Should you encounter any unexpected behaviour,
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elNémo has been relocated.
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* nompcdar29 *

CA strain for 2607010241001575878

--- normal mode 92 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
MET 1 SER 2 -0.0002

SER 2 GLN 3 -0.0001

GLN 3 PRO 4 0.0002

PRO 4 ARG 5 -0.0001

ARG 5 GLY 6 -0.0005

GLY 6 GLY 7 0.0001

GLY 7 ARG 8 0.0000

ARG 8 GLY 9 0.0001

GLY 9 GLY 10 -0.0001

GLY 10 GLY 11 0.0001

GLY 11 ARG 12 -0.0004

ARG 12 GLY 13 -0.0001

GLY 13 GLY 14 0.0002

GLY 14 GLY 15 0.0002

GLY 15 VAL 16 0.0022

VAL 16 GLY 17 0.0002

GLY 17 ARG 18 -0.0001

ARG 18 LYS 19 -0.0001

LYS 19 THR 20 0.0003

THR 20 PRO 21 -0.0004

PRO 21 SER 22 0.0003

SER 22 SER 23 -0.0004

SER 23 LEU 24 0.0000

LEU 24 THR 25 0.0003

THR 25 GLY 26 -0.0001

GLY 26 PRO 27 -0.0002

PRO 27 PRO 28 0.0005

PRO 28 ASP 29 -0.0003

ASP 29 GLU 30 0.0005

GLU 30 SER 31 0.0303

SER 31 ALA 32 -0.0001

ALA 32 THR 33 0.0000

THR 33 PRO 34 -0.0001

PRO 34 SER 35 0.0001

SER 35 GLU 36 0.0001

GLU 36 ARG 37 -0.0001

ARG 37 ALA 38 -0.0005

ALA 38 THR 39 -0.0003

THR 39 PRO 40 0.0001

PRO 40 ALA 41 -0.0002

ALA 41 SER 42 -0.0000

SER 42 LYS 43 -0.0001

LYS 43 ALA 44 0.0003

ALA 44 ASP 45 0.0001

ASP 45 SER 46 0.1052

SER 46 ASP 47 0.0000

ASP 47 PRO 48 0.0002

PRO 48 LYS 49 -0.0003

LYS 49 ASP 50 -0.0001

ASP 50 ASP 51 -0.0002

ASP 51 SER 52 0.0004

SER 52 SER 53 -0.0000

SER 53 SER 54 0.0001

SER 54 ASN 55 0.0001

ASN 55 GLY 56 0.0000

GLY 56 ASP 57 -0.0001

ASP 57 LYS 58 0.0001

LYS 58 LYS 59 0.0002

LYS 59 ASP 60 0.0002

ASP 60 MET 61 0.1591

MET 61 ASP 62 0.0004

ASP 62 LEU 63 -0.0001

LEU 63 PHE 64 -0.0002

PHE 64 PRO 65 0.0002

PRO 65 ALA 66 -0.0002

ALA 66 PRO 67 0.0002

PRO 67 LYS 68 -0.0001

LYS 68 PRO 69 0.0003

PRO 69 PRO 70 0.0000

PRO 70 SER 71 -0.0001

SER 71 ALA 72 0.0000

ALA 72 GLY 73 0.0000

GLY 73 ALA 74 -0.0000

ALA 74 SER 75 -0.0000

SER 75 ILE 76 0.1437

ILE 76 ARG 77 0.0002

ARG 77 ASP 78 0.0001

ASP 78 THR 79 0.0001

THR 79 ALA 80 -0.0002

ALA 80 ASN 81 0.0002

ASN 81 LYS 82 0.0002

LYS 82 VAL 83 0.0002

VAL 83 LEU 84 0.0002

LEU 84 GLY 85 -0.0001

GLY 85 LEU 86 0.0002

LEU 86 ALA 87 -0.0002

ALA 87 MET 88 -0.0002

MET 88 LYS 89 -0.0001

LYS 89 SER 90 0.0001

SER 90 GLU 91 0.0395

GLU 91 TRP 92 -0.0003

TRP 92 THR 93 0.0003

THR 93 PRO 94 0.0002

PRO 94 ILE 95 0.0001

ILE 95 GLU 96 0.0004

GLU 96 ALA 97 0.0003

ALA 97 GLU 98 0.0002

GLU 98 LEU 99 0.0002

LEU 99 LYS 100 -0.0001

LYS 100 LYS 101 -0.0001

LYS 101 LEU 102 0.0002

LEU 102 GLU 103 -0.0001

GLU 103 LYS 104 0.0001

LYS 104 TYR 105 -0.0003

TYR 105 VAL 106 0.0210

VAL 106 ALA 107 -0.0004

ALA 107 ASN 108 -0.0002

ASN 108 VAL 109 -0.0000

VAL 109 GLY 110 0.0001

GLY 110 GLU 111 0.0003

GLU 111 ASP 112 0.0001

ASP 112 GLY 113 -0.0004

GLY 113 ASN 114 -0.0003

ASN 114 HIS 115 -0.0003

HIS 115 ILE 116 -0.0004

ILE 116 PRO 117 -0.0004

PRO 117 LEU 118 -0.0002

LEU 118 ALA 119 -0.0001

ALA 119 GLY 120 0.0001

GLY 120 VAL 121 0.1176

VAL 121 HIS 122 0.0000

HIS 122 ASP 123 0.0002

ASP 123 MET 124 0.0001

MET 124 ASN 125 -0.0004

ASN 125 LEU 126 -0.0001

LEU 126 MET 127 0.0001

MET 127 GLU 128 -0.0004

GLU 128 ASP 129 0.0002

ASP 129 LYS 130 0.0000

LYS 130 ARG 131 0.0004

ARG 131 PHE 132 0.0003

PHE 132 VAL 133 0.0001

VAL 133 TYR 134 0.0004

TYR 134 ASN 135 -0.0001

ASN 135 LEU 136 -0.0248

LEU 136 MET 137 -0.0001

MET 137 VAL 138 -0.0002

VAL 138 VAL 139 0.0001

VAL 139 SER 140 -0.0004

SER 140 LYS 141 0.0004

LYS 141 ASN 142 -0.0001

ASN 142 HIS 143 0.0002

HIS 143 ASN 144 -0.0004

ASN 144 ASN 145 -0.0002

ASN 145 LYS 146 -0.0001

LYS 146 PRO 147 -0.0002

PRO 147 ILE 148 0.0000

ILE 148 GLN 149 0.0001

GLN 149 GLU 150 0.0000

GLU 150 PHE 151 -0.0626

PHE 151 VAL 152 -0.0001

VAL 152 LEU 153 0.0004

LEU 153 VAL 154 -0.0000

VAL 154 SER 155 -0.0001

SER 155 PRO 156 0.0001

PRO 156 ALA 157 0.0002

ALA 157 PRO 158 -0.0000

PRO 158 VAL 159 -0.0001

VAL 159 ASP 160 -0.0000

ASP 160 THR 161 0.0001

THR 161 ALA 162 0.0000

ALA 162 ALA 163 0.0002

ALA 163 LYS 164 0.0003

LYS 164 LEU 165 -0.0000

LEU 165 SER 166 -0.1168

SER 166 ASN 167 0.0001

ASN 167 ILE 168 0.0001

ILE 168 TYR 169 -0.0003

TYR 169 ILE 170 -0.0002

ILE 170 VAL 171 0.0001

VAL 171 LEU 172 0.0000

LEU 172 SER 173 0.0000

SER 173 THR 174 -0.0000

THR 174 LYS 175 -0.0000

LYS 175 GLU 176 0.0002

GLU 176 LYS 177 -0.0005

LYS 177 GLU 178 0.0001

GLU 178 ARG 179 -0.0003

ARG 179 ALA 180 0.0002

ALA 180 LYS 181 -0.1390

LYS 181 ASP 182 0.0001

ASP 182 LEU 183 -0.0002

LEU 183 VAL 184 0.0002

VAL 184 ALA 185 0.0000

ALA 185 ALA 186 0.0001

ALA 186 GLY 187 -0.0000

GLY 187 LYS 188 -0.0001

LYS 188 GLN 189 -0.0003

GLN 189 CYS 190 -0.0002

CYS 190 GLU 191 -0.0001

GLU 191 ALA 192 0.0001

ALA 192 MET 193 0.0000

MET 193 ALA 194 0.0000

ALA 194 THR 195 -0.0000

THR 195 GLU 196 -0.0779

GLU 196 LEU 197 0.0002

LEU 197 LEU 198 -0.0004

LEU 198 ALA 199 -0.0002

ALA 199 LEU 200 -0.0000

LEU 200 ALA 201 -0.0001

ALA 201 ALA 202 0.0000

ALA 202 GLY 203 -0.0001

GLY 203 SER 204 0.0000

SER 204 ASP 205 0.0001

ASP 205 SER 206 -0.0001

SER 206 ALA 207 -0.0001

ALA 207 GLY 208 0.0001

GLY 208 LYS 209 -0.0002

LYS 209 ILE 210 0.0000

ILE 210 LEU 211 -0.1047

LEU 211 GLN 212 -0.0000

GLN 212 ALA 213 -0.0002

ALA 213 THR 214 0.0001

THR 214 ASP 215 -0.0000

ASP 215 LYS 216 0.0002

LYS 216 ARG 217 -0.0001

ARG 217 ASN 218 0.0001

ASN 218 VAL 219 0.0003

VAL 219 GLU 220 -0.0003

GLU 220 PHE 221 -0.0001

PHE 221 LEU 222 -0.0001

LEU 222 ASP 223 0.0002

ASP 223 VAL 224 -0.0001

VAL 224 LEU 225 0.0001

LEU 225 ILE 226 0.2285

ILE 226 GLU 227 0.0000

GLU 227 ASN 228 0.0001

ASN 228 GLU 229 0.0002

GLU 229 GLN 230 -0.0003

GLN 230 LYS 231 0.0000

LYS 231 GLU 232 -0.0001

GLU 232 VAL 233 0.0002

VAL 233 ILE 234 0.0000

ILE 234 ALA 235 -0.0002

ALA 235 HIS 236 -0.0002

HIS 236 THR 237 -0.0001

THR 237 VAL 238 -0.0001

VAL 238 VAL 239 0.0003

VAL 239 GLN 240 -0.0002

GLN 240 ARG 241 0.0846

ARG 241 TYR 242 0.0000

TYR 242 LEU 243 0.0002

LEU 243 GLN 244 -0.0004

GLN 244 GLU 245 0.0001

GLU 245 LEU 246 -0.0003

LEU 246 TRP 247 0.0002

TRP 247 HIS 248 0.0003

HIS 248 GLY 249 -0.0003

GLY 249 SER 250 -0.0001

SER 250 LEU 251 -0.0004

LEU 251 THR 252 0.0000

THR 252 TRP 253 -0.0000

TRP 253 ALA 254 0.0002

ALA 254 SER 255 0.0004

SER 255 TRP 256 0.0587

TRP 256 LYS 257 -0.0002

LYS 257 ILE 258 0.0001

ILE 258 LEU 259 -0.0002

LEU 259 LEU 260 0.0003

LEU 260 LEU 261 -0.0002

LEU 261 LEU 262 -0.0002

LEU 262 VAL 263 0.0001

VAL 263 ALA 264 -0.0002

ALA 264 PHE 265 -0.0000

PHE 265 ILE 266 0.0001

ILE 266 VAL 267 -0.0001

VAL 267 CYS 268 0.0001

CYS 268 PRO 269 -0.0000

PRO 269 PRO 270 -0.0002

PRO 270 VAL 271 -0.0699

VAL 271 TRP 272 0.0002

TRP 272 ILE 273 0.0002

ILE 273 GLY 274 -0.0001

GLY 274 PHE 275 -0.0002

PHE 275 THR 276 0.0004

