Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* *

CA distance fluctuations for 260408115242648516

--- normal mode 11 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ARG 818 0.33 THR 69 -0.61 GLU 1265

ARG 818 0.28 ILE 70 -0.64 GLY 1264

ARG 818 0.25 ALA 71 -0.59 GLY 1264

GLU 1593 0.27 PHE 72 -0.57 SER 1261

GLU 1593 0.31 GLU 73 -0.50 SER 1261

GLU 1593 0.32 PHE 74 -0.44 SER 1261

GLU 1593 0.37 ASP 75 -0.40 ARG 1257

GLU 1593 0.38 GLY 76 -0.43 ARG 1257

GLU 1593 0.36 GLN 77 -0.43 ARG 1257

GLU 1593 0.32 GLN 78 -0.47 GLY 1264

GLU 1593 0.29 VAL 79 -0.48 GLY 1264

ARG 818 0.26 GLU 80 -0.52 GLY 1264

ARG 818 0.28 ALA 81 -0.51 GLU 1265

ARG 818 0.34 GLN 82 -0.52 GLU 1265

ARG 818 0.34 PRO 83 -0.58 GLU 1265

ARG 818 0.32 GLY 84 -0.54 PRO 1374

ARG 818 0.27 GLU 85 -0.49 PRO 1374

ARG 818 0.21 THR 86 -0.52 PRO 1374

GLU 1593 0.21 ILE 87 -0.47 PRO 1374

ARG 289 0.20 TRP 88 -0.37 PRO 1374

ARG 289 0.24 ALA 89 -0.37 PRO 1374

ARG 289 0.24 VAL 90 -0.39 PRO 1374

GLU 1593 0.26 ALA 91 -0.34 SER 1261

ARG 289 0.27 LYS 92 -0.30 PRO 1374

ARG 289 0.29 ARG 93 -0.33 SER 1261

ARG 289 0.27 LEU 94 -0.35 SER 1261

ASP 288 0.29 GLY 95 -0.30 SER 1261

GLU 1593 0.30 THR 96 -0.30 SER 1261

GLU 1593 0.26 HSD 97 -0.26 SER 1261

GLU 1593 0.25 ILE 98 -0.25 ARG 1257

GLN 180 0.21 PRO 99 -0.20 ARG 1257

GLU 1593 0.13 HSD 100 -0.18 GLN 490

HSD 100 0.13 LEU 101 -0.16 GLN 490

ARG 1153 0.09 CYS 102 -0.18 GLN 490

GLU 290 0.11 HSD 103 -0.22 GLN 490

GLU 290 0.13 LYS 104 -0.21 GLN 490

GLY 84 0.17 PRO 105 -0.23 GLN 490

LYS 292 0.15 ASP 106 -0.24 LEU 461

ASN 320 0.18 PRO 107 -0.31 LEU 461

TYR 109 0.13 GLY 108 -0.35 ASN 486

GLY 108 0.13 TYR 109 -0.29 GLN 490

GLY 108 0.12 ARG 110 -0.35 GLN 490

LYS 292 0.10 PRO 111 -0.27 GLN 490

LYS 292 0.08 ASP 112 -0.22 GLN 490

GLU 290 0.08 GLY 113 -0.19 GLN 490

GLU 290 0.07 ASN 114 -0.14 GLN 490

ARG 1153 0.08 CYS 115 -0.15 PHE 1253

GLU 1593 0.11 ARG 116 -0.20 PHE 1253

GLU 1593 0.15 ALA 117 -0.20 PHE 1253

GLU 1593 0.19 CYS 118 -0.24 PHE 1253

GLU 1593 0.22 MET 119 -0.29 PHE 1253

GLU 1593 0.26 VAL 120 -0.34 PHE 1253

GLU 1593 0.29 GLU 121 -0.40 PHE 1253

GLU 1593 0.27 ILE 122 -0.47 PHE 1253

GLU 1593 0.29 GLU 123 -0.53 ARG 1257

GLU 1593 0.26 GLY 124 -0.63 PHE 1253

GLU 1593 0.23 GLU 125 -0.61 PHE 1253

GLU 1593 0.22 ARG 126 -0.57 PHE 1253

GLU 1593 0.21 VAL 127 -0.45 ALA 1251

GLU 1593 0.22 LEU 128 -0.38 PHE 1253

GLU 1593 0.19 ALA 129 -0.36 PHE 1253

GLU 1593 0.16 ALA 130 -0.31 PRO 1374

GLU 1593 0.18 SER 131 -0.36 PRO 1374

GLU 290 0.15 CYS 132 -0.34 PRO 1374

ARG 818 0.12 LYS 133 -0.38 PRO 1374

GLU 1593 0.15 ARG 134 -0.59 PRO 1374

ARG 818 0.20 THR 135 -0.68 PRO 1374

GLU 1593 0.21 PRO 136 -0.59 PRO 1374

ARG 818 0.23 ALA 137 -0.69 SER 1261

ARG 818 0.24 ILE 138 -0.71 SER 1261

GLU 1593 0.25 GLY 139 -0.67 SER 1261

GLU 1593 0.26 MET 140 -0.60 SER 1261

GLU 1593 0.29 LYS 141 -0.52 ARG 1257

GLU 1593 0.29 VAL 142 -0.45 ARG 1257

GLU 1593 0.34 LYS 143 -0.39 ARG 1257

GLU 1593 0.34 SER 144 -0.33 ARG 1257

GLU 1593 0.41 ALA 145 -0.31 ARG 1257

GLU 1593 0.43 THR 146 -0.32 GLY 1484

GLU 1593 0.47 GLU 147 -0.31 GLY 1484

GLU 1593 0.38 ARG 148 -0.33 GLY 1484

GLU 1593 0.32 ALA 149 -0.29 PHE 1253

GLU 1593 0.35 THR 150 -0.26 GLY 1484

ALA 1592 0.36 LYS 151 -0.26 LYS 1488

ALA 1592 0.26 ALA 152 -0.25 GLY 1484

GLU 1593 0.24 ARG 153 -0.22 PHE 1253

GLU 1593 0.26 ALA 154 -0.21 LYS 1488

ALA 1592 0.21 MET 155 -0.21 LYS 1488

ALA 1592 0.13 VAL 156 -0.18 GLY 1484

PRO 99 0.13 LEU 157 -0.17 GLU 1487

ARG 1153 0.15 GLU 158 -0.18 LYS 1488

GLU 1149 0.15 LEU 159 -0.17 GLY 1490

ARG 1153 0.15 LEU 160 -0.14 GLY 1490

ARG 1153 0.17 VAL 161 -0.14 LYS 1488

ARG 1153 0.19 ALA 162 -0.15 GLY 1490

ARG 1153 0.20 ASP 163 -0.15 GLU 1593

ARG 1153 0.19 GLN 164 -0.14 PRO 165

SER 1157 0.20 PRO 165 -0.21 GLU 1593

SER 1157 0.20 GLU 166 -0.21 GLU 1593

SER 1157 0.17 ARG 167 -0.13 LYS 1488

SER 1157 0.18 ALA 168 -0.14 GLU 1593

SER 1157 0.19 THR 169 -0.21 GLU 1593

SER 1157 0.18 SER 170 -0.17 GLU 1593

ASP 1158 0.17 HSD 171 -0.15 GLU 1593

ASP 1158 0.15 ASP 172 -0.10 LEU 461

SER 1157 0.16 PRO 173 -0.12 ASN 320

GLY 95 0.16 SER 174 -0.15 ASN 320

HSD 97 0.15 SER 175 -0.15 PRO 267

HSD 97 0.17 HSD 176 -0.16 GLN 490

PRO 99 0.14 PHE 177 -0.15 GLN 490

HSD 97 0.16 TRP 178 -0.13 GLN 490

HSD 97 0.22 VAL 179 -0.15 LEU 461

HSD 97 0.22 GLN 180 -0.15 GLN 490

HSD 97 0.15 ALA 181 -0.15 GLY 1484

GLU 1593 0.18 ASP 182 -0.15 GLY 1484

GLU 1593 0.23 VAL 183 -0.17 ARG 1257

GLU 1593 0.27 LEU 184 -0.18 GLY 1484

GLU 1593 0.29 ASP 185 -0.18 LYS 1488

GLU 1593 0.21 VAL 186 -0.18 LYS 1488

ARG 1153 0.17 THR 187 -0.17 LYS 1488

ARG 1153 0.19 GLU 188 -0.18 LYS 1488

ARG 1153 0.17 SER 189 -0.16 GLY 1490

GLU 1149 0.18 ARG 190 -0.17 GLY 1490

GLU 1149 0.19 PHE 191 -0.16 GLY 1490

GLU 1149 0.22 PRO 192 -0.24 ALA 1592

ARG 1153 0.23 ALA 193 -0.24 GLU 1593

GLN 1152 0.24 ALA 194 -0.26 GLU 1593

GLN 1152 0.26 GLU 195 -0.29 GLU 1593

SER 1157 0.23 ARG 196 -0.23 GLU 1593

ASP 1158 0.22 TRP 197 -0.24 GLU 1593

ASP 1158 0.23 THR 198 -0.26 GLU 1593

ASP 1158 0.20 SER 199 -0.23 GLU 1593

ASP 1158 0.18 ASP 200 -0.21 GLU 1593

ASP 1158 0.17 VAL 201 -0.20 GLU 1593

ASP 1158 0.16 SER 202 -0.19 GLU 1593

ASP 1158 0.14 HSD 203 -0.16 GLU 1593

ASP 1158 0.13 PRO 204 -0.16 GLU 1593

ASP 1158 0.12 ALA 205 -0.13 GLU 1593

ASP 1158 0.13 MET 206 -0.13 GLU 1593

ASP 1158 0.15 SER 207 -0.16 GLU 1593

ASP 1158 0.16 VAL 208 -0.16 GLU 1593

ASP 1158 0.18 ASN 209 -0.19 GLU 1593

ASP 1158 0.18 LEU 210 -0.17 GLU 1593

ASP 1158 0.19 ASP 211 -0.20 GLU 1593

SER 1157 0.17 ALA 212 -0.14 GLU 1593

ASP 1158 0.15 CYS 213 -0.13 ASN 1542

SER 1157 0.13 ILE 214 -0.11 ASN 1542

SER 1157 0.11 GLN 215 -0.10 ASN 1542

SER 1157 0.09 CYS 216 -0.13 GLN 490

SER 1157 0.08 ASN 217 -0.13 GLN 490

ASP 1158 0.08 LEU 218 -0.15 GLN 490

ASP 1158 0.09 CYS 219 -0.12 ALA 222

THR 1111 0.08 VAL 220 -0.12 ALA 509

LYS 1365 0.07 ARG 221 -0.13 LYS 489

GLY 318 0.07 ALA 222 -0.12 CYS 219

ALA 1332 0.08 CYS 223 -0.09 ALA 509

LYS 1365 0.09 ARG 224 -0.14 ALA 509

LYS 1365 0.07 GLU 225 -0.19 LYS 489

ASN 326 0.08 VAL 226 -0.18 ASN 486

ASN 324 0.07 GLN 227 -0.12 THR 482

ALA 1332 0.08 VAL 228 -0.15 LEU 505

ALA 1332 0.09 ASN 229 -0.11 THR 504

ALA 1332 0.09 ASP 230 -0.12 GLY 84

ALA 1104 0.10 VAL 231 -0.10 GLU 1593

ILE 1126 0.09 ILE 232 -0.10 ASN 1542

THR 1111 0.10 GLY 233 -0.11 GLY 84

THR 1111 0.11 MET 234 -0.10 GLY 84

THR 1111 0.19 ALA 235 -0.11 GLY 84

THR 1111 0.13 TYR 236 -0.11 GLU 1593

ALA 1347 0.11 ARG 237 -0.10 GLY 84

VAL 1163 0.11 ALA 238 -0.11 SER 1522

VAL 1163 0.13 ALA 239 -0.15 GLN 1534

VAL 1163 0.15 GLY 240 -0.14 ASN 1542

VAL 1163 0.11 SER 241 -0.12 ASN 1542

ILE 1126 0.13 LYS 242 -0.13 GLU 1593

ILE 1126 0.12 VAL 243 -0.12 GLU 1593

ILE 1126 0.14 VAL 244 -0.13 GLU 1593

ILE 1126 0.11 PHE 245 -0.13 GLU 1593

ALA 1332 0.11 ASP 246 -0.13 GLU 1593

ILE 1126 0.13 PHE 247 -0.14 GLU 1593

ILE 1126 0.16 ASP 248 -0.16 GLU 1593

ILE 1126 0.15 ASP 249 -0.17 GLU 1593

ILE 1126 0.14 PRO 250 -0.17 GLU 1593

