Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* HORMONE 14-JAN-23 8I2H *

CA distance fluctuations for 2603021201203093406

--- normal mode 11 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ALA 433 0.32 TYR 362 -0.39 LYS 606

ALA 433 0.28 ASN 363 -0.28 LYS 606

SER 642 0.28 ILE 364 -0.20 LYS 606

SER 642 0.25 LEU 365 -0.27 LYS 606

SER 642 0.28 ARG 366 -0.37 SER 605

SER 642 0.32 VAL 367 -0.24 SER 605

SER 642 0.30 LEU 368 -0.17 LYS 606

LEU 641 0.27 ILE 369 -0.20 LYS 606

LEU 641 0.33 TRP 370 -0.21 SER 605

LEU 641 0.37 PHE 371 -0.14 SER 605

LEU 641 0.31 ILE 372 -0.15 LEU 477

LEU 641 0.29 SER 373 -0.16 LEU 477

LEU 641 0.36 ILE 374 -0.18 LEU 477

LEU 641 0.39 LEU 375 -0.19 LEU 477

LEU 641 0.29 ALA 376 -0.20 LEU 477

LEU 641 0.29 ILE 377 -0.22 LEU 477

LEU 641 0.38 THR 378 -0.24 LEU 477

LEU 641 0.33 GLY 379 -0.27 LEU 477

LEU 641 0.23 ASN 380 -0.27 LEU 477

LEU 641 0.25 ILE 381 -0.27 LEU 477

LEU 641 0.29 ILE 382 -0.32 LEU 477

LEU 641 0.18 VAL 383 -0.36 LEU 477

LEU 641 0.13 LEU 384 -0.33 LEU 477

LYS 643 0.17 VAL 385 -0.33 LEU 477

LEU 375 0.14 ILE 386 -0.41 LEU 477

SER 566 0.21 LEU 387 -0.43 LEU 477

SER 566 0.23 THR 388 -0.34 LEU 477

SER 566 0.21 THR 389 -0.37 LEU 477

SER 565 0.27 SER 390 -0.46 LEU 477

SER 565 0.35 GLN 391 -0.45 LEU 477

SER 566 0.43 TYR 392 -0.53 LEU 477

SER 566 0.51 LYS 393 -0.50 LEU 477

SER 566 0.44 LEU 394 -0.48 LEU 477

SER 566 0.50 THR 395 -0.61 LEU 477

SER 566 0.32 VAL 396 -0.48 LEU 477

ILE 570 0.31 PRO 397 -0.57 LEU 477

SER 566 0.31 ARG 398 -0.52 LEU 477

SER 566 0.24 PHE 399 -0.39 LEU 477

SER 566 0.17 LEU 400 -0.35 LEU 477

SER 566 0.16 MET 401 -0.38 LEU 477

SER 566 0.15 CYS 402 -0.34 LEU 477

SER 566 0.12 ASN 403 -0.27 LEU 477

SER 566 0.09 LEU 404 -0.25 LEU 477

LEU 641 0.14 ALA 405 -0.28 LEU 477

LEU 641 0.13 PHE 406 -0.25 LEU 477

LEU 641 0.13 ALA 407 -0.20 LEU 477

LEU 641 0.17 ASP 408 -0.21 LEU 477

LEU 641 0.19 LEU 409 -0.22 LEU 477

LEU 641 0.15 CYS 410 -0.19 LEU 477

LEU 641 0.17 ILE 411 -0.16 LEU 477

LEU 641 0.22 GLY 412 -0.17 LEU 477

LEU 641 0.20 ILE 413 -0.17 LEU 477

LEU 641 0.17 TYR 414 -0.15 LEU 477

LEU 641 0.22 LEU 415 -0.17 SER 605

LEU 641 0.25 LEU 416 -0.20 SER 605

LEU 641 0.20 LEU 417 -0.21 SER 605

LEU 641 0.20 ILE 418 -0.26 SER 605

SER 642 0.26 ALA 419 -0.32 SER 605

SER 642 0.27 SER 420 -0.33 SER 605

SER 642 0.23 VAL 421 -0.34 SER 605

SER 642 0.25 ASP 422 -0.53 SER 605

SER 642 0.32 ILE 423 -0.51 SER 605

SER 642 0.30 HIS 424 -0.46 SER 605

SER 642 0.27 THR 425 -0.55 SER 605

SER 642 0.31 LYS 426 -0.75 SER 605

SER 642 0.29 SER 427 -0.87 SER 605

SER 642 0.26 GLN 428 -0.64 SER 605

SER 642 0.22 TYR 429 -0.63 SER 515

