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* CELL ADHESION/IMMUNE SYSTEM 21-SEP-11 3VI3 *

CA strain for 260522123717486593

--- normal mode 10 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
PHE 1 ASN 2 0.0002

ASN 2 LEU 3 0.0001

LEU 3 ASP 4 0.0002

ASP 4 ALA 5 -0.0001

ALA 5 GLU 6 -0.0001

GLU 6 ALA 7 0.0003

ALA 7 PRO 8 0.0001

PRO 8 ALA 9 -0.0001

ALA 9 VAL 10 -0.0002

VAL 10 LEU 11 0.0000

LEU 11 SER 12 0.0002

SER 12 GLY 13 0.0002

GLY 13 PRO 14 -0.0004

PRO 14 PRO 15 0.0004

PRO 15 GLY 16 -0.0031

GLY 16 SER 17 0.0001

SER 17 PHE 18 -0.0003

PHE 18 PHE 19 -0.0001

PHE 19 GLY 20 0.0003

GLY 20 PHE 21 0.0003

PHE 21 SER 22 -0.0002

SER 22 VAL 23 -0.0000

VAL 23 GLU 24 0.0001

GLU 24 PHE 25 -0.0002

PHE 25 TYR 26 -0.0003

TYR 26 ARG 27 0.0001

ARG 27 PRO 28 -0.0000

PRO 28 GLY 29 -0.0003

GLY 29 THR 30 0.0001

THR 30 ASP 31 -0.0014

ASP 31 GLY 32 0.0004

GLY 32 VAL 33 0.0001

VAL 33 SER 34 0.0003

SER 34 VAL 35 -0.0002

VAL 35 LEU 36 -0.0002

LEU 36 VAL 37 -0.0002

VAL 37 GLY 38 0.0002

GLY 38 ALA 39 -0.0002

ALA 39 PRO 40 0.0001

PRO 40 LYS 41 -0.0004

LYS 41 ALA 42 0.0001

ALA 42 ASN 43 -0.0002

ASN 43 THR 44 0.0001

THR 44 SER 45 -0.0001

SER 45 GLN 46 -0.0002

GLN 46 PRO 47 -0.0001

PRO 47 GLY 48 -0.0002

GLY 48 VAL 49 -0.0002

VAL 49 LEU 50 0.0005

LEU 50 GLN 51 -0.0001

GLN 51 GLY 52 -0.0003

GLY 52 GLY 53 -0.0001

GLY 53 ALA 54 0.0001

ALA 54 VAL 55 -0.0002

VAL 55 TYR 56 -0.0002

TYR 56 LEU 57 0.0000

LEU 57 CYS 58 0.0001

CYS 58 PRO 59 -0.0001

PRO 59 TRP 60 -0.0001

TRP 60 GLY 61 0.0009

GLY 61 ALA 62 0.0000

ALA 62 SER 63 0.0001

SER 63 PRO 64 0.0001

PRO 64 THR 65 -0.0002

THR 65 GLN 66 -0.0000

GLN 66 CYS 67 0.0000

CYS 67 THR 68 -0.0003

THR 68 PRO 69 0.0001

PRO 69 ILE 70 -0.0004

ILE 70 GLU 71 0.0004

GLU 71 PHE 72 -0.0001

PHE 72 ASP 73 0.0001

ASP 73 SER 74 -0.0001

SER 74 LYS 75 -0.0000

LYS 75 GLY 76 -0.0010

GLY 76 SER 77 0.0002

SER 77 ARG 78 -0.0002

ARG 78 LEU 79 0.0002

LEU 79 LEU 80 -0.0005

LEU 80 GLU 81 0.0004

GLU 81 SER 82 -0.0002

SER 82 SER 83 0.0001

SER 83 LEU 84 -0.0000

LEU 84 SER 85 -0.0005

SER 85 SER 86 -0.0002

SER 86 SER 87 -0.0000

SER 87 GLU 88 0.0001

GLU 88 GLY 89 -0.0004

GLY 89 GLU 90 0.0005

GLU 90 GLU 91 -0.0013

GLU 91 PRO 92 0.0000

PRO 92 VAL 93 0.0001

VAL 93 GLU 94 -0.0003

GLU 94 TYR 95 0.0002

TYR 95 LYS 96 0.0002

LYS 96 SER 97 0.0001

SER 97 LEU 98 0.0001

LEU 98 GLN 99 0.0001

GLN 99 TRP 100 0.0001

TRP 100 PHE 101 0.0000

PHE 101 GLY 102 0.0000

GLY 102 ALA 103 0.0000

ALA 103 THR 104 -0.0002

THR 104 VAL 105 0.0002

VAL 105 ARG 106 0.0009

ARG 106 ALA 107 0.0002

ALA 107 HIS 108 -0.0005

HIS 108 GLY 109 -0.0000

GLY 109 SER 110 0.0001

SER 110 SER 111 -0.0002

SER 111 ILE 112 0.0002

ILE 112 LEU 113 -0.0000

LEU 113 ALA 114 0.0003

ALA 114 CYS 115 0.0000

CYS 115 ALA 116 -0.0002

ALA 116 PRO 117 0.0001

PRO 117 LEU 118 -0.0000

LEU 118 TYR 119 0.0001

TYR 119 SER 120 -0.0002

SER 120 TRP 121 -0.0006

TRP 121 ARG 122 0.0002

ARG 122 THR 123 0.0000

THR 123 GLU 124 -0.0001

GLU 124 LYS 125 0.0000

LYS 125 GLU 126 0.0001

GLU 126 PRO 127 -0.0002

PRO 127 LEU 128 0.0000

LEU 128 SER 129 0.0001

SER 129 ASP 130 -0.0003

ASP 130 PRO 131 0.0004

PRO 131 VAL 132 0.0003

VAL 132 GLY 133 0.0003

GLY 133 THR 134 0.0001

THR 134 CYS 135 -0.0002

CYS 135 TYR 136 -0.0015

TYR 136 LEU 137 0.0001

LEU 137 SER 138 -0.0003

SER 138 THR 139 -0.0000

THR 139 ASP 140 0.0000

ASP 140 ASN 141 0.0000

ASN 141 PHE 142 -0.0004

PHE 142 THR 143 -0.0002

THR 143 ARG 144 -0.0001

ARG 144 ILE 145 -0.0004

ILE 145 LEU 146 -0.0001

LEU 146 GLU 147 0.0003

GLU 147 TYR 148 -0.0000

TYR 148 ALA 149 0.0006

ALA 149 PRO 150 -0.0001

PRO 150 CYS 151 0.0007

CYS 151 ARG 152 0.0000

ARG 152 SER 153 0.0003

SER 153 ASP 154 -0.0003

ASP 154 PHE 155 -0.0001

PHE 155 SER 156 0.0000

SER 156 TRP 157 0.0003

TRP 157 ALA 158 -0.0004

ALA 158 ALA 159 0.0001

ALA 159 GLY 160 -0.0001

GLY 160 GLN 161 0.0001

GLN 161 GLY 162 -0.0001

GLY 162 TYR 163 0.0001

TYR 163 CYS 164 -0.0000

CYS 164 GLN 165 0.0001

GLN 165 GLY 166 -0.0009

GLY 166 GLY 167 -0.0003

GLY 167 PHE 168 -0.0004

PHE 168 SER 169 0.0001

SER 169 ALA 170 0.0001

ALA 170 GLU 171 -0.0001

GLU 171 PHE 172 -0.0004

PHE 172 THR 173 -0.0001

THR 173 LYS 174 0.0002

LYS 174 THR 175 0.0001

THR 175 GLY 176 0.0002

GLY 176 ARG 177 -0.0001

ARG 177 VAL 178 0.0003

VAL 178 VAL 179 -0.0000

VAL 179 LEU 180 0.0002

LEU 180 GLY 181 -0.0009

GLY 181 GLY 182 0.0002

GLY 182 PRO 183 -0.0004

PRO 183 GLY 184 -0.0001

GLY 184 SER 185 -0.0001

SER 185 TYR 186 -0.0001

TYR 186 PHE 187 -0.0001

PHE 187 TRP 188 0.0000

TRP 188 GLN 189 0.0000

GLN 189 GLY 190 -0.0001

GLY 190 GLN 191 -0.0003

GLN 191 ILE 192 0.0002

ILE 192 LEU 193 -0.0003

LEU 193 SER 194 -0.0001

SER 194 ALA 195 -0.0000

ALA 195 THR 196 -0.0004

THR 196 GLN 197 0.0001

GLN 197 GLU 198 -0.0003

GLU 198 GLN 199 -0.0001

GLN 199 ILE 200 0.0002

ILE 200 ALA 201 -0.0002

ALA 201 GLU 202 0.0003

GLU 202 SER 203 0.0004

SER 203 TYR 204 -0.0001

TYR 204 TYR 205 -0.0002

TYR 205 PRO 206 -0.0004

PRO 206 GLU 207 -0.0001

GLU 207 TYR 208 -0.0001

TYR 208 LEU 209 -0.0000

LEU 209 ILE 210 -0.0003

ILE 210 ASN 211 0.0001

ASN 211 LEU 212 -0.0002

LEU 212 VAL 213 0.0001

VAL 213 GLN 214 -0.0001

GLN 214 GLY 215 -0.0001

GLY 215 GLN 216 0.0002

GLN 216 LEU 217 -0.0005

LEU 217 GLN 218 0.0002

GLN 218 THR 219 -0.0005

THR 219 ARG 220 0.0002

ARG 220 GLN 221 0.0001

GLN 221 ALA 222 0.0005

ALA 222 SER 223 -0.0003

SER 223 SER 224 0.0004

SER 224 ILE 225 -0.0004

ILE 225 TYR 226 0.0008

TYR 226 ASP 227 0.0001

ASP 227 ASP 228 0.0003

ASP 228 SER 229 0.0000

SER 229 TYR 230 -0.0003

TYR 230 LEU 231 0.0003

LEU 231 GLY 232 -0.0002

GLY 232 TYR 233 0.0002

TYR 233 SER 234 -0.0002

SER 234 VAL 235 -0.0001

VAL 235 ALA 236 -0.0000

ALA 236 VAL 237 0.0000

VAL 237 GLY 238 0.0001

GLY 238 GLU 239 -0.0000

GLU 239 PHE 240 0.0000

PHE 240 SER 241 0.0006

SER 241 GLY 242 -0.0003

GLY 242 ASP 243 0.0000

ASP 243 ASP 244 -0.0003

ASP 244 THR 245 0.0001

THR 245 GLU 246 0.0002

GLU 246 ASP 247 -0.0001

ASP 247 PHE 248 0.0003

PHE 248 VAL 249 -0.0002

VAL 249 ALA 250 0.0001

ALA 250 GLY 251 0.0001

GLY 251 VAL 252 0.0002

VAL 252 PRO 253 -0.0003

PRO 253 LYS 254 -0.0000

LYS 254 GLY 255 0.0002

GLY 255 ASN 256 -0.0003

ASN 256 LEU 257 -0.0000

LEU 257 THR 258 0.0003

THR 258 TYR 259 0.0001

TYR 259 GLY 260 0.0002

GLY 260 TYR 261 0.0000

TYR 261 VAL 262 -0.0001

VAL 262 THR 263 -0.0001

THR 263 ILE 264 -0.0000

ILE 264 LEU 265 -0.0002

LEU 265 ASN 266 0.0002

ASN 266 GLY 267 -0.0001

GLY 267 SER 268 -0.0000

SER 268 ASP 269 0.0004

ASP 269 ILE 270 0.0001

ILE 270 ARG 271 -0.0017

ARG 271 SER 272 -0.0003

SER 272 LEU 273 -0.0001

LEU 273 TYR 274 -0.0002

TYR 274 ASN 275 -0.0000

ASN 275 PHE 276 0.0003

PHE 276 SER 277 0.0001

SER 277 GLY 278 0.0001

GLY 278 GLU 279 -0.0002

GLU 279 GLN 280 0.0001

GLN 280 MET 281 0.0001

MET 281 ALA 282 0.0000

ALA 282 SER 283 0.0001

SER 283 TYR 284 -0.0002

TYR 284 PHE 285 0.0002

PHE 285 GLY 286 -0.0002

GLY 286 TYR 287 -0.0002

TYR 287 ALA 288 -0.0002

ALA 288 VAL 289 0.0000

VAL 289 ALA 290 -0.0004

ALA 290 ALA 291 0.0003

ALA 291 THR 292 -0.0003

THR 292 ASP 293 0.0003

ASP 293 VAL 294 -0.0002

VAL 294 ASN 295 0.0001

ASN 295 GLY 296 -0.0000

GLY 296 ASP 297 0.0001

ASP 297 GLY 298 0.0002

GLY 298 LEU 299 0.0003

LEU 299 ASP 300 -0.0003

ASP 300 ASP 301 -0.0002

ASP 301 LEU 302 -0.0002

LEU 302 LEU 303 -0.0003

LEU 303 VAL 304 0.0001

VAL 304 GLY 305 0.0005

GLY 305 ALA 306 0.0004

ALA 306 PRO 307 -0.0001

PRO 307 LEU 308 -0.0003

LEU 308 LEU 309 0.0003

LEU 309 MET 310 -0.0001

MET 310 ASP 311 -0.0003

ASP 311 ARG 312 0.0004

ARG 312 THR 313 0.0002

THR 313 PRO 314 0.0001

PRO 314 ASP 315 0.0003

ASP 315 GLY 316 -0.0048

GLY 316 ARG 317 -0.0000

ARG 317 PRO 318 0.0001

PRO 318 GLN 319 -0.0002

GLN 319 GLU 320 0.0002

GLU 320 VAL 321 -0.0000

VAL 321 GLY 322 -0.0002

GLY 322 ARG 323 0.0002

ARG 323 VAL 324 -0.0000

VAL 324 TYR 325 0.0003

TYR 325 VAL 326 -0.0000

VAL 326 TYR 327 0.0004

TYR 327 LEU 328 -0.0003

LEU 328 GLN 329 0.0004

GLN 329 HIS 330 -0.0003

HIS 330 PRO 331 -0.0012

PRO 331 ALA 332 0.0000

ALA 332 GLY 333 -0.0002

GLY 333 ILE 334 -0.0002

ILE 334 GLU 335 0.0003

GLU 335 PRO 336 0.0000

PRO 336 THR 337 0.0003

THR 337 PRO 338 -0.0001

PRO 338 THR 339 -0.0002

THR 339 LEU 340 -0.0000

LEU 340 THR 341 0.0002

THR 341 LEU 342 -0.0001

LEU 342 THR 343 0.0002

THR 343 GLY 344 -0.0001

GLY 344 HIS 345 0.0003

HIS 345 ASP 346 0.0003

ASP 346 GLU 347 -0.0002

GLU 347 PHE 348 0.0001

PHE 348 GLY 349 0.0004

GLY 349 ARG 350 0.0001

ARG 350 PHE 351 -0.0001

PHE 351 GLY 352 0.0001

GLY 352 SER 353 0.0000

SER 353 SER 354 0.0002

SER 354 LEU 355 -0.0003

LEU 355 THR 356 0.0001

THR 356 PRO 357 0.0000

PRO 357 LEU 358 -0.0003

LEU 358 GLY 359 -0.0002

GLY 359 ASP 360 0.0002

ASP 360 LEU 361 0.0008

