Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* HYDROLASE (ACID PROTEINASE) 27-NOV-90 3APP *

CA distance fluctuations for 2605131121222426564

--- normal mode 7 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASN 241 0.11 ALA 1 -0.09 GLY 99

ASN 241 0.12 ALA 2 -0.10 GLY 99

ASN 241 0.10 SER 3 -0.10 ALA 97

ASN 241 0.10 GLY 4 -0.13 VAL 95

ASP 77 0.09 VAL 5 -0.10 SER 250

ASN 241 0.10 ALA 6 -0.10 VAL 92

ASP 77 0.13 THR 7 -0.10 VAL 92

ASP 77 0.16 ASN 8 -0.06 VAL 21

ASP 77 0.19 THR 9 -0.06 PRO 20

ASP 77 0.26 PRO 10 -0.06 ILE 293

ASP 77 0.26 THR 11 -0.08 ILE 293

ASP 77 0.32 ALA 12 -0.09 ILE 293

ASP 77 0.42 ASN 13 -0.09 SER 291

ASP 77 0.38 ASP 14 -0.08 ILE 293

ASP 77 0.44 GLU 15 -0.10 ILE 293

ASP 77 0.31 GLU 16 -0.08 THR 216

ASP 77 0.22 TYR 17 -0.05 ILE 293

ASN 241 0.15 ILE 18 -0.06 GLY 35

ASN 241 0.14 THR 19 -0.06 THR 9

ASN 241 0.15 PRO 20 -0.07 PRO 162

ASN 241 0.18 VAL 21 -0.08 THR 7

ASN 241 0.19 THR 22 -0.09 THR 7

ASN 241 0.23 ILE 23 -0.07 THR 7

ASN 241 0.23 GLY 24 -0.08 THR 7

ASN 241 0.19 GLY 25 -0.09 THR 7

ASN 241 0.20 THR 26 -0.07 PRO 162

ASN 241 0.18 THR 27 -0.08 PRO 162

ASN 241 0.22 LEU 28 -0.04 GLN 188

ASN 241 0.19 ASN 29 -0.06 GLY 35

ASN 241 0.24 LEU 30 -0.07 GLY 35

ASN 241 0.24 ASN 31 -0.08 GLY 35

ASN 241 0.21 PHE 32 -0.07 GLY 35

GLY 243 0.25 ASP 33 -0.09 GLY 35

GLY 243 0.22 THR 34 -0.08 ASP 115

GLY 243 0.28 GLY 35 -0.13 ASP 115

GLY 243 0.33 SER 36 -0.12 ASP 115

SER 240 0.31 ALA 37 -0.08 ASP 115

ASN 241 0.37 ASP 38 -0.06 PHE 112

ASN 241 0.35 LEU 39 -0.08 THR 139

ASN 241 0.41 TRP 40 -0.05 THR 139

ASN 241 0.39 VAL 41 -0.05 GLN 188

ASN 241 0.41 PHE 42 -0.05 GLN 188

ASN 241 0.39 SER 43 -0.04 THR 143

ASN 241 0.37 THR 44 -0.03 THR 143

ASN 241 0.43 GLU 45 -0.04 THR 143

ASN 241 0.48 LEU 46 -0.04 GLN 188

ASN 241 0.48 PRO 47 -0.04 GLN 188

ASN 241 0.40 ALA 48 -0.04 GLN 188

ASP 279 0.44 SER 49 -0.06 GLN 188

ASN 241 0.49 GLN 50 -0.07 GLN 188

ASN 241 0.39 GLN 51 -0.06 GLN 188

GLY 278 0.35 SER 52 -0.07 GLN 188

GLY 278 0.30 GLY 53 -0.08 GLN 188

GLY 278 0.28 HIS 54 -0.07 GLN 188

ASN 241 0.25 SER 55 -0.05 GLN 188

ASN 241 0.31 VAL 56 -0.04 GLN 188

ASN 241 0.31 TYR 57 -0.04 THR 7

ASN 241 0.31 ASN 58 -0.04 THR 7

ASN 241 0.33 PRO 59 -0.05 SER 147

ASN 241 0.31 SER 60 -0.05 SER 3

ASN 241 0.27 ALA 61 -0.05 GLY 94

ASN 241 0.26 THR 62 -0.06 GLY 94

ASN 241 0.29 GLY 63 -0.07 THR 96

ASN 241 0.30 LYS 64 -0.09 SER 147