ASN 363 0.21 HIS 430 -0.59 VAL 514

SER 642 0.20 ASN 431 -0.42 LYS 598

SER 642 0.18 TYR 432 -0.29 LYS 598

TYR 362 0.32 ALA 433 -0.35 LYS 513

TYR 362 0.30 ILE 434 -0.19 LYS 598

TYR 362 0.20 ASP 435 -0.15 LYS 598

TYR 362 0.19 TRP 436 -0.18 LYS 598

TYR 362 0.23 GLN 437 -0.31 HIS 430

TYR 362 0.21 THR 438 -0.16 HIS 430

TYR 362 0.15 GLY 439 -0.18 THR 388

TYR 362 0.13 ALA 440 -0.21 THR 388

TYR 362 0.12 GLY 441 -0.18 THR 388

TYR 362 0.15 CYS 442 -0.20 HIS 430

TYR 362 0.12 ASP 443 -0.21 HIS 430

TYR 362 0.10 ALA 444 -0.19 THR 388

LEU 641 0.12 ALA 445 -0.16 HIS 430

LEU 641 0.12 GLY 446 -0.25 HIS 430

LEU 641 0.10 PHE 447 -0.20 HIS 430

LEU 641 0.11 PHE 448 -0.15 HIS 430

LEU 641 0.13 THR 449 -0.18 HIS 430

LEU 641 0.11 VAL 450 -0.22 HIS 430

LEU 641 0.10 PHE 451 -0.18 HIS 430

LEU 641 0.12 ALA 452 -0.15 LEU 477

LEU 641 0.12 SER 453 -0.16 SER 427

LYS 480 0.11 GLU 454 -0.17 HIS 430

LEU 641 0.08 LEU 455 -0.14 HIS 430

LEU 641 0.09 SER 456 -0.15 LEU 477

LYS 480 0.13 VAL 457 -0.14 SER 427

LYS 480 0.14 TYR 458 -0.13 VAL 544

PHE 590 0.11 THR 459 -0.17 LEU 477

PHE 590 0.17 LEU 460 -0.15 LEU 477

PHE 590 0.20 THR 461 -0.14 ASN 632

PHE 590 0.16 ALA 462 -0.20 ASN 632

PHE 590 0.17 ILE 463 -0.23 ASN 632

PHE 590 0.22 THR 464 -0.18 ASN 632

ALA 541 0.25 LEU 465 -0.21 ASN 632

PHE 590 0.19 GLU 466 -0.30 ASN 632

LEU 483 0.20 ARG 467 -0.27 ASN 632

PHE 590 0.26 TRP 468 -0.24 ASN 632

VAL 544 0.28 HIS 469 -0.33 ASN 632

LEU 597 0.19 THR 470 -0.45 ASN 632

PHE 590 0.20 ILE 471 -0.33 ASN 632

GLY 547 0.31 THR 472 -0.30 ASN 632

VAL 544 0.31 HIS 473 -0.42 ASN 632

LEU 597 0.22 ALA 474 -0.65 SER 566

LEU 540 0.29 MET 475 -0.67 ASN 632

LEU 540 0.25 GLN 476 -0.63 ASN 632

VAL 562 0.15 LEU 477 -0.75 ASN 632

LEU 540 0.18 ASP 478 -0.50 ASN 632

LEU 540 0.32 CYS 479 -0.43 ASN 632

LEU 540 0.30 LYS 480 -0.42 ASN 632

LEU 540 0.22 VAL 481 -0.37 THR 395

SER 564 0.25 GLN 482 -0.30 THR 395

SER 566 0.33 LEU 483 -0.21 LYS 393

SER 566 0.25 ARG 484 -0.17 ALA 440

SER 566 0.15 HIS 485 -0.19 ASN 632

SER 566 0.17 ALA 486 -0.20 ASN 632

SER 566 0.19 ALA 487 -0.19 LEU 483

SER 566 0.13 SER 488 -0.15 ALA 499

LYS 480 0.10 VAL 489 -0.17 ASN 632

SER 566 0.11 MET 490 -0.16 LEU 477

SER 566 0.10 VAL 491 -0.19 PHE 498

LYS 480 0.10 MET 492 -0.15 VAL 544

LYS 480 0.10 GLY 493 -0.15 VAL 544

ILE 381 0.07 TRP 494 -0.18 PHE 498

ILE 381 0.07 ILE 495 -0.21 ALA 499

LYS 480 0.11 PHE 496 -0.18 HIS 430

LYS 480 0.08 ALA 497 -0.18 HIS 430

LEU 641 0.06 PHE 498 -0.19 VAL 491

LYS 480 0.06 ALA 499 -0.21 ILE 495

LYS 480 0.10 ALA 500 -0.23 HIS 430

LEU 641 0.08 ALA 501 -0.22 HIS 430

LEU 641 0.07 LEU 502 -0.20 HIS 430