LEU 361 ASP 362 -0.0003

ASP 362 GLN 363 -0.0001

GLN 363 ASP 364 -0.0000

ASP 364 GLY 365 0.0001

GLY 365 TYR 366 -0.0004

TYR 366 ASN 367 0.0001

ASN 367 ASP 368 0.0001

ASP 368 VAL 369 0.0002

VAL 369 ALA 370 -0.0005

ALA 370 ILE 371 0.0001

ILE 371 GLY 372 0.0005

GLY 372 ALA 373 0.0001

ALA 373 PRO 374 0.0000

PRO 374 PHE 375 -0.0000

PHE 375 GLY 376 -0.0022

GLY 376 GLY 377 -0.0001

GLY 377 GLU 378 -0.0000

GLU 378 THR 379 -0.0001

THR 379 GLN 380 0.0002

GLN 380 GLN 381 0.0005

GLN 381 GLY 382 -0.0003

GLY 382 VAL 383 0.0001

VAL 383 VAL 384 0.0001

VAL 384 PHE 385 0.0001

PHE 385 VAL 386 0.0000

VAL 386 PHE 387 -0.0001

PHE 387 PRO 388 -0.0001

PRO 388 GLY 389 0.0003

GLY 389 GLY 390 0.0003

GLY 390 PRO 391 -0.0007

PRO 391 GLY 392 0.0001

GLY 392 GLY 393 0.0001

GLY 393 LEU 394 -0.0002

LEU 394 GLY 395 0.0003

GLY 395 SER 396 -0.0000

SER 396 LYS 397 -0.0003

LYS 397 PRO 398 0.0002

PRO 398 SER 399 0.0001

SER 399 GLN 400 0.0002

GLN 400 VAL 401 -0.0000

VAL 401 LEU 402 -0.0002

LEU 402 GLN 403 0.0003

GLN 403 PRO 404 -0.0003

PRO 404 LEU 405 -0.0004

LEU 405 TRP 406 -0.0009

TRP 406 ALA 407 -0.0000

ALA 407 ALA 408 -0.0005

ALA 408 SER 409 0.0004

SER 409 HIS 410 -0.0001

HIS 410 THR 411 0.0001

THR 411 PRO 412 -0.0004

PRO 412 ASP 413 -0.0001

ASP 413 PHE 414 0.0000

PHE 414 PHE 415 0.0002

PHE 415 GLY 416 -0.0004

GLY 416 SER 417 -0.0001

SER 417 ALA 418 -0.0001

ALA 418 LEU 419 0.0003

LEU 419 ARG 420 -0.0002

ARG 420 GLY 421 0.0015

GLY 421 GLY 422 0.0001

GLY 422 ARG 423 -0.0003

ARG 423 ASP 424 0.0001

ASP 424 LEU 425 -0.0001

LEU 425 ASP 426 -0.0004

ASP 426 GLY 427 0.0002

GLY 427 ASN 428 0.0003

ASN 428 GLY 429 0.0003

GLY 429 TYR 430 0.0001

TYR 430 PRO 431 0.0001

PRO 431 ASP 432 -0.0006

ASP 432 LEU 433 0.0002

LEU 433 ILE 434 -0.0003

ILE 434 VAL 435 -0.0000

VAL 435 GLY 436 0.0022

GLY 436 SER 437 -0.0002

SER 437 PHE 438 0.0002

PHE 438 GLY 439 -0.0003

GLY 439 VAL 440 -0.0002

VAL 440 ASP 441 -0.0001

ASP 441 LYS 442 0.0003

LYS 442 ALA 443 -0.0003

ALA 443 VAL 444 0.0001

VAL 444 VAL 445 -0.0000

VAL 445 TYR 446 -0.0001

TYR 446 ARG 447 0.0002

ARG 447 GLY 448 0.0002

GLY 448 ARG 449 0.0001

ARG 449 PRO 450 -0.0003

PRO 450 ILE 451 -0.0011

ILE 451 VAL 452 0.0001

VAL 452 SER 453 0.0000

SER 453 ALA 454 0.0002

ALA 454 SER 455 0.0001

SER 455 ALA 456 0.0002

ALA 456 SER 457 -0.0004

SER 457 LEU 458 0.0002

LEU 458 THR 459 -0.0001

THR 459 ILE 460 0.0001

ILE 460 PHE 461 -0.0000

PHE 461 PRO 462 0.0004

PRO 462 ALA 463 -0.0001

ALA 463 MET 464 -0.0003

MET 464 PHE 465 0.0001

PHE 465 ASN 466 0.0001

ASN 466 PRO 467 0.0004

PRO 467 GLU 468 0.0001

GLU 468 GLU 469 0.0000

GLU 469 ARG 470 -0.0001

ARG 470 SER 471 -0.0000

SER 471 CYS 472 0.0001

CYS 472 SER 473 -0.0000

SER 473 LEU 474 0.0001

LEU 474 GLU 475 0.0002

GLU 475 GLY 476 0.0002

GLY 476 ASN 477 -0.0001

ASN 477 PRO 478 -0.0003

PRO 478 VAL 479 -0.0000

VAL 479 ALA 480 0.0001

ALA 480 CYS 481 0.0002

CYS 481 ILE 482 -0.0001

ILE 482 ASN 483 0.0001

ASN 483 LEU 484 0.0006

LEU 484 SER 485 -0.0000

SER 485 PHE 486 -0.0000

PHE 486 CYS 487 -0.0001

CYS 487 LEU 488 0.0004

LEU 488 ASN 489 -0.0000

ASN 489 ALA 490 0.0002

ALA 490 SER 491 0.0002

SER 491 GLY 492 -0.0002

GLY 492 LYS 493 0.0002

LYS 493 HIS 494 -0.0004

HIS 494 VAL 495 -0.0002

VAL 495 ALA 496 0.0031

ALA 496 ASP 497 -0.0001

ASP 497 SER 498 0.0003

SER 498 ILE 499 -0.0002

ILE 499 GLY 500 0.0004

GLY 500 PHE 501 -0.0000

PHE 501 THR 502 0.0004

THR 502 VAL 503 -0.0002

VAL 503 GLU 504 0.0000

GLU 504 LEU 505 0.0000

LEU 505 GLN 506 -0.0003

GLN 506 LEU 507 0.0003

LEU 507 ASP 508 -0.0002

ASP 508 TRP 509 -0.0002

TRP 509 GLN 510 0.0001

GLN 510 LYS 511 -0.0001

LYS 511 GLN 512 -0.0001

GLN 512 LYS 513 -0.0002

LYS 513 GLY 514 0.0000

GLY 514 GLY 515 0.0000

GLY 515 VAL 516 0.0001

VAL 516 ARG 517 -0.0001

ARG 517 ARG 518 -0.0002

ARG 518 ALA 519 0.0004

ALA 519 LEU 520 -0.0002

LEU 520 PHE 521 0.0002

PHE 521 LEU 522 0.0003

LEU 522 ALA 523 -0.0000

ALA 523 SER 524 0.0001

SER 524 ARG 525 0.0001

ARG 525 GLN 526 -0.0012

GLN 526 ALA 527 -0.0001

ALA 527 THR 528 -0.0001

THR 528 LEU 529 0.0002

LEU 529 THR 530 0.0000

THR 530 GLN 531 -0.0003

GLN 531 THR 532 0.0003

THR 532 LEU 533 0.0004

LEU 533 LEU 534 -0.0001

LEU 534 ILE 535 -0.0001

ILE 535 GLN 536 0.0002

GLN 536 ASN 537 0.0002

ASN 537 GLY 538 0.0001

GLY 538 ALA 539 0.0001

ALA 539 ARG 540 -0.0001

ARG 540 GLU 541 -0.0015

GLU 541 ASP 542 -0.0001

ASP 542 CYS 543 -0.0001

CYS 543 ARG 544 -0.0001

ARG 544 GLU 545 0.0000

GLU 545 MET 546 0.0001

MET 546 LYS 547 0.0001

LYS 547 ILE 548 0.0001

ILE 548 TYR 549 0.0001

TYR 549 LEU 550 0.0000

LEU 550 ARG 551 0.0001

ARG 551 ASN 552 0.0001

ASN 552 GLU 553 -0.0000

GLU 553 SER 554 -0.0005

SER 554 GLU 555 0.0001

GLU 555 PHE 556 -0.0001

PHE 556 ARG 557 0.0000

ARG 557 ASP 558 0.0002

ASP 558 LYS 559 -0.0001

LYS 559 LEU 560 -0.0000

LEU 560 SER 561 -0.0000

SER 561 PRO 562 -0.0000

PRO 562 ILE 563 -0.0002

ILE 563 HIS 564 -0.0001

HIS 564 ILE 565 -0.0001

ILE 565 ALA 566 0.0004

ALA 566 LEU 567 0.0000

LEU 567 ASN 568 -0.0001

ASN 568 PHE 569 0.0003

PHE 569 SER 570 -0.0002

SER 570 LEU 571 -0.0109

LEU 571 ASP 572 0.0003

ASP 572 PRO 573 -0.0003

PRO 573 GLN 574 -0.0002

GLN 574 ALA 575 0.0000

ALA 575 PRO 576 0.0001

PRO 576 VAL 577 -0.0002

VAL 577 ASP 578 0.0002

ASP 578 SER 579 -0.0001

SER 579 HIS 580 0.0003

HIS 580 GLY 581 -0.0005

GLY 581 LEU 582 -0.0003

LEU 582 ARG 583 -0.0001

ARG 583 PRO 584 0.0001

PRO 584 ALA 585 -0.0001

ALA 585 LEU 586 -0.0038

LEU 586 HIS 587 0.0002

HIS 587 TYR 588 -0.0001

TYR 588 GLN 589 0.0002

GLN 589 SER 590 -0.0000

SER 590 LYS 591 0.0002

LYS 591 SER 592 0.0001

SER 592 ARG 593 -0.0003

ARG 593 ILE 594 0.0002

ILE 594 GLU 595 0.0001

GLU 595 ASP 596 0.0001

ASP 596 LYS 597 -0.0002

LYS 597 ALA 598 0.0001

ALA 598 GLN 599 0.0002

GLN 599 ILE 600 -0.0000

ILE 600 LEU 601 -0.0001

LEU 601 ARG 6 0.0235

ARG 6 CYS 7 -0.0003

CYS 7 LEU 8 -0.0000

LEU 8 LYS 9 0.0002

LYS 9 ALA 10 0.0004

ALA 10 ASN 11 0.0001

ASN 11 ALA 12 -0.0001

ALA 12 LYS 13 0.0003

LYS 13 SER 14 -0.0001

SER 14 CYS 15 -0.0002

CYS 15 GLY 16 -0.0002

GLY 16 GLU 17 0.0000

GLU 17 CYS 18 -0.0003

CYS 18 ILE 19 -0.0003

ILE 19 GLN 20 -0.0002

GLN 20 ALA 21 -0.0005

ALA 21 GLY 22 0.0002

GLY 22 PRO 23 0.0002

PRO 23 ASN 24 0.0001

ASN 24 CYS 25 0.0002

CYS 25 GLY 26 0.0003

GLY 26 TRP 27 -0.0002

TRP 27 CYS 28 0.0001

CYS 28 THR 29 -0.0001

THR 29 ARG 43 0.0000

ARG 43 CYS 44 0.0000

CYS 44 ASP 45 0.0004

ASP 45 ASP 46 -0.0004

ASP 46 LEU 47 0.0001

LEU 47 GLU 48 0.0001

GLU 48 ALA 49 0.0001

ALA 49 LEU 50 0.0001

LEU 50 LYS 51 0.0001

LYS 51 LYS 52 -0.0002

LYS 52 LYS 53 0.0000

LYS 53 GLY 54 0.0001

GLY 54 CYS 55 -0.0003

CYS 55 PRO 56 0.0003

PRO 56 PRO 57 -0.0003

PRO 57 ASP 58 -0.0005

ASP 58 ASP 59 -0.0004

ASP 59 ILE 60 0.0002

ILE 60 GLU 61 -0.0004

GLU 61 ASN 62 0.0001

ASN 62 PRO 63 -0.0003

PRO 63 ARG 64 0.0003

ARG 64 GLY 65 0.0003

GLY 65 SER 66 -0.0002

SER 66 LYS 67 0.0000

LYS 67 ASP 68 -0.0001

ASP 68 ILE 69 0.0001

ILE 69 LYS 70 0.0002

LYS 70 LYS 71 -0.0002

LYS 71 ASN 72 -0.0000

ASN 72 LYS 73 0.0043

LYS 73 ASN 74 -0.0004

ASN 74 VAL 75 -0.0003

VAL 75 THR 76 -0.0004

THR 76 ASN 77 -0.0003

ASN 77 ARG 78 0.0003

ARG 78 SER 79 -0.0001

SER 79 LYS 80 0.0002

LYS 80 GLY 81 -0.0001

GLY 81 THR 82 -0.0003

THR 82 ALA 83 0.0002

ALA 83 GLU 84 -0.0001

GLU 84 LYS 85 0.0003

LYS 85 LEU 86 -0.0003

LEU 86 LYS 87 -0.0001

LYS 87 PRO 88 0.0101

PRO 88 GLU 89 -0.0000

GLU 89 ASP 90 -0.0000

ASP 90 ILE 91 -0.0001

ILE 91 HIS 92 0.0001

HIS 92 GLN 93 -0.0002

GLN 93 ILE 94 0.0002

ILE 94 GLN 95 0.0002

GLN 95 PRO 96 -0.0001

PRO 96 GLN 97 -0.0001

GLN 97 GLN 98 0.0003

GLN 98 LEU 99 -0.0000

LEU 99 VAL 100 -0.0001

VAL 100 LEU 101 -0.0000

LEU 101 ARG 102 -0.0002

ARG 102 LEU 103 0.0008

LEU 103 ARG 104 0.0001

ARG 104 SER 105 -0.0001

SER 105 GLY 106 -0.0001

GLY 106 GLU 107 0.0002

GLU 107 PRO 108 0.0001

PRO 108 GLN 109 0.0001

GLN 109 THR 110 -0.0001

THR 110 PHE 111 -0.0002

PHE 111 THR 112 -0.0000

THR 112 LEU 113 0.0001

LEU 113 LYS 114 -0.0002

LYS 114 PHE 115 0.0000

PHE 115 LYS 116 -0.0002

LYS 116 ARG 117 -0.0001

ARG 117 ALA 118 0.0074

ALA 118 GLU 119 0.0001

GLU 119 ASP 120 0.0004

ASP 120 TYR 121 -0.0001

TYR 121 PRO 122 -0.0002

PRO 122 ILE 123 0.0005

ILE 123 ASP 124 -0.0002

ASP 124 LEU 125 0.0001

LEU 125 TYR 126 -0.0001

TYR 126 TYR 127 -0.0003

TYR 127 LEU 128 -0.0001

LEU 128 MET 129 -0.0002

MET 129 ASP 130 -0.0001

ASP 130 LEU 131 -0.0002

LEU 131 SER 132 0.0001

SER 132 TYR 133 0.0060

TYR 133 SER 134 0.0002

SER 134 MET 135 0.0000

MET 135 LYS 136 -0.0002

LYS 136 ASP 137 -0.0000

ASP 137 ASP 138 0.0002

ASP 138 LEU 139 -0.0001

LEU 139 GLU 140 0.0002

GLU 140 ASN 141 -0.0001

ASN 141 VAL 142 -0.0003

VAL 142 LYS 143 -0.0001

LYS 143 SER 144 -0.0001

SER 144 LEU 145 -0.0002

