Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* HORMONE 14-JAN-23 8I2H *

CA distance fluctuations for 2603111922412150910

--- normal mode 10 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
SER 515 0.41 TYR 362 -0.47 SER 427

SER 515 0.31 ASN 363 -0.42 SER 642

SER 515 0.25 ILE 364 -0.44 SER 642

SER 515 0.25 LEU 365 -0.39 SER 642

SER 515 0.21 ARG 366 -0.40 SER 642

SER 515 0.15 VAL 367 -0.47 SER 642

SER 515 0.13 LEU 368 -0.46 LEU 641

ILE 516 0.12 ILE 369 -0.42 LEU 641

LEU 415 0.07 TRP 370 -0.46 LEU 641

LEU 613 0.08 PHE 371 -0.53 LEU 641

PHE 371 0.07 ILE 372 -0.45 LEU 641

HIS 615 0.06 SER 373 -0.43 LEU 641

ILE 617 0.06 ILE 374 -0.52 LEU 641

ILE 617 0.10 LEU 375 -0.54 LEU 641

SER 619 0.09 ALA 376 -0.40 LEU 641

SER 619 0.07 ILE 377 -0.42 LEU 641

ALA 621 0.10 THR 378 -0.54 LEU 641

ALA 621 0.11 GLY 379 -0.42 LEU 641

ALA 621 0.06 ASN 380 -0.31 LEU 641

PHE 624 0.09 ILE 381 -0.35 LEU 641

PHE 624 0.11 ILE 382 -0.38 LEU 641

PHE 624 0.08 VAL 383 -0.30 SER 566

ILE 628 0.07 LEU 384 -0.33 SER 566

ILE 628 0.07 VAL 385 -0.32 SER 566

LEU 477 0.06 ILE 386 -0.37 SER 566

ARG 635 0.12 LEU 387 -0.48 SER 566

PHE 406 0.10 THR 388 -0.47 SER 566

ILE 495 0.07 THR 389 -0.44 SER 566

ILE 639 0.15 SER 390 -0.55 SER 566

LYS 643 0.16 GLN 391 -0.61 SER 566

ILE 639 0.32 TYR 392 -0.77 SER 566

ILE 639 0.23 LYS 393 -0.82 SER 566

ARG 635 0.23 LEU 394 -0.71 SER 566

ASN 632 0.34 THR 395 -0.74 SER 566

ASN 632 0.42 VAL 396 -0.45 SER 564

ASN 632 0.51 PRO 397 -0.48 ASP 567

ASN 632 0.40 ARG 398 -0.56 SER 566

ASN 632 0.28 PHE 399 -0.42 SER 566

ASN 632 0.31 LEU 400 -0.31 SER 566

ASN 632 0.26 MET 401 -0.35 SER 566

ASN 632 0.20 CYS 402 -0.34 SER 566

ASN 632 0.19 ASN 403 -0.27 SER 566

ASN 632 0.16 LEU 404 -0.23 SER 566

ASN 632 0.09 ALA 405 -0.25 SER 566

THR 388 0.10 PHE 406 -0.23 SER 566

ASN 632 0.09 ALA 407 -0.19 SER 566

ASP 581 0.06 ASP 408 -0.22 LEU 641

HIS 424 0.06 LEU 409 -0.28 LEU 641

HIS 424 0.09 CYS 410 -0.25 LEU 641

MET 585 0.08 ILE 411 -0.26 LEU 641

MET 585 0.07 GLY 412 -0.33 LEU 641

HIS 424 0.10 ILE 413 -0.33 LEU 641

TYR 362 0.12 TYR 414 -0.30 LEU 641

TYR 362 0.10 LEU 415 -0.33 LEU 641

ILE 413 0.06 LEU 416 -0.38 LEU 641

SER 420 0.12 LEU 417 -0.32 LEU 641

TYR 362 0.15 ILE 418 -0.32 LEU 641

ARG 366 0.10 ALA 419 -0.36 LEU 641

LEU 417 0.12 SER 420 -0.34 SER 642

ALA 444 0.14 VAL 421 -0.34 SER 605

CYS 442 0.10 ASP 422 -0.49 SER 605

ALA 444 0.10 ILE 423 -0.43 SER 605

ALA 444 0.14 HIS 424 -0.44 SER 605

GLY 441 0.11 THR 425 -0.58 SER 605

GLY 441 0.08 LYS 426 -0.71 SER 605

HIS 424 0.07 SER 427 -0.88 SER 605

GLY 441 0.09 GLN 428 -0.74 SER 605

ASN 363 0.08 TYR 429 -0.75 SER 605