ASP 1158 0.12 MET 251 -0.15 GLU 1593

HSD 203 0.13 GLY 252 -0.16 GLU 1593

GLU 1121 0.12 GLY 253 -0.16 GLU 1593

ILE 1126 0.11 SER 254 -0.14 GLU 1593

ALA 1332 0.10 THR 255 -0.12 GLU 1593

ILE 1126 0.09 CYS 256 -0.12 GLU 1593

ALA 1332 0.09 VAL 257 -0.10 GLU 1593

ASP 1158 0.09 ALA 258 -0.10 GLU 1593

ASP 1158 0.08 CYS 259 -0.08 ASN 1542

ASP 1158 0.09 GLY 260 -0.09 ASN 1542

ASP 1158 0.09 GLU 261 -0.10 THR 482

ASP 1158 0.10 CYS 262 -0.09 ASN 486

ASP 1158 0.11 VAL 263 -0.09 ASN 1542

ASP 1158 0.10 GLN 264 -0.10 LEU 461

ASP 1158 0.10 ALA 265 -0.13 LEU 461

ASP 1158 0.11 CYS 266 -0.11 GLN 490

LYS 92 0.13 PRO 267 -0.15 SER 175

GLY 269 0.14 THR 268 -0.13 GLN 164

THR 268 0.14 GLY 269 -0.09 ASN 1542

ASP 1158 0.15 ALA 270 -0.12 GLU 1593

ASP 1158 0.14 LEU 271 -0.11 GLU 1593

ASP 1158 0.13 MET 272 -0.11 GLU 1593

ASP 1158 0.12 PRO 273 -0.12 GLU 1593

ASP 1158 0.13 ALA 274 -0.15 GLU 1593

GLY 890 0.14 ALA 275 -0.14 GLU 1593

GLY 95 0.15 TYR 276 -0.13 GLU 1593

ASP 1158 0.15 LEU 277 -0.18 GLU 1593

GLY 1038 0.16 ASP 278 -0.23 GLU 1593

GLY 1038 0.19 ALA 279 -0.27 GLU 1593

ASP 1158 0.18 ASN 280 -0.29 GLU 1593

ASP 1158 0.17 GLN 281 -0.23 GLU 1593

ASP 1158 0.16 THR 282 -0.21 GLU 1593

GLY 95 0.16 ARG 283 -0.16 GLU 1593

GLY 95 0.17 THR 284 -0.12 GLU 1593

GLY 95 0.20 VAL 285 -0.11 GLU 1593

GLY 95 0.25 TYR 286 -0.07 THR 169

GLY 95 0.25 PRO 287 -0.06 ASN 1542

GLY 95 0.29 ASP 288 -0.06 ARG 818

ARG 93 0.29 ARG 289 -0.06 ARG 818

ARG 93 0.28 GLU 290 -0.07 GLU 819

ARG 93 0.25 VAL 291 -0.07 GLY 820

GLN 82 0.24 LYS 292 -0.13 SER 293

GLN 82 0.19 SER 293 -0.13 LYS 292

PRO 83 0.14 LEU 294 -0.07 LYS 292

GLN 82 0.10 CYS 295 -0.06 ASN 1542

GLN 82 0.09 PRO 296 -0.06 ASN 1542

ASP 1158 0.07 TYR 297 -0.06 ASN 1542

ALA 1332 0.06 CYS 298 -0.06 ASN 1542

ALA 1332 0.06 GLY 299 -0.06 ASN 1542

ALA 1332 0.06 VAL 300 -0.07 SER 174

GLY 84 0.07 GLY 301 -0.06 SER 174

GLY 84 0.09 CYS 302 -0.07 SER 174

GLY 84 0.15 GLN 303 -0.08 SER 174

GLY 84 0.15 VAL 304 -0.07 SER 174

GLN 82 0.20 SER 305 -0.07 SER 174

ARG 93 0.19 TYR 306 -0.06 ASN 1542

ARG 93 0.22 LYS 307 -0.06 ASN 1542

ARG 93 0.23 VAL 308 -0.05 ASN 1542

GLY 95 0.23 LYS 309 -0.06 GLU 1593

GLY 95 0.23 ASP 310 -0.07 GLU 1593

GLY 95 0.21 GLU 311 -0.06 GLU 1593

GLY 95 0.19 ARG 312 -0.07 GLU 1593

ARG 93 0.18 ILE 313 -0.07 GLU 1593

GLY 95 0.17 VAL 314 -0.08 GLU 1593

LYS 92 0.16 TYR 315 -0.07 GLU 1593

LYS 92 0.15 ALA 316 -0.06 ASN 1542

ALA 89 0.15 GLU 317 -0.09 SER 174

GLY 84 0.14 GLY 318 -0.11 SER 174

GLY 84 0.20 VAL 319 -0.14 SER 174

GLY 84 0.22 ASN 320 -0.15 SER 174

GLY 84 0.18 GLY 321 -0.12 SER 174

GLY 84 0.14 PRO 322 -0.11 SER 174

GLY 84 0.07 ALA 323 -0.10 PRO 456

GLN 227 0.07 ASN 324 -0.10 SER 174

GLY 84 0.13 GLN 325 -0.13 SER 174

GLY 84 0.14 ASN 326 -0.13 SER 174

ASP 1158 0.08 ARG 327 -0.11 SER 174

ASP 1158 0.08 LEU 328 -0.07 SER 174

ASP 1158 0.08 CYS 329 -0.07 ASN 1542

ASP 1158 0.09 VAL 330 -0.09 GLU 1593

ASP 1158 0.08 LYS 331 -0.08 GLU 1593

ASP 1158 0.08 GLY 332 -0.07 ASN 1542

LYS 92 0.09 ARG 333 -0.07 ASN 1542

LYS 92 0.10 PHE 334 -0.09 GLU 1593

LYS 92 0.09 GLY 335 -0.08 GLU 1593

ARG 93 0.12 PHE 336 -0.07 GLU 1593

GLY 95 0.12 ASP 337 -0.09 GLU 1593

GLY 95 0.11 TYR 338 -0.08 GLU 1593

ARG 93 0.13 VAL 339 -0.07 GLU 1593

GLY 95 0.14 HSD 340 -0.08 GLU 1593

GLY 95 0.14 HSD 341 -0.08 GLU 1593

GLY 95 0.14 PRO 342 -0.08 GLU 1593

GLY 95 0.12 HSD 343 -0.08 GLU 1593

GLY 95 0.13 ARG 344 -0.07 GLU 1593

GLY 95 0.13 LEU 345 -0.06 GLU 1593

GLY 95 0.14 THR 346 -0.05 GLU 1593

GLY 95 0.14 VAL 347 -0.05 GLU 1593

GLY 95 0.12 PRO 348 -0.05 GLU 1593

GLY 95 0.11 LEU 349 -0.05 GLU 1593

GLY 95 0.10 ILE 350 -0.05 GLU 1593

GLY 95 0.09 ARG 351 -0.06 GLU 1593

GLY 95 0.09 LEU 352 -0.06 GLU 1593

GLY 95 0.09 GLU 353 -0.06 GLU 1593

GLY 95 0.08 ASN 354 -0.06 GLU 1593

GLY 95 0.08 VAL 355 -0.07 GLU 1593

ALA 279 0.07 PRO 356 -0.07 GLU 1593

ALA 279 0.07 LYS 357 -0.07 GLU 1593

ALA 279 0.08 ASP 358 -0.07 GLU 1593

ALA 279 0.07 ALA 359 -0.08 GLU 1593

ALA 279 0.08 ASN 360 -0.08 GLU 1593

ALA 279 0.09 ASP 361 -0.08 GLU 1593

ALA 279 0.10 GLN 362 -0.08 GLU 1593

ALA 279 0.10 VAL 363 -0.08 GLU 1593

ALA 279 0.11 ASP 364 -0.09 GLU 1593

ALA 279 0.11 PRO 365 -0.08 GLU 1593

ALA 279 0.12 ALA 366 -0.09 GLU 1593

GLY 95 0.11 ASN 367 -0.08 GLU 1593

GLY 95 0.11 PRO 368 -0.07 GLU 1593

GLY 95 0.11 TRP 369 -0.07 GLU 1593

GLY 95 0.10 THR 370 -0.08 GLU 1593

GLY 95 0.09 HSD 371 -0.07 GLU 1593

GLY 95 0.10 PHE 372 -0.06 GLU 1593

GLY 95 0.11 ARG 373 -0.06 GLU 1593

GLY 95 0.12 GLU 374 -0.05 GLU 1593

GLY 95 0.12 ALA 375 -0.04 GLU 1593

GLY 95 0.13 THR 376 -0.03 GLU 1593

LEU 94 0.13 TRP 377 -0.03 GLU 1593

LEU 94 0.12 GLU 378 -0.03 ASN 1542

LEU 94 0.11 GLU 379 -0.03 GLU 1593

LEU 94 0.11 ALA 380 -0.04 GLU 1593

THR 69 0.11 LEU 381 -0.03 ASN 1542

THR 69 0.10 ASP 382 -0.03 ASN 1542

LEU 94 0.09 ARG 383 -0.03 GLU 1593

THR 69 0.09 ALA 384 -0.03 GLU 1593

THR 69 0.09 ALA 385 -0.03 ASN 1542

THR 69 0.09 GLY 386 -0.03 ASN 1542

THR 69 0.07 GLY 387 -0.03 GLU 1593

THR 69 0.07 LEU 388 -0.03 ASN 1542

THR 69 0.08 LYS 389 -0.03 ASN 1542

THR 69 0.07 ALA 390 -0.03 ASN 1542

THR 69 0.06 ILE 391 -0.03 GLU 1593

THR 69 0.06 ARG 392 -0.03 ASN 1542

THR 69 0.06 ASP 393 -0.03 ASN 1542

THR 69 0.05 THR 394 -0.03 ASN 1542

ALA 279 0.04 ASN 395 -0.03 ASN 1542

THR 69 0.04 GLY 396 -0.03 ASN 1542

THR 69 0.04 ARG 397 -0.03 ASN 1542

ALA 279 0.04 LYS 398 -0.04 ASN 1542

ALA 279 0.04 ALA 399 -0.04 ASN 1542

ALA 279 0.04 LEU 400 -0.04 ASN 1542

ALA 279 0.04 ALA 401 -0.04 ASN 1542

THR 69 0.05 GLY 402 -0.04 ASN 1542

ALA 279 0.05 PHE 403 -0.04 ASN 1542

THR 69 0.06 GLY 404 -0.04 ASN 1542

THR 69 0.06 SER 405 -0.05 ASN 1542

ASP 1158 0.05 ALA 406 -0.05 ASN 1542

THR 69 0.07 LYS 407 -0.05 ASN 1542

THR 69 0.09 GLY 408 -0.04 ASN 1542

THR 69 0.11 SER 409 -0.04 ASN 1542

THR 69 0.11 ASN 410 -0.04 ASN 1542

THR 69 0.13 GLU 411 -0.04 ASN 1542

THR 69 0.11 GLU 412 -0.04 ASN 1542

THR 69 0.09 ALA 413 -0.04 ASN 1542

THR 69 0.10 TYR 414 -0.04 ASN 1542

THR 69 0.11 LEU 415 -0.03 ASN 1542

THR 69 0.09 PHE 416 -0.04 ASN 1542

THR 69 0.07 GLN 417 -0.04 ASN 1542

THR 69 0.09 LYS 418 -0.03 ASN 1542

THR 69 0.09 LEU 419 -0.03 ASN 1542

THR 69 0.07 VAL 420 -0.04 ASN 1542

THR 69 0.06 ARG 421 -0.04 ASN 1542

THR 69 0.08 LEU 422 -0.03 ASN 1542

THR 69 0.08 GLY 423 -0.03 ASN 1542

THR 69 0.06 PHE 424 -0.03 ASN 1542

THR 69 0.06 GLY 425 -0.03 ASN 1542

THR 69 0.04 THR 426 -0.04 ASN 1542

ASP 1158 0.03 ASN 427 -0.04 ASN 1542

ALA 279 0.04 ASN 428 -0.04 ASN 1542

ASP 1158 0.04 VAL 429 -0.04 ASN 1542

ALA 1332 0.04 ASP 430 -0.05 ASN 1542

ALA 1332 0.04 HSD 431 -0.05 ASN 1542

ALA 1332 0.04 CYS 432 -0.05 ASN 1542

ALA 1332 0.04 THR 433 -0.05 ASN 1542

ALA 1332 0.04 ARG 434 -0.05 ASN 1542

ALA 279 0.04 LEU 435 -0.06 ASN 1542

ALA 1332 0.04 CYS 436 -0.06 GLY 108

GLU 1336 0.04 HSD 437 -0.07 GLY 108

GLU 1336 0.04 ALA 438 -0.06 GLY 108

GLU 1336 0.03 SER 439 -0.09 GLN 82

GLU 1336 0.04 SER 440 -0.10 GLN 82

