Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* HORMONE 14-JAN-23 8I2H *

CA distance fluctuations for 2602241749261548099

--- normal mode 9 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
LEU 641 0.16 TYR 362 -0.28 SER 427

LEU 641 0.18 ASN 363 -0.15 LYS 426

LEU 641 0.20 ILE 364 -0.09 SER 427

LEU 641 0.17 LEU 365 -0.14 SER 427

LEU 641 0.17 ARG 366 -0.17 LYS 606

LEU 641 0.21 VAL 367 -0.10 LYS 606

LEU 641 0.21 LEU 368 -0.05 ALA 592

LEU 641 0.17 ILE 369 -0.07 LYS 606

LEU 641 0.19 TRP 370 -0.09 SER 605

LEU 641 0.24 PHE 371 -0.05 ALA 592

PHE 624 0.20 ILE 372 -0.04 PHE 614

LEU 477 0.16 SER 373 -0.05 ALA 592

LEU 477 0.19 ILE 374 -0.05 ILE 413

LEU 477 0.22 LEU 375 -0.04 PRO 616

LEU 477 0.20 ALA 376 -0.04 PRO 616

LEU 477 0.19 ILE 377 -0.04 SER 566

LEU 477 0.22 THR 378 -0.04 ALA 621

LEU 477 0.24 GLY 379 -0.04 ALA 621

LEU 477 0.22 ASN 380 -0.08 SER 566

LEU 477 0.22 ILE 381 -0.09 SER 566

LEU 477 0.25 ILE 382 -0.08 SER 566

LEU 477 0.28 VAL 383 -0.11 SER 566

LEU 477 0.25 LEU 384 -0.16 SER 566

LEU 477 0.26 VAL 385 -0.14 SER 566

LEU 477 0.30 ILE 386 -0.14 SER 566

LEU 477 0.31 LEU 387 -0.22 SER 566

LEU 477 0.26 THR 388 -0.22 SER 566

LEU 477 0.27 THR 389 -0.18 SER 566

LEU 477 0.34 SER 390 -0.20 SER 566

LEU 477 0.34 GLN 391 -0.20 SER 564

LEU 477 0.43 TYR 392 -0.28 SER 565

LEU 477 0.41 LYS 393 -0.38 SER 566

LEU 477 0.36 LEU 394 -0.42 SER 566

LEU 477 0.43 THR 395 -0.54 SER 566

LEU 477 0.27 VAL 396 -0.47 SER 566

LEU 477 0.36 PRO 397 -0.45 SER 566

LEU 477 0.35 ARG 398 -0.42 SER 566

LEU 477 0.22 PHE 399 -0.36 SER 566

LEU 477 0.20 LEU 400 -0.31 SER 566

LEU 477 0.26 MET 401 -0.26 SER 566

LEU 477 0.21 CYS 402 -0.26 SER 566

LEU 477 0.14 ASN 403 -0.24 SER 566

LEU 477 0.17 LEU 404 -0.17 SER 566

LEU 477 0.20 ALA 405 -0.15 SER 566

LEU 477 0.14 PHE 406 -0.17 SER 566

LEU 477 0.11 ALA 407 -0.14 SER 566

LEU 477 0.15 ASP 408 -0.09 SER 566

LEU 477 0.15 LEU 409 -0.09 SER 566

LEU 477 0.10 CYS 410 -0.11 SER 566

LEU 477 0.10 ILE 411 -0.07 LEU 611

LEU 477 0.14 GLY 412 -0.05 LEU 611

LEU 477 0.12 ILE 413 -0.07 SER 605

LEU 477 0.08 TYR 414 -0.08 SER 605

CYS 620 0.11 LEU 415 -0.08 SER 605

LEU 477 0.13 LEU 416 -0.10 SER 605

LEU 477 0.10 LEU 417 -0.11 SER 605

PHE 624 0.10 ILE 418 -0.15 SER 605

LEU 641 0.13 ALA 419 -0.17 SER 605

LEU 641 0.14 SER 420 -0.18 SER 605

LEU 641 0.11 VAL 421 -0.20 SER 605

LEU 641 0.13 ASP 422 -0.31 SER 605

LEU 641 0.18 ILE 423 -0.29 SER 605

LEU 641 0.16 HIS 424 -0.27 SER 605

LEU 641 0.14 THR 425 -0.33 SER 605

LEU 641 0.17 LYS 426 -0.43 SER 605

SER 642 0.16 SER 427 -0.52 SER 605

LEU 641 0.14 GLN 428 -0.41 SER 605

LEU 641 0.11 TYR 429 -0.38 SER 605