THR 276 PHE 277 0.0000

PHE 277 PRO 278 0.0000

PRO 278 MET 279 0.0002

MET 279 GLY 280 -0.0000

GLY 280 HIS 281 -0.0001

HIS 281 LYS 282 0.0002

LYS 282 PHE 283 -0.0002

PHE 283 ASN 284 0.0000

ASN 284 LYS 285 -0.0004

LYS 285 VAL 286 0.0070

VAL 286 PRO 287 -0.0002

PRO 287 ILE 288 -0.0000

ILE 288 ILE 289 0.0001

ILE 289 LYS 290 0.0000

LYS 290 PHE 291 -0.0003

PHE 291 MET 292 -0.0002

MET 292 SER 293 0.0002

SER 293 TYR 294 0.0001

TYR 294 LEU 295 -0.0004

LEU 295 THR 296 0.0001

THR 296 SER 297 0.0002

SER 297 HIS 298 -0.0001

HIS 298 ILE 299 -0.0003

ILE 299 TYR 300 -0.0002

TYR 300 LEU 301 0.1343

LEU 301 MET 302 -0.0003

MET 302 ILE 303 -0.0003

ILE 303 HIS 304 -0.0001

HIS 304 LEU 305 -0.0001

LEU 305 SER 306 0.0003

SER 306 ILE 307 0.0001

ILE 307 VAL 308 -0.0000

VAL 308 GLY 309 -0.0003

GLY 309 ILE 310 0.0002

ILE 310 THR 311 0.0001

THR 311 PRO 312 0.0001

PRO 312 ILE 313 0.0002

ILE 313 TYR 314 0.0000

TYR 314 PRO 315 -0.0002

PRO 315 VAL 316 0.0423

VAL 316 LEU 317 0.0001

LEU 317 ARG 318 -0.0003

ARG 318 LEU 319 0.0002

LEU 319 SER 320 0.0000

SER 320 LEU 321 -0.0001

LEU 321 VAL 322 -0.0002

VAL 322 PRO 323 -0.0003

PRO 323 TYR 324 0.0004

TYR 324 TRP 325 -0.0001

TRP 325 TYR 326 0.0005

TYR 326 GLU 327 0.0000

GLU 327 VAL 328 -0.0003

VAL 328 GLY 329 0.0002

GLY 329 LEU 330 0.0004

LEU 330 LEU 331 -0.0446

LEU 331 ILE 332 -0.0001

ILE 332 TRP 333 0.0001

TRP 333 LEU 334 0.0000

LEU 334 SER 335 0.0002

SER 335 GLY 336 -0.0001

GLY 336 LEU 337 -0.0003

LEU 337 LEU 338 0.0001

LEU 338 LEU 339 0.0000

LEU 339 PHE 340 0.0002

PHE 340 GLU 341 0.0000

GLU 341 LEU 342 0.0001

LEU 342 THR 343 -0.0002

THR 343 ASN 344 0.0004

ASN 344 PRO 345 0.0001

PRO 345 SER 346 0.1180

SER 346 ASP 347 0.0001

ASP 347 LYS 348 0.0002

LYS 348 SER 349 0.0001

SER 349 GLY 350 0.0002

GLY 350 LEU 351 -0.0003

LEU 351 GLY 352 -0.0002

GLY 352 SER 353 -0.0001

SER 353 ILE 354 0.0001

ILE 354 LYS 355 0.0002

LYS 355 VAL 356 0.0003

VAL 356 LEU 357 -0.0001

LEU 357 VAL 358 0.0004

VAL 358 LEU 359 0.0001

LEU 359 LEU 360 -0.0001

LEU 360 LEU 361 0.0198

LEU 361 GLY 362 -0.0000

GLY 362 MET 363 0.0001

MET 363 ALA 364 0.0002

ALA 364 GLY 365 0.0003

GLY 365 VAL 366 0.0001

VAL 366 GLY 367 -0.0001

GLY 367 VAL 368 0.0001

VAL 368 HIS 369 0.0001

HIS 369 VAL 370 0.0005

VAL 370 SER 371 -0.0000

SER 371 ALA 372 0.0002

ALA 372 PHE 373 0.0000

PHE 373 LEU 374 -0.0004

LEU 374 PHE 375 0.0001

PHE 375 VAL 376 0.0478

VAL 376 SER 377 0.0000

SER 377 LYS 378 -0.0004

LYS 378 GLU 379 0.0000

GLU 379 TYR 380 0.0002

TYR 380 TRP 381 0.0003

TRP 381 PRO 382 0.0001

PRO 382 THR 383 0.0000

THR 383 LEU 384 -0.0000

LEU 384 VAL 385 -0.0003

VAL 385 TYR 386 0.0001

TYR 386 CYS 387 0.0001

CYS 387 ARG 388 0.0002

ARG 388 ASN 389 0.0003

ASN 389 GLN 390 0.0000

GLN 390 CYS 391 0.0181

CYS 391 PHE 392 -0.0002

PHE 392 ALA 393 0.0003

ALA 393 LEU 394 0.0000

LEU 394 ALA 395 -0.0002

ALA 395 PHE 396 -0.0004

PHE 396 LEU 397 -0.0000

LEU 397 LEU 398 0.0002

LEU 398 ALA 399 -0.0000

ALA 399 CYS 400 0.0001

CYS 400 VAL 401 0.0002

VAL 401 GLN 402 -0.0001

GLN 402 ILE 403 -0.0000

ILE 403 LEU 404 -0.0000

LEU 404 ASP 405 -0.0001

ASP 405 PHE 406 -0.0649

PHE 406 LEU 407 0.0002

LEU 407 SER 408 -0.0004

SER 408 PHE 409 -0.0003

PHE 409 HIS 410 0.0000

HIS 410 HIS 411 0.0001

HIS 411 LEU 412 0.0002

LEU 412 PHE 413 0.0000

PHE 413 GLY 414 0.0001

GLY 414 PRO 415 0.0000

PRO 415 TRP 416 0.0002

TRP 416 ALA 417 -0.0002

ALA 417 ILE 418 -0.0003

ILE 418 ILE 419 -0.0003

ILE 419 ILE 420 -0.0003

ILE 420 GLY 421 -0.1638

GLY 421 ASP 422 0.0003

ASP 422 LEU 423 -0.0003

LEU 423 LEU 424 -0.0001

LEU 424 LYS 425 -0.0001

LYS 425 ASP 426 -0.0004

ASP 426 LEU 427 0.0000

LEU 427 ALA 428 -0.0003

ALA 428 ARG 429 -0.0002

ARG 429 PHE 430 -0.0001

PHE 430 LEU 431 0.0001

LEU 431 ALA 432 0.0004

ALA 432 VAL 433 0.0002

VAL 433 LEU 434 -0.0000

LEU 434 ALA 435 0.0002

ALA 435 ILE 436 0.2487

ILE 436 PHE 437 -0.0002

PHE 437 VAL 438 0.0001

VAL 438 PHE 439 0.0002

PHE 439 GLY 440 0.0001

GLY 440 PHE 441 -0.0000

PHE 441 SER 442 -0.0000

SER 442 MET 443 0.0000

MET 443 HIS 444 0.0002

HIS 444 ILE 445 -0.0000

ILE 445 VAL 446 0.0001

VAL 446 ALA 447 -0.0002

ALA 447 LEU 448 0.0005

LEU 448 ASN 449 0.0001

ASN 449 GLN 450 0.0002

GLN 450 SER 451 0.0604

SER 451 PHE 452 -0.0001

PHE 452 ALA 453 0.0002

ALA 453 ASN 454 0.0000

ASN 454 PHE 455 0.0002

PHE 455 SER 456 -0.0004

SER 456 PRO 457 -0.0001

PRO 457 GLU 458 0.0003

GLU 458 ASP 459 -0.0003

ASP 459 LEU 460 -0.0000

LEU 460 ARG 461 0.0000

ARG 461 SER 462 0.0001

SER 462 PHE 463 -0.0001

PHE 463 GLU 464 -0.0003

GLU 464 LYS 465 -0.0005

LYS 465 LYS 466 0.1741

LYS 466 ASN 467 -0.0003

ASN 467 ARG 468 -0.0001

ARG 468 ASN 469 0.0003

ASN 469 ARG 470 -0.0003

ARG 470 GLY 471 -0.0002

GLY 471 TYR 472 0.0001

TYR 472 PHE 473 -0.0005

PHE 473 SER 474 0.0001

SER 474 ASP 475 0.0002

ASP 475 VAL 476 0.0000

VAL 476 ARG 477 -0.0001

ARG 477 MET 478 -0.0004

MET 478 HIS 479 -0.0000

HIS 479 PRO 480 0.0001

PRO 480 ILE 481 0.1396

ILE 481 ASN 482 0.0003

ASN 482 SER 483 -0.0001

SER 483 PHE 484 0.0002

PHE 484 GLU 485 -0.0001

GLU 485 LEU 486 0.0000

LEU 486 LEU 487 -0.0001

LEU 487 PHE 488 0.0001

PHE 488 PHE 489 0.0000

PHE 489 ALA 490 -0.0001

ALA 490 VAL 491 0.0001

VAL 491 PHE 492 -0.0000

PHE 492 GLY 493 -0.0002

GLY 493 GLN 494 -0.0002

GLN 494 THR 495 -0.0001

THR 495 THR 496 0.0227

THR 496 THR 497 0.0002

THR 497 GLU 498 0.0001

GLU 498 GLN 499 0.0000

GLN 499 THR 500 -0.0002

THR 500 GLN 501 -0.0003

GLN 501 VAL 502 -0.0001

VAL 502 ASP 503 -0.0004

ASP 503 LYS 504 -0.0005

LYS 504 ILE 505 0.0002

ILE 505 LYS 506 0.0004

LYS 506 ASN 507 0.0000

ASN 507 VAL 508 -0.0001

VAL 508 ALA 509 -0.0004

ALA 509 THR 510 0.0004

THR 510 PRO 511 -0.0736

PRO 511 THR 512 -0.0002

THR 512 GLN 513 0.0000

GLN 513 PRO 514 0.0002

PRO 514 TYR 515 -0.0002

TYR 515 TRP 516 0.0001

TRP 516 VAL 517 0.0002

VAL 517 GLU 518 -0.0003

GLU 518 TYR 519 0.0002

TYR 519 LEU 520 -0.0000

LEU 520 PHE 521 0.0003

PHE 521 LYS 522 0.0002

LYS 522 ILE 523 0.0001

ILE 523 VAL 524 -0.0001

VAL 524 PHE 525 -0.0001

PHE 525 GLY 526 -0.0886

GLY 526 ILE 527 -0.0001

ILE 527 TYR 528 -0.0004

TYR 528 MET 529 -0.0004

MET 529 LEU 530 -0.0000

LEU 530 VAL 531 0.0002

VAL 531 SER 532 -0.0003

SER 532 VAL 533 0.0002

VAL 533 VAL 534 0.0001

VAL 534 VAL 535 0.0000

VAL 535 LEU 536 0.0003

LEU 536 ILE 537 -0.0004

ILE 537 ASN 538 0.0002

ASN 538 LEU 539 0.0001

LEU 539 LEU 540 -0.0001

LEU 540 ILE 541 0.0235

ILE 541 ALA 542 0.0004

ALA 542 MET 543 0.0000

MET 543 MET 544 -0.0000

MET 544 SER 545 -0.0000

SER 545 ASP 546 0.0002

ASP 546 THR 547 -0.0001

THR 547 TYR 548 0.0000

TYR 548 GLN 549 0.0003

GLN 549 ARG 550 -0.0000

ARG 550 ILE 551 0.0001

ILE 551 GLN 552 0.0004

GLN 552 ALA 553 -0.0005

ALA 553 GLN 554 -0.0000

GLN 554 SER 555 0.0001

