Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* doused_J6172_17 *

CA strain for 2602182336223344808

--- normal mode 8 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
SER 5 ARG 6 0.0002

ARG 6 GLU 7 -0.0004

GLU 7 GLU 8 -0.0001

GLU 8 VAL 9 0.0001

VAL 9 GLU 10 0.0002

GLU 10 SER 11 -0.0005

SER 11 LEU 12 0.0000

LEU 12 ILE 13 -0.0001

ILE 13 GLN 14 0.0001

GLN 14 GLU 15 -0.0001

GLU 15 VAL 16 -0.0002

VAL 16 LEU 17 -0.0001

LEU 17 GLU 18 -0.0003

GLU 18 VAL 19 0.0001

VAL 19 TYR 20 0.0001

TYR 20 PRO 21 0.0003

PRO 21 GLU 22 -0.0003

GLU 22 LYS 23 0.0002

LYS 23 ALA 24 -0.0001

ALA 24 ARG 25 0.0002

ARG 25 LYS 26 0.0002

LYS 26 ASP 27 -0.0002

ASP 27 ARG 28 -0.0000

ARG 28 ASN 29 -0.0000

ASN 29 LYS 30 -0.0006

LYS 30 HIS 31 -0.0026

HIS 31 LEU 32 -0.0002

LEU 32 ALA 33 0.0002

ALA 33 VAL 34 -0.0002

VAL 34 ASN 35 0.0001

ASN 35 ASP 36 -0.0001

ASP 36 PRO 37 -0.0001

PRO 37 ALA 38 -0.0003

ALA 38 VAL 39 -0.0004

VAL 39 THR 40 0.0001

THR 40 GLN 41 -0.0001

GLN 41 SER 42 -0.0000

SER 42 LYS 43 -0.0000

LYS 43 LYS 44 0.0000

LYS 44 CYS 45 0.0001

CYS 45 ILE 46 -0.0001

ILE 46 ILE 47 0.0001

ILE 47 SER 48 -0.0001

SER 48 ASN 49 0.0001

ASN 49 LYS 50 -0.0001

LYS 50 LYS 51 -0.0001

LYS 51 SER 52 0.0001

SER 52 GLN 53 -0.0001

GLN 53 PRO 54 0.0003

PRO 54 GLY 55 -0.0002

GLY 55 LEU 56 0.0001

LEU 56 MET 57 0.0009

MET 57 THR 58 -0.0000

THR 58 ILE 59 0.0000

ILE 59 ARG 60 0.0002

ARG 60 GLY 61 0.0005

GLY 61 CYS 62 -0.0000

CYS 62 ALA 63 -0.0002

ALA 63 TYR 64 0.0004

TYR 64 ALA 65 0.0001

ALA 65 GLY 66 0.0004

GLY 66 SER 67 0.0002

SER 67 LYS 68 -0.0000

LYS 68 GLY 69 0.0005

GLY 69 VAL 70 0.0018

VAL 70 VAL 71 0.0003

VAL 71 TRP 72 0.0001

TRP 72 GLY 73 -0.0001

GLY 73 PRO 74 0.0004

PRO 74 ILE 75 0.0004

ILE 75 LYS 76 -0.0001

LYS 76 ASP 77 -0.0003

ASP 77 MET 78 -0.0000

MET 78 ILE 79 -0.0003

ILE 79 HIS 80 0.0003

HIS 80 ILE 81 0.0000

ILE 81 SER 82 0.0002

SER 82 HIS 83 0.0182

HIS 83 GLY 84 0.0002

GLY 84 PRO 85 0.0004

PRO 85 VAL 86 -0.0000

VAL 86 GLY 87 -0.0001

GLY 87 CYS 88 -0.0003

CYS 88 GLY 89 0.0000

GLY 89 GLN 90 -0.0002

GLN 90 TYR 91 0.0003

TYR 91 SER 92 0.0003

SER 92 ARG 93 -0.0001

ARG 93 ALA 94 -0.0003

ALA 94 GLY 95 0.0001

GLY 95 ARG 96 0.0137

ARG 96 ARG 97 0.0001

ARG 97 ASN 98 -0.0000

ASN 98 TYR 99 -0.0000

TYR 99 TYR 100 -0.0000

TYR 100 ILE 101 -0.0000

ILE 101 GLY 102 -0.0000

GLY 102 THR 103 -0.0001

THR 103 THR 104 0.0001

THR 104 GLY 105 0.0000

GLY 105 VAL 106 -0.0001

VAL 106 ASN 107 -0.0000

ASN 107 ALA 108 0.0001

ALA 108 PHE 109 0.0002

PHE 109 VAL 110 -0.0003

VAL 110 THR 111 -0.0004

THR 111 MET 112 0.0001

MET 112 ASN 113 0.0000

ASN 113 PHE 114 -0.0002

PHE 114 THR 115 0.0001

THR 115 SER 116 0.0003

SER 116 ASP 117 -0.0002

ASP 117 PHE 118 -0.0001

PHE 118 GLN 119 0.0004

GLN 119 GLU 120 -0.0003

GLU 120 LYS 121 0.0001

LYS 121 ASP 122 0.0207

ASP 122 ILE 123 -0.0002

ILE 123 VAL 124 0.0002

VAL 124 PHE 125 0.0001

PHE 125 GLY 126 0.0001

GLY 126 GLY 127 -0.0000

GLY 127 ASP 128 -0.0002

ASP 128 LYS 129 -0.0003

LYS 129 LYS 130 0.0003

LYS 130 LEU 131 -0.0001

LEU 131 ALA 132 0.0001

ALA 132 LYS 133 -0.0002

LYS 133 LEU 134 -0.0003

LEU 134 ILE 135 0.0042

ILE 135 ASP 136 -0.0002

ASP 136 GLU 137 -0.0001

GLU 137 VAL 138 0.0004

VAL 138 GLU 139 0.0001

GLU 139 THR 140 -0.0003

THR 140 LEU 141 -0.0000

LEU 141 PHE 142 0.0000

PHE 142 PRO 143 -0.0001

PRO 143 LEU 144 0.0000

LEU 144 ASN 145 -0.0001

ASN 145 LYS 146 -0.0001

LYS 146 GLY 147 -0.0004

GLY 147 ILE 148 -0.0223

ILE 148 SER 149 -0.0001

SER 149 VAL 150 -0.0002

VAL 150 GLN 151 -0.0002

GLN 151 SER 152 0.0001

SER 152 GLU 153 -0.0001

GLU 153 CYS 154 0.0000

CYS 154 PRO 155 0.0003

PRO 155 ILE 156 0.0001

ILE 156 GLY 157 0.0002

GLY 157 LEU 158 0.0000

LEU 158 ILE 159 0.0003

ILE 159 GLY 160 0.0001

GLY 160 ASP 161 0.0292

ASP 161 ASP 162 0.0000

ASP 162 ILE 163 -0.0001

ILE 163 GLU 164 0.0003

GLU 164 SER 165 0.0004

SER 165 VAL 166 -0.0002

VAL 166 SER 167 0.0001

SER 167 LYS 168 0.0002

LYS 168 VAL 169 -0.0003

VAL 169 LYS 170 0.0000

LYS 170 GLY 171 0.0002

GLY 171 ALA 172 0.0000

ALA 172 GLU 173 0.0001

GLU 173 LEU 174 -0.0173

LEU 174 SER 175 0.0003

SER 175 LYS 176 -0.0001

LYS 176 THR 177 0.0002

THR 177 ILE 178 0.0000

ILE 178 VAL 179 -0.0002

VAL 179 PRO 180 0.0001

PRO 180 VAL 181 -0.0002

VAL 181 ARG 182 -0.0001

ARG 182 CYS 183 0.0002

CYS 183 GLU 184 0.0001

GLU 184 GLY 185 -0.0001

GLY 185 PHE 186 -0.0002

PHE 186 ARG 187 -0.0129

ARG 187 GLY 188 0.0002

GLY 188 VAL 189 0.0002

VAL 189 SER 190 -0.0001

SER 190 GLN 191 -0.0001

GLN 191 SER 192 -0.0001

SER 192 LEU 193 0.0002

LEU 193 GLY 194 0.0004

GLY 194 HIS 195 -0.0001

HIS 195 HIS 196 0.0002

HIS 196 ILE 197 -0.0000

ILE 197 ALA 198 0.0000

ALA 198 ASN 199 0.0000

ASN 199 ASP 200 0.0097

ASP 200 ALA 201 0.0003

ALA 201 VAL 202 0.0002

VAL 202 ARG 203 -0.0001

ARG 203 ASP 204 -0.0004

ASP 204 TRP 205 0.0004

TRP 205 VAL 206 -0.0002

VAL 206 LEU 207 0.0001

LEU 207 GLY 208 -0.0001

GLY 208 LYS 209 0.0003

LYS 209 ARG 210 0.0002

ARG 210 ASP 211 -0.0003

ASP 211 GLU 212 -0.0002

GLU 212 ASP 213 0.0022

ASP 213 THR 214 -0.0001

THR 214 THR 215 0.0001

THR 215 PHE 216 0.0002

PHE 216 ALA 217 -0.0001

ALA 217 SER 218 0.0001

SER 218 THR 219 -0.0000

THR 219 PRO 220 -0.0002

PRO 220 TYR 221 0.0003

TYR 221 ASP 222 -0.0001

ASP 222 VAL 223 0.0002

VAL 223 ALA 224 0.0001

ALA 224 ILE 225 -0.0000

ILE 225 ILE 226 0.0005

ILE 226 GLY 227 -0.0000

GLY 227 ASP 228 -0.0002

ASP 228 TYR 229 0.0002

TYR 229 ASN 230 0.0001

ASN 230 ILE 231 -0.0000

ILE 231 GLY 232 0.0002

GLY 232 GLY 233 0.0002

GLY 233 ASP 234 0.0001

ASP 234 ALA 235 -0.0001

ALA 235 TRP 236 -0.0003

TRP 236 SER 237 0.0003

SER 237 SER 238 -0.0002

SER 238 ARG 239 0.0005

ARG 239 ILE 240 -0.0003

ILE 240 LEU 241 0.0001

LEU 241 LEU 242 -0.0001

LEU 242 GLU 243 -0.0004

GLU 243 GLU 244 0.0000

GLU 244 MET 245 0.0000

MET 245 GLY 246 -0.0002

GLY 246 LEU 247 -0.0001

LEU 247 ARG 248 -0.0002

ARG 248 CYS 249 0.0000

CYS 249 VAL 250 0.0002

VAL 250 ALA 251 0.0000

ALA 251 GLN 252 0.0022

GLN 252 TRP 253 0.0003

TRP 253 SER 254 -0.0001

SER 254 GLY 255 0.0001

GLY 255 ASP 256 -0.0002

ASP 256 GLY 257 -0.0001

GLY 257 SER 258 0.0001

SER 258 ILE 259 -0.0004

ILE 259 SER 260 0.0001

SER 260 GLU 261 0.0001

GLU 261 ILE 262 -0.0001

ILE 262 GLU 263 0.0001

GLU 263 LEU 264 0.0001

LEU 264 THR 265 0.0086

THR 265 PRO 266 0.0004

PRO 266 LYS 267 -0.0002

LYS 267 VAL 268 0.0001

VAL 268 LYS 269 -0.0001

LYS 269 LEU 270 0.0001

LEU 270 ASN 271 -0.0003

ASN 271 LEU 272 -0.0001

LEU 272 VAL 273 -0.0001

VAL 273 HIS 274 0.0004

HIS 274 CYS 275 0.0000

CYS 275 TYR 276 -0.0002

TYR 276 ARG 277 0.0002

ARG 277 SER 278 0.0001

SER 278 MET 279 0.0002

MET 279 ASN 280 0.0005

ASN 280 TYR 281 0.0001

TYR 281 ILE 282 0.0002

ILE 282 SER 283 0.0003

SER 283 ARG 284 0.0000

ARG 284 HIS 285 -0.0002

HIS 285 MET 286 0.0002

MET 286 GLU 287 0.0000

GLU 287 GLU 288 0.0001

GLU 288 LYS 289 0.0001

LYS 289 TYR 290 0.0000

TYR 290 GLY 291 0.0012

GLY 291 ILE 292 0.0004

ILE 292 PRO 293 0.0001

PRO 293 TRP 294 0.0001

TRP 294 MET 295 0.0002

MET 295 GLU 296 -0.0002

GLU 296 TYR 297 0.0002

TYR 297 ASN 298 -0.0000

ASN 298 PHE 299 0.0001

PHE 299 PHE 300 0.0002

PHE 300 GLY 301 -0.0005

GLY 301 PRO 302 0.0000

PRO 302 THR 303 -0.0001

THR 303 LYS 304 0.0002

LYS 304 THR 305 -0.0002

THR 305 ILE 306 -0.0004

ILE 306 GLU 307 0.0001

GLU 307 SER 308 -0.0001

SER 308 LEU 309 0.0003

LEU 309 ARG 310 0.0002

ARG 310 ALA 311 -0.0003

ALA 311 ILE 312 -0.0001

ILE 312 ALA 313 0.0001

ALA 313 ALA 314 -0.0001

ALA 314 LYS 315 0.0003

LYS 315 PHE 316 0.0002

PHE 316 ASP 317 0.0001

ASP 317 GLU 318 0.0002

GLU 318 SER 319 0.0001