LEU 145 GLY 146 -0.0000

GLY 146 THR 147 0.0001

THR 147 ASP 148 -0.0019

ASP 148 LEU 149 -0.0001

LEU 149 MET 150 -0.0002

MET 150 ASN 151 -0.0001

ASN 151 GLU 152 -0.0004

GLU 152 MET 153 -0.0002

MET 153 ARG 154 0.0001

ARG 154 ARG 155 -0.0002

ARG 155 ILE 156 -0.0004

ILE 156 THR 157 -0.0001

THR 157 SER 158 0.0002

SER 158 ASP 159 0.0000

ASP 159 PHE 160 -0.0003

PHE 160 ARG 161 0.0004

ARG 161 ILE 162 -0.0003

ILE 162 GLY 163 -0.0113

GLY 163 PHE 164 0.0001

PHE 164 GLY 165 -0.0000

GLY 165 SER 166 0.0002

SER 166 PHE 167 0.0003

PHE 167 VAL 168 -0.0000

VAL 168 GLU 169 -0.0000

GLU 169 LYS 170 0.0004

LYS 170 THR 171 -0.0001

THR 171 VAL 172 0.0002

VAL 172 MET 173 -0.0001

MET 173 PRO 174 0.0003

PRO 174 TYR 175 -0.0001

TYR 175 ILE 176 0.0003

ILE 176 SER 177 -0.0001

SER 177 THR 178 -0.0014

THR 178 THR 179 -0.0000

THR 179 PRO 180 0.0005

PRO 180 ALA 181 0.0004

ALA 181 LYS 182 -0.0002

LYS 182 LEU 183 -0.0000

LEU 183 ARG 184 0.0000

ARG 184 ASN 185 0.0004

ASN 185 PRO 186 0.0002

PRO 186 CYS 187 0.0005

CYS 187 THR 188 -0.0004

THR 188 SER 189 0.0000

SER 189 GLU 190 -0.0001

GLU 190 GLN 191 -0.0002

GLN 191 ASN 192 0.0003

ASN 192 CYS 193 0.0012

CYS 193 THR 194 0.0001

THR 194 THR 195 0.0002

THR 195 PRO 196 -0.0003

PRO 196 PHE 197 0.0000

PHE 197 SER 198 -0.0005

SER 198 TYR 199 0.0005

TYR 199 LYS 200 -0.0003

LYS 200 ASN 201 -0.0001

ASN 201 VAL 202 0.0002

VAL 202 LEU 203 -0.0003

LEU 203 SER 204 0.0002

SER 204 LEU 205 0.0001

LEU 205 THR 206 -0.0000

THR 206 ASN 207 -0.0000

ASN 207 LYS 208 0.0016

LYS 208 GLY 209 -0.0003

GLY 209 GLU 210 -0.0001

GLU 210 VAL 211 -0.0002

VAL 211 PHE 212 -0.0002

PHE 212 ASN 213 -0.0003

ASN 213 GLU 214 0.0002

GLU 214 LEU 215 -0.0004

LEU 215 VAL 216 -0.0004

VAL 216 GLY 217 0.0001

GLY 217 LYS 218 0.0003

LYS 218 GLN 219 -0.0002

GLN 219 ARG 220 0.0000

ARG 220 ILE 221 -0.0001

ILE 221 SER 222 -0.0002

SER 222 GLY 223 0.0017

GLY 223 ASN 224 -0.0001

ASN 224 LEU 225 -0.0001

LEU 225 ASP 226 -0.0001

ASP 226 SER 227 -0.0001

SER 227 PRO 228 -0.0000

PRO 228 GLU 229 -0.0003

GLU 229 GLY 230 0.0000

GLY 230 GLY 231 0.0004

GLY 231 PHE 232 0.0001

PHE 232 ASP 233 0.0001

ASP 233 ALA 234 0.0000

ALA 234 ILE 235 -0.0000

ILE 235 MET 236 0.0001

MET 236 GLN 237 0.0006

GLN 237 VAL 238 0.0026

VAL 238 ALA 239 0.0001

ALA 239 VAL 240 0.0002

VAL 240 CYS 241 -0.0001

CYS 241 GLY 242 -0.0004

GLY 242 SER 243 -0.0002

SER 243 LEU 244 -0.0000

LEU 244 ILE 245 0.0002

ILE 245 GLY 246 0.0004

GLY 246 TRP 247 0.0002

TRP 247 ARG 248 -0.0002

ARG 248 ASN 249 -0.0001

ASN 249 VAL 250 -0.0001

VAL 250 THR 251 0.0001

THR 251 ARG 252 -0.0004

ARG 252 LEU 253 -0.0013

LEU 253 LEU 254 -0.0001

LEU 254 VAL 255 -0.0000

VAL 255 PHE 256 -0.0003

PHE 256 SER 257 0.0001

SER 257 THR 258 -0.0002

THR 258 ASP 259 -0.0003

ASP 259 ALA 260 0.0001

ALA 260 GLY 261 0.0001

GLY 261 PHE 262 -0.0003

PHE 262 HIS 263 0.0003

HIS 263 PHE 264 -0.0002

PHE 264 ALA 265 0.0001

ALA 265 GLY 266 0.0000

GLY 266 ASP 267 -0.0001

ASP 267 GLY 268 -0.0037

GLY 268 LYS 269 -0.0001

LYS 269 LEU 270 -0.0002

LEU 270 GLY 271 -0.0002

GLY 271 GLY 272 0.0002

GLY 272 ILE 273 0.0001

ILE 273 VAL 274 -0.0004

VAL 274 LEU 275 0.0001

LEU 275 PRO 276 0.0004

PRO 276 ASN 277 -0.0001

ASN 277 ASP 278 0.0001

ASP 278 GLY 279 0.0000

GLY 279 GLN 280 0.0004

GLN 280 CYS 281 -0.0003

CYS 281 HIS 282 0.0001

HIS 282 LEU 283 -0.0050

LEU 283 GLU 284 0.0000

GLU 284 ASN 285 -0.0002

ASN 285 ASN 286 0.0002

ASN 286 MET 287 0.0002

MET 287 TYR 288 -0.0002

TYR 288 THR 289 0.0001

THR 289 MET 290 0.0001

MET 290 SER 291 0.0004

SER 291 HIS 292 -0.0003

HIS 292 TYR 293 0.0002

TYR 293 TYR 294 0.0000

TYR 294 ASP 295 -0.0000

ASP 295 TYR 296 -0.0001

TYR 296 PRO 297 0.0004

PRO 297 SER 298 -0.0034

SER 298 ILE 299 -0.0002

ILE 299 ALA 300 -0.0001

ALA 300 HIS 301 0.0004

HIS 301 LEU 302 -0.0000

LEU 302 VAL 303 0.0000

VAL 303 GLN 304 -0.0001

GLN 304 LYS 305 -0.0001

LYS 305 LEU 306 -0.0003

LEU 306 SER 307 0.0003

SER 307 GLU 308 0.0000

GLU 308 ASN 309 -0.0000

ASN 309 ASN 310 -0.0003

ASN 310 ILE 311 -0.0001

ILE 311 GLN 312 -0.0003

GLN 312 THR 313 0.0029

THR 313 ILE 314 0.0001

ILE 314 PHE 315 -0.0001

PHE 315 ALA 316 -0.0002

ALA 316 VAL 317 -0.0003

VAL 317 THR 318 -0.0001

THR 318 GLU 319 0.0003

GLU 319 GLU 320 -0.0001

GLU 320 PHE 321 -0.0005

PHE 321 GLN 322 -0.0002

GLN 322 PRO 323 -0.0003

PRO 323 VAL 324 0.0002

VAL 324 TYR 325 0.0000

TYR 325 LYS 326 0.0002

LYS 326 GLU 327 -0.0001

GLU 327 LEU 328 0.0014

LEU 328 LYS 329 -0.0003

LYS 329 ASN 330 0.0002

ASN 330 LEU 331 0.0005

LEU 331 ILE 332 -0.0001

ILE 332 PRO 333 -0.0001

PRO 333 LYS 334 0.0001

LYS 334 SER 335 -0.0000

SER 335 ALA 336 0.0002

ALA 336 VAL 337 -0.0002

VAL 337 GLY 338 -0.0001

GLY 338 THR 339 0.0000

THR 339 LEU 340 -0.0002

LEU 340 SER 341 0.0002

SER 341 ALA 342 0.0002

ALA 342 ASN 343 0.0053

ASN 343 SER 344 -0.0002

SER 344 SER 345 0.0001

SER 345 ASN 346 -0.0003

ASN 346 VAL 347 0.0001

VAL 347 ILE 348 0.0001

ILE 348 GLN 349 -0.0002

GLN 349 LEU 350 0.0001

LEU 350 ILE 351 -0.0004

ILE 351 ILE 352 0.0001

ILE 352 ASP 353 -0.0002

ASP 353 ALA 354 0.0002

ALA 354 TYR 355 -0.0002

TYR 355 ASN 356 -0.0002

ASN 356 SER 357 -0.0000

SER 357 LEU 358 0.0046

LEU 358 SER 359 -0.0002

SER 359 SER 360 0.0002

SER 360 GLU 361 -0.0002

GLU 361 VAL 362 0.0001

VAL 362 ILE 363 0.0000

ILE 363 LEU 364 -0.0000

LEU 364 GLU 365 0.0000

GLU 365 ASN 366 0.0002

ASN 366 GLY 367 -0.0000

GLY 367 LYS 368 0.0000

LYS 368 LEU 369 -0.0003

LEU 369 SER 370 0.0002

SER 370 GLU 371 0.0004

GLU 371 GLY 372 -0.0001

GLY 372 VAL 373 0.0032

VAL 373 THR 374 -0.0002

THR 374 ILE 375 0.0002

ILE 375 SER 376 0.0001

SER 376 TYR 377 0.0000

TYR 377 LYS 378 -0.0002

LYS 378 SER 379 -0.0002

SER 379 TYR 380 0.0001

TYR 380 CYS 381 -0.0005

CYS 381 LYS 382 -0.0002

LYS 382 ASN 383 0.0003

ASN 383 GLY 384 0.0005

GLY 384 VAL 385 0.0002

VAL 385 ASN 386 -0.0002

ASN 386 GLY 387 0.0000

GLY 387 THR 388 -0.0018

THR 388 GLY 389 0.0001

GLY 389 GLU 390 -0.0003

GLU 390 ASN 391 -0.0001

ASN 391 GLY 392 0.0000

GLY 392 ARG 393 -0.0001

ARG 393 LYS 394 -0.0001

LYS 394 CYS 395 -0.0004

CYS 395 SER 396 0.0001

SER 396 ASN 397 0.0003

ASN 397 ILE 398 -0.0002

ILE 398 SER 399 0.0005

SER 399 ILE 400 -0.0003

ILE 400 GLY 401 -0.0002

GLY 401 ASP 402 0.0000

ASP 402 GLU 403 -0.0001

GLU 403 VAL 404 0.0001

VAL 404 GLN 405 0.0002

GLN 405 PHE 406 0.0000

PHE 406 GLU 407 -0.0001

GLU 407 ILE 408 -0.0003

ILE 408 SER 409 -0.0002

SER 409 ILE 410 0.0002

ILE 410 THR 411 0.0000

THR 411 SER 412 -0.0001

SER 412 ASN 413 0.0001

ASN 413 LYS 414 -0.0002

LYS 414 CYS 415 -0.0001

CYS 415 PRO 416 0.0003

PRO 416 LYS 417 0.0002

LYS 417 LYS 418 0.0015

LYS 418 ASP 419 -0.0003

ASP 419 SER 420 -0.0001

SER 420 ASP 421 -0.0001

ASP 421 SER 422 -0.0001

SER 422 PHE 423 -0.0000

PHE 423 LYS 424 0.0001

LYS 424 ILE 425 -0.0004

ILE 425 ARG 426 -0.0001

ARG 426 PRO 427 0.0000

PRO 427 LEU 428 -0.0002

LEU 428 GLY 429 -0.0001

GLY 429 PHE 430 -0.0000

PHE 430 THR 431 -0.0002

THR 431 GLU 432 -0.0002

GLU 432 GLU 433 -0.0007

GLU 433 VAL 434 0.0004

VAL 434 GLU 435 0.0000

GLU 435 VAL 436 0.0004

VAL 436 ILE 437 -0.0001

ILE 437 LEU 438 -0.0001

LEU 438 GLN 439 0.0000

GLN 439 TYR 440 0.0000

TYR 440 ILE 441 0.0004

ILE 441 CYS 442 -0.0003

CYS 442 GLU 443 0.0002

GLU 443 CYS 444 -0.0002

CYS 444 GLU 445 0.0000

GLU 445 PHE 1 -0.0020

PHE 1 ASN 2 0.0001

ASN 2 LEU 3 -0.0003

LEU 3 ASP 4 0.0000

ASP 4 ALA 5 -0.0002

ALA 5 GLU 6 -0.0002

GLU 6 ALA 7 0.0001

ALA 7 PRO 8 -0.0001

PRO 8 ALA 9 0.0002

ALA 9 VAL 10 -0.0001

VAL 10 LEU 11 0.0005

LEU 11 SER 12 0.0001

SER 12 GLY 13 -0.0002

GLY 13 PRO 14 -0.0001

PRO 14 PRO 15 0.0004

PRO 15 GLY 16 0.0007

GLY 16 SER 17 -0.0003

SER 17 PHE 18 0.0004

PHE 18 PHE 19 0.0003

PHE 19 GLY 20 -0.0001

GLY 20 PHE 21 -0.0002

PHE 21 SER 22 0.0004

SER 22 VAL 23 0.0001

VAL 23 GLU 24 0.0001

GLU 24 PHE 25 0.0000

PHE 25 TYR 26 0.0002

TYR 26 ARG 27 0.0003

ARG 27 PRO 28 -0.0003

PRO 28 GLY 29 0.0003

GLY 29 THR 30 0.0002

THR 30 ASP 31 -0.0007

ASP 31 GLY 32 0.0003

GLY 32 VAL 33 -0.0001

VAL 33 SER 34 -0.0002

SER 34 VAL 35 -0.0004

VAL 35 LEU 36 0.0003

LEU 36 VAL 37 -0.0002

VAL 37 GLY 38 0.0001

GLY 38 ALA 39 -0.0002

ALA 39 PRO 40 0.0000

PRO 40 LYS 41 0.0001

LYS 41 ALA 42 -0.0002

ALA 42 ASN 43 0.0003

ASN 43 THR 44 -0.0001

THR 44 SER 45 -0.0003

SER 45 GLN 46 0.0012

GLN 46 PRO 47 0.0001

PRO 47 GLY 48 0.0004

GLY 48 VAL 49 -0.0004

VAL 49 LEU 50 -0.0003

LEU 50 GLN 51 0.0000

GLN 51 GLY 52 -0.0003

GLY 52 GLY 53 0.0001

GLY 53 ALA 54 0.0001

ALA 54 VAL 55 -0.0002

VAL 55 TYR 56 0.0002

TYR 56 LEU 57 -0.0002

LEU 57 CYS 58 0.0003

CYS 58 PRO 59 0.0001

PRO 59 TRP 60 -0.0002

TRP 60 GLY 61 -0.0013

GLY 61 ALA 62 0.0003

ALA 62 SER 63 0.0002

SER 63 PRO 64 -0.0001

PRO 64 THR 65 -0.0000

THR 65 GLN 66 0.0000