SER 555 ASP 556 0.1550

ASP 556 ILE 557 -0.0003

ILE 557 GLU 558 -0.0003

GLU 558 TRP 559 0.0001

TRP 559 LYS 560 -0.0003

LYS 560 PHE 561 0.0001

PHE 561 GLY 562 0.0002

GLY 562 LEU 563 0.0000

LEU 563 SER 564 -0.0003

SER 564 LYS 565 0.0002

LYS 565 LEU 566 0.0000

LEU 566 ILE 567 0.0002

ILE 567 ARG 568 -0.0003

ARG 568 ASN 569 0.0002

ASN 569 MET 570 -0.0001

MET 570 HIS 571 0.1629

HIS 571 ARG 572 -0.0002

ARG 572 THR 573 0.0002

THR 573 THR 574 0.0000

THR 574 THR 575 -0.0003

THR 575 ALA 576 0.0005

ALA 576 PRO 577 -0.0005

PRO 577 SER 578 0.0000

SER 578 PRO 579 0.0004

PRO 579 LEU 580 0.0003

LEU 580 ASN 581 0.0003

ASN 581 LEU 582 0.0001

LEU 582 VAL 583 0.0003

VAL 583 THR 584 -0.0000

THR 584 THR 585 -0.0004

THR 585 TRP 586 -0.6065

TRP 586 PHE 587 -0.0003

PHE 587 MET 588 -0.0000

MET 588 TRP 589 0.0003

TRP 589 ILE 590 -0.0002

ILE 590 VAL 591 0.0001

VAL 591 GLU 592 0.0002

GLU 592 LYS 593 0.0000

LYS 593 VAL 594 -0.0004

VAL 594 LYS 595 -0.0000

LYS 595 ALA 596 0.0001

ALA 596 ARG 597 0.0001

ARG 597 MET 598 0.0003

MET 598 LYS 599 -0.0001

LYS 599 LYS 600 -0.0000

LYS 600 LYS 601 -0.0031

LYS 601 LYS 602 -0.0001

LYS 602 ARG 603 -0.0000

ARG 603 PRO 604 0.0000

PRO 604 SER 605 -0.0000

SER 605 LEU 606 -0.0002

LEU 606 VAL 607 -0.0001

VAL 607 GLN 608 0.0002

GLN 608 MET 609 0.0000

MET 609 MET 610 -0.0003

MET 610 GLY 611 -0.0001

GLY 611 ILE 612 0.0002

ILE 612 ARG 613 -0.0002

ARG 613 GLN 614 0.0001

GLN 614 ALA 615 0.0000

ALA 615 SER 616 0.1226

SER 616 PRO 617 0.0000

PRO 617 ARG 618 0.0001

ARG 618 THR 619 -0.0001

THR 619 LYS 620 -0.0002

LYS 620 ALA 621 -0.0000

ALA 621 GLY 622 -0.0001

GLY 622 ALA 623 -0.0002

ALA 623 LYS 624 -0.0002

LYS 624 TRP 625 0.0003

TRP 625 LEU 626 0.0000

LEU 626 SER 627 0.0002

SER 627 LYS 628 0.0002

LYS 628 ILE 629 0.0000

ILE 629 LYS 630 -0.0002

LYS 630 LYS 631 -0.0868

LYS 631 ASP 632 -0.0002

ASP 632 SER 633 -0.0002

SER 633 VAL 634 0.0003

VAL 634 ALA 635 0.0003

ALA 635 LEU 636 -0.0002

LEU 636 SER 637 0.0001

SER 637 GLN 638 -0.0001

GLN 638 VAL 639 -0.0001

VAL 639 HIS 640 0.0003

HIS 640 LEU 641 -0.0003

LEU 641 SER 642 0.0001

SER 642 PRO 643 0.0002

PRO 643 LEU 644 0.0001

LEU 644 GLY 645 -0.0001

GLY 645 SER 646 0.1457

SER 646 GLN 647 -0.0001

GLN 647 ALA 648 -0.0000

ALA 648 SER 649 -0.0003

SER 649 PHE 650 -0.0004

PHE 650 SER 651 -0.0001

SER 651 GLN 652 -0.0003

GLN 652 ALA 653 -0.0000

ALA 653 ASN 654 -0.0001

ASN 654 GLN 655 0.0001

GLN 655 ASN 656 -0.0002

ASN 656 ARG 657 -0.0000

ARG 657 ILE 658 0.0002

ILE 658 GLU 659 -0.0001

GLU 659 ASN 660 -0.0000

ASN 660 VAL 661 0.0320

VAL 661 ALA 662 0.0001

ALA 662 ASP 663 0.0000

ASP 663 TRP 664 0.0002

TRP 664 GLU 665 -0.0003

GLU 665 ALA 666 -0.0000

ALA 666 ILE 667 0.0001

ILE 667 ALA 668 0.0000

ALA 668 LYS 669 -0.0003

LYS 669 LYS 670 0.0001

LYS 670 TYR 671 0.0000

TYR 671 ARG 672 0.0002

ARG 672 ALA 673 -0.0002

ALA 673 LEU 674 -0.0002

LEU 674 VAL 675 0.0002

VAL 675 GLY 676 -0.1505

GLY 676 ASP 677 0.0001

ASP 677 GLU 678 0.0001

GLU 678 GLU 679 -0.0003

GLU 679 GLY 680 -0.0001

GLY 680 GLY 681 -0.0002

GLY 681 SER 682 -0.0000

SER 682 LEU 683 0.0002

LEU 683 LYS 684 -0.0001

LYS 684 ASP 685 -0.0000

ASP 685 SER 686 -0.0002

SER 686 ASP 687 -0.0000

ASP 687 ALA 688 -0.0002

ALA 688 GLU 689 -0.0001

GLU 689 SER 690 -0.0001

SER 690 GLY 691 0.1251

GLY 691 SER 692 0.0002

SER 692 GLN 693 -0.0001

GLN 693 GLU 694 -0.0001

GLU 694 GLY 695 -0.0003

GLY 695 SER 696 0.0001

SER 696 GLY 697 0.0000

GLY 697 GLY 698 -0.0002

GLY 698 GLN 699 0.0001

GLN 699 GLN 700 -0.0003

GLN 700 PRO 701 0.0001

PRO 701 PRO 702 0.0002

PRO 702 ALA 703 0.0001

ALA 703 GLN 704 -0.0001

GLN 704 VAL 705 -0.0001

VAL 705 GLY 706 0.1485

GLY 706 ARG 707 -0.0001

ARG 707 ARG 708 0.0001

ARG 708 ALA 709 -0.0004

ALA 709 ILE 710 0.0002

ILE 710 LYS 711 -0.0000

LYS 711 ALA 712 -0.0003

ALA 712 THR 713 -0.0001

THR 713 LEU 714 0.0003

LEU 714 ALA 715 0.0001

ALA 715 ASP 716 -0.0000

ASP 716 THR 717 -0.0002

THR 717 THR 718 -0.0003

THR 718 LYS 719 0.0000

LYS 719 MET 1 0.1603

MET 1 SER 2 -0.0002

SER 2 GLN 3 -0.0000

GLN 3 PRO 4 -0.0001

PRO 4 ARG 5 -0.0001

ARG 5 GLY 6 -0.0004

GLY 6 GLY 7 0.0005

GLY 7 ARG 8 -0.0003

ARG 8 GLY 9 0.0000

GLY 9 GLY 10 -0.0001

GLY 10 GLY 11 0.0007

GLY 11 ARG 12 -0.0004

ARG 12 GLY 13 0.0000

GLY 13 GLY 14 0.0000

GLY 14 GLY 15 -0.0001

GLY 15 VAL 16 -0.0076

VAL 16 GLY 17 0.0000

GLY 17 ARG 18 0.0003

ARG 18 LYS 19 -0.0000

LYS 19 THR 20 -0.0002

THR 20 PRO 21 0.0005

PRO 21 SER 22 -0.0005

SER 22 SER 23 0.0002

SER 23 LEU 24 -0.0001

LEU 24 THR 25 0.0002

THR 25 GLY 26 0.0003

GLY 26 PRO 27 -0.0001

PRO 27 PRO 28 -0.0004

PRO 28 ASP 29 0.0004

ASP 29 GLU 30 -0.0003

GLU 30 SER 31 0.0366

SER 31 ALA 32 -0.0002

ALA 32 THR 33 -0.0001

THR 33 PRO 34 0.0005

PRO 34 SER 35 -0.0003

SER 35 GLU 36 -0.0001

GLU 36 ARG 37 0.0005

ARG 37 ALA 38 -0.0004

ALA 38 THR 39 0.0000

THR 39 PRO 40 0.0002

PRO 40 ALA 41 0.0002

ALA 41 SER 42 -0.0001

SER 42 LYS 43 -0.0000

LYS 43 ALA 44 0.0001

ALA 44 ASP 45 -0.0004

ASP 45 SER 46 -0.0004

SER 46 ASP 47 0.0004

ASP 47 PRO 48 -0.0005

PRO 48 LYS 49 0.0004

LYS 49 ASP 50 -0.0003

ASP 50 ASP 51 -0.0003

ASP 51 SER 52 -0.0001

SER 52 SER 53 0.0001

SER 53 SER 54 -0.0002

SER 54 ASN 55 -0.0002

ASN 55 GLY 56 -0.0003

GLY 56 ASP 57 -0.0004

ASP 57 LYS 58 0.0001

LYS 58 LYS 59 0.0000

LYS 59 ASP 60 0.0004

ASP 60 MET 61 -0.0198

MET 61 ASP 62 -0.0001

ASP 62 LEU 63 -0.0001

LEU 63 PHE 64 0.0002

PHE 64 PRO 65 -0.0001

PRO 65 ALA 66 -0.0002

ALA 66 PRO 67 -0.0000

PRO 67 LYS 68 -0.0003

LYS 68 PRO 69 -0.0000

PRO 69 PRO 70 0.0000

PRO 70 SER 71 0.0002

SER 71 ALA 72 -0.0001

ALA 72 GLY 73 0.0001

GLY 73 ALA 74 0.0001

ALA 74 SER 75 0.0000

SER 75 ILE 76 -0.0977

ILE 76 ARG 77 0.0000

ARG 77 ASP 78 0.0000

ASP 78 THR 79 0.0001

THR 79 ALA 80 0.0001

ALA 80 ASN 81 -0.0002

ASN 81 LYS 82 -0.0001

LYS 82 VAL 83 0.0002

VAL 83 LEU 84 0.0001

LEU 84 GLY 85 -0.0003

GLY 85 LEU 86 0.0002

LEU 86 ALA 87 0.0002

ALA 87 MET 88 0.0001

MET 88 LYS 89 -0.0000

LYS 89 SER 90 0.0003

SER 90 GLU 91 0.0026

GLU 91 TRP 92 0.0003

TRP 92 THR 93 -0.0003

THR 93 PRO 94 0.0002

PRO 94 ILE 95 -0.0002

ILE 95 GLU 96 0.0001

GLU 96 ALA 97 0.0002

ALA 97 GLU 98 0.0003

GLU 98 LEU 99 -0.0000

LEU 99 LYS 100 0.0002

LYS 100 LYS 101 0.0003

LYS 101 LEU 102 -0.0000

LEU 102 GLU 103 -0.0001

GLU 103 LYS 104 0.0001

LYS 104 TYR 105 -0.0001

TYR 105 VAL 106 -0.0365

VAL 106 ALA 107 0.0000

ALA 107 ASN 108 0.0001

ASN 108 VAL 109 0.0000

VAL 109 GLY 110 0.0001

GLY 110 GLU 111 -0.0001

GLU 111 ASP 112 0.0004

ASP 112 GLY 113 0.0000

GLY 113 ASN 114 0.0002

ASN 114 HIS 115 -0.0000

HIS 115 ILE 116 -0.0003

ILE 116 PRO 117 0.0000

PRO 117 LEU 118 -0.0003

LEU 118 ALA 119 -0.0000

ALA 119 GLY 120 -0.0003

GLY 120 VAL 121 0.0264

VAL 121 HIS 122 -0.0001