SER 319 ILE 320 -0.0001

ILE 320 GLN 321 0.0004

GLN 321 LYS 322 0.0000

LYS 322 LYS 323 -0.0002

LYS 323 CYS 324 0.0004

CYS 324 GLU 325 0.0001

GLU 325 GLU 326 -0.0000

GLU 326 VAL 327 0.0000

VAL 327 ILE 328 -0.0000

ILE 328 ALA 329 -0.0001

ALA 329 LYS 330 -0.0004

LYS 330 TYR 331 0.0001

TYR 331 LYS 332 0.0002

LYS 332 PRO 333 0.0004

PRO 333 GLU 334 -0.0002

GLU 334 TRP 335 -0.0001

TRP 335 GLU 336 0.0001

GLU 336 ALA 337 0.0003

ALA 337 VAL 338 0.0002

VAL 338 VAL 339 -0.0001

VAL 339 ALA 340 -0.0002

ALA 340 LYS 341 0.0003

LYS 341 TYR 342 -0.0001

TYR 342 ARG 343 0.0062

ARG 343 PRO 344 0.0002

PRO 344 ARG 345 -0.0001

ARG 345 LEU 346 -0.0004

LEU 346 GLU 347 -0.0001

GLU 347 GLY 348 -0.0001

GLY 348 LYS 349 0.0003

LYS 349 ARG 350 0.0001

ARG 350 VAL 351 -0.0005

VAL 351 MET 352 0.0003

MET 352 LEU 353 -0.0001

LEU 353 TYR 354 0.0002

TYR 354 ILE 355 -0.0002

ILE 355 GLY 356 0.0022

GLY 356 GLY 357 0.0002

GLY 357 LEU 358 0.0004

LEU 358 ARG 359 -0.0001

ARG 359 PRO 360 -0.0001

PRO 360 ARG 361 -0.0001

ARG 361 HIS 362 -0.0003

HIS 362 VAL 363 -0.0002

VAL 363 ILE 364 0.0003

ILE 364 GLY 365 -0.0001

GLY 365 ALA 366 -0.0003

ALA 366 TYR 367 0.0002

TYR 367 GLU 368 0.0001

GLU 368 ASP 369 -0.0012

ASP 369 LEU 370 0.0002

LEU 370 GLY 371 0.0000

GLY 371 MET 372 0.0002

MET 372 GLU 373 0.0000

GLU 373 VAL 374 0.0000

VAL 374 VAL 375 0.0003

VAL 375 GLY 376 0.0000

GLY 376 THR 377 -0.0000

THR 377 GLY 378 0.0003

GLY 378 TYR 379 -0.0004

TYR 379 GLU 380 -0.0001

GLU 380 PHE 381 -0.0002

PHE 381 ALA 382 0.0052

ALA 382 HIS 383 0.0001

HIS 383 ASN 384 -0.0002

ASN 384 ASP 385 -0.0001

ASP 385 ASP 386 -0.0001

ASP 386 TYR 387 -0.0001

TYR 387 ASP 388 0.0004

ASP 388 ARG 389 0.0002

ARG 389 THR 390 -0.0001

THR 390 MET 391 -0.0002

MET 391 LYS 392 0.0004

LYS 392 GLU 393 0.0001

GLU 393 MET 394 -0.0005

MET 394 GLY 395 0.0045

GLY 395 ASP 396 -0.0000

ASP 396 SER 397 -0.0003

SER 397 THR 398 -0.0005

THR 398 LEU 399 0.0003

LEU 399 LEU 400 -0.0002

LEU 400 TYR 401 0.0000

TYR 401 ASP 402 -0.0000

ASP 402 ASP 403 -0.0002

ASP 403 VAL 404 0.0001

VAL 404 THR 405 0.0002

THR 405 GLY 406 -0.0005

GLY 406 TYR 407 -0.0001

TYR 407 GLU 408 -0.0019

GLU 408 PHE 409 0.0003

PHE 409 GLU 410 -0.0003

GLU 410 GLU 411 -0.0000

GLU 411 PHE 412 -0.0004

PHE 412 VAL 413 0.0001

VAL 413 LYS 414 0.0002

LYS 414 ARG 415 -0.0002

ARG 415 ILE 416 0.0003

ILE 416 LYS 417 -0.0001

LYS 417 PRO 418 0.0001

PRO 418 ASP 419 0.0002

ASP 419 LEU 420 0.0001

LEU 420 ILE 421 -0.0021

ILE 421 GLY 422 -0.0003

GLY 422 SER 423 0.0002

SER 423 GLY 424 -0.0000

GLY 424 ILE 425 0.0001

ILE 425 LYS 426 0.0000

LYS 426 GLU 427 0.0003

GLU 427 LYS 428 -0.0001

LYS 428 PHE 429 0.0000

PHE 429 ILE 430 -0.0002

ILE 430 PHE 431 -0.0001

PHE 431 GLN 432 0.0000

GLN 432 LYS 433 -0.0003

LYS 433 MET 434 -0.0020

MET 434 GLY 435 -0.0002

GLY 435 ILE 436 0.0003

ILE 436 PRO 437 0.0001

PRO 437 PHE 438 -0.0000

PHE 438 ARG 439 -0.0000

ARG 439 GLU 440 -0.0001

GLU 440 MET 441 0.0002

MET 441 HIS 442 -0.0002

HIS 442 SER 443 -0.0000

SER 443 TRP 444 -0.0002

TRP 444 ASP 445 0.0002

ASP 445 TYR 446 -0.0002

TYR 446 SER 447 0.0030

SER 447 GLY 448 0.0002

GLY 448 PRO 449 0.0000

PRO 449 TYR 450 -0.0003

TYR 450 HIS 451 -0.0000

HIS 451 GLY 452 0.0000

GLY 452 PHE 453 0.0001

PHE 453 ASP 454 -0.0004

ASP 454 GLY 455 -0.0001

GLY 455 PHE 456 -0.0003

PHE 456 ALA 457 0.0001

ALA 457 ILE 458 -0.0002

ILE 458 PHE 459 0.0001

PHE 459 ALA 460 -0.0102

ALA 460 ARG 461 -0.0003

ARG 461 ASP 462 -0.0002

ASP 462 MET 463 0.0000

MET 463 ASP 464 0.0004

ASP 464 MET 465 0.0003

MET 465 THR 466 0.0000

THR 466 LEU 467 0.0001

LEU 467 ASN 468 0.0001

ASN 468 ASN 469 0.0001

ASN 469 PRO 470 0.0000

PRO 470 CYS 471 -0.0004

CYS 471 TRP 472 0.0002

TRP 472 LYS 473 -0.0131

LYS 473 LYS 474 0.0001

LYS 474 LEU 475 -0.0000

LEU 475 GLN 476 -0.0003

GLN 476 ALA 477 0.0003

ALA 477 PRO 478 0.0001

PRO 478 TRP 479 0.0003

TRP 479 GLU 480 0.0002

GLU 480 SER 2 -0.0026

SER 2 GLN 3 -0.0001

GLN 3 GLN 4 0.0001

GLN 4 VAL 5 0.0001

VAL 5 ASP 6 -0.0001

ASP 6 LYS 7 -0.0001

LYS 7 ILE 8 -0.0001

ILE 8 LYS 9 0.0002

LYS 9 ALA 10 0.0001

ALA 10 SER 11 0.0004

SER 11 TYR 12 -0.0000

TYR 12 PRO 13 0.0001

PRO 13 LEU 14 -0.0001

LEU 14 PHE 15 -0.0156

PHE 15 LEU 16 0.0001

LEU 16 ASP 17 0.0002

ASP 17 GLN 18 0.0000

GLN 18 ASP 19 0.0004

ASP 19 TYR 20 -0.0002

TYR 20 LYS 21 -0.0001

LYS 21 ASP 22 -0.0002

ASP 22 MET 23 0.0001

MET 23 LEU 24 0.0001

LEU 24 ALA 25 0.0003

ALA 25 LYS 26 0.0002

LYS 26 LYS 27 0.0001

LYS 27 ARG 28 0.0081

ARG 28 ASP 29 0.0001

ASP 29 GLY 30 0.0001

GLY 30 PHE 31 0.0001

PHE 31 GLU 32 -0.0001

GLU 32 GLU 33 -0.0001

GLU 33 LYS 34 -0.0000

LYS 34 TYR 35 0.0004

TYR 35 PRO 36 -0.0004

PRO 36 GLN 37 -0.0003

GLN 37 ASP 38 0.0000

ASP 38 LYS 39 -0.0000

LYS 39 ILE 40 0.0000

ILE 40 ASP 41 -0.0075

ASP 41 GLU 42 0.0000

GLU 42 VAL 43 -0.0001

VAL 43 PHE 44 -0.0003

PHE 44 GLN 45 0.0001

GLN 45 GLN 45 -0.0000

GLN 45 TRP 46 -0.0001

TRP 46 THR 47 0.0000

THR 47 THR 48 -0.0000

THR 48 THR 49 -0.0001

THR 49 LYS 50 -0.0001

LYS 50 GLU 51 -0.0000

GLU 51 TYR 52 0.0006

TYR 52 GLN 53 -0.0001

GLN 53 GLU 54 -0.0077

GLU 54 LEU 55 -0.0001

LEU 55 ASN 56 -0.0000

ASN 56 PHE 57 -0.0005

PHE 57 GLN 58 0.0001

GLN 58 ARG 59 -0.0003

ARG 59 GLU 60 0.0004

GLU 60 ALA 61 0.0001

ALA 61 LEU 62 -0.0001

LEU 62 THR 63 -0.0002

THR 63 VAL 64 -0.0000

VAL 64 ASN 65 0.0005

ASN 65 PRO 66 -0.0003

PRO 66 ALA 67 0.0038

ALA 67 LYS 68 -0.0000

LYS 68 ALA 69 0.0001

ALA 69 CYS 70 0.0001

CYS 70 GLN 71 0.0001

GLN 71 PRO 72 -0.0002

PRO 72 LEU 73 -0.0001

LEU 73 GLY 74 0.0004

GLY 74 ALA 75 -0.0001

ALA 75 VAL 76 0.0002

VAL 76 LEU 77 -0.0002

LEU 77 CYS 78 -0.0001

CYS 78 ALA 79 0.0001

ALA 79 LEU 80 0.0065

LEU 80 GLY 81 0.0002

GLY 81 PHE 82 0.0001

PHE 82 GLU 83 -0.0001

GLU 83 LYS 84 -0.0002

LYS 84 THR 85 0.0000

THR 85 MET 86 -0.0002

MET 86 PRO 87 0.0004

PRO 87 TYR 88 0.0002

TYR 88 VAL 89 0.0002

VAL 89 HIS 90 -0.0005

HIS 90 GLY 91 0.0000

GLY 91 SER 92 -0.0001

SER 92 GLN 93 0.0092

GLN 93 GLY 94 -0.0002

GLY 94 CYS 95 -0.0001

CYS 95 VAL 96 0.0002

VAL 96 ALA 97 0.0002

ALA 97 TYR 98 0.0001

TYR 98 PHE 99 0.0001

PHE 99 ARG 100 0.0000

ARG 100 SER 101 -0.0000

SER 101 TYR 102 -0.0001

TYR 102 PHE 103 0.0001

PHE 103 ASN 104 -0.0003

ASN 104 ARG 105 -0.0001

ARG 105 HIS 106 -0.0083

HIS 106 PHE 107 -0.0001

PHE 107 ARG 108 0.0004

ARG 108 GLU 109 -0.0003

GLU 109 PRO 110 -0.0001

PRO 110 VAL 111 0.0001

VAL 111 SER 112 0.0001

SER 112 CYS 113 -0.0001

CYS 113 VAL 114 -0.0002

VAL 114 SER 115 0.0002

SER 115 ASP 116 0.0003

ASP 116 SER 117 -0.0004

SER 117 MET 118 -0.0002

MET 118 THR 119 0.0212

THR 119 GLU 120 0.0000

GLU 120 ASP 121 0.0003

ASP 121 ALA 122 -0.0001

ALA 122 ALA 123 0.0000

ALA 123 VAL 124 -0.0000

VAL 124 PHE 125 -0.0005

PHE 125 GLY 126 -0.0001

GLY 126 GLY 127 0.0000

GLY 127 GLN 128 -0.0000

GLN 128 GLN 129 0.0001

GLN 129 ASN 130 -0.0002

ASN 130 MET 131 -0.0003

MET 131 LYS 132 -0.0005

LYS 132 ASP 133 -0.0003

ASP 133 GLY 134 0.0003

GLY 134 LEU 135 0.0001

LEU 135 GLN 136 -0.0003

GLN 136 ASN 137 0.0004

ASN 137 CYS 138 0.0002

CYS 138 LYS 139 0.0001

LYS 139 ALA 140 0.0003

ALA 140 THR 141 0.0000

THR 141 TYR 142 0.0001

TYR 142 LYS 143 -0.0000

LYS 143 PRO 144 0.0000

PRO 144 ASP 145 -0.0051

ASP 145 MET 146 0.0001

MET 146 ILE 147 0.0001

ILE 147 ALA 148 -0.0001

ALA 148 VAL 149 -0.0002

VAL 149 SER 150 -0.0002

SER 150 THR 151 -0.0000

THR 151 THR 152 0.0003

THR 152 CYS 153 -0.0004

CYS 153 MET 154 0.0000

MET 154 ALA 155 -0.0001

ALA 155 GLU 156 -0.0001

GLU 156 VAL 157 0.0000

VAL 157 ILE 158 0.0094

ILE 158 GLY 159 -0.0000

GLY 159 ASP 160 0.0002