LEU 641 0.10 HIS 430 -0.37 VAL 604

LEU 641 0.10 ASN 431 -0.26 VAL 604

ASP 435 0.08 TYR 432 -0.18 VAL 604

TYR 362 0.15 ALA 433 -0.19 LYS 513

TYR 362 0.15 ILE 434 -0.12 LYS 598

TYR 362 0.09 ASP 435 -0.10 LYS 480

TYR 362 0.09 TRP 436 -0.10 LYS 598

TYR 362 0.12 GLN 437 -0.17 HIS 430

TYR 362 0.11 THR 438 -0.14 LYS 480

TYR 362 0.07 GLY 439 -0.12 LYS 480

MET 585 0.06 ALA 440 -0.12 THR 388

MET 585 0.05 GLY 441 -0.10 THR 388

HIS 615 0.07 CYS 442 -0.12 HIS 430

MET 585 0.09 ASP 443 -0.14 LYS 480

MET 585 0.07 ALA 444 -0.13 THR 388

MET 585 0.07 ALA 445 -0.10 THR 388

MET 585 0.11 GLY 446 -0.16 HIS 430

MET 585 0.10 PHE 447 -0.15 LYS 480

MET 585 0.07 PHE 448 -0.13 THR 388

ASN 618 0.10 THR 449 -0.12 HIS 430

MET 585 0.12 VAL 450 -0.15 HIS 430

MET 585 0.07 PHE 451 -0.14 LYS 480

SER 619 0.06 ALA 452 -0.11 SER 566

ASP 581 0.10 SER 453 -0.13 HIS 430

PHE 542 0.10 GLU 454 -0.15 LYS 480

PHE 542 0.06 LEU 455 -0.17 SER 566

LEU 477 0.08 SER 456 -0.13 SER 566

ILE 550 0.07 VAL 457 -0.11 HIS 430

VAL 544 0.07 TYR 458 -0.17 VAL 562

LEU 477 0.07 THR 459 -0.21 SER 566

LEU 477 0.11 LEU 460 -0.14 SER 566

HIS 485 0.10 THR 461 -0.16 VAL 562

HIS 485 0.12 ALA 462 -0.23 VAL 562

LEU 477 0.15 ILE 463 -0.24 ASP 567

LEU 477 0.12 THR 464 -0.17 VAL 562

HIS 485 0.14 LEU 465 -0.23 VAL 562

TYR 626 0.11 GLU 466 -0.31 VAL 562

LEU 477 0.18 ARG 467 -0.28 VAL 562

ASN 632 0.08 TRP 468 -0.24 VAL 562

ASN 632 0.14 HIS 469 -0.30 VAL 562

ASN 632 0.22 THR 470 -0.43 VAL 562

ILE 570 0.21 ILE 471 -0.35 VAL 562

ASP 567 0.17 THR 472 -0.21 VAL 562

ASN 632 0.23 HIS 473 -0.29 VAL 562

ASP 567 0.43 ALA 474 -0.44 VAL 562

SER 566 0.41 MET 475 -0.29 VAL 562

TYR 392 0.39 GLN 476 -0.40 VAL 562

ASN 632 0.44 LEU 477 -0.59 VAL 562

THR 395 0.31 ASP 478 -0.48 VAL 562

THR 395 0.24 CYS 479 -0.32 VAL 562

THR 395 0.30 LYS 480 -0.35 VAL 562

THR 395 0.29 VAL 481 -0.41 VAL 562

THR 395 0.24 GLN 482 -0.50 VAL 562

PHE 399 0.13 LEU 483 -0.48 VAL 562

ALA 462 0.07 ARG 484 -0.42 VAL 562

LEU 465 0.14 HIS 485 -0.36 VAL 562

HIS 485 0.11 ALA 486 -0.38 VAL 562

THR 461 0.07 ALA 487 -0.34 VAL 562

VAL 544 0.07 SER 488 -0.33 VAL 562

VAL 544 0.08 VAL 489 -0.32 VAL 562

THR 459 0.06 MET 490 -0.29 VAL 562

VAL 544 0.06 VAL 491 -0.28 VAL 562

VAL 544 0.06 MET 492 -0.31 LYS 480

VAL 544 0.07 GLY 493 -0.25 LYS 480

ALA 541 0.07 TRP 494 -0.22 VAL 562

ALA 541 0.07 ILE 495 -0.25 LYS 480

ALA 541 0.08 PHE 496 -0.28 LYS 480

ALA 541 0.08 ALA 497 -0.21 LYS 480

LEU 540 0.08 PHE 498 -0.22 LYS 480

LEU 537 0.12 ALA 499 -0.26 LYS 480

ASN 538 0.14 ALA 500 -0.23 LYS 480

ASN 538 0.11 ALA 501 -0.19 LYS 480

ASN 538 0.11 LEU 502 -0.22 LYS 480