HIS 122 ASP 123 -0.0003

ASP 123 MET 124 -0.0001

MET 124 ASN 125 -0.0004

ASN 125 LEU 126 -0.0001

LEU 126 MET 127 -0.0001

MET 127 GLU 128 0.0001

GLU 128 ASP 129 0.0004

ASP 129 LYS 130 0.0001

LYS 130 ARG 131 0.0002

ARG 131 PHE 132 -0.0001

PHE 132 VAL 133 -0.0002

VAL 133 TYR 134 -0.0002

TYR 134 ASN 135 -0.0001

ASN 135 LEU 136 0.0118

LEU 136 MET 137 0.0003

MET 137 VAL 138 0.0003

VAL 138 VAL 139 0.0000

VAL 139 SER 140 -0.0002

SER 140 LYS 141 0.0001

LYS 141 ASN 142 -0.0002

ASN 142 HIS 143 0.0002

HIS 143 ASN 144 -0.0002

ASN 144 ASN 145 -0.0001

ASN 145 LYS 146 -0.0003

LYS 146 PRO 147 0.0001

PRO 147 ILE 148 0.0003

ILE 148 GLN 149 -0.0002

GLN 149 GLU 150 -0.0003

GLU 150 PHE 151 -0.0137

PHE 151 VAL 152 -0.0002

VAL 152 LEU 153 -0.0002

LEU 153 VAL 154 -0.0000

VAL 154 SER 155 0.0001

SER 155 PRO 156 0.0002

PRO 156 ALA 157 -0.0003

ALA 157 PRO 158 -0.0001

PRO 158 VAL 159 -0.0000

VAL 159 ASP 160 -0.0002

ASP 160 THR 161 -0.0002

THR 161 ALA 162 0.0000

ALA 162 ALA 163 0.0002

ALA 163 LYS 164 0.0001

LYS 164 LEU 165 -0.0003

LEU 165 SER 166 0.0259

SER 166 ASN 167 -0.0003

ASN 167 ILE 168 0.0004

ILE 168 TYR 169 0.0001

TYR 169 ILE 170 -0.0001

ILE 170 VAL 171 0.0000

VAL 171 LEU 172 0.0000

LEU 172 SER 173 -0.0000

SER 173 THR 174 -0.0000

THR 174 LYS 175 -0.0000

LYS 175 GLU 176 0.0001

GLU 176 LYS 177 -0.0005

LYS 177 GLU 178 0.0000

GLU 178 ARG 179 -0.0002

ARG 179 ALA 180 -0.0003

ALA 180 LYS 181 -0.0152

LYS 181 ASP 182 0.0001

ASP 182 LEU 183 0.0000

LEU 183 VAL 184 0.0003

VAL 184 ALA 185 0.0001

ALA 185 ALA 186 0.0003

ALA 186 GLY 187 -0.0002

GLY 187 LYS 188 0.0002

LYS 188 GLN 189 -0.0001

GLN 189 CYS 190 0.0000

CYS 190 GLU 191 0.0002

GLU 191 ALA 192 0.0003

ALA 192 MET 193 0.0001

MET 193 ALA 194 -0.0003

ALA 194 THR 195 0.0000

THR 195 GLU 196 0.0682

GLU 196 LEU 197 0.0003

LEU 197 LEU 198 -0.0001

LEU 198 ALA 199 0.0003

ALA 199 LEU 200 -0.0001

LEU 200 ALA 201 0.0000

ALA 201 ALA 202 -0.0001

ALA 202 GLY 203 -0.0001

GLY 203 SER 204 0.0002

SER 204 ASP 205 -0.0003

ASP 205 SER 206 -0.0001

SER 206 ALA 207 -0.0001

ALA 207 GLY 208 0.0002

GLY 208 LYS 209 -0.0001

LYS 209 ILE 210 0.0000

ILE 210 LEU 211 -0.0765

LEU 211 GLN 212 -0.0003

GLN 212 ALA 213 -0.0000

ALA 213 THR 214 0.0001

THR 214 ASP 215 -0.0001

ASP 215 LYS 216 -0.0001

LYS 216 ARG 217 0.0003

ARG 217 ASN 218 -0.0001

ASN 218 VAL 219 -0.0002

VAL 219 GLU 220 -0.0001

GLU 220 PHE 221 -0.0001

PHE 221 LEU 222 0.0004

LEU 222 ASP 223 -0.0001

ASP 223 VAL 224 0.0000

VAL 224 LEU 225 -0.0002

LEU 225 ILE 226 -0.0586

ILE 226 GLU 227 0.0002

GLU 227 ASN 228 0.0002

ASN 228 GLU 229 -0.0000

GLU 229 GLN 230 -0.0002

GLN 230 LYS 231 -0.0001

LYS 231 GLU 232 0.0000

GLU 232 VAL 233 -0.0005

VAL 233 ILE 234 -0.0003

ILE 234 ALA 235 -0.0001

ALA 235 HIS 236 -0.0002

HIS 236 THR 237 0.0001

THR 237 VAL 238 -0.0000

VAL 238 VAL 239 0.0002

VAL 239 GLN 240 -0.0000

GLN 240 ARG 241 -0.0447

ARG 241 TYR 242 0.0000

TYR 242 LEU 243 -0.0003

LEU 243 GLN 244 0.0003

GLN 244 GLU 245 0.0005

GLU 245 LEU 246 0.0000

LEU 246 TRP 247 -0.0003

TRP 247 HIS 248 -0.0001

HIS 248 GLY 249 -0.0002

GLY 249 SER 250 -0.0001

SER 250 LEU 251 -0.0002

LEU 251 THR 252 0.0000

THR 252 TRP 253 -0.0002

TRP 253 ALA 254 -0.0001

ALA 254 SER 255 0.0001

SER 255 TRP 256 0.0395

TRP 256 LYS 257 -0.0004

LYS 257 ILE 258 0.0003

ILE 258 LEU 259 0.0002

LEU 259 LEU 260 0.0001

LEU 260 LEU 261 -0.0001

LEU 261 LEU 262 0.0000

LEU 262 VAL 263 0.0001

VAL 263 ALA 264 0.0001

ALA 264 PHE 265 -0.0003

PHE 265 ILE 266 0.0001

ILE 266 VAL 267 0.0005

VAL 267 CYS 268 0.0004

CYS 268 PRO 269 -0.0001

PRO 269 PRO 270 -0.0002

PRO 270 VAL 271 -0.0403

VAL 271 TRP 272 0.0003

TRP 272 ILE 273 0.0001

ILE 273 GLY 274 0.0000

GLY 274 PHE 275 -0.0001

PHE 275 THR 276 -0.0000

THR 276 PHE 277 0.0000

PHE 277 PRO 278 0.0002

PRO 278 MET 279 0.0001

MET 279 GLY 280 0.0002

GLY 280 HIS 281 -0.0001

HIS 281 LYS 282 -0.0001

LYS 282 PHE 283 0.0001

PHE 283 ASN 284 0.0001

ASN 284 LYS 285 -0.0003

LYS 285 VAL 286 0.0186

VAL 286 PRO 287 0.0003

PRO 287 ILE 288 -0.0000

ILE 288 ILE 289 0.0003

ILE 289 LYS 290 0.0001

LYS 290 PHE 291 -0.0000

PHE 291 MET 292 -0.0000

MET 292 SER 293 0.0000

SER 293 TYR 294 0.0000

TYR 294 LEU 295 0.0003

LEU 295 THR 296 0.0003

THR 296 SER 297 -0.0001

SER 297 HIS 298 0.0003

HIS 298 ILE 299 0.0001

ILE 299 TYR 300 -0.0002

TYR 300 LEU 301 0.0752

LEU 301 MET 302 -0.0000

MET 302 ILE 303 0.0003

ILE 303 HIS 304 0.0003

HIS 304 LEU 305 0.0001

LEU 305 SER 306 -0.0005

SER 306 ILE 307 0.0002

ILE 307 VAL 308 0.0000

VAL 308 GLY 309 -0.0003

GLY 309 ILE 310 0.0001

ILE 310 THR 311 -0.0000

THR 311 PRO 312 0.0004

PRO 312 ILE 313 0.0001

ILE 313 TYR 314 -0.0001

TYR 314 PRO 315 0.0001

PRO 315 VAL 316 -0.0092

VAL 316 LEU 317 -0.0001

LEU 317 ARG 318 -0.0001

ARG 318 LEU 319 -0.0001

LEU 319 SER 320 0.0001

SER 320 LEU 321 -0.0003

LEU 321 VAL 322 -0.0004

VAL 322 PRO 323 -0.0001

PRO 323 TYR 324 -0.0001

TYR 324 TRP 325 -0.0002

TRP 325 TYR 326 -0.0002

TYR 326 GLU 327 0.0000

GLU 327 VAL 328 0.0001

VAL 328 GLY 329 -0.0000

GLY 329 LEU 330 -0.0000

LEU 330 LEU 331 -0.0869

LEU 331 ILE 332 -0.0000

ILE 332 TRP 333 0.0002

TRP 333 LEU 334 0.0002

LEU 334 SER 335 -0.0000

SER 335 GLY 336 0.0000

GLY 336 LEU 337 -0.0001

LEU 337 LEU 338 0.0001

LEU 338 LEU 339 -0.0001

LEU 339 PHE 340 0.0002

PHE 340 GLU 341 -0.0003

GLU 341 LEU 342 0.0001

LEU 342 THR 343 0.0001

THR 343 ASN 344 -0.0003

ASN 344 PRO 345 -0.0002

PRO 345 SER 346 -0.0157

SER 346 ASP 347 -0.0000

ASP 347 LYS 348 -0.0003

LYS 348 SER 349 -0.0000

SER 349 GLY 350 -0.0001

GLY 350 LEU 351 -0.0002

LEU 351 GLY 352 0.0004

GLY 352 SER 353 0.0002

SER 353 ILE 354 0.0002

ILE 354 LYS 355 0.0003

LYS 355 VAL 356 -0.0001

VAL 356 LEU 357 0.0000

LEU 357 VAL 358 -0.0002

VAL 358 LEU 359 0.0002

LEU 359 LEU 360 -0.0001

LEU 360 LEU 361 0.0429

LEU 361 GLY 362 0.0001

GLY 362 MET 363 0.0001

MET 363 ALA 364 0.0001

ALA 364 GLY 365 -0.0001

GLY 365 VAL 366 0.0003

VAL 366 GLY 367 0.0001

GLY 367 VAL 368 -0.0002

VAL 368 HIS 369 -0.0002

HIS 369 VAL 370 0.0002

VAL 370 SER 371 -0.0002

SER 371 ALA 372 -0.0003

ALA 372 PHE 373 0.0002

PHE 373 LEU 374 -0.0001

LEU 374 PHE 375 -0.0003

PHE 375 VAL 376 0.0634

VAL 376 SER 377 -0.0001

SER 377 LYS 378 -0.0000

LYS 378 GLU 379 0.0002

GLU 379 TYR 380 -0.0002

TYR 380 TRP 381 0.0003

TRP 381 PRO 382 -0.0005

PRO 382 THR 383 -0.0004

THR 383 LEU 384 -0.0003

LEU 384 VAL 385 0.0000

VAL 385 TYR 386 -0.0001

TYR 386 CYS 387 -0.0001

CYS 387 ARG 388 -0.0000

ARG 388 ASN 389 0.0001

ASN 389 GLN 390 -0.0002

GLN 390 CYS 391 0.0381

CYS 391 PHE 392 0.0001

PHE 392 ALA 393 -0.0001

ALA 393 LEU 394 -0.0003

LEU 394 ALA 395 0.0000

ALA 395 PHE 396 0.0002

PHE 396 LEU 397 -0.0000

LEU 397 LEU 398 0.0000

LEU 398 ALA 399 -0.0001

ALA 399 CYS 400 0.0005