ASN 363 0.08 HIS 430 -0.81 VAL 604

ALA 440 0.13 ASN 431 -0.59 VAL 604

ALA 440 0.16 TYR 432 -0.42 SER 605

ASN 363 0.22 ALA 433 -0.44 VAL 604

TYR 362 0.21 ILE 434 -0.33 LYS 598

GLY 439 0.16 ASP 435 -0.25 LYS 598

TYR 362 0.19 TRP 436 -0.25 SER 642

TYR 362 0.28 GLN 437 -0.25 LYS 598

TYR 362 0.22 THR 438 -0.22 LEU 641

ILE 505 0.21 GLY 439 -0.25 LEU 641

ILE 505 0.19 ALA 440 -0.24 LEU 641

TYR 432 0.16 GLY 441 -0.26 LEU 641

TYR 362 0.25 CYS 442 -0.24 LEU 641

TYR 362 0.21 ASP 443 -0.22 LEU 641

TYR 362 0.18 ALA 444 -0.23 LEU 641

TYR 362 0.20 ALA 445 -0.25 LEU 641

TYR 362 0.21 GLY 446 -0.22 LEU 641

TYR 362 0.17 PHE 447 -0.20 LEU 641

TYR 362 0.14 PHE 448 -0.21 LEU 641

TYR 362 0.14 THR 449 -0.22 LEU 641

TYR 362 0.13 VAL 450 -0.18 HIS 430

TYR 362 0.11 PHE 451 -0.16 LEU 641

TYR 362 0.08 ALA 452 -0.18 LEU 641

MET 585 0.09 SER 453 -0.18 HIS 430

ASN 538 0.12 GLU 454 -0.16 HIS 430

ASN 632 0.14 LEU 455 -0.15 SER 566

ASN 632 0.14 SER 456 -0.15 HIS 430

ASN 632 0.15 VAL 457 -0.17 HIS 430

ASN 632 0.19 TYR 458 -0.13 HIS 430

ASN 632 0.22 THR 459 -0.16 VAL 562

ASN 632 0.22 LEU 460 -0.15 HIS 430

ASN 632 0.23 THR 461 -0.15 HIS 430

ASN 632 0.28 ALA 462 -0.17 VAL 562

ASN 632 0.32 ILE 463 -0.19 VAL 562

ASN 632 0.25 THR 464 -0.14 HIS 430

ASN 632 0.28 LEU 465 -0.14 VAL 562

ASN 632 0.36 GLU 466 -0.23 VAL 562

ASN 632 0.30 ARG 467 -0.24 THR 395

ASN 632 0.24 TRP 468 -0.17 THR 395

ASN 632 0.29 HIS 469 -0.21 VAL 562

ASN 632 0.33 THR 470 -0.32 VAL 562

ASN 632 0.22 ILE 471 -0.30 THR 395

ASN 632 0.20 THR 472 -0.18 THR 395

ASN 632 0.28 HIS 473 -0.23 VAL 562

SER 566 0.36 ALA 474 -0.38 VAL 562

ASN 632 0.36 MET 475 -0.31 VAL 562

ASN 632 0.40 GLN 476 -0.35 VAL 562

ASN 632 0.48 LEU 477 -0.47 VAL 562

ASN 632 0.42 ASP 478 -0.37 VAL 562

ASN 632 0.35 CYS 479 -0.26 VAL 562

ASN 632 0.38 LYS 480 -0.29 VAL 562

ASN 632 0.39 VAL 481 -0.33 VAL 562

ASN 632 0.35 GLN 482 -0.43 VAL 562

ASN 632 0.29 LEU 483 -0.44 VAL 562

ASN 632 0.23 ARG 484 -0.36 VAL 562

ASN 632 0.28 HIS 485 -0.29 VAL 562

ASN 632 0.29 ALA 486 -0.32 VAL 562

ASN 632 0.25 ALA 487 -0.30 VAL 562

ASN 632 0.22 SER 488 -0.27 VAL 562

ASN 632 0.22 VAL 489 -0.25 VAL 562

ASN 632 0.21 MET 490 -0.25 VAL 562

ASN 632 0.19 VAL 491 -0.23 VAL 562

ASN 632 0.18 MET 492 -0.21 VAL 562

ASN 632 0.18 GLY 493 -0.18 VAL 562

ASN 632 0.16 TRP 494 -0.18 VAL 562

ASN 632 0.15 ILE 495 -0.17 VAL 562

ASN 632 0.14 PHE 496 -0.14 VAL 562

ASN 632 0.12 ALA 497 -0.12 SER 566

ALA 440 0.12 PHE 498 -0.13 VAL 562

ALA 440 0.13 ALA 499 -0.11 VAL 562

TYR 362 0.12 ALA 500 -0.13 HIS 430

TYR 362 0.14 ALA 501 -0.15 LEU 641

ALA 440 0.17 LEU 502 -0.15 LEU 641

