER 92 0.0000

SER 92 GLN 93 -0.0193

GLN 93 GLY 94 -0.0002

GLY 94 CYS 95 0.0003

CYS 95 VAL 96 -0.0003

VAL 96 ALA 97 -0.0004

ALA 97 TYR 98 0.0001

TYR 98 PHE 99 -0.0003

PHE 99 ARG 100 -0.0002

ARG 100 SER 101 0.0002

SER 101 TYR 102 0.0000

TYR 102 PHE 103 -0.0001

PHE 103 ASN 104 0.0006

ASN 104 ARG 105 -0.0001

ARG 105 HIS 106 -0.0172

HIS 106 PHE 107 0.0004

PHE 107 ARG 108 -0.0001

ARG 108 GLU 109 0.0005

GLU 109 PRO 110 -0.0002

PRO 110 VAL 111 -0.0005

VAL 111 SER 112 -0.0001

SER 112 CYS 113 0.0005

CYS 113 VAL 114 -0.0002

VAL 114 SER 115 -0.0003

SER 115 ASP 116 0.0001

ASP 116 SER 117 0.0000

SER 117 MET 118 -0.0001

MET 118 THR 119 -0.0213

THR 119 GLU 120 -0.0002

GLU 120 ASP 121 0.0001

ASP 121 ALA 122 0.0001

ALA 122 ALA 123 -0.0002

ALA 123 VAL 124 -0.0000

VAL 124 PHE 125 -0.0001

PHE 125 GLY 126 0.0003

GLY 126 GLY 127 0.0000

GLY 127 GLN 128 0.0002

GLN 128 GLN 129 -0.0001

GLN 129 ASN 130 0.0003

ASN 130 MET 131 -0.0003

MET 131 LYS 132 0.0052

LYS 132 ASP 133 0.0004

ASP 133 GLY 134 -0.0001

GLY 134 LEU 135 -0.0001

LEU 135 GLN 136 -0.0001

GLN 136 ASN 137 0.0003

ASN 137 CYS 138 0.0001

CYS 138 LYS 139 0.0003

LYS 139 ALA 140 -0.0001

ALA 140 THR 141 0.0002

THR 141 TYR 142 -0.0001

TYR 142 LYS 143 -0.0001

LYS 143 PRO 144 0.0006

PRO 144 ASP 145 0.0223

ASP 145 MET 146 -0.0000

MET 146 ILE 147 -0.0004

ILE 147 ALA 148 -0.0002

ALA 148 VAL 149 -0.0004

VAL 149 SER 150 0.0002

SER 150 THR 151 -0.0002

THR 151 THR 152 0.0002

THR 152 CYS 153 -0.0002

CYS 153 MET 154 0.0001

MET 154 ALA 155 -0.0001

ALA 155 GLU 156 -0.0003

GLU 156 VAL 157 -0.0003

VAL 157 ILE 158 0.0293

ILE 158 GLY 159 -0.0002

GLY 159 ASP 160 -0.0003

ASP 160 ASP 161 -0.0002

ASP 161 LEU 162 -0.0002

LEU 162 ASN 163 -0.0003

ASN 163 ALA 164 -0.0004

ALA 164 PHE 165 0.0003

PHE 165 ILE 166 0.0001

ILE 166 ASN 167 0.0000

ASN 167 ASN 168 0.0001

ASN 168 SER 169 0.0003

SER 169 LYS 170 -0.0001

LYS 170 LYS 171 0.0131

LYS 171 GLU 172 0.0001

GLU 172 GLY 173 0.0005

GLY 173 PHE 174 -0.0001

PHE 174 ILE 175 0.0001

ILE 175 PRO 176 -0.0003

PRO 176 ASP 177 -0.0000

ASP 177 GLU 178 -0.0002

GLU 178 PHE 179 0.0005

PHE 179 PRO 180 -0.0002

PRO 180 VAL 181 -0.0004

VAL 181 PRO 182 0.0001

PRO 182 PHE 183 -0.0000

PHE 183 ALA 184 0.0059

ALA 184 HIS 185 0.0002

HIS 185 THR 186 -0.0000

THR 186 PRO 187 -0.0001

PRO 187 SER 188 0.0004

SER 188 PHE 189 -0.0004

PHE 189 VAL 190 0.0002

VAL 190 GLY 191 -0.0003

GLY 191 SER 192 0.0000

SER 192 HIS 193 -0.0002

HIS 193 VAL 194 0.0004

VAL 194 THR 195 0.0004

THR 195 GLY 196 0.0000

GLY 196 TRP 197 0.0050

TRP 197 ASP 198 -0.0001

ASP 198 ASN 199 0.0000

ASN 199 MET 200 -0.0004

MET 200 PHE 201 -0.0003

PHE 201 GLU 202 0.0003

GLU 202 GLY 203 -0.0002

GLY 203 ILE 204 -0.0002

ILE 204 ALA 205 -0.0002

ALA 205 ARG 206 -0.0003

ARG 206 TYR 207 -0.0000

TYR 207 PHE 208 0.0000

PHE 208 THR 209 0.0004

THR 209 LEU 210 0.0025

LEU 210 LYS 211 -0.0002

LYS 211 SER 212 0.0003

SER 212 MET 213 -0.0000

MET 213 ASP 214 -0.0003

ASP 214 ASP 215 0.0001

ASP 215 LYS 216 0.0000

LYS 216 VAL 217 0.0003

VAL 217 VAL 218 0.0001

VAL 218 GLY 219 -0.0003

GLY 219 SER 220 0.0003

SER 220 ASN 221 0.0000

ASN 221 LYS 222 -0.0002

LYS 222 LYS 223 -0.0050

LYS 223 ILE 224 -0.0000

ILE 224 ASN 225 0.0000

ASN 225 ILE 226 -0.0000

ILE 226 VAL 227 -0.0003

VAL 227 PRO 228 -0.0001

PRO 228 GLY 229 -0.0003

GLY 229 PHE 230 0.0000

PHE 230 GLU 231 -0.0002

GLU 231 THR 232 0.0000

THR 232 TYR 233 -0.0003

TYR 233 LEU 234 0.0002

LEU 234 GLY 235 0.0003

GLY 235 ASN 236 -0.0098

ASN 236 PHE 237 0.0001

PHE 237 ARG 238 -0.0005

ARG 238 VAL 239 -0.0004

VAL 239 ILE 240 0.0000

ILE 240 LYS 241 -0.0002

LYS 241 ARG 242 0.0002

ARG 242 MET 243 -0.0000

MET 243 LEU 244 -0.0005

LEU 244 SER 245 0.0002

SER 245 GLU 246 -0.0000

GLU 246 MET 247 0.0002

MET 247 GLY 248 0.0000

GLY 248 VAL 249 0.0061

VAL 249 GLY 250 0.0001

GLY 250 TYR 251 -0.0003

TYR 251 SER 252 0.0000

SER 252 LEU 253 -0.0000

LEU 253 LEU 254 0.0002

LEU 254 SER 255 -0.0002

SER 255 ASP 256 -0.0000

ASP 256 PRO 257 -0.0003

PRO 257 GLU 258 0.0001

GLU 258 GLU 259 0.0002

GLU 259 VAL 260 0.0001

VAL 260 LEU 261 -0.0000

LEU 261 ASP 262 0.0016

ASP 262 THR 263 0.0003

THR 263 PRO 264 -0.0001

PRO 264 ALA 265 0.0001

ALA 265 ASP 266 0.0003

ASP 266 GLY 267 0.0003

GLY 267 GLN 268 -0.0001

GLN 268 PHE 269 -0.0000

PHE 269 ARG 270 0.0003

ARG 270 MET 271 0.0000

MET 271 TYR 272 -0.0001

TYR 272 ALA 273 -0.0000

ALA 273 GLY 274 -0.0000

GLY 274 GLY 275 0.0096

GLY 275 THR 276 -0.0002

THR 276 THR 277 0.0001

THR 277 GLN 278 -0.0000

GLN 278 GLU 279 0.0003

GLU 279 GLU 280 0.0003

GLU 280 MET 281 -0.0000

MET 281 LYS 282 -0.0000

LYS 282 ASP 283 0.0002

ASP 283 ALA 284 0.0000

ALA 284 PRO 285 0.0006

PRO 285 ASN 286 0.0001

ASN 286 ALA 287 0.0001

ALA 287 LEU 288 0.0045

LEU 288 ASN 289 0.0002

ASN 289 THR 290 -0.0000

THR 290 VAL 291 -0.0003

VAL 291 LEU 292 0.0005

LEU 292 LEU 293 0.0003

LEU 293 GLN 294 0.0001

GLN 294 PRO 295 -0.0003

PRO 295 TRP 296 0.0004

TRP 296 HIS 297 0.0000

HIS 297 LEU 298 -0.0001

LEU 298 GLU 299 -0.0005

GLU 299 LYS 300 0.0002

LYS 300 THR 301 -0.0100

THR 301 LYS 302 0.0002

LYS 302 LYS 303 0.0000

LYS 303 PHE 304 -0.0001

PHE 304 VAL 305 0.0003

VAL 305 GLU 306 0.0004

GLU 306 GLY 307 -0.0000

GLY 307 THR 308 -0.0001

THR 308 TRP 309 0.0004

TRP 309 LYS 310 -0.0002

LYS 310 HIS 311 0.0002

HIS 311 GLU 312 -0.0001

GLU 312 VAL 313 0.0001

VAL 313 PRO 314 0.0458

PRO 314 LYS 315 -0.0000

LYS 315 LEU 316 -0.0002

LEU 316 ASN 317 -0.0002

ASN 317 ILE 318 0.0004

ILE 318 PRO 319 0.0001

PRO 319 MET 320 -0.0004

MET 320 GLY 321 -0.0003

GLY 321 LEU 322 0.0002

LEU 322 ASP 323 -0.0001

ASP 323 TRP 324 0.0001

TRP 324 THR 325 -0.0001

THR 325 ASP 326 0.0000

ASP 326 GLU 327 0.0026

GLU 327 PHE 328 -0.0005

PHE 328 LEU 329 -0.0003

LEU 329 MET 330 -0.0000

MET 330 LYS 331 -0.0001

LYS 331 VAL 332 0.0001

VAL 332 SER 333 -0.0003

SER 333 GLU 334 0.0000

GLU 334 ILE 335 0.0002