GLN 66 CYS 67 0.0004

CYS 67 THR 68 -0.0003

THR 68 PRO 69 0.0003

PRO 69 ILE 70 -0.0000

ILE 70 GLU 71 -0.0002

GLU 71 PHE 72 -0.0001

PHE 72 ASP 73 0.0002

ASP 73 SER 74 0.0001

SER 74 LYS 75 -0.0002

LYS 75 GLY 76 0.0010

GLY 76 SER 77 0.0002

SER 77 ARG 78 0.0005

ARG 78 LEU 79 -0.0001

LEU 79 LEU 80 -0.0000

LEU 80 GLU 81 0.0004

GLU 81 SER 82 0.0002

SER 82 SER 83 0.0000

SER 83 LEU 84 0.0003

LEU 84 SER 85 0.0001

SER 85 SER 86 -0.0003

SER 86 SER 87 0.0001

SER 87 GLU 88 0.0002

GLU 88 GLY 89 0.0002

GLY 89 GLU 90 -0.0005

GLU 90 GLU 91 0.0000

GLU 91 PRO 92 -0.0002

PRO 92 VAL 93 0.0005

VAL 93 GLU 94 0.0001

GLU 94 TYR 95 -0.0001

TYR 95 LYS 96 0.0006

LYS 96 SER 97 -0.0003

SER 97 LEU 98 -0.0002

LEU 98 GLN 99 0.0003

GLN 99 TRP 100 0.0001

TRP 100 PHE 101 -0.0002

PHE 101 GLY 102 -0.0002

GLY 102 ALA 103 0.0001

ALA 103 THR 104 -0.0004

THR 104 VAL 105 0.0001

VAL 105 ARG 106 -0.0026

ARG 106 ALA 107 -0.0001

ALA 107 HIS 108 -0.0001

HIS 108 GLY 109 -0.0002

GLY 109 SER 110 -0.0000

SER 110 SER 111 -0.0002

SER 111 ILE 112 -0.0001

ILE 112 LEU 113 0.0004

LEU 113 ALA 114 -0.0001

ALA 114 CYS 115 0.0000

CYS 115 ALA 116 0.0000

ALA 116 PRO 117 0.0002

PRO 117 LEU 118 0.0002

LEU 118 TYR 119 0.0002

TYR 119 SER 120 0.0002

SER 120 TRP 121 0.0001

TRP 121 ARG 122 0.0004

ARG 122 THR 123 0.0002

THR 123 GLU 124 -0.0002

GLU 124 LYS 125 0.0001

LYS 125 GLU 126 -0.0000

GLU 126 PRO 127 0.0002

PRO 127 LEU 128 0.0002

LEU 128 SER 129 -0.0001

SER 129 ASP 130 0.0000

ASP 130 PRO 131 -0.0002

PRO 131 VAL 132 0.0001

VAL 132 GLY 133 0.0001

GLY 133 THR 134 -0.0002

THR 134 CYS 135 0.0001

CYS 135 TYR 136 0.0004

TYR 136 LEU 137 0.0003

LEU 137 SER 138 0.0000

SER 138 THR 139 0.0001

THR 139 ASP 140 -0.0002

ASP 140 ASN 141 -0.0000

ASN 141 PHE 142 0.0006

PHE 142 THR 143 -0.0003

THR 143 ARG 144 -0.0001

ARG 144 ILE 145 0.0002

ILE 145 LEU 146 -0.0001

LEU 146 GLU 147 0.0004

GLU 147 TYR 148 -0.0004

TYR 148 ALA 149 0.0002

ALA 149 PRO 150 0.0000

PRO 150 CYS 151 0.0022

CYS 151 ARG 152 0.0001

ARG 152 SER 153 -0.0002

SER 153 ASP 154 0.0001

ASP 154 PHE 155 -0.0001

PHE 155 SER 156 0.0002

SER 156 TRP 157 -0.0001

TRP 157 ALA 158 0.0000

ALA 158 ALA 159 -0.0001

ALA 159 GLY 160 -0.0001

GLY 160 GLN 161 0.0002

GLN 161 GLY 162 -0.0001

GLY 162 TYR 163 0.0002

TYR 163 CYS 164 -0.0002

CYS 164 GLN 165 -0.0000

GLN 165 GLY 166 -0.0023

GLY 166 GLY 167 -0.0001

GLY 167 PHE 168 0.0002

PHE 168 SER 169 0.0000

SER 169 ALA 170 0.0001

ALA 170 GLU 171 0.0001

GLU 171 PHE 172 -0.0003

PHE 172 THR 173 0.0002

THR 173 LYS 174 -0.0002

LYS 174 THR 175 0.0000

THR 175 GLY 176 0.0000

GLY 176 ARG 177 -0.0001

ARG 177 VAL 178 0.0001

VAL 178 VAL 179 0.0000

VAL 179 LEU 180 -0.0004

LEU 180 GLY 181 0.0043

GLY 181 GLY 182 0.0000

GLY 182 PRO 183 -0.0001

PRO 183 GLY 184 0.0001

GLY 184 SER 185 0.0001

SER 185 TYR 186 -0.0000

TYR 186 PHE 187 -0.0000

PHE 187 TRP 188 0.0000

TRP 188 GLN 189 0.0002

GLN 189 GLY 190 0.0001

GLY 190 GLN 191 0.0005

GLN 191 ILE 192 -0.0002

ILE 192 LEU 193 -0.0000

LEU 193 SER 194 0.0002

SER 194 ALA 195 -0.0000

ALA 195 THR 196 0.0042

THR 196 GLN 197 -0.0002

GLN 197 GLU 198 0.0002

GLU 198 GLN 199 -0.0001

GLN 199 ILE 200 0.0002

ILE 200 ALA 201 0.0005

ALA 201 GLU 202 0.0000

GLU 202 SER 203 -0.0002

SER 203 TYR 204 -0.0003

TYR 204 TYR 205 0.0004

TYR 205 PRO 206 -0.0003

PRO 206 GLU 207 -0.0003

GLU 207 TYR 208 -0.0002

TYR 208 LEU 209 -0.0000

LEU 209 ILE 210 -0.0002

ILE 210 ASN 211 -0.0021

ASN 211 LEU 212 -0.0003

LEU 212 VAL 213 -0.0001

VAL 213 GLN 214 -0.0003

GLN 214 GLY 215 0.0002

GLY 215 GLN 216 -0.0001

GLN 216 LEU 217 -0.0000

LEU 217 GLN 218 0.0001

GLN 218 THR 219 -0.0002

THR 219 ARG 220 0.0000

ARG 220 GLN 221 -0.0001

GLN 221 ALA 222 0.0002

ALA 222 SER 223 -0.0001

SER 223 SER 224 0.0000

SER 224 ILE 225 0.0000

ILE 225 TYR 226 0.0000

TYR 226 ASP 227 0.0003

ASP 227 ASP 228 -0.0000

ASP 228 SER 229 0.0002

SER 229 TYR 230 -0.0001

TYR 230 LEU 231 -0.0001

LEU 231 GLY 232 -0.0002

GLY 232 TYR 233 -0.0002

TYR 233 SER 234 -0.0002

SER 234 VAL 235 -0.0001

VAL 235 ALA 236 0.0000

ALA 236 VAL 237 0.0004

VAL 237 GLY 238 -0.0001

GLY 238 GLU 239 -0.0001

GLU 239 PHE 240 0.0001

PHE 240 SER 241 -0.0052

SER 241 GLY 242 0.0003

GLY 242 ASP 243 -0.0001

ASP 243 ASP 244 -0.0003

ASP 244 THR 245 0.0004

THR 245 GLU 246 0.0000

GLU 246 ASP 247 0.0004

ASP 247 PHE 248 -0.0000

PHE 248 VAL 249 -0.0004

VAL 249 ALA 250 0.0006

ALA 250 GLY 251 -0.0001

GLY 251 VAL 252 0.0001

VAL 252 PRO 253 0.0001

PRO 253 LYS 254 0.0002

LYS 254 GLY 255 -0.0001

GLY 255 ASN 256 -0.0030

ASN 256 LEU 257 0.0001

LEU 257 THR 258 -0.0003

THR 258 TYR 259 -0.0002

TYR 259 GLY 260 0.0002

GLY 260 TYR 261 -0.0003

TYR 261 VAL 262 0.0000

VAL 262 THR 263 -0.0001

THR 263 ILE 264 -0.0003

ILE 264 LEU 265 0.0003

LEU 265 ASN 266 -0.0003

ASN 266 GLY 267 0.0004

GLY 267 SER 268 -0.0000

SER 268 ASP 269 0.0003

ASP 269 ILE 270 -0.0001

ILE 270 ARG 271 -0.0023

ARG 271 SER 272 0.0000

SER 272 LEU 273 -0.0002

LEU 273 TYR 274 0.0001

TYR 274 ASN 275 0.0001

ASN 275 PHE 276 0.0001

PHE 276 SER 277 -0.0001

SER 277 GLY 278 0.0006

GLY 278 GLU 279 -0.0003

GLU 279 GLN 280 -0.0002

GLN 280 MET 281 0.0002

MET 281 ALA 282 0.0002

ALA 282 SER 283 0.0001

SER 283 TYR 284 0.0002

TYR 284 PHE 285 -0.0004

PHE 285 GLY 286 0.0058

GLY 286 TYR 287 0.0002

TYR 287 ALA 288 -0.0000

ALA 288 VAL 289 -0.0003

VAL 289 ALA 290 -0.0001

ALA 290 ALA 291 0.0001

ALA 291 THR 292 -0.0002

THR 292 ASP 293 0.0001

ASP 293 VAL 294 -0.0001

VAL 294 ASN 295 0.0002

ASN 295 GLY 296 0.0002

GLY 296 ASP 297 0.0001

ASP 297 GLY 298 -0.0001

GLY 298 LEU 299 0.0003

LEU 299 ASP 300 0.0001

ASP 300 ASP 301 0.0014

ASP 301 LEU 302 -0.0002

LEU 302 LEU 303 0.0001

LEU 303 VAL 304 0.0001

VAL 304 GLY 305 -0.0000

GLY 305 ALA 306 -0.0004

ALA 306 PRO 307 0.0001

PRO 307 LEU 308 -0.0003

LEU 308 LEU 309 -0.0001

LEU 309 MET 310 -0.0001

MET 310 ASP 311 -0.0002

ASP 311 ARG 312 0.0003

ARG 312 THR 313 0.0000

THR 313 PRO 314 0.0005

PRO 314 ASP 315 0.0003

ASP 315 GLY 316 -0.0046

GLY 316 ARG 317 -0.0002

ARG 317 PRO 318 0.0004

PRO 318 GLN 319 -0.0002

GLN 319 GLU 320 -0.0002

GLU 320 VAL 321 -0.0001

VAL 321 GLY 322 -0.0001

GLY 322 ARG 323 0.0001

ARG 323 VAL 324 0.0001

VAL 324 TYR 325 -0.0003

TYR 325 VAL 326 0.0001

VAL 326 TYR 327 0.0006

TYR 327 LEU 328 -0.0001

LEU 328 GLN 329 0.0002

GLN 329 HIS 330 0.0003

HIS 330 PRO 331 0.0017

PRO 331 ALA 332 0.0001

ALA 332 GLY 333 0.0002

GLY 333 ILE 334 -0.0001

ILE 334 GLU 335 -0.0000

GLU 335 PRO 336 0.0002

PRO 336 THR 337 -0.0001

THR 337 PRO 338 -0.0002

PRO 338 THR 339 0.0002

THR 339 LEU 340 0.0000

LEU 340 THR 341 0.0001

THR 341 LEU 342 -0.0001

LEU 342 THR 343 0.0004

THR 343 GLY 344 -0.0004

GLY 344 HIS 345 -0.0000

HIS 345 ASP 346 0.0003

ASP 346 GLU 347 0.0001

GLU 347 PHE 348 0.0005

PHE 348 GLY 349 -0.0000

GLY 349 ARG 350 -0.0002

ARG 350 PHE 351 0.0002

PHE 351 GLY 352 -0.0000

GLY 352 SER 353 -0.0000

SER 353 SER 354 -0.0002

SER 354 LEU 355 0.0004

LEU 355 THR 356 0.0000

THR 356 PRO 357 0.0000

PRO 357 LEU 358 0.0002

LEU 358 GLY 359 0.0003

GLY 359 ASP 360 -0.0003

ASP 360 LEU 361 0.0021

LEU 361 ASP 362 0.0004

ASP 362 GLN 363 0.0002

GLN 363 ASP 364 0.0003

ASP 364 GLY 365 -0.0001

GLY 365 TYR 366 0.0005

TYR 366 ASN 367 -0.0002

ASN 367 ASP 368 -0.0003

ASP 368 VAL 369 0.0002

VAL 369 ALA 370 -0.0000

ALA 370 ILE 371 0.0005

ILE 371 GLY 372 -0.0002

GLY 372 ALA 373 -0.0003

ALA 373 PRO 374 0.0002

PRO 374 PHE 375 0.0001

PHE 375 GLY 376 -0.0015

GLY 376 GLY 377 0.0003

GLY 377 GLU 378 0.0001

GLU 378 THR 379 -0.0005

THR 379 GLN 380 -0.0004

GLN 380 GLN 381 0.0000

GLN 381 GLY 382 -0.0004

GLY 382 VAL 383 0.0001

VAL 383 VAL 384 -0.0001

VAL 384 PHE 385 0.0001

PHE 385 VAL 386 -0.0000

VAL 386 PHE 387 0.0004

PHE 387 PRO 388 0.0001

PRO 388 GLY 389 0.0002

GLY 389 GLY 390 -0.0003

GLY 390 PRO 391 -0.0003

PRO 391 GLY 392 0.0004

GLY 392 GLY 393 0.0000

GLY 393 LEU 394 -0.0001

LEU 394 GLY 395 0.0004

GLY 395 SER 396 0.0001

SER 396 LYS 397 0.0001

LYS 397 PRO 398 0.0001

PRO 398 SER 399 0.0004

SER 399 GLN 400 -0.0001

GLN 400 VAL 401 -0.0002

VAL 401 LEU 402 0.0000

LEU 402 GLN 403 0.0000

GLN 403 PRO 404 0.0002

PRO 404 LEU 405 -0.0004

LEU 405 TRP 406 -0.0016

TRP 406 ALA 407 0.0000

ALA 407 ALA 408 -0.0002

ALA 408 SER 409 0.0000

SER 409 HIS 410 -0.0001

HIS 410 THR 411 -0.0004

THR 411 PRO 412 -0.0001

PRO 412 ASP 413 -0.0001

ASP 413 PHE 414 -0.0003

PHE 414 PHE 415 -0.0002

PHE 415 GLY 416 0.0001

GLY 416 SER 417 -0.0002

SER 417 ALA 418 -0.0000

ALA 418 LEU 419 0.0001

LEU 419 ARG 420 0.0000

ARG 420 GLY 421 0.0008

GLY 421 GLY 422 0.0001

GLY 422 ARG 423 0.0002

ARG 423 ASP 424 0.0001

ASP 424 LEU 425 0.0000

LEU 425 ASP 426 0.0001

ASP 426 GLY 427 -0.0002

GLY 427 ASN 428 0.0003

ASN 428 GLY 429 0.0001

