Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* 5HT2AR_elNemo_NMA *

CA distance fluctuations for 2604181804313498919

--- normal mode 10 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASN 317 0.15 ALA 78 -0.15 ASP 356

ASN 317 0.16 LEU 79 -0.11 ALA 360

ASN 317 0.17 LEU 80 -0.09 VAL 364

ASN 317 0.17 THR 81 -0.10 ASP 356

ASN 317 0.17 ALA 82 -0.10 ASP 356

ASN 317 0.18 VAL 83 -0.06 ASP 356

ASN 317 0.19 VAL 84 -0.05 GLY 359

ASN 317 0.19 ILE 85 -0.08 ASP 356

ASN 317 0.20 ILE 86 -0.07 ASP 356

ASN 317 0.22 LEU 87 -0.05 VAL 334

ASN 317 0.22 THR 88 -0.05 LEU 147

ASN 317 0.23 ILE 89 -0.08 LEU 147

ASN 317 0.25 ALA 90 -0.08 LEU 147

ASN 317 0.28 GLY 91 -0.07 LEU 147

ASN 317 0.29 ASN 92 -0.11 LEU 147

ASN 317 0.29 ILE 93 -0.14 LEU 147

ASN 317 0.34 LEU 94 -0.12 LEU 147

ASN 317 0.38 VAL 95 -0.12 LEU 147

ASN 317 0.37 ILE 96 -0.17 LEU 147

ASN 317 0.39 MET 97 -0.17 LEU 147

ASN 317 0.46 ALA 98 -0.15 LEU 147

ASN 317 0.48 VAL 99 -0.17 LEU 147

ASN 317 0.45 SER 100 -0.22 LEU 147

ASN 317 0.47 LEU 101 -0.20 LEU 147

ASN 317 0.54 GLU 102 -0.17 LEU 147

ILE 315 0.57 LYS 103 -0.18 LEU 147

ASN 317 0.67 LYS 104 -0.14 LEU 147

ASN 317 0.66 LEU 105 -0.14 LEU 147

ASN 317 0.56 GLN 106 -0.16 LEU 147

ASN 317 0.56 ASN 107 -0.14 LEU 147

ASN 317 0.43 ALA 108 -0.12 VAL 212

ASN 317 0.47 THR 109 -0.10 LEU 147

ASN 317 0.50 ASN 110 -0.12 LEU 147

ASN 317 0.41 TYR 111 -0.16 LEU 147

ASN 317 0.35 PHE 112 -0.12 LEU 147

ASN 317 0.37 LEU 113 -0.11 LEU 147

ASN 317 0.36 MET 114 -0.15 LEU 147

ASN 317 0.29 SER 115 -0.16 VAL 150

ASN 317 0.27 LEU 116 -0.11 LEU 147

ASN 317 0.29 ALA 117 -0.12 LEU 147

ASN 317 0.26 ILE 118 -0.16 LEU 147

ASN 317 0.22 ALA 119 -0.14 LEU 147

ASN 317 0.22 ASP 120 -0.09 LEU 147

ASN 317 0.22 MET 121 -0.13 LEU 147

ASN 317 0.19 LEU 122 -0.16 SER 100

ASN 317 0.18 LEU 123 -0.11 SER 100

ASN 317 0.19 GLY 124 -0.10 SER 100

ASN 317 0.18 PHE 125 -0.14 LEU 147

ASN 317 0.16 LEU 126 -0.16 SER 100

ASN 317 0.15 VAL 127 -0.13 ASP 356

ASN 317 0.16 MET 128 -0.12 ASP 356

ASN 317 0.15 PRO 129 -0.14 ASP 356

ASN 317 0.13 VAL 130 -0.15 ASP 356

ASN 317 0.14 SER 131 -0.17 ASP 356

ASN 317 0.15 MET 132 -0.16 ASP 356

ASN 317 0.13 LEU 133 -0.16 ASP 356

ASN 317 0.13 THR 134 -0.19 ASP 356

ASN 317 0.14 ILE 135 -0.21 ASP 356

ASN 317 0.14 LEU 136 -0.19 ASP 356

ASN 317 0.13 TYR 137 -0.19 ASP 356

ASN 317 0.13 GLY 138 -0.24 ASP 356

ASN 317 0.13 TYR 139 -0.24 ASP 356

ASN 317 0.13 ARG 140 -0.17 ASP 356

ASN 317 0.12 TRP 141 -0.14 ASP 356

ASN 317 0.11 PRO 142 -0.14 SER 100

ASN 317 0.10 LEU 143 -0.18 SER 100