GLU 1336 0.03 VAL 441 -0.08 ARG 93

GLU 1336 0.03 ALA 442 -0.09 GLN 82

GLU 1336 0.03 ALA 443 -0.12 GLN 82

GLU 1336 0.03 LEU 444 -0.12 GLN 82

MET 646 0.03 MET 445 -0.10 ARG 93

MET 646 0.02 GLU 446 -0.11 GLN 82

MET 646 0.02 GLY 447 -0.14 GLN 82

SER 653 0.02 LEU 448 -0.14 ARG 93

SER 653 0.03 ASN 449 -0.11 ARG 93

GLU 1336 0.03 SER 450 -0.11 ARG 93

GLU 1336 0.03 GLY 451 -0.10 ARG 93

GLU 1336 0.04 ALA 452 -0.11 ARG 93

GLU 1336 0.04 VAL 453 -0.13 ARG 93

GLU 1336 0.04 THR 454 -0.17 ARG 93

GLU 1336 0.05 ALA 455 -0.19 ARG 93

GLU 1336 0.05 PRO 456 -0.17 ARG 93

GLU 1336 0.06 PHE 457 -0.18 PRO 107

GLU 1336 0.06 SER 458 -0.24 PRO 107

GLU 1336 0.06 ALA 459 -0.25 ARG 93

GLU 1336 0.06 ALA 460 -0.26 GLN 82

GLU 1336 0.07 LEU 461 -0.31 GLN 82

GLU 1336 0.06 ASP 462 -0.37 GLN 82

GLU 1336 0.06 ALA 463 -0.35 GLN 82

GLU 1336 0.06 GLU 464 -0.40 PRO 83

GLU 1336 0.06 VAL 465 -0.34 PRO 83

GLU 1336 0.06 ILE 466 -0.28 PRO 83

GLU 1336 0.06 VAL 467 -0.24 PRO 83

GLU 1336 0.06 VAL 468 -0.19 PRO 83

GLU 1336 0.05 ILE 469 -0.17 PRO 83

GLU 1336 0.05 GLY 470 -0.14 PRO 83

GLU 1336 0.06 ALA 471 -0.13 PRO 83

ALA 1332 0.06 ASN 472 -0.12 GLY 84

GLU 1336 0.07 PRO 473 -0.13 GLY 108

ALA 1332 0.07 THR 474 -0.12 GLY 108

ALA 1332 0.07 VAL 475 -0.09 GLY 108

ALA 1332 0.07 ASN 476 -0.08 GLY 108

ALA 1332 0.07 HSD 477 -0.09 GLY 108

ALA 1332 0.07 PRO 478 -0.10 GLY 108

ALA 1332 0.07 VAL 479 -0.11 GLY 108

ALA 1332 0.06 ALA 480 -0.15 GLY 108

ALA 1332 0.07 ALA 481 -0.17 GLY 108

ALA 1332 0.08 THR 482 -0.21 GLY 108

GLU 1336 0.07 PHE 483 -0.27 GLY 108

GLU 1336 0.07 LEU 484 -0.23 GLY 108

GLU 1336 0.08 LYS 485 -0.23 GLY 108

GLU 1336 0.07 ASN 486 -0.35 GLY 108

GLU 1336 0.07 ALA 487 -0.32 GLY 84

GLU 1336 0.08 VAL 488 -0.34 GLY 84

GLN 1069 0.09 LYS 489 -0.37 GLY 84

GLN 1069 0.09 GLN 490 -0.46 GLY 84

GLU 1336 0.07 ARG 491 -0.50 GLY 84

GLU 1336 0.08 GLY 492 -0.47 GLY 84

GLU 1336 0.07 ALA 493 -0.40 GLY 84

GLU 1336 0.07 LYS 494 -0.36 GLY 84

GLU 1336 0.07 LEU 495 -0.29 GLY 84

GLU 1336 0.06 ILE 496 -0.26 PRO 83

GLU 1336 0.06 ILE 497 -0.22 GLY 84

GLU 1336 0.06 MET 498 -0.20 PRO 83

GLU 1336 0.06 ASP 499 -0.17 PRO 83

GLU 1336 0.06 PRO 500 -0.16 PRO 83

GLU 1336 0.07 ARG 501 -0.14 GLY 84

GLU 1336 0.08 ARG 502 -0.16 GLY 84

ALA 1332 0.08 GLN 503 -0.15 GLY 84

ALA 1332 0.08 THR 504 -0.15 GLY 84

GLU 1336 0.08 LEU 505 -0.18 GLY 84

GLU 1336 0.08 SER 506 -0.20 GLY 84

GLU 1336 0.09 ARG 507 -0.22 GLY 84

GLU 1336 0.09 HSD 508 -0.26 GLY 84

GLU 1336 0.08 ALA 509 -0.28 GLY 84

GLU 1336 0.08 TYR 510 -0.32 GLY 84

GLU 1336 0.07 ARG 511 -0.28 GLY 84

GLU 1336 0.07 HSD 512 -0.24 GLY 84

GLU 1336 0.06 LEU 513 -0.22 PRO 83

GLU 1336 0.06 ALA 514 -0.19 PRO 83

GLU 1336 0.05 PHE 515 -0.18 PRO 83

MET 942 0.05 ARG 516 -0.16 PRO 83

MET 942 0.04 PRO 517 -0.14 PRO 83

SER 872 0.04 GLY 518 -0.14 PRO 83

GLU 1336 0.03 SER 519 -0.16 PRO 83

GLU 1336 0.03 ASP 520 -0.17 PRO 83

GLU 1336 0.03 VAL 521 -0.17 PRO 83

VAL 870 0.02 ALA 522 -0.19 PRO 83

GLU 1336 0.03 MET 523 -0.21 PRO 83

GLU 1336 0.03 LEU 524 -0.21 PRO 83

ALA 522 0.02 ASN 525 -0.21 PRO 83

GLY 941 0.02 ALA 526 -0.23 PRO 83

ILE 940 0.02 MET 527 -0.25 PRO 83

GLY 941 0.02 LEU 528 -0.24 PRO 83

GLY 941 0.02 ASN 529 -0.25 THR 69

ILE 940 0.02 VAL 530 -0.27 THR 69

ILE 940 0.02 ILE 531 -0.29 THR 69

ILE 940 0.02 VAL 532 -0.27 THR 69

ILE 940 0.02 THR 533 -0.28 THR 69

ILE 940 0.02 GLU 534 -0.31 THR 69

ILE 940 0.02 GLY 535 -0.31 THR 69

PRO 1053 0.02 LEU 536 -0.33 THR 69

PRO 1053 0.02 TYR 537 -0.31 THR 69

LYS 656 0.02 ASP 538 -0.32 THR 69

LYS 656 0.02 GLU 539 -0.30 THR 69

LYS 656 0.02 GLN 540 -0.31 THR 69

LYS 656 0.02 TYR 541 -0.28 GLN 82

LYS 656 0.02 ILE 542 -0.25 THR 69

LYS 656 0.02 ALA 543 -0.25 THR 69

LYS 656 0.03 GLY 544 -0.23 GLN 82

LYS 656 0.03 TYR 545 -0.22 GLN 82

LYS 656 0.02 THR 546 -0.21 GLN 82

GLU 655 0.02 GLU 547 -0.19 GLN 82

LEU 965 0.02 ASN 548 -0.19 THR 69

PRO 853 0.02 PHE 549 -0.21 THR 69

PRO 964 0.02 GLU 550 -0.21 THR 69

PRO 964 0.02 ALA 551 -0.19 THR 69

PRO 853 0.03 LEU 552 -0.21 THR 69

ALA 855 0.02 ARG 553 -0.23 THR 69

ALA 855 0.02 GLU 554 -0.21 THR 69

ALA 855 0.03 LYS 555 -0.20 THR 69

ALA 855 0.02 ILE 556 -0.21 THR 69

ASP 864 0.02 VAL 557 -0.22 THR 69

VAL 862 0.03 ASP 558 -0.21 THR 69

VAL 862 0.03 PHE 559 -0.21 THR 69

GLY 941 0.02 THR 560 -0.23 THR 69

GLY 941 0.03 PRO 561 -0.24 PRO 83

GLY 941 0.03 GLU 562 -0.23 PRO 83

GLY 941 0.03 LYS 563 -0.21 PRO 83

GLY 941 0.03 MET 564 -0.21 PRO 83

GLY 941 0.04 ALA 565 -0.22 PRO 83

GLY 941 0.04 SER 566 -0.20 PRO 83

GLY 941 0.04 VAL 567 -0.18 PRO 83

GLY 941 0.04 CYS 568 -0.19 PRO 83

ILE 940 0.05 GLY 569 -0.20 PRO 83

ILE 940 0.04 ILE 570 -0.22 PRO 83

ILE 940 0.04 ASP 571 -0.24 PRO 83

ILE 940 0.03 ALA 572 -0.26 PRO 83

ILE 940 0.03 GLU 573 -0.28 PRO 83

GLU 1336 0.04 THR 574 -0.28 PRO 83

ILE 940 0.03 LEU 575 -0.27 PRO 83

ILE 940 0.03 ARG 576 -0.29 PRO 83

GLU 1336 0.03 GLU 577 -0.32 PRO 83

GLU 1336 0.04 VAL 578 -0.30 PRO 83

GLU 1336 0.02 ALA 579 -0.30 PRO 83

PRO 1053 0.02 ARG 580 -0.34 PRO 83

GLU 1336 0.04 LEU 581 -0.36 PRO 83

GLU 1336 0.04 TYR 582 -0.32 PRO 83

PRO 1053 0.03 ALA 583 -0.33 PRO 83

PRO 1053 0.03 ARG 584 -0.38 PRO 83

GLU 1336 0.04 ALA 585 -0.40 PRO 83

GLU 1336 0.04 LYS 586 -0.42 PRO 83

GLU 1336 0.04 SER 587 -0.37 GLN 82

GLU 1336 0.05 SER 588 -0.31 GLN 82

GLU 1336 0.05 LEU 589 -0.25 GLN 82

GLU 1336 0.05 ILE 590 -0.21 GLN 82

GLU 1336 0.05 PHE 591 -0.17 GLN 82

GLU 1336 0.05 TRP 592 -0.14 GLN 82

GLU 1336 0.05 GLY 593 -0.11 PRO 83

GLU 1336 0.05 MET 594 -0.09 PRO 83

GLU 1336 0.05 GLY 595 -0.12 PRO 83

GLU 1336 0.04 VAL 596 -0.13 PRO 83

GLU 1336 0.04 SER 597 -0.10 PRO 83

GLU 1336 0.04 GLN 598 -0.09 PRO 83

ALA 279 0.04 HSD 599 -0.10 PRO 83

ALA 279 0.04 VAL 600 -0.10 PRO 83

ALA 279 0.03 HSD 601 -0.12 PRO 83

GLU 1336 0.03 GLY 602 -0.12 PRO 83

GLU 1336 0.03 THR 603 -0.12 GLN 82

GLU 1336 0.02 ASP 604 -0.14 GLN 82

GLU 1336 0.03 ASN 605 -0.15 PRO 83

GLU 1336 0.03 SER 606 -0.15 GLN 82

GLU 1336 0.02 ARG 607 -0.16 GLN 82

GLU 1336 0.02 CYS 608 -0.18 GLN 82

GLU 1336 0.03 LEU 609 -0.19 GLN 82

GLU 1336 0.03 ILE 610 -0.18 GLN 82

GLU 1336 0.02 ALA 611 -0.20 GLN 82

GLU 1336 0.02 LEU 612 -0.23 GLN 82

GLU 1336 0.03 ALA 613 -0.24 GLN 82

GLU 1336 0.02 LEU 614 -0.23 GLN 82

PRO 1053 0.01 ILE 615 -0.25 GLN 82

PRO 1053 0.02 THR 616 -0.29 GLN 82

GLU 1336 0.02 GLY 617 -0.29 GLN 82

GLU 1336 0.03 GLN 618 -0.29 GLN 82

GLU 1336 0.03 ILE 619 -0.25 GLN 82

GLU 1336 0.03 GLY 620 -0.24 GLN 82

GLU 1336 0.04 ARG 621 -0.29 GLN 82

GLU 1336 0.05 PRO 622 -0.31 GLN 82

GLU 1336 0.05 GLY 623 -0.32 GLN 82

GLU 1336 0.04 THR 624 -0.28 GLN 82

GLU 1336 0.04 GLY 625 -0.22 GLN 82

GLU 1336 0.04 LEU 626 -0.18 GLN 82

GLU 1336 0.05 HSD 627 -0.15 ARG 93

GLU 1336 0.05 PRO 628 -0.11 GLN 82

GLU 1336 0.05 LEU 629 -0.10 GLY 108

ALA 1332 0.05 ARG 630 -0.07 GLY 108

ALA 1332 0.05 GLY 631 -0.06 GLY 108

ALA 1332 0.06 GLN 632 -0.06 ASN 1542

ASP 1158 0.06 ASN 633 -0.06 ASN 1542

PRO 83 0.06 ASN 634 -0.05 ASN 1542

