Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* HORMONE 14-JAN-23 8I2H *

CA distance fluctuations for 2602241749261548099

--- normal mode 8 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
SER 515 0.17 TYR 362 -0.45 SER 427

SER 515 0.13 ASN 363 -0.26 SER 427

SER 515 0.11 ILE 364 -0.21 SER 427

ILE 516 0.12 LEU 365 -0.26 SER 427

LYS 643 0.12 ARG 366 -0.16 SER 427

SER 642 0.10 VAL 367 -0.09 SER 427

PRO 559 0.10 LEU 368 -0.12 SER 427

LYS 643 0.11 ILE 369 -0.11 SER 427

LEU 641 0.19 TRP 370 -0.05 LEU 416

PHE 624 0.21 PHE 371 -0.06 ILE 413

PHE 371 0.16 ILE 372 -0.09 LEU 375

PHE 624 0.18 SER 373 -0.07 ILE 413

PHE 624 0.24 ILE 374 -0.10 ILE 413

PHE 624 0.32 LEU 375 -0.09 ILE 372

PHE 624 0.23 ALA 376 -0.06 LEU 409

SER 420 0.24 ILE 377 -0.12 LEU 409

SER 420 0.27 THR 378 -0.09 ILE 381

ILE 628 0.27 GLY 379 -0.13 CYS 620

SER 420 0.20 ASN 380 -0.09 CYS 620

SER 420 0.27 ILE 381 -0.09 THR 378

HIS 424 0.26 ILE 382 -0.10 CYS 620

GLY 441 0.20 VAL 383 -0.10 PRO 623

GLY 441 0.25 LEU 384 -0.06 ALA 621

GLY 441 0.27 VAL 385 -0.08 ALA 621

GLY 441 0.24 ILE 386 -0.07 ALA 621

GLY 441 0.21 LEU 387 -0.06 THR 580

ALA 440 0.25 THR 388 -0.04 VAL 385

ALA 440 0.26 THR 389 -0.06 ILE 628

GLY 441 0.21 SER 390 -0.06 THR 580

HIS 424 0.20 GLN 391 -0.06 MET 576

HIS 424 0.17 TYR 392 -0.07 MET 576

ALA 440 0.15 LYS 393 -0.05 MET 576

ALA 440 0.15 LEU 394 -0.04 THR 580

SER 566 0.15 THR 395 -0.05 LEU 577

SER 566 0.12 VAL 396 -0.05 HIS 430

SER 566 0.16 PRO 397 -0.06 ASN 632

SER 566 0.17 ARG 398 -0.06 THR 580

SER 566 0.13 PHE 399 -0.04 ILE 381

SER 566 0.13 LEU 400 -0.06 HIS 430

SER 566 0.16 MET 401 -0.05 HIS 430

SER 566 0.15 CYS 402 -0.06 ILE 381

GLY 441 0.12 ASN 403 -0.05 THR 378

SER 566 0.11 LEU 404 -0.07 HIS 430

GLY 441 0.15 ALA 405 -0.05 THR 378

LEU 384 0.19 PHE 406 -0.08 ILE 377

LYS 643 0.13 ALA 407 -0.07 ILE 374

GLY 441 0.12 ASP 408 -0.05 HIS 430

GLY 441 0.20 LEU 409 -0.12 ILE 377

LYS 643 0.21 CYS 410 -0.10 ILE 374

LYS 643 0.16 ILE 411 -0.07 ILE 374

LEU 641 0.19 GLY 412 -0.09 ILE 374

LEU 641 0.26 ILE 413 -0.10 ILE 374

LYS 643 0.24 TYR 414 -0.08 PHE 448

LYS 643 0.19 LEU 415 -0.07 SER 427

LEU 641 0.26 LEU 416 -0.05 PHE 448

LYS 643 0.29 LEU 417 -0.05 PHE 448

LYS 643 0.23 ILE 418 -0.09 ILE 588

LYS 643 0.23 ALA 419 -0.09 ILE 609

LEU 641 0.34 SER 420 -0.13 SER 605

LYS 643 0.31 VAL 421 -0.18 SER 605

LYS 643 0.25 ASP 422 -0.28 SER 605

LYS 643 0.29 ILE 423 -0.26 SER 605

LYS 643 0.38 HIS 424 -0.28 SER 605

LYS 643 0.32 THR 425 -0.39 SER 605

LYS 643 0.27 LYS 426 -0.49 SER 605

LYS 643 0.24 SER 427 -0.65 SER 605

LYS 643 0.28 GLN 428 -0.54 SER 605

LYS 643 0.25 TYR 429 -0.55 VAL 604