CYS 400 VAL 401 0.0001

VAL 401 GLN 402 -0.0000

GLN 402 ILE 403 -0.0001

ILE 403 LEU 404 -0.0002

LEU 404 ASP 405 0.0003

ASP 405 PHE 406 -0.0491

PHE 406 LEU 407 0.0001

LEU 407 SER 408 0.0004

SER 408 PHE 409 0.0004

PHE 409 HIS 410 -0.0001

HIS 410 HIS 411 -0.0004

HIS 411 LEU 412 -0.0001

LEU 412 PHE 413 0.0001

PHE 413 GLY 414 0.0000

GLY 414 PRO 415 -0.0002

PRO 415 TRP 416 -0.0003

TRP 416 ALA 417 0.0004

ALA 417 ILE 418 0.0002

ILE 418 ILE 419 0.0004

ILE 419 ILE 420 0.0003

ILE 420 GLY 421 0.0064

GLY 421 ASP 422 -0.0002

ASP 422 LEU 423 -0.0000

LEU 423 LEU 424 0.0001

LEU 424 LYS 425 0.0001

LYS 425 ASP 426 -0.0000

ASP 426 LEU 427 0.0002

LEU 427 ALA 428 -0.0004

ALA 428 ARG 429 0.0002

ARG 429 PHE 430 -0.0001

PHE 430 LEU 431 -0.0001

LEU 431 ALA 432 -0.0005

ALA 432 VAL 433 -0.0000

VAL 433 LEU 434 0.0004

LEU 434 ALA 435 0.0001

ALA 435 ILE 436 0.0874

ILE 436 PHE 437 0.0001

PHE 437 VAL 438 -0.0002

VAL 438 PHE 439 -0.0000

PHE 439 GLY 440 0.0002

GLY 440 PHE 441 -0.0002

PHE 441 SER 442 0.0000

SER 442 MET 443 -0.0001

MET 443 HIS 444 0.0001

HIS 444 ILE 445 0.0002

ILE 445 VAL 446 -0.0001

VAL 446 ALA 447 -0.0000

ALA 447 LEU 448 0.0002

LEU 448 ASN 449 0.0001

ASN 449 GLN 450 0.0003

GLN 450 SER 451 0.0086

SER 451 PHE 452 0.0002

PHE 452 ALA 453 0.0000

ALA 453 ASN 454 -0.0003

ASN 454 PHE 455 -0.0001

PHE 455 SER 456 0.0000

SER 456 PRO 457 -0.0001

PRO 457 GLU 458 0.0002

GLU 458 ASP 459 -0.0001

ASP 459 LEU 460 0.0002

LEU 460 ARG 461 -0.0006

ARG 461 SER 462 0.0001

SER 462 PHE 463 0.0002

PHE 463 GLU 464 0.0005

GLU 464 LYS 465 -0.0001

LYS 465 LYS 466 -0.1081

LYS 466 ASN 467 -0.0003

ASN 467 ARG 468 -0.0000

ARG 468 ASN 469 0.0000

ASN 469 ARG 470 0.0002

ARG 470 GLY 471 -0.0001

GLY 471 TYR 472 -0.0002

TYR 472 PHE 473 0.0001

PHE 473 SER 474 0.0003

SER 474 ASP 475 -0.0001

ASP 475 VAL 476 0.0001

VAL 476 ARG 477 0.0003

ARG 477 MET 478 -0.0002

MET 478 HIS 479 0.0001

HIS 479 PRO 480 -0.0002

PRO 480 ILE 481 -0.1952

ILE 481 ASN 482 -0.0002

ASN 482 SER 483 -0.0003

SER 483 PHE 484 0.0003

PHE 484 GLU 485 0.0001

GLU 485 LEU 486 0.0002

LEU 486 LEU 487 -0.0000

LEU 487 PHE 488 -0.0003

PHE 488 PHE 489 -0.0001

PHE 489 ALA 490 -0.0001

ALA 490 VAL 491 -0.0001

VAL 491 PHE 492 -0.0000

PHE 492 GLY 493 -0.0002

GLY 493 GLN 494 0.0003

GLN 494 THR 495 0.0001

THR 495 THR 496 -0.0881

THR 496 THR 497 -0.0002

THR 497 GLU 498 0.0001

GLU 498 GLN 499 0.0003

GLN 499 THR 500 -0.0004

THR 500 GLN 501 0.0001

GLN 501 VAL 502 -0.0003

VAL 502 ASP 503 0.0003

ASP 503 LYS 504 -0.0001

LYS 504 ILE 505 0.0000

ILE 505 LYS 506 -0.0000

LYS 506 ASN 507 -0.0001

ASN 507 VAL 508 -0.0001

VAL 508 ALA 509 0.0000

ALA 509 THR 510 -0.0002

THR 510 PRO 511 0.0892

PRO 511 THR 512 0.0001

THR 512 GLN 513 -0.0002

GLN 513 PRO 514 -0.0001

PRO 514 TYR 515 0.0001

TYR 515 TRP 516 0.0003

TRP 516 VAL 517 -0.0001

VAL 517 GLU 518 -0.0002

GLU 518 TYR 519 -0.0004

TYR 519 LEU 520 0.0000

LEU 520 PHE 521 0.0002

PHE 521 LYS 522 0.0002

LYS 522 ILE 523 -0.0000

ILE 523 VAL 524 0.0000

VAL 524 PHE 525 0.0000

PHE 525 GLY 526 0.1763

GLY 526 ILE 527 -0.0002

ILE 527 TYR 528 0.0001

TYR 528 MET 529 0.0004

MET 529 LEU 530 -0.0003

LEU 530 VAL 531 -0.0001

VAL 531 SER 532 -0.0002

SER 532 VAL 533 0.0000

VAL 533 VAL 534 0.0001

VAL 534 VAL 535 -0.0003

VAL 535 LEU 536 -0.0001

LEU 536 ILE 537 0.0004

ILE 537 ASN 538 0.0002

ASN 538 LEU 539 0.0000

LEU 539 LEU 540 -0.0002

LEU 540 ILE 541 0.0027

ILE 541 ALA 542 -0.0002

ALA 542 MET 543 -0.0002

MET 543 MET 544 -0.0000

MET 544 SER 545 0.0002

SER 545 ASP 546 0.0001

ASP 546 THR 547 -0.0001

THR 547 TYR 548 -0.0003

TYR 548 GLN 549 -0.0000

GLN 549 ARG 550 0.0001

ARG 550 ILE 551 -0.0001

ILE 551 GLN 552 -0.0002

GLN 552 ALA 553 0.0000

ALA 553 GLN 554 -0.0000

GLN 554 SER 555 0.0000

SER 555 ASP 556 0.2041

ASP 556 ILE 557 0.0001

ILE 557 GLU 558 -0.0005

GLU 558 TRP 559 -0.0002

TRP 559 LYS 560 -0.0000

LYS 560 PHE 561 0.0001

PHE 561 GLY 562 0.0002

GLY 562 LEU 563 -0.0001

LEU 563 SER 564 -0.0001

SER 564 LYS 565 0.0004

LYS 565 LEU 566 0.0001

LEU 566 ILE 567 0.0000

ILE 567 ARG 568 -0.0003

ARG 568 ASN 569 -0.0001

ASN 569 MET 570 -0.0003

MET 570 HIS 571 -0.0286

HIS 571 ARG 572 -0.0000

ARG 572 THR 573 0.0003

THR 573 THR 574 -0.0004

THR 574 THR 575 0.0002

THR 575 ALA 576 -0.0001

ALA 576 PRO 577 -0.0003

PRO 577 SER 578 0.0001

SER 578 PRO 579 0.0002

PRO 579 LEU 580 -0.0002

LEU 580 ASN 581 -0.0005

ASN 581 LEU 582 -0.0001

LEU 582 VAL 583 -0.0000

VAL 583 THR 584 0.0001

THR 584 THR 585 0.0000

THR 585 TRP 586 0.0853

TRP 586 PHE 587 -0.0000

PHE 587 MET 588 0.0000

MET 588 TRP 589 0.0000

TRP 589 ILE 590 0.0003

ILE 590 VAL 591 0.0004

VAL 591 GLU 592 0.0002

GLU 592 LYS 593 -0.0002

LYS 593 VAL 594 0.0001

VAL 594 LYS 595 0.0002

LYS 595 ALA 596 0.0003

ALA 596 ARG 597 0.0001

ARG 597 MET 598 0.0001

MET 598 LYS 599 -0.0001

LYS 599 LYS 600 0.0002

LYS 600 LYS 601 -0.0137

LYS 601 LYS 602 0.0000

LYS 602 ARG 603 0.0003

ARG 603 PRO 604 -0.0005

PRO 604 SER 605 -0.0003

SER 605 LEU 606 0.0003

LEU 606 VAL 607 -0.0002

VAL 607 GLN 608 0.0004

GLN 608 MET 609 0.0001

MET 609 MET 610 -0.0001

MET 610 GLY 611 0.0001

GLY 611 ILE 612 -0.0003

ILE 612 ARG 613 0.0001

ARG 613 GLN 614 -0.0001

GLN 614 ALA 615 -0.0000

ALA 615 SER 616 0.1708

SER 616 PRO 617 0.0001

PRO 617 ARG 618 0.0005

ARG 618 THR 619 -0.0001

THR 619 LYS 620 0.0002

LYS 620 ALA 621 -0.0000

ALA 621 GLY 622 -0.0002

GLY 622 ALA 623 -0.0002

ALA 623 LYS 624 -0.0000

LYS 624 TRP 625 -0.0001

TRP 625 LEU 626 0.0003

LEU 626 SER 627 0.0001

SER 627 LYS 628 -0.0003

LYS 628 ILE 629 -0.0002

ILE 629 LYS 630 0.0001

LYS 630 LYS 631 0.0935

LYS 631 ASP 632 0.0001

ASP 632 SER 633 -0.0002

SER 633 VAL 634 0.0000

VAL 634 ALA 635 0.0001

ALA 635 LEU 636 0.0001

LEU 636 SER 637 -0.0003

SER 637 GLN 638 -0.0001

GLN 638 VAL 639 0.0001

VAL 639 HIS 640 -0.0002

HIS 640 LEU 641 0.0002

LEU 641 SER 642 -0.0001

SER 642 PRO 643 -0.0001

PRO 643 LEU 644 0.0001

LEU 644 GLY 645 -0.0000

GLY 645 SER 646 0.2291

SER 646 GLN 647 -0.0002

GLN 647 ALA 648 0.0001

ALA 648 SER 649 -0.0005

SER 649 PHE 650 0.0001

PHE 650 SER 651 0.0001

SER 651 GLN 652 -0.0000

GLN 652 ALA 653 -0.0004

ALA 653 ASN 654 -0.0003

ASN 654 GLN 655 -0.0001

GLN 655 ASN 656 0.0002

ASN 656 ARG 657 0.0002

ARG 657 ILE 658 -0.0001

ILE 658 GLU 659 0.0003

GLU 659 ASN 660 -0.0003

ASN 660 VAL 661 -0.0919

VAL 661 ALA 662 0.0001

ALA 662 ASP 663 0.0002

ASP 663 TRP 664 0.0002

TRP 664 GLU 665 -0.0003

GLU 665 ALA 666 -0.0004

ALA 666 ILE 667 -0.0002

ILE 667 ALA 668 -0.0000

ALA 668 LYS 669 -0.0000

LYS 669 LYS 670 0.0004

LYS 670 TYR 671 -0.0001

TYR 671 ARG 672 0.0002

ARG 672 ALA 673 -0.0002

ALA 673 LEU 674 -0.0000

LEU 674 VAL 675 0.0000

VAL 675 GLY 676 -0.0998

GLY 676 ASP 677 -0.0001

ASP 677 GLU 678 0.0000

GLU 678 GLU 679 0.0002