ILE 335 SER 336 -0.0000

SER 336 GLY 337 -0.0001

GLY 337 GLN 338 0.0001

GLN 338 PRO 339 -0.0002

PRO 339 ILE 340 0.0102

ILE 340 PRO 341 0.0000

PRO 341 ALA 342 -0.0003

ALA 342 SER 343 0.0001

SER 343 LEU 344 -0.0002

LEU 344 THR 345 -0.0001

THR 345 LYS 346 -0.0001

LYS 346 GLU 347 -0.0004

GLU 347 ARG 348 -0.0004

ARG 348 GLY 349 -0.0000

GLY 349 ARG 350 -0.0003

ARG 350 LEU 351 -0.0004

LEU 351 VAL 352 -0.0002

VAL 352 ASP 353 0.0217

ASP 353 MET 354 0.0003

MET 354 MET 355 -0.0002

MET 355 THR 356 -0.0000

THR 356 ASP 357 -0.0003

ASP 357 SER 358 -0.0000

SER 358 HIS 359 0.0000

HIS 359 THR 360 -0.0002

THR 360 TRP 361 -0.0002

TRP 361 LEU 362 -0.0002

LEU 362 HIS 363 0.0002

HIS 363 GLY 364 0.0001

GLY 364 LYS 365 0.0002

LYS 365 ARG 366 0.0658

ARG 366 PHE 367 0.0001

PHE 367 ALA 368 -0.0001

ALA 368 LEU 369 -0.0001

LEU 369 TRP 370 -0.0000

TRP 370 GLY 371 0.0000

GLY 371 ASP 372 -0.0003

ASP 372 PRO 373 0.0001

PRO 373 ASP 374 -0.0001

ASP 374 PHE 375 0.0001

PHE 375 VAL 376 -0.0001

VAL 376 MET 377 0.0001

MET 377 GLY 378 -0.0002

GLY 378 LEU 379 0.0157

LEU 379 VAL 380 0.0000

VAL 380 LYS 381 -0.0002

LYS 381 PHE 382 0.0004

PHE 382 LEU 383 0.0000

LEU 383 LEU 384 0.0001

LEU 384 GLU 385 0.0002

GLU 385 LEU 386 -0.0000

LEU 386 GLY 387 0.0005

GLY 387 CYS 388 0.0002

CYS 388 GLU 389 -0.0002

GLU 389 PRO 390 -0.0001

PRO 390 VAL 391 0.0004

VAL 391 HIS 392 0.0313

HIS 392 ILE 393 -0.0001

ILE 393 LEU 394 -0.0003

LEU 394 CYS 395 0.0004

CYS 395 HIS 396 -0.0004

HIS 396 ASN 397 -0.0000

ASN 397 GLY 398 0.0000

GLY 398 ASN 399 0.0002

ASN 399 LYS 400 0.0002

LYS 400 ARG 401 0.0000

ARG 401 TRP 402 -0.0003

TRP 402 LYS 403 0.0001

LYS 403 LYS 404 0.0001

LYS 404 ALA 405 0.0250

ALA 405 VAL 406 0.0001

VAL 406 ASP 407 0.0001

ASP 407 ALA 408 -0.0000

ALA 408 ILE 409 0.0001

ILE 409 LEU 410 0.0001

LEU 410 ALA 411 -0.0003

ALA 411 ALA 412 -0.0000

ALA 412 SER 413 0.0003

SER 413 PRO 414 -0.0002

PRO 414 TYR 415 -0.0001

TYR 415 GLY 416 -0.0002

GLY 416 LYS 417 0.0002

LYS 417 ASN 418 -0.0051

ASN 418 ALA 419 0.0001

ALA 419 THR 420 -0.0002

THR 420 VAL 421 0.0001

VAL 421 TYR 422 -0.0003

TYR 422 ILE 423 0.0002

ILE 423 GLY 424 -0.0003

GLY 424 LYS 425 0.0002

LYS 425 ASP 426 -0.0001

ASP 426 LEU 427 -0.0003

LEU 427 TRP 428 0.0002

TRP 428 HIS 429 0.0000

HIS 429 LEU 430 0.0002

LEU 430 ARG 431 -0.0138

ARG 431 SER 432 -0.0000

SER 432 LEU 433 -0.0000

LEU 433 VAL 434 -0.0001

VAL 434 PHE 435 -0.0002

PHE 435 THR 436 0.0002

THR 436 ASP 437 0.0003

ASP 437 LYS 438 0.0000

LYS 438 PRO 439 -0.0003

PRO 439 ASP 440 -0.0000

ASP 440 PHE 441 -0.0002

PHE 441 MET 442 0.0003

MET 442 ILE 443 -0.0002

ILE 443 GLY 444 0.0109

GLY 444 ASN 445 0.0000

ASN 445 SER 446 0.0003

SER 446 TYR 447 0.0004

TYR 447 GLY 448 -0.0001

GLY 448 LYS 449 0.0001

LYS 449 PHE 450 0.0001

PHE 450 ILE 451 0.0003

ILE 451 GLN 452 0.0001

GLN 452 ARG 453 -0.0001

ARG 453 ASP 454 0.0001

ASP 454 THR 455 -0.0005

THR 455 LEU 456 -0.0002

LEU 456 HIS 457 0.0041

HIS 457 LYS 458 -0.0001

LYS 458 GLY 459 -0.0000

GLY 459 LYS 460 -0.0002

LYS 460 GLU 461 0.0001

GLU 461 PHE 462 -0.0002

PHE 462 GLU 463 0.0001

GLU 463 VAL 464 0.0000

VAL 464 PRO 465 0.0002

PRO 465 LEU 466 0.0002

LEU 466 ILE 467 -0.0003

ILE 467 ARG 468 0.0002

ARG 468 ILE 469 -0.0000

ILE 469 GLY 470 0.0228

GLY 470 PHE 471 0.0002

PHE 471 PRO 472 -0.0002

PRO 472 ILE 473 0.0001

ILE 473 PHE 474 -0.0003

PHE 474 ASP 475 0.0000

ASP 475 ARG 476 -0.0003

ARG 476 HIS 477 0.0003

HIS 477 HIS 478 -0.0005

HIS 478 LEU 479 -0.0002

LEU 479 HIS 480 0.0002

HIS 480 ARG 481 -0.0000

ARG 481 SER 482 -0.0001

SER 482 THR 483 -0.0206

THR 483 THR 484 0.0001

THR 484 LEU 485 -0.0001

LEU 485 GLY 486 0.0002

GLY 486 TYR 487 -0.0001

TYR 487 GLU 488 0.0001

GLU 488 GLY 489 0.0003

GLY 489 ALA 490 -0.0003

ALA 490 MET 491 0.0003

MET 491 GLN 492 0.0001

GLN 492 ILE 493 -0.0004

ILE 493 LEU 494 0.0004

LEU 494 THR 495 0.0001

THR 495 THR 496 0.0096

THR 496 LEU 497 0.0001

LEU 497 VAL 498 -0.0001

VAL 498 ASN 499 0.0002

ASN 499 SER 500 -0.0003

SER 500 ILE 501 -0.0001

ILE 501 LEU 502 0.0000

LEU 502 GLU 503 0.0002

GLU 503 ARG 504 -0.0003

ARG 504 LEU 505 -0.0000

LEU 505 ASP 506 0.0000

ASP 506 GLU 507 0.0000

GLU 507 GLU 508 -0.0000

GLU 508 THR 509 0.0537

THR 509 ARG 510 -0.0002

ARG 510 GLY 511 -0.0001

GLY 511 MET 512 -0.0000

MET 512 GLN 513 -0.0000

GLN 513 ALA 514 0.0005

ALA 514 THR 515 -0.0004

THR 515 ASP 516 0.0003

ASP 516 TYR 517 0.0003

TYR 517 ASN 518 0.0001

ASN 518 HIS 519 0.0001

HIS 519 ASP 520 -0.0004

ASP 520 LEU 521 0.0002

LEU 521 VAL 522 -0.0025

VAL 522 ARG 523 -0.0001

ARG 523 SER 5 -0.0004

SER 5 ARG 6 -0.0001

ARG 6 GLU 7 0.0000

GLU 7 GLU 8 -0.0000

GLU 8 VAL 9 -0.0002

VAL 9 GLU 10 -0.0002

GLU 10 SER 11 0.0000

SER 11 LEU 12 -0.0003

LEU 12 ILE 13 0.0001

ILE 13 GLN 14 0.0003

GLN 14 GLU 15 -0.0002

GLU 15 VAL 16 -0.0002

VAL 16 LEU 17 -0.0003

LEU 17 GLU 18 0.0016

GLU 18 VAL 19 -0.0001

VAL 19 TYR 20 -0.0005

TYR 20 PRO 21 -0.0003

PRO 21 GLU 22 -0.0002

GLU 22 LYS 23 0.0002

LYS 23 ALA 24 -0.0001

ALA 24 ARG 25 -0.0000

ARG 25 LYS 26 -0.0002

LYS 26 ASP 27 0.0002

ASP 27 ARG 28 -0.0000

ARG 28 ASN 29 0.0001

ASN 29 LYS 30 0.0000

LYS 30 HIS 31 -0.0014

HIS 31 LEU 32 0.0003

LEU 32 ALA 33 -0.0004

ALA 33 VAL 34 -0.0002

VAL 34 ASN 35 0.0001

ASN 35 ASP 36 -0.0001

ASP 36 PRO 37 -0.0001

PRO 37 ALA 38 -0.0001

ALA 38 VAL 39 0.0001

VAL 39 THR 40 0.0001

THR 40 GLN 41 -0.0002

GLN 41 SER 42 -0.0003

SER 42 LYS 43 -0.0001

LYS 43 LYS 44 0.0030

LYS 44 CYS 45 0.0000

CYS 45 ILE 46 0.0005

ILE 46 ILE 47 -0.0001

ILE 47 SER 48 0.0000

SER 48 ASN 49 0.0003

ASN 49 LYS 50 0.0004

LYS 50 LYS 51 -0.0001

LYS 51 SER 52 0.0001

SER 52 GLN 53 -0.0002

GLN 53 PRO 54 -0.0002

PRO 54 GLY 55 -0.0000

GLY 55 LEU 56 -0.0002

LEU 56 MET 57 0.0053

MET 57 THR 58 0.0000

THR 58 ILE 59 -0.0002

ILE 59 ARG 60 0.0003

ARG 60 GLY 61 0.0000

GLY 61 CYS 62 -0.0003

CYS 62 ALA 63 0.0004

ALA 63 TYR 64 0.0000