TYR 362 0.15 PHE 503 -0.14 LEU 641

TYR 362 0.18 PRO 504 -0.16 LEU 641

GLY 439 0.21 ILE 505 -0.17 LEU 641

GLY 439 0.19 PHE 506 -0.14 LEU 641

TYR 362 0.18 GLY 507 -0.15 LEU 641

TYR 362 0.17 ILE 508 -0.15 HIS 430

TYR 362 0.19 SER 509 -0.21 HIS 430

TYR 362 0.23 SER 510 -0.21 HIS 430

TYR 362 0.25 TYR 511 -0.24 HIS 430

TYR 362 0.29 MET 512 -0.26 HIS 430

TYR 362 0.30 LYS 513 -0.40 HIS 430

TYR 362 0.35 VAL 514 -0.50 HIS 430

TYR 362 0.41 SER 515 -0.50 HIS 430

TYR 362 0.35 ILE 516 -0.38 HIS 430

TYR 362 0.29 CYS 517 -0.28 HIS 430

TYR 362 0.24 LEU 518 -0.33 HIS 430

TYR 362 0.21 PRO 519 -0.30 HIS 430

TYR 362 0.23 MET 520 -0.39 HIS 430

TYR 362 0.22 ASP 521 -0.34 HIS 430

TYR 362 0.19 ILE 522 -0.33 HIS 430

TYR 362 0.20 ASP 523 -0.31 HIS 430

TYR 362 0.18 SER 524 -0.23 HIS 430

TYR 362 0.14 PRO 525 -0.23 HIS 430

TYR 362 0.14 LEU 526 -0.19 HIS 430

TYR 362 0.16 SER 527 -0.23 HIS 430

ASN 558 0.14 GLN 528 -0.29 HIS 430

ASN 558 0.14 LEU 529 -0.24 HIS 430

TYR 362 0.11 TYR 530 -0.22 HIS 430

ASN 558 0.13 VAL 531 -0.28 HIS 430

ASN 558 0.16 MET 532 -0.29 HIS 430

VAL 489 0.15 SER 533 -0.23 HIS 430

VAL 489 0.13 LEU 534 -0.23 HIS 430

GLY 547 0.16 LEU 535 -0.28 HIS 430

LEU 597 0.19 VAL 536 -0.25 HIS 430

VAL 489 0.19 LEU 537 -0.21 HIS 430

VAL 489 0.15 ASN 538 -0.21 HIS 430

ILE 593 0.23 VAL 539 -0.22 HIS 430

LEU 597 0.21 LEU 540 -0.20 HIS 430

HIS 485 0.18 ALA 541 -0.18 HIS 430

PHE 590 0.24 PHE 542 -0.18 HIS 430

PHE 590 0.29 VAL 543 -0.17 HIS 430

LEU 597 0.22 VAL 544 -0.15 HIS 430

PHE 590 0.20 ILE 545 -0.15 HIS 430

PHE 590 0.28 CYS 546 -0.15 SER 427

PHE 590 0.28 GLY 547 -0.13 SER 427

PHE 590 0.22 CYS 548 -0.13 HIS 430

PHE 590 0.22 TYR 549 -0.17 LYS 393

PHE 590 0.28 ILE 550 -0.19 LYS 393

LEU 597 0.25 HIS 551 -0.20 LYS 393

PHE 590 0.21 ILE 552 -0.27 THR 395

PHE 590 0.23 TYR 553 -0.29 LYS 393

SER 594 0.28 LEU 554 -0.29 LYS 393

VAL 599 0.23 THR 555 -0.33 LYS 393

VAL 599 0.20 VAL 556 -0.44 LYS 393

VAL 599 0.24 ARG 557 -0.42 LYS 393

VAL 599 0.28 ASN 558 -0.41 LYS 393

VAL 599 0.27 PRO 559 -0.51 LYS 393

VAL 599 0.26 ASN 560 -0.44 LYS 393

VAL 599 0.20 ILE 561 -0.49 LYS 393

ARG 557 0.22 VAL 562 -0.64 LYS 393

VAL 599 0.15 SER 563 -0.64 LYS 393

MET 475 0.16 SER 564 -0.79 LYS 393

MET 475 0.20 SER 565 -0.74 LYS 393

ALA 474 0.36 SER 566 -0.82 LYS 393

ALA 474 0.33 ASP 567 -0.69 THR 395

PHE 590 0.14 THR 568 -0.54 LYS 393

ALA 474 0.23 ARG 569 -0.50 LYS 393

ALA 474 0.25 ILE 570 -0.49 THR 395

ALA 474 0.15 ALA 571 -0.37 THR 395

MET 576 0.13 LYS 572 -0.33 LYS 393

LEU 477 0.18 ARG 573 -0.27 TYR 392

ARG 573 0.18 MET 574 -0.22 THR 395

PHE 590 0.15 ALA 575 -0.22 LYS 393

LYS 572 0.13 MET 576 -0.19 TYR 392