ALA 1332 0.05 VAL 635 -0.05 ASN 1542

ALA 1332 0.05 GLN 636 -0.05 ASN 1542

PRO 83 0.06 GLY 637 -0.05 ASN 1542

THR 69 0.05 ALA 638 -0.05 ASN 1542

ALA 1332 0.04 SER 639 -0.05 ASN 1542

PRO 83 0.05 ASP 640 -0.05 ASN 1542

PRO 83 0.07 ALA 641 -0.04 ASN 1542

THR 69 0.05 GLY 642 -0.04 ASN 1542

THR 69 0.04 LEU 643 -0.04 ASN 1542

ALA 1332 0.04 ILE 644 -0.05 ASN 1542

ALA 1332 0.03 PRO 645 -0.04 ASN 1542

GLU 845 0.03 MET 646 -0.04 ASN 1542

ALA 1332 0.03 VAL 647 -0.04 ASN 1542

PRO 83 0.04 TYR 648 -0.04 ASN 1542

PRO 83 0.06 PRO 649 -0.04 ASN 1542

GLY 84 0.04 ASP 650 -0.04 SER 174

GLU 1336 0.03 TYR 651 -0.05 GLY 95

PRO 843 0.04 GLN 652 -0.04 GLY 95

GLU 845 0.04 SER 653 -0.04 ASN 1542

GLU 845 0.04 VAL 654 -0.04 ASN 1542

GLU 845 0.05 GLU 655 -0.04 ASN 1542

GLU 845 0.05 LYS 656 -0.04 GLY 95

GLU 845 0.04 ASP 657 -0.04 ASN 1542

GLU 845 0.04 ALA 658 -0.03 ASN 1542

PRO 83 0.04 VAL 659 -0.04 ASN 1542

PRO 83 0.04 ARG 660 -0.03 ASN 1542

THR 69 0.05 GLU 661 -0.03 ASN 1542

THR 69 0.07 LEU 662 -0.03 ASN 1542

THR 69 0.07 PHE 663 -0.03 ASN 1542

THR 69 0.07 GLU 664 -0.03 ASN 1542

THR 69 0.09 GLU 665 -0.03 ASN 1542

THR 69 0.10 PHE 666 -0.03 ASN 1542

THR 69 0.10 TRP 667 -0.03 ASN 1542

THR 69 0.10 GLY 668 -0.03 ASN 1542

THR 69 0.09 GLN 669 -0.03 ASN 1542

THR 69 0.07 SER 670 -0.03 ASN 1542

THR 69 0.05 LEU 671 -0.03 ASN 1542

THR 69 0.04 ASP 672 -0.04 ASN 1542

GLU 845 0.04 PRO 673 -0.04 ASN 1542

GLU 845 0.04 GLN 674 -0.04 ASN 1542

GLU 845 0.04 LYS 675 -0.04 ASN 1542

ALA 279 0.03 GLY 676 -0.04 ASN 1542

ALA 279 0.04 LEU 677 -0.04 ASN 1542

ALA 279 0.04 THR 678 -0.05 ASN 1542

ALA 279 0.04 VAL 679 -0.05 ASN 1542

ALA 279 0.05 VAL 680 -0.05 GLU 1593

ALA 279 0.04 GLU 681 -0.05 GLU 1593

ALA 279 0.05 ILE 682 -0.05 GLU 1593

ALA 279 0.05 MET 683 -0.05 GLU 1593

ALA 279 0.05 ARG 684 -0.05 GLU 1593

ALA 279 0.05 ALA 685 -0.05 GLU 1593

ALA 279 0.05 ILE 686 -0.05 GLU 1593

ALA 279 0.05 HSD 687 -0.06 GLU 1593

ALA 279 0.05 ALA 688 -0.05 GLU 1593

ALA 279 0.05 GLY 689 -0.05 GLU 1593

ALA 279 0.05 GLU 690 -0.04 GLU 1593

ALA 279 0.05 ILE 691 -0.04 GLU 1593

ALA 279 0.05 ARG 692 -0.04 GLU 1593

ALA 279 0.05 GLY 693 -0.04 GLU 1593

ALA 279 0.05 MET 694 -0.04 GLU 1593

THR 69 0.06 PHE 695 -0.04 GLU 1593

THR 69 0.06 VAL 696 -0.04 GLU 1593

THR 69 0.07 GLU 697 -0.04 ASN 1542

THR 69 0.07 GLY 698 -0.05 GLU 1593

ALA 279 0.06 GLU 699 -0.05 GLU 1593

ALA 279 0.06 ASN 700 -0.06 GLU 1593

ALA 279 0.06 PRO 701 -0.06 GLU 1593

ALA 279 0.07 ALA 702 -0.07 GLU 1593

ALA 279 0.07 MET 703 -0.08 GLU 1593

ALA 279 0.06 SER 704 -0.07 GLU 1593

ALA 279 0.06 ASP 705 -0.07 GLU 1593

ALA 279 0.06 PRO 706 -0.07 GLU 1593

ALA 279 0.06 ASP 707 -0.07 GLU 1593

ALA 279 0.07 LEU 708 -0.08 GLU 1593

ALA 279 0.07 ASN 709 -0.08 GLU 1593

ALA 279 0.06 HSD 710 -0.07 GLU 1593

ALA 279 0.06 ALA 711 -0.07 GLU 1593

ALA 279 0.07 ARG 712 -0.07 GLU 1593

ALA 279 0.07 HSD 713 -0.07 GLU 1593

ALA 279 0.06 ALA 714 -0.06 GLU 1593

ALA 279 0.06 LEU 715 -0.06 GLU 1593

ALA 279 0.07 ALA 716 -0.06 GLU 1593

ALA 279 0.06 MET 717 -0.06 GLU 1593

ALA 279 0.06 LEU 718 -0.05 GLU 1593

ALA 279 0.06 ASP 719 -0.05 GLU 1593

GLY 95 0.06 HSD 720 -0.05 GLU 1593

GLY 95 0.06 LEU 721 -0.05 GLU 1593

GLY 95 0.07 VAL 722 -0.04 GLU 1593

GLY 95 0.07 VAL 723 -0.05 GLU 1593

ARG 93 0.09 GLN 724 -0.04 GLU 1593

ARG 93 0.09 ASP 725 -0.05 GLU 1593

GLY 95 0.10 LEU 726 -0.06 GLU 1593

GLY 95 0.10 PHE 727 -0.07 GLU 1593

GLY 95 0.09 LEU 728 -0.07 GLU 1593

ALA 279 0.08 THR 729 -0.07 GLU 1593

ALA 279 0.08 GLU 730 -0.08 GLU 1593

ALA 279 0.07 THR 731 -0.07 GLU 1593

ALA 279 0.07 ALA 732 -0.06 GLU 1593

ALA 279 0.08 PHE 733 -0.07 GLU 1593

ALA 279 0.07 HSD 734 -0.06 GLU 1593

GLY 95 0.07 ALA 735 -0.06 GLU 1593

GLY 95 0.08 ASP 736 -0.05 GLU 1593

GLY 95 0.09 VAL 737 -0.05 GLU 1593

GLY 95 0.09 VAL 738 -0.05 GLU 1593

ARG 93 0.10 LEU 739 -0.04 GLU 1593

ARG 93 0.12 PRO 740 -0.04 GLU 1593

ARG 93 0.12 ALA 741 -0.04 GLU 1593

ARG 93 0.13 SER 742 -0.04 ASN 1542

ARG 93 0.12 ALA 743 -0.05 ASN 1542

GLN 82 0.13 PHE 744 -0.05 ASN 1542

GLN 82 0.16 ALA 745 -0.05 ASN 1542

ARG 93 0.17 GLU 746 -0.04 ASN 1542

GLN 82 0.17 LYS 747 -0.04 ASN 1542

GLN 82 0.18 ALA 748 -0.04 ASN 1542

THR 69 0.17 GLY 749 -0.04 ASN 1542

PRO 83 0.15 THR 750 -0.05 LYS 292

PRO 83 0.11 PHE 751 -0.05 LYS 292

GLY 84 0.08 THR 752 -0.06 SER 174

ALA 1332 0.05 ASN 753 -0.07 SER 174

ALA 1332 0.05 THR 754 -0.07 SER 174

GLU 1336 0.05 ASP 755 -0.10 GLY 95

GLU 1336 0.05 ARG 756 -0.08 GLY 95

GLY 84 0.09 ARG 757 -0.08 SER 174

PRO 83 0.13 VAL 758 -0.07 SER 174

PRO 83 0.16 GLN 759 -0.07 SER 174

PRO 83 0.19 ILE 760 -0.07 LYS 292

GLN 82 0.18 ALA 761 -0.07 LYS 292

GLN 82 0.22 GLN 762 -0.04 ASN 1542

GLN 82 0.21 PRO 763 -0.04 ASN 1542

ARG 93 0.22 VAL 764 -0.04 ASN 1542

ARG 93 0.22 VAL 765 -0.04 ASN 1542

ARG 93 0.20 ALA 766 -0.04 ASN 1542

ARG 93 0.17 PRO 767 -0.04 ASN 1542

GLY 95 0.17 PRO 768 -0.05 GLU 1593

GLY 95 0.17 GLY 769 -0.04 GLU 1593

GLY 95 0.16 ASP 770 -0.04 GLU 1593

ARG 93 0.14 ALA 771 -0.04 GLU 1593

ARG 93 0.14 ARG 772 -0.04 ASN 1542

GLN 82 0.15 GLN 773 -0.03 ASN 1542

THR 69 0.13 ASP 774 -0.04 ASN 1542

THR 69 0.14 TRP 775 -0.03 ASN 1542

THR 69 0.15 TRP 776 -0.03 ASN 1542

THR 69 0.13 ILE 777 -0.03 ASN 1542

THR 69 0.11 ILE 778 -0.03 ASN 1542

THR 69 0.13 GLN 779 -0.03 ASN 1542

THR 69 0.13 GLU 780 -0.03 ASN 1542

THR 69 0.11 LEU 781 -0.03 ASN 1542

THR 69 0.11 ALA 782 -0.03 ASN 1542

THR 69 0.12 ARG 783 -0.03 ASN 1542

THR 69 0.11 ARG 784 -0.03 ASN 1542

THR 69 0.10 LEU 785 -0.03 ASN 1542

THR 69 0.11 ASP 786 -0.03 ASN 1542

THR 69 0.12 LEU 787 -0.03 ASN 1542

THR 69 0.13 ASP 788 -0.02 ASN 1542

THR 69 0.14 TRP 789 -0.03 ASN 1542

THR 69 0.16 ASN 790 -0.02 ASN 1542

THR 69 0.17 TYR 791 -0.03 ASN 1542

THR 69 0.20 GLY 792 -0.02 ASN 1542

THR 69 0.19 GLY 793 -0.03 ASN 1542

THR 69 0.18 PRO 794 -0.03 ASN 1542

THR 69 0.20 ALA 795 -0.03 ASN 1542

THR 69 0.19 ASP 796 -0.03 ASN 1542

THR 69 0.16 ILE 797 -0.03 ASN 1542

THR 69 0.16 PHE 798 -0.03 ASN 1542

THR 69 0.18 ALA 799 -0.03 SER 174

THR 69 0.15 GLU 800 -0.03 ASN 1542

THR 69 0.13 MET 801 -0.03 ASN 1542

PRO 83 0.14 ALA 802 -0.04 SER 174

THR 69 0.13 GLN 803 -0.04 SER 174

PRO 83 0.10 VAL 804 -0.04 SER 174

PRO 83 0.09 MET 805 -0.05 SER 174

PRO 83 0.09 PRO 806 -0.05 SER 174

PRO 83 0.08 SER 807 -0.06 SER 174

PRO 83 0.12 LEU 808 -0.06 SER 174

PRO 83 0.13 ASN 809 -0.06 SER 174

PRO 83 0.18 ASN 810 -0.07 SER 174

PRO 83 0.19 ILE 811 -0.07 SER 174

PRO 83 0.21 THR 812 -0.06 SER 174

THR 69 0.23 TRP 813 -0.05 SER 174

THR 69 0.28 GLU 814 -0.06 SER 174

PRO 83 0.28 ARG 815 -0.08 SER 174

PRO 83 0.25 LEU 816 -0.08 SER 174

GLN 82 0.29 GLU 817 -0.07 SER 174

GLN 82 0.34 ARG 818 -0.09 SER 174

PRO 83 0.32 GLU 819 -0.11 SER 174

PRO 83 0.26 GLY 820 -0.09 SER 174

PRO 83 0.20 ALA 821 -0.10 SER 174

PRO 83 0.17 VAL 822 -0.09 SER 174

GLY 84 0.11 THR 823 -0.10 GLY 95

GLY 84 0.08 TYR 824 -0.09 GLY 95

GLY 84 0.07 PRO 825 -0.11 GLY 95

GLY 84 0.11 VAL 826 -0.12 GLY 95