TYR 64 ALA 65 -0.0000

ALA 65 GLY 66 0.0000

GLY 66 SER 67 0.0000

SER 67 LYS 68 0.0001

LYS 68 GLY 69 -0.0000

GLY 69 VAL 70 -0.0013

VAL 70 VAL 71 -0.0001

VAL 71 TRP 72 -0.0002

TRP 72 GLY 73 0.0001

GLY 73 PRO 74 0.0002

PRO 74 ILE 75 0.0001

ILE 75 LYS 76 0.0001

LYS 76 ASP 77 -0.0002

ASP 77 MET 78 -0.0001

MET 78 ILE 79 -0.0005

ILE 79 HIS 80 -0.0001

HIS 80 ILE 81 0.0000

ILE 81 SER 82 -0.0003

SER 82 HIS 83 -0.0095

HIS 83 GLY 84 0.0001

GLY 84 PRO 85 -0.0001

PRO 85 VAL 86 0.0002

VAL 86 GLY 87 -0.0002

GLY 87 CYS 88 -0.0004

CYS 88 GLY 89 -0.0001

GLY 89 GLN 90 0.0001

GLN 90 TYR 91 -0.0002

TYR 91 SER 92 0.0001

SER 92 ARG 93 -0.0003

ARG 93 ALA 94 0.0003

ALA 94 GLY 95 0.0000

GLY 95 ARG 96 -0.0102

ARG 96 ARG 97 0.0001

ARG 97 ASN 98 0.0005

ASN 98 TYR 99 0.0001

TYR 99 TYR 100 -0.0003

TYR 100 ILE 101 0.0003

ILE 101 GLY 102 0.0001

GLY 102 THR 103 -0.0002

THR 103 THR 104 -0.0003

THR 104 GLY 105 -0.0003

GLY 105 VAL 106 -0.0004

VAL 106 ASN 107 -0.0001

ASN 107 ALA 108 0.0002

ALA 108 PHE 109 0.0027

PHE 109 VAL 110 0.0000

VAL 110 THR 111 -0.0004

THR 111 MET 112 -0.0002

MET 112 ASN 113 0.0001

ASN 113 PHE 114 0.0002

PHE 114 THR 115 0.0001

THR 115 SER 116 -0.0002

SER 116 ASP 117 -0.0002

ASP 117 PHE 118 0.0001

PHE 118 GLN 119 -0.0000

GLN 119 GLU 120 -0.0003

GLU 120 LYS 121 0.0002

LYS 121 ASP 122 -0.0050

ASP 122 ILE 123 0.0001

ILE 123 VAL 124 -0.0002

VAL 124 PHE 125 -0.0002

PHE 125 GLY 126 0.0000

GLY 126 GLY 127 -0.0000

GLY 127 ASP 128 0.0002

ASP 128 LYS 129 0.0002

LYS 129 LYS 130 -0.0003

LYS 130 LEU 131 -0.0003

LEU 131 ALA 132 0.0001

ALA 132 LYS 133 -0.0000

LYS 133 LEU 134 -0.0003

LEU 134 ILE 135 0.0009

ILE 135 ASP 136 -0.0003

ASP 136 GLU 137 -0.0002

GLU 137 VAL 138 -0.0002

VAL 138 GLU 139 0.0001

GLU 139 THR 140 -0.0000

THR 140 LEU 141 -0.0001

LEU 141 PHE 142 -0.0001

PHE 142 PRO 143 0.0002

PRO 143 LEU 144 -0.0002

LEU 144 ASN 145 -0.0003

ASN 145 LYS 146 -0.0000

LYS 146 GLY 147 0.0004

GLY 147 ILE 148 0.0042

ILE 148 SER 149 -0.0000

SER 149 VAL 150 -0.0004

VAL 150 GLN 151 0.0002

GLN 151 SER 152 -0.0002

SER 152 GLU 153 0.0005

GLU 153 CYS 154 -0.0002

CYS 154 PRO 155 0.0003

PRO 155 ILE 156 -0.0003

ILE 156 GLY 157 0.0002

GLY 157 LEU 158 -0.0001

LEU 158 ILE 159 -0.0002

ILE 159 GLY 160 0.0001

GLY 160 ASP 161 -0.0012

ASP 161 ASP 162 -0.0001

ASP 162 ILE 163 0.0002

ILE 163 GLU 164 0.0003

GLU 164 SER 165 0.0002

SER 165 VAL 166 -0.0002

VAL 166 SER 167 0.0000

SER 167 LYS 168 -0.0001

LYS 168 VAL 169 -0.0000

VAL 169 LYS 170 0.0001

LYS 170 GLY 171 -0.0001

GLY 171 ALA 172 -0.0001

ALA 172 GLU 173 -0.0003

GLU 173 LEU 174 0.0013

LEU 174 SER 175 -0.0001

SER 175 LYS 176 -0.0001

LYS 176 THR 177 0.0000

THR 177 ILE 178 0.0002

ILE 178 VAL 179 -0.0001

VAL 179 PRO 180 -0.0004

PRO 180 VAL 181 0.0000

VAL 181 ARG 182 -0.0001

ARG 182 CYS 183 0.0000

CYS 183 GLU 184 0.0001

GLU 184 GLY 185 -0.0001

GLY 185 PHE 186 -0.0003

PHE 186 ARG 187 -0.0063

ARG 187 GLY 188 0.0000

GLY 188 VAL 189 0.0000

VAL 189 SER 190 0.0000

SER 190 GLN 191 0.0001

GLN 191 SER 192 0.0002

SER 192 LEU 193 0.0001

LEU 193 GLY 194 0.0000

GLY 194 HIS 195 0.0002

HIS 195 HIS 196 -0.0004

HIS 196 ILE 197 0.0000

ILE 197 ALA 198 0.0002

ALA 198 ASN 199 0.0001

ASN 199 ASP 200 0.0036

ASP 200 ALA 201 0.0000

ALA 201 VAL 202 0.0004

VAL 202 ARG 203 0.0001

ARG 203 ASP 204 0.0003

ASP 204 TRP 205 0.0001

TRP 205 VAL 206 0.0001

VAL 206 LEU 207 0.0002

LEU 207 GLY 208 0.0002

GLY 208 LYS 209 -0.0002

LYS 209 ARG 210 -0.0001

ARG 210 ASP 211 -0.0002

ASP 211 GLU 212 0.0001

GLU 212 ASP 213 -0.0012

ASP 213 THR 214 -0.0003

THR 214 THR 215 0.0001

THR 215 PHE 216 -0.0002

PHE 216 ALA 217 0.0001

ALA 217 SER 218 -0.0002

SER 218 THR 219 -0.0001

THR 219 PRO 220 0.0003

PRO 220 TYR 221 -0.0000

TYR 221 ASP 222 -0.0002

ASP 222 VAL 223 0.0003

VAL 223 ALA 224 0.0001

ALA 224 ILE 225 -0.0001

ILE 225 ILE 226 -0.0030

ILE 226 GLY 227 0.0001

GLY 227 ASP 228 0.0000

ASP 228 TYR 229 0.0000

TYR 229 ASN 230 0.0003

ASN 230 ILE 231 0.0000

ILE 231 GLY 232 0.0001

GLY 232 GLY 233 0.0001

GLY 233 ASP 234 -0.0001

ASP 234 ALA 235 0.0001

ALA 235 TRP 236 -0.0003

TRP 236 SER 237 0.0004

SER 237 SER 238 0.0001

SER 238 ARG 239 0.0037

ARG 239 ILE 240 -0.0004

ILE 240 LEU 241 -0.0000

LEU 241 LEU 242 -0.0001

LEU 242 GLU 243 -0.0002

GLU 243 GLU 244 0.0001

GLU 244 MET 245 -0.0001

MET 245 GLY 246 0.0004

GLY 246 LEU 247 -0.0001

LEU 247 ARG 248 -0.0001

ARG 248 CYS 249 0.0003

CYS 249 VAL 250 0.0003

VAL 250 ALA 251 0.0001

ALA 251 GLN 252 -0.0020

GLN 252 TRP 253 0.0004

TRP 253 SER 254 0.0002

SER 254 GLY 255 -0.0001

GLY 255 ASP 256 0.0002

ASP 256 GLY 257 -0.0004

GLY 257 SER 258 0.0001

SER 258 ILE 259 0.0003

ILE 259 SER 260 0.0001

SER 260 GLU 261 0.0001

GLU 261 ILE 262 0.0000

ILE 262 GLU 263 -0.0002

GLU 263 LEU 264 0.0001

LEU 264 THR 265 -0.0038

THR 265 PRO 266 0.0000

PRO 266 LYS 267 -0.0002

LYS 267 VAL 268 0.0000

VAL 268 LYS 269 -0.0002

LYS 269 LEU 270 -0.0002

LEU 270 ASN 271 0.0001

ASN 271 LEU 272 -0.0000

LEU 272 VAL 273 0.0001

VAL 273 HIS 274 -0.0004

HIS 274 CYS 275 0.0001

CYS 275 TYR 276 -0.0001

TYR 276 ARG 277 0.0002

ARG 277 SER 278 -0.0026

SER 278 MET 279 0.0003

MET 279 ASN 280 -0.0001

ASN 280 TYR 281 -0.0000

TYR 281 ILE 282 -0.0000

ILE 282 SER 283 -0.0003

SER 283 ARG 284 0.0001

ARG 284 HIS 285 0.0005

HIS 285 MET 286 0.0000

MET 286 GLU 287 -0.0003

GLU 287 GLU 288 -0.0000

GLU 288 LYS 289 -0.0000

LYS 289 TYR 290 -0.0002

TYR 290 GLY 291 -0.0005

GLY 291 ILE 292 0.0003

ILE 292 PRO 293 0.0003

PRO 293 TRP 294 -0.0002

TRP 294 MET 295 0.0002

MET 295 GLU 296 -0.0001

GLU 296 TYR 297 0.0005

TYR 297 ASN 298 -0.0003

ASN 298 PHE 299 0.0003

PHE 299 PHE 300 0.0003

PHE 300 GLY 301 0.0001

GLY 301 PRO 302 -0.0000

PRO 302 THR 303 0.0004

THR 303 LYS 304 0.0021

LYS 304 THR 305 -0.0001

THR 305 ILE 306 -0.0004

ILE 306 GLU 307 -0.0000

GLU 307 SER 308 -0.0001

SER 308 LEU 309 0.0000

LEU 309 ARG 310 -0.0001