GLY 429 TYR 430 0.0001

TYR 430 PRO 431 -0.0002

PRO 431 ASP 432 -0.0004

ASP 432 LEU 433 0.0000

LEU 433 ILE 434 -0.0001

ILE 434 VAL 435 -0.0003

VAL 435 GLY 436 0.0003

GLY 436 SER 437 0.0000

SER 437 PHE 438 0.0003

PHE 438 GLY 439 -0.0002

GLY 439 VAL 440 0.0001

VAL 440 ASP 441 -0.0001

ASP 441 LYS 442 0.0002

LYS 442 ALA 443 0.0001

ALA 443 VAL 444 -0.0001

VAL 444 VAL 445 0.0000

VAL 445 TYR 446 -0.0004

TYR 446 ARG 447 0.0000

ARG 447 GLY 448 0.0000

GLY 448 ARG 449 -0.0004

ARG 449 PRO 450 0.0001

PRO 450 ILE 451 0.0001

ILE 451 VAL 452 0.0001

VAL 452 SER 453 0.0001

SER 453 ALA 454 0.0002

ALA 454 SER 455 0.0001

SER 455 ALA 456 -0.0002

ALA 456 SER 457 -0.0001

SER 457 LEU 458 -0.0000

LEU 458 THR 459 0.0004

THR 459 ILE 460 -0.0001

ILE 460 PHE 461 -0.0003

PHE 461 PRO 462 -0.0003

PRO 462 ALA 463 -0.0000

ALA 463 MET 464 0.0000

MET 464 PHE 465 -0.0003

PHE 465 ASN 466 0.0001

ASN 466 PRO 467 0.0001

PRO 467 GLU 468 -0.0001

GLU 468 GLU 469 0.0001

GLU 469 ARG 470 0.0000

ARG 470 SER 471 0.0000

SER 471 CYS 472 0.0000

CYS 472 SER 473 -0.0001

SER 473 LEU 474 0.0003

LEU 474 GLU 475 0.0002

GLU 475 GLY 476 -0.0002

GLY 476 ASN 477 -0.0000

ASN 477 PRO 478 0.0000

PRO 478 VAL 479 -0.0004

VAL 479 ALA 480 -0.0000

ALA 480 CYS 481 0.0008

CYS 481 ILE 482 -0.0000

ILE 482 ASN 483 -0.0001

ASN 483 LEU 484 -0.0001

LEU 484 SER 485 0.0002

SER 485 PHE 486 0.0000

PHE 486 CYS 487 -0.0005

CYS 487 LEU 488 0.0001

LEU 488 ASN 489 0.0001

ASN 489 ALA 490 -0.0002

ALA 490 SER 491 0.0000

SER 491 GLY 492 0.0001

GLY 492 LYS 493 0.0004

LYS 493 HIS 494 0.0002

HIS 494 VAL 495 -0.0002

VAL 495 ALA 496 0.0014

ALA 496 ASP 497 -0.0001

ASP 497 SER 498 -0.0003

SER 498 ILE 499 0.0003

ILE 499 GLY 500 -0.0002

GLY 500 PHE 501 -0.0001

PHE 501 THR 502 0.0003

THR 502 VAL 503 -0.0000

VAL 503 GLU 504 -0.0002

GLU 504 LEU 505 0.0003

LEU 505 GLN 506 -0.0005

GLN 506 LEU 507 -0.0001

LEU 507 ASP 508 0.0003

ASP 508 TRP 509 0.0002

TRP 509 GLN 510 -0.0002

GLN 510 LYS 511 -0.0010

LYS 511 GLN 512 -0.0002

GLN 512 ARG 518 -0.0001

ARG 518 ALA 519 -0.0000

ALA 519 LEU 520 -0.0002

LEU 520 PHE 521 0.0002

PHE 521 LEU 522 -0.0002

LEU 522 ALA 523 0.0001

ALA 523 SER 524 0.0002

SER 524 ARG 525 -0.0000

ARG 525 GLN 526 0.0002

GLN 526 ALA 527 0.0000

ALA 527 THR 528 0.0002

THR 528 LEU 529 -0.0004

LEU 529 THR 530 0.0003

THR 530 GLN 531 0.0001

GLN 531 THR 532 0.0000

THR 532 LEU 533 0.0003

LEU 533 LEU 534 0.0000

LEU 534 ILE 535 -0.0000

ILE 535 GLN 536 -0.0001

GLN 536 ASN 537 -0.0002

ASN 537 GLY 538 -0.0002

GLY 538 ALA 539 0.0001

ALA 539 ARG 540 0.0001

ARG 540 GLU 541 0.0002

GLU 541 ASP 542 -0.0000

ASP 542 CYS 543 -0.0000

CYS 543 ARG 544 0.0000

ARG 544 GLU 545 -0.0001

GLU 545 MET 546 0.0001

MET 546 LYS 547 0.0001

LYS 547 ILE 548 -0.0001

ILE 548 TYR 549 0.0001

TYR 549 LEU 550 0.0000

LEU 550 ARG 551 0.0004

ARG 551 ASN 552 0.0000

ASN 552 GLU 553 0.0001

GLU 553 LEU 560 -0.0014

LEU 560 SER 561 0.0000

SER 561 PRO 562 0.0001

PRO 562 ILE 563 0.0001

ILE 563 HIS 564 -0.0003

HIS 564 ILE 565 0.0001

ILE 565 ALA 566 0.0002

ALA 566 LEU 567 -0.0003

LEU 567 ASN 568 0.0001

ASN 568 PHE 569 0.0001

PHE 569 SER 570 0.0000

SER 570 LEU 571 0.0001

LEU 571 ASP 572 0.0001

ASP 572 PRO 573 -0.0001

PRO 573 GLN 574 -0.0004

GLN 574 ALA 575 0.0051

ALA 575 PRO 576 0.0002

PRO 576 VAL 577 0.0002

VAL 577 ASP 578 -0.0004

ASP 578 SER 579 0.0000

SER 579 HIS 580 0.0003

HIS 580 GLY 581 -0.0003

GLY 581 LEU 582 -0.0002

LEU 582 ARG 583 0.0002

ARG 583 PRO 584 -0.0001

PRO 584 ALA 585 0.0002

ALA 585 LEU 586 0.0001

LEU 586 HIS 587 -0.0001

HIS 587 TYR 588 -0.0003

TYR 588 GLN 589 0.0001

GLN 589 SER 590 0.0007

SER 590 LYS 591 -0.0003

LYS 591 SER 592 -0.0001

SER 592 ARG 593 0.0002

ARG 593 ILE 594 0.0000

ILE 594 GLU 595 0.0002

GLU 595 ASP 596 0.0000

ASP 596 LYS 597 -0.0001

LYS 597 ALA 598 0.0004

ALA 598 GLN 599 -0.0003

GLN 599 ILE 600 0.0000

ILE 600 ASN 5 0.0145

ASN 5 ARG 6 -0.0003

ARG 6 CYS 7 0.0002

CYS 7 LEU 8 0.0001

LEU 8 LYS 9 -0.0002

LYS 9 ALA 10 -0.0000

ALA 10 ASN 11 -0.0001

ASN 11 ALA 12 -0.0002

ALA 12 LYS 13 0.0003

LYS 13 SER 14 -0.0002

SER 14 CYS 15 0.0002

CYS 15 GLY 16 -0.0001

GLY 16 GLU 17 0.0004

GLU 17 CYS 18 0.0000

CYS 18 ILE 19 0.0000

ILE 19 GLN 20 -0.0002

GLN 20 ALA 21 -0.0000

ALA 21 GLY 22 0.0001

GLY 22 PRO 23 -0.0000

PRO 23 ASN 24 -0.0001

ASN 24 CYS 25 -0.0000

CYS 25 GLY 26 -0.0000

GLY 26 TRP 27 -0.0000

TRP 27 CYS 28 -0.0002

CYS 28 THR 29 -0.0001

THR 29 ASN 30 0.0001

ASN 30 SER 31 -0.0002

SER 31 THR 32 0.0001

THR 32 PHE 33 0.0001

PHE 33 ARG 43 0.0003

ARG 43 CYS 44 -0.0001

CYS 44 ASP 45 0.0001

ASP 45 ASP 46 0.0003

ASP 46 LEU 47 -0.0001

LEU 47 GLU 48 -0.0001

GLU 48 ALA 49 0.0005

ALA 49 LEU 50 0.0001

LEU 50 LYS 51 -0.0001

LYS 51 LYS 52 -0.0001

LYS 52 LYS 53 -0.0003

LYS 53 GLY 54 0.0003

GLY 54 CYS 55 0.0001

CYS 55 PRO 56 0.0002

PRO 56 PRO 57 0.0003

PRO 57 ASP 58 0.0031

ASP 58 ASP 59 0.0000

ASP 59 ILE 60 -0.0002

ILE 60 GLU 61 0.0001

GLU 61 ASN 62 -0.0002

ASN 62 PRO 63 0.0002

PRO 63 ARG 64 -0.0000

ARG 64 GLY 65 -0.0002

GLY 65 SER 66 -0.0001

SER 66 LYS 67 0.0001

LYS 67 ASP 68 -0.0002

ASP 68 ILE 69 0.0000

ILE 69 LYS 70 -0.0002

LYS 70 LYS 71 0.0000

LYS 71 ASN 72 -0.0001

ASN 72 LYS 73 -0.0191

LYS 73 ASN 74 -0.0002

ASN 74 VAL 75 0.0001

VAL 75 THR 76 0.0003

THR 76 ASN 77 0.0005

ASN 77 ARG 78 -0.0002

ARG 78 SER 79 0.0000

SER 79 LYS 80 0.0001

LYS 80 GLY 81 0.0000

GLY 81 THR 82 0.0000

THR 82 ALA 83 0.0002

ALA 83 GLU 84 0.0005

GLU 84 LYS 85 -0.0002

LYS 85 LEU 86 -0.0001

LEU 86 LYS 87 0.0000

LYS 87 PRO 88 -0.0271

PRO 88 GLU 89 -0.0001

GLU 89 ASP 90 -0.0000

ASP 90 ILE 91 -0.0001

ILE 91 HIS 92 0.0001

HIS 92 GLN 93 -0.0003

GLN 93 ILE 94 0.0002

ILE 94 GLN 95 -0.0003

GLN 95 PRO 96 -0.0000

PRO 96 GLN 97 0.0000

GLN 97 GLN 98 -0.0002

GLN 98 LEU 99 0.0000

LEU 99 VAL 100 -0.0001

VAL 100 LEU 101 0.0001

LEU 101 ARG 102 0.0002

ARG 102 LEU 103 -0.0017

LEU 103 ARG 104 0.0001

ARG 104 SER 105 -0.0002

SER 105 GLY 106 0.0001

GLY 106 GLU 107 0.0001

GLU 107 PRO 108 -0.0001

PRO 108 GLN 109 -0.0002

GLN 109 THR 110 0.0002

THR 110 PHE 111 0.0000

PHE 111 THR 112 -0.0000

THR 112 LEU 113 -0.0002

LEU 113 LYS 114 0.0002

LYS 114 PHE 115 -0.0002

PHE 115 LYS 116 0.0004

LYS 116 ARG 117 -0.0004

ARG 117 ALA 118 -0.0087

ALA 118 GLU 119 0.0000

GLU 119 ASP 120 -0.0002

ASP 120 TYR 121 0.0001

TYR 121 PRO 122 0.0001

PRO 122 ILE 123 -0.0005

ILE 123 ASP 124 0.0002

ASP 124 LEU 125 0.0001

LEU 125 TYR 126 0.0002

TYR 126 TYR 127 -0.0003

TYR 127 LEU 128 0.0004

LEU 128 MET 129 -0.0001

MET 129 ASP 130 -0.0003

ASP 130 LEU 131 -0.0002

LEU 131 SER 132 -0.0001

SER 132 TYR 133 -0.0041

TYR 133 SER 134 0.0001

SER 134 MET 135 0.0001

MET 135 LYS 136 0.0000

LYS 136 ASP 137 0.0001

ASP 137 ASP 138 0.0003

ASP 138 LEU 139 -0.0000

LEU 139 GLU 140 0.0002

GLU 140 ASN 141 0.0003

ASN 141 VAL 142 -0.0002

VAL 142 LYS 143 -0.0002

LYS 143 SER 144 0.0000

SER 144 LEU 145 0.0001

LEU 145 GLY 146 -0.0001

GLY 146 THR 147 0.0000

THR 147 ASP 148 -0.0141

ASP 148 LEU 149 0.0000

LEU 149 MET 150 -0.0003

MET 150 ASN 151 -0.0002

ASN 151 GLU 152 -0.0002

GLU 152 MET 153 0.0000

MET 153 ARG 154 -0.0001

ARG 154 ARG 155 0.0002

ARG 155 ILE 156 0.0002

ILE 156 THR 157 0.0001

THR 157 SER 158 0.0003

SER 158 ASP 159 -0.0001

ASP 159 PHE 160 -0.0001

PHE 160 ARG 161 0.0001

ARG 161 ILE 162 -0.0001

ILE 162 GLY 163 -0.0085

GLY 163 PHE 164 -0.0000

PHE 164 GLY 165 -0.0002

GLY 165 SER 166 0.0001

SER 166 PHE 167 -0.0002

PHE 167 VAL 168 0.0000

VAL 168 GLU 169 -0.0001

GLU 169 LYS 170 -0.0002

LYS 170 THR 171 -0.0000

THR 171 VAL 172 0.0000

VAL 172 MET 173 0.0001

MET 173 PRO 174 -0.0001

PRO 174 TYR 175 -0.0000

TYR 175 ILE 176 0.0000

ILE 176 SER 177 0.0000

SER 177 THR 178 -0.0003

THR 178 THR 179 0.0000

THR 179 PRO 180 -0.0001

PRO 180 ALA 181 -0.0001

ALA 181 LYS 182 -0.0000

LYS 182 LEU 183 -0.0002

LEU 183 ARG 184 -0.0004

ARG 184 ASN 185 -0.0002

ASN 185 PRO 186 0.0001

PRO 186 CYS 187 0.0001

CYS 187 THR 188 0.0001

THR 188 SER 189 -0.0003

SER 189 GLU 190 0.0002

GLU 190 GLN 191 -0.0002

GLN 191 ASN 192 0.0002

ASN 192 CYS 193 -0.0006

CYS 193 THR 194 0.0001

THR 194 THR 195 0.0003

THR 195 PRO 196 0.0001

PRO 196 PHE 197 -0.0003

PHE 197 SER 198 -0.0001

SER 198 TYR 199 -0.0002

TYR 199 LYS 200 0.0002

LYS 200 ASN 201 0.0002

ASN 201 VAL 202 0.0000

VAL 202 LEU 203 0.0001

LEU 203 SER 204 -0.0001

SER 204 LEU 205 -0.0002

LEU 205 THR 206 0.0004

THR 206 ASN 207 -0.0002

ASN 207 LYS 208 0.0043

LYS 208 GLY 209 0.0001

GLY 209 GLU 210 -0.0001

GLU 210 VAL 211 0.0002

VAL 211 PHE 212 0.0004

PHE 212 ASN 213 0.0001

ASN 213 GLU 214 0.0002

GLU 214 LEU 215 -0.0001

LEU 215 VAL 216 0.0001

VAL 216 GLY 217 -0.0004

GLY 217 LYS 218 -0.0003

LYS 218 GLN 219 0.0001

GLN 219 ARG 220 -0.0003

ARG 220 ILE 221 0.0002