ASN 317 0.09 PRO 144 -0.20 SER 100

ASN 317 0.10 SER 145 -0.18 SER 100

ASN 317 0.09 LYS 146 -0.21 SER 100

ASN 317 0.09 LEU 147 -0.22 SER 100

ASN 317 0.11 CYS 148 -0.17 SER 100

ASN 317 0.11 ALA 149 -0.16 SER 100

ASN 317 0.10 VAL 150 -0.20 SER 100

ASN 317 0.12 TRP 151 -0.17 SER 100

ASN 317 0.13 ILE 152 -0.13 SER 100

ASN 317 0.12 TYR 153 -0.15 SER 100

ASN 317 0.13 LEU 154 -0.16 SER 100

ASN 317 0.14 ASP 155 -0.11 ASP 356

ASN 317 0.14 VAL 156 -0.10 GLU 355

ASN 317 0.14 LEU 157 -0.12 SER 115

ASN 317 0.16 PHE 158 -0.11 SER 100

ASN 317 0.16 SER 159 -0.07 GLY 359

ASN 317 0.15 THR 160 -0.06 GLY 359

ASN 317 0.17 ALA 161 -0.08 VAL 150

ASN 317 0.19 SER 162 -0.06 LEU 147

ASN 317 0.17 ILE 163 -0.05 ILE 249

ASN 317 0.16 MET 164 -0.07 LEU 171

ASN 317 0.21 HIS 165 -0.07 VAL 150

ASN 317 0.21 LEU 166 -0.05 VAL 328

ASN 317 0.17 CYS 167 -0.06 TYR 254

ASN 317 0.20 ALA 168 -0.07 ILE 202

ASN 317 0.26 ILE 169 -0.06 PHE 383

ASN 317 0.21 SER 170 -0.06 ILE 202

ASN 317 0.18 LEU 171 -0.09 ILE 202

ASN 317 0.25 ASP 172 -0.08 ILE 202

ASN 317 0.29 ARG 173 -0.06 ILE 202

ASN 317 0.18 TYR 174 -0.07 ILE 202

ASN 317 0.20 VAL 175 -0.09 ILE 202

ASN 317 0.27 ALA 176 -0.06 GLY 205

ASN 107 0.23 ILE 177 -0.05 GLY 205

LYS 104 0.18 GLN 178 -0.08 ILE 202

ILE 315 0.22 ASN 179 -0.09 GLY 205

ILE 315 0.38 PRO 180 -0.08 GLY 205

ILE 315 0.37 ILE 181 -0.10 GLY 205

ILE 315 0.29 HIS 182 -0.12 ALA 198

ILE 315 0.31 HIS 183 -0.10 GLY 205

ILE 315 0.38 SER 184 -0.10 VAL 212

ILE 315 0.32 ARG 185 -0.12 VAL 212

ILE 315 0.28 PHE 186 -0.13 VAL 212

ILE 315 0.33 ASN 187 -0.12 VAL 212

ILE 315 0.34 SER 188 -0.13 VAL 212

ASN 317 0.34 ARG 189 -0.15 VAL 212

ASN 317 0.28 THR 190 -0.17 VAL 212

ASN 317 0.27 LYS 191 -0.15 VAL 212

ASN 317 0.30 ALA 192 -0.14 VAL 212

ASN 317 0.27 PHE 193 -0.18 VAL 212

ASN 317 0.22 LEU 194 -0.17 VAL 212

ASN 317 0.22 LYS 195 -0.14 VAL 212

ASN 317 0.23 ILE 196 -0.16 VAL 212

ASN 317 0.20 ILE 197 -0.20 MET 208

ASN 317 0.16 ALA 198 -0.15 MET 208

ASN 317 0.17 VAL 199 -0.12 MET 208

ASN 317 0.17 TRP 200 -0.16 MET 208

ASN 317 0.14 THR 201 -0.21 MET 208

ASN 317 0.12 ILE 202 -0.11 HIS 182

ASN 317 0.13 SER 203 -0.09 SER 207

ASN 317 0.12 VAL 204 -0.19 THR 201

ASN 317 0.10 GLY 205 -0.20 THR 201

ASN 317 0.10 ILE 206 -0.13 THR 201

ASN 317 0.11 SER 207 -0.14 THR 201

ASN 317 0.09 MET 208 -0.21 THR 201

ASN 317 0.10 PRO 209 -0.15 ILE 197

ASN 317 0.10 ILE 210 -0.15 ILE 197

ASN 317 0.09 PRO 211 -0.18 ILE 197

ASN 317 0.08 VAL 212 -0.20 ILE 197

PHE 234 0.12 PHE 213 -0.16 ILE 197

PHE 234 0.11 GLY 214 -0.15 ILE 197