LYS 643 0.23 HIS 430 -0.64 VAL 604

LYS 643 0.31 ASN 431 -0.47 VAL 604

LYS 643 0.32 TYR 432 -0.32 VAL 604

LYS 643 0.26 ALA 433 -0.35 VAL 604

LYS 643 0.28 ILE 434 -0.24 ALA 595

LYS 643 0.33 ASP 435 -0.18 VAL 604

LYS 643 0.30 TRP 436 -0.16 VAL 604

LYS 643 0.26 GLN 437 -0.17 ALA 592

LYS 643 0.27 THR 438 -0.13 ALA 592

LYS 643 0.32 GLY 439 -0.11 ALA 592

LYS 643 0.33 ALA 440 -0.08 ALA 592

LYS 643 0.34 GLY 441 -0.08 ALA 592

LYS 643 0.27 CYS 442 -0.12 HIS 430

LYS 643 0.26 ASP 443 -0.11 HIS 430

LYS 643 0.30 ALA 444 -0.07 ASN 538

LYS 643 0.26 ALA 445 -0.10 HIS 430

LYS 643 0.21 GLY 446 -0.17 HIS 430

LYS 643 0.22 PHE 447 -0.13 HIS 430

LYS 643 0.22 PHE 448 -0.08 HIS 430

LYS 643 0.17 THR 449 -0.14 HIS 430

VAL 531 0.17 VAL 450 -0.17 HIS 430

LYS 643 0.16 PHE 451 -0.12 HIS 430

LYS 643 0.14 ALA 452 -0.11 HIS 430

VAL 531 0.12 SER 453 -0.17 HIS 430

LEU 534 0.13 GLU 454 -0.16 HIS 430

THR 388 0.11 LEU 455 -0.12 HIS 430

LYS 643 0.08 SER 456 -0.13 HIS 430

LYS 643 0.05 VAL 457 -0.18 HIS 430

THR 388 0.07 TYR 458 -0.15 HIS 430

THR 388 0.06 THR 459 -0.12 HIS 430

PHE 371 0.05 LEU 460 -0.14 HIS 430

PHE 371 0.04 THR 461 -0.16 HIS 430

THR 388 0.04 ALA 462 -0.13 HIS 430

LEU 375 0.06 ILE 463 -0.11 HIS 430

LEU 375 0.07 THR 464 -0.14 HIS 430

LEU 375 0.05 LEU 465 -0.15 HIS 430

LEU 375 0.05 GLU 466 -0.12 HIS 430

LEU 375 0.09 ARG 467 -0.11 HIS 430

LEU 375 0.08 TRP 468 -0.14 HIS 430

LEU 375 0.06 HIS 469 -0.13 HIS 430

LEU 375 0.08 THR 470 -0.10 HIS 430

LEU 375 0.10 ILE 471 -0.12 VAL 536

LEU 375 0.08 THR 472 -0.16 SER 533

LEU 375 0.07 HIS 473 -0.14 SER 533

LEU 375 0.10 ALA 474 -0.11 LEU 529

SER 564 0.11 MET 475 -0.11 LEU 529

SER 564 0.08 GLN 476 -0.09 LEU 529

PRO 397 0.10 LEU 477 -0.07 HIS 430

LEU 375 0.06 ASP 478 -0.09 HIS 430

LEU 375 0.04 CYS 479 -0.11 HIS 430

SER 564 0.05 LYS 480 -0.10 HIS 430

SER 564 0.04 VAL 481 -0.08 HIS 430

SER 564 0.06 GLN 482 -0.06 HIS 430

ALA 440 0.08 LEU 483 -0.04 ILE 381

ALA 440 0.07 ARG 484 -0.05 ILE 381

SER 566 0.05 HIS 485 -0.07 HIS 430

SER 566 0.07 ALA 486 -0.07 HIS 430

SER 566 0.08 ALA 487 -0.05 ILE 377

LYS 643 0.06 SER 488 -0.06 HIS 430

THR 388 0.06 VAL 489 -0.09 HIS 430

THR 388 0.10 MET 490 -0.07 HIS 430

THR 388 0.12 VAL 491 -0.07 ILE 374

THR 388 0.10 MET 492 -0.09 HIS 430

THR 388 0.10 GLY 493 -0.11 HIS 430

THR 388 0.15 TRP 494 -0.08 HIS 430

THR 388 0.14 ILE 495 -0.08 HIS 430

SER 533 0.14 PHE 496 -0.12 HIS 430

TYR 530 0.14 ALA 497 -0.12 HIS 430

THR 388 0.19 PHE 498 -0.10 HIS 430

LYS 643 0.17 ALA 499 -0.11 HIS 430

TYR 530 0.20 ALA 500 -0.15 HIS 430

LYS 643 0.18 ALA 501 -0.14 HIS 430

LYS 643 0.21 LEU 502 -0.12 HIS 430