GLU 679 GLY 680 0.0002

GLY 680 GLY 681 -0.0000

GLY 681 SER 682 0.0000

SER 682 LEU 683 -0.0000

LEU 683 LYS 684 0.0001

LYS 684 ASP 685 -0.0001

ASP 685 SER 686 0.0003

SER 686 ASP 687 0.0001

ASP 687 ALA 688 -0.0002

ALA 688 GLU 689 0.0000

GLU 689 SER 690 -0.0000

SER 690 GLY 691 -0.0353

GLY 691 SER 692 0.0000

SER 692 GLN 693 0.0002

GLN 693 GLU 694 -0.0000

GLU 694 GLY 695 0.0004

GLY 695 SER 696 -0.0002

SER 696 GLY 697 0.0001

GLY 697 GLY 698 -0.0002

GLY 698 GLN 699 -0.0002

GLN 699 GLN 700 0.0001

GLN 700 PRO 701 0.0001

PRO 701 PRO 702 -0.0001

PRO 702 ALA 703 -0.0000

ALA 703 GLN 704 0.0000

GLN 704 VAL 705 0.0000

VAL 705 GLY 706 -0.1476

GLY 706 ARG 707 -0.0003

ARG 707 ARG 708 -0.0001

ARG 708 ALA 709 -0.0001

ALA 709 ILE 710 0.0002

ILE 710 LYS 711 0.0001

LYS 711 ALA 712 -0.0001

ALA 712 THR 713 0.0002

THR 713 LEU 714 0.0003

LEU 714 ALA 715 -0.0000

ALA 715 ASP 716 0.0002

ASP 716 THR 717 -0.0003

THR 717 THR 718 -0.0002

THR 718 LYS 719 -0.0005

LYS 719 MET 1 -0.0276

MET 1 SER 2 -0.0001

SER 2 GLN 3 0.0000

GLN 3 PRO 4 -0.0001

PRO 4 ARG 5 0.0001

ARG 5 GLY 6 -0.0001

GLY 6 GLY 7 -0.0001

GLY 7 ARG 8 0.0001

ARG 8 GLY 9 -0.0001

GLY 9 GLY 10 -0.0001

GLY 10 GLY 11 0.0002

GLY 11 ARG 12 -0.0001

ARG 12 GLY 13 0.0000

GLY 13 GLY 14 0.0004

GLY 14 GLY 15 -0.0003

GLY 15 VAL 16 -0.0259

VAL 16 GLY 17 0.0001

GLY 17 ARG 18 0.0002

ARG 18 LYS 19 -0.0001

LYS 19 THR 20 0.0001

THR 20 PRO 21 -0.0001

PRO 21 SER 22 -0.0003

SER 22 SER 23 0.0004

SER 23 LEU 24 -0.0002

LEU 24 THR 25 0.0001

THR 25 GLY 26 -0.0003

GLY 26 PRO 27 -0.0001

PRO 27 PRO 28 -0.0000

PRO 28 ASP 29 0.0000

ASP 29 GLU 30 -0.0003

GLU 30 SER 31 0.0072

SER 31 ALA 32 -0.0005

ALA 32 THR 33 0.0002

THR 33 PRO 34 0.0002

PRO 34 SER 35 -0.0004

SER 35 GLU 36 0.0000

GLU 36 ARG 37 0.0005

ARG 37 ALA 38 -0.0002

ALA 38 THR 39 0.0000

THR 39 PRO 40 0.0001

PRO 40 ALA 41 0.0000

ALA 41 SER 42 -0.0000

SER 42 LYS 43 0.0001

LYS 43 ALA 44 -0.0005

ALA 44 ASP 45 0.0002

ASP 45 SER 46 0.0010

SER 46 ASP 47 0.0001

ASP 47 PRO 48 0.0002

PRO 48 LYS 49 -0.0003

LYS 49 ASP 50 -0.0000

ASP 50 ASP 51 0.0001

ASP 51 SER 52 0.0003

SER 52 SER 53 -0.0004

SER 53 SER 54 -0.0001

SER 54 ASN 55 0.0000

ASN 55 GLY 56 -0.0001

GLY 56 ASP 57 -0.0002

ASP 57 LYS 58 -0.0000

LYS 58 LYS 59 -0.0002

LYS 59 ASP 60 -0.0003

ASP 60 MET 61 -0.0599

MET 61 ASP 62 0.0002

ASP 62 LEU 63 0.0000

LEU 63 PHE 64 -0.0001

PHE 64 PRO 65 0.0000

PRO 65 ALA 66 0.0000

ALA 66 PRO 67 0.0001

PRO 67 LYS 68 0.0003

LYS 68 PRO 69 -0.0003

PRO 69 PRO 70 -0.0002

PRO 70 SER 71 -0.0002

SER 71 ALA 72 0.0001

ALA 72 GLY 73 0.0001

GLY 73 ALA 74 -0.0002

ALA 74 SER 75 -0.0000

SER 75 ILE 76 -0.1544

ILE 76 ARG 77 -0.0002

ARG 77 ASP 78 -0.0000

ASP 78 THR 79 -0.0001

THR 79 ALA 80 -0.0000

ALA 80 ASN 81 -0.0000

ASN 81 LYS 82 0.0001

LYS 82 VAL 83 0.0003

VAL 83 LEU 84 0.0001

LEU 84 GLY 85 -0.0002

GLY 85 LEU 86 -0.0000

LEU 86 ALA 87 0.0000

ALA 87 MET 88 0.0001

MET 88 LYS 89 0.0001

LYS 89 SER 90 -0.0000

SER 90 GLU 91 -0.0463

GLU 91 TRP 92 0.0003

TRP 92 THR 93 -0.0001

THR 93 PRO 94 0.0001

PRO 94 ILE 95 -0.0001

ILE 95 GLU 96 -0.0002

GLU 96 ALA 97 0.0002

ALA 97 GLU 98 0.0000

GLU 98 LEU 99 0.0002

LEU 99 LYS 100 -0.0001

LYS 100 LYS 101 0.0004

LYS 101 LEU 102 0.0000

LEU 102 GLU 103 0.0003

GLU 103 LYS 104 0.0001

LYS 104 TYR 105 -0.0001

TYR 105 VAL 106 0.0115

VAL 106 ALA 107 0.0001

ALA 107 ASN 108 0.0001

ASN 108 VAL 109 0.0000

VAL 109 GLY 110 0.0000

GLY 110 GLU 111 -0.0003

GLU 111 ASP 112 -0.0001

ASP 112 GLY 113 -0.0000

GLY 113 ASN 114 -0.0002

ASN 114 HIS 115 0.0000

HIS 115 ILE 116 0.0001

ILE 116 PRO 117 0.0002

PRO 117 LEU 118 -0.0001

LEU 118 ALA 119 0.0000

ALA 119 GLY 120 -0.0004

GLY 120 VAL 121 -0.0093

VAL 121 HIS 122 -0.0003

HIS 122 ASP 123 -0.0002

ASP 123 MET 124 0.0001

MET 124 ASN 125 -0.0002

ASN 125 LEU 126 0.0002

LEU 126 MET 127 -0.0003

MET 127 GLU 128 -0.0003

GLU 128 ASP 129 0.0006

ASP 129 LYS 130 0.0000

LYS 130 ARG 131 0.0001

ARG 131 PHE 132 0.0001

PHE 132 VAL 133 0.0003

VAL 133 TYR 134 -0.0001

TYR 134 ASN 135 -0.0001

ASN 135 LEU 136 0.0094

LEU 136 MET 137 -0.0002

MET 137 VAL 138 -0.0002

VAL 138 VAL 139 0.0000

VAL 139 SER 140 0.0001

SER 140 LYS 141 0.0004

LYS 141 ASN 142 -0.0002

ASN 142 HIS 143 0.0000

HIS 143 ASN 144 -0.0000

ASN 144 ASN 145 -0.0000

ASN 145 LYS 146 -0.0003

LYS 146 PRO 147 -0.0001

PRO 147 ILE 148 0.0004

ILE 148 GLN 149 -0.0001

GLN 149 GLU 150 -0.0001

GLU 150 PHE 151 0.0171

PHE 151 VAL 152 0.0000

VAL 152 LEU 153 0.0003

LEU 153 VAL 154 -0.0001

VAL 154 SER 155 -0.0002

SER 155 PRO 156 -0.0000

PRO 156 ALA 157 -0.0000

ALA 157 PRO 158 0.0001

PRO 158 VAL 159 0.0001

VAL 159 ASP 160 0.0004

ASP 160 THR 161 -0.0002

THR 161 ALA 162 -0.0002

ALA 162 ALA 163 0.0001

ALA 163 LYS 164 0.0001

LYS 164 LEU 165 0.0001

LEU 165 SER 166 0.1018

SER 166 ASN 167 0.0001

ASN 167 ILE 168 0.0004

ILE 168 TYR 169 -0.0001

TYR 169 ILE 170 -0.0001

ILE 170 VAL 171 0.0002

VAL 171 LEU 172 -0.0000

LEU 172 SER 173 0.0001

SER 173 THR 174 -0.0004

THR 174 LYS 175 -0.0002

LYS 175 GLU 176 0.0004

GLU 176 LYS 177 0.0000

LYS 177 GLU 178 0.0002

GLU 178 ARG 179 -0.0002

ARG 179 ALA 180 -0.0000

ALA 180 LYS 181 0.0622

LYS 181 ASP 182 -0.0001

ASP 182 LEU 183 -0.0000

LEU 183 VAL 184 0.0003

VAL 184 ALA 185 -0.0002

ALA 185 ALA 186 -0.0004

ALA 186 GLY 187 -0.0001

GLY 187 LYS 188 -0.0002

LYS 188 GLN 189 0.0001

GLN 189 CYS 190 0.0002

CYS 190 GLU 191 0.0001

GLU 191 ALA 192 0.0002

ALA 192 MET 193 0.0000

MET 193 ALA 194 -0.0002

ALA 194 THR 195 0.0003

THR 195 GLU 196 0.0413

GLU 196 LEU 197 0.0001

LEU 197 LEU 198 -0.0002

LEU 198 ALA 199 0.0003

ALA 199 LEU 200 -0.0001

LEU 200 ALA 201 0.0001

ALA 201 ALA 202 -0.0002

ALA 202 GLY 203 -0.0002

GLY 203 SER 204 -0.0001

SER 204 ASP 205 0.0004

ASP 205 SER 206 -0.0003

SER 206 ALA 207 -0.0000

ALA 207 GLY 208 0.0002

GLY 208 LYS 209 0.0004

LYS 209 ILE 210 0.0001

ILE 210 LEU 211 0.1041

LEU 211 GLN 212 -0.0002

GLN 212 ALA 213 -0.0003

ALA 213 THR 214 0.0005

THR 214 ASP 215 -0.0003

ASP 215 LYS 216 -0.0003

LYS 216 ARG 217 -0.0003

ARG 217 ASN 218 0.0001

ASN 218 VAL 219 -0.0001

VAL 219 GLU 220 0.0004

GLU 220 PHE 221 0.0002

PHE 221 LEU 222 -0.0000

LEU 222 ASP 223 -0.0004

ASP 223 VAL 224 0.0001

VAL 224 LEU 225 -0.0000

LEU 225 ILE 226 -0.1765

ILE 226 GLU 227 0.0003

GLU 227 ASN 228 -0.0001

ASN 228 GLU 229 -0.0003

GLU 229 GLN 230 0.0002

GLN 230 LYS 231 -0.0003

LYS 231 GLU 232 -0.0003

GLU 232 VAL 233 0.0002

VAL 233 ILE 234 -0.0004

ILE 234 ALA 235 0.0002

ALA 235 HIS 236 0.0002

HIS 236 THR 237 -0.0003

THR 237 VAL 238 -0.0000

VAL 238 VAL 239 0.0001

VAL 239 GLN 240 0.0001

GLN 240 ARG 241 -0.0532

ARG 241 TYR 242 -0.0000

TYR 242 LEU 243 -0.0001

LEU 243 GLN 244 -0.0003

GLN 244 GLU 245 -0.0003

GLU 245 LEU 246 -0.0000

LEU 246 TRP 247 0.0000