PRO 83 0.12 ASP 827 -0.13 GLY 95

PRO 83 0.18 ALA 828 -0.11 GLY 95

PRO 83 0.24 PRO 829 -0.09 SER 174

PRO 83 0.28 ASP 830 -0.11 GLY 95

PRO 83 0.22 GLN 831 -0.16 GLY 95

GLY 84 0.17 PRO 832 -0.17 GLY 95

GLY 84 0.10 GLY 833 -0.15 GLY 95

GLU 1336 0.05 ASN 834 -0.18 GLY 95

GLU 1336 0.05 GLU 835 -0.19 ARG 93

GLU 1336 0.04 ILE 836 -0.21 ARG 93

GLU 1336 0.04 ILE 837 -0.19 ARG 93

GLU 1336 0.03 PHE 838 -0.19 ARG 93

GLU 1336 0.03 TYR 839 -0.23 ARG 93

LYS 656 0.03 ALA 840 -0.21 ARG 93

LYS 656 0.03 GLY 841 -0.19 ARG 93

SER 653 0.03 PHE 842 -0.16 ARG 93

SER 653 0.04 PRO 843 -0.13 ARG 93

SER 653 0.04 THR 844 -0.13 ARG 93

LYS 656 0.05 GLU 845 -0.12 LEU 94

LYS 656 0.04 SER 846 -0.14 LEU 94

LYS 656 0.04 GLY 847 -0.16 ARG 93

LYS 656 0.03 ARG 848 -0.17 GLN 82

GLU 655 0.02 ALA 849 -0.17 GLN 82

LEU 965 0.02 LYS 850 -0.17 GLN 82

LEU 965 0.02 ILE 851 -0.18 GLN 82

LEU 965 0.03 VAL 852 -0.16 GLN 82

LEU 552 0.03 PRO 853 -0.17 THR 69

LEU 552 0.02 ALA 854 -0.16 THR 69

LYS 555 0.03 ALA 855 -0.16 THR 69

ALA 279 0.03 ILE 856 -0.16 PRO 83

ALA 279 0.03 VAL 857 -0.14 PRO 83

VAL 862 0.04 PRO 858 -0.13 PRO 83

GLU 861 0.04 PRO 859 -0.12 PRO 83

ALA 279 0.04 ASP 860 -0.10 PRO 83

ALA 279 0.05 GLU 861 -0.10 PRO 83

ALA 279 0.05 VAL 862 -0.11 PRO 83

ALA 279 0.05 PRO 863 -0.11 PRO 83

ALA 279 0.05 ASP 864 -0.11 PRO 83

ALA 279 0.05 ASP 865 -0.10 PRO 83

ALA 279 0.06 GLU 866 -0.09 GLU 1593

ALA 279 0.06 PHE 867 -0.09 PRO 83

ALA 279 0.05 PRO 868 -0.11 PRO 83

ALA 279 0.06 MET 869 -0.10 PRO 83

ALA 279 0.05 VAL 870 -0.11 PRO 83

ALA 279 0.06 LEU 871 -0.09 PRO 83

ALA 1332 0.05 SER 872 -0.09 GLY 84

ALA 279 0.06 THR 873 -0.08 GLU 1593

ALA 1332 0.06 GLY 874 -0.08 GLU 1593

ALA 1332 0.06 ARG 875 -0.08 GLU 1593

ALA 1332 0.07 VAL 876 -0.09 GLU 1593

ALA 1332 0.07 LEU 877 -0.09 GLU 1593

ASP 1158 0.08 GLU 878 -0.10 GLU 1593

ALA 279 0.07 HSD 879 -0.09 GLU 1593

ASP 1158 0.06 TRP 880 -0.08 GLU 1593

ALA 279 0.06 HSD 881 -0.08 GLU 1593

ALA 279 0.07 THR 882 -0.08 GLU 1593

ALA 279 0.08 GLY 883 -0.09 GLU 1593

ALA 279 0.08 SER 884 -0.08 GLU 1593

GLY 95 0.08 MET 885 -0.08 GLU 1593

ALA 279 0.08 THR 886 -0.09 GLU 1593

ALA 279 0.10 ARG 887 -0.10 GLU 1593

ASP 278 0.11 ARG 888 -0.09 GLU 1593

ASP 278 0.10 ALA 889 -0.10 GLU 1593

ALA 275 0.14 GLY 890 -0.11 GLU 1593

ALA 275 0.12 VAL 891 -0.11 GLU 1593

ALA 279 0.09 LEU 892 -0.11 GLU 1593

ALA 279 0.12 ASP 893 -0.11 GLU 1593

ALA 279 0.14 ALA 894 -0.13 GLU 1593

ALA 279 0.11 LEU 895 -0.12 GLU 1593

ALA 279 0.10 GLU 896 -0.12 GLU 1593

ALA 279 0.13 PRO 897 -0.12 GLU 1593

ALA 279 0.12 GLU 898 -0.12 GLU 1593

ALA 279 0.10 ALA 899 -0.11 GLU 1593

ALA 279 0.09 VAL 900 -0.12 GLU 1593

ALA 279 0.08 ALA 901 -0.11 GLU 1593

ALA 1332 0.07 PHE 902 -0.11 GLU 1593

ALA 1332 0.07 MET 903 -0.11 GLU 1593

ALA 1332 0.08 ALA 904 -0.12 GLY 84

ALA 1332 0.09 PRO 905 -0.12 GLU 1593

ALA 1332 0.08 LYS 906 -0.12 GLY 84

LYS 1333 0.07 GLU 907 -0.11 GLU 1593

ALA 1332 0.08 LEU 908 -0.12 GLU 1593

LYS 1333 0.08 TYR 909 -0.13 GLU 1593

LYS 1333 0.07 ARG 910 -0.12 GLU 1593

LYS 1333 0.07 LEU 911 -0.12 GLU 1593

LYS 1333 0.07 GLY 912 -0.13 GLU 1593

ALA 279 0.08 LEU 913 -0.13 GLU 1593

ALA 1332 0.08 ARG 914 -0.14 GLU 1593

ALA 1332 0.09 PRO 915 -0.14 GLU 1593

ALA 279 0.10 GLY 916 -0.14 GLU 1593

ALA 279 0.10 GLY 917 -0.13 GLU 1593

ALA 279 0.10 SER 918 -0.12 GLU 1593

ALA 279 0.09 MET 919 -0.12 GLU 1593

ALA 279 0.09 ARG 920 -0.11 GLU 1593

ALA 279 0.08 LEU 921 -0.10 GLU 1593

ALA 279 0.07 GLU 922 -0.10 GLU 1593

ALA 279 0.07 THR 923 -0.09 GLU 1593

ALA 279 0.06 ARG 924 -0.08 GLU 1593

ALA 279 0.07 ARG 925 -0.08 GLU 1593

ALA 279 0.07 GLY 926 -0.09 GLU 1593

ALA 279 0.08 ALA 927 -0.09 GLU 1593

ALA 279 0.09 VAL 928 -0.10 GLU 1593

ALA 279 0.10 VAL 929 -0.11 GLU 1593

ALA 279 0.10 LEU 930 -0.11 GLU 1593

ALA 279 0.10 LYS 931 -0.12 GLU 1593

ALA 279 0.08 VAL 932 -0.12 GLU 1593

ALA 1332 0.08 ARG 933 -0.12 GLU 1593

ALA 1332 0.09 SER 934 -0.12 GLU 1593

ALA 1332 0.09 ASP 935 -0.12 GLU 1593

ALA 1332 0.09 ARG 936 -0.14 GLY 84

ALA 1332 0.08 ASP 937 -0.14 GLY 84

ALA 1332 0.07 VAL 938 -0.13 GLY 84

GLU 1336 0.07 PRO 939 -0.14 GLY 84

LYS 1333 0.07 ILE 940 -0.13 PRO 83

LYS 1333 0.06 GLY 941 -0.12 PRO 83

LYS 1333 0.06 MET 942 -0.12 PRO 83

ALA 1332 0.06 ILE 943 -0.10 GLU 1593

ALA 1332 0.06 PHE 944 -0.10 GLU 1593

ALA 279 0.07 MET 945 -0.10 GLU 1593

ALA 279 0.07 PRO 946 -0.09 GLU 1593

ALA 279 0.07 PHE 947 -0.09 GLU 1593

ALA 279 0.08 CYS 948 -0.09 GLU 1593

ALA 279 0.09 TYR 949 -0.10 GLU 1593

ALA 279 0.10 ALA 950 -0.09 GLU 1593

ALA 279 0.11 GLU 951 -0.10 GLU 1593

ALA 279 0.09 ALA 952 -0.10 GLU 1593

ALA 279 0.08 ALA 953 -0.09 GLU 1593

ALA 279 0.07 ALA 954 -0.09 GLU 1593

ALA 279 0.07 ASN 955 -0.08 GLU 1593

ALA 279 0.07 LEU 956 -0.09 GLU 1593

ALA 279 0.07 LEU 957 -0.08 GLU 1593

ALA 279 0.06 THR 958 -0.08 GLU 1593

ALA 279 0.05 ASN 959 -0.07 GLU 1593

ALA 279 0.05 PRO 960 -0.07 GLU 1593

ALA 279 0.05 ALA 961 -0.07 PRO 83

ALA 279 0.04 LEU 962 -0.07 PRO 83

ALA 279 0.03 ASP 963 -0.08 PRO 83

ALA 279 0.03 PRO 964 -0.08 GLN 82

ALA 279 0.03 LEU 965 -0.08 GLN 82

ALA 279 0.03 GLY 966 -0.07 GLN 82

ALA 279 0.04 LYS 967 -0.06 GLY 108

ALA 279 0.04 ILE 968 -0.06 GLY 108

ALA 279 0.05 PRO 969 -0.06 PRO 83

ALA 279 0.05 GLU 970 -0.08 PRO 83

ALA 279 0.05 PHE 971 -0.07 PRO 83

ALA 279 0.05 LYS 972 -0.10 PRO 83

ALA 279 0.05 PHE 973 -0.10 PRO 83

ALA 279 0.05 CYS 974 -0.09 PRO 83

ALA 279 0.06 ALA 975 -0.09 PRO 83

ALA 279 0.06 ALA 976 -0.09 GLU 1593

ALA 279 0.07 ARG 977 -0.10 GLU 1593

ALA 279 0.07 VAL 978 -0.11 GLU 1593

ALA 279 0.08 VAL 979 -0.11 GLU 1593

ALA 279 0.08 PRO 980 -0.12 GLU 1593

ALA 279 0.09 ALA 981 -0.12 GLU 1593

ALA 279 0.10 GLU 982 -0.13 GLU 1593

ALA 279 0.12 ALA 983 -0.13 GLU 1593

ALA 279 0.13 ALA 984 -0.13 GLU 1593

ALA 279 0.12 PRO 985 -0.12 GLU 1593

ALA 279 0.11 MET 986 -0.11 GLU 1593

ALA 279 0.12 ALA 987 -0.11 GLU 1593

ALA 279 0.13 ALA 988 -0.12 GLU 1593

ALA 279 0.12 GLU 989 -0.12 GLU 1593

ALA 279 0.10 MET 1022 -0.10 GLU 1593

ALA 279 0.10 SER 1023 -0.10 GLU 1593

ALA 279 0.09 GLU 1024 -0.10 GLU 1593

ALA 279 0.09 ALA 1025 -0.10 GLU 1593

ALA 279 0.09 SER 1026 -0.10 GLU 1593

ALA 279 0.10 GLY 1027 -0.10 GLU 1593

ALA 279 0.10 THR 1028 -0.10 GLU 1593

ALA 279 0.11 VAL 1029 -0.10 GLU 1593

ALA 279 0.10 ARG 1030 -0.10 GLU 1593

ALA 279 0.11 SER 1031 -0.11 GLU 1593

ALA 279 0.12 PHE 1032 -0.10 GLU 1593

ALA 279 0.13 ALA 1033 -0.10 GLU 1593

ALA 279 0.14 HSD 1034 -0.10 GLU 1593

ALA 279 0.17 PRO 1035 -0.12 GLU 1593

ALA 279 0.16 GLY 1036 -0.12 GLU 1593

ALA 279 0.16 ARG 1037 -0.13 GLU 1593

ALA 279 0.19 GLY 1038 -0.14 GLU 1593

ALA 279 0.18 ARG 1039 -0.14 GLU 1593

ALA 279 0.15 ASN 1040 -0.14 GLU 1593

ALA 279 0.14 VAL 1041 -0.14 GLU 1593

ALA 279 0.12 ALA 1042 -0.13 GLU 1593

ALA 279 0.10 ARG 1043 -0.14 GLU 1593

ALA 1332 0.09 ALA 1044 -0.14 GLU 1593

ALA 1332 0.10 VAL 1045 -0.13 GLU 1593

ALA 1332 0.10 PRO 1046 -0.12 GLU 1593

ALA 1332 0.09 LYS 1047 -0.13 GLU 1593

ALA 1332 0.10 GLY 1048 -0.14 GLU 1593