ASN 241 0.34 GLU 65 -0.09 SER 147

ASN 241 0.36 LEU 66 -0.10 SER 147

ASN 241 0.38 SER 67 -0.10 SER 147

ASN 241 0.42 GLY 68 -0.09 SER 146

ASN 241 0.42 TYR 69 -0.10 SER 146

ASN 241 0.48 THR 70 -0.08 SER 146

SER 240 0.51 TRP 71 -0.07 THR 143

SER 240 0.59 SER 72 -0.05 GLN 137

SER 240 0.65 ILE 73 -0.10 ILE 129

SER 240 0.81 SER 74 -0.11 ILE 129

GLY 243 0.93 TYR 75 -0.18 GLN 188

GLY 243 1.11 GLY 76 -0.21 GLN 188

GLY 243 1.43 ASP 77 -0.18 GLN 188

SER 240 1.21 GLY 78 -0.14 GLN 188

ASN 241 0.97 SER 79 -0.13 GLN 188

ASN 241 0.81 SER 80 -0.10 GLN 188

ASN 241 0.67 ALA 81 -0.08 ILE 129

ASN 241 0.60 SER 82 -0.05 THR 143

ASN 241 0.52 GLY 83 -0.06 THR 143

ASN 241 0.46 ASN 84 -0.07 SER 146

ASN 241 0.40 VAL 85 -0.07 SER 146

ASN 241 0.35 PHE 86 -0.08 SER 147

ASN 241 0.30 THR 87 -0.09 SER 147

ASN 241 0.26 ASP 88 -0.10 SER 89

ASN 241 0.22 SER 89 -0.10 ASP 88

ASN 241 0.22 VAL 90 -0.07 THR 7

ASN 241 0.18 THR 91 -0.08 THR 7

ASN 241 0.16 VAL 92 -0.10 THR 7

ASN 241 0.12 GLY 93 -0.09 THR 7

ASN 241 0.12 GLY 94 -0.08 PRO 162

ASN 241 0.14 VAL 95 -0.13 GLY 4

ASN 241 0.17 THR 96 -0.09 ASP 88

ASN 241 0.20 ALA 97 -0.10 SER 3

ASN 241 0.21 HIS 98 -0.10 ALA 2

ASN 241 0.25 GLY 99 -0.11 SER 147

ASN 241 0.26 GLN 100 -0.08 SER 147

ASN 241 0.31 ALA 101 -0.10 THR 143

ASN 241 0.34 VAL 102 -0.06 THR 143

ASN 241 0.41 GLN 103 -0.07 THR 143

ASN 241 0.43 ALA 104 -0.06 THR 143

ASN 241 0.50 ALA 105 -0.05 THR 143

ASN 241 0.53 GLN 106 -0.05 THR 143

ASN 241 0.63 GLN 107 -0.05 GLN 188

ASN 241 0.69 ILE 108 -0.08 GLN 188

ASN 241 0.86 SER 109 -0.10 GLN 188

ASN 241 0.88 ALA 110 -0.11 GLN 188

GLY 278 0.84 GLN 111 -0.13 GLN 188

ASN 241 0.64 PHE 112 -0.12 GLN 188

GLY 278 0.62 GLN 113 -0.11 GLN 188

GLY 278 0.70 GLN 114 -0.12 GLN 188

GLY 278 0.55 ASP 115 -0.13 GLN 188

GLY 278 0.37 THR 116 -0.11 GLY 35

GLY 278 0.27 ASN 117 -0.10 GLY 35

GLY 278 0.29 ASN 118 -0.10 GLY 35

ASN 241 0.32 ASP 119 -0.07 GLN 188

ASN 241 0.37 GLY 120 -0.08 GLN 188

ASN 241 0.34 LEU 121 -0.08 GLY 189

ASN 241 0.28 LEU 122 -0.07 GLY 123

ASN 241 0.28 GLY 123 -0.08 ASP 115

GLY 243 0.22 LEU 124 -0.06 ASP 115

SER 240 0.23 ALA 125 -0.09 ASP 115

SER 240 0.23 PHE 126 -0.08 ASP 115

SER 240 0.27 SER 127 -0.09 SER 312

SER 240 0.28 SER 128 -0.13 TYR 75

SER 240 0.34 ILE 129 -0.15 TYR 75

SER 240 0.36 ASN 130 -0.11 TYR 75

SER 240 0.46 THR 131 -0.08 ILE 73

SER 240 0.43 VAL 132 -0.08 THR 143

