Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* HYDROLASE 21-FEB-23 8CMV *

CA distance fluctuations for 2606131810021463505

--- normal mode 9 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
THR 229 0.92 ASP 36 -0.79 GLY 81

ARG 290 0.78 ASN 37 -0.54 GLY 42

LYS 293 0.37 PRO 38 -0.43 LEU 84

HIS 291 0.23 TYR 39 -0.21 GLY 113

HIS 291 0.22 ARG 40 -0.37 ASN 37

LYS 293 0.17 ARG 41 -0.45 ASN 37

THR 82 0.23 GLY 42 -0.60 ASP 36

THR 82 0.22 PRO 43 -0.60 ASP 36

THR 82 0.19 ASN 44 -0.38 ASP 36

THR 82 0.20 PRO 45 -0.27 ASP 36

PRO 55 0.20 THR 46 -0.24 ASP 36

PHE 56 0.16 ARG 47 -0.14 ASP 36

PHE 56 0.15 ASP 48 -0.26 ASP 36

PHE 56 0.15 ASP 48 -0.26 ASP 36

PRO 55 0.20 ALA 49 -0.36 ASP 36

PHE 56 0.16 LEU 50 -0.24 ASP 36

LYS 57 0.12 THR 51 -0.24 ASP 36

LYS 57 0.11 ALA 52 -0.37 ASP 36

LYS 57 0.14 ASP 53 -0.45 ASP 36

ALA 49 0.20 GLY 54 -0.51 ASP 36

THR 46 0.20 PRO 55 -0.67 ASP 36

ALA 49 0.20 PHE 56 -0.65 ASP 36

ALA 49 0.19 LYS 57 -0.64 ASP 36

ASP 53 0.11 VAL 58 -0.53 ASP 36

ALA 49 0.09 ALA 59 -0.49 ASP 36

THR 46 0.05 THR 60 -0.40 ASP 36

THR 46 0.04 TYR 61 -0.33 ASP 36

LEU 142 0.04 THR 62 -0.27 ASP 36

LEU 142 0.06 VAL 63 -0.19 ASP 36

TYR 141 0.08 SER 64 -0.18 ILE 243

ALA 138 0.12 ARG 65 -0.21 ILE 243

VAL 68 0.20 LEU 66 -0.21 VAL 212

TYR 141 0.18 SER 67 -0.17 VAL 212

LEU 66 0.20 VAL 68 -0.17 VAL 212

ASN 140 0.20 SER 69 -0.18 VAL 212

ALA 137 0.14 GLY 70 -0.17 VAL 212

ASN 37 0.10 PHE 71 -0.19 VAL 212

ALA 138 0.11 GLY 72 -0.21 VAL 212

ALA 138 0.10 GLY 73 -0.17 ILE 243

ALA 138 0.04 GLY 74 -0.17 ILE 243

ALA 90 0.03 VAL 75 -0.22 ASP 36

TRP 263 0.04 ILE 76 -0.25 ASP 36

ALA 49 0.04 TYR 77 -0.33 ASP 36

ALA 49 0.09 TYR 78 -0.39 ASP 36

ALA 49 0.13 PRO 79 -0.53 ASP 36

THR 46 0.15 THR 80 -0.63 ASP 36

THR 46 0.18 GLY 81 -0.79 ASP 36

GLY 42 0.23 THR 82 -0.78 ASP 36

GLY 42 0.22 SER 83 -0.74 ASP 36

GLY 42 0.21 LEU 84 -0.62 ASP 36

GLY 42 0.16 THR 85 -0.39 ASP 36

GLY 42 0.13 PHE 86 -0.26 PRO 38

THR 144 0.10 GLY 87 -0.12 PRO 38

SER 69 0.08 GLY 88 -0.10 PRO 38

ASN 37 0.09 ILE 89 -0.07 TYR 39

ASN 37 0.10 ALA 90 -0.07 ARG 41

ASN 37 0.09 MET 91 -0.09 ARG 41

ASN 37 0.09 MET 91 -0.09 ARG 41

ASN 37 0.10 SER 92 -0.11 SER 241

SER 100 0.07 PRO 93 -0.19 ILE 243

ASN 37 0.09 GLY 94 -0.19 VAL 212

ASN 37 0.10 TYR 95 -0.35 VAL 212

ASP 129 0.09 THR 96 -0.41 VAL 212

ASP 129 0.06 ALA 97 -0.38 ILE 243

ALA 132 0.06 ASP 98 -0.28 ILE 243

ALA 90 0.04 ALA 99 -0.21 ILE 243

PRO 93 0.07 SER 100 -0.19 ASP 36