ALA 1332 0.12 ARG 1049 -0.14 GLU 1593

ALA 1332 0.12 GLN 1050 -0.13 GLU 1593

ALA 1332 0.13 VAL 1051 -0.12 GLY 84

ALA 1332 0.14 ASP 1052 -0.13 GLU 1593

ALA 1332 0.14 PRO 1053 -0.13 GLY 84

ALA 1332 0.16 HSD 1054 -0.12 GLY 84

ALA 1332 0.16 ALA 1055 -0.13 GLY 84

ALA 1332 0.17 LYS 1056 -0.14 GLY 84

ALA 1332 0.19 VAL 1057 -0.14 PRO 83

ALA 1332 0.20 GLU 1058 -0.14 PRO 83

ALA 1332 0.20 ILE 1059 -0.15 PRO 83

ALA 1332 0.21 GLU 1060 -0.17 PRO 83

ALA 1332 0.24 GLU 1061 -0.16 PRO 83

ALA 1332 0.25 LEU 1062 -0.16 PRO 83

ALA 1332 0.25 LEU 1063 -0.18 PRO 83

ALA 1332 0.28 GLY 1064 -0.18 PRO 83

ALA 1332 0.29 THR 1065 -0.20 PRO 83

ALA 1332 0.27 ARG 1066 -0.21 PRO 83

ARG 1340 0.22 PRO 1067 -0.23 PRO 83

ARG 1340 0.17 ARG 1068 -0.23 GLY 84

ARG 1340 0.15 GLN 1069 -0.26 GLY 84

ARG 1340 0.11 ARG 1070 -0.25 GLY 84

ILE 1341 0.12 ASP 1071 -0.26 GLY 84

ILE 1341 0.16 LEU 1072 -0.23 GLY 84

ALA 1332 0.12 LEU 1073 -0.21 GLY 84

ALA 1328 0.13 ILE 1074 -0.20 GLY 84

ALA 1328 0.18 GLU 1075 -0.20 PRO 83

ALA 1328 0.18 HSD 1076 -0.18 GLY 84

ALA 1328 0.16 LEU 1077 -0.17 GLY 84

ALA 1328 0.18 HSD 1078 -0.17 PRO 83

ALA 1328 0.23 LEU 1079 -0.17 PRO 83

ALA 1328 0.19 ILE 1080 -0.15 GLY 84

ALA 1328 0.16 GLN 1081 -0.14 GLY 84

GLU 1325 0.21 ASP 1082 -0.14 PRO 83

ARG 1329 0.21 THR 1083 -0.14 PRO 83

ARG 1329 0.17 TYR 1084 -0.13 PRO 83

HSD 1202 0.18 GLY 1085 -0.17 ILE 1126

HSD 1202 0.15 GLN 1086 -0.12 GLY 84

ALA 1328 0.14 ILE 1087 -0.13 GLY 84

ARG 1329 0.13 SER 1088 -0.13 GLU 1593

ALA 1332 0.12 ALA 1089 -0.14 GLU 1593

ALA 1332 0.14 ASP 1090 -0.13 GLU 1593

ALA 1332 0.16 HSD 1091 -0.13 GLY 84

ALA 1332 0.14 LEU 1092 -0.14 GLY 84

ALA 1332 0.14 ALA 1093 -0.13 GLY 84

ALA 1332 0.15 ALA 1094 -0.15 GLY 84

ALA 1332 0.16 LEU 1095 -0.17 GLY 84

ALA 1332 0.13 ALA 1096 -0.17 GLY 84

ALA 1332 0.14 ASP 1097 -0.17 GLY 84

ALA 1332 0.16 GLU 1098 -0.18 GLY 84

ALA 1332 0.14 MET 1099 -0.21 GLY 84

ALA 1332 0.12 SER 1100 -0.20 GLY 84

ALA 1332 0.11 LEU 1101 -0.20 GLY 84

ALA 1332 0.11 ALA 1102 -0.16 GLY 84

ALA 1332 0.11 PHE 1103 -0.13 GLY 84

VAL 231 0.10 ALA 1104 -0.13 GLY 84

ALA 1332 0.10 GLU 1105 -0.17 GLY 84

ALA 1328 0.12 VAL 1106 -0.16 GLY 84

ALA 1328 0.11 PHE 1107 -0.13 GLY 84

GLY 233 0.09 GLU 1108 -0.13 GLY 84

ALA 1328 0.10 THR 1109 -0.16 GLY 84

ALA 1328 0.11 ALA 1110 -0.14 GLY 84

ALA 235 0.19 THR 1111 -0.11 GLY 84

ALA 235 0.12 PHE 1112 -0.13 GLY 84

ALA 1347 0.12 TYR 1113 -0.14 GLY 84

ARG 196 0.14 ALA 1114 -0.12 GLY 84

ARG 196 0.12 HSD 1115 -0.13 GLY 84

ARG 196 0.12 PHE 1116 -0.13 GLY 84

ARG 196 0.14 ASP 1117 -0.12 GLU 1593

ILE 1126 0.13 VAL 1118 -0.13 GLU 1593

ILE 1126 0.16 VAL 1119 -0.15 GLU 1593

ASP 249 0.14 LYS 1120 -0.16 GLU 1593

SER 202 0.14 GLU 1121 -0.17 GLU 1593

SER 202 0.15 GLY 1122 -0.19 GLU 1593

THR 198 0.16 GLU 1123 -0.19 GLU 1593

ASP 1158 0.19 ALA 1124 -0.18 GLU 1593

PRO 1127 0.21 ASP 1125 -0.16 GLU 1593

TRP 197 0.21 ILE 1126 -0.17 GLY 1085

ASP 1125 0.21 PRO 1127 -0.11 GLU 1593

ASP 1125 0.20 ARG 1128 -0.11 ASP 1082

GLU 195 0.18 LEU 1129 -0.10 ILE 138

GLU 195 0.19 THR 1130 -0.10 ILE 138

GLU 195 0.19 ILE 1131 -0.10 ILE 138

GLU 195 0.18 ARG 1132 -0.10 ILE 138

GLU 195 0.18 VAL 1133 -0.09 ILE 138

GLU 195 0.14 CYS 1134 -0.10 ILE 138

ALA 194 0.14 ASP 1135 -0.10 ALA 1591

GLN 1534 0.10 SER 1136 -0.09 ILE 138

ASN 1513 0.11 ILE 1137 -0.09 GLY 124

ASN 1513 0.07 THR 1138 -0.12 GLY 124

GLU 1541 0.10 CYS 1139 -0.10 GLY 124

GLU 1541 0.13 ALA 1140 -0.10 ALA 1591

GLU 1541 0.11 MET 1141 -0.10 ALA 1591

GLU 1541 0.13 PHE 1142 -0.09 ALA 1591

GLU 1541 0.16 GLY 1143 -0.10 ALA 1591

GLU 1541 0.16 ALA 1144 -0.10 ALA 1591

GLU 1541 0.21 ASP 1145 -0.12 ALA 1591

GLU 1541 0.20 GLU 1146 -0.11 ALA 1591

GLU 195 0.18 LEU 1147 -0.10 ALA 1591

GLU 195 0.22 LEU 1148 -0.11 ALA 1591

GLU 195 0.24 GLU 1149 -0.12 GLU 1593

GLU 195 0.22 THR 1150 -0.11 GLU 1593

GLU 195 0.22 LEU 1151 -0.10 GLU 1593

GLU 195 0.26 GLN 1152 -0.12 GLU 1593

GLU 195 0.26 ARG 1153 -0.12 GLU 1593

GLU 195 0.23 GLU 1154 -0.11 GLU 1593

GLU 195 0.23 LEU 1155 -0.10 GLU 1593

GLU 195 0.26 ALA 1156 -0.11 GLU 1593

GLU 195 0.25 SER 1157 -0.11 GLU 1593

GLU 195 0.24 ASP 1158 -0.12 GLU 1593

GLU 195 0.21 ALA 1159 -0.11 GLU 1593

GLU 195 0.22 VAL 1160 -0.10 GLU 1593

GLU 195 0.24 ARG 1161 -0.11 GLU 1593

GLU 195 0.24 VAL 1162 -0.11 GLU 1593

GLU 195 0.24 VAL 1163 -0.11 GLU 1593

GLU 195 0.21 ARG 1164 -0.11 ALA 1591

GLU 195 0.16 ALA 1165 -0.10 ALA 137

ALA 194 0.12 PRO 1166 -0.11 ALA 137

GLU 195 0.09 CYS 1167 -0.14 GLY 124

GLU 195 0.09 VAL 1168 -0.16 ILE 138

GLU 195 0.07 GLY 1169 -0.19 GLY 124

GLU 195 0.08 LEU 1170 -0.17 GLY 124

GLU 195 0.07 CYS 1171 -0.16 GLY 124

GLU 195 0.06 ASP 1172 -0.17 GLY 124

GLU 195 0.08 HSD 1173 -0.15 GLY 124

GLU 195 0.10 ALA 1174 -0.13 ILE 138

GLU 195 0.12 PRO 1175 -0.11 ILE 138

GLU 195 0.12 ALA 1176 -0.13 ILE 138

GLU 195 0.15 VAL 1177 -0.12 ILE 138

GLU 195 0.15 GLU 1178 -0.13 ILE 138

GLU 195 0.16 VAL 1179 -0.12 ILE 138

GLU 195 0.16 GLY 1180 -0.13 ILE 138

GLY 1085 0.14 HSD 1181 -0.15 ILE 138

GLU 195 0.13 ASN 1182 -0.15 ILE 138

GLU 195 0.13 PHE 1183 -0.15 ILE 138

GLU 195 0.13 LEU 1184 -0.14 ILE 138

GLU 195 0.11 HSD 1185 -0.14 ILE 138

GLU 195 0.11 ARG 1186 -0.12 ILE 138

GLU 195 0.14 ALA 1187 -0.11 ILE 138

GLU 195 0.15 ASP 1188 -0.09 ILE 138

GLU 195 0.17 LEU 1189 -0.09 ALA 1591

GLU 195 0.16 ALA 1190 -0.09 ILE 138

GLU 195 0.15 SER 1191 -0.11 ILE 138

GLU 195 0.16 VAL 1192 -0.10 ILE 138

GLU 195 0.17 ARG 1193 -0.09 ILE 138

GLU 195 0.15 ALA 1194 -0.11 ILE 138

GLU 195 0.15 ALA 1195 -0.12 ILE 138

GLU 195 0.17 VAL 1196 -0.11 ILE 138

GLU 195 0.16 GLU 1197 -0.10 ILE 138

GLU 195 0.14 ALA 1198 -0.12 ILE 138

GLU 195 0.15 GLU 1199 -0.12 ILE 138

GLU 195 0.14 ASP 1200 -0.13 ILE 138

GLU 195 0.15 THR 1201 -0.14 ILE 138

GLY 1085 0.18 HSD 1202 -0.16 ILE 138

THR 1083 0.17 ALA 1203 -0.17 ILE 138

THR 1083 0.15 HSD 1204 -0.18 ILE 138

THR 1083 0.17 ILE 1205 -0.20 ILE 138

THR 1083 0.15 PRO 1206 -0.20 ILE 138

THR 1083 0.15 THR 1207 -0.22 ILE 138

THR 1083 0.14 TYR 1208 -0.24 ILE 138

GLY 1064 0.15 VAL 1209 -0.26 ILE 138

GLY 1064 0.18 ASP 1210 -0.26 ILE 138

GLY 1064 0.19 TYR 1211 -0.27 ILE 138

GLY 1064 0.19 ASP 1212 -0.27 ILE 138

GLY 1064 0.16 ALA 1213 -0.27 ILE 138

THR 1065 0.17 TYR 1214 -0.29 ILE 138

THR 1065 0.18 ARG 1215 -0.29 ILE 138

THR 1065 0.16 ALA 1216 -0.28 ILE 138

THR 1065 0.15 GLY 1217 -0.29 ILE 138

THR 1065 0.15 GLY 1218 -0.31 ILE 138

THR 1065 0.16 GLY 1219 -0.32 ILE 138

THR 1065 0.17 TYR 1220 -0.34 ILE 138

THR 1065 0.16 ALA 1221 -0.35 ILE 138

THR 1065 0.15 THR 1222 -0.38 ILE 138

THR 1065 0.16 LEU 1223 -0.38 ILE 138

THR 1065 0.17 GLU 1224 -0.36 ILE 138

THR 1065 0.15 ARG 1225 -0.39 ILE 138

THR 1065 0.14 LEU 1226 -0.42 ILE 138

THR 1065 0.16 ARG 1227 -0.40 ILE 138

THR 1065 0.15 SER 1228 -0.39 ILE 138

THR 1065 0.13 GLY 1229 -0.42 ILE 138

THR 1065 0.13 GLU 1230 -0.41 ILE 138

THR 1065 0.12 LEU 1231 -0.43 ILE 138

THR 1065 0.11 PRO 1232 -0.47 ILE 138

THR 1065 0.11 VAL 1233 -0.50 ILE 138