LYS 643 0.18 PHE 503 -0.15 HIS 430

LYS 643 0.19 PRO 504 -0.17 HIS 430

LYS 643 0.23 ILE 505 -0.11 HIS 430

LYS 643 0.21 PHE 506 -0.12 GLY 547

LYS 643 0.20 GLY 507 -0.15 HIS 430

LYS 643 0.17 ILE 508 -0.18 HIS 430

LYS 643 0.17 SER 509 -0.24 HIS 430

LYS 643 0.19 SER 510 -0.24 HIS 430

LYS 643 0.19 TYR 511 -0.24 HIS 430

LYS 643 0.21 MET 512 -0.27 HIS 430

LYS 643 0.17 LYS 513 -0.40 HIS 430

LYS 643 0.16 VAL 514 -0.44 HIS 430

LYS 643 0.19 SER 515 -0.43 HIS 430

LYS 643 0.17 ILE 516 -0.32 HIS 430

LYS 643 0.20 CYS 517 -0.25 HIS 430

LYS 643 0.16 LEU 518 -0.29 HIS 430

LYS 643 0.15 PRO 519 -0.27 HIS 430

VAL 604 0.16 MET 520 -0.34 HIS 430

LYS 643 0.15 ASP 521 -0.34 HIS 430

VAL 604 0.14 ILE 522 -0.33 HIS 430

LYS 643 0.13 ASP 523 -0.33 HIS 430

LYS 643 0.14 SER 524 -0.27 HIS 430

LYS 643 0.13 PRO 525 -0.25 HIS 430

LYS 643 0.14 LEU 526 -0.22 HIS 430

LYS 643 0.15 SER 527 -0.25 HIS 430

ALA 500 0.13 GLN 528 -0.28 HIS 430

ALA 500 0.15 LEU 529 -0.24 HIS 430

ALA 500 0.20 TYR 530 -0.23 HIS 430

VAL 450 0.17 VAL 531 -0.27 HIS 430

ALA 497 0.12 MET 532 -0.28 HIS 430

PHE 496 0.14 SER 533 -0.24 HIS 430

ALA 497 0.13 LEU 534 -0.27 HIS 430

GLU 454 0.10 LEU 535 -0.30 HIS 430

SER 589 0.10 VAL 536 -0.27 HIS 430

MET 492 0.06 LEU 537 -0.25 HIS 430

THR 388 0.05 ASN 538 -0.27 HIS 430

LEU 540 0.09 VAL 539 -0.28 HIS 430

VAL 539 0.09 LEU 540 -0.25 HIS 430

PHE 542 0.06 ALA 541 -0.23 HIS 430

ALA 541 0.06 PHE 542 -0.24 HIS 430

VAL 544 0.10 VAL 543 -0.25 HIS 430

VAL 543 0.10 VAL 544 -0.23 VAL 536

PHE 371 0.07 ILE 545 -0.20 HIS 430

PHE 371 0.08 CYS 546 -0.22 HIS 430

PHE 371 0.07 GLY 547 -0.25 VAL 536

LEU 375 0.08 CYS 548 -0.20 VAL 536

LEU 375 0.11 TYR 549 -0.17 HIS 430

LEU 375 0.11 ILE 550 -0.21 VAL 536

LEU 375 0.10 HIS 551 -0.22 VAL 536

LEU 375 0.11 ILE 552 -0.17 VAL 536

LEU 375 0.14 TYR 553 -0.16 VAL 536

LEU 375 0.13 LEU 554 -0.20 VAL 536

LEU 375 0.12 THR 555 -0.19 VAL 536

LEU 375 0.15 VAL 556 -0.15 VAL 536

LYS 572 0.18 ARG 557 -0.16 LEU 597

LEU 375 0.15 ASN 558 -0.18 VAL 536

LEU 375 0.17 PRO 559 -0.17 LEU 597

LEU 375 0.13 ASN 560 -0.18 LEU 529

LEU 375 0.13 ILE 561 -0.16 VAL 536

LEU 375 0.14 VAL 562 -0.14 VAL 536

LEU 375 0.15 SER 563 -0.12 VAL 536

LEU 375 0.15 SER 564 -0.10 LEU 597

LEU 375 0.18 SER 565 -0.09 PHE 590

LEU 375 0.18 SER 566 -0.07 PHE 590

LEU 375 0.16 ASP 567 -0.09 VAL 536

LEU 375 0.17 THR 568 -0.12 PHE 590

LEU 375 0.20 ARG 569 -0.10 PHE 590

LEU 375 0.17 ILE 570 -0.09 ASN 632

LEU 375 0.16 ALA 571 -0.11 PHE 590

ARG 557 0.18 LYS 572 -0.13 PHE 590

LEU 375 0.19 ARG 573 -0.12 ASN 632

LEU 375 0.15 MET 574 -0.12 ARG 573

LEU 375 0.16 ALA 575 -0.14 HIS 430

LEU 375 0.19 MET 576 -0.15 PHE 579