LEU 534 0.14 PHE 503 -0.24 LYS 480

MET 585 0.14 PRO 504 -0.20 LYS 480

MET 585 0.11 ILE 505 -0.20 LYS 480

SER 589 0.11 PHE 506 -0.23 LYS 480

SER 589 0.11 GLY 507 -0.23 LYS 480

SER 589 0.13 ILE 508 -0.25 LYS 480

SER 589 0.13 SER 509 -0.22 LYS 480

ILE 588 0.11 SER 510 -0.20 HIS 430

MET 585 0.11 TYR 511 -0.21 HIS 430

HIS 615 0.10 MET 512 -0.23 HIS 430

LEU 611 0.12 LYS 513 -0.31 HIS 430

VAL 612 0.12 VAL 514 -0.33 HIS 430

VAL 612 0.13 SER 515 -0.35 TYR 429

VAL 612 0.13 ILE 516 -0.24 TYR 429

HIS 615 0.11 CYS 517 -0.21 HIS 430

HIS 615 0.14 LEU 518 -0.21 HIS 430

ILE 588 0.14 PRO 519 -0.22 HIS 430

ILE 588 0.18 MET 520 -0.26 HIS 430

ILE 588 0.15 ASP 521 -0.25 HIS 430

ALA 592 0.17 ILE 522 -0.22 HIS 430

ALA 592 0.14 ASP 523 -0.21 LYS 480

ALA 592 0.12 SER 524 -0.25 LYS 480

ALA 592 0.12 PRO 525 -0.28 LYS 480

SER 589 0.10 LEU 526 -0.31 LYS 480

SER 589 0.13 SER 527 -0.27 LYS 480

ALA 592 0.15 GLN 528 -0.25 LYS 480

SER 589 0.10 LEU 529 -0.31 LYS 480

ILE 508 0.11 TYR 530 -0.30 LYS 480

SER 589 0.16 VAL 531 -0.24 LYS 480

ILE 550 0.12 MET 532 -0.24 LYS 480

PHE 503 0.13 SER 533 -0.30 LYS 480

PHE 503 0.14 LEU 534 -0.25 LYS 480

ILE 550 0.13 LEU 535 -0.20 LYS 480

ILE 550 0.13 VAL 536 -0.22 CYS 479

ALA 500 0.13 LEU 537 -0.26 CYS 479

ALA 500 0.14 ASN 538 -0.19 CYS 479

ILE 550 0.16 VAL 539 -0.17 SER 427

ILE 550 0.13 LEU 540 -0.20 CYS 479

ALA 500 0.10 ALA 541 -0.19 CYS 479

ILE 550 0.13 PHE 542 -0.12 SER 427

ILE 550 0.18 VAL 543 -0.13 HIS 473

ILE 550 0.12 VAL 544 -0.17 HIS 473

HIS 485 0.10 ILE 545 -0.10 THR 472

ILE 550 0.18 CYS 546 -0.09 SER 427

ILE 550 0.16 GLY 547 -0.12 THR 472

HIS 485 0.11 CYS 548 -0.13 THR 472

LEU 601 0.11 TYR 549 -0.05 LYS 572

VAL 543 0.18 ILE 550 -0.11 LYS 572

LEU 601 0.10 HIS 551 -0.08 THR 472

LEU 601 0.12 ILE 552 -0.10 LEU 483

LEU 601 0.19 TYR 553 -0.10 THR 395

LEU 601 0.20 LEU 554 -0.10 LEU 483

LEU 601 0.14 THR 555 -0.14 LEU 483

PHE 579 0.18 VAL 556 -0.22 LEU 483

LEU 601 0.26 ARG 557 -0.19 LEU 483

LEU 601 0.23 ASN 558 -0.20 LEU 477

LEU 601 0.24 PRO 559 -0.29 LEU 477

LEU 601 0.18 ASN 560 -0.33 LEU 477

LEU 601 0.13 ILE 561 -0.43 LEU 477

ARG 557 0.16 VAL 562 -0.59 LEU 477

LEU 583 0.14 SER 563 -0.42 LEU 483

MET 475 0.22 SER 564 -0.47 THR 395

MET 475 0.25 SER 565 -0.43 THR 395

ALA 474 0.43 SER 566 -0.54 THR 395

ALA 474 0.43 ASP 567 -0.40 VAL 396

ALA 474 0.24 THR 568 -0.30 THR 395

ALA 474 0.31 ARG 569 -0.28 THR 395

ALA 474 0.38 ILE 570 -0.34 PRO 397

ALA 474 0.28 ALA 571 -0.18 PRO 397

MET 576 0.25 LYS 572 -0.15 PRO 397

LEU 477 0.28 ARG 573 -0.10 ARG 398

LEU 477 0.24 MET 574 -0.08 LEU 400

PHE 579 0.22 ALA 575 -0.10 ILE 550

LYS 572 0.25 MET 576 -0.09 ILE 550