ARG 310 ALA 311 -0.0002

ALA 311 ILE 312 0.0003

ILE 312 ALA 313 0.0001

ALA 313 ALA 314 0.0000

ALA 314 LYS 315 0.0002

LYS 315 PHE 316 -0.0000

PHE 316 ASP 317 -0.0010

ASP 317 GLU 318 -0.0004

GLU 318 SER 319 0.0001

SER 319 ILE 320 -0.0001

ILE 320 GLN 321 0.0001

GLN 321 LYS 322 -0.0002

LYS 322 LYS 323 -0.0003

LYS 323 CYS 324 0.0003

CYS 324 GLU 325 -0.0001

GLU 325 GLU 326 -0.0002

GLU 326 VAL 327 -0.0004

VAL 327 ILE 328 -0.0004

ILE 328 ALA 329 -0.0002

ALA 329 LYS 330 -0.0001

LYS 330 TYR 331 -0.0001

TYR 331 LYS 332 0.0001

LYS 332 PRO 333 -0.0002

PRO 333 GLU 334 -0.0000

GLU 334 TRP 335 -0.0003

TRP 335 GLU 336 -0.0001

GLU 336 ALA 337 0.0000

ALA 337 VAL 338 -0.0003

VAL 338 VAL 339 -0.0002

VAL 339 ALA 340 0.0001

ALA 340 LYS 341 -0.0004

LYS 341 TYR 342 0.0001

TYR 342 ARG 343 -0.0064

ARG 343 PRO 344 -0.0004

PRO 344 ARG 345 -0.0000

ARG 345 LEU 346 -0.0002

LEU 346 GLU 347 -0.0003

GLU 347 GLY 348 -0.0002

GLY 348 LYS 349 0.0000

LYS 349 ARG 350 0.0004

ARG 350 VAL 351 -0.0002

VAL 351 MET 352 0.0000

MET 352 LEU 353 -0.0000

LEU 353 TYR 354 0.0003

TYR 354 ILE 355 0.0000

ILE 355 GLY 356 0.0018

GLY 356 GLY 357 -0.0000

GLY 357 LEU 358 0.0002

LEU 358 ARG 359 0.0001

ARG 359 PRO 360 0.0002

PRO 360 ARG 361 0.0000

ARG 361 HIS 362 0.0003

HIS 362 VAL 363 -0.0000

VAL 363 ILE 364 -0.0003

ILE 364 GLY 365 -0.0002

GLY 365 ALA 366 -0.0001

ALA 366 TYR 367 -0.0005

TYR 367 GLU 368 -0.0001

GLU 368 ASP 369 0.0008

ASP 369 LEU 370 0.0001

LEU 370 GLY 371 0.0000

GLY 371 MET 372 0.0003

MET 372 GLU 373 0.0000

GLU 373 VAL 374 0.0002

VAL 374 VAL 375 -0.0000

VAL 375 GLY 376 -0.0001

GLY 376 THR 377 0.0002

THR 377 GLY 378 -0.0003

GLY 378 TYR 379 0.0000

TYR 379 GLU 380 0.0002

GLU 380 PHE 381 0.0002

PHE 381 ALA 382 -0.0019

ALA 382 HIS 383 0.0002

HIS 383 ASN 384 -0.0001

ASN 384 ASP 385 -0.0001

ASP 385 ASP 386 0.0001

ASP 386 TYR 387 0.0002

TYR 387 ASP 388 -0.0003

ASP 388 ARG 389 -0.0000

ARG 389 THR 390 -0.0000

THR 390 MET 391 -0.0000

MET 391 LYS 392 0.0000

LYS 392 GLU 393 0.0003

GLU 393 MET 394 -0.0001

MET 394 GLY 395 -0.0007

GLY 395 ASP 396 0.0002

ASP 396 SER 397 0.0000

SER 397 THR 398 -0.0002

THR 398 LEU 399 -0.0002

LEU 399 LEU 400 -0.0001

LEU 400 TYR 401 0.0002

TYR 401 ASP 402 -0.0001

ASP 402 ASP 403 0.0003

ASP 403 VAL 404 -0.0001

VAL 404 THR 405 -0.0001

THR 405 GLY 406 -0.0001

GLY 406 TYR 407 0.0000

TYR 407 GLU 408 -0.0031

GLU 408 PHE 409 0.0003

PHE 409 GLU 410 -0.0002

GLU 410 GLU 411 0.0000

GLU 411 PHE 412 0.0003

PHE 412 VAL 413 0.0000

VAL 413 LYS 414 0.0003

LYS 414 ARG 415 0.0002

ARG 415 ILE 416 0.0003

ILE 416 LYS 417 -0.0000

LYS 417 PRO 418 0.0002

PRO 418 ASP 419 -0.0000

ASP 419 LEU 420 0.0004

LEU 420 ILE 421 -0.0115

ILE 421 GLY 422 0.0001

GLY 422 SER 423 0.0002

SER 423 GLY 424 -0.0001

GLY 424 ILE 425 -0.0001

ILE 425 LYS 426 0.0000

LYS 426 GLU 427 0.0003

GLU 427 LYS 428 -0.0002

LYS 428 PHE 429 -0.0001

PHE 429 ILE 430 0.0001

ILE 430 PHE 431 -0.0002

PHE 431 GLN 432 0.0002

GLN 432 LYS 433 0.0000

LYS 433 MET 434 -0.0029

MET 434 GLY 435 0.0000

GLY 435 ILE 436 0.0000

ILE 436 PRO 437 0.0002

PRO 437 PHE 438 0.0001

PHE 438 ARG 439 -0.0005

ARG 439 GLU 440 0.0001

GLU 440 MET 441 -0.0004

MET 441 HIS 442 -0.0001

HIS 442 SER 443 0.0000

SER 443 TRP 444 0.0002

TRP 444 ASP 445 0.0002

ASP 445 TYR 446 0.0003

TYR 446 SER 447 -0.0019

SER 447 GLY 448 -0.0001

GLY 448 PRO 449 0.0001

PRO 449 TYR 450 -0.0000

TYR 450 HIS 451 0.0002

HIS 451 GLY 452 -0.0003

GLY 452 PHE 453 0.0001

PHE 453 ASP 454 -0.0001

ASP 454 GLY 455 -0.0001

GLY 455 PHE 456 -0.0000

PHE 456 ALA 457 0.0000

ALA 457 ILE 458 -0.0001

ILE 458 PHE 459 0.0001

PHE 459 ALA 460 0.0144

ALA 460 ARG 461 -0.0002

ARG 461 ASP 462 0.0000

ASP 462 MET 463 -0.0000

MET 463 ASP 464 0.0001

ASP 464 MET 465 -0.0003

MET 465 THR 466 0.0002

THR 466 LEU 467 -0.0001

LEU 467 ASN 468 -0.0000

ASN 468 ASN 469 -0.0003

ASN 469 PRO 470 0.0003

PRO 470 CYS 471 -0.0001

CYS 471 TRP 472 0.0002

TRP 472 LYS 473 0.0145

LYS 473 LYS 474 0.0002

LYS 474 LEU 475 0.0001

LEU 475 GLN 476 -0.0002

GLN 476 ALA 477 -0.0003

ALA 477 PRO 478 0.0002

PRO 478 TRP 479 0.0000

TRP 479 GLU 480 -0.0001

GLU 480 SER 2 0.0036

SER 2 GLN 3 0.0000

GLN 3 GLN 4 0.0003

GLN 4 VAL 5 0.0001

VAL 5 ASP 6 -0.0001

ASP 6 LYS 7 0.0000

LYS 7 ILE 8 0.0002

ILE 8 LYS 9 -0.0001

LYS 9 ALA 10 0.0001

ALA 10 SER 11 -0.0001

SER 11 TYR 12 0.0002

TYR 12 PRO 13 -0.0002

PRO 13 LEU 14 -0.0002

LEU 14 PHE 15 0.0080

PHE 15 LEU 16 0.0002

LEU 16 ASP 17 -0.0000

ASP 17 GLN 18 0.0002

GLN 18 ASP 19 0.0002

ASP 19 TYR 20 0.0005

TYR 20 LYS 21 -0.0000

LYS 21 ASP 22 0.0004

ASP 22 MET 23 0.0002

MET 23 LEU 24 0.0002

LEU 24 ALA 25 -0.0003

ALA 25 LYS 26 -0.0001

LYS 26 LYS 27 0.0004

LYS 27 ARG 28 -0.0043

ARG 28 ASP 29 -0.0000

ASP 29 GLY 30 -0.0002

GLY 30 PHE 31 0.0001

PHE 31 GLU 32 0.0001

GLU 32 GLU 33 -0.0000

GLU 33 LYS 34 0.0001

LYS 34 TYR 35 -0.0002

TYR 35 PRO 36 0.0003

PRO 36 GLN 37 -0.0003

GLN 37 ASP 38 -0.0001

ASP 38 LYS 39 0.0000

LYS 39 ILE 40 0.0004

ILE 40 ASP 41 -0.0020

ASP 41 GLU 42 -0.0001

GLU 42 VAL 43 -0.0003

VAL 43 PHE 44 0.0001

PHE 44 GLN 45 -0.0000

GLN 45 TRP 46 0.0003

TRP 46 THR 47 -0.0000

THR 47 THR 48 0.0000

THR 48 THR 49 -0.0004

THR 49 LYS 50 0.0002

LYS 50 GLU 51 0.0001

GLU 51 TYR 52 0.0004

TYR 52 GLN 53 -0.0003

GLN 53 GLU 54 -0.0012

GLU 54 LEU 55 -0.0003

LEU 55 ASN 56 -0.0001

ASN 56 PHE 57 -0.0001

PHE 57 GLN 58 0.0002

GLN 58 ARG 59 -0.0002

ARG 59 GLU 60 -0.0000

GLU 60 ALA 61 0.0003

ALA 61 LEU 62 -0.0002

LEU 62 THR 63 0.0003

THR 63 VAL 64 0.0001

VAL 64 ASN 65 -0.0002

ASN 65 PRO 66 -0.0001

PRO 66 ALA 67 -0.0015

ALA 67 LYS 68 0.0004

LYS 68 ALA 69 0.0001

ALA 69 CYS 70 -0.0001

CYS 70 GLN 71 -0.0000

GLN 71 PRO 72 0.0003

PRO 72 LEU 73 -0.0002

LEU 73 GLY 74 0.0001

GLY 74 ALA 75 0.0001

ALA 75 VAL 76 0.0001

VAL 76 LEU 77 -0.0001

LEU 77 CYS 78 0.0002

CYS 78 ALA 79 -0.0002

ALA 79 LEU 80 0.0012

LEU 80 GLY 81 -0.0001

GLY 81 PHE 82 0.0001