LEU 375 0.16 LEU 577 -0.13 HIS 430

PHE 371 0.12 ILE 578 -0.17 HIS 430

PHE 371 0.14 PHE 579 -0.18 HIS 430

PHE 371 0.14 THR 580 -0.17 HIS 430

PHE 371 0.10 ASP 581 -0.20 HIS 430

PHE 371 0.09 PHE 582 -0.24 HIS 430

PHE 371 0.11 LEU 583 -0.24 HIS 430

PHE 371 0.09 CYS 584 -0.24 HIS 430

LEU 540 0.05 MET 585 -0.28 HIS 430

LEU 540 0.08 ALA 586 -0.31 HIS 430

VAL 536 0.07 PRO 587 -0.35 HIS 430

VAL 536 0.07 ILE 588 -0.36 HIS 430

VAL 536 0.10 SER 589 -0.35 HIS 430

VAL 536 0.09 PHE 590 -0.36 HIS 430

VAL 536 0.08 PHE 591 -0.42 HIS 430

MET 532 0.10 ALA 592 -0.42 HIS 430

VAL 536 0.09 ILE 593 -0.38 HIS 430

MET 532 0.09 SER 594 -0.42 HIS 430

MET 532 0.11 ALA 595 -0.47 HIS 430

ALA 595 0.11 SER 596 -0.40 HIS 430

LEU 529 0.12 LEU 597 -0.39 HIS 430

LEU 529 0.11 LYS 598 -0.45 HIS 430

LEU 529 0.09 VAL 599 -0.45 HIS 430

LEU 529 0.10 PRO 600 -0.50 HIS 430

LEU 529 0.07 LEU 601 -0.46 HIS 430

GLN 528 0.09 ILE 602 -0.49 HIS 430

GLN 528 0.12 THR 603 -0.58 HIS 430

MET 520 0.16 VAL 604 -0.64 HIS 430

MET 520 0.13 SER 605 -0.65 SER 427

GLN 528 0.10 LYS 606 -0.52 SER 427

VAL 531 0.11 ALA 607 -0.47 HIS 430

MET 520 0.12 LYS 608 -0.45 SER 427

VAL 531 0.09 ILE 609 -0.44 SER 427

VAL 531 0.10 LEU 610 -0.37 SER 427

VAL 531 0.11 LEU 611 -0.32 SER 427

VAL 531 0.09 VAL 612 -0.28 SER 427

VAL 531 0.08 LEU 613 -0.25 SER 427

PHE 371 0.09 PHE 614 -0.25 SER 427

VAL 531 0.08 HIS 615 -0.23 HIS 430

VAL 531 0.08 PRO 616 -0.15 SER 427

PHE 371 0.14 ILE 617 -0.16 SER 427

PHE 371 0.12 ASN 618 -0.15 HIS 430

ARG 557 0.09 SER 619 -0.10 HIS 430

LEU 375 0.15 CYS 620 -0.13 GLY 379

LEU 375 0.19 ALA 621 -0.10 HIS 430

LEU 375 0.17 ASN 622 -0.10 ASN 618

LEU 375 0.20 PRO 623 -0.10 VAL 383

LEU 375 0.32 PHE 624 -0.10 THR 580

LEU 375 0.24 LEU 625 -0.16 THR 580

ARG 569 0.19 TYR 626 -0.14 THR 580

GLY 379 0.20 ALA 627 -0.10 THR 580

GLY 379 0.27 ILE 628 -0.10 THR 580

LEU 375 0.24 PHE 629 -0.14 THR 580

LEU 375 0.20 THR 630 -0.15 MET 576

LEU 375 0.18 LYS 631 -0.13 PHE 579

HIS 424 0.17 ASN 632 -0.13 MET 576

SER 420 0.19 PHE 633 -0.10 PHE 579

THR 378 0.23 ARG 634 -0.11 PHE 579

HIS 424 0.22 ARG 635 -0.11 ILE 639

HIS 424 0.23 ASP 636 -0.09 PHE 579

HIS 424 0.26 PHE 637 -0.09 ILE 628

HIS 424 0.28 PHE 638 -0.10 PHE 629

HIS 424 0.28 ILE 639 -0.11 ARG 635

HIS 424 0.31 LEU 640 -0.06 PHE 629

HIS 424 0.36 LEU 641 -0.07 PHE 629

HIS 424 0.36 SER 642 -0.09 ARG 635

HIS 424 0.38 LYS 643 -0.07 ARG 635

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** HORMONE 14-JAN-23 8I2H ***

CA distance fluctuations for 2602241749261548099

--- normal mode 8 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* HORMONE 14-JAN-23 8I2H *