GLY 167 0.05 SER 101 -0.23 ILE 243

GLY 163 0.03 LEU 102 -0.14 ARG 41

MET 91 0.03 ALA 103 -0.23 ASP 36

GLY 168 0.03 TRP 104 -0.26 ASP 36

TRP 190 0.03 LEU 105 -0.19 ASP 36

ALA 90 0.02 GLY 106 -0.22 ASP 36

ALA 149 0.03 ARG 107 -0.34 ASP 36

VAL 58 0.06 ARG 108 -0.31 ASP 36

ALA 110 0.07 LEU 109 -0.24 ASP 36

LYS 278 0.07 ALA 110 -0.35 ASP 36

ALA 49 0.11 SER 111 -0.47 ASP 36

PHE 56 0.17 HIS 112 -0.40 ASP 36

LYS 278 0.11 GLY 113 -0.39 ASP 36

LYS 278 0.08 PHE 114 -0.25 ASP 36

THR 46 0.06 VAL 115 -0.24 ASP 36

TRP 263 0.04 VAL 116 -0.17 ASP 36

VAL 264 0.05 LEU 117 -0.12 ASP 36

ASN 266 0.04 VAL 118 -0.12 ILE 243

ASN 266 0.05 ILE 119 -0.14 ILE 243

ALA 138 0.05 ASN 120 -0.21 ILE 243

ASN 37 0.08 THR 121 -0.22 VAL 212

SER 133 0.10 ASN 122 -0.23 VAL 212

SER 133 0.12 SER 123 -0.28 VAL 212

ASP 126 0.12 ARG 124 -0.31 VAL 212

ASP 126 0.18 PHE 125 -0.35 VAL 212

PHE 125 0.18 ASP 126 -0.26 VAL 212

ASP 36 0.18 GLY 127 -0.21 VAL 212

ASP 36 0.22 PRO 128 -0.15 GLY 70

ASP 36 0.26 ASP 129 -0.14 GLY 70

ASP 36 0.20 SER 130 -0.16 GLY 70

ASN 37 0.18 ARG 131 -0.15 VAL 212

ASP 36 0.23 ALA 132 -0.10 GLY 170

ASP 36 0.22 SER 133 -0.14 ASP 129

ASP 36 0.22 SER 133 -0.14 ASP 129

ASN 37 0.16 GLN 134 -0.14 VAL 212

ASN 37 0.18 LEU 135 -0.10 ALA 138

ASN 37 0.23 SER 136 -0.10 SER 136

ASN 37 0.23 SER 136 -0.10 SER 136

ASN 37 0.17 ALA 137 -0.13 ASP 129

LEU 66 0.13 ALA 138 -0.11 VAL 212

ASN 37 0.16 LEU 139 -0.07 VAL 212

SER 69 0.19 ASN 140 -0.10 ASP 129

SER 69 0.20 ASN 140 -0.10 ASP 129

SER 67 0.18 TYR 141 -0.11 ASP 129

SER 67 0.15 LEU 142 -0.08 VAL 212

SER 67 0.15 LEU 142 -0.08 VAL 212

SER 67 0.15 ARG 143 -0.07 ASP 129

ALA 156 0.16 THR 144 -0.10 ASP 129

SER 67 0.16 ARG 145 -0.12 ASP 129

SER 67 0.12 SER 146 -0.16 ASP 36

GLY 42 0.07 PRO 147 -0.26 ASP 36

GLY 42 0.10 SER 148 -0.32 ASP 36

GLY 42 0.10 SER 148 -0.32 ASP 36

THR 46 0.11 ALA 149 -0.41 ASP 36

THR 46 0.09 VAL 150 -0.33 ASP 36

GLY 42 0.11 ARG 151 -0.25 ASP 36

GLY 42 0.13 ALA 152 -0.37 ASP 36

GLY 42 0.15 ARG 153 -0.39 ASP 36

GLY 42 0.12 LEU 154 -0.21 ASP 36

THR 144 0.13 ASP 155 -0.12 PRO 38

THR 144 0.16 ALA 156 -0.04 GLN 177

ASN 37 0.26 ASN 157 -0.04 GLY 88

ASN 37 0.28 ARG 158 -0.04 GLY 88

ASN 37 0.24 LEU 159 -0.02 ALA 156

ASN 37 0.27 ALA 160 -0.05 LEU 181

ASN 37 0.22 VAL 161 -0.04 ARG 41

ASN 37 0.18 ALA 162 -0.06 ARG 41

ASN 37 0.14 GLY 163 -0.08 VAL 205

ASN 37 0.12 HIS 164 -0.14 PRO 93

ASN 37 0.15 SER 165 -0.16 THR 188