ASN 317 0.09 LEU 215 -0.18 SER 100

ASN 233 0.09 GLN 216 -0.17 SER 100

ASN 317 0.09 ASP 217 -0.15 SER 100

ASN 317 0.10 ASP 218 -0.14 SER 100

PRO 338 0.11 SER 219 -0.11 ILE 197

PRO 338 0.11 LYS 220 -0.11 ILE 197

ASN 317 0.11 VAL 221 -0.11 SER 100

ASN 363 0.12 PHE 222 -0.11 SER 100

LEU 362 0.16 LYS 223 -0.08 ASN 354

ASN 363 0.16 GLU 224 -0.08 SER 100

ASN 363 0.13 GLY 225 -0.10 ASN 354

ASN 363 0.15 SER 226 -0.15 GLU 355

VAL 366 0.14 CYS 227 -0.13 GLU 355

VAL 366 0.15 LEU 228 -0.16 GLU 355

PHE 339 0.13 LEU 229 -0.12 GLU 355

PHE 339 0.15 ALA 230 -0.09 THR 201

PHE 340 0.12 ASP 231 -0.10 THR 201

VAL 334 0.10 ASP 232 -0.09 THR 201

PHE 213 0.09 ASN 233 -0.10 THR 201

PHE 213 0.12 PHE 234 -0.11 THR 201

ASN 317 0.10 VAL 235 -0.09 THR 201

ASN 317 0.09 LEU 236 -0.07 THR 201

PHE 213 0.09 ILE 237 -0.09 THR 201

ASN 317 0.10 GLY 238 -0.08 THR 201

ASN 317 0.10 SER 239 -0.05 THR 201

ASN 317 0.08 PHE 240 -0.05 PHE 340

ASN 317 0.09 VAL 241 -0.06 LYS 259

ASN 317 0.11 SER 242 -0.04 ILE 249

ASN 317 0.11 PHE 243 -0.05 PHE 244

ASN 317 0.08 PHE 244 -0.05 GLN 319

ASN 317 0.08 ILE 245 -0.06 LYS 259

ASN 317 0.11 PRO 246 -0.06 ILE 249

CYS 353 0.10 LEU 247 -0.06 GLN 319

CYS 353 0.11 THR 248 -0.09 GLN 319

CYS 353 0.09 ILE 249 -0.08 ILE 202

CYS 353 0.11 MET 250 -0.07 GLN 319

CYS 353 0.15 VAL 251 -0.12 GLN 319

CYS 353 0.13 ILE 252 -0.11 GLN 319

CYS 353 0.12 THR 253 -0.09 ILE 202

CYS 353 0.14 TYR 254 -0.11 GLN 319

CYS 353 0.15 PHE 255 -0.17 ILE 315

LYS 104 0.14 LEU 256 -0.12 ILE 315

LYS 104 0.17 THR 257 -0.07 ILE 202

LYS 104 0.19 ILE 258 -0.18 ILE 315

LYS 104 0.19 LYS 259 -0.23 ILE 315

LYS 104 0.21 SER 260 -0.10 ILE 315

LYS 104 0.27 LEU 261 -0.11 ILE 315

LYS 104 0.29 GLN 262 -0.30 ILE 315

LYS 104 0.66 ILE 315 -0.30 GLN 262

LYS 385 0.73 SER 316 -0.16 GLN 262

ASN 384 0.75 ASN 317 -0.10 GLN 262

ASN 384 0.47 GLU 318 -0.12 LYS 259

LYS 385 0.47 GLN 319 -0.16 CYS 322

ASN 384 0.58 LYS 320 -0.05 PHE 255

ASN 384 0.40 ALA 321 -0.02 LYS 320

ASN 384 0.29 CYS 322 -0.16 GLN 319

LYS 385 0.29 LYS 323 -0.16 GLY 326

PHE 383 0.24 VAL 324 -0.03 ALA 176

LEU 105 0.17 LEU 325 -0.10 LYS 323

CYS 353 0.18 GLY 326 -0.16 LYS 323

CYS 353 0.19 ILE 327 -0.12 LYS 323

CYS 353 0.17 VAL 328 -0.05 LYS 323

CYS 353 0.17 PHE 329 -0.07 LYS 323

CYS 353 0.21 PHE 330 -0.10 GLN 319

LEU 361 0.18 LEU 331 -0.06 PHE 330

CYS 353 0.15 PHE 332 -0.05 SER 373

ILE 341 0.18 VAL 333 -0.05 GLN 319

CYS 353 0.21 VAL 334 -0.06 SER 372

LEU 331 0.16 MET 335 -0.05 VAL 334

ASN 317 0.13 TRP 336 -0.05 LEU 80

VAL 333 0.16 CYS 337 -0.05 LEU 80