TRP 247 HIS 248 -0.0001

HIS 248 GLY 249 -0.0003

GLY 249 SER 250 -0.0003

SER 250 LEU 251 -0.0003

LEU 251 THR 252 -0.0002

THR 252 TRP 253 0.0002

TRP 253 ALA 254 0.0001

ALA 254 SER 255 -0.0001

SER 255 TRP 256 -0.0424

TRP 256 LYS 257 0.0001

LYS 257 ILE 258 0.0000

ILE 258 LEU 259 0.0000

LEU 259 LEU 260 0.0000

LEU 260 LEU 261 -0.0001

LEU 261 LEU 262 0.0002

LEU 262 VAL 263 0.0000

VAL 263 ALA 264 -0.0002

ALA 264 PHE 265 0.0001

PHE 265 ILE 266 -0.0002

ILE 266 VAL 267 0.0001

VAL 267 CYS 268 -0.0001

CYS 268 PRO 269 0.0000

PRO 269 PRO 270 0.0004

PRO 270 VAL 271 0.0556

VAL 271 TRP 272 -0.0001

TRP 272 ILE 273 -0.0000

ILE 273 GLY 274 -0.0001

GLY 274 PHE 275 -0.0002

PHE 275 THR 276 0.0004

THR 276 PHE 277 0.0001

PHE 277 PRO 278 0.0000

PRO 278 MET 279 -0.0002

MET 279 GLY 280 0.0001

GLY 280 HIS 281 0.0003

HIS 281 LYS 282 0.0003

LYS 282 PHE 283 0.0005

PHE 283 ASN 284 -0.0002

ASN 284 LYS 285 0.0004

LYS 285 VAL 286 -0.0105

VAL 286 PRO 287 -0.0000

PRO 287 ILE 288 -0.0001

ILE 288 ILE 289 0.0000

ILE 289 LYS 290 0.0003

LYS 290 PHE 291 0.0003

PHE 291 MET 292 0.0001

MET 292 SER 293 -0.0002

SER 293 TYR 294 -0.0001

TYR 294 LEU 295 0.0001

LEU 295 THR 296 -0.0001

THR 296 SER 297 -0.0001

SER 297 HIS 298 -0.0001

HIS 298 ILE 299 -0.0006

ILE 299 TYR 300 -0.0001

TYR 300 LEU 301 -0.1176

LEU 301 MET 302 0.0003

MET 302 ILE 303 0.0001

ILE 303 HIS 304 0.0001

HIS 304 LEU 305 -0.0001

LEU 305 SER 306 -0.0003

SER 306 ILE 307 -0.0000

ILE 307 VAL 308 0.0000

VAL 308 GLY 309 0.0000

GLY 309 ILE 310 -0.0000

ILE 310 THR 311 0.0000

THR 311 PRO 312 -0.0001

PRO 312 ILE 313 -0.0002

ILE 313 TYR 314 -0.0001

TYR 314 PRO 315 -0.0003

PRO 315 VAL 316 -0.0248

VAL 316 LEU 317 -0.0002

LEU 317 ARG 318 -0.0000

ARG 318 LEU 319 0.0001

LEU 319 SER 320 0.0002

SER 320 LEU 321 -0.0004

LEU 321 VAL 322 0.0001

VAL 322 PRO 323 -0.0003

PRO 323 TYR 324 -0.0002

TYR 324 TRP 325 0.0004

TRP 325 TYR 326 -0.0000

TYR 326 GLU 327 -0.0002

GLU 327 VAL 328 0.0000

VAL 328 GLY 329 0.0003

GLY 329 LEU 330 -0.0004

LEU 330 LEU 331 0.0491

LEU 331 ILE 332 0.0001

ILE 332 TRP 333 0.0003

TRP 333 LEU 334 0.0003

LEU 334 SER 335 -0.0002

SER 335 GLY 336 -0.0003

GLY 336 LEU 337 0.0000

LEU 337 LEU 338 -0.0001

LEU 338 LEU 339 0.0000

LEU 339 PHE 340 -0.0000

PHE 340 GLU 341 -0.0001

GLU 341 LEU 342 -0.0002

LEU 342 THR 343 0.0001

THR 343 ASN 344 0.0000

ASN 344 PRO 345 0.0002

PRO 345 SER 346 -0.0821

SER 346 ASP 347 -0.0001

ASP 347 LYS 348 0.0000

LYS 348 SER 349 0.0004

SER 349 GLY 350 -0.0002

GLY 350 LEU 351 0.0001

LEU 351 GLY 352 0.0003

GLY 352 SER 353 0.0001

SER 353 ILE 354 -0.0001

ILE 354 LYS 355 -0.0002

LYS 355 VAL 356 0.0000

VAL 356 LEU 357 -0.0002

LEU 357 VAL 358 -0.0001

VAL 358 LEU 359 0.0004

LEU 359 LEU 360 0.0003

LEU 360 LEU 361 -0.0203

LEU 361 GLY 362 -0.0000

GLY 362 MET 363 0.0002

MET 363 ALA 364 -0.0001

ALA 364 GLY 365 0.0004

GLY 365 VAL 366 0.0002

VAL 366 GLY 367 -0.0000

GLY 367 VAL 368 -0.0000

VAL 368 HIS 369 -0.0001

HIS 369 VAL 370 0.0001

VAL 370 SER 371 -0.0000

SER 371 ALA 372 -0.0001

ALA 372 PHE 373 0.0003

PHE 373 LEU 374 -0.0001

LEU 374 PHE 375 0.0000

PHE 375 VAL 376 -0.0339

VAL 376 SER 377 -0.0001

SER 377 LYS 378 -0.0000

LYS 378 GLU 379 -0.0001

GLU 379 TYR 380 -0.0000

TYR 380 TRP 381 0.0003

TRP 381 PRO 382 -0.0000

PRO 382 THR 383 0.0002

THR 383 LEU 384 0.0004

LEU 384 VAL 385 -0.0001

VAL 385 TYR 386 -0.0001

TYR 386 CYS 387 -0.0000

CYS 387 ARG 388 -0.0000

ARG 388 ASN 389 0.0002

ASN 389 GLN 390 0.0002

GLN 390 CYS 391 -0.0157

CYS 391 PHE 392 -0.0003

PHE 392 ALA 393 0.0001

ALA 393 LEU 394 0.0001

LEU 394 ALA 395 -0.0001

ALA 395 PHE 396 0.0000

PHE 396 LEU 397 -0.0002

LEU 397 LEU 398 -0.0001

LEU 398 ALA 399 0.0002

ALA 399 CYS 400 0.0001

CYS 400 VAL 401 -0.0000

VAL 401 GLN 402 -0.0002

GLN 402 ILE 403 -0.0002

ILE 403 LEU 404 0.0002

LEU 404 ASP 405 0.0001

ASP 405 PHE 406 0.0391

PHE 406 LEU 407 0.0004

LEU 407 SER 408 -0.0002

SER 408 PHE 409 0.0001

PHE 409 HIS 410 -0.0000

HIS 410 HIS 411 0.0002

HIS 411 LEU 412 0.0003

LEU 412 PHE 413 -0.0002

PHE 413 GLY 414 -0.0002

GLY 414 PRO 415 0.0003

PRO 415 TRP 416 -0.0001

TRP 416 ALA 417 0.0003

ALA 417 ILE 418 0.0001

ILE 418 ILE 419 0.0001

ILE 419 ILE 420 0.0003

ILE 420 GLY 421 0.1398

GLY 421 ASP 422 0.0000

ASP 422 LEU 423 -0.0002

LEU 423 LEU 424 0.0001

LEU 424 LYS 425 -0.0003

LYS 425 ASP 426 -0.0003

ASP 426 LEU 427 0.0001

LEU 427 ALA 428 -0.0001

ALA 428 ARG 429 0.0001

ARG 429 PHE 430 -0.0002

PHE 430 LEU 431 0.0002

LEU 431 ALA 432 -0.0002

ALA 432 VAL 433 0.0000

VAL 433 LEU 434 0.0000

LEU 434 ALA 435 0.0001

ALA 435 ILE 436 -0.2833

ILE 436 PHE 437 -0.0001

PHE 437 VAL 438 0.0001

VAL 438 PHE 439 -0.0001

PHE 439 GLY 440 0.0001

GLY 440 PHE 441 0.0001

PHE 441 SER 442 -0.0001

SER 442 MET 443 0.0001

MET 443 HIS 444 -0.0001

HIS 444 ILE 445 0.0001

ILE 445 VAL 446 0.0001

VAL 446 ALA 447 -0.0002

ALA 447 LEU 448 -0.0004

LEU 448 ASN 449 0.0001

ASN 449 GLN 450 0.0002

GLN 450 SER 451 -0.0652

SER 451 PHE 452 -0.0001

PHE 452 ALA 453 0.0001

ALA 453 ASN 454 0.0002

ASN 454 PHE 455 -0.0002

PHE 455 SER 456 0.0002

SER 456 PRO 457 -0.0003

PRO 457 GLU 458 -0.0001

GLU 458 ASP 459 -0.0002

ASP 459 LEU 460 0.0001

LEU 460 ARG 461 -0.0004

ARG 461 SER 462 -0.0002

SER 462 PHE 463 0.0002

PHE 463 GLU 464 -0.0002

GLU 464 LYS 465 0.0004

LYS 465 LYS 466 -0.2011

LYS 466 ASN 467 -0.0001

ASN 467 ARG 468 -0.0001

ARG 468 ASN 469 0.0000

ASN 469 ARG 470 0.0005

ARG 470 GLY 471 -0.0004

GLY 471 TYR 472 0.0001

TYR 472 PHE 473 -0.0002

PHE 473 SER 474 0.0002

SER 474 ASP 475 0.0003

ASP 475 VAL 476 -0.0000

VAL 476 ARG 477 0.0000

ARG 477 MET 478 0.0003

MET 478 HIS 479 0.0002

HIS 479 PRO 480 -0.0003

PRO 480 ILE 481 -0.2275

ILE 481 ASN 482 -0.0001

ASN 482 SER 483 -0.0002

SER 483 PHE 484 -0.0003

PHE 484 GLU 485 0.0000

GLU 485 LEU 486 0.0005

LEU 486 LEU 487 -0.0001

LEU 487 PHE 488 -0.0001

PHE 488 PHE 489 -0.0001

PHE 489 ALA 490 0.0004

ALA 490 VAL 491 -0.0001

VAL 491 PHE 492 -0.0001

PHE 492 GLY 493 -0.0001

GLY 493 GLN 494 0.0003

GLN 494 THR 495 -0.0002

THR 495 THR 496 0.0204

THR 496 THR 497 0.0002

THR 497 GLU 498 -0.0001

GLU 498 GLN 499 -0.0001

GLN 499 THR 500 0.0002

THR 500 GLN 501 -0.0001

GLN 501 VAL 502 0.0002

VAL 502 ASP 503 0.0001

ASP 503 LYS 504 -0.0002

LYS 504 ILE 505 -0.0002

ILE 505 LYS 506 0.0002

LYS 506 ASN 507 0.0001

ASN 507 VAL 508 -0.0004

VAL 508 ALA 509 -0.0001

ALA 509 THR 510 -0.0001

THR 510 PRO 511 0.0845

PRO 511 THR 512 -0.0001

THR 512 GLN 513 -0.0001

GLN 513 PRO 514 0.0001

PRO 514 TYR 515 0.0002

TYR 515 TRP 516 0.0000

TRP 516 VAL 517 0.0003

VAL 517 GLU 518 0.0004

GLU 518 TYR 519 -0.0001

TYR 519 LEU 520 0.0005

LEU 520 PHE 521 0.0001

PHE 521 LYS 522 0.0001

LYS 522 ILE 523 -0.0003

ILE 523 VAL 524 -0.0001

VAL 524 PHE 525 0.0002