PHE 82 GLU 83 -0.0000

GLU 83 LYS 84 -0.0001

LYS 84 THR 85 0.0002

THR 85 MET 86 0.0003

MET 86 PRO 87 0.0002

PRO 87 TYR 88 0.0005

TYR 88 VAL 89 0.0000

VAL 89 HIS 90 0.0001

HIS 90 GLY 91 0.0001

GLY 91 SER 92 0.0003

SER 92 GLN 93 0.0040

GLN 93 GLY 94 0.0002

GLY 94 CYS 95 -0.0000

CYS 95 VAL 96 0.0003

VAL 96 ALA 97 -0.0000

ALA 97 TYR 98 -0.0001

TYR 98 PHE 99 -0.0001

PHE 99 ARG 100 0.0001

ARG 100 SER 101 -0.0001

SER 101 TYR 102 -0.0002

TYR 102 PHE 103 0.0003

PHE 103 ASN 104 0.0000

ASN 104 ARG 105 0.0001

ARG 105 HIS 106 0.0009

HIS 106 PHE 107 0.0001

PHE 107 ARG 108 0.0002

ARG 108 GLU 109 -0.0002

GLU 109 PRO 110 0.0003

PRO 110 VAL 111 -0.0001

VAL 111 SER 112 -0.0000

SER 112 CYS 113 0.0000

CYS 113 VAL 114 -0.0003

VAL 114 SER 115 0.0002

SER 115 ASP 116 0.0003

ASP 116 SER 117 0.0001

SER 117 MET 118 -0.0002

MET 118 THR 119 0.0018

THR 119 GLU 120 -0.0001

GLU 120 ASP 121 -0.0003

ASP 121 ALA 122 -0.0004

ALA 122 ALA 123 -0.0002

ALA 123 VAL 124 0.0001

VAL 124 PHE 125 -0.0002

PHE 125 GLY 126 0.0002

GLY 126 GLY 127 -0.0000

GLY 127 GLN 128 0.0003

GLN 128 GLN 129 -0.0002

GLN 129 ASN 130 0.0001

ASN 130 MET 131 -0.0001

MET 131 LYS 132 0.0008

LYS 132 ASP 133 -0.0002

ASP 133 GLY 134 -0.0001

GLY 134 LEU 135 0.0002

LEU 135 GLN 136 0.0001

GLN 136 ASN 137 0.0004

ASN 137 CYS 138 -0.0001

CYS 138 LYS 139 -0.0002

LYS 139 ALA 140 -0.0002

ALA 140 THR 141 0.0001

THR 141 TYR 142 0.0001

TYR 142 LYS 143 -0.0005

LYS 143 PRO 144 0.0001

PRO 144 ASP 145 -0.0070

ASP 145 MET 146 0.0003

MET 146 ILE 147 -0.0002

ILE 147 ALA 148 0.0001

ALA 148 VAL 149 -0.0003

VAL 149 SER 150 0.0001

SER 150 THR 151 -0.0002

THR 151 THR 152 -0.0001

THR 152 CYS 153 0.0000

CYS 153 MET 154 0.0000

MET 154 ALA 155 0.0001

ALA 155 GLU 156 0.0000

GLU 156 VAL 157 0.0004

VAL 157 ILE 158 -0.0023

ILE 158 GLY 159 -0.0001

GLY 159 ASP 160 0.0001

ASP 160 ASP 161 -0.0004

ASP 161 LEU 162 0.0001

LEU 162 ASN 163 0.0002

ASN 163 ALA 164 0.0002

ALA 164 PHE 165 0.0004

PHE 165 ILE 166 -0.0003

ILE 166 ASN 167 0.0003

ASN 167 ASN 168 0.0001

ASN 168 SER 169 -0.0003

SER 169 LYS 170 0.0000

LYS 170 LYS 171 -0.0003

LYS 171 GLU 172 0.0001

GLU 172 GLY 173 -0.0001

GLY 173 PHE 174 -0.0000

PHE 174 ILE 175 0.0002

ILE 175 PRO 176 0.0000

PRO 176 ASP 177 0.0001

ASP 177 GLU 178 -0.0001

GLU 178 PHE 179 0.0001

PHE 179 PRO 180 -0.0003

PRO 180 VAL 181 0.0001

VAL 181 PRO 182 0.0002

PRO 182 PHE 183 -0.0002

PHE 183 ALA 184 0.0002

ALA 184 HIS 185 0.0003

HIS 185 THR 186 -0.0003

THR 186 PRO 187 -0.0002

PRO 187 SER 188 -0.0001

SER 188 PHE 189 -0.0001

PHE 189 VAL 190 0.0000

VAL 190 GLY 191 -0.0002

GLY 191 SER 192 -0.0003

SER 192 HIS 193 0.0003

HIS 193 VAL 194 0.0001

VAL 194 THR 195 -0.0002

THR 195 GLY 196 -0.0004

GLY 196 TRP 197 -0.0038

TRP 197 ASP 198 0.0001

ASP 198 ASN 199 -0.0001

ASN 199 MET 200 0.0001

MET 200 PHE 201 -0.0002

PHE 201 GLU 202 0.0002

GLU 202 GLY 203 -0.0002

GLY 203 ILE 204 -0.0001

ILE 204 ALA 205 0.0001

ALA 205 ARG 206 -0.0002

ARG 206 TYR 207 -0.0000

TYR 207 PHE 208 0.0003

PHE 208 THR 209 0.0001

THR 209 LEU 210 0.0020

LEU 210 LYS 211 -0.0000

LYS 211 SER 212 -0.0001

SER 212 MET 213 0.0002

MET 213 ASP 214 0.0002

ASP 214 ASP 215 -0.0002

ASP 215 LYS 216 -0.0001

LYS 216 VAL 217 0.0001

VAL 217 VAL 218 0.0004

VAL 218 GLY 219 -0.0003

GLY 219 SER 220 -0.0001

SER 220 ASN 221 0.0000

ASN 221 LYS 222 0.0002

LYS 222 LYS 223 0.0030

LYS 223 ILE 224 0.0001

ILE 224 ASN 225 0.0000

ASN 225 ILE 226 -0.0001

ILE 226 VAL 227 0.0003

VAL 227 PRO 228 0.0002

PRO 228 GLY 229 -0.0000

GLY 229 PHE 230 0.0002

PHE 230 GLU 231 -0.0001

GLU 231 THR 232 -0.0003

THR 232 TYR 233 0.0003

TYR 233 LEU 234 0.0001

LEU 234 GLY 235 -0.0000

GLY 235 ASN 236 0.0070

ASN 236 PHE 237 0.0001

PHE 237 ARG 238 -0.0002

ARG 238 VAL 239 0.0005

VAL 239 ILE 240 0.0000

ILE 240 LYS 241 0.0000

LYS 241 ARG 242 0.0001

ARG 242 MET 243 0.0002

MET 243 LEU 244 -0.0003

LEU 244 SER 245 -0.0000

SER 245 GLU 246 -0.0000

GLU 246 MET 247 0.0004

MET 247 GLY 248 -0.0001

GLY 248 VAL 249 -0.0167

VAL 249 GLY 250 -0.0002

GLY 250 TYR 251 -0.0000

TYR 251 SER 252 -0.0004

SER 252 LEU 253 -0.0001

LEU 253 LEU 254 -0.0004

LEU 254 SER 255 0.0001

SER 255 ASP 256 -0.0003

ASP 256 PRO 257 0.0001

PRO 257 GLU 258 -0.0002

GLU 258 GLU 259 0.0000

GLU 259 VAL 260 0.0002

VAL 260 LEU 261 0.0003

LEU 261 ASP 262 0.0009

ASP 262 THR 263 0.0002

THR 263 PRO 264 -0.0002

PRO 264 ALA 265 -0.0001

ALA 265 ASP 266 0.0003

ASP 266 GLY 267 0.0001

GLY 267 GLN 268 -0.0001

GLN 268 PHE 269 0.0002

PHE 269 ARG 270 -0.0001

ARG 270 MET 271 -0.0005

MET 271 TYR 272 -0.0001

TYR 272 ALA 273 0.0001

ALA 273 GLY 274 -0.0001

GLY 274 GLY 275 0.0072

GLY 275 THR 276 0.0003

THR 276 THR 277 -0.0003

THR 277 GLN 278 -0.0002

GLN 278 GLU 279 0.0002

GLU 279 GLU 280 -0.0000

GLU 280 MET 281 0.0001

MET 281 LYS 282 -0.0000

LYS 282 ASP 283 -0.0001

ASP 283 ALA 284 0.0002

ALA 284 PRO 285 0.0001

PRO 285 ASN 286 -0.0002

ASN 286 ALA 287 0.0003

ALA 287 LEU 288 -0.0035

LEU 288 ASN 289 0.0001

ASN 289 THR 290 0.0001

THR 290 VAL 291 -0.0002

VAL 291 LEU 292 0.0006

LEU 292 LEU 293 -0.0002

LEU 293 GLN 294 -0.0001

GLN 294 PRO 295 0.0003

PRO 295 TRP 296 -0.0003

TRP 296 HIS 297 0.0000

HIS 297 LEU 298 -0.0000

LEU 298 GLU 299 -0.0002

GLU 299 LYS 300 0.0001

LYS 300 THR 301 0.0044

THR 301 LYS 302 -0.0001

LYS 302 LYS 303 -0.0003

LYS 303 PHE 304 -0.0001

PHE 304 VAL 305 0.0002

VAL 305 GLU 306 -0.0000

GLU 306 GLY 307 0.0004

GLY 307 THR 308 -0.0000

THR 308 TRP 309 -0.0002

TRP 309 LYS 310 -0.0001

LYS 310 HIS 311 -0.0002

HIS 311 GLU 312 -0.0001

GLU 312 VAL 313 0.0002

VAL 313 PRO 314 -0.0193

PRO 314 LYS 315 0.0000

LYS 315 LEU 316 0.0000

LEU 316 ASN 317 0.0004

ASN 317 ILE 318 -0.0001

ILE 318 PRO 319 0.0002

PRO 319 MET 320 0.0002

MET 320 GLY 321 0.0004

GLY 321 LEU 322 -0.0003

LEU 322 ASP 323 -0.0001

ASP 323 TRP 324 0.0001

TRP 324 THR 325 0.0002

THR 325 ASP 326 0.0000