ASP 160 ASP 161 0.0002

ASP 161 LEU 162 -0.0003

LEU 162 ASN 163 -0.0004

ASN 163 ALA 164 0.0003

ALA 164 PHE 165 -0.0002

PHE 165 ILE 166 -0.0002

ILE 166 ASN 167 0.0002

ASN 167 ASN 168 0.0002

ASN 168 SER 169 0.0000

SER 169 LYS 170 0.0000

LYS 170 LYS 171 -0.0225

LYS 171 GLU 172 -0.0004

GLU 172 GLY 173 -0.0003

GLY 173 PHE 174 -0.0001

PHE 174 ILE 175 -0.0001

ILE 175 PRO 176 0.0004

PRO 176 ASP 177 -0.0003

ASP 177 GLU 178 -0.0001

GLU 178 PHE 179 -0.0000

PHE 179 PRO 180 -0.0000

PRO 180 VAL 181 0.0003

VAL 181 PRO 182 0.0000

PRO 182 PHE 183 -0.0004

PHE 183 ALA 184 -0.0141

ALA 184 HIS 185 0.0000

HIS 185 THR 186 -0.0002

THR 186 PRO 187 -0.0001

PRO 187 SER 188 0.0002

SER 188 PHE 189 0.0001

PHE 189 VAL 190 0.0001

VAL 190 GLY 191 -0.0001

GLY 191 SER 192 0.0004

SER 192 HIS 193 -0.0002

HIS 193 VAL 194 -0.0000

VAL 194 THR 195 0.0001

THR 195 GLY 196 0.0003

GLY 196 TRP 197 0.0182

TRP 197 ASP 198 0.0001

ASP 198 ASN 199 0.0000

ASN 199 MET 200 0.0001

MET 200 PHE 201 0.0002

PHE 201 GLU 202 -0.0002

GLU 202 GLY 203 -0.0000

GLY 203 ILE 204 -0.0002

ILE 204 ALA 205 0.0001

ALA 205 ARG 206 -0.0002

ARG 206 TYR 207 0.0001

TYR 207 PHE 208 -0.0003

PHE 208 THR 209 0.0001

THR 209 LEU 210 -0.0078

LEU 210 LYS 211 -0.0005

LYS 211 SER 212 -0.0002

SER 212 MET 213 0.0001

MET 213 ASP 214 -0.0001

ASP 214 ASP 215 -0.0004

ASP 215 LYS 216 0.0000

LYS 216 VAL 217 0.0000

VAL 217 VAL 218 -0.0000

VAL 218 GLY 219 0.0000

GLY 219 SER 220 0.0001

SER 220 ASN 221 0.0001

ASN 221 LYS 222 -0.0003

LYS 222 LYS 223 -0.0120

LYS 223 ILE 224 0.0001

ILE 224 ASN 225 -0.0002

ASN 225 ILE 226 -0.0003

ILE 226 VAL 227 -0.0000

VAL 227 PRO 228 -0.0001

PRO 228 GLY 229 -0.0001

GLY 229 PHE 230 0.0001

PHE 230 GLU 231 -0.0000

GLU 231 THR 232 -0.0003

THR 232 TYR 233 0.0003

TYR 233 LEU 234 0.0004

LEU 234 GLY 235 0.0001

GLY 235 ASN 236 -0.0174

ASN 236 PHE 237 -0.0003

PHE 237 ARG 238 0.0003

ARG 238 VAL 239 0.0001

VAL 239 ILE 240 0.0002

ILE 240 LYS 241 0.0001

LYS 241 ARG 242 0.0002

ARG 242 MET 243 -0.0001

MET 243 LEU 244 -0.0003

LEU 244 SER 245 -0.0002

SER 245 GLU 246 0.0004

GLU 246 MET 247 -0.0002

MET 247 GLY 248 0.0001

GLY 248 VAL 249 0.0527

VAL 249 GLY 250 -0.0001

GLY 250 TYR 251 0.0000

TYR 251 SER 252 0.0002

SER 252 LEU 253 0.0003

LEU 253 LEU 254 -0.0003

LEU 254 SER 255 -0.0002

SER 255 ASP 256 0.0002

ASP 256 PRO 257 0.0005

PRO 257 GLU 258 -0.0001

GLU 258 GLU 259 0.0002

GLU 259 VAL 260 -0.0001

VAL 260 LEU 261 -0.0001

LEU 261 ASP 262 0.0311

ASP 262 THR 263 -0.0002

THR 263 PRO 264 0.0003

PRO 264 ALA 265 0.0003

ALA 265 ASP 266 -0.0001

ASP 266 GLY 267 -0.0004

GLY 267 GLN 268 0.0004

GLN 268 PHE 269 0.0002

PHE 269 ARG 270 0.0001

ARG 270 MET 271 0.0000

MET 271 TYR 272 -0.0002

TYR 272 ALA 273 0.0003

ALA 273 GLY 274 -0.0001

GLY 274 GLY 275 0.0223

GLY 275 THR 276 -0.0000

THR 276 THR 277 -0.0002

THR 277 GLN 278 -0.0004

GLN 278 GLU 279 -0.0000

GLU 279 GLU 280 0.0001

GLU 280 MET 281 0.0001

MET 281 LYS 282 0.0002

LYS 282 ASP 283 0.0000

ASP 283 ALA 284 0.0000

ALA 284 PRO 285 0.0000

PRO 285 ASN 286 -0.0001

ASN 286 ALA 287 0.0002

ALA 287 LEU 288 0.0122

LEU 288 ASN 289 0.0000

ASN 289 THR 290 -0.0003

THR 290 VAL 291 0.0002

VAL 291 LEU 292 0.0002

LEU 292 LEU 293 0.0001

LEU 293 GLN 294 -0.0003

GLN 294 PRO 295 -0.0001

PRO 295 TRP 296 0.0001

TRP 296 HIS 297 0.0003

HIS 297 LEU 298 0.0003

LEU 298 GLU 299 0.0000

GLU 299 LYS 300 -0.0001

LYS 300 THR 301 -0.0218

THR 301 LYS 302 -0.0001

LYS 302 LYS 303 0.0000

LYS 303 PHE 304 -0.0004

PHE 304 VAL 305 -0.0001

VAL 305 GLU 306 -0.0001

GLU 306 GLY 307 -0.0000

GLY 307 THR 308 -0.0000

THR 308 TRP 309 -0.0003

TRP 309 LYS 310 -0.0001

LYS 310 HIS 311 0.0003

HIS 311 GLU 312 -0.0004

GLU 312 VAL 313 0.0000

VAL 313 PRO 314 0.0354

PRO 314 LYS 315 -0.0000

LYS 315 LEU 316 0.0002

LEU 316 ASN 317 -0.0001

ASN 317 ILE 318 0.0001

ILE 318 PRO 319 0.0002

PRO 319 MET 320 -0.0002

MET 320 GLY 321 -0.0003

GLY 321 LEU 322 0.0001

LEU 322 ASP 323 -0.0001

ASP 323 TRP 324 0.0003

TRP 324 THR 325 0.0002

THR 325 ASP 326 0.0002

ASP 326 GLU 327 -0.0124

GLU 327 PHE 328 -0.0002

PHE 328 LEU 329 0.0000

LEU 329 MET 330 -0.0004

MET 330 LYS 331 0.0002

LYS 331 VAL 332 0.0000

VAL 332 SER 333 0.0004

SER 333 GLU 334 -0.0000

GLU 334 ILE 335 0.0001

ILE 335 SER 336 0.0001

SER 336 GLY 337 -0.0002

GLY 337 GLN 338 0.0001

GLN 338 PRO 339 -0.0001

PRO 339 ILE 340 0.0433

ILE 340 PRO 341 0.0001

PRO 341 ALA 342 0.0005

ALA 342 SER 343 -0.0001

SER 343 LEU 344 0.0003

LEU 344 THR 345 0.0002

THR 345 LYS 346 0.0001

LYS 346 GLU 347 -0.0002

GLU 347 ARG 348 0.0000

ARG 348 GLY 349 0.0001

GLY 349 ARG 350 0.0000

ARG 350 LEU 351 0.0001

LEU 351 VAL 352 0.0004

VAL 352 ASP 353 0.0102

ASP 353 MET 354 0.0002

MET 354 MET 355 0.0001

MET 355 THR 356 -0.0000

THR 356 ASP 357 -0.0002

ASP 357 SER 358 -0.0002

SER 358 HIS 359 -0.0000

HIS 359 THR 360 0.0001

THR 360 TRP 361 0.0002

TRP 361 LEU 362 -0.0000

LEU 362 HIS 363 -0.0001

HIS 363 GLY 364 0.0001

GLY 364 LYS 365 0.0001

LYS 365 ARG 366 -0.0476

ARG 366 PHE 367 0.0004

PHE 367 ALA 368 -0.0002

ALA 368 LEU 369 0.0001

LEU 369 TRP 370 0.0002

TRP 370 GLY 371 0.0000

GLY 371 ASP 372 0.0000

ASP 372 PRO 373 0.0003

PRO 373 ASP 374 0.0001

ASP 374 PHE 375 0.0002

PHE 375 VAL 376 -0.0001

VAL 376 MET 377 -0.0000

MET 377 GLY 378 -0.0001

GLY 378 LEU 379 0.0025

LEU 379 VAL 380 0.0001

VAL 380 LYS 381 -0.0000

LYS 381 PHE 382 0.0003

PHE 382 LEU 383 -0.0002

LEU 383 LEU 384 0.0001

LEU 384 GLU 385 0.0005

GLU 385 LEU 386 0.0001

LEU 386 GLY 387 0.0001

GLY 387 CYS 388 0.0000

CYS 388 GLU 389 0.0000

GLU 389 PRO 390 -0.0001

PRO 390 VAL 391 0.0002

VAL 391 HIS 392 -0.0064

HIS 392 ILE 393 0.0002

ILE 393 LEU 394 -0.0002

LEU 394 CYS 395 0.0001

CYS 395 HIS 396 -0.0001

HIS 396 ASN 397 -0.0002

ASN 397 GLY 398 -0.0001

GLY 398 ASN 399 0.0004

ASN 399 LYS 400 -0.0004

LYS 400 ARG 401 -0.0003

ARG 401 TRP 402 -0.0001

TRP 402 LYS 403 -0.0006

LYS 403 LYS 404 -0.0000

LYS 404 ALA 405 0.0147

ALA 405 VAL 406 -0.0001

VAL 406 ASP 407 0.0001

ASP 407 ALA 408 0.0001

ALA 408 ILE 409 -0.0000

ILE 409 LEU 410 0.0002

LEU 410 ALA 411 -0.0005

ALA 411 ALA 412 0.0001

ALA 412 SER 413 0.0001

SER 413 PRO 414 0.0000

PRO 414 TYR 415 -0.0004

TYR 415 GLY 416 0.0001

GLY 416 LYS 417 -0.0001

LYS 417 ASN 418 0.0017

ASN 418 ALA 419 -0.0004

ALA 419 THR 420 -0.0001

THR 420 VAL 421 0.0004

VAL 421 TYR 422 -0.0000

TYR 422 ILE 423 -0.0004

ILE 423 GLY 424 0.0003

GLY 424 LYS 425 0.0002

LYS 425 ASP 426 0.0002

ASP 426 LEU 427 0.0000

LEU 427 TRP 428 -0.0002

TRP 428 HIS 429 -0.0002

HIS 429 LEU 430 -0.0000

LEU 430 ARG 431 0.0027

ARG 431 SER 432 0.0000

SER 432 LEU 433 0.0002

LEU 433 VAL 434 0.0004

VAL 434 PHE 435 -0.0003

PHE 435 THR 436 -0.0002

THR 436 ASP 437 -0.0002

ASP 437 LYS 438 0.0000

LYS 438 PRO 439 -0.0000

PRO 439 ASP 440 0.0000

ASP 440 PHE 441 0.0001

PHE 441 MET 442 -0.0000

MET 442 ILE 443 -0.0002

ILE 443 GLY 444 -0.0112

GLY 444 ASN 445 0.0001

ASN 445 SER 446 0.0001

SER 446 TYR 447 0.0004

TYR 447 GLY 448 0.0001

GLY 448 LYS 449 -0.0001

LYS 449 PHE 450 -0.0002

PHE 450 ILE 451 0.0002

ILE 451 GLN 452 -0.0001

GLN 452 ARG 453 0.0000

ARG 453 ASP 454 0.0000

ASP 454 THR 455 -0.0005

THR 455 LEU 456 0.0000

LEU 456 HIS 457 0.0089

HIS 457 LYS 458 0.0002

LYS 458 GLY 459 0.0004

GLY 459 LYS 460 -0.0001

LYS 460 GLU 461 -0.0002

GLU 461 PHE 462 0.0002

PHE 462 GLU 463 0.0003

GLU 463 VAL 464 0.0000

VAL 464 PRO 465 -0.0002

PRO 465 LEU 466 -0.0001

LEU 466 ILE 467 0.0000

ILE 467 ARG 468 -0.0002

ARG 468 ILE 469 0.0000

ILE 469 GLY 470 -0.0152

GLY 470 PHE 471 0.0003

PHE 471 PRO 472 -0.0005

PRO 472 ILE 473 0.0001