VAL 334 0.19 PRO 338 -0.07 LEU 80

VAL 334 0.15 PHE 339 -0.07 LEU 80

ALA 230 0.15 PHE 340 -0.07 ILE 341

VAL 334 0.18 ILE 341 -0.07 PHE 340

VAL 334 0.19 THR 342 -0.08 ALA 78

ALA 230 0.15 ASN 343 -0.08 ALA 78

VAL 334 0.13 ILE 344 -0.06 ALA 78

PHE 330 0.17 MET 345 -0.08 ALA 78

VAL 334 0.15 ALA 346 -0.09 SER 131

VAL 334 0.12 VAL 347 -0.08 VAL 156

PHE 330 0.13 ILE 348 -0.07 GLY 138

PHE 330 0.17 CYS 349 -0.09 GLY 138

PHE 330 0.15 LYS 350 -0.11 GLY 138

PHE 330 0.21 CYS 353 -0.14 GLY 138

VAL 334 0.19 ASN 354 -0.18 GLY 138

VAL 334 0.16 GLU 355 -0.20 TYR 139

VAL 334 0.16 ASP 356 -0.24 GLY 138

VAL 334 0.20 VAL 357 -0.15 GLY 138

VAL 334 0.19 ILE 358 -0.13 ILE 135

GLU 224 0.15 GLY 359 -0.16 ILE 135

VAL 334 0.15 ALA 360 -0.15 ALA 78

VAL 334 0.20 LEU 361 -0.11 ALA 78

LYS 223 0.16 LEU 362 -0.10 ALA 78

GLU 224 0.16 ASN 363 -0.11 ALA 78

PHE 383 0.15 VAL 364 -0.10 ALA 78

LEU 331 0.16 PHE 365 -0.08 LEU 80

LEU 228 0.15 VAL 366 -0.06 LEU 80

ASN 317 0.15 TRP 367 -0.07 LEU 80

VAL 379 0.17 ILE 368 -0.07 LEU 80

ASN 317 0.16 GLY 369 -0.04 LEU 80

ASN 317 0.17 TYR 370 -0.03 MET 121

ASN 317 0.18 LEU 371 -0.05 VAL 334

ASN 317 0.19 SER 372 -0.06 VAL 334

ASN 317 0.20 SER 373 -0.05 PHE 330

ASN 317 0.21 ALA 374 -0.05 PHE 330

ASN 317 0.22 VAL 375 -0.05 PHE 330

ASN 317 0.25 ASN 376 -0.05 PHE 330

ASN 317 0.32 PRO 377 -0.05 LEU 147

ASN 317 0.31 LEU 378 -0.03 LEU 147

ASN 317 0.29 VAL 379 -0.02 ILE 169

ASN 317 0.38 TYR 380 -0.04 LEU 147

ASN 317 0.50 THR 381 -0.06 LEU 113

ASN 317 0.45 LEU 382 -0.04 THR 109

ASN 317 0.51 PHE 383 -0.09 THR 109

ASN 317 0.75 ASN 384 -0.09 THR 109

SER 316 0.73 LYS 385 -0.08 THR 109

SER 316 0.69 THR 386 -0.09 LEU 147

ASN 317 0.57 TYR 387 -0.09 LEU 147

SER 316 0.50 ARG 388 -0.06 LEU 147

SER 316 0.54 SER 389 -0.08 LEU 147

SER 316 0.49 ALA 390 -0.11 LEU 147

SER 316 0.40 PHE 391 -0.08 LEU 147

SER 316 0.39 SER 392 -0.07 LEU 147

SER 316 0.41 ARG 393 -0.11 LEU 147

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: december 26th, 2025.

Should you encounter any unexpected behaviour, please let us know. elNémo has been hacked on november 27th. It has been moved away and runs again. **Still some additional cleaning from time to time** Sorry for the inconvenience.

*** 5HT2AR_elNemo_NMA ***

CA distance fluctuations for 2604181804313498919

--- normal mode 10 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been hacked on november 27th.
It has been moved away and runs again.
Still some additional cleaning from time to time
Sorry for the inconvenience.

* 5HT2AR_elNemo_NMA *