ILE 221 SER 222 -0.0002

SER 222 GLY 223 0.0030

GLY 223 ASN 224 -0.0001

ASN 224 LEU 225 0.0003

LEU 225 ASP 226 -0.0004

ASP 226 SER 227 0.0002

SER 227 PRO 228 -0.0002

PRO 228 GLU 229 -0.0001

GLU 229 GLY 230 0.0003

GLY 230 GLY 231 -0.0004

GLY 231 PHE 232 0.0002

PHE 232 ASP 233 -0.0002

ASP 233 ALA 234 -0.0001

ALA 234 ILE 235 -0.0001

ILE 235 MET 236 0.0002

MET 236 GLN 237 -0.0003

GLN 237 VAL 238 -0.0064

VAL 238 ALA 239 -0.0001

ALA 239 VAL 240 0.0000

VAL 240 CYS 241 -0.0003

CYS 241 GLY 242 0.0001

GLY 242 SER 243 -0.0001

SER 243 LEU 244 -0.0002

LEU 244 ILE 245 0.0000

ILE 245 GLY 246 0.0000

GLY 246 TRP 247 -0.0002

TRP 247 ARG 248 0.0002

ARG 248 ASN 249 -0.0002

ASN 249 VAL 250 -0.0001

VAL 250 THR 251 -0.0001

THR 251 ARG 252 0.0000

ARG 252 LEU 253 0.0066

LEU 253 LEU 254 -0.0001

LEU 254 VAL 255 -0.0001

VAL 255 PHE 256 0.0001

PHE 256 SER 257 0.0001

SER 257 THR 258 -0.0002

THR 258 ASP 259 0.0001

ASP 259 ALA 260 0.0001

ALA 260 GLY 261 -0.0000

GLY 261 PHE 262 -0.0002

PHE 262 HIS 263 -0.0000

HIS 263 PHE 264 -0.0003

PHE 264 ALA 265 0.0002

ALA 265 GLY 266 -0.0001

GLY 266 ASP 267 -0.0000

ASP 267 GLY 268 0.0084

GLY 268 LYS 269 0.0002

LYS 269 LEU 270 -0.0002

LEU 270 GLY 271 0.0004

GLY 271 GLY 272 -0.0003

GLY 272 ILE 273 0.0001

ILE 273 VAL 274 0.0002

VAL 274 LEU 275 -0.0002

LEU 275 PRO 276 -0.0000

PRO 276 ASN 277 0.0001

ASN 277 ASP 278 -0.0002

ASP 278 GLY 279 -0.0001

GLY 279 GLN 280 0.0003

GLN 280 CYS 281 0.0003

CYS 281 HIS 282 -0.0001

HIS 282 LEU 283 -0.0030

LEU 283 GLU 284 -0.0001

GLU 284 ASN 285 -0.0002

ASN 285 ASN 286 -0.0004

ASN 286 MET 287 0.0001

MET 287 TYR 288 -0.0002

TYR 288 THR 289 -0.0001

THR 289 MET 290 0.0002

MET 290 SER 291 0.0001

SER 291 HIS 292 -0.0002

HIS 292 TYR 293 0.0001

TYR 293 TYR 294 -0.0002

TYR 294 ASP 295 0.0004

ASP 295 TYR 296 -0.0004

TYR 296 PRO 297 -0.0000

PRO 297 SER 298 0.0096

SER 298 ILE 299 0.0000

ILE 299 ALA 300 -0.0002

ALA 300 HIS 301 0.0002

HIS 301 LEU 302 0.0000

LEU 302 VAL 303 0.0001

VAL 303 GLN 304 -0.0003

GLN 304 LYS 305 -0.0003

LYS 305 LEU 306 -0.0004

LEU 306 SER 307 0.0005

SER 307 GLU 308 -0.0002

GLU 308 ASN 309 -0.0003

ASN 309 ASN 310 -0.0000

ASN 310 ILE 311 0.0002

ILE 311 GLN 312 0.0002

GLN 312 THR 313 0.0004

THR 313 ILE 314 -0.0001

ILE 314 PHE 315 0.0000

PHE 315 ALA 316 -0.0002

ALA 316 VAL 317 0.0001

VAL 317 THR 318 0.0002

THR 318 GLU 319 -0.0000

GLU 319 GLU 320 0.0002

GLU 320 PHE 321 -0.0000

PHE 321 GLN 322 -0.0001

GLN 322 PRO 323 -0.0000

PRO 323 VAL 324 -0.0002

VAL 324 TYR 325 0.0005

TYR 325 LYS 326 -0.0000

LYS 326 GLU 327 -0.0001

GLU 327 LEU 328 -0.0051

LEU 328 LYS 329 -0.0003

LYS 329 ASN 330 -0.0002

ASN 330 LEU 331 0.0001

LEU 331 ILE 332 -0.0001

ILE 332 PRO 333 0.0003

PRO 333 LYS 334 -0.0002

LYS 334 SER 335 -0.0000

SER 335 ALA 336 0.0001

ALA 336 VAL 337 -0.0001

VAL 337 GLY 338 -0.0002

GLY 338 THR 339 0.0002

THR 339 LEU 340 -0.0001

LEU 340 SER 341 -0.0001

SER 341 ALA 342 0.0000

ALA 342 ASN 343 -0.0024

ASN 343 SER 344 0.0001

SER 344 SER 345 0.0001

SER 345 ASN 346 0.0001

ASN 346 VAL 347 -0.0002

VAL 347 ILE 348 0.0003

ILE 348 GLN 349 0.0004

GLN 349 LEU 350 0.0001

LEU 350 ILE 351 0.0003

ILE 351 ILE 352 -0.0001

ILE 352 ASP 353 -0.0000

ASP 353 ALA 354 -0.0001

ALA 354 TYR 355 -0.0001

TYR 355 ASN 356 0.0000

ASN 356 SER 357 -0.0001

SER 357 LEU 358 -0.0075

LEU 358 SER 359 -0.0001

SER 359 SER 360 -0.0002

SER 360 GLU 361 0.0001

GLU 361 VAL 362 -0.0002

VAL 362 ILE 363 -0.0001

ILE 363 LEU 364 0.0002

LEU 364 GLU 365 0.0000

GLU 365 ASN 366 -0.0002

ASN 366 GLY 367 0.0000

GLY 367 LYS 368 0.0003

LYS 368 LEU 369 -0.0002

LEU 369 SER 370 -0.0004

SER 370 GLU 371 0.0002

GLU 371 GLY 372 -0.0002

GLY 372 VAL 373 0.0004

VAL 373 THR 374 -0.0001

THR 374 ILE 375 0.0002

ILE 375 SER 376 0.0000

SER 376 TYR 377 0.0003

TYR 377 LYS 378 -0.0002

LYS 378 SER 379 0.0002

SER 379 TYR 380 -0.0002

TYR 380 CYS 381 0.0003

CYS 381 LYS 382 0.0002

LYS 382 ASN 383 -0.0001

ASN 383 GLY 384 -0.0001

GLY 384 VAL 385 0.0000

VAL 385 ASN 386 0.0002

ASN 386 GLY 387 -0.0001

GLY 387 THR 388 0.0000

THR 388 GLY 389 -0.0003

GLY 389 GLU 390 -0.0001

GLU 390 ASN 391 -0.0002

ASN 391 GLY 392 -0.0001

GLY 392 ARG 393 0.0001

ARG 393 LYS 394 -0.0001

LYS 394 CYS 395 0.0004

CYS 395 SER 396 -0.0003

SER 396 ASN 397 0.0004

ASN 397 ILE 398 -0.0000

ILE 398 SER 399 0.0000

SER 399 ILE 400 -0.0000

ILE 400 GLY 401 -0.0002

GLY 401 ASP 402 -0.0000

ASP 402 GLU 403 0.0057

GLU 403 VAL 404 0.0001

VAL 404 GLN 405 -0.0001

GLN 405 PHE 406 -0.0001

PHE 406 GLU 407 0.0001

GLU 407 ILE 408 -0.0002

ILE 408 SER 409 0.0000

SER 409 ILE 410 -0.0002

ILE 410 THR 411 0.0003

THR 411 SER 412 0.0001

SER 412 ASN 413 -0.0002

ASN 413 LYS 414 -0.0003

LYS 414 CYS 415 -0.0001

CYS 415 PRO 416 -0.0004

PRO 416 LYS 417 -0.0000

LYS 417 LYS 418 0.0005

LYS 418 ASP 419 0.0000

ASP 419 SER 420 0.0004

SER 420 ASP 421 -0.0001

ASP 421 SER 422 -0.0002

SER 422 PHE 423 0.0001

PHE 423 LYS 424 0.0002

LYS 424 ILE 425 0.0000

ILE 425 ARG 426 0.0001

ARG 426 PRO 427 -0.0002

PRO 427 LEU 428 -0.0001

LEU 428 GLY 429 -0.0000

GLY 429 PHE 430 -0.0002

PHE 430 THR 431 0.0002

THR 431 GLU 432 -0.0003

GLU 432 GLU 433 0.0039

GLU 433 VAL 434 -0.0001

VAL 434 GLU 435 0.0002

GLU 435 VAL 436 -0.0001

VAL 436 ILE 437 0.0002

ILE 437 LEU 438 0.0000

LEU 438 GLN 439 0.0001

GLN 439 TYR 440 0.0000

TYR 440 ILE 441 -0.0002

ILE 441 CYS 442 0.0003

CYS 442 GLU 443 -0.0001

GLU 443 CYS 444 -0.0001

CYS 444 GLU 445 -0.0002

GLU 445 ASP 1 -0.0058

ASP 1 ILE 2 -0.0001

ILE 2 VAL 3 -0.0004

VAL 3 MET 4 0.0000

MET 4 THR 5 0.0000

THR 5 GLN 6 -0.0004

GLN 6 ALA 7 -0.0002

ALA 7 THR 8 -0.0002

THR 8 PRO 9 -0.0001

PRO 9 SER 10 0.0002

SER 10 ILE 11 -0.0000

ILE 11 PRO 12 0.0003

PRO 12 VAL 13 -0.0000

VAL 13 THR 14 -0.0001

THR 14 PRO 15 0.0001

PRO 15 GLY 16 0.0071

GLY 16 GLU 17 -0.0004

GLU 17 SER 18 0.0001

SER 18 VAL 19 0.0003

VAL 19 SER 20 -0.0001

SER 20 ILE 21 -0.0000

ILE 21 SER 22 0.0001

SER 22 CYS 23 0.0001

CYS 23 ARG 24 0.0001

ARG 24 SER 25 -0.0001

SER 25 ASN 26 0.0001

ASN 26 LYS 27 -0.0002

LYS 27 SER 28 0.0005

SER 28 LEU 29 -0.0001

LEU 29 LEU 30 0.0004

LEU 30 HIS 31 -0.0048

HIS 31 SER 32 0.0004

SER 32 ASN 33 0.0004

ASN 33 GLY 34 0.0003

GLY 34 ASN 35 -0.0002

ASN 35 THR 36 -0.0001

THR 36 TYR 37 0.0002

TYR 37 LEU 38 -0.0003

LEU 38 TYR 39 0.0003

TYR 39 TRP 40 0.0003

TRP 40 PHE 41 -0.0002

PHE 41 LEU 42 0.0003

LEU 42 GLN 43 0.0000

GLN 43 ARG 44 0.0001

ARG 44 PRO 45 0.0001

PRO 45 GLY 46 0.0004

GLY 46 GLN 47 -0.0003

GLN 47 SER 48 0.0001

SER 48 PRO 49 0.0002

PRO 49 ARG 50 -0.0001

ARG 50 LEU 51 -0.0003

LEU 51 LEU 52 -0.0002

LEU 52 ILE 53 -0.0002

ILE 53 PHE 54 0.0000

PHE 54 ARG 55 -0.0000

ARG 55 MET 56 -0.0000

MET 56 SER 57 0.0000

SER 57 ASN 58 0.0001

ASN 58 LEU 59 -0.0001

LEU 59 ALA 60 0.0001

ALA 60 SER 61 0.0005

SER 61 GLY 62 0.0003

GLY 62 VAL 63 -0.0000

VAL 63 PRO 64 -0.0002

PRO 64 ASP 65 0.0000

ASP 65 ARG 66 0.0002

ARG 66 PHE 67 -0.0002

PHE 67 SER 68 0.0001

SER 68 GLY 69 -0.0002

GLY 69 SER 70 0.0003

SER 70 GLY 71 0.0002

GLY 71 SER 72 -0.0004

SER 72 GLY 73 -0.0004

GLY 73 THR 74 -0.0002

THR 74 ALA 75 0.0003

ALA 75 PHE 76 0.0004

PHE 76 THR 77 -0.0001

THR 77 LEU 78 0.0003

LEU 78 ARG 79 0.0002

ARG 79 ILE 80 0.0000

ILE 80 SER 81 0.0002

SER 81 ARG 82 0.0000

ARG 82 VAL 83 0.0004

VAL 83 GLU 84 0.0000

GLU 84 ALA 85 -0.0001

ALA 85 ALA 86 0.0003

ALA 86 ASP 87 -0.0002

ASP 87 VAL 88 0.0001

VAL 88 GLY 89 0.0000

GLY 89 ILE 90 -0.0002

ILE 90 TYR 91 0.0025

TYR 91 PHE 92 -0.0003

PHE 92 CYS 93 0.0003

CYS 93 LEU 94 -0.0001

LEU 94 GLN 95 0.0001

GLN 95 HIS 96 -0.0004

HIS 96 LEU 97 -0.0001

LEU 97 GLU 98 0.0000

GLU 98 TYR 99 0.0001

TYR 99 PRO 100 -0.0003

PRO 100 PHE 101 0.0001

PHE 101 THR 102 -0.0001

THR 102 PHE 103 0.0001

PHE 103 GLY 104 -0.0002

GLY 104 ALA 105 -0.0001

ALA 105 GLY 106 0.0049

GLY 106 THR 107 -0.0001

THR 107 LYS 108 0.0001

LYS 108 LEU 109 0.0003

LEU 109 GLU 110 -0.0001

GLU 110 LEU 111 -0.0002

LEU 111 LYS 112 0.0000

LYS 112 ARG 113 0.0000

ARG 113 ALA 114 0.0000

ALA 114 ASP 115 -0.0002

ASP 115 ALA 116 -0.0001

ALA 116 ALA 117 0.0002

ALA 117 PRO 118 -0.0001

PRO 118 THR 119 -0.0000

THR 119 VAL 120 -0.0002

VAL 120 SER 121 -0.0021

SER 121 ILE 122 -0.0000

ILE 122 PHE 123 0.0002

PHE 123 PRO 124 -0.0002

PRO 124 PRO 125 -0.0002

PRO 125 SER 126 0.0003

SER 126 SER 127 0.0001

SER 127 GLU 128 -0.0002

GLU 128 GLN 129 -0.0001

GLN 129 LEU 130 0.0002

LEU 130 THR 131 0.0003

THR 131 SER 132 -0.0003

SER 132 GLY 133 0.0002

GLY 133 GLY 134 -0.0002

GLY 134 ALA 135 0.0000

ALA 135 SER 136 -0.0020

SER 136 VAL 137 -0.0000

VAL 137 VAL 138 -0.0003

VAL 138 CYS 139 0.0001

CYS 139 PHE 140 0.0000

PHE 140 LEU 141 -0.0001

LEU 141 ASN 142 0.0001

ASN 142 ASN 143 -0.0000

ASN 143 PHE 144 -0.0003