ILE 473 PHE 474 -0.0004

PHE 474 ASP 475 0.0001

ASP 475 ARG 476 -0.0001

ARG 476 HIS 477 -0.0000

HIS 477 HIS 478 0.0000

HIS 478 LEU 479 -0.0002

LEU 479 HIS 480 -0.0003

HIS 480 ARG 481 0.0002

ARG 481 SER 482 0.0000

SER 482 THR 483 -0.0309

THR 483 THR 484 0.0001

THR 484 LEU 485 -0.0002

LEU 485 GLY 486 0.0002

GLY 486 TYR 487 0.0000

TYR 487 GLU 488 -0.0002

GLU 488 GLY 489 0.0001

GLY 489 ALA 490 -0.0004

ALA 490 MET 491 -0.0003

MET 491 GLN 492 0.0001

GLN 492 ILE 493 -0.0003

ILE 493 LEU 494 -0.0002

LEU 494 THR 495 0.0000

THR 495 THR 496 -0.0084

THR 496 LEU 497 -0.0001

LEU 497 VAL 498 0.0003

VAL 498 ASN 499 0.0003

ASN 499 SER 500 -0.0001

SER 500 ILE 501 -0.0001

ILE 501 LEU 502 -0.0002

LEU 502 GLU 503 0.0001

GLU 503 ARG 504 0.0001

ARG 504 LEU 505 -0.0003

LEU 505 ASP 506 0.0000

ASP 506 GLU 507 0.0004

GLU 507 GLU 508 -0.0001

GLU 508 THR 509 -0.0872

THR 509 ARG 510 0.0002

ARG 510 GLY 511 0.0000

GLY 511 MET 512 0.0003

MET 512 GLN 513 -0.0001

GLN 513 ALA 514 -0.0004

ALA 514 THR 515 0.0002

THR 515 ASP 516 -0.0000

ASP 516 TYR 517 -0.0001

TYR 517 ASN 518 0.0001

ASN 518 HIS 519 0.0000

HIS 519 ASP 520 0.0000

ASP 520 LEU 521 0.0002

LEU 521 VAL 522 0.0070

VAL 522 ARG 523 -0.0002

ARG 523 SER 5 -0.0006

SER 5 ARG 6 0.0003

ARG 6 GLU 7 -0.0000

GLU 7 GLU 8 -0.0001

GLU 8 VAL 9 0.0002

VAL 9 GLU 10 -0.0003

GLU 10 SER 11 0.0001

SER 11 LEU 12 -0.0002

LEU 12 ILE 13 0.0004

ILE 13 GLN 14 0.0002

GLN 14 GLU 15 -0.0003

GLU 15 VAL 16 0.0000

VAL 16 LEU 17 -0.0000

LEU 17 GLU 18 0.0018

GLU 18 VAL 19 0.0000

VAL 19 TYR 20 0.0003

TYR 20 PRO 21 0.0002

PRO 21 GLU 22 -0.0001

GLU 22 LYS 23 0.0001

LYS 23 ALA 24 0.0000

ALA 24 ARG 25 -0.0002

ARG 25 LYS 26 0.0001

LYS 26 ASP 27 0.0005

ASP 27 ARG 28 0.0001

ARG 28 ASN 29 0.0000

ASN 29 LYS 30 -0.0004

LYS 30 HIS 31 -0.0002

HIS 31 LEU 32 -0.0000

LEU 32 ALA 33 -0.0001

ALA 33 VAL 34 -0.0002

VAL 34 ASN 35 -0.0001

ASN 35 ASP 36 -0.0001

ASP 36 PRO 37 -0.0001

PRO 37 ALA 38 0.0003

ALA 38 VAL 39 -0.0002

VAL 39 THR 40 0.0000

THR 40 GLN 41 0.0004

GLN 41 SER 42 0.0001

SER 42 LYS 43 -0.0001

LYS 43 LYS 44 0.0001

LYS 44 CYS 45 0.0001

CYS 45 ILE 46 0.0000

ILE 46 ILE 47 0.0003

ILE 47 SER 48 0.0002

SER 48 ASN 49 0.0002

ASN 49 LYS 50 -0.0002

LYS 50 LYS 51 -0.0002

LYS 51 SER 52 -0.0001

SER 52 GLN 53 -0.0002

GLN 53 PRO 54 -0.0000

PRO 54 GLY 55 -0.0001

GLY 55 LEU 56 -0.0001

LEU 56 MET 57 0.0003

MET 57 THR 58 -0.0002

THR 58 ILE 59 0.0001

ILE 59 ARG 60 -0.0002

ARG 60 GLY 61 -0.0004

GLY 61 CYS 62 -0.0001

CYS 62 ALA 63 0.0000

ALA 63 TYR 64 0.0000

TYR 64 ALA 65 0.0000

ALA 65 GLY 66 0.0002

GLY 66 SER 67 -0.0004

SER 67 LYS 68 0.0003

LYS 68 GLY 69 -0.0001

GLY 69 VAL 70 0.0045

VAL 70 VAL 71 -0.0003

VAL 71 TRP 72 0.0004

TRP 72 GLY 73 0.0001

GLY 73 PRO 74 -0.0002

PRO 74 ILE 75 0.0000

ILE 75 LYS 76 0.0002

LYS 76 ASP 77 0.0000

ASP 77 MET 78 0.0002

MET 78 ILE 79 -0.0001

ILE 79 HIS 80 0.0001

HIS 80 ILE 81 0.0002

ILE 81 SER 82 -0.0001

SER 82 HIS 83 0.0069

HIS 83 GLY 84 0.0001

GLY 84 PRO 85 -0.0002

PRO 85 VAL 86 0.0001

VAL 86 GLY 87 -0.0001

GLY 87 CYS 88 -0.0002

CYS 88 GLY 89 0.0004

GLY 89 GLN 90 -0.0002

GLN 90 TYR 91 0.0001

TYR 91 SER 92 -0.0001

SER 92 ARG 93 0.0002

ARG 93 ALA 94 -0.0001

ALA 94 GLY 95 0.0002

GLY 95 ARG 96 0.0062

ARG 96 ARG 97 0.0001

ARG 97 ASN 98 0.0001

ASN 98 TYR 99 -0.0002

TYR 99 TYR 100 -0.0004

TYR 100 ILE 101 -0.0001

ILE 101 GLY 102 0.0004

GLY 102 THR 103 0.0001

THR 103 THR 104 0.0003

THR 104 GLY 105 0.0001

GLY 105 VAL 106 -0.0002

VAL 106 ASN 107 0.0005

ASN 107 ALA 108 0.0001

ALA 108 PHE 109 -0.0036

PHE 109 VAL 110 -0.0002

VAL 110 THR 111 -0.0001

THR 111 MET 112 -0.0004

MET 112 ASN 113 0.0000

ASN 113 PHE 114 0.0003

PHE 114 THR 115 -0.0002

THR 115 SER 116 -0.0002

SER 116 ASP 117 -0.0002

ASP 117 PHE 118 -0.0001

PHE 118 GLN 119 0.0002

GLN 119 GLU 120 -0.0000

GLU 120 LYS 121 -0.0001

LYS 121 ASP 122 0.0069

ASP 122 ILE 123 -0.0004

ILE 123 VAL 124 -0.0001

VAL 124 PHE 125 0.0002

PHE 125 GLY 126 -0.0000

GLY 126 GLY 127 0.0001

GLY 127 ASP 128 0.0000

ASP 128 LYS 129 -0.0001

LYS 129 LYS 130 -0.0003

LYS 130 LEU 131 0.0004

LEU 131 ALA 132 -0.0000

ALA 132 LYS 133 0.0001

LYS 133 LEU 134 0.0002

LEU 134 ILE 135 0.0018

ILE 135 ASP 136 0.0003

ASP 136 GLU 137 0.0000

GLU 137 VAL 138 -0.0000

VAL 138 GLU 139 0.0004

GLU 139 THR 140 -0.0000

THR 140 LEU 141 -0.0002

LEU 141 PHE 142 -0.0000

PHE 142 PRO 143 -0.0001

PRO 143 LEU 144 -0.0000

LEU 144 ASN 145 0.0003

ASN 145 LYS 146 0.0002

LYS 146 GLY 147 -0.0003

GLY 147 ILE 148 -0.0019

ILE 148 SER 149 -0.0000

SER 149 VAL 150 -0.0000

VAL 150 GLN 151 -0.0003

GLN 151 SER 152 -0.0002

SER 152 GLU 153 0.0003

GLU 153 CYS 154 0.0002

CYS 154 PRO 155 -0.0000

PRO 155 ILE 156 0.0001

ILE 156 GLY 157 -0.0003

GLY 157 LEU 158 0.0001

LEU 158 ILE 159 0.0003

ILE 159 GLY 160 0.0004

GLY 160 ASP 161 0.0026

ASP 161 ASP 162 0.0003

ASP 162 ILE 163 0.0001

ILE 163 GLU 164 -0.0000

GLU 164 SER 165 -0.0001

SER 165 VAL 166 -0.0002

VAL 166 SER 167 0.0003

SER 167 LYS 168 -0.0001

LYS 168 VAL 169 0.0001

VAL 169 LYS 170 0.0003

LYS 170 GLY 171 -0.0001

GLY 171 ALA 172 -0.0003

ALA 172 GLU 173 0.0002

GLU 173 LEU 174 -0.0007

LEU 174 SER 175 -0.0001

SER 175 LYS 176 0.0003

LYS 176 THR 177 -0.0003

THR 177 ILE 178 -0.0000

ILE 178 VAL 179 0.0001

VAL 179 PRO 180 -0.0000

PRO 180 VAL 181 -0.0002

VAL 181 ARG 182 0.0000

ARG 182 CYS 183 -0.0002

CYS 183 GLU 184 0.0000

GLU 184 GLY 185 -0.0001

GLY 185 PHE 186 -0.0005

PHE 186 ARG 187 0.0066

ARG 187 GLY 188 -0.0001

GLY 188 VAL 189 -0.0003

VAL 189 SER 190 0.0004

SER 190 GLN 191 -0.0003

GLN 191 SER 192 -0.0002

SER 192 LEU 193 -0.0002

LEU 193 GLY 194 -0.0000

GLY 194 HIS 195 -0.0001

HIS 195 HIS 196 -0.0000

HIS 196 ILE 197 0.0001

ILE 197 ALA 198 -0.0000

ALA 198 ASN 199 -0.0000

ASN 199 ASP 200 -0.0044

ASP 200 ALA 201 0.0005

ALA 201 VAL 202 -0.0000

VAL 202 ARG 203 0.0003

ARG 203 ASP 204 -0.0000

ASP 204 TRP 205 -0.0001

TRP 205 VAL 206 0.0001

VAL 206 LEU 207 0.0001

LEU 207 GLY 208 -0.0004

GLY 208 LYS 209 -0.0002

LYS 209 ARG 210 0.0000

ARG 210 ASP 211 0.0000

ASP 211 GLU 212 0.0003

GLU 212 ASP 213 0.0049

ASP 213 THR 214 -0.0000

THR 214 THR 215 -0.0001

THR 215 PHE 216 0.0001

PHE 216 ALA 217 -0.0004

ALA 217 SER 218 0.0003

SER 218 THR 219 -0.0001

THR 219 PRO 220 0.0000

PRO 220 TYR 221 -0.0001

TYR 221 ASP 222 -0.0003

ASP 222 VAL 223 0.0002

VAL 223 ALA 224 -0.0005

ALA 224 ILE 225 0.0002

ILE 225 ILE 226 0.0048

ILE 226 GLY 227 0.0000

GLY 227 ASP 228 -0.0001

ASP 228 TYR 229 0.0002

TYR 229 ASN 230 -0.0002

ASN 230 ILE 231 -0.0002

ILE 231 GLY 232 0.0001

GLY 232 GLY 233 -0.0001

GLY 233 ASP 234 -0.0002

ASP 234 ALA 235 -0.0005

ALA 235 TRP 236 0.0002

TRP 236 SER 237 -0.0001

SER 237 SER 238 -0.0002

SER 238 ARG 239 -0.0009

ARG 239 ILE 240 -0.0003

ILE 240 LEU 241 0.0001

LEU 241 LEU 242 -0.0000

LEU 242 GLU 243 0.0003

GLU 243 GLU 244 0.0002

GLU 244 MET 245 0.0003

MET 245 GLY 246 0.0001

GLY 246 LEU 247 0.0001

LEU 247 ARG 248 0.0000

ARG 248 CYS 249 -0.0002

CYS 249 VAL 250 -0.0001

VAL 250 ALA 251 0.0002

ALA 251 GLN 252 0.0004

GLN 252 TRP 253 -0.0002

TRP 253 SER 254 -0.0000

SER 254 GLY 255 -0.0001

GLY 255 ASP 256 -0.0002

ASP 256 GLY 257 -0.0003

GLY 257 SER 258 0.0000

SER 258 ILE 259 -0.0000

ILE 259 SER 260 0.0003

SER 260 GLU 261 -0.0002

GLU 261 ILE 262 0.0001

ILE 262 GLU 263 -0.0001

GLU 263 LEU 264 -0.0003

LEU 264 THR 265 0.0001

THR 265 PRO 266 0.0004

PRO 266 LYS 267 -0.0000

LYS 267 VAL 268 0.0003

VAL 268 LYS 269 -0.0002

LYS 269 LEU 270 0.0001

LEU 270 ASN 271 0.0004

ASN 271 LEU 272 0.0001

LEU 272 VAL 273 0.0001

VAL 273 HIS 274 -0.0002

HIS 274 CYS 275 -0.0001