SER 240 0.45 GLN 133 -0.09 SER 146

SER 240 0.42 PRO 134 -0.10 SER 146

SER 240 0.37 GLN 135 -0.13 SER 146

SER 240 0.36 SER 136 -0.10 SER 146

SER 240 0.32 GLN 137 -0.10 SER 146

SER 240 0.27 THR 138 -0.15 ASP 142

ASN 241 0.25 THR 139 -0.08 LEU 39

ASN 241 0.22 PHE 140 -0.06 PHE 153

ASN 241 0.19 PHE 141 -0.08 THR 138

SER 240 0.20 ASP 142 -0.15 THR 138

ASN 241 0.21 THR 143 -0.11 GLN 135

ASN 241 0.17 VAL 144 -0.09 PHE 169

ASN 241 0.16 LYS 145 -0.10 GLN 135

ASN 241 0.15 SER 146 -0.13 GLN 135

ASN 241 0.14 SER 147 -0.11 GLY 99

ASN 241 0.13 LEU 148 -0.09 GLY 99

ASN 241 0.10 ALA 149 -0.09 SER 178

ASN 241 0.10 GLN 150 -0.09 LEU 179

SER 240 0.12 PRO 151 -0.09 THR 138

ASN 241 0.12 LEU 152 -0.08 THR 138

ASN 241 0.11 PHE 153 -0.07 THR 138

ASP 77 0.11 ALA 154 -0.09 SER 250

ASP 77 0.15 VAL 155 -0.09 SER 250

ASP 77 0.19 ALA 156 -0.12 SER 250

ASP 77 0.24 LEU 157 -0.10 SER 250

ASP 77 0.26 LYS 158 -0.14 ASN 273

ASP 77 0.31 HIS 159 -0.17 GLY 275

ASP 77 0.29 GLN 160 -0.16 GLY 275

ASP 77 0.24 GLN 161 -0.14 GLY 275

ASP 77 0.20 PRO 162 -0.11 SER 250

ASP 77 0.18 GLY 163 -0.12 SER 250

ASP 77 0.15 VAL 164 -0.11 SER 250

ASP 77 0.12 TYR 165 -0.08 SER 250

ASP 77 0.09 ASP 166 -0.10 SER 250

ASN 241 0.11 PHE 167 -0.08 ALA 97

ASN 241 0.10 GLY 168 -0.09 VAL 144

ASN 241 0.08 PHE 169 -0.10 SER 250

ASP 77 0.10 ILE 170 -0.12 SER 250

ASP 77 0.12 ASP 171 -0.14 SER 250

ASP 77 0.13 SER 172 -0.16 SER 250

ASP 77 0.14 SER 173 -0.19 SER 250

ASP 77 0.16 LYS 174 -0.18 SER 250

ASP 77 0.17 TYR 175 -0.19 ASN 252

ASP 77 0.16 THR 176 -0.22 ASN 252

ASP 77 0.14 GLY 177 -0.20 ASN 252

ASP 77 0.13 SER 178 -0.16 ASN 252

ASP 77 0.12 LEU 179 -0.13 ASN 252

ASP 77 0.12 THR 180 -0.11 ASN 252

ASP 77 0.09 TYR 181 -0.09 ALA 265

GLY 243 0.07 THR 182 -0.07 ALA 265

SER 240 0.09 GLY 183 -0.06 ILE 260

SER 240 0.12 VAL 184 -0.06 ASP 115

SER 240 0.13 ASP 185 -0.08 ASP 115

SER 240 0.17 ASN 186 -0.10 GLY 76

ILE 293 0.18 SER 187 -0.17 GLY 76

ILE 293 0.26 GLN 188 -0.21 GLY 76

SER 240 0.22 GLY 189 -0.16 GLY 76

SER 240 0.20 PHE 190 -0.11 ASP 115

SER 240 0.16 TRP 191 -0.08 ASP 115

SER 240 0.14 SER 192 -0.08 ASP 115

SER 240 0.10 PHE 193 -0.06 ASP 115

GLY 76 0.09 ASN 194 -0.04 ASP 115

GLY 76 0.16 VAL 195 -0.03 GLY 183

GLY 76 0.15 ASP 196 -0.04 GLY 183

GLY 76 0.21 SER 197 -0.04 TYR 181

GLY 76 0.28 TYR 198 -0.07 SER 259

GLY 76 0.32 THR 199 -0.12 THR 264