PHE 144 TYR 145 0.0003

TYR 145 PRO 146 -0.0003

PRO 146 LYS 147 0.0001

LYS 147 ASP 148 0.0002

ASP 148 ILE 149 -0.0003

ILE 149 ASN 150 0.0000

ASN 150 VAL 151 -0.0016

VAL 151 LYS 152 -0.0002

LYS 152 TRP 153 0.0003

TRP 153 LYS 154 -0.0002

LYS 154 ILE 155 0.0000

ILE 155 ASP 156 0.0000

ASP 156 GLY 157 -0.0002

GLY 157 SER 158 0.0000

SER 158 GLU 159 -0.0002

GLU 159 ARG 160 -0.0002

ARG 160 GLN 161 -0.0000

GLN 161 ASN 162 0.0000

ASN 162 GLY 163 0.0001

GLY 163 VAL 164 0.0000

VAL 164 LEU 165 0.0001

LEU 165 ASN 166 -0.0041

ASN 166 SER 167 -0.0005

SER 167 TRP 168 -0.0002

TRP 168 THR 169 -0.0001

THR 169 ASP 170 -0.0002

ASP 170 GLN 171 -0.0001

GLN 171 ASP 172 0.0002

ASP 172 SER 173 -0.0002

SER 173 LYS 174 0.0004

LYS 174 ASP 175 -0.0004

ASP 175 SER 176 0.0002

SER 176 THR 177 0.0001

THR 177 TYR 178 -0.0001

TYR 178 SER 179 0.0002

SER 179 MET 180 -0.0000

MET 180 SER 181 0.0005

SER 181 SER 182 -0.0001

SER 182 THR 183 0.0001

THR 183 LEU 184 0.0002

LEU 184 THR 185 0.0000

THR 185 LEU 186 0.0000

LEU 186 THR 187 0.0001

THR 187 LYS 188 0.0003

LYS 188 ASP 189 -0.0000

ASP 189 GLU 190 -0.0001

GLU 190 TYR 191 0.0001

TYR 191 GLU 192 0.0003

GLU 192 ARG 193 -0.0003

ARG 193 HIS 194 -0.0004

HIS 194 ASN 195 -0.0002

ASN 195 SER 196 0.0002

SER 196 TYR 197 -0.0001

TYR 197 THR 198 -0.0003

THR 198 CYS 199 -0.0001

CYS 199 GLU 200 0.0000

GLU 200 ALA 201 -0.0000

ALA 201 THR 202 -0.0005

THR 202 HIS 203 0.0000

HIS 203 LYS 204 0.0000

LYS 204 THR 205 -0.0001

THR 205 SER 206 0.0001

SER 206 THR 207 -0.0002

THR 207 SER 208 0.0004

SER 208 PRO 209 0.0003

PRO 209 ILE 210 -0.0000

ILE 210 VAL 211 -0.0009

VAL 211 LYS 212 -0.0000

LYS 212 SER 213 -0.0000

SER 213 PHE 214 0.0006

PHE 214 ASN 215 -0.0001

ASN 215 ARG 216 0.0000

ARG 216 ASN 217 0.0000

ASN 217 GLU 218 -0.0000

GLU 218 CYS 219 -0.0001

CYS 219 GLN 1 0.0070

GLN 1 VAL 2 -0.0002

VAL 2 HIS 3 -0.0002

HIS 3 LEU 4 -0.0002

LEU 4 GLN 5 -0.0000

GLN 5 GLN 6 0.0001

GLN 6 SER 7 0.0002

SER 7 GLY 8 0.0002

GLY 8 ALA 9 0.0001

ALA 9 GLU 10 0.0002

GLU 10 LEU 11 0.0001

LEU 11 MET 12 -0.0000

MET 12 LYS 13 -0.0003

LYS 13 PRO 14 0.0004

PRO 14 GLY 15 -0.0004

GLY 15 ALA 16 0.0045

ALA 16 SER 17 -0.0002

SER 17 VAL 18 0.0002

VAL 18 LYS 19 0.0000

LYS 19 ILE 20 0.0000

ILE 20 SER 21 0.0002

SER 21 CYS 22 -0.0003

CYS 22 LYS 23 0.0001

LYS 23 ALA 24 0.0001

ALA 24 THR 25 0.0001

THR 25 GLY 26 -0.0002

GLY 26 TYR 27 -0.0001

TYR 27 THR 28 0.0001

THR 28 PHE 29 -0.0001

PHE 29 THR 30 0.0001

THR 30 SER 31 -0.0020

SER 31 TYR 32 0.0002

TYR 32 TRP 33 -0.0004

TRP 33 ILE 34 0.0003

ILE 34 GLU 35 -0.0002

GLU 35 TRP 36 -0.0002

TRP 36 VAL 37 0.0002

VAL 37 LYS 38 -0.0001

LYS 38 GLN 39 0.0002

GLN 39 ARG 40 -0.0005

ARG 40 PRO 41 0.0000

PRO 41 GLY 42 -0.0001

GLY 42 HIS 43 -0.0001

HIS 43 GLY 44 0.0000

GLY 44 LEU 45 0.0004

LEU 45 GLU 46 -0.0023

GLU 46 TRP 47 -0.0001

TRP 47 LEU 48 -0.0002

LEU 48 GLY 49 -0.0002

GLY 49 GLU 50 0.0003

GLU 50 ILE 51 -0.0002

ILE 51 LEU 52 0.0000

LEU 52 PRO 53 -0.0004

PRO 53 GLY 54 -0.0001

GLY 54 SER 55 -0.0002

SER 55 GLY 56 -0.0000

GLY 56 TYR 57 0.0000

TYR 57 ILE 58 -0.0001

ILE 58 HIS 59 0.0000

HIS 59 TYR 60 -0.0000

TYR 60 ASN 61 -0.0009

ASN 61 GLU 62 -0.0001

GLU 62 LYS 63 -0.0001

LYS 63 PHE 64 0.0001

PHE 64 LYS 65 -0.0001

LYS 65 GLY 66 0.0000

GLY 66 LYS 67 -0.0003

LYS 67 ALA 68 0.0002

ALA 68 THR 69 -0.0003

THR 69 PHE 70 0.0002

PHE 70 THR 71 -0.0000

THR 71 THR 72 -0.0002

THR 72 ASP 73 0.0001

ASP 73 THR 74 -0.0002

THR 74 SER 75 0.0000

SER 75 SER 76 0.0006

SER 76 ASN 77 -0.0001

ASN 77 THR 78 -0.0004

THR 78 ALA 79 -0.0000

ALA 79 TYR 80 0.0001

TYR 80 MET 81 -0.0001

MET 81 GLN 82 -0.0001

GLN 82 LEU 83 0.0002

LEU 83 SER 84 -0.0003

SER 84 SER 85 -0.0002

SER 85 LEU 86 0.0002

LEU 86 THR 87 0.0003

THR 87 SER 88 -0.0004

SER 88 GLU 89 0.0003

GLU 89 ASP 90 -0.0003

ASP 90 SER 91 0.0040

SER 91 ALA 92 0.0002

ALA 92 VAL 93 -0.0002

VAL 93 TYR 94 0.0003

TYR 94 TYR 95 -0.0000

TYR 95 CYS 96 -0.0003

CYS 96 SER 97 -0.0002

SER 97 ARG 98 0.0003

ARG 98 ALA 99 0.0003

ALA 99 LEU 100 -0.0001

LEU 100 ALA 101 -0.0002

ALA 101 LEU 102 -0.0000

LEU 102 TYR 103 -0.0001

TYR 103 ALA 104 0.0003

ALA 104 MET 105 0.0000

MET 105 ASP 106 0.0025

ASP 106 TYR 107 0.0001

TYR 107 TRP 108 0.0001

TRP 108 GLY 109 -0.0004

GLY 109 GLN 110 0.0003

GLN 110 GLY 111 0.0002

GLY 111 THR 112 -0.0001

THR 112 SER 113 0.0001

SER 113 VAL 114 0.0001

VAL 114 THR 115 -0.0002

THR 115 VAL 116 -0.0002

VAL 116 SER 117 0.0000

SER 117 SER 118 -0.0002

SER 118 ALA 119 0.0001

ALA 119 LYS 120 -0.0001

LYS 120 THR 121 -0.0140

THR 121 THR 122 0.0004

THR 122 PRO 123 -0.0002

PRO 123 PRO 124 0.0003

PRO 124 SER 125 -0.0002

SER 125 VAL 126 0.0002

VAL 126 TYR 127 0.0000

TYR 127 PRO 128 0.0002

PRO 128 LEU 129 -0.0002

LEU 129 ALA 130 -0.0000

ALA 130 PRO 131 0.0001

PRO 131 GLY 132 -0.0002

GLY 132 SER 133 -0.0002

SER 133 ALA 134 -0.0001

ALA 134 ALA 135 -0.0001

ALA 135 GLN 136 0.0013

GLN 136 THR 137 -0.0002

THR 137 ASN 138 -0.0002

ASN 138 SER 139 0.0002

SER 139 MET 140 -0.0001

MET 140 VAL 141 -0.0001

VAL 141 THR 142 0.0000

THR 142 LEU 143 0.0002

LEU 143 GLY 144 0.0001

GLY 144 CYS 145 -0.0001

CYS 145 LEU 146 -0.0001

LEU 146 VAL 147 0.0001

VAL 147 LYS 148 0.0000

LYS 148 GLY 149 -0.0000

GLY 149 TYR 150 -0.0001

TYR 150 PHE 151 0.0038

PHE 151 PRO 152 -0.0005

PRO 152 GLU 153 -0.0000

GLU 153 PRO 154 0.0000

PRO 154 VAL 155 0.0006

VAL 155 THR 156 0.0002

THR 156 VAL 157 0.0001

VAL 157 THR 158 -0.0003

THR 158 TRP 159 0.0000

TRP 159 ASN 160 0.0002

ASN 160 SER 161 0.0000

SER 161 GLY 162 0.0004

GLY 162 SER 163 -0.0004

SER 163 LEU 164 0.0002

LEU 164 SER 165 -0.0001

SER 165 SER 166 -0.0022

SER 166 GLY 167 0.0002

GLY 167 VAL 168 -0.0000

VAL 168 HIS 169 0.0003

HIS 169 THR 170 0.0004

THR 170 PHE 171 0.0001

PHE 171 PRO 172 0.0001

PRO 172 ALA 173 0.0002

ALA 173 VAL 174 -0.0001

VAL 174 LEU 175 -0.0003

LEU 175 GLN 176 -0.0001

GLN 176 SER 177 0.0001

SER 177 ASP 178 0.0001

ASP 178 LEU 179 0.0002

LEU 179 TYR 180 -0.0001

TYR 180 THR 181 -0.0001

THR 181 LEU 182 0.0003

LEU 182 SER 183 -0.0005

SER 183 SER 184 0.0002

SER 184 SER 185 0.0000

SER 185 VAL 186 -0.0000

VAL 186 THR 187 -0.0000

THR 187 VAL 188 0.0002

VAL 188 PRO 189 -0.0001

PRO 189 SER 190 0.0001

SER 190 SER 191 0.0002

SER 191 THR 192 -0.0001

THR 192 TRP 193 0.0002

TRP 193 PRO 194 -0.0003

PRO 194 SER 195 0.0002

SER 195 GLU 196 -0.0003

GLU 196 THR 197 -0.0001

THR 197 VAL 198 -0.0003

VAL 198 THR 199 0.0000

THR 199 CYS 200 -0.0000

CYS 200 ASN 201 -0.0003

ASN 201 VAL 202 -0.0001

VAL 202 ALA 203 0.0000

ALA 203 HIS 204 0.0002

HIS 204 PRO 205 -0.0003

PRO 205 ALA 206 -0.0002

ALA 206 SER 207 -0.0003

SER 207 SER 208 0.0001

SER 208 THR 209 -0.0000

THR 209 LYS 210 -0.0000

LYS 210 VAL 211 0.0011

VAL 211 ASP 212 -0.0003

ASP 212 LYS 213 0.0003

LYS 213 LYS 214 0.0002

LYS 214 ILE 215 -0.0001

ILE 215 VAL 216 -0.0001

VAL 216 PRO 217 0.0001

PRO 217 ARG 218 -0.0002

ARG 218 ASP 1 0.0305

ASP 1 ILE 2 0.0002

ILE 2 VAL 3 0.0002

VAL 3 MET 4 0.0004

MET 4 THR 5 0.0001

THR 5 GLN 6 -0.0000

GLN 6 ALA 7 -0.0001

ALA 7 THR 8 0.0004

THR 8 PRO 9 -0.0002

PRO 9 SER 10 -0.0001

SER 10 ILE 11 0.0002

ILE 11 PRO 12 -0.0001

PRO 12 VAL 13 -0.0002

VAL 13 THR 14 0.0000

THR 14 PRO 15 0.0000

PRO 15 GLY 16 -0.0070

GLY 16 GLU 17 -0.0003

GLU 17 SER 18 0.0002

SER 18 VAL 19 0.0000

VAL 19 SER 20 0.0001

SER 20 ILE 21 -0.0000

ILE 21 SER 22 -0.0001

SER 22 CYS 23 0.0000

CYS 23 ARG 24 0.0002

ARG 24 SER 25 -0.0003

SER 25 ASN 26 0.0002

ASN 26 LYS 27 0.0002

LYS 27 SER 28 -0.0002

SER 28 LEU 29 -0.0002

LEU 29 LEU 30 0.0004

LEU 30 HIS 31 -0.0091

HIS 31 SER 32 -0.0001

SER 32 ASN 33 -0.0002

ASN 33 GLY 34 0.0000

GLY 34 ASN 35 -0.0004

ASN 35 THR 36 0.0001

THR 36 TYR 37 -0.0001

TYR 37 LEU 38 -0.0002

LEU 38 TYR 39 0.0003

TYR 39 TRP 40 0.0001

TRP 40 PHE 41 0.0002

PHE 41 LEU 42 -0.0000

LEU 42 GLN 43 -0.0000

GLN 43 ARG 44 -0.0001

ARG 44 PRO 45 -0.0002

PRO 45 GLY 46 0.0059

GLY 46 GLN 47 0.0004

GLN 47 SER 48 -0.0002

SER 48 PRO 49 -0.0002

PRO 49 ARG 50 0.0001

ARG 50 LEU 51 -0.0002

LEU 51 LEU 52 0.0003

LEU 52 ILE 53 0.0002

ILE 53 PHE 54 0.0000

PHE 54 ARG 55 -0.0004

ARG 55 MET 56 0.0001

MET 56 SER 57 0.0001

SER 57 ASN 58 -0.0000

ASN 58 LEU 59 0.0002

LEU 59 ALA 60 0.0002

ALA 60 SER 61 -0.0043

SER 61 GLY 62 0.0002

GLY 62 VAL 63 0.0000

VAL 63 PRO 64 0.0003

PRO 64 ASP 65 -0.0000

ASP 65 ARG 66 0.0002

ARG 66 PHE 67 0.0000

PHE 67 SER 68 0.0001

SER 68 GLY 69 0.0001

GLY 69 SER 70 -0.0003

SER 70 GLY 71 0.0000

GLY 71 SER 72 -0.0002

SER 72 GLY 73 0.0001

GLY 73 THR 74 -0.0000

THR 74 ALA 75 0.0001

ALA 75 PHE 76 -0.0046

PHE 76 THR 77 0.0001

THR 77 LEU 78 0.0002

LEU 78 ARG 79 0.0003

ARG 79 ILE 80 0.0002

ILE 80 SER 81 0.0001

SER 81 ARG 82 0.0002

ARG 82 VAL 83 -0.0002

VAL 83 GLU 84 0.0003