CYS 275 TYR 276 0.0000

TYR 276 ARG 277 0.0000

ARG 277 SER 278 -0.0006

SER 278 MET 279 -0.0002

MET 279 ASN 280 -0.0001

ASN 280 TYR 281 -0.0003

TYR 281 ILE 282 -0.0001

ILE 282 SER 283 -0.0001

SER 283 ARG 284 -0.0002

ARG 284 HIS 285 0.0001

HIS 285 MET 286 0.0001

MET 286 GLU 287 0.0004

GLU 287 GLU 288 0.0001

GLU 288 LYS 289 -0.0001

LYS 289 TYR 290 -0.0001

TYR 290 GLY 291 -0.0004

GLY 291 ILE 292 -0.0003

ILE 292 PRO 293 -0.0003

PRO 293 TRP 294 -0.0001

TRP 294 MET 295 0.0003

MET 295 GLU 296 0.0000

GLU 296 TYR 297 0.0001

TYR 297 ASN 298 -0.0001

ASN 298 PHE 299 0.0002

PHE 299 PHE 300 -0.0005

PHE 300 GLY 301 0.0000

GLY 301 PRO 302 -0.0002

PRO 302 THR 303 -0.0000

THR 303 LYS 304 -0.0003

LYS 304 THR 305 0.0000

THR 305 ILE 306 0.0005

ILE 306 GLU 307 -0.0002

GLU 307 SER 308 -0.0001

SER 308 LEU 309 -0.0001

LEU 309 ARG 310 0.0002

ARG 310 ALA 311 0.0002

ALA 311 ILE 312 0.0000

ILE 312 ALA 313 -0.0003

ALA 313 ALA 314 0.0002

ALA 314 LYS 315 0.0002

LYS 315 PHE 316 -0.0000

PHE 316 ASP 317 0.0016

ASP 317 GLU 318 0.0000

GLU 318 SER 319 -0.0002

SER 319 ILE 320 0.0004

ILE 320 GLN 321 0.0000

GLN 321 LYS 322 -0.0004

LYS 322 LYS 323 -0.0001

LYS 323 CYS 324 0.0000

CYS 324 GLU 325 0.0002

GLU 325 GLU 326 0.0002

GLU 326 VAL 327 -0.0001

VAL 327 ILE 328 -0.0004

ILE 328 ALA 329 0.0001

ALA 329 LYS 330 -0.0017

LYS 330 TYR 331 0.0001

TYR 331 LYS 332 -0.0001

LYS 332 PRO 333 0.0001

PRO 333 GLU 334 0.0002

GLU 334 TRP 335 -0.0004

TRP 335 GLU 336 -0.0001

GLU 336 ALA 337 0.0003

ALA 337 VAL 338 0.0000

VAL 338 VAL 339 -0.0001

VAL 339 ALA 340 -0.0003

ALA 340 LYS 341 0.0001

LYS 341 TYR 342 0.0001

TYR 342 ARG 343 0.0051

ARG 343 PRO 344 -0.0006

PRO 344 ARG 345 -0.0000

ARG 345 LEU 346 0.0001

LEU 346 GLU 347 -0.0002

GLU 347 GLY 348 0.0004

GLY 348 LYS 349 0.0000

LYS 349 ARG 350 0.0000

ARG 350 VAL 351 0.0000

VAL 351 MET 352 -0.0001

MET 352 LEU 353 0.0002

LEU 353 TYR 354 -0.0004

TYR 354 ILE 355 0.0001

ILE 355 GLY 356 0.0056

GLY 356 GLY 357 0.0001

GLY 357 LEU 358 -0.0000

LEU 358 ARG 359 0.0005

ARG 359 PRO 360 0.0000

PRO 360 ARG 361 -0.0001

ARG 361 HIS 362 -0.0003

HIS 362 VAL 363 0.0002

VAL 363 ILE 364 0.0002

ILE 364 GLY 365 -0.0002

GLY 365 ALA 366 0.0004

ALA 366 TYR 367 -0.0000

TYR 367 GLU 368 0.0002

GLU 368 ASP 369 0.0007

ASP 369 LEU 370 0.0001

LEU 370 GLY 371 0.0005

GLY 371 MET 372 0.0001

MET 372 GLU 373 0.0002

GLU 373 VAL 374 0.0001

VAL 374 VAL 375 -0.0002

VAL 375 GLY 376 0.0001

GLY 376 THR 377 0.0002

THR 377 GLY 378 -0.0001

GLY 378 TYR 379 0.0000

TYR 379 GLU 380 0.0001

GLU 380 PHE 381 0.0001

PHE 381 ALA 382 0.0001

ALA 382 HIS 383 -0.0003

HIS 383 ASN 384 -0.0002

ASN 384 ASP 385 0.0003

ASP 385 ASP 386 0.0002

ASP 386 TYR 387 0.0006

TYR 387 ASP 388 0.0001

ASP 388 ARG 389 -0.0000

ARG 389 THR 390 0.0002

THR 390 MET 391 0.0000

MET 391 LYS 392 -0.0001

LYS 392 GLU 393 -0.0001

GLU 393 MET 394 0.0001

MET 394 GLY 395 -0.0000

GLY 395 ASP 396 -0.0000

ASP 396 SER 397 -0.0003

SER 397 THR 398 0.0000

THR 398 LEU 399 -0.0004

LEU 399 LEU 400 0.0006

LEU 400 TYR 401 0.0002

TYR 401 ASP 402 -0.0001

ASP 402 ASP 403 -0.0000

ASP 403 VAL 404 -0.0000

VAL 404 THR 405 0.0002

THR 405 GLY 406 -0.0003

GLY 406 TYR 407 -0.0001

TYR 407 GLU 408 -0.0059

GLU 408 PHE 409 0.0001

PHE 409 GLU 410 -0.0003

GLU 410 GLU 411 0.0002

GLU 411 PHE 412 -0.0001

PHE 412 VAL 413 0.0003

VAL 413 LYS 414 -0.0001

LYS 414 ARG 415 0.0001

ARG 415 ILE 416 0.0005

ILE 416 LYS 417 -0.0002

LYS 417 PRO 418 -0.0000

PRO 418 ASP 419 0.0000

ASP 419 LEU 420 0.0003

LEU 420 ILE 421 -0.0060

ILE 421 GLY 422 -0.0002

GLY 422 SER 423 -0.0003

SER 423 GLY 424 0.0001

GLY 424 ILE 425 -0.0000

ILE 425 LYS 426 0.0000

LYS 426 GLU 427 -0.0000

GLU 427 LYS 428 -0.0001

LYS 428 PHE 429 0.0002

PHE 429 ILE 430 0.0002

ILE 430 PHE 431 0.0002

PHE 431 GLN 432 -0.0003

GLN 432 LYS 433 -0.0003

LYS 433 MET 434 -0.0013

MET 434 GLY 435 0.0001

GLY 435 ILE 436 0.0004

ILE 436 PRO 437 -0.0002

PRO 437 PHE 438 -0.0003

PHE 438 ARG 439 0.0001

ARG 439 GLU 440 -0.0003

GLU 440 MET 441 0.0002

MET 441 HIS 442 0.0004

HIS 442 SER 443 -0.0000

SER 443 TRP 444 -0.0003

TRP 444 ASP 445 0.0003

ASP 445 TYR 446 -0.0001

TYR 446 SER 447 -0.0022

SER 447 GLY 448 -0.0001

GLY 448 PRO 449 0.0001

PRO 449 TYR 450 0.0002

TYR 450 HIS 451 -0.0001

HIS 451 GLY 452 -0.0001

GLY 452 PHE 453 -0.0002

PHE 453 ASP 454 -0.0002

ASP 454 GLY 455 0.0001

GLY 455 PHE 456 -0.0002

PHE 456 ALA 457 -0.0002

ALA 457 ILE 458 -0.0003

ILE 458 PHE 459 -0.0003

PHE 459 ALA 460 -0.0065

ALA 460 ARG 461 0.0002

ARG 461 ASP 462 0.0002

ASP 462 MET 463 0.0001

MET 463 ASP 464 -0.0000

ASP 464 MET 465 0.0004

MET 465 THR 466 -0.0001

THR 466 LEU 467 0.0002

LEU 467 ASN 468 0.0003

ASN 468 ASN 469 0.0003

ASN 469 PRO 470 -0.0003

PRO 470 CYS 471 -0.0001

CYS 471 TRP 472 0.0001

TRP 472 LYS 473 0.0021

LYS 473 LYS 474 -0.0003

LYS 474 LEU 475 -0.0000

LEU 475 GLN 476 -0.0005

GLN 476 ALA 477 0.0001

ALA 477 PRO 478 -0.0003

PRO 478 TRP 479 -0.0000

TRP 479 GLU 480 0.0002

GLU 480 SER 2 -0.0016

SER 2 GLN 3 0.0002

GLN 3 GLN 4 -0.0002

GLN 4 VAL 5 -0.0002

VAL 5 ASP 6 -0.0000

ASP 6 LYS 7 0.0002

LYS 7 ILE 8 -0.0001

ILE 8 LYS 9 0.0000

LYS 9 ALA 10 -0.0002

ALA 10 SER 11 -0.0000

SER 11 TYR 12 0.0000

TYR 12 PRO 13 -0.0005

PRO 13 LEU 14 0.0001

LEU 14 PHE 15 -0.0099

PHE 15 LEU 16 0.0000

LEU 16 ASP 17 -0.0002

ASP 17 GLN 18 -0.0003

GLN 18 ASP 19 0.0000

ASP 19 TYR 20 0.0002

TYR 20 LYS 21 -0.0000

LYS 21 ASP 22 0.0000

ASP 22 MET 23 0.0000

MET 23 LEU 24 -0.0001

LEU 24 ALA 25 0.0004

ALA 25 LYS 26 0.0000

LYS 26 LYS 27 -0.0004

LYS 27 ARG 28 0.0046

ARG 28 ASP 29 0.0002

ASP 29 GLY 30 0.0001

GLY 30 PHE 31 0.0001

PHE 31 GLU 32 0.0003

GLU 32 GLU 33 -0.0003

GLU 33 LYS 34 -0.0002

LYS 34 TYR 35 0.0001

TYR 35 PRO 36 0.0002

PRO 36 GLN 37 0.0000

GLN 37 ASP 38 0.0001

ASP 38 LYS 39 -0.0003

LYS 39 ILE 40 0.0002

ILE 40 ASP 41 -0.0098

ASP 41 GLU 42 0.0001

GLU 42 VAL 43 -0.0001

VAL 43 PHE 44 -0.0003

PHE 44 GLN 45 0.0001

GLN 45 TRP 46 -0.0005

TRP 46 THR 47 -0.0001

THR 47 THR 48 0.0001

THR 48 THR 49 0.0000

THR 49 LYS 50 0.0001

LYS 50 GLU 51 -0.0002

GLU 51 TYR 52 -0.0001

TYR 52 GLN 53 -0.0002

GLN 53 GLU 54 -0.0054

GLU 54 LEU 55 -0.0002

LEU 55 ASN 56 0.0001

ASN 56 PHE 57 0.0002

PHE 57 GLN 58 0.0003

GLN 58 ARG 59 0.0002

ARG 59 GLU 60 0.0002

GLU 60 ALA 61 0.0001

ALA 61 LEU 62 0.0003

LEU 62 THR 63 -0.0002

THR 63 VAL 64 0.0001

VAL 64 ASN 65 -0.0001

ASN 65 PRO 66 -0.0001

PRO 66 ALA 67 0.0094

ALA 67 LYS 68 0.0002

LYS 68 ALA 69 -0.0003

ALA 69 CYS 70 0.0000

CYS 70 GLN 71 0.0000

GLN 71 PRO 72 -0.0001

PRO 72 LEU 73 0.0003

LEU 73 GLY 74 0.0001

GLY 74 ALA 75 -0.0003

ALA 75 VAL 76 -0.0001

VAL 76 LEU 77 0.0004

LEU 77 CYS 78 -0.0004

CYS 78 ALA 79 0.0001

ALA 79 LEU 80 0.0037

LEU 80 GLY 81 0.0000

GLY 81 PHE 82 -0.0000

PHE 82 GLU 83 0.0001

GLU 83 LYS 84 0.0000

LYS 84 THR 85 0.0002

THR 85 MET 86 0.0003

MET 86 PRO 87 0.0001

PRO 87 TYR 88 -0.0001

TYR 88 VAL 89 -0.0001

VAL 89 HIS 90 0.0000

HIS 90 GLY 91 -0.0005

GLY 91 SER 92 0.0002

SER 92 GLN 93 0.0012

GLN 93 GLY 94 -0.0003

GLY 94 CYS 95 -0.0001

CYS 95 VAL 96 -0.0002

VAL 96 ALA 97 -0.0001

ALA 97 TYR 98 -0.0001

TYR 98 PHE 99 0.0001

PHE 99 ARG 100 0.0000

ARG 100 SER 101 -0.0002

SER 101 TYR 102 -0.0001

TYR 102 PHE 103 0.0003

PHE 103 ASN 104 -0.0003

ASN 104 ARG 105 0.0000

ARG 105 HIS 106 0.0021

HIS 106 PHE 107 -0.0001

PHE 107 ARG 108 -0.0005

ARG 108 GLU 109 -0.0001

GLU 109 PRO 110 -0.0003

PRO 110 VAL 111 -0.0001

VAL 111 SER 112 0.0005

SER 112 CYS 113 0.0002

CYS 113 VAL 114 0.0002

VAL 114 SER 115 -0.0001

SER 115 ASP 116 -0.0001

ASP 116 SER 117 0.0000

SER 117 MET 118 0.0002