ASP 326 GLU 327 0.0064

GLU 327 PHE 328 -0.0003

PHE 328 LEU 329 0.0001

LEU 329 MET 330 0.0003

MET 330 LYS 331 -0.0003

LYS 331 VAL 332 0.0001

VAL 332 SER 333 -0.0003

SER 333 GLU 334 0.0003

GLU 334 ILE 335 0.0002

ILE 335 SER 336 -0.0002

SER 336 GLY 337 0.0000

GLY 337 GLN 338 0.0002

GLN 338 PRO 339 -0.0001

PRO 339 ILE 340 -0.0160

ILE 340 PRO 341 0.0001

PRO 341 ALA 342 -0.0002

ALA 342 SER 343 -0.0001

SER 343 LEU 344 0.0003

LEU 344 THR 345 -0.0000

THR 345 LYS 346 -0.0004

LYS 346 GLU 347 -0.0002

GLU 347 ARG 348 -0.0001

ARG 348 GLY 349 -0.0002

GLY 349 ARG 350 -0.0005

ARG 350 LEU 351 0.0002

LEU 351 VAL 352 -0.0000

VAL 352 ASP 353 -0.0042

ASP 353 MET 354 -0.0001

MET 354 MET 355 0.0000

MET 355 THR 356 0.0001

THR 356 ASP 357 -0.0001

ASP 357 SER 358 0.0002

SER 358 HIS 359 -0.0003

HIS 359 THR 360 0.0003

THR 360 TRP 361 0.0006

TRP 361 LEU 362 0.0000

LEU 362 HIS 363 -0.0004

HIS 363 GLY 364 -0.0001

GLY 364 LYS 365 -0.0002

LYS 365 ARG 366 -0.0363

ARG 366 PHE 367 0.0002

PHE 367 ALA 368 -0.0001

ALA 368 LEU 369 -0.0000

LEU 369 TRP 370 0.0001

TRP 370 GLY 371 -0.0003

GLY 371 ASP 372 -0.0003

ASP 372 PRO 373 0.0001

PRO 373 ASP 374 0.0001

ASP 374 PHE 375 0.0000

PHE 375 VAL 376 -0.0002

VAL 376 MET 377 0.0004

MET 377 GLY 378 -0.0000

GLY 378 LEU 379 0.0003

LEU 379 VAL 380 0.0000

VAL 380 LYS 381 0.0002

LYS 381 PHE 382 0.0001

PHE 382 LEU 383 0.0001

LEU 383 LEU 384 0.0001

LEU 384 GLU 385 0.0000

GLU 385 LEU 386 -0.0003

LEU 386 GLY 387 0.0001

GLY 387 CYS 388 -0.0000

CYS 388 GLU 389 0.0002

GLU 389 PRO 390 0.0001

PRO 390 VAL 391 -0.0000

VAL 391 HIS 392 -0.0281

HIS 392 ILE 393 0.0001

ILE 393 LEU 394 0.0001

LEU 394 CYS 395 -0.0002

CYS 395 HIS 396 -0.0001

HIS 396 ASN 397 0.0000

ASN 397 GLY 398 -0.0000

GLY 398 ASN 399 -0.0001

ASN 399 LYS 400 0.0002

LYS 400 ARG 401 -0.0002

ARG 401 TRP 402 0.0001

TRP 402 LYS 403 -0.0001

LYS 403 LYS 404 -0.0005

LYS 404 ALA 405 0.0014

ALA 405 VAL 406 -0.0001

VAL 406 ASP 407 -0.0001

ASP 407 ALA 408 -0.0001

ALA 408 ILE 409 -0.0001

ILE 409 LEU 410 0.0001

LEU 410 ALA 411 -0.0001

ALA 411 ALA 412 -0.0000

ALA 412 SER 413 -0.0003

SER 413 PRO 414 0.0001

PRO 414 TYR 415 0.0002

TYR 415 GLY 416 -0.0000

GLY 416 LYS 417 0.0001

LYS 417 ASN 418 -0.0228

ASN 418 ALA 419 -0.0000

ALA 419 THR 420 -0.0004

THR 420 VAL 421 0.0005

VAL 421 TYR 422 -0.0001

TYR 422 ILE 423 -0.0002

ILE 423 GLY 424 0.0002

GLY 424 LYS 425 0.0003

LYS 425 ASP 426 -0.0001

ASP 426 LEU 427 0.0002

LEU 427 TRP 428 0.0001

TRP 428 HIS 429 0.0002

HIS 429 LEU 430 -0.0001

LEU 430 ARG 431 0.0073

ARG 431 SER 432 -0.0000

SER 432 LEU 433 0.0002

LEU 433 VAL 434 0.0003

VAL 434 PHE 435 -0.0000

PHE 435 THR 436 0.0002

THR 436 ASP 437 0.0002

ASP 437 LYS 438 0.0002

LYS 438 PRO 439 -0.0005

PRO 439 ASP 440 0.0003

ASP 440 PHE 441 0.0001

PHE 441 MET 442 -0.0002

MET 442 ILE 443 -0.0002

ILE 443 GLY 444 -0.0145

GLY 444 ASN 445 -0.0003

ASN 445 SER 446 0.0000

SER 446 TYR 447 -0.0004

TYR 447 GLY 448 -0.0004

GLY 448 LYS 449 0.0000

LYS 449 PHE 450 0.0001

PHE 450 ILE 451 0.0000

ILE 451 GLN 452 0.0000

GLN 452 ARG 453 -0.0003

ARG 453 ASP 454 -0.0002

ASP 454 THR 455 -0.0003

THR 455 LEU 456 -0.0001

LEU 456 HIS 457 0.0014

HIS 457 LYS 458 -0.0003

LYS 458 GLY 459 -0.0000

GLY 459 LYS 460 -0.0002

LYS 460 GLU 461 -0.0004

GLU 461 PHE 462 0.0004

PHE 462 GLU 463 0.0003

GLU 463 VAL 464 -0.0002

VAL 464 PRO 465 -0.0002

PRO 465 LEU 466 -0.0001

LEU 466 ILE 467 -0.0002

ILE 467 ARG 468 0.0001

ARG 468 ILE 469 -0.0002

ILE 469 GLY 470 -0.0111

GLY 470 PHE 471 0.0001

PHE 471 PRO 472 -0.0001

PRO 472 ILE 473 0.0002

ILE 473 PHE 474 -0.0004

PHE 474 ASP 475 0.0000

ASP 475 ARG 476 -0.0001

ARG 476 HIS 477 0.0001

HIS 477 HIS 478 -0.0002

HIS 478 LEU 479 0.0000

LEU 479 HIS 480 0.0004

HIS 480 ARG 481 -0.0002

ARG 481 SER 482 0.0002

SER 482 THR 483 0.0069

THR 483 THR 484 -0.0001

THR 484 LEU 485 0.0000

LEU 485 GLY 486 0.0002

GLY 486 TYR 487 -0.0000

TYR 487 GLU 488 -0.0003

GLU 488 GLY 489 0.0003

GLY 489 ALA 490 0.0004

ALA 490 MET 491 0.0002

MET 491 GLN 492 0.0000

GLN 492 ILE 493 0.0000

ILE 493 LEU 494 0.0000

LEU 494 THR 495 -0.0002

THR 495 THR 496 -0.0037

THR 496 LEU 497 0.0002

LEU 497 VAL 498 0.0003

VAL 498 ASN 499 0.0003

ASN 499 SER 500 -0.0005

SER 500 ILE 501 -0.0002

ILE 501 LEU 502 -0.0001

LEU 502 GLU 503 0.0001

GLU 503 ARG 504 -0.0000

ARG 504 LEU 505 -0.0004

LEU 505 ASP 506 -0.0002

ASP 506 GLU 507 -0.0001

GLU 507 GLU 508 -0.0000

GLU 508 THR 509 0.0239

THR 509 ARG 510 -0.0001

ARG 510 GLY 511 0.0002

GLY 511 MET 512 0.0003

MET 512 GLN 513 0.0001

GLN 513 ALA 514 0.0000

ALA 514 THR 515 -0.0004

THR 515 ASP 516 0.0000

ASP 516 TYR 517 -0.0002

TYR 517 ASN 518 0.0001

ASN 518 HIS 519 0.0001

HIS 519 ASP 520 0.0001

ASP 520 LEU 521 0.0003

LEU 521 VAL 522 -0.0006

VAL 522 ARG 523 0.0004

ARG 523 ALA 1 -0.0077

ALA 1 MET 2 0.0000

MET 2 ARG 3 0.0001

ARG 3 GLN 4 -0.0000

GLN 4 CYS 5 0.0001

CYS 5 ALA 6 -0.0001

ALA 6 ILE 7 -0.0001

ILE 7 TYR 8 0.0001

TYR 8 GLY 9 -0.0000

GLY 9 LYS 10 -0.0001

LYS 10 GLY 11 0.0002

GLY 11 GLY 12 0.0002

GLY 12 ILE 13 0.0002

ILE 13 GLY 14 0.0039

GLY 14 LYS 15 0.0001

LYS 15 SER 16 0.0000

SER 16 THR 17 -0.0001

THR 17 THR 18 0.0002

THR 18 THR 19 0.0001

THR 19 GLN 20 0.0001

GLN 20 ASN 21 0.0002

ASN 21 LEU 22 -0.0001

LEU 22 VAL 23 0.0001

VAL 23 ALA 24 0.0000

ALA 24 ALA 25 0.0002

ALA 25 LEU 26 0.0002

LEU 26 ALA 27 -0.0059

ALA 27 GLU 28 -0.0002

GLU 28 MET 29 -0.0001

MET 29 GLY 30 -0.0000

GLY 30 LYS 31 -0.0003

LYS 31 LYS 32 -0.0002

LYS 32 VAL 33 0.0001

VAL 33 MET 34 0.0001

MET 34 ILE 35 -0.0004

ILE 35 VAL 36 0.0003

VAL 36 GLY 37 -0.0000

GLY 37 CYS 38 0.0000

CYS 38 ASP 39 -0.0002

ASP 39 PRO 40 -0.0025

PRO 40 LYS 41 -0.0001

LYS 41 ALA 42 0.0001

ALA 42 ASP 43 -0.0001

ASP 43 SER 44 0.0002

SER 44 THR 45 0.0002

THR 45 ARG 46 0.0004

ARG 46 LEU 47 -0.0001

LEU 47 ILE 48 0.0000

ILE 48 LEU 49 -0.0001

LEU 49 HIS 50 0.0001

HIS 50 SER 51 -0.0001