LYS 480 0.07 PHE 503 -0.24 HIS 430

ILE 588 0.09 PRO 504 -0.28 HIS 430

ALA 444 0.10 ILE 505 -0.22 HIS 430

ALA 440 0.09 PHE 506 -0.21 HIS 430

ALA 440 0.12 GLY 507 -0.26 HIS 430

ALA 440 0.08 ILE 508 -0.28 HIS 430

ILE 588 0.11 SER 509 -0.35 HIS 430

ILE 588 0.11 SER 510 -0.37 HIS 430

ILE 588 0.11 TYR 511 -0.37 HIS 430

TYR 362 0.17 MET 512 -0.43 HIS 430

ILE 588 0.16 LYS 513 -0.59 HIS 430

VAL 612 0.17 VAL 514 -0.59 HIS 430

TYR 362 0.23 SER 515 -0.63 TYR 429

VAL 612 0.20 ILE 516 -0.41 TYR 429

LEU 641 0.14 CYS 517 -0.35 HIS 430

LEU 641 0.14 LEU 518 -0.36 HIS 430

ILE 588 0.14 PRO 519 -0.38 HIS 430

ILE 588 0.21 MET 520 -0.46 HIS 430

ILE 588 0.16 ASP 521 -0.47 HIS 430

ALA 592 0.17 ILE 522 -0.43 HIS 430

ALA 592 0.14 ASP 523 -0.43 HIS 430

MET 475 0.13 SER 524 -0.35 HIS 430

MET 475 0.16 PRO 525 -0.32 HIS 430

MET 475 0.13 LEU 526 -0.29 HIS 430

MET 475 0.13 SER 527 -0.33 HIS 430

MET 475 0.17 GLN 528 -0.36 HIS 430

MET 475 0.19 LEU 529 -0.31 HIS 430

LYS 480 0.16 TYR 530 -0.29 HIS 430

LYS 480 0.18 VAL 531 -0.33 HIS 430

CYS 479 0.23 MET 532 -0.33 SER 427

LYS 480 0.24 SER 533 -0.27 HIS 430

LYS 480 0.21 LEU 534 -0.26 HIS 430

CYS 479 0.23 LEU 535 -0.29 SER 427

CYS 479 0.28 VAL 536 -0.27 SER 427

LYS 480 0.29 LEU 537 -0.23 SER 427

CYS 479 0.24 ASN 538 -0.22 SER 427

CYS 479 0.26 VAL 539 -0.23 SER 427

CYS 479 0.32 LEU 540 -0.20 SER 427

CYS 479 0.28 ALA 541 -0.17 SER 427

PHE 590 0.31 PHE 542 -0.16 SER 427

PHE 590 0.34 VAL 543 -0.16 SER 427

HIS 473 0.31 VAL 544 -0.15 GLY 493

PHE 590 0.28 ILE 545 -0.13 THR 461

PHE 590 0.33 CYS 546 -0.10 SER 427

THR 472 0.31 GLY 547 -0.14 MET 492

THR 472 0.29 CYS 548 -0.15 MET 492

PHE 590 0.26 TYR 549 -0.09 MET 492

PHE 590 0.28 ILE 550 -0.10 MET 492

PHE 590 0.25 HIS 551 -0.17 LEU 465

PHE 590 0.22 ILE 552 -0.10 ASN 632

LEU 601 0.21 TYR 553 -0.07 ALA 474

LEU 601 0.23 LEU 554 -0.09 MET 492

LEU 601 0.21 THR 555 -0.15 THR 472

LYS 393 0.22 VAL 556 -0.18 THR 472

LYS 572 0.27 ARG 557 -0.15 THR 472

LYS 572 0.21 ASN 558 -0.23 THR 472

TYR 392 0.24 PRO 559 -0.21 THR 472

LEU 601 0.18 ASN 560 -0.26 THR 472

LEU 601 0.18 ILE 561 -0.30 THR 472

LYS 393 0.26 VAL 562 -0.25 MET 475

LYS 393 0.30 SER 563 -0.32 MET 475

LYS 393 0.40 SER 564 -0.56 ALA 474

LYS 393 0.47 SER 565 -0.50 ALA 474

LYS 393 0.51 SER 566 -0.65 ALA 474

THR 395 0.41 ASP 567 -0.60 ALA 474

LYS 393 0.36 THR 568 -0.38 ALA 474

LYS 393 0.38 ARG 569 -0.45 ALA 474

THR 395 0.39 ILE 570 -0.44 ALA 474

THR 395 0.27 ALA 571 -0.29 ALA 474

ARG 557 0.27 LYS 572 -0.24 ALA 474

LYS 393 0.24 ARG 573 -0.30 LEU 477

THR 395 0.22 MET 574 -0.21 LEU 477

LYS 393 0.19 ALA 575 -0.14 LEU 477

ARG 557 0.18 MET 576 -0.18 LEU 477