PHE 525 GLY 526 0.0981

GLY 526 ILE 527 0.0005

ILE 527 TYR 528 -0.0000

TYR 528 MET 529 0.0004

MET 529 LEU 530 -0.0000

LEU 530 VAL 531 0.0001

VAL 531 SER 532 -0.0000

SER 532 VAL 533 -0.0001

VAL 533 VAL 534 0.0000

VAL 534 VAL 535 0.0000

VAL 535 LEU 536 0.0001

LEU 536 ILE 537 0.0002

ILE 537 ASN 538 0.0001

ASN 538 LEU 539 0.0002

LEU 539 LEU 540 0.0000

LEU 540 ILE 541 -0.0350

ILE 541 ALA 542 0.0001

ALA 542 MET 543 0.0000

MET 543 MET 544 -0.0004

MET 544 SER 545 -0.0003

SER 545 ASP 546 0.0001

ASP 546 THR 547 -0.0003

THR 547 TYR 548 0.0003

TYR 548 GLN 549 -0.0002

GLN 549 ARG 550 0.0002

ARG 550 ILE 551 0.0003

ILE 551 GLN 552 -0.0005

GLN 552 ALA 553 -0.0001

ALA 553 GLN 554 0.0002

GLN 554 SER 555 -0.0002

SER 555 ASP 556 -0.1857

ASP 556 ILE 557 -0.0000

ILE 557 GLU 558 -0.0000

GLU 558 TRP 559 -0.0000

TRP 559 LYS 560 0.0003

LYS 560 PHE 561 0.0003

PHE 561 GLY 562 0.0001

GLY 562 LEU 563 0.0003

LEU 563 SER 564 0.0001

SER 564 LYS 565 -0.0002

LYS 565 LEU 566 0.0001

LEU 566 ILE 567 -0.0001

ILE 567 ARG 568 -0.0001

ARG 568 ASN 569 -0.0002

ASN 569 MET 570 0.0001

MET 570 HIS 571 -0.1266

HIS 571 ARG 572 -0.0001

ARG 572 THR 573 0.0005

THR 573 THR 574 0.0000

THR 574 THR 575 -0.0001

THR 575 ALA 576 -0.0002

ALA 576 PRO 577 0.0004

PRO 577 SER 578 0.0002

SER 578 PRO 579 -0.0002

PRO 579 LEU 580 -0.0001

LEU 580 ASN 581 0.0002

ASN 581 LEU 582 0.0000

LEU 582 VAL 583 0.0000

VAL 583 THR 584 0.0002

THR 584 THR 585 -0.0000

THR 585 TRP 586 0.3791

TRP 586 PHE 587 -0.0003

PHE 587 MET 588 0.0000

MET 588 TRP 589 -0.0002

TRP 589 ILE 590 0.0001

ILE 590 VAL 591 -0.0002

VAL 591 GLU 592 -0.0001

GLU 592 LYS 593 -0.0001

LYS 593 VAL 594 0.0001

VAL 594 LYS 595 0.0002

LYS 595 ALA 596 0.0002

ALA 596 ARG 597 0.0002

ARG 597 MET 598 0.0002

MET 598 LYS 599 -0.0001

LYS 599 LYS 600 -0.0003

LYS 600 LYS 601 -0.0118

LYS 601 LYS 602 0.0002

LYS 602 ARG 603 0.0001

ARG 603 PRO 604 -0.0002

PRO 604 SER 605 -0.0000

SER 605 LEU 606 0.0001

LEU 606 VAL 607 0.0002

VAL 607 GLN 608 0.0001

GLN 608 MET 609 0.0002

MET 609 MET 610 0.0004

MET 610 GLY 611 -0.0000

GLY 611 ILE 612 0.0001

ILE 612 ARG 613 0.0002

ARG 613 GLN 614 0.0001

GLN 614 ALA 615 -0.0001

ALA 615 SER 616 0.0071

SER 616 PRO 617 0.0001

PRO 617 ARG 618 -0.0002

ARG 618 THR 619 0.0000

THR 619 LYS 620 0.0001

LYS 620 ALA 621 0.0002

ALA 621 GLY 622 -0.0001

GLY 622 ALA 623 -0.0002

ALA 623 LYS 624 -0.0002

LYS 624 TRP 625 -0.0000

TRP 625 LEU 626 0.0001

LEU 626 SER 627 0.0002

SER 627 LYS 628 0.0002

LYS 628 ILE 629 0.0002

ILE 629 LYS 630 -0.0001

LYS 630 LYS 631 0.0531

LYS 631 ASP 632 0.0002

ASP 632 SER 633 -0.0003

SER 633 VAL 634 -0.0001

VAL 634 ALA 635 0.0001

ALA 635 LEU 636 -0.0002

LEU 636 SER 637 -0.0003

SER 637 GLN 638 0.0000

GLN 638 VAL 639 -0.0000

VAL 639 HIS 640 0.0002

HIS 640 LEU 641 -0.0001

LEU 641 SER 642 0.0001

SER 642 PRO 643 -0.0003

PRO 643 LEU 644 -0.0000

LEU 644 GLY 645 0.0000

GLY 645 SER 646 -0.0189

SER 646 GLN 647 0.0003

GLN 647 ALA 648 -0.0000

ALA 648 SER 649 0.0000

SER 649 PHE 650 0.0001

PHE 650 SER 651 -0.0002

SER 651 GLN 652 0.0001

GLN 652 ALA 653 -0.0000

ALA 653 ASN 654 -0.0002

ASN 654 GLN 655 0.0003

GLN 655 ASN 656 0.0001

ASN 656 ARG 657 0.0002

ARG 657 ILE 658 -0.0000

ILE 658 GLU 659 0.0000

GLU 659 ASN 660 0.0004

ASN 660 VAL 661 0.0192

VAL 661 ALA 662 0.0000

ALA 662 ASP 663 0.0001

ASP 663 TRP 664 0.0001

TRP 664 GLU 665 -0.0002

GLU 665 ALA 666 0.0002

ALA 666 ILE 667 0.0002

ILE 667 ALA 668 -0.0001

ALA 668 LYS 669 0.0003

LYS 669 LYS 670 0.0001

LYS 670 TYR 671 -0.0001

TYR 671 ARG 672 -0.0004

ARG 672 ALA 673 0.0002

ALA 673 LEU 674 -0.0000

LEU 674 VAL 675 -0.0001

VAL 675 GLY 676 0.0865

GLY 676 ASP 677 0.0001

ASP 677 GLU 678 0.0003

GLU 678 GLU 679 -0.0001

GLU 679 GLY 680 -0.0000

GLY 680 GLY 681 -0.0001

GLY 681 SER 682 -0.0002

SER 682 LEU 683 -0.0002

LEU 683 LYS 684 -0.0002

LYS 684 ASP 685 -0.0001

ASP 685 SER 686 -0.0000

SER 686 ASP 687 0.0004

ASP 687 ALA 688 -0.0000

ALA 688 GLU 689 0.0000

GLU 689 SER 690 0.0000

SER 690 GLY 691 -0.0645

GLY 691 SER 692 0.0001

SER 692 GLN 693 0.0001

GLN 693 GLU 694 -0.0003

GLU 694 GLY 695 0.0000

GLY 695 SER 696 -0.0001

SER 696 GLY 697 -0.0000

GLY 697 GLY 698 0.0001

GLY 698 GLN 699 -0.0000

GLN 699 GLN 700 0.0003

GLN 700 PRO 701 0.0002

PRO 701 PRO 702 -0.0003

PRO 702 ALA 703 -0.0004

ALA 703 GLN 704 0.0001

GLN 704 VAL 705 -0.0001

VAL 705 GLY 706 -0.2070

GLY 706 ARG 707 -0.0001

ARG 707 ARG 708 0.0001

ARG 708 ALA 709 0.0001

ALA 709 ILE 710 -0.0001

ILE 710 LYS 711 -0.0000

LYS 711 ALA 712 0.0001

ALA 712 THR 713 -0.0001

THR 713 LEU 714 -0.0000

LEU 714 ALA 715 -0.0002

ALA 715 ASP 716 0.0002

ASP 716 THR 717 -0.0002

THR 717 THR 718 0.0002

THR 718 LYS 719 -0.0003

LYS 719 MET 1 -0.0887

MET 1 SER 2 -0.0000

SER 2 GLN 3 0.0003

GLN 3 PRO 4 -0.0004

PRO 4 ARG 5 0.0004

ARG 5 GLY 6 -0.0001

GLY 6 GLY 7 0.0001

GLY 7 ARG 8 0.0000

ARG 8 GLY 9 0.0003

GLY 9 GLY 10 0.0000

GLY 10 GLY 11 -0.0000

GLY 11 ARG 12 -0.0002

ARG 12 GLY 13 0.0001

GLY 13 GLY 14 -0.0000

GLY 14 GLY 15 0.0001

GLY 15 VAL 16 0.0067

VAL 16 GLY 17 0.0005

GLY 17 ARG 18 -0.0004

ARG 18 LYS 19 0.0003

LYS 19 THR 20 -0.0002

THR 20 PRO 21 0.0002

PRO 21 SER 22 0.0001

SER 22 SER 23 0.0001

SER 23 LEU 24 0.0001

LEU 24 THR 25 0.0005

THR 25 GLY 26 -0.0002

GLY 26 PRO 27 -0.0002

PRO 27 PRO 28 -0.0001

PRO 28 ASP 29 0.0001

ASP 29 GLU 30 0.0000

GLU 30 SER 31 0.0051

SER 31 ALA 32 -0.0001

ALA 32 THR 33 -0.0001

THR 33 PRO 34 -0.0001

PRO 34 SER 35 0.0005

SER 35 GLU 36 -0.0005

GLU 36 ARG 37 0.0002

ARG 37 ALA 38 -0.0002

ALA 38 THR 39 0.0003

THR 39 PRO 40 -0.0001

PRO 40 ALA 41 0.0002

ALA 41 SER 42 0.0000

SER 42 LYS 43 -0.0002

LYS 43 ALA 44 0.0001

ALA 44 ASP 45 -0.0003

ASP 45 SER 46 0.0412

SER 46 ASP 47 0.0003

ASP 47 PRO 48 -0.0002

PRO 48 LYS 49 0.0001

LYS 49 ASP 50 0.0002

ASP 50 ASP 51 0.0000

ASP 51 SER 52 -0.0003

SER 52 SER 53 -0.0000

SER 53 SER 54 0.0000

SER 54 ASN 55 -0.0005

ASN 55 GLY 56 -0.0002

GLY 56 ASP 57 -0.0000

ASP 57 LYS 58 0.0002

LYS 58 LYS 59 0.0001

LYS 59 ASP 60 0.0002

ASP 60 MET 61 0.0141

MET 61 ASP 62 0.0004

ASP 62 LEU 63 -0.0003

LEU 63 PHE 64 0.0000

PHE 64 PRO 65 -0.0003

PRO 65 ALA 66 0.0001

ALA 66 PRO 67 0.0001

PRO 67 LYS 68 -0.0001

LYS 68 PRO 69 0.0000

PRO 69 PRO 70 0.0002

PRO 70 SER 71 -0.0003

SER 71 ALA 72 0.0002

ALA 72 GLY 73 0.0001

GLY 73 ALA 74 0.0002

ALA 74 SER 75 -0.0002

SER 75 ILE 76 0.1341

ILE 76 ARG 77 -0.0000

ARG 77 ASP 78 0.0000

ASP 78 THR 79 -0.0002

THR 79 ALA 80 -0.0000

ALA 80 ASN 81 -0.0000

ASN 81 LYS 82 0.0001

LYS 82 VAL 83 -0.0004

VAL 83 LEU 84 0.0003

LEU 84 GLY 85 0.0001

GLY 85 LEU 86 0.0002

LEU 86 ALA 87 -0.0001

ALA 87 MET 88 -0.0000

MET 88 LYS 89 0.0002

LYS 89 SER 90 0.0001

SER 90 GLU 91 -0.0049

GLU 91 TRP 92 0.0002

TRP 92 THR 93 -