ASN 37 0.17 MET 166 -0.17 ALA 213

ASN 37 0.16 GLY 167 -0.13 PHE 71

ASN 37 0.21 GLY 168 -0.09 PHE 71

ASP 36 0.26 GLY 169 -0.10 PHE 71

ASP 36 0.24 GLY 170 -0.10 ALA 132

ASN 37 0.27 THR 171 -0.07 ALA 138

ASP 36 0.37 LEU 172 -0.06 ALA 138

ASP 36 0.37 ARG 173 -0.08 ASN 140

ASP 36 0.34 ILE 174 -0.06 ASN 140

ASP 36 0.43 ALA 175 -0.04 ASN 178

ASP 36 0.49 GLU 176 -0.04 SER 146

ASP 36 0.44 GLN 177 -0.06 ARG 143

ASP 36 0.44 ASN 178 -0.04 SER 148

ASP 36 0.56 PRO 179 -0.05 ALA 184

ASP 36 0.49 SER 180 -0.05 ALA 183

ASN 37 0.43 LEU 181 -0.05 ALA 160

ASN 37 0.49 LYS 182 -0.03 ARG 271

ASN 37 0.42 ALA 183 -0.05 SER 180

ASN 37 0.35 ALA 184 -0.05 PRO 179

ASN 37 0.26 VAL 185 -0.06 VAL 233

ASN 37 0.25 PRO 186 -0.07 TYR 234

ASN 37 0.18 LEU 187 -0.11 THR 96

ASN 37 0.19 THR 188 -0.20 THR 96

ASP 36 0.22 PRO 189 -0.14 MET 166

ASP 36 0.24 TRP 190 -0.15 GLY 127

ASP 36 0.29 HIS 191 -0.12 GLY 127

ASP 36 0.32 THR 192 -0.13 SER 69

ASP 36 0.39 ASP 193 -0.10 GLY 70

ASP 36 0.43 LYS 194 -0.08 PHE 71

ASP 36 0.51 THR 195 -0.06 LYS 278

ASP 36 0.51 PHE 196 -0.05 LYS 278

ASP 36 0.60 ASN 197 -0.05 LYS 278

ASP 36 0.61 THR 198 -0.04 LYS 278

ASP 36 0.71 SER 199 -0.04 ASP 276

ASP 36 0.58 VAL 200 -0.04 ASP 276

ASN 37 0.58 PRO 201 -0.05 CYS 292

ASN 37 0.46 VAL 202 -0.05 ASP 276

ASN 37 0.38 LEU 203 -0.06 VAL 233

ASN 37 0.32 ILE 204 -0.10 THR 96

ASN 37 0.24 VAL 205 -0.14 THR 96

ASN 37 0.24 GLY 206 -0.20 THR 96

ASN 37 0.18 ALA 207 -0.26 THR 96

ASP 36 0.21 GLU 208 -0.26 THR 96

ASN 37 0.16 ARG 209 -0.32 THR 96

ASN 37 0.17 ASP 210 -0.34 THR 96

ASP 36 0.16 THR 211 -0.38 THR 96

ASN 37 0.15 VAL 212 -0.41 THR 96

ASP 36 0.21 ALA 213 -0.29 THR 96

ASP 36 0.25 PRO 214 -0.27 THR 96

ASP 36 0.30 VAL 215 -0.22 THR 96

ASP 36 0.35 SER 216 -0.19 THR 96

ASP 36 0.35 SER 216 -0.19 THR 96

ASP 36 0.34 GLN 217 -0.18 THR 96

ASP 36 0.33 HIS 218 -0.15 THR 96

ASP 36 0.34 ALA 219 -0.15 THR 96

ASP 36 0.41 ILE 220 -0.14 THR 96

ASP 36 0.46 PRO 221 -0.11 THR 96

ASP 36 0.45 PHE 222 -0.08 THR 96

ASP 36 0.50 TYR 223 -0.09 THR 96

ASP 36 0.57 GLN 224 -0.09 THR 96

ASP 36 0.58 ASN 225 -0.07 LYS 278

ASP 36 0.62 LEU 226 -0.07 LYS 278

ASP 36 0.74 PRO 227 -0.06 LYS 278

ASP 36 0.82 SER 228 -0.09 LYS 278

ASP 36 0.82 SER 228 -0.09 LYS 278

ASP 36 0.92 THR 229 -0.07 ASP 276

ASP 36 0.78 THR 230 -0.06 ASP 276

ASP 36 0.73 PRO 231 -0.07 ASP 276

ASP 36 0.59 LYS 232 -0.06 LYS 278

ASP 36 0.48 VAL 233 -0.09 THR 96

ASP 36 0.40 TYR 234 -0.12 THR 96

ASP 36 0.29 VAL 235 -0.15 THR 96