PHE 590 0.15 LEU 577 -0.19 LEU 477

PHE 590 0.20 ILE 578 -0.11 LEU 477

ILE 550 0.21 PHE 579 -0.10 SER 427

ILE 550 0.16 THR 580 -0.12 LEU 477

PHE 590 0.17 ASP 581 -0.13 SER 427

PHE 590 0.21 PHE 582 -0.16 SER 427

ILE 602 0.20 LEU 583 -0.16 SER 427

ALA 607 0.15 CYS 584 -0.18 SER 427

MET 520 0.17 MET 585 -0.21 SER 427

CYS 546 0.25 ALA 586 -0.24 SER 427

ILE 602 0.26 PRO 587 -0.29 SER 427

MET 520 0.21 ILE 588 -0.32 SER 427

THR 472 0.21 SER 589 -0.31 SER 427

VAL 543 0.34 PHE 590 -0.38 SER 427

CYS 546 0.26 PHE 591 -0.46 SER 427

THR 472 0.20 ALA 592 -0.43 SER 427

VAL 543 0.29 ILE 593 -0.41 SER 427

VAL 543 0.30 SER 594 -0.49 SER 427

THR 472 0.22 ALA 595 -0.55 SER 427

HIS 473 0.23 SER 596 -0.49 SER 427

HIS 473 0.29 LEU 597 -0.50 SER 427

HIS 473 0.26 LYS 598 -0.59 SER 427

THR 472 0.27 VAL 599 -0.60 SER 427

THR 472 0.24 PRO 600 -0.64 SER 427

ILE 550 0.27 LEU 601 -0.60 SER 427

PRO 587 0.26 ILE 602 -0.65 SER 427

PRO 587 0.21 THR 603 -0.79 SER 427

PRO 587 0.20 VAL 604 -0.79 SER 427

ILE 550 0.18 SER 605 -0.87 SER 427

PRO 587 0.21 LYS 606 -0.68 SER 427

PRO 587 0.22 ALA 607 -0.57 SER 427

SER 642 0.15 LYS 608 -0.53 SER 427

SER 642 0.18 ILE 609 -0.44 SER 427

LEU 641 0.17 LEU 610 -0.38 SER 427

VAL 514 0.16 LEU 611 -0.32 SER 427

SER 515 0.21 VAL 612 -0.24 SER 427

LEU 641 0.21 LEU 613 -0.20 SER 427

LEU 641 0.18 PHE 614 -0.20 SER 427

LEU 641 0.17 HIS 615 -0.19 SER 427

LEU 641 0.19 PRO 616 -0.14 LEU 477

LEU 641 0.21 ILE 617 -0.13 LEU 477

LEU 641 0.17 ASN 618 -0.14 LEU 477

LEU 641 0.18 SER 619 -0.18 LEU 477

LEU 641 0.23 CYS 620 -0.20 LEU 477

LEU 641 0.19 ALA 621 -0.22 LEU 477

LEU 641 0.15 ASN 622 -0.25 LEU 477

LEU 641 0.18 PRO 623 -0.31 LEU 477

PHE 371 0.20 PHE 624 -0.33 LEU 477

TYR 392 0.15 LEU 625 -0.31 LEU 477

TYR 392 0.17 TYR 626 -0.38 LEU 477

SER 390 0.19 ALA 627 -0.46 LEU 477

PHE 371 0.20 ILE 628 -0.43 LEU 477

PHE 371 0.18 PHE 629 -0.44 LEU 477

GLN 391 0.21 THR 630 -0.56 LEU 477

GLN 391 0.19 LYS 631 -0.62 LEU 477

GLN 391 0.27 ASN 632 -0.75 LEU 477

GLN 391 0.21 PHE 633 -0.60 LEU 477

PHE 371 0.24 ARG 634 -0.56 LEU 477

PHE 371 0.22 ARG 635 -0.64 LEU 477

LEU 375 0.20 ASP 636 -0.59 LEU 477

LEU 375 0.28 PHE 637 -0.48 LEU 477

LEU 375 0.33 PHE 638 -0.52 MET 475

PHE 371 0.26 ILE 639 -0.55 MET 475

LEU 375 0.27 LEU 640 -0.45 LEU 477

LEU 375 0.39 LEU 641 -0.42 MET 475

PHE 371 0.36 SER 642 -0.49 MET 475

THR 378 0.30 LYS 643 -0.43 MET 475

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** HORMONE 14-JAN-23 8I2H ***

CA distance fluctuations for 2603021201203093406

--- normal mode 11 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* HORMONE 14-JAN-23 8I2H *