MET 118 THR 119 0.0066

THR 119 GLU 120 0.0003

GLU 120 ASP 121 0.0003

ASP 121 ALA 122 -0.0001

ALA 122 ALA 123 -0.0001

ALA 123 VAL 124 0.0001

VAL 124 PHE 125 0.0001

PHE 125 GLY 126 0.0003

GLY 126 GLY 127 -0.0001

GLY 127 GLN 128 -0.0003

GLN 128 GLN 129 -0.0001

GLN 129 ASN 130 0.0001

ASN 130 MET 131 0.0004

MET 131 LYS 132 -0.0018

LYS 132 ASP 133 0.0001

ASP 133 GLY 134 -0.0000

GLY 134 LEU 135 0.0000

LEU 135 GLN 136 -0.0001

GLN 136 ASN 137 -0.0004

ASN 137 CYS 138 -0.0003

CYS 138 LYS 139 0.0002

LYS 139 ALA 140 0.0002

ALA 140 THR 141 0.0002

THR 141 TYR 142 0.0000

TYR 142 LYS 143 -0.0002

LYS 143 PRO 144 -0.0001

PRO 144 ASP 145 0.0006

ASP 145 MET 146 0.0001

MET 146 ILE 147 -0.0002

ILE 147 ALA 148 -0.0001

ALA 148 VAL 149 0.0001

VAL 149 SER 150 -0.0005

SER 150 THR 151 0.0001

THR 151 THR 152 0.0001

THR 152 CYS 153 -0.0001

CYS 153 MET 154 -0.0001

MET 154 ALA 155 0.0001

ALA 155 GLU 156 -0.0002

GLU 156 VAL 157 0.0002

VAL 157 ILE 158 -0.0074

ILE 158 GLY 159 0.0001

GLY 159 ASP 160 0.0002

ASP 160 ASP 161 0.0001

ASP 161 LEU 162 0.0000

LEU 162 ASN 163 0.0001

ASN 163 ALA 164 -0.0000

ALA 164 PHE 165 -0.0000

PHE 165 ILE 166 -0.0002

ILE 166 ASN 167 0.0002

ASN 167 ASN 168 0.0001

ASN 168 SER 169 0.0002

SER 169 LYS 170 0.0003

LYS 170 LYS 171 -0.0003

LYS 171 GLU 172 0.0003

GLU 172 GLY 173 -0.0002

GLY 173 PHE 174 -0.0003

PHE 174 ILE 175 0.0002

ILE 175 PRO 176 0.0000

PRO 176 ASP 177 -0.0001

ASP 177 GLU 178 0.0000

GLU 178 PHE 179 0.0003

PHE 179 PRO 180 0.0002

PRO 180 VAL 181 -0.0003

VAL 181 PRO 182 -0.0000

PRO 182 PHE 183 -0.0002

PHE 183 ALA 184 -0.0093

ALA 184 HIS 185 0.0001

HIS 185 THR 186 0.0002

THR 186 PRO 187 -0.0000

PRO 187 SER 188 0.0002

SER 188 PHE 189 0.0003

PHE 189 VAL 190 0.0000

VAL 190 GLY 191 0.0000

GLY 191 SER 192 0.0003

SER 192 HIS 193 0.0002

HIS 193 VAL 194 0.0002

VAL 194 THR 195 -0.0001

THR 195 GLY 196 0.0001

GLY 196 TRP 197 0.0125

TRP 197 ASP 198 -0.0002

ASP 198 ASN 199 -0.0002

ASN 199 MET 200 -0.0001

MET 200 PHE 201 0.0001

PHE 201 GLU 202 -0.0001

GLU 202 GLY 203 -0.0001

GLY 203 ILE 204 0.0003

ILE 204 ALA 205 0.0002

ALA 205 ARG 206 0.0002

ARG 206 TYR 207 -0.0001

TYR 207 PHE 208 0.0002

PHE 208 THR 209 -0.0000

THR 209 LEU 210 0.0000

LEU 210 LYS 211 0.0001

LYS 211 SER 212 -0.0001

SER 212 MET 213 -0.0001

MET 213 ASP 214 -0.0005

ASP 214 ASP 215 0.0000

ASP 215 LYS 216 -0.0000

LYS 216 VAL 217 -0.0001

VAL 217 VAL 218 -0.0000

VAL 218 GLY 219 0.0000

GLY 219 SER 220 0.0002

SER 220 ASN 221 -0.0003

ASN 221 LYS 222 0.0001

LYS 222 LYS 223 -0.0049

LYS 223 ILE 224 0.0006

ILE 224 ASN 225 -0.0002

ASN 225 ILE 226 -0.0002

ILE 226 VAL 227 0.0004

VAL 227 PRO 228 0.0003

PRO 228 GLY 229 -0.0001

GLY 229 PHE 230 0.0000

PHE 230 GLU 231 0.0001

GLU 231 THR 232 0.0004

THR 232 TYR 233 0.0000

TYR 233 LEU 234 0.0001

LEU 234 GLY 235 -0.0002

GLY 235 ASN 236 -0.0112

ASN 236 PHE 237 -0.0000

PHE 237 ARG 238 -0.0003

ARG 238 VAL 239 0.0000

VAL 239 ILE 240 0.0004

ILE 240 LYS 241 -0.0004

LYS 241 ARG 242 -0.0000

ARG 242 MET 243 0.0000

MET 243 LEU 244 0.0001

LEU 244 SER 245 0.0004

SER 245 GLU 246 0.0001

GLU 246 MET 247 -0.0003

MET 247 GLY 248 -0.0004

GLY 248 VAL 249 0.0414

VAL 249 GLY 250 0.0003

GLY 250 TYR 251 -0.0003

TYR 251 SER 252 0.0002

SER 252 LEU 253 -0.0001

LEU 253 LEU 254 -0.0001

LEU 254 SER 255 -0.0002

SER 255 ASP 256 -0.0002

ASP 256 PRO 257 0.0002

PRO 257 GLU 258 0.0002

GLU 258 GLU 259 0.0003

GLU 259 VAL 260 0.0005

VAL 260 LEU 261 -0.0002

LEU 261 ASP 262 0.0270

ASP 262 THR 263 0.0002

THR 263 PRO 264 0.0000

PRO 264 ALA 265 0.0003

ALA 265 ASP 266 -0.0000

ASP 266 GLY 267 0.0002

GLY 267 GLN 268 -0.0002

GLN 268 PHE 269 0.0000

PHE 269 ARG 270 0.0000

ARG 270 MET 271 -0.0001

MET 271 TYR 272 0.0001

TYR 272 ALA 273 0.0004

ALA 273 GLY 274 -0.0002

GLY 274 GLY 275 0.0118

GLY 275 THR 276 -0.0002

THR 276 THR 277 -0.0002

THR 277 GLN 278 -0.0000

GLN 278 GLU 279 -0.0001

GLU 279 GLU 280 0.0002

GLU 280 MET 281 0.0004

MET 281 LYS 282 -0.0004

LYS 282 ASP 283 0.0002

ASP 283 ALA 284 0.0000

ALA 284 PRO 285 0.0001

PRO 285 ASN 286 0.0002

ASN 286 ALA 287 -0.0004

ALA 287 LEU 288 0.0076

LEU 288 ASN 289 0.0002

ASN 289 THR 290 -0.0001

THR 290 VAL 291 0.0004

VAL 291 LEU 292 0.0001

LEU 292 LEU 293 -0.0002

LEU 293 GLN 294 -0.0004

GLN 294 PRO 295 -0.0002

PRO 295 TRP 296 -0.0001

TRP 296 HIS 297 -0.0006

HIS 297 LEU 298 0.0001

LEU 298 GLU 299 0.0003

GLU 299 LYS 300 -0.0002

LYS 300 THR 301 -0.0120

THR 301 LYS 302 -0.0000

LYS 302 LYS 303 -0.0004

LYS 303 PHE 304 0.0001

PHE 304 VAL 305 0.0002

VAL 305 GLU 306 0.0002

GLU 306 GLY 307 -0.0000

GLY 307 THR 308 -0.0000

THR 308 TRP 309 -0.0004

TRP 309 LYS 310 0.0003

LYS 310 HIS 311 -0.0001

HIS 311 GLU 312 -0.0001

GLU 312 VAL 313 -0.0002

VAL 313 PRO 314 0.0157

PRO 314 LYS 315 -0.0002

LYS 315 LEU 316 0.0000

LEU 316 ASN 317 0.0003

ASN 317 ILE 318 0.0002

ILE 318 PRO 319 0.0002

PRO 319 MET 320 0.0003

MET 320 GLY 321 -0.0004

GLY 321 LEU 322 0.0002

LEU 322 ASP 323 0.0000

ASP 323 TRP 324 -0.0001

TRP 324 THR 325 -0.0000

THR 325 ASP 326 0.0003

ASP 326 GLU 327 -0.0115

GLU 327 PHE 328 -0.0005

PHE 328 LEU 329 -0.0001

LEU 329 MET 330 -0.0003

MET 330 LYS 331 0.0000

LYS 331 VAL 332 -0.0001

VAL 332 SER 333 -0.0003

SER 333 GLU 334 -0.0002

GLU 334 ILE 335 -0.0002

ILE 335 SER 336 -0.0003

SER 336 GLY 337 -0.0005

GLY 337 GLN 338 -0.0000

GLN 338 PRO 339 0.0002

PRO 339 ILE 340 0.0351

ILE 340 PRO 341 0.0003

PRO 341 ALA 342 -0.0003

ALA 342 SER 343 0.0000

SER 343 LEU 344 0.0000

LEU 344 THR 345 0.0003

THR 345 LYS 346 -0.0005

LYS 346 GLU 347 -0.0002

GLU 347 ARG 348 0.0001

ARG 348 GLY 349 0.0003

GLY 349 ARG 350 0.0001

ARG 350 LEU 351 0.0004

LEU 351 VAL 352 -0.0001

VAL 352 ASP 353 -0.0056

ASP 353 MET 354 -0.0000

MET 354 MET 355 0.0003

MET 355 THR 356 0.0004

THR 356 ASP 357 0.0004

ASP 357 SER 358 -0.0003

SER 358 HIS 359 -0.0001

HIS 359 THR 360 -0.0001

THR 360 TRP 361 -0.0002

TRP 361 LEU 362 -0.0004

LEU 362 HIS 363 -0.0002

HIS 363 GLY 364 0.0003

GLY 364 LYS 365 -0.0002

LYS 365 ARG 366 -0.0516

ARG 366 PHE 367 -0.0001

PHE 367 ALA 368 0.0004

ALA 368 LEU 369 0.0002

LEU 369 TRP 370 -0.0002

TRP 370 GLY 371 0.0000

GLY 371 ASP 372 0.0001

ASP 372 PRO 373 -0.0001

PRO 373 ASP 374 -0.0001

ASP 374 PHE 375 -0.0002

PHE 375 VAL 376 0.0004

VAL 376 MET 377 -0.0002

MET 377 GLY 378 0.0001

GLY 378 LEU 379 -0.0042

LEU 379 VAL 380 0.0001

VAL 380 LYS 381 0.0002

LYS 381 PHE 382 -0.0001

PHE 382 LEU 383 0.0001

LEU 383 LEU 384 -0.0004

LEU 384 GLU 385 -0.0000

GLU 385 LEU 386 -0.0002

LEU 386 GLY 387 0.0002

GLY 387 CYS 388 -0.0002

CYS 388 GLU 389 -0.0002

GLU 389 PRO 390 0.0002

PRO 390 VAL 391 -0.0002

VAL 391 HIS 392 -0.0107

HIS 392 ILE 393 0.0003

ILE 393 LEU 394 -0.0003

LEU 394 CYS 395 0.0002

CYS 395 HIS 396 -0.0005

HIS 396 ASN 397 -0.0001

ASN 397 GLY 398 -0.0003

GLY 398 ASN 399 0.0002

ASN 399 LYS 400 -0.0004

LYS 400 ARG 401 -0.0004

ARG 401 TRP 402 0.0001

TRP 402 LYS 403 0.0002

LYS 403 LYS 404 0.0001

LYS 404 ALA 405 0.0026

ALA 405 VAL 406 0.0001

VAL 406 ASP 407 0.0000

ASP 407 ALA 408 0.0001

ALA 408 ILE 409 0.0003

ILE 409 LEU 410 -0.0002

LEU 410 ALA 411 0.0001

ALA 411 ALA 412 -0.0002

ALA 412 SER 413 -0.0002

SER 413 PRO 414 0.0002

PRO 414 TYR 415 0.0001

TYR 415 GLY 416 -0.0001

GLY 416 LYS 417 0.0001

LYS 417 ASN 418 0.0073

ASN 418 ALA 419 0.0003

ALA 419 THR 420 0.0001

THR 420 VAL 421 -0.0001

VAL 421 TYR 422 -0.0001

TYR 422 ILE 423 -0.0000

ILE 423 GLY 424 0.0002

GLY 424 LYS 425 0.0000

LYS 425 ASP 426 -0.0003

ASP 426 LEU 427 0.0001

LEU 427 TRP 428 -0.0000

TRP 428 HIS 429 0.0000

HIS 429 LEU 430 -0.0002