GLY 76 0.40 ALA 200 -0.11 GLY 177

GLY 76 0.39 GLY 201 -0.15 GLY 177

GLY 76 0.35 SER 202 -0.14 GLY 177

GLY 76 0.34 GLN 203 -0.11 GLY 177

GLY 76 0.30 SER 204 -0.09 GLY 177

GLY 76 0.26 GLY 205 -0.06 GLY 177

GLY 76 0.20 ASP 206 -0.03 GLY 292

GLY 76 0.18 GLY 207 -0.03 GLY 292

GLY 76 0.16 PHE 208 -0.04 ASP 115

SER 74 0.13 SER 209 -0.06 ASP 115

GLY 76 0.17 GLY 210 -0.07 ASP 115

GLY 243 0.15 ILE 211 -0.08 ASP 115

GLY 76 0.16 ALA 212 -0.05 ASP 115

TYR 75 0.20 ASP 213 -0.06 ASP 115

TYR 75 0.21 THR 214 -0.05 ASN 117

TYR 75 0.27 GLY 215 -0.07 ASN 117

TYR 75 0.47 THR 216 -0.08 GLU 16

ASP 77 0.52 THR 217 -0.09 ILE 293

ASP 77 0.63 LEU 218 -0.08 ASN 290

GLY 76 0.57 LEU 219 -0.07 SER 305

GLY 76 0.66 LEU 220 -0.08 ASN 290

GLY 76 0.54 LEU 221 -0.06 SER 305

GLY 76 0.48 ASP 222 -0.05 ASN 13

GLY 76 0.57 ASP 223 -0.06 ALA 323

GLY 76 0.45 SER 224 -0.06 ALA 323

GLY 76 0.47 VAL 225 -0.07 ALA 323

GLY 76 0.60 VAL 226 -0.08 ALA 323

GLY 76 0.55 SER 227 -0.08 ALA 323

GLY 76 0.47 GLN 228 -0.09 THR 176

GLY 76 0.51 TYR 229 -0.11 ALA 323

GLY 76 0.57 TYR 230 -0.11 ALA 323

GLY 76 0.50 SER 231 -0.11 ALA 323

ASP 77 0.47 GLN 232 -0.13 THR 176

ASP 77 0.54 VAL 233 -0.15 ALA 323

ASP 77 0.53 SER 234 -0.15 ALA 323

ASP 77 0.59 GLY 235 -0.14 ALA 323

ASP 77 0.66 ALA 236 -0.13 ALA 323

ASP 77 0.73 GLN 237 -0.11 ALA 323

ASP 77 0.87 GLN 238 -0.08 ALA 323

GLY 78 0.98 ASP 239 -0.07 ALA 323

GLY 78 1.21 SER 240 -0.05 SER 231

GLY 78 1.15 ASN 241 -0.05 SER 231

ASP 77 1.12 ALA 242 -0.05 GLN 160

ASP 77 1.43 GLY 243 -0.08 ASN 13

ASP 77 1.14 GLY 244 -0.06 ASN 13

ASP 77 0.88 TYR 245 -0.09 ALA 323

ASP 77 0.82 VAL 246 -0.12 ALA 323

ASP 77 0.69 PHE 247 -0.15 ALA 323

ASP 77 0.61 ASP 248 -0.17 ALA 323

ASP 77 0.58 CYS 249 -0.20 ALA 323

ASP 77 0.51 SER 250 -0.24 ALA 323

ASP 77 0.53 THR 251 -0.21 ALA 323

ASP 77 0.48 ASN 252 -0.23 ALA 323

ASP 77 0.49 LEU 253 -0.19 ALA 323

ASP 77 0.44 PRO 254 -0.18 THR 176

ASP 77 0.40 ASP 255 -0.18 PRO 321

GLY 76 0.39 PHE 256 -0.15 PRO 321

GLY 76 0.31 SER 257 -0.11 GLY 177

GLY 76 0.26 VAL 258 -0.07 GLY 177

GLY 76 0.20 SER 259 -0.09 THR 199

GLY 76 0.16 ILE 260 -0.07 TYR 181

GLY 76 0.11 SER 261 -0.07 ASN 252

GLY 76 0.14 GLY 262 -0.09 SER 202

GLY 76 0.17 TYR 263 -0.10 ASN 252

GLY 76 0.22 THR 264 -0.12 GLY 201

ASP 77 0.24 ALA 265 -0.11 PHE 319

ASP 77 0.30 THR 266 -0.17 PRO 321

ASP 77 0.36 VAL 267 -0.20 PRO 321