GLU 84 ALA 85 0.0005

ALA 85 ALA 86 -0.0002

ALA 86 ASP 87 0.0001

ASP 87 VAL 88 -0.0001

VAL 88 GLY 89 -0.0002

GLY 89 ILE 90 -0.0003

ILE 90 TYR 91 -0.0017

TYR 91 PHE 92 0.0001

PHE 92 CYS 93 -0.0001

CYS 93 LEU 94 0.0004

LEU 94 GLN 95 -0.0002

GLN 95 HIS 96 -0.0003

HIS 96 LEU 97 -0.0003

LEU 97 GLU 98 0.0001

GLU 98 TYR 99 -0.0002

TYR 99 PRO 100 0.0003

PRO 100 PHE 101 -0.0002

PHE 101 THR 102 0.0002

THR 102 PHE 103 0.0001

PHE 103 GLY 104 0.0000

GLY 104 ALA 105 0.0001

ALA 105 GLY 106 0.0046

GLY 106 THR 107 0.0003

THR 107 LYS 108 0.0001

LYS 108 LEU 109 -0.0000

LEU 109 GLU 110 -0.0003

GLU 110 LEU 111 0.0004

LEU 111 LYS 112 -0.0000

LYS 112 ARG 113 -0.0002

ARG 113 ALA 114 0.0001

ALA 114 ASP 115 0.0004

ASP 115 ALA 116 -0.0001

ALA 116 ALA 117 0.0001

ALA 117 PRO 118 -0.0003

PRO 118 THR 119 -0.0002

THR 119 VAL 120 0.0005

VAL 120 SER 121 -0.0001

SER 121 ILE 122 -0.0002

ILE 122 PHE 123 -0.0001

PHE 123 PRO 124 0.0002

PRO 124 PRO 125 -0.0000

PRO 125 SER 126 0.0003

SER 126 SER 127 0.0001

SER 127 GLU 128 0.0002

GLU 128 GLN 129 0.0002

GLN 129 LEU 130 0.0001

LEU 130 THR 131 0.0002

THR 131 SER 132 0.0002

SER 132 GLY 133 -0.0002

GLY 133 GLY 134 0.0001

GLY 134 ALA 135 0.0001

ALA 135 SER 136 0.0008

SER 136 VAL 137 0.0001

VAL 137 VAL 138 -0.0002

VAL 138 CYS 139 -0.0001

CYS 139 PHE 140 0.0001

PHE 140 LEU 141 0.0002

LEU 141 ASN 142 0.0002

ASN 142 ASN 143 -0.0003

ASN 143 PHE 144 -0.0000

PHE 144 TYR 145 -0.0002

TYR 145 PRO 146 -0.0001

PRO 146 LYS 147 -0.0002

LYS 147 ASP 148 0.0002

ASP 148 ILE 149 -0.0003

ILE 149 ASN 150 0.0001

ASN 150 VAL 151 0.0021

VAL 151 LYS 152 -0.0001

LYS 152 TRP 153 -0.0001

TRP 153 LYS 154 0.0004

LYS 154 ILE 155 -0.0003

ILE 155 ASP 156 0.0001

ASP 156 GLY 157 -0.0001

GLY 157 SER 158 0.0003

SER 158 GLU 159 0.0001

GLU 159 ARG 160 0.0001

ARG 160 GLN 161 0.0001

GLN 161 ASN 162 0.0002

ASN 162 GLY 163 -0.0004

GLY 163 VAL 164 0.0002

VAL 164 LEU 165 0.0003

LEU 165 ASN 166 0.0013

ASN 166 SER 167 0.0002

SER 167 TRP 168 -0.0003

TRP 168 THR 169 -0.0000

THR 169 ASP 170 -0.0001

ASP 170 GLN 171 -0.0002

GLN 171 ASP 172 0.0001

ASP 172 SER 173 -0.0003

SER 173 LYS 174 -0.0001

LYS 174 ASP 175 0.0001

ASP 175 SER 176 -0.0000

SER 176 THR 177 -0.0004

THR 177 TYR 178 0.0006

TYR 178 SER 179 0.0001

SER 179 MET 180 0.0003

MET 180 SER 181 -0.0014

SER 181 SER 182 0.0003

SER 182 THR 183 -0.0001

THR 183 LEU 184 -0.0000

LEU 184 THR 185 -0.0002

THR 185 LEU 186 -0.0001

LEU 186 THR 187 -0.0001

THR 187 LYS 188 0.0004

LYS 188 ASP 189 0.0003

ASP 189 GLU 190 0.0002

GLU 190 TYR 191 0.0000

TYR 191 GLU 192 0.0002

GLU 192 ARG 193 0.0003

ARG 193 HIS 194 -0.0004

HIS 194 ASN 195 0.0001

ASN 195 SER 196 0.0004

SER 196 TYR 197 0.0000

TYR 197 THR 198 -0.0002

THR 198 CYS 199 0.0004

CYS 199 GLU 200 0.0001

GLU 200 ALA 201 0.0000

ALA 201 THR 202 0.0001

THR 202 HIS 203 0.0002

HIS 203 LYS 204 -0.0000

LYS 204 THR 205 0.0003

THR 205 SER 206 -0.0002

SER 206 THR 207 -0.0001

THR 207 SER 208 -0.0000

SER 208 PRO 209 0.0001

PRO 209 ILE 210 0.0002

ILE 210 VAL 211 0.0007

VAL 211 LYS 212 -0.0001

LYS 212 SER 213 -0.0001

SER 213 PHE 214 0.0003

PHE 214 ASN 215 -0.0002

ASN 215 ARG 216 0.0002

ARG 216 ASN 217 0.0000

ASN 217 GLU 218 0.0003

GLU 218 CYS 219 0.0001

CYS 219 GLN 1 -0.0012

GLN 1 VAL 2 -0.0002

VAL 2 HIS 3 0.0000

HIS 3 LEU 4 -0.0001

LEU 4 GLN 5 -0.0001

GLN 5 GLN 6 -0.0003

GLN 6 SER 7 0.0005

SER 7 GLY 8 -0.0001

GLY 8 ALA 9 0.0003

ALA 9 GLU 10 -0.0001

GLU 10 LEU 11 -0.0003

LEU 11 MET 12 0.0000

MET 12 LYS 13 -0.0002

LYS 13 PRO 14 0.0003

PRO 14 GLY 15 -0.0002

GLY 15 ALA 16 0.0017

ALA 16 SER 17 -0.0002

SER 17 VAL 18 0.0001

VAL 18 LYS 19 -0.0000

LYS 19 ILE 20 0.0002

ILE 20 SER 21 0.0002

SER 21 CYS 22 -0.0001

CYS 22 LYS 23 0.0002

LYS 23 ALA 24 -0.0002

ALA 24 THR 25 -0.0003

THR 25 GLY 26 -0.0002

GLY 26 TYR 27 -0.0001

TYR 27 THR 28 0.0001

THR 28 PHE 29 -0.0001

PHE 29 THR 30 0.0002

THR 30 SER 31 0.0018

SER 31 TYR 32 0.0002

TYR 32 TRP 33 0.0003

TRP 33 ILE 34 0.0000

ILE 34 GLU 35 0.0004

GLU 35 TRP 36 -0.0003

TRP 36 VAL 37 -0.0001

VAL 37 LYS 38 0.0001

LYS 38 GLN 39 0.0005

GLN 39 ARG 40 -0.0005

ARG 40 PRO 41 -0.0002

PRO 41 GLY 42 -0.0000

GLY 42 HIS 43 0.0000

HIS 43 GLY 44 -0.0003

GLY 44 LEU 45 -0.0002

LEU 45 GLU 46 0.0014

GLU 46 TRP 47 0.0004

TRP 47 LEU 48 -0.0006

LEU 48 GLY 49 0.0002

GLY 49 GLU 50 -0.0002

GLU 50 ILE 51 0.0001

ILE 51 LEU 52 -0.0002

LEU 52 PRO 53 -0.0001

PRO 53 GLY 54 0.0002

GLY 54 SER 55 -0.0002

SER 55 GLY 56 -0.0000

GLY 56 TYR 57 -0.0001

TYR 57 ILE 58 0.0005

ILE 58 HIS 59 0.0001

HIS 59 TYR 60 0.0000

TYR 60 ASN 61 0.0007

ASN 61 GLU 62 0.0004

GLU 62 LYS 63 0.0002

LYS 63 PHE 64 0.0001

PHE 64 LYS 65 -0.0004

LYS 65 GLY 66 0.0002

GLY 66 LYS 67 0.0002

LYS 67 ALA 68 0.0001

ALA 68 THR 69 -0.0005

THR 69 PHE 70 0.0002

PHE 70 THR 71 -0.0001

THR 71 THR 72 -0.0004

THR 72 ASP 73 0.0000

ASP 73 THR 74 0.0002

THR 74 SER 75 -0.0001

SER 75 SER 76 0.0008

SER 76 ASN 77 -0.0000

ASN 77 THR 78 -0.0001

THR 78 ALA 79 0.0000

ALA 79 TYR 80 0.0000

TYR 80 MET 81 0.0002

MET 81 GLN 82 -0.0001

GLN 82 LEU 83 -0.0000

LEU 83 SER 84 0.0001

SER 84 SER 85 0.0005

SER 85 LEU 86 0.0001

LEU 86 THR 87 -0.0003

THR 87 SER 88 0.0001

SER 88 GLU 89 0.0004

GLU 89 ASP 90 0.0002

ASP 90 SER 91 -0.0037

SER 91 ALA 92 -0.0001

ALA 92 VAL 93 -0.0002

VAL 93 TYR 94 -0.0002

TYR 94 TYR 95 0.0002

TYR 95 CYS 96 0.0002

CYS 96 SER 97 0.0003

SER 97 ARG 98 -0.0002

ARG 98 ALA 99 -0.0001

ALA 99 LEU 100 0.0003

LEU 100 ALA 101 -0.0001

ALA 101 LEU 102 -0.0001

LEU 102 TYR 103 -0.0001

TYR 103 ALA 104 0.0000

ALA 104 MET 105 -0.0002

MET 105 ASP 106 -0.0032

ASP 106 TYR 107 -0.0002

TYR 107 TRP 108 0.0003

TRP 108 GLY 109 -0.0004

GLY 109 GLN 110 0.0001

GLN 110 GLY 111 -0.0002

GLY 111 THR 112 -0.0001

THR 112 SER 113 -0.0002

SER 113 VAL 114 -0.0001

VAL 114 THR 115 0.0003

THR 115 VAL 116 0.0003

VAL 116 SER 117 -0.0002

SER 117 SER 118 -0.0003

SER 118 ALA 119 -0.0003

ALA 119 LYS 120 0.0002

LYS 120 THR 121 0.0112

THR 121 THR 122 -0.0001

THR 122 PRO 123 0.0000

PRO 123 PRO 124 0.0001

PRO 124 SER 125 0.0001

SER 125 VAL 126 0.0000

VAL 126 TYR 127 0.0002

TYR 127 PRO 128 -0.0001

PRO 128 LEU 129 -0.0002

LEU 129 ALA 130 0.0000

ALA 130 PRO 131 0.0002

PRO 131 GLY 132 -0.0002

GLY 132 SER 133 0.0000

SER 133 ALA 134 0.0001

ALA 134 ALA 135 0.0001

ALA 135 GLN 136 -0.0016

GLN 136 THR 137 0.0001

THR 137 ASN 138 0.0001

ASN 138 SER 139 0.0003

SER 139 MET 140 0.0002

MET 140 VAL 141 0.0000

VAL 141 THR 142 -0.0000

THR 142 LEU 143 -0.0002

LEU 143 GLY 144 0.0000

GLY 144 CYS 145 -0.0002

CYS 145 LEU 146 -0.0001

LEU 146 VAL 147 0.0000

VAL 147 LYS 148 -0.0001

LYS 148 GLY 149 -0.0001

GLY 149 TYR 150 0.0002

TYR 150 PHE 151 0.0004

PHE 151 PRO 152 -0.0002

PRO 152 GLU 153 -0.0000

GLU 153 PRO 154 0.0000

PRO 154 VAL 155 0.0002

VAL 155 THR 156 0.0001

THR 156 VAL 157 -0.0000

VAL 157 THR 158 0.0004

THR 158 TRP 159 -0.0004

TRP 159 ASN 160 0.0003

ASN 160 SER 161 -0.0002

SER 161 GLY 162 0.0002

GLY 162 SER 163 0.0003

SER 163 LEU 164 -0.0000

LEU 164 SER 165 -0.0000

SER 165 SER 166 -0.0022

SER 166 GLY 167 -0.0002

GLY 167 VAL 168 -0.0005

VAL 168 HIS 169 0.0001

HIS 169 THR 170 0.0001

THR 170 PHE 171 -0.0002

PHE 171 PRO 172 0.0003

PRO 172 ALA 173 0.0001

ALA 173 VAL 174 0.0001

VAL 174 LEU 175 -0.0002

LEU 175 GLN 176 -0.0001

GLN 176 SER 177 0.0001

SER 177 ASP 178 -0.0002

ASP 178 LEU 179 0.0001

LEU 179 TYR 180 0.0003

TYR 180 THR 181 0.0019

THR 181 LEU 182 0.0001

LEU 182 SER 183 0.0001

SER 183 SER 184 -0.0005

SER 184 SER 185 -0.0002

SER 185 VAL 186 0.0001

VAL 186 THR 187 -0.0002

THR 187 VAL 188 0.0003

VAL 188 PRO 189 -0.0004

PRO 189 SER 190 -0.0001

SER 190 SER 191 0.0004

SER 191 THR 192 -0.0004

THR 192 TRP 193 -0.0001

TRP 193 PRO 194 -0.0005

PRO 194 SER 195 0.0004

SER 195 GLU 196 0.0008

GLU 196 THR 197 0.0000

THR 197 VAL 198 -0.0001

VAL 198 THR 199 0.0004

THR 199 CYS 200 -0.0001

CYS 200 ASN 201 0.0003

ASN 201 VAL 202 0.0004

VAL 202 ALA 203 -0.0000

ALA 203 HIS 204 -0.0001

HIS 204 PRO 205 -0.0004

PRO 205 ALA 206 -0.0001

ALA 206 SER 207 0.0002

SER 207 SER 208 -0.0001

SER 208 THR 209 0.0001

THR 209 LYS 210 -0.0000

LYS 210 VAL 211 0.0002

VAL 211 ASP 212 -0.0002

ASP 212 LYS 213 0.0003

LYS 213 LYS 214 -0.0003

LYS 214 ILE 215 0.0001

ILE 215 VAL 216 -0.0001

VAL 216 PRO 217 -0.0000

PRO 217 ARG 218 0.0004

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.

Should you encounter any unexpected behaviour, please let us know. elNémo has been relocated. **Some cleaning from time to time** Sorry for the inconvenience.

*** CELL ADHESION/IMMUNE SYSTEM 21-SEP-11 3VI3 ***

CA strain for 260522123717486593

--- normal mode 10 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* CELL ADHESION/IMMUNE SYSTEM 21-SEP-11 3VI3 *