LEU 430 ARG 431 -0.0009

ARG 431 SER 432 -0.0003

SER 432 LEU 433 0.0002

LEU 433 VAL 434 0.0000

VAL 434 PHE 435 0.0004

PHE 435 THR 436 -0.0002

THR 436 ASP 437 -0.0001

ASP 437 LYS 438 -0.0002

LYS 438 PRO 439 -0.0002

PRO 439 ASP 440 -0.0001

ASP 440 PHE 441 0.0000

PHE 441 MET 442 0.0001

MET 442 ILE 443 0.0003

ILE 443 GLY 444 -0.0102

GLY 444 ASN 445 -0.0001

ASN 445 SER 446 0.0003

SER 446 TYR 447 -0.0004

TYR 447 GLY 448 0.0005

GLY 448 LYS 449 -0.0001

LYS 449 PHE 450 -0.0001

PHE 450 ILE 451 0.0004

ILE 451 GLN 452 -0.0000

GLN 452 ARG 453 -0.0004

ARG 453 ASP 454 -0.0002

ASP 454 THR 455 -0.0005

THR 455 LEU 456 0.0004

LEU 456 HIS 457 0.0071

HIS 457 LYS 458 0.0000

LYS 458 GLY 459 0.0004

GLY 459 LYS 460 -0.0002

LYS 460 GLU 461 0.0001

GLU 461 PHE 462 0.0004

PHE 462 GLU 463 -0.0005

GLU 463 VAL 464 0.0003

VAL 464 PRO 465 -0.0001

PRO 465 LEU 466 0.0002

LEU 466 ILE 467 -0.0001

ILE 467 ARG 468 0.0001

ARG 468 ILE 469 0.0001

ILE 469 GLY 470 -0.0235

GLY 470 PHE 471 0.0003

PHE 471 PRO 472 -0.0001

PRO 472 ILE 473 0.0002

ILE 473 PHE 474 -0.0004

PHE 474 ASP 475 0.0002

ASP 475 ARG 476 0.0003

ARG 476 HIS 477 -0.0002

HIS 477 HIS 478 0.0002

HIS 478 LEU 479 0.0003

LEU 479 HIS 480 -0.0002

HIS 480 ARG 481 0.0001

ARG 481 SER 482 -0.0002

SER 482 THR 483 -0.0197

THR 483 THR 484 0.0004

THR 484 LEU 485 0.0004

LEU 485 GLY 486 -0.0002

GLY 486 TYR 487 -0.0000

TYR 487 GLU 488 0.0001

GLU 488 GLY 489 -0.0002

GLY 489 ALA 490 -0.0003

ALA 490 MET 491 0.0001

MET 491 GLN 492 0.0001

GLN 492 ILE 493 -0.0002

ILE 493 LEU 494 -0.0003

LEU 494 THR 495 -0.0000

THR 495 THR 496 -0.0029

THR 496 LEU 497 -0.0003

LEU 497 VAL 498 -0.0002

VAL 498 ASN 499 0.0003

ASN 499 SER 500 -0.0003

SER 500 ILE 501 0.0000

ILE 501 LEU 502 0.0001

LEU 502 GLU 503 0.0002

GLU 503 ARG 504 0.0001

ARG 504 LEU 505 -0.0000

LEU 505 ASP 506 0.0001

ASP 506 GLU 507 0.0002

GLU 507 GLU 508 0.0003

GLU 508 THR 509 -0.1045

THR 509 ARG 510 0.0001

ARG 510 GLY 511 -0.0002

GLY 511 MET 512 0.0002

MET 512 GLN 513 -0.0000

GLN 513 ALA 514 -0.0004

ALA 514 THR 515 -0.0001

THR 515 ASP 516 0.0002

ASP 516 TYR 517 0.0001

TYR 517 ASN 518 0.0003

ASN 518 HIS 519 0.0004

HIS 519 ASP 520 -0.0002

ASP 520 LEU 521 0.0002

LEU 521 VAL 522 0.0092

VAL 522 ARG 523 -0.0002

ARG 523 ALA 1 -0.0196

ALA 1 MET 2 0.0002

MET 2 ARG 3 0.0002

ARG 3 GLN 4 -0.0002

GLN 4 CYS 5 0.0001

CYS 5 ALA 6 0.0004

ALA 6 ILE 7 -0.0002

ILE 7 TYR 8 -0.0000

TYR 8 GLY 9 -0.0003

GLY 9 LYS 10 -0.0001

LYS 10 GLY 11 -0.0002

GLY 11 GLY 12 -0.0001

GLY 12 ILE 13 -0.0001

ILE 13 GLY 14 0.0002

GLY 14 LYS 15 -0.0004

LYS 15 SER 16 0.0002

SER 16 THR 17 -0.0001

THR 17 THR 18 0.0001

THR 18 THR 19 -0.0001

THR 19 GLN 20 -0.0002

GLN 20 ASN 21 0.0000

ASN 21 LEU 22 -0.0000

LEU 22 VAL 23 -0.0001

VAL 23 ALA 24 -0.0001

ALA 24 ALA 25 -0.0000

ALA 25 LEU 26 0.0001

LEU 26 ALA 27 0.0032

ALA 27 GLU 28 -0.0000

GLU 28 MET 29 0.0004

MET 29 GLY 30 -0.0001

GLY 30 LYS 31 0.0001

LYS 31 LYS 32 0.0001

LYS 32 VAL 33 -0.0004

VAL 33 MET 34 0.0001

MET 34 ILE 35 0.0001

ILE 35 VAL 36 0.0000

VAL 36 GLY 37 -0.0002

GLY 37 CYS 38 -0.0002

CYS 38 ASP 39 -0.0001

ASP 39 PRO 40 0.0061

PRO 40 LYS 41 -0.0002

LYS 41 ALA 42 -0.0005

ALA 42 ASP 43 0.0002

ASP 43 SER 44 0.0002

SER 44 THR 45 0.0005

THR 45 ARG 46 -0.0001

ARG 46 LEU 47 -0.0002

LEU 47 ILE 48 -0.0002

ILE 48 LEU 49 0.0000

LEU 49 HIS 50 -0.0003

HIS 50 SER 51 -0.0002

SER 51 LYS 52 0.0001

LYS 52 ALA 53 -0.0232

ALA 53 GLN 54 -0.0003

GLN 54 ASN 55 0.0001

ASN 55 THR 56 -0.0000

THR 56 ILE 57 -0.0001

ILE 57 MET 58 0.0000

MET 58 GLU 59 0.0003

GLU 59 MET 60 0.0003

MET 60 ALA 61 0.0002

ALA 61 ALA 62 -0.0003

ALA 62 GLU 63 -0.0000

GLU 63 ALA 64 0.0000

ALA 64 GLY 65 -0.0001

GLY 65 THR 66 -0.0010

THR 66 VAL 67 0.0002

VAL 67 GLU 68 0.0002

GLU 68 ASP 69 -0.0000

ASP 69 LEU 70 0.0001

LEU 70 GLU 71 -0.0002

GLU 71 LEU 72 0.0000

LEU 72 GLU 73 0.0002

GLU 73 ASP 74 0.0001

ASP 74 VAL 75 -0.0004

VAL 75 LEU 76 -0.0001

LEU 76 LYS 77 -0.0003

LYS 77 ALA 78 0.0003

ALA 78 GLY 79 -0.0140

GLY 79 TYR 80 0.0002

TYR 80 GLY 81 -0.0002

GLY 81 GLY 82 -0.0005

GLY 82 VAL 83 -0.0000

VAL 83 LYS 84 0.0001

LYS 84 CYS 85 -0.0000

CYS 85 VAL 86 -0.0001

VAL 86 GLU 87 -0.0001

GLU 87 SER 88 0.0004

SER 88 GLY 89 -0.0000

GLY 89 GLY 90 -0.0001

GLY 90 PRO 91 -0.0002

PRO 91 GLU 92 -0.0036

GLU 92 PRO 93 -0.0001

PRO 93 GLY 94 0.0002

GLY 94 VAL 95 -0.0002

VAL 95 GLY 96 0.0002

GLY 96 CYS 97 0.0002

CYS 97 ALA 98 0.0002

ALA 98 GLY 99 -0.0001

GLY 99 ARG 100 -0.0003

ARG 100 GLY 101 0.0001

GLY 101 VAL 102 -0.0001

VAL 102 ILE 103 -0.0002

ILE 103 THR 104 -0.0002

THR 104 ALA 105 -0.0002

ALA 105 ILE 106 -0.0003

ILE 106 ASN 107 0.0003

ASN 107 PHE 108 -0.0002

PHE 108 LEU 109 0.0006

LEU 109 GLU 110 -0.0001

GLU 110 GLU 111 -0.0003

GLU 111 GLU 112 -0.0001

GLU 112 GLY 113 0.0002

GLY 113 ALA 114 -0.0002

ALA 114 TYR 115 0.0002

TYR 115 GLU 116 0.0004

GLU 116 ASP 117 0.0000

ASP 117 ASP 118 0.0026

ASP 118 LEU 119 0.0001

LEU 119 ASP 120 0.0002

ASP 120 PHE 121 -0.0002

PHE 121 VAL 122 -0.0000

VAL 122 PHE 123 0.0001

PHE 123 TYR 124 -0.0003

TYR 124 ASP 125 -0.0003

ASP 125 VAL 126 0.0001

VAL 126 LEU 127 -0.0003

LEU 127 GLY 128 0.0001

GLY 128 ASP 129 -0.0000

ASP 129 VAL 130 -0.0000

VAL 130 VAL 131 0.0022

VAL 131 CYS 132 0.0002

CYS 132 GLY 133 -0.0003

GLY 133 GLY 134 0.0001

GLY 134 PHE 135 -0.0002

PHE 135 ALA 136 -0.0001

ALA 136 MET 137 -0.0000

MET 137 PRO 138 0.0000

PRO 138 ILE 139 0.0001

ILE 139 ARG 140 0.0003

ARG 140 GLU 141 -0.0001

GLU 141 ASN 142 -0.0003

ASN 142 LYS 143 -0.0003

LYS 143 ALA 144 -0.0314

ALA 144 GLN 145 0.0003

GLN 145 GLU 146 -0.0002

GLU 146 ILE 147 0.0002

ILE 147 TYR 148 -0.0002

TYR 148 ILE 149 0.0003

ILE 149 VAL 150 -0.0000

VAL 150 CYS 151 -0.0001

CYS 151 SER 152 -0.0002

SER 152 GLY 153 0.0000

GLY 153 GLU 154 -0.0001

GLU 154 MET 155 -0.0001

MET 155 MET 156 0.0001

MET 156 ALA 157 -0.0026

ALA 157 MET 158 0.0001

MET 158 TYR 159 -0.0005

TYR 159 ALA 160 0.0000

ALA 160 ALA 161 0.0000

ALA 161 ASN 162 0.0003

ASN 162 ASN 163 -0.0002

ASN 163 ILE 164 -0.0001

ILE 164 SER 165 0.0001

SER 165 LYS 166 0.0000

LYS 166 GLY 167 -0.0001

GLY 167 ILE 168 0.0001

ILE 168 VAL 169 -0.0001

VAL 169 LYS 170 -0.0168

LYS 170 TYR 171 -0.0003

TYR 171 ALA 172 -0.0002

ALA 172 ASN 173 -0.0001

ASN 173 SER 174 -0.0000

SER 174 GLY 175 0.0001

GLY 175 SER 176 -0.0001

SER 176 VAL 177 -0.0001

VAL 177 ARG 178 0.0002

ARG 178 LEU 179 0.0000

LEU 179 GLY 180 0.0001

GLY 180 GLY 181 0.0002

GLY 181 LEU 182 -0.0006

LEU 182 ILE 183 -0.0122

ILE 183 CYS 184 -0.0002

CYS 184 ASN 185 0.0003

ASN 185 SER 186 -0.0002

SER 186 ARG 187 0.0001

ARG 187 ASN 188 -0.0003

ASN 188 THR 189 -0.0001

THR 189 ASP 190 -0.0000

ASP 190 ARG 191 -0.0002

ARG 191 GLU 192 -0.0002

GLU 192 ASP 193 0.0000

ASP 193 GLU 194 0.0001

GLU 194 LEU 195 -0.0002

LEU 195 ILE 196 -0.0018

ILE 196 ILE 197 -0.0002

ILE 197 ALA 198 0.0001

ALA 198 LEU 199 0.0002

LEU 199 ALA 200 0.0001

ALA 200 ASN 201 0.0001

ASN 201 LYS 202 -0.0003

LYS 202 LEU 203 -0.0001

LEU 203 GLY 204 -0.0004

GLY 204 THR 205 0.0000

THR 205 GLN 206 -0.0001

GLN 206 MET 207 -0.0002

MET 207 ILE 208 0.0001

ILE 208 HIS 209 -0.0033

HIS 209 PHE 210 0.0000

PHE 210 VAL 211 -0.0003

VAL 211 PRO 212 -0.0001

PRO 212 ARG 213 -0.0002

ARG 213 ASP 214 0.0000

ASP 214 ASN 215 0.0001

ASN 215 VAL 216 0.0003

VAL 216 VAL 217 -0.0003

VAL 217 GLN 218 -0.0006

GLN 218 ARG 219 -0.0001

ARG 219 ALA 220 0.0001

ALA 220 GLU 221 -0.0002

GLU 221 ILE 222 0.0025

ILE 222 ARG 223 -0.0000

ARG 223 ARG 224 0.0001

ARG 224 MET 225 0.0000

MET 225 THR 226 0.0002

THR 226 VAL 227 -0.0001

VAL 227 ILE 228 0.0004