ASP 36 0.25 GLU 236 -0.19 THR 96

ASN 37 0.18 LEU 237 -0.21 THR 96

ASN 37 0.17 CYS 238 -0.23 THR 96

ASN 37 0.13 ASN 239 -0.28 THR 96

ASN 37 0.13 ASN 239 -0.28 THR 96

ASN 37 0.11 ALA 240 -0.29 THR 96

ASN 37 0.11 SER 241 -0.36 THR 96

ASN 37 0.12 HIS 242 -0.36 THR 96

ASN 266 0.07 ILE 243 -0.38 ALA 97

ASN 266 0.07 ALA 244 -0.25 ALA 97

ASN 266 0.06 PRO 245 -0.20 ALA 97

HIS 164 0.06 ASN 246 -0.19 SER 101

TRP 190 0.05 SER 247 -0.16 ASP 36

TRP 190 0.04 ASN 248 -0.20 ASP 36

ASN 266 0.05 ASN 249 -0.13 ALA 97

LYS 57 0.07 ALA 250 -0.12 ASP 36

ASN 266 0.08 ALA 251 -0.12 THR 96

ASN 266 0.08 ILE 252 -0.11 ALA 97

LYS 57 0.08 SER 253 -0.10 ARG 41

PHE 56 0.12 VAL 254 -0.08 ALA 97

ASN 37 0.17 TYR 255 -0.08 THR 96

ASN 37 0.13 THR 256 -0.06 ARG 41

PHE 56 0.11 ILE 257 -0.09 ARG 41

ASN 37 0.16 SER 258 -0.07 TYR 270

ASN 37 0.31 TRP 259 -0.05 ARG 271

ASN 37 0.21 MET 260 -0.03 ARG 271

ASN 37 0.15 LYS 261 -0.04 LEU 109

ASN 37 0.42 LEU 262 -0.04 ARG 271

ASN 37 0.54 TRP 263 -0.03 ARG 271

ASN 37 0.32 VAL 264 -0.03 THR 268

ASN 37 0.23 ASP 265 -0.04 ASN 266

ASN 37 0.56 ASN 266 -0.04 ASP 265

HIS 291 0.29 ASP 267 -0.06 ASP 53

ASN 37 0.43 THR 268 -0.05 ASP 53

LYS 278 0.20 ARG 269 -0.08 ALA 52

ASN 37 0.20 TYR 270 -0.07 SER 258

ASN 37 0.39 ARG 271 -0.06 SER 258

ASN 37 0.26 GLN 272 -0.06 THR 96

LYS 278 0.22 PHE 273 -0.07 THR 96

ASN 37 0.36 LEU 274 -0.07 THR 96

ASP 36 0.43 CYS 275 -0.08 LYS 293

ASP 36 0.40 ASP 276 -0.13 ASN 289

ASP 36 0.30 VAL 277 -0.11 THR 96

ASN 37 0.25 LYS 278 -0.17 PHE 285

ASN 37 0.18 ASP 279 -0.14 THR 96

ASN 37 0.15 PRO 280 -0.16 THR 96

ASN 37 0.13 ALA 281 -0.18 THR 96

ASN 37 0.20 LEU 282 -0.18 THR 96

ASP 36 0.24 CYS 283 -0.20 THR 96

ASP 36 0.32 ASP 284 -0.16 THR 96

ASP 36 0.38 PHE 285 -0.17 LYS 278

ASP 36 0.49 ARG 286 -0.16 LYS 278

ASP 36 0.59 THR 287 -0.12 LYS 278

ASP 36 0.74 ASN 288 -0.12 LYS 278

ASP 36 0.75 ASN 289 -0.13 ASP 276

ASP 36 0.88 ARG 290 -0.09 ASP 276

ASN 37 0.78 HIS 291 -0.09 CYS 292

ASP 36 0.71 CYS 292 -0.09 HIS 291

ASP 36 0.91 LYS 293 -0.09 ASP 276

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.

Should you encounter any unexpected behaviour, please let us know. elNémo has been relocated. **Some cleaning from time to time** Sorry for the inconvenience.

*** HYDROLASE 21-FEB-23 8CMV ***

CA distance fluctuations for 2606131810021463505

--- normal mode 9 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* HYDROLASE 21-FEB-23 8CMV *