LEU 477 0.09 LEU 577 -0.17 SER 427

PHE 590 0.14 ILE 578 -0.17 SER 427

PHE 590 0.13 PHE 579 -0.20 SER 427

LEU 477 0.07 THR 580 -0.21 SER 427

PHE 590 0.08 ASP 581 -0.20 HIS 430

PHE 590 0.16 PHE 582 -0.22 SER 427

ASN 558 0.12 LEU 583 -0.25 SER 427

ASN 558 0.09 CYS 584 -0.26 SER 427

ASN 558 0.12 MET 585 -0.25 HIS 430

LEU 554 0.19 ALA 586 -0.27 SER 427

ASN 558 0.18 PRO 587 -0.33 SER 427

LEU 554 0.15 ILE 588 -0.35 HIS 430

ILE 550 0.19 SER 589 -0.32 HIS 430

VAL 543 0.29 PHE 590 -0.39 HIS 430

LEU 554 0.22 PHE 591 -0.46 HIS 430

LEU 554 0.19 ALA 592 -0.44 HIS 430

VAL 543 0.27 ILE 593 -0.41 HIS 430

ASN 558 0.28 SER 594 -0.49 HIS 430

ASN 558 0.22 ALA 595 -0.57 HIS 430

ASN 558 0.21 SER 596 -0.48 HIS 430

ASN 558 0.28 LEU 597 -0.50 HIS 430

ASN 558 0.26 LYS 598 -0.61 HIS 430

ASN 558 0.28 VAL 599 -0.61 HIS 430

ASN 558 0.24 PRO 600 -0.65 HIS 430

ASN 558 0.26 LEU 601 -0.58 HIS 430

ASN 558 0.21 ILE 602 -0.62 SER 427

ASN 558 0.18 THR 603 -0.74 SER 427

ASP 523 0.18 VAL 604 -0.81 HIS 430

ASP 523 0.15 SER 605 -0.88 SER 427

ASN 558 0.14 LYS 606 -0.71 SER 427

LEU 554 0.14 ALA 607 -0.58 SER 427

TYR 362 0.18 LYS 608 -0.55 SER 427

MET 520 0.09 ILE 609 -0.55 SER 427

ASN 558 0.10 LEU 610 -0.45 SER 427

LEU 554 0.08 LEU 611 -0.37 SER 427

GLY 446 0.08 VAL 612 -0.35 SER 427

PHE 371 0.08 LEU 613 -0.31 SER 427

ASN 558 0.06 PHE 614 -0.30 SER 427

PHE 371 0.07 HIS 615 -0.26 HIS 430

LEU 375 0.08 PRO 616 -0.26 LEU 641

LEU 375 0.10 ILE 617 -0.26 LEU 641

THR 378 0.07 ASN 618 -0.21 HIS 430

ALA 376 0.09 SER 619 -0.21 LEU 641

THR 378 0.09 CYS 620 -0.28 LEU 641

GLY 379 0.11 ALA 621 -0.25 ILE 617

LEU 477 0.07 ASN 622 -0.19 LEU 368

LEU 477 0.08 PRO 623 -0.23 LEU 368

LEU 477 0.14 PHE 624 -0.34 LEU 368

LEU 477 0.15 LEU 625 -0.25 LEU 368

LEU 477 0.16 TYR 626 -0.22 SER 566

LEU 477 0.19 ALA 627 -0.27 SER 566

LEU 477 0.21 ILE 628 -0.35 LEU 368

LEU 477 0.26 PHE 629 -0.32 LEU 368

LEU 477 0.36 THR 630 -0.28 LEU 368

LEU 477 0.43 LYS 631 -0.30 ILE 364

PRO 397 0.51 ASN 632 -0.30 GLN 391

PRO 397 0.38 PHE 633 -0.28 LEU 368

LEU 477 0.33 ARG 634 -0.38 LEU 368

LEU 477 0.40 ARG 635 -0.34 PHE 371

LEU 477 0.28 ASP 636 -0.31 LEU 375

LEU 477 0.21 PHE 637 -0.43 LEU 375

LEU 477 0.29 PHE 638 -0.48 PHE 371

TYR 392 0.32 ILE 639 -0.39 PHE 371

TYR 392 0.21 LEU 640 -0.40 LEU 375

LEU 477 0.18 LEU 641 -0.54 LEU 375

TYR 392 0.25 SER 642 -0.51 PHE 371

TYR 392 0.22 LYS 643 -0.44 PHE 371

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** HORMONE 14-JAN-23 8I2H ***

CA distance fluctuations for 2603111922412150910

--- normal mode 10 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* HORMONE 14-JAN-23 8I2H *