SER 51 LYS 52 -0.0002

LYS 52 ALA 53 -0.0523

ALA 53 GLN 54 -0.0004

GLN 54 ASN 55 0.0004

ASN 55 THR 56 -0.0001

THR 56 ILE 57 -0.0001

ILE 57 MET 58 0.0004

MET 58 GLU 59 -0.0003

GLU 59 MET 60 0.0001

MET 60 ALA 61 -0.0001

ALA 61 ALA 62 0.0002

ALA 62 GLU 63 -0.0002

GLU 63 ALA 64 0.0002

ALA 64 GLY 65 0.0002

GLY 65 THR 66 -0.0070

THR 66 VAL 67 -0.0002

VAL 67 GLU 68 0.0002

GLU 68 ASP 69 -0.0000

ASP 69 LEU 70 -0.0004

LEU 70 GLU 71 0.0002

GLU 71 LEU 72 0.0002

LEU 72 GLU 73 -0.0000

GLU 73 ASP 74 0.0001

ASP 74 VAL 75 0.0002

VAL 75 LEU 76 -0.0000

LEU 76 LYS 77 0.0001

LYS 77 ALA 78 -0.0002

ALA 78 GLY 79 -0.0289

GLY 79 TYR 80 -0.0002

TYR 80 GLY 81 -0.0004

GLY 81 GLY 82 -0.0003

GLY 82 VAL 83 0.0001

VAL 83 LYS 84 0.0001

LYS 84 CYS 85 0.0002

CYS 85 VAL 86 -0.0001

VAL 86 GLU 87 -0.0002

GLU 87 SER 88 0.0002

SER 88 GLY 89 0.0001

GLY 89 GLY 90 -0.0001

GLY 90 PRO 91 0.0001

PRO 91 GLU 92 -0.0118

GLU 92 PRO 93 -0.0001

PRO 93 GLY 94 0.0000

GLY 94 VAL 95 0.0002

VAL 95 GLY 96 -0.0001

GLY 96 CYS 97 0.0004

CYS 97 ALA 98 -0.0004

ALA 98 GLY 99 0.0003

GLY 99 ARG 100 0.0001

ARG 100 GLY 101 0.0002

GLY 101 VAL 102 0.0001

VAL 102 ILE 103 0.0002

ILE 103 THR 104 0.0004

THR 104 ALA 105 0.0090

ALA 105 ILE 106 -0.0001

ILE 106 ASN 107 0.0001

ASN 107 PHE 108 -0.0002

PHE 108 LEU 109 -0.0001

LEU 109 GLU 110 0.0000

GLU 110 GLU 111 -0.0001

GLU 111 GLU 112 0.0001

GLU 112 GLY 113 -0.0000

GLY 113 ALA 114 0.0001

ALA 114 TYR 115 0.0002

TYR 115 GLU 116 0.0004

GLU 116 ASP 117 -0.0003

ASP 117 ASP 118 0.0001

ASP 118 LEU 119 -0.0000

LEU 119 ASP 120 -0.0001

ASP 120 PHE 121 0.0002

PHE 121 VAL 122 -0.0001

VAL 122 PHE 123 -0.0005

PHE 123 TYR 124 0.0004

TYR 124 ASP 125 -0.0004

ASP 125 VAL 126 0.0002

VAL 126 LEU 127 0.0000

LEU 127 GLY 128 -0.0000

GLY 128 ASP 129 -0.0002

ASP 129 VAL 130 -0.0000

VAL 130 VAL 131 0.0193

VAL 131 CYS 132 -0.0002

CYS 132 GLY 133 0.0005

GLY 133 GLY 134 0.0002

GLY 134 PHE 135 -0.0004

PHE 135 ALA 136 -0.0001

ALA 136 MET 137 -0.0001

MET 137 PRO 138 -0.0003

PRO 138 ILE 139 0.0001

ILE 139 ARG 140 0.0003

ARG 140 GLU 141 -0.0003

GLU 141 ASN 142 -0.0004

ASN 142 LYS 143 -0.0003

LYS 143 ALA 144 -0.0042

ALA 144 GLN 145 0.0003

GLN 145 GLU 146 0.0000

GLU 146 ILE 147 -0.0001

ILE 147 TYR 148 0.0001

TYR 148 ILE 149 0.0000

ILE 149 VAL 150 -0.0001

VAL 150 CYS 151 -0.0000

CYS 151 SER 152 -0.0001

SER 152 GLY 153 -0.0001

GLY 153 GLU 154 0.0003

GLU 154 MET 155 0.0001

MET 155 MET 156 0.0002

MET 156 ALA 157 -0.0036

ALA 157 MET 158 0.0002

MET 158 TYR 159 -0.0002

TYR 159 ALA 160 -0.0001

ALA 160 ALA 161 0.0004

ALA 161 ASN 162 0.0001

ASN 162 ASN 163 0.0002

ASN 163 ILE 164 -0.0005

ILE 164 SER 165 -0.0001

SER 165 LYS 166 0.0004

LYS 166 GLY 167 0.0004

GLY 167 ILE 168 -0.0004

ILE 168 VAL 169 0.0002

VAL 169 LYS 170 -0.0092

LYS 170 TYR 171 -0.0004

TYR 171 ALA 172 0.0002

ALA 172 ASN 173 0.0003

ASN 173 SER 174 -0.0001

SER 174 GLY 175 -0.0001

GLY 175 SER 176 -0.0000

SER 176 VAL 177 0.0001

VAL 177 ARG 178 -0.0002

ARG 178 LEU 179 0.0002

LEU 179 GLY 180 0.0004

GLY 180 GLY 181 -0.0002

GLY 181 LEU 182 -0.0003

LEU 182 ILE 183 0.0070

ILE 183 CYS 184 0.0002

CYS 184 ASN 185 -0.0003

ASN 185 SER 186 0.0000

SER 186 ARG 187 -0.0004

ARG 187 ASN 188 -0.0002

ASN 188 THR 189 -0.0002

THR 189 ASP 190 -0.0001

ASP 190 ARG 191 -0.0000

ARG 191 GLU 192 -0.0001

GLU 192 ASP 193 -0.0003

ASP 193 GLU 194 0.0004

GLU 194 LEU 195 -0.0003

LEU 195 ILE 196 0.0004

ILE 196 ILE 197 -0.0001

ILE 197 ALA 198 -0.0003

ALA 198 LEU 199 -0.0002

LEU 199 ALA 200 -0.0002

ALA 200 ASN 201 -0.0003

ASN 201 LYS 202 -0.0000

LYS 202 LEU 203 0.0002

LEU 203 GLY 204 0.0002

GLY 204 THR 205 0.0001

THR 205 GLN 206 -0.0001

GLN 206 MET 207 -0.0004

MET 207 ILE 208 -0.0002

ILE 208 HIS 209 0.0026

HIS 209 PHE 210 -0.0002

PHE 210 VAL 211 0.0004

VAL 211 PRO 212 0.0001

PRO 212 ARG 213 0.0003

ARG 213 ASP 214 -0.0003

ASP 214 ASN 215 0.0004

ASN 215 VAL 216 -0.0003

VAL 216 VAL 217 -0.0002

VAL 217 GLN 218 0.0000

GLN 218 ARG 219 0.0001

ARG 219 ALA 220 0.0003

ALA 220 GLU 221 0.0000

GLU 221 ILE 222 -0.0023

ILE 222 ARG 223 -0.0000

ARG 223 ARG 224 0.0001

ARG 224 MET 225 0.0005

MET 225 THR 226 -0.0002

THR 226 VAL 227 0.0003

VAL 227 ILE 228 -0.0000

ILE 228 GLU 229 0.0002

GLU 229 TYR 230 -0.0001

TYR 230 ASP 231 -0.0001

ASP 231 PRO 232 0.0002

PRO 232 LYS 233 0.0000

LYS 233 ALA 234 0.0006

ALA 234 LYS 235 0.0014

LYS 235 GLN 236 0.0001

GLN 236 ALA 237 0.0001

ALA 237 ASP 238 -0.0001

ASP 238 GLU 239 -0.0003

GLU 239 TYR 240 -0.0004

TYR 240 ARG 241 -0.0001

ARG 241 ALA 242 0.0000

ALA 242 LEU 243 -0.0000

LEU 243 ALA 244 0.0003

ALA 244 ARG 245 -0.0002

ARG 245 LYS 246 0.0002

LYS 246 VAL 247 0.0001

VAL 247 VAL 248 -0.0013

VAL 248 ASP 249 -0.0003

ASP 249 ASN 250 0.0004

ASN 250 LYS 251 -0.0000

LYS 251 LEU 252 -0.0001

LEU 252 LEU 253 -0.0001

LEU 253 VAL 254 -0.0000

VAL 254 ILE 255 0.0002

ILE 255 PRO 256 0.0001

PRO 256 ASN 257 0.0002

ASN 257 PRO 258 0.0005

PRO 258 ILE 259 -0.0004

ILE 259 THR 260 0.0003

THR 260 MET 261 -0.0033

MET 261 ASP 262 0.0002

ASP 262 GLU 263 0.0002

GLU 263 LEU 264 0.0001

LEU 264 GLU 265 0.0002

GLU 265 GLU 266 0.0002

GLU 266 LEU 267 0.0000

LEU 267 LEU 268 0.0001

LEU 268 MET 269 0.0002

MET 269 GLU 270 -0.0002

GLU 270 PHE 271 0.0000

PHE 271 ALA 1 -0.0010

ALA 1 MET 2 -0.0001

MET 2 ARG 3 0.0004

ARG 3 GLN 4 0.0001

GLN 4 CYS 5 0.0001

CYS 5 ALA 6 0.0001

ALA 6 ILE 7 -0.0001

ILE 7 TYR 8 0.0001

TYR 8 GLY 9 -0.0001

GLY 9 LYS 10 -0.0002

LYS 10 GLY 11 -0.0001

GLY 11 GLY 12 -0.0003

GLY 12 ILE 13 -0.0001

ILE 13 GLY 14 -0.0043

GLY 14 LYS 15 -0.0005

LYS 15 SER 16 -0.0001

SER 16 THR 17 -0.0002

THR 17 THR 18 0.0001

THR 18 THR 19 -0.0000

THR 19 GLN 20 -0.0003

GLN 20 ASN 21 -0.0002

ASN 21 LEU 22 -0.0004

LEU 22 VAL 23 -0.0003

VAL 23 ALA 24 0.0001

ALA 24 ALA 25 0.0003

ALA 25 LEU 26 -0.0005

LEU 26 ALA 27 0.0048

ALA 27 GLU 28 0.0003

GLU 28 MET 29 -0.0002

MET 29 GLY 30 0.0000