ASP 77 0.39 PRO 268 -0.23 PRO 321

ASP 77 0.45 GLY 269 -0.22 ALA 323

ASP 77 0.45 SER 270 -0.24 ALA 323

ASP 77 0.46 LEU 271 -0.19 ALA 323

ASP 77 0.54 ILE 272 -0.15 ALA 323

ASP 77 0.56 ASN 273 -0.17 ALA 323

ASP 77 0.62 TYR 274 -0.13 HIS 159

ASP 77 0.61 GLY 275 -0.17 HIS 159

ASP 77 0.67 PRO 276 -0.13 HIS 159

ASP 77 0.85 SER 277 -0.08 GLN 160

GLN 111 0.84 GLY 278 -0.07 GLN 160

GLY 78 0.79 ASP 279 -0.07 ALA 323

GLY 78 0.70 GLY 280 -0.11 ALA 323

ASP 77 0.63 SER 281 -0.14 ALA 323

ASP 77 0.71 THR 282 -0.14 ALA 323

ASP 77 0.72 CYS 283 -0.14 ALA 323

ASP 77 0.83 LEU 284 -0.10 ALA 323

ASP 77 0.75 GLY 285 -0.11 ALA 323

ASP 77 0.67 GLY 286 -0.09 ALA 323

GLY 76 0.66 ILE 287 -0.08 ALA 323

GLY 76 0.85 GLN 288 -0.07 ASN 13

GLY 76 0.86 SER 289 -0.08 ASN 13

GLY 76 0.74 ASN 290 -0.09 ASN 13

GLY 76 0.75 SER 291 -0.09 ASN 13

SER 74 0.43 GLY 292 -0.08 ALA 12

THR 131 0.37 ILE 293 -0.12 ASP 115

THR 131 0.28 GLY 294 -0.10 ASP 115

THR 131 0.23 PHE 295 -0.09 ASP 115

GLY 76 0.32 SER 296 -0.07 GLY 299

GLY 76 0.38 ILE 297 -0.08 GLY 299

GLY 76 0.34 PHE 298 -0.06 GLY 299

GLY 76 0.39 GLY 299 -0.08 ILE 297

ASP 77 0.37 ASP 300 -0.06 ILE 293

ASP 77 0.45 ILE 301 -0.07 LYS 304

GLY 76 0.35 PHE 302 -0.06 ASN 273

ASP 77 0.28 LEU 303 -0.07 ASN 273

ASP 77 0.30 LYS 304 -0.12 ASN 273

ASP 77 0.28 SER 305 -0.15 LEU 271

ASP 77 0.23 GLN 306 -0.17 TYR 307

ASP 77 0.18 TYR 307 -0.17 GLN 306

ASP 77 0.15 VAL 308 -0.09 SER 250

ASP 77 0.10 VAL 309 -0.09 SER 250

GLY 243 0.11 PHE 310 -0.06 SER 250

SER 240 0.11 ASP 311 -0.08 THR 138

SER 240 0.13 SER 312 -0.10 THR 138

SER 240 0.11 ASP 313 -0.10 THR 138

SER 240 0.11 GLY 314 -0.09 SER 128

SER 240 0.12 PRO 315 -0.09 SER 128

SER 240 0.10 GLN 316 -0.06 ALA 265

GLY 243 0.09 LEU 317 -0.07 ALA 265

ASP 77 0.11 GLY 318 -0.10 ALA 265

ASP 77 0.15 PHE 319 -0.11 ALA 265

ASP 77 0.17 ALA 320 -0.15 PRO 268

ASP 77 0.20 PRO 321 -0.23 PRO 268

ASP 77 0.21 GLN 322 -0.21 PRO 268

ASP 77 0.19 ALA 323 -0.24 SER 270

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.

Should you encounter any unexpected behaviour, please let us know. elNémo has been relocated. **Some cleaning from time to time** Sorry for the inconvenience.

*** HYDROLASE (ACID PROTEINASE) 27-NOV-90 3APP ***

CA distance fluctuations for 2605131121222426564

--- normal mode 7 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* HYDROLASE (ACID PROTEINASE) 27-NOV-90 3APP *