LEU 477 0.21 LEU 577 -0.03 ILE 550

LEU 477 0.16 ILE 578 -0.05 SER 427

LYS 572 0.25 PHE 579 -0.06 SER 427

LYS 572 0.21 THR 580 -0.05 SER 427

ARG 557 0.14 ASP 581 -0.08 SER 427

ARG 557 0.20 PHE 582 -0.11 SER 427

ARG 557 0.23 LEU 583 -0.11 SER 427

LYS 572 0.18 CYS 584 -0.12 SER 427

ARG 557 0.16 MET 585 -0.14 SER 427

ARG 557 0.22 ALA 586 -0.16 SER 427

ARG 557 0.23 PRO 587 -0.20 SER 427

MET 520 0.18 ILE 588 -0.21 SER 427

ARG 557 0.17 SER 589 -0.19 SER 427

ARG 557 0.23 PHE 590 -0.23 SER 427

ARG 557 0.21 PHE 591 -0.27 SER 427

ILE 522 0.17 ALA 592 -0.26 SER 427

ARG 557 0.18 ILE 593 -0.24 SER 427

ARG 557 0.22 SER 594 -0.28 SER 427

ARG 557 0.18 ALA 595 -0.31 SER 427

ARG 557 0.16 SER 596 -0.28 HIS 430

ARG 557 0.18 LEU 597 -0.27 HIS 430

ARG 557 0.18 LYS 598 -0.31 HIS 430

ARG 557 0.22 VAL 599 -0.32 SER 427

ARG 557 0.21 PRO 600 -0.35 SER 427

ARG 557 0.26 LEU 601 -0.35 SER 427

ARG 557 0.24 ILE 602 -0.38 SER 427

ARG 557 0.21 THR 603 -0.46 SER 427

ARG 557 0.18 VAL 604 -0.46 SER 427

ARG 557 0.18 SER 605 -0.52 SER 427

ARG 557 0.21 LYS 606 -0.42 SER 427

ARG 557 0.19 ALA 607 -0.34 SER 427

ARG 557 0.15 LYS 608 -0.32 SER 427

ARG 557 0.17 ILE 609 -0.29 SER 427

ARG 557 0.19 LEU 610 -0.25 SER 427

ARG 557 0.14 LEU 611 -0.20 SER 427

ILE 516 0.13 VAL 612 -0.15 SER 427

PHE 624 0.18 LEU 613 -0.14 SER 427

LYS 572 0.18 PHE 614 -0.14 SER 427

MET 520 0.14 HIS 615 -0.11 SER 427

LEU 477 0.13 PRO 616 -0.06 SER 427

ALA 621 0.20 ILE 617 -0.06 SER 427

LEU 477 0.17 ASN 618 -0.05 SER 427

LEU 477 0.17 SER 619 -0.04 THR 378

LEU 477 0.20 CYS 620 -0.04 THR 378

LEU 477 0.22 ALA 621 -0.04 GLY 379

LEU 477 0.24 ASN 622 -0.03 PHE 579

LEU 477 0.27 PRO 623 -0.04 PHE 406

LEU 477 0.26 PHE 624 -0.04 ILE 550

LEU 477 0.26 LEU 625 -0.05 ILE 550

LEU 477 0.32 TYR 626 -0.07 CYS 402

LEU 477 0.35 ALA 627 -0.09 CYS 402

LEU 477 0.31 ILE 628 -0.06 CYS 402

LEU 477 0.31 PHE 629 -0.07 CYS 402

LEU 477 0.37 THR 630 -0.10 CYS 402

MET 475 0.37 LYS 631 -0.11 PRO 559

LEU 477 0.44 ASN 632 -0.13 PRO 559

LEU 477 0.39 PHE 633 -0.10 PRO 559

LEU 477 0.34 ARG 634 -0.08 PRO 559

MET 475 0.36 ARG 635 -0.11 PRO 559

LEU 477 0.35 ASP 636 -0.12 PRO 559

LEU 477 0.31 PHE 637 -0.08 PRO 559

MET 475 0.30 PHE 638 -0.08 PRO 559

MET 475 0.30 ILE 639 -0.11 PRO 559

LEU 477 0.27 LEU 640 -0.09 PRO 559

MET 475 0.26 LEU 641 -0.07 PRO 559

MET 475 0.26 SER 642 -0.08 PRO 559

MET 475 0.24 LYS 643 -0.09 PRO 559

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** HORMONE 14-JAN-23 8I2H ***

CA distance fluctuations for 2602241749261548099

--- normal mode 9 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* HORMONE 14-JAN-23 8I2H *