GLY 30 LYS 31 0.0001

LYS 31 LYS 32 -0.0002

LYS 32 VAL 33 0.0004

VAL 33 MET 34 -0.0001

MET 34 ILE 35 -0.0002

ILE 35 VAL 36 0.0001

VAL 36 GLY 37 0.0001

GLY 37 CYS 38 -0.0001

CYS 38 ASP 39 0.0003

ASP 39 PRO 40 0.0020

PRO 40 LYS 41 -0.0002

LYS 41 ALA 42 -0.0002

ALA 42 ASP 43 0.0000

ASP 43 SER 44 0.0002

SER 44 THR 45 0.0002

THR 45 ARG 46 0.0001

ARG 46 LEU 47 0.0005

LEU 47 ILE 48 0.0001

ILE 48 LEU 49 0.0002

LEU 49 HIS 50 0.0003

HIS 50 SER 51 -0.0003

SER 51 LYS 52 0.0002

LYS 52 ALA 53 0.0573

ALA 53 GLN 54 -0.0001

GLN 54 ASN 55 -0.0002

ASN 55 THR 56 0.0001

THR 56 ILE 57 -0.0000

ILE 57 MET 58 0.0002

MET 58 GLU 59 -0.0003

GLU 59 MET 60 0.0002

MET 60 ALA 61 0.0000

ALA 61 ALA 62 -0.0002

ALA 62 GLU 63 0.0003

GLU 63 ALA 64 -0.0001

ALA 64 GLY 65 -0.0001

GLY 65 THR 66 -0.0106

THR 66 VAL 67 -0.0001

VAL 67 GLU 68 -0.0001

GLU 68 ASP 69 -0.0000

ASP 69 LEU 70 -0.0005

LEU 70 GLU 71 0.0004

GLU 71 LEU 72 -0.0003

LEU 72 GLU 73 -0.0001

GLU 73 ASP 74 -0.0003

ASP 74 VAL 75 -0.0002

VAL 75 LEU 76 -0.0005

LEU 76 LYS 77 -0.0001

LYS 77 ALA 78 0.0001

ALA 78 GLY 79 0.0196

GLY 79 TYR 80 0.0002

TYR 80 GLY 81 0.0001

GLY 81 GLY 82 0.0002

GLY 82 VAL 83 0.0001

VAL 83 LYS 84 -0.0004

LYS 84 CYS 85 0.0001

CYS 85 VAL 86 0.0002

VAL 86 GLU 87 -0.0002

GLU 87 SER 88 -0.0000

SER 88 GLY 89 0.0004

GLY 89 GLY 90 -0.0004

GLY 90 PRO 91 -0.0002

PRO 91 GLU 92 0.0195

GLU 92 PRO 93 0.0003

PRO 93 GLY 94 0.0000

GLY 94 VAL 95 -0.0002

VAL 95 GLY 96 -0.0000

GLY 96 CYS 97 -0.0001

CYS 97 ALA 98 -0.0003

ALA 98 GLY 99 -0.0001

GLY 99 ARG 100 0.0001

ARG 100 GLY 101 0.0001

GLY 101 VAL 102 -0.0002

VAL 102 ILE 103 0.0000

ILE 103 THR 104 0.0002

THR 104 ALA 105 -0.0095

ALA 105 ILE 106 0.0001

ILE 106 ASN 107 0.0000

ASN 107 PHE 108 -0.0003

PHE 108 LEU 109 -0.0001

LEU 109 GLU 110 0.0001

GLU 110 GLU 111 -0.0003

GLU 111 GLU 112 -0.0001

GLU 112 GLY 113 -0.0003

GLY 113 ALA 114 0.0003

ALA 114 TYR 115 0.0000

TYR 115 GLU 116 0.0002

GLU 116 ASP 117 -0.0002

ASP 117 ASP 118 0.0028

ASP 118 LEU 119 -0.0004

LEU 119 ASP 120 -0.0001

ASP 120 PHE 121 0.0003

PHE 121 VAL 122 -0.0001

VAL 122 PHE 123 0.0001

PHE 123 TYR 124 0.0000

TYR 124 ASP 125 0.0000

ASP 125 VAL 126 -0.0003

VAL 126 LEU 127 0.0003

LEU 127 GLY 128 -0.0000

GLY 128 ASP 129 0.0001

ASP 129 VAL 130 -0.0004

VAL 130 VAL 131 -0.0091

VAL 131 CYS 132 0.0002

CYS 132 GLY 133 0.0001

GLY 133 GLY 134 0.0002

GLY 134 PHE 135 -0.0005

PHE 135 ALA 136 0.0001

ALA 136 MET 137 0.0003

MET 137 PRO 138 -0.0002

PRO 138 ILE 139 0.0000

ILE 139 ARG 140 -0.0002

ARG 140 GLU 141 0.0003

GLU 141 ASN 142 0.0002

ASN 142 LYS 143 -0.0000

LYS 143 ALA 144 0.0216

ALA 144 GLN 145 -0.0000

GLN 145 GLU 146 -0.0001

GLU 146 ILE 147 -0.0002

ILE 147 TYR 148 -0.0002

TYR 148 ILE 149 0.0003

ILE 149 VAL 150 -0.0001

VAL 150 CYS 151 0.0003

CYS 151 SER 152 0.0002

SER 152 GLY 153 -0.0002

GLY 153 GLU 154 -0.0001

GLU 154 MET 155 -0.0001

MET 155 MET 156 -0.0000

MET 156 ALA 157 -0.0011

ALA 157 MET 158 -0.0003

MET 158 TYR 159 -0.0001

TYR 159 ALA 160 -0.0002

ALA 160 ALA 161 0.0002

ALA 161 ASN 162 -0.0002

ASN 162 ASN 163 -0.0002

ASN 163 ILE 164 0.0003

ILE 164 SER 165 0.0003

SER 165 LYS 166 0.0002

LYS 166 GLY 167 0.0002

GLY 167 ILE 168 -0.0002

ILE 168 VAL 169 -0.0000

VAL 169 LYS 170 -0.0008

LYS 170 TYR 171 -0.0002

TYR 171 ALA 172 -0.0000

ALA 172 ASN 173 -0.0000

ASN 173 SER 174 -0.0001

SER 174 GLY 175 -0.0002

GLY 175 SER 176 0.0003

SER 176 VAL 177 0.0001

VAL 177 ARG 178 0.0001

ARG 178 LEU 179 -0.0001

LEU 179 GLY 180 0.0005

GLY 180 GLY 181 -0.0002

GLY 181 LEU 182 -0.0001

LEU 182 ILE 183 -0.0155

ILE 183 CYS 184 0.0002

CYS 184 ASN 185 -0.0001

ASN 185 SER 186 -0.0001

SER 186 ARG 187 0.0000

ARG 187 ASN 188 0.0001

ASN 188 THR 189 0.0001

THR 189 ASP 190 0.0001

ASP 190 ARG 191 -0.0001

ARG 191 GLU 192 -0.0001

GLU 192 ASP 193 0.0001

ASP 193 GLU 194 0.0002

GLU 194 LEU 195 0.0003

LEU 195 ILE 196 -0.0016

ILE 196 ILE 197 0.0002

ILE 197 ALA 198 -0.0003

ALA 198 LEU 199 0.0003

LEU 199 ALA 200 0.0001

ALA 200 ASN 201 -0.0000

ASN 201 LYS 202 -0.0001

LYS 202 LEU 203 0.0001

LEU 203 GLY 204 0.0000

GLY 204 THR 205 -0.0000

THR 205 GLN 206 0.0000

GLN 206 MET 207 -0.0002

MET 207 ILE 208 0.0002

ILE 208 HIS 209 -0.0046

HIS 209 PHE 210 0.0000

PHE 210 VAL 211 -0.0000

VAL 211 PRO 212 0.0001

PRO 212 ARG 213 0.0001

ARG 213 ASP 214 -0.0003

ASP 214 ASN 215 -0.0001

ASN 215 VAL 216 -0.0001

VAL 216 VAL 217 -0.0001

VAL 217 GLN 218 0.0001

GLN 218 ARG 219 -0.0002

ARG 219 ALA 220 0.0001

ALA 220 GLU 221 -0.0001

GLU 221 ILE 222 0.0024

ILE 222 ARG 223 0.0003

ARG 223 ARG 224 0.0005

ARG 224 MET 225 0.0000

MET 225 THR 226 -0.0002

THR 226 VAL 227 0.0002

VAL 227 ILE 228 -0.0001

ILE 228 GLU 229 -0.0001

GLU 229 TYR 230 -0.0000

TYR 230 ASP 231 -0.0005

ASP 231 PRO 232 0.0001

PRO 232 LYS 233 -0.0000

LYS 233 ALA 234 0.0001

ALA 234 LYS 235 -0.0008

LYS 235 GLN 236 -0.0002

GLN 236 ALA 237 0.0002

ALA 237 ASP 238 -0.0000

ASP 238 GLU 239 -0.0003

GLU 239 TYR 240 -0.0001

TYR 240 ARG 241 0.0002

ARG 241 ALA 242 0.0000

ALA 242 LEU 243 0.0002

LEU 243 ALA 244 -0.0000

ALA 244 ARG 245 0.0001

ARG 245 LYS 246 -0.0002

LYS 246 VAL 247 -0.0000

VAL 247 VAL 248 0.0018

VAL 248 ASP 249 0.0002

ASP 249 ASN 250 -0.0003

ASN 250 LYS 251 -0.0001

LYS 251 LEU 252 0.0001

LEU 252 LEU 253 0.0004

LEU 253 VAL 254 0.0001

VAL 254 ILE 255 0.0004

ILE 255 PRO 256 -0.0003

PRO 256 ASN 257 -0.0000

ASN 257 PRO 258 0.0000

PRO 258 ILE 259 0.0002

ILE 259 THR 260 0.0002

THR 260 MET 261 0.0001

MET 261 ASP 262 -0.0001

ASP 262 GLU 263 -0.0001

GLU 263 LEU 264 -0.0001

LEU 264 GLU 265 0.0002

GLU 265 GLU 266 -0.0001

GLU 266 LEU 267 0.0002

LEU 267 LEU 268 -0.0001

LEU 268 MET 269 -0.0001

MET 269 GLU 270 0.0001

GLU 270 PHE 271 -0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** doused_J6172_17 ***

CA strain for 2602182336223344808

--- normal mode 7 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* doused_J6172_17 *