ILE 228 GLU 229 0.0003

GLU 229 TYR 230 0.0001

TYR 230 ASP 231 -0.0005

ASP 231 PRO 232 -0.0001

PRO 232 LYS 233 0.0001

LYS 233 ALA 234 0.0002

ALA 234 LYS 235 -0.0014

LYS 235 GLN 236 0.0000

GLN 236 ALA 237 -0.0001

ALA 237 ASP 238 0.0003

ASP 238 GLU 239 0.0001

GLU 239 TYR 240 -0.0004

TYR 240 ARG 241 0.0004

ARG 241 ALA 242 -0.0001

ALA 242 LEU 243 0.0001

LEU 243 ALA 244 -0.0003

ALA 244 ARG 245 0.0001

ARG 245 LYS 246 -0.0000

LYS 246 VAL 247 -0.0001

VAL 247 VAL 248 0.0003

VAL 248 ASP 249 -0.0000

ASP 249 ASN 250 0.0000

ASN 250 LYS 251 0.0002

LYS 251 LEU 252 0.0000

LEU 252 LEU 253 0.0002

LEU 253 VAL 254 0.0001

VAL 254 ILE 255 -0.0003

ILE 255 PRO 256 0.0002

PRO 256 ASN 257 0.0001

ASN 257 PRO 258 -0.0001

PRO 258 ILE 259 0.0001

ILE 259 THR 260 -0.0000

THR 260 MET 261 -0.0040

MET 261 ASP 262 -0.0006

ASP 262 GLU 263 0.0000

GLU 263 LEU 264 -0.0000

LEU 264 GLU 265 0.0002

GLU 265 GLU 266 0.0004

GLU 266 LEU 267 -0.0001

LEU 267 LEU 268 0.0002

LEU 268 MET 269 -0.0002

MET 269 GLU 270 0.0001

GLU 270 PHE 271 -0.0000

PHE 271 ALA 1 0.0013

ALA 1 MET 2 0.0000

MET 2 ARG 3 0.0001

ARG 3 GLN 4 -0.0004

GLN 4 CYS 5 0.0002

CYS 5 ALA 6 0.0000

ALA 6 ILE 7 0.0002

ILE 7 TYR 8 0.0002

TYR 8 GLY 9 0.0001

GLY 9 LYS 10 0.0000

LYS 10 GLY 11 0.0004

GLY 11 GLY 12 0.0004

GLY 12 ILE 13 0.0001

ILE 13 GLY 14 -0.0014

GLY 14 LYS 15 -0.0003

LYS 15 SER 16 -0.0002

SER 16 THR 17 -0.0001

THR 17 THR 18 0.0003

THR 18 THR 19 0.0001

THR 19 GLN 20 -0.0000

GLN 20 ASN 21 -0.0001

ASN 21 LEU 22 -0.0001

LEU 22 VAL 23 0.0002

VAL 23 ALA 24 0.0001

ALA 24 ALA 25 0.0004

ALA 25 LEU 26 -0.0001

LEU 26 ALA 27 0.0001

ALA 27 GLU 28 0.0002

GLU 28 MET 29 0.0000

MET 29 GLY 30 -0.0002

GLY 30 LYS 31 0.0004

LYS 31 LYS 32 -0.0002

LYS 32 VAL 33 0.0003

VAL 33 MET 34 -0.0002

MET 34 ILE 35 -0.0003

ILE 35 VAL 36 0.0001

VAL 36 GLY 37 0.0004

GLY 37 CYS 38 -0.0001

CYS 38 ASP 39 -0.0002

ASP 39 PRO 40 -0.0053

PRO 40 LYS 41 -0.0000

LYS 41 ALA 42 0.0001

ALA 42 ASP 43 0.0001

ASP 43 SER 44 -0.0002

SER 44 THR 45 0.0002

THR 45 ARG 46 0.0001

ARG 46 LEU 47 0.0002

LEU 47 ILE 48 0.0002

ILE 48 LEU 49 -0.0002

LEU 49 HIS 50 0.0005

HIS 50 SER 51 -0.0002

SER 51 LYS 52 0.0003

LYS 52 ALA 53 0.0182

ALA 53 GLN 54 0.0001

GLN 54 ASN 55 -0.0001

ASN 55 THR 56 -0.0001

THR 56 ILE 57 -0.0001

ILE 57 MET 58 0.0001

MET 58 GLU 59 0.0001

GLU 59 MET 60 -0.0000

MET 60 ALA 61 0.0000

ALA 61 ALA 62 0.0001

ALA 62 GLU 63 0.0002

GLU 63 ALA 64 -0.0004

ALA 64 GLY 65 -0.0001

GLY 65 THR 66 -0.0080

THR 66 VAL 67 0.0003

VAL 67 GLU 68 -0.0003

GLU 68 ASP 69 -0.0002

ASP 69 LEU 70 -0.0002

LEU 70 GLU 71 0.0003

GLU 71 LEU 72 -0.0000

LEU 72 GLU 73 0.0001

GLU 73 ASP 74 -0.0003

ASP 74 VAL 75 0.0001

VAL 75 LEU 76 0.0002

LEU 76 LYS 77 0.0000

LYS 77 ALA 78 0.0003

ALA 78 GLY 79 0.0166

GLY 79 TYR 80 0.0001

TYR 80 GLY 81 0.0004

GLY 81 GLY 82 0.0004

GLY 82 VAL 83 -0.0002

VAL 83 LYS 84 0.0001

LYS 84 CYS 85 -0.0002

CYS 85 VAL 86 0.0001

VAL 86 GLU 87 0.0003

GLU 87 SER 88 -0.0004

SER 88 GLY 89 -0.0005

GLY 89 GLY 90 -0.0002

GLY 90 PRO 91 0.0004

PRO 91 GLU 92 0.0113

GLU 92 PRO 93 -0.0002

PRO 93 GLY 94 0.0004

GLY 94 VAL 95 -0.0002

VAL 95 GLY 96 -0.0001

GLY 96 CYS 97 0.0005

CYS 97 ALA 98 -0.0004

ALA 98 GLY 99 0.0002

GLY 99 ARG 100 -0.0000

ARG 100 GLY 101 -0.0000

GLY 101 VAL 102 0.0002

VAL 102 ILE 103 0.0001

ILE 103 THR 104 -0.0002

THR 104 ALA 105 -0.0093

ALA 105 ILE 106 -0.0002

ILE 106 ASN 107 -0.0001

ASN 107 PHE 108 -0.0003

PHE 108 LEU 109 0.0002

LEU 109 GLU 110 -0.0004

GLU 110 GLU 111 0.0001

GLU 111 GLU 112 0.0002

GLU 112 GLY 113 -0.0000

GLY 113 ALA 114 0.0000

ALA 114 TYR 115 -0.0001

TYR 115 GLU 116 -0.0001

GLU 116 ASP 117 0.0006

ASP 117 ASP 118 0.0004

ASP 118 LEU 119 -0.0004

LEU 119 ASP 120 0.0001

ASP 120 PHE 121 0.0001

PHE 121 VAL 122 -0.0002

VAL 122 PHE 123 0.0003

PHE 123 TYR 124 -0.0001

TYR 124 ASP 125 0.0001

ASP 125 VAL 126 0.0002

VAL 126 LEU 127 -0.0001

LEU 127 GLY 128 0.0000

GLY 128 ASP 129 -0.0003

ASP 129 VAL 130 0.0002

VAL 130 VAL 131 -0.0072

VAL 131 CYS 132 -0.0000

CYS 132 GLY 133 -0.0001

GLY 133 GLY 134 -0.0003

GLY 134 PHE 135 -0.0001

PHE 135 ALA 136 0.0002

ALA 136 MET 137 0.0000

MET 137 PRO 138 0.0003

PRO 138 ILE 139 -0.0002

ILE 139 ARG 140 -0.0001

ARG 140 GLU 141 -0.0003

GLU 141 ASN 142 0.0001

ASN 142 LYS 143 -0.0001

LYS 143 ALA 144 0.0235

ALA 144 GLN 145 0.0003

GLN 145 GLU 146 0.0000

GLU 146 ILE 147 -0.0001

ILE 147 TYR 148 -0.0001

TYR 148 ILE 149 0.0001

ILE 149 VAL 150 -0.0001

VAL 150 CYS 151 0.0001

CYS 151 SER 152 -0.0000

SER 152 GLY 153 -0.0005

GLY 153 GLU 154 -0.0001

GLU 154 MET 155 0.0002

MET 155 MET 156 0.0002

MET 156 ALA 157 0.0037

ALA 157 MET 158 0.0001

MET 158 TYR 159 0.0001

TYR 159 ALA 160 -0.0002

ALA 160 ALA 161 0.0001

ALA 161 ASN 162 -0.0004

ASN 162 ASN 163 -0.0002

ASN 163 ILE 164 0.0000

ILE 164 SER 165 -0.0001

SER 165 LYS 166 -0.0001

LYS 166 GLY 167 -0.0002

GLY 167 ILE 168 -0.0004

ILE 168 VAL 169 0.0002

VAL 169 LYS 170 0.0329

LYS 170 TYR 171 0.0004

TYR 171 ALA 172 -0.0001

ALA 172 ASN 173 -0.0002

ASN 173 SER 174 0.0002

SER 174 GLY 175 0.0004

GLY 175 SER 176 -0.0001

SER 176 VAL 177 0.0000

VAL 177 ARG 178 0.0000

ARG 178 LEU 179 0.0001

LEU 179 GLY 180 -0.0002

GLY 180 GLY 181 0.0002

GLY 181 LEU 182 -0.0002

LEU 182 ILE 183 0.0249

ILE 183 CYS 184 -0.0001

CYS 184 ASN 185 -0.0001

ASN 185 SER 186 0.0001

SER 186 ARG 187 0.0001

ARG 187 ASN 188 -0.0003

ASN 188 THR 189 -0.0001

THR 189 ASP 190 0.0002

ASP 190 ARG 191 0.0000

ARG 191 GLU 192 0.0002

GLU 192 ASP 193 0.0002

ASP 193 GLU 194 0.0003

GLU 194 LEU 195 -0.0000

LEU 195 ILE 196 0.0026

ILE 196 ILE 197 0.0003

ILE 197 ALA 198 0.0000

ALA 198 LEU 199 -0.0001

LEU 199 ALA 200 0.0002

ALA 200 ASN 201 -0.0005

ASN 201 LYS 202 0.0002

LYS 202 LEU 203 -0.0001

LEU 203 GLY 204 -0.0003

GLY 204 THR 205 -0.0001

THR 205 GLN 206 -0.0002

GLN 206 MET 207 0.0000

MET 207 ILE 208 -0.0000

ILE 208 HIS 209 0.0048

HIS 209 PHE 210 -0.0002

PHE 210 VAL 211 0.0000

VAL 211 PRO 212 -0.0002

PRO 212 ARG 213 -0.0004

ARG 213 ASP 214 -0.0001

ASP 214 ASN 215 -0.0002

ASN 215 VAL 216 -0.0001

VAL 216 VAL 217 -0.0002

VAL 217 GLN 218 -0.0003

GLN 218 ARG 219 -0.0003

ARG 219 ALA 220 -0.0002

ALA 220 GLU 221 0.0003

GLU 221 ILE 222 -0.0006

ILE 222 ARG 223 -0.0001

ARG 223 ARG 224 -0.0001

ARG 224 MET 225 0.0003

MET 225 THR 226 -0.0001

THR 226 VAL 227 0.0003

VAL 227 ILE 228 0.0002

ILE 228 GLU 229 -0.0001

GLU 229 TYR 230 0.0001

TYR 230 ASP 231 0.0001

ASP 231 PRO 232 0.0000

PRO 232 LYS 233 0.0000

LYS 233 ALA 234 -0.0001

ALA 234 LYS 235 0.0031

LYS 235 GLN 236 -0.0003

GLN 236 ALA 237 0.0003

ALA 237 ASP 238 0.0001

ASP 238 GLU 239 -0.0001

GLU 239 TYR 240 0.0003

TYR 240 ARG 241 -0.0000

ARG 241 ALA 242 0.0002

ALA 242 LEU 243 -0.0002

LEU 243 ALA 244 -0.0001

ALA 244 ARG 245 -0.0001

ARG 245 LYS 246 -0.0001

LYS 246 VAL 247 -0.0001

VAL 247 VAL 248 0.0013

VAL 248 ASP 249 -0.0000

ASP 249 ASN 250 -0.0001

ASN 250 LYS 251 0.0002

LYS 251 LEU 252 0.0001

LEU 252 LEU 253 0.0001

LEU 253 VAL 254 0.0001

VAL 254 ILE 255 0.0000

ILE 255 PRO 256 0.0003

PRO 256 ASN 257 0.0002

ASN 257 PRO 258 0.0002

PRO 258 ILE 259 -0.0003

ILE 259 THR 260 0.0001

THR 260 MET 261 0.0108

MET 261 ASP 262 0.0001

ASP 262 GLU 263 -0.0002

GLU 263 LEU 264 -0.0002

LEU 264 GLU 265 -0.0001

GLU 265 GLU 266 -0.0001

GLU 266 LEU 267 -0.0002

LEU 267 LEU 268 0.0002

LEU 268 MET 269 -0.0003

MET 269 GLU 270 -0.0002

GLU 270 PHE 271 0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** doused_J6172_17 ***

CA strain for 2602182336223344808

--- normal mode 8 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* doused_J6172_17 *