THR 1065 0.09 ASP 1234 -0.54 ILE 138

THR 1065 0.10 ASP 1235 -0.50 GLY 139

THR 1065 0.10 VAL 1236 -0.49 ILE 138

THR 1065 0.08 LEU 1237 -0.55 GLY 139

THR 1065 0.08 LYS 1238 -0.55 GLY 139

THR 1065 0.09 VAL 1239 -0.50 GLY 139

THR 1065 0.08 LEU 1240 -0.51 GLY 139

THR 1065 0.07 ASP 1241 -0.57 GLY 139

THR 1065 0.07 ASP 1242 -0.53 GLY 139

THR 1065 0.08 GLY 1243 -0.48 GLY 124

THR 1065 0.07 GLY 1244 -0.54 GLY 124

THR 1065 0.07 LEU 1245 -0.50 GLY 124

THR 1065 0.06 ARG 1246 -0.53 GLY 124

THR 1065 0.06 GLY 1247 -0.48 GLY 124

THR 1065 0.06 LEU 1248 -0.41 GLY 124

ASN 1389 0.08 GLY 1249 -0.37 GLY 124

ILE 1493 0.06 GLY 1250 -0.42 ARG 126

PHE 1483 0.07 ALA 1251 -0.55 ARG 126

PHE 1483 0.08 GLY 1252 -0.54 ARG 126

PHE 1483 0.06 PHE 1253 -0.63 GLY 124

PHE 1483 0.06 PRO 1254 -0.62 GLY 124

THR 1065 0.06 THR 1255 -0.53 GLY 124

THR 1065 0.07 GLY 1256 -0.56 GLY 139

THR 1065 0.05 ARG 1257 -0.64 GLY 139

GLY 1484 0.06 LYS 1258 -0.59 ILE 138

THR 1065 0.07 TRP 1259 -0.57 ILE 138

THR 1065 0.06 ARG 1260 -0.66 ILE 138

ARG 1263 0.07 SER 1261 -0.71 ILE 138

GLY 1484 0.06 VAL 1262 -0.61 ILE 138

SER 1261 0.07 ARG 1263 -0.61 ILE 138

SER 1261 0.07 GLY 1264 -0.71 ILE 138

GLU 1586 0.06 GLU 1265 -0.66 ILE 138

GLU 1586 0.05 PRO 1266 -0.59 THR 69

GLU 1586 0.05 GLY 1267 -0.50 THR 69

GLU 819 0.05 PRO 1268 -0.44 THR 69

ARG 1066 0.06 ARG 1269 -0.44 ILE 138

ARG 1066 0.07 LEU 1270 -0.40 ILE 138

ARG 1066 0.08 MET 1271 -0.39 ILE 138

ARG 1066 0.08 ALA 1272 -0.35 ALA 137

ARG 1066 0.09 VAL 1273 -0.33 ILE 138

ARG 1066 0.06 ASN 1274 -0.30 ALA 137

ARG 1066 0.07 GLY 1275 -0.26 ILE 138

GLU 195 0.06 ASP 1276 -0.23 ALA 137

ASP 1082 0.05 GLU 1277 -0.23 GLY 124

ASP 1276 0.05 GLY 1278 -0.19 GLY 124

GLU 1277 0.04 GLU 1279 -0.20 ARG 126

ASN 1513 0.04 PRO 1280 -0.16 GLY 124

ASN 1513 0.04 GLY 1281 -0.18 GLY 124

ASP 1082 0.05 THR 1282 -0.22 GLY 124

ASP 1082 0.07 PHE 1283 -0.22 GLY 124

ASP 1082 0.07 LYS 1284 -0.26 GLY 124

ASP 1082 0.08 ASP 1285 -0.27 GLY 124

ASP 1082 0.10 GLN 1286 -0.24 ILE 138

ASP 1082 0.09 LEU 1287 -0.24 GLY 124

GLY 1064 0.10 TYR 1288 -0.27 ILE 138

ASP 1082 0.12 LEU 1289 -0.26 ILE 138

THR 1083 0.13 ASN 1290 -0.24 ILE 138

THR 1083 0.12 THR 1291 -0.25 ILE 138

GLY 1064 0.13 ASP 1292 -0.27 ILE 138

GLY 1064 0.14 PRO 1293 -0.28 ILE 138

THR 1065 0.16 HSD 1294 -0.30 ILE 138

THR 1065 0.14 ARG 1295 -0.32 ILE 138

THR 1065 0.13 PHE 1296 -0.33 ILE 138

THR 1065 0.16 LEU 1297 -0.33 ILE 138

THR 1065 0.15 GLU 1298 -0.35 ILE 138

THR 1065 0.13 GLY 1299 -0.38 ILE 138

THR 1065 0.13 MET 1300 -0.38 ILE 138

THR 1065 0.15 LEU 1301 -0.38 ILE 138

THR 1065 0.14 ILE 1302 -0.42 ILE 138

THR 1065 0.11 GLY 1303 -0.45 ILE 138

ARG 1066 0.12 ALA 1304 -0.42 ILE 138

THR 1065 0.13 HSD 1305 -0.44 ILE 138

THR 1065 0.10 VAL 1306 -0.49 ILE 138

THR 1065 0.09 VAL 1307 -0.51 ILE 138

THR 1065 0.10 GLU 1308 -0.46 ILE 138

ARG 1066 0.11 ALA 1309 -0.42 ILE 138

PRO 1067 0.13 ALA 1310 -0.37 ILE 138

PRO 1067 0.14 ASP 1311 -0.34 ILE 138

ARG 1066 0.13 VAL 1312 -0.34 ILE 138

ARG 1066 0.12 TYR 1313 -0.30 ILE 138

ARG 1066 0.11 ILE 1314 -0.29 ILE 138

GLU 1075 0.09 TYR 1315 -0.26 ALA 137

GLU 1075 0.09 LEU 1316 -0.23 ILE 138

GLU 195 0.08 ARG 1317 -0.20 ILE 138

HSD 1115 0.12 ASP 1318 -0.18 ILE 138

GLU 195 0.11 GLU 1319 -0.17 ILE 138

ASP 1082 0.12 TYR 1320 -0.20 ILE 138

ASP 1082 0.19 PRO 1321 -0.19 ILE 138

ASP 1082 0.17 ILE 1322 -0.20 ILE 138

ASP 1082 0.15 SER 1323 -0.23 ILE 138

ASP 1082 0.18 ARG 1324 -0.22 ILE 138

ASP 1082 0.21 GLU 1325 -0.22 ILE 138

THR 1083 0.19 ILE 1326 -0.23 ILE 138

GLY 1064 0.18 LEU 1327 -0.25 ILE 138

LEU 1079 0.23 ALA 1328 -0.24 ILE 138

GLY 1064 0.24 ARG 1329 -0.24 ILE 138

GLY 1064 0.22 GLU 1330 -0.26 ILE 138

THR 1065 0.24 ILE 1331 -0.27 ILE 138

THR 1065 0.29 ALA 1332 -0.26 ILE 138

THR 1065 0.26 LYS 1333 -0.27 ILE 138

THR 1065 0.25 LEU 1334 -0.29 ILE 138

THR 1065 0.26 PRO 1335 -0.30 ILE 138

THR 1065 0.27 GLU 1336 -0.30 ILE 138

THR 1065 0.23 GLY 1337 -0.33 ILE 138

THR 1065 0.20 GLY 1338 -0.35 ILE 138

THR 1065 0.19 THR 1339 -0.35 ILE 138

ARG 1066 0.23 ARG 1340 -0.31 ILE 138

ARG 1066 0.22 ILE 1341 -0.30 ILE 138

ILE 1341 0.22 HSD 1342 -0.27 ILE 138

ARG 1066 0.14 LEU 1343 -0.25 ILE 138

GLU 1075 0.15 ARG 1344 -0.23 ILE 138

GLU 1075 0.10 ARG 1345 -0.20 ILE 138

GLU 195 0.09 GLY 1346 -0.19 ALA 137

TYR 1113 0.12 ALA 1347 -0.16 GLY 84

GLU 195 0.11 GLY 1348 -0.15 ALA 137

GLU 1521 0.10 ALA 1349 -0.15 ALA 137

GLU 1521 0.08 TYR 1350 -0.15 ALA 137

ARG 818 0.05 ILE 1351 -0.17 ALA 137

ARG 818 0.05 CYS 1352 -0.20 ALA 137

PHE 1377 0.05 GLY 1353 -0.22 ALA 137

PHE 1377 0.05 GLU 1354 -0.24 ALA 137

PRO 1376 0.08 GLU 1355 -0.30 ALA 137

ARG 818 0.06 SER 1356 -0.29 ALA 137

GLY 1367 0.07 SER 1357 -0.23 GLY 84

GLY 1367 0.07 LEU 1358 -0.26 ALA 137

ARG 1366 0.06 ILE 1359 -0.29 GLY 84

ARG 1366 0.09 GLU 1360 -0.27 GLY 84

ARG 1366 0.09 SER 1361 -0.23 GLY 84

TYR 1313 0.06 LEU 1362 -0.26 GLY 84

GLU 819 0.07 GLU 1363 -0.28 GLY 84

ARG 224 0.08 GLY 1364 -0.23 GLY 84

ARG 224 0.09 LYS 1365 -0.21 GLY 84

SER 1361 0.09 ARG 1366 -0.17 GLY 84

SER 1357 0.07 GLY 1367 -0.18 GLY 84

ARG 818 0.06 LEU 1368 -0.18 GLY 84

ARG 818 0.06 PRO 1369 -0.20 GLY 84

ARG 818 0.07 ARG 1370 -0.26 GLY 84

ALA 1589 0.08 HSD 1371 -0.34 ARG 134

ALA 1589 0.09 LYS 1372 -0.42 ARG 134

ALA 1589 0.10 PRO 1373 -0.53 THR 135

ALA 1589 0.07 PRO 1374 -0.68 THR 135

GLU 1586 0.08 PHE 1375 -0.56 ALA 137

GLU 1355 0.08 PRO 1376 -0.47 ALA 137

GLU 1487 0.08 PHE 1377 -0.54 ALA 137

GLU 1586 0.07 GLN 1378 -0.61 ALA 137

GLU 1586 0.06 VAL 1379 -0.51 GLY 84

GLU 1586 0.06 GLY 1380 -0.41 GLY 84

GLU 819 0.06 LEU 1381 -0.36 GLY 84

GLU 819 0.07 PHE 1382 -0.37 GLY 84

ARG 818 0.06 ASN 1383 -0.46 GLY 84

GLU 1586 0.05 ARG 1384 -0.47 PRO 83

GLU 1586 0.06 PRO 1385 -0.50 ALA 137

GLU 1586 0.05 THR 1386 -0.46 ALA 137

GLY 1484 0.05 LEU 1387 -0.46 ALA 137

ARG 1066 0.06 ILE 1388 -0.41 ALA 137

GLY 1249 0.08 ASN 1389 -0.39 ILE 138

ARG 1066 0.07 ASN 1390 -0.35 GLY 124

ARG 1066 0.09 ILE 1391 -0.32 ILE 138

THR 1065 0.09 GLU 1392 -0.34 GLY 124

THR 1065 0.08 THR 1393 -0.39 GLY 124

THR 1065 0.10 LEU 1394 -0.38 ILE 138

THR 1065 0.11 PHE 1395 -0.34 ILE 138

THR 1065 0.10 TRP 1396 -0.37 GLY 139

THR 1065 0.11 VAL 1397 -0.40 GLY 139

THR 1065 0.12 ARG 1398 -0.38 GLY 139

THR 1065 0.11 ASP 1399 -0.37 GLY 139

THR 1065 0.10 LEU 1400 -0.41 GLY 139

THR 1065 0.11 ILE 1401 -0.42 GLY 139

THR 1065 0.11 GLU 1402 -0.38 GLY 139

THR 1065 0.10 ARG 1403 -0.38 GLY 139

THR 1065 0.09 GLY 1404 -0.42 GLY 139

THR 1065 0.08 ALA 1405 -0.44 GLY 139

THR 1065 0.08 GLU 1406 -0.42 GLY 139

THR 1065 0.08 TRP 1407 -0.38 GLY 139

THR 1065 0.08 TRP 1408 -0.40 GLY 124

THR 1065 0.07 LYS 1409 -0.41 GLY 124

THR 1065 0.07 SER 1410 -0.37 GLY 124

THR 1065 0.07 HSD 1411 -0.35 GLY 124

THR 1065 0.06 GLY 1412 -0.35 GLY 124

THR 1065 0.06 ARG 1413 -0.32 GLY 124

THR 1065 0.05 ASN 1414 -0.30 GLY 124

THR 1065 0.05 GLY 1415 -0.35 GLY 124

THR 1065 0.05 ARG 1416 -0.39 GLY 124

THR 1065 0.06 VAL 1417 -0.42 GLY 124

THR 1065 0.07 GLY 1418 -0.41 GLY 124

THR 1065 0.07 LEU 1419 -0.37 GLY 124

THR 1065 0.07 ARG 1420 -0.35 GLY 124

THR 1065 0.07 SER 1421 -0.30 GLY 124

THR 1065 0.06 TYR 1422 -0.27 GLY 124

ASP 1082 0.05 SER 1423 -0.23 GLY 124

ASP 1082 0.05 VAL 1424 -0.20 GLY 124

ASN 1513 0.04 SER 1425 -0.17 GLY 124

GLY 1543 0.06 GLY 1426 -0.14 GLY 124

GLY 1543 0.07 ARG 1427 -0.12 GLY 124

GLY 1543 0.05 VAL 1428 -0.15 GLY 124

GLY 1543 0.05 LYS 1429 -0.15 GLY 124

THR 1083 0.05 GLU 1430 -0.17 GLY 124

THR 1083 0.05 PRO 1431 -0.18 GLY 124

THR 1083 0.06 GLY 1432 -0.21 GLY 124

ASP 1082 0.07 VAL 1433 -0.24 GLY 124

THR 1065 0.06 LYS 1434 -0.25 GLY 124

THR 1065 0.07 LEU 1435 -0.29 GLY 124

THR 1065 0.07 ALA 1436 -0.29 GLY 124

THR 1065 0.07 PRO 1437 -0.32 GLY 124

THR 1065 0.06 ALA 1438 -0.35 GLY 124

THR 1065 0.05 GLY 1439 -0.33 GLY 124

THR 1065 0.05 LEU 1440 -0.27 GLY 124

THR 1065 0.05 THR 1441 -0.23 GLY 124

THR 1065 0.04 ILE 1442 -0.20 GLY 124

THR 1065 0.04 GLN 1443 -0.18 GLY 124

THR 1065 0.05 GLU 1444 -0.21 GLY 124

THR 1065 0.05 LEU 1445 -0.22 GLY 124

THR 1065 0.04 ILE 1446 -0.19 GLY 124

THR 1065 0.05 ASP 1447 -0.18 GLY 124

THR 1065 0.05 GLU 1448 -0.20 GLY 124

THR 1065 0.05 TYR 1449 -0.21 GLY 124

THR 1065 0.05 CYS 1450 -0.19 GLY 124

GLY 1064 0.05 GLY 1451 -0.17 GLY 124

GLY 1543 0.05 GLY 1452 -0.15 GLY 124

GLY 1543 0.06 ILE 1453 -0.13 GLY 124

GLY 1543 0.06 SER 1454 -0.12 GLY 124

GLY 1543 0.07 ASP 1455 -0.10 GLY 124

GLY 1543 0.08 GLY 1456 -0.08 GLY 124

GLY 1543 0.08 HSD 1457 -0.09 GLY 124

GLY 1543 0.07 SER 1458 -0.08 GLY 124

GLY 1543 0.06 PHE 1459 -0.10 GLY 124

GLY 1543 0.07 ALA 1460 -0.08 GLY 124

GLY 1543 0.05 ALA 1461 -0.09 GLY 124

ASP 1582 0.04 TYR 1462 -0.13 GLY 124

PHE 1377 0.05 LEU 1463 -0.15 ARG 126

PHE 1377 0.05 PRO 1464 -0.20 ARG 126

PHE 1377 0.06 GLY 1465 -0.23 ARG 126

PHE 1377 0.05 GLY 1466 -0.18 ARG 126

PHE 1377 0.05 ALA 1467 -0.14 ARG 126

PHE 1377 0.06 SER 1468 -0.21 ALA 1568

PHE 1377 0.06 GLY 1469 -0.20 ARG 126

GLU 1586 0.06 GLY 1470 -0.19 ASN 1571

ASP 1582 0.06 ILE 1471 -0.11 GLY 1551

ASP 1582 0.07 LEU 1472 -0.12 GLY 1551

ASP 1582 0.08 PRO 1473 -0.10 GLY 1551

ASP 1582 0.06 ALA 1474 -0.09 GLY 124

ASP 1582 0.07 SER 1475 -0.10 GLY 1551

GLU 1586 0.07 MET 1476 -0.13 GLY 1551

GLU 1586 0.05 ASN 1477 -0.14 GLY 124

GLU 1586 0.06 ASP 1478 -0.18 GLY 124

GLU 1586 0.06 ILE 1479 -0.21 GLY 124

GLU 1586 0.05 PRO 1480 -0.27 GLY 124

GLU 1586 0.05 LEU 1481 -0.29 GLY 124

GLY 1252 0.06 ASP 1482 -0.37 GLY 124

GLY 1252 0.08 PHE 1483 -0.46 ARG 126

PHE 1377 0.07 GLY 1484 -0.48 ARG 126

PHE 1377 0.06 THR 1485 -0.35 ARG 126

GLU 1586 0.07 LEU 1486 -0.28 ARG 126

PHE 1377 0.08 GLU 1487 -0.31 ARG 148

GLU 1586 0.09 LYS 1488 -0.30 ARG 148

GLU 1586 0.10 TYR 1489 -0.27 GLN 1555

GLU 1586 0.09 GLY 1490 -0.34 GLN 1555

PHE 1377 0.07 CYS 1491 -0.26 GLN 1555

PHE 1377 0.07 PHE 1492 -0.33 ARG 126

ALA 1251 0.06 ILE 1493 -0.33 ARG 126

PHE 1377 0.06 GLY 1494 -0.36 ARG 126

THR 1065 0.05 SER 1495 -0.32 ARG 126

THR 1065 0.05 ALA 1496 -0.28 ARG 126

THR 1065 0.04 ALA 1497 -0.23 ARG 126

THR 1065 0.04 VAL 1498 -0.20 GLY 124

ASN 1513 0.04 VAL 1499 -0.16 GLY 124

GLY 1543 0.05 ILE 1500 -0.14 GLY 124

GLY 1543 0.07 LEU 1501 -0.10 GLY 124

GLY 1543 0.08 SER 1502 -0.09 GLY 124

GLY 1543 0.09 ASP 1503 -0.09 ALA 1591

GLY 1543 0.11 GLN 1504 -0.11 ALA 1591

GLY 1543 0.10 ASP 1505 -0.11 ALA 1591

GLY 1543 0.12 ASP 1506 -0.12 ALA 1591

GLY 1543 0.08 VAL 1507 -0.08 ALA 1591

GLY 1543 0.07 ARG 1508 -0.10 ALA 1591

ASN 1542 0.11 GLY 1509 -0.13 ALA 1510

MET 1141 0.06 ALA 1510 -0.13 GLY 1509

ASP 1145 0.07 ALA 1511 -0.07 ALA 1591

ASP 1145 0.13 LEU 1512 -0.12 ALA 1591

ALA 1140 0.11 ASN 1513 -0.12 ALA 1591

ASP 1145 0.06 LEU 1514 -0.07 ALA 1591

ASP 1145 0.10 MET 1515 -0.08 ALA 239

ASP 1145 0.14 LYS 1516 -0.11 ALA 1591

ASP 1135 0.08 PHE 1517 -0.08 ALA 1591

ASP 1145 0.06 PHE 1518 -0.08 ALA 137

ARG 1164 0.11 GLU 1519 -0.09 ALA 239

ARG 1164 0.13 ASP 1520 -0.10 ALA 1591

ALA 1349 0.10 GLU 1521 -0.10 GLY 84

ARG 1164 0.06 SER 1522 -0.11 ALA 238

ARG 1164 0.05 CYS 1523 -0.12 GLY 84

GLN 1152 0.07 GLY 1524 -0.10 TYR 510

GLN 1152 0.06 GLN 1525 -0.11 TYR 510

GLN 1152 0.07 CYS 1526 -0.15 ALA 1251

GLU 1149 0.10 THR 1527 -0.15 ALA 1251

GLU 1149 0.09 PRO 1528 -0.17 ALA 1251

GLU 1149 0.08 CYS 1529 -0.15 ALA 1251

ARG 1164 0.10 ARG 1530 -0.11 ALA 1251

GLU 1149 0.13 SER 1531 -0.12 GLY 1490

GLU 1149 0.12 GLY 1532 -0.15 GLY 1490

GLU 1149 0.12 THR 1533 -0.11 GLY 1490

GLU 1149 0.18 GLN 1534 -0.15 ALA 239

GLU 1149 0.17 LYS 1535 -0.13 GLY 1490

GLU 1149 0.14 ALA 1536 -0.14 GLY 1490

ASP 1145 0.18 ARG 1537 -0.12 ALA 1592

GLU 1149 0.20 MET 1538 -0.21 ASN 1542

GLU 1149 0.16 LEU 1539 -0.15 ASN 1542

ASP 1145 0.15 MET 1540 -0.14 ALA 1592

ASP 1145 0.21 GLU 1541 -0.26 ALA 1592

GLU 1146 0.17 ASN 1542 -0.32 ALA 1592

ASP 1506 0.12 GLY 1543 -0.34 ALA 1591

GLU 147 0.13 VAL 1544 -0.31 PRO 1587

GLU 147 0.14 TRP 1545 -0.14 LEU 1539

GLU 147 0.17 ASP 1546 -0.16 PRO 192

GLY 1551 0.23 THR 1547 -0.19 ILE 1577

ALA 1592 0.30 ASP 1548 -0.19 LYS 1578

GLU 147 0.21 LEU 1549 -0.19 GLY 1490

ALA 1592 0.15 LEU 1550 -0.22 GLY 1490

ASP 1548 0.28 GLY 1551 -0.30 GLY 1490

ALA 1592 0.29 GLU 1552 -0.28 GLY 1490

ALA 1592 0.17 LEU 1553 -0.24 GLY 1490

ALA 1592 0.16 ALA 1554 -0.30 GLY 1490

ALA 1592 0.23 GLN 1555 -0.34 GLY 1490

ALA 1592 0.19 CYS 1556 -0.25 GLU 1487

ALA 1592 0.12 MET 1557 -0.21 GLU 1487

ALA 1592 0.16 ARG 1558 -0.27 ALA 1251

ALA 1592 0.19 ASP 1559 -0.28 GLY 1484

ALA 1592 0.15 ALA 1560 -0.24 ALA 1251

ALA 1589 0.10 SER 1561 -0.24 ALA 1251

ALA 1589 0.09 ILE 1562 -0.24 ALA 1251

ALA 1589 0.08 CYS 1563 -0.27 ALA 1251

GLU 1586 0.09 GLY 1564 -0.30 ALA 1251

GLU 1586 0.06 LEU 1565 -0.16 GLY 1250

GLU 1586 0.07 GLY 1566 -0.17 ALA 1251

GLU 1586 0.10 GLN 1567 -0.23 ALA 1251

GLU 1586 0.09 ALA 1568 -0.21 SER 1468

GLU 1586 0.06 ALA 1569 -0.15 SER 1468

GLU 1586 0.09 SER 1570 -0.13 CYS 1491

SER 1574 0.13 ASN 1571 -0.19 GLY 1470

GLU 1586 0.06 PRO 1572 -0.10 GLY 1470

ASP 1145 0.08 VAL 1573 -0.12 GLY 1490

ASN 1571 0.13 SER 1574 -0.24 GLY 1551

GLU 1586 0.11 THR 1575 -0.17 GLY 1551

GLU 1586 0.08 VAL 1576 -0.09 THR 1547

GLU 1586 0.14 ILE 1577 -0.19 THR 1547

GLU 1586 0.18 LYS 1578 -0.19 ASP 1548

GLU 1586 0.13 TYR 1579 -0.13 ASP 1548

ASP 1582 0.16 PHE 1580 -0.11 THR 1547

ASP 1582 0.24 PRO 1581 -0.14 THR 1547

PRO 1581 0.24 ASP 1582 -0.10 ASN 280

GLU 147 0.09 LEU 1583 -0.10 ASN 280

GLU 147 0.16 PHE 1584 -0.12 ASN 280

GLU 147 0.21 PRO 1585 -0.15 GLY 1543

GLU 147 0.27 GLU 1586 -0.24 VAL 1544

GLU 147 0.33 PRO 1587 -0.31 VAL 1544

GLU 147 0.34 ARG 1588 -0.24 GLY 1543

GLU 147 0.40 ALA 1589 -0.22 ASN 280

GLU 147 0.38 VAL 1590 -0.24 GLY 1543

GLU 147 0.38 ALA 1591 -0.34 GLY 1543

GLU 147 0.46 ALA 1592 -0.34 GLY 1543

GLU 147 0.47 GLU 1593 -0.29 ASN 280

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** ***

CA distance fluctuations for 260408115242648516

--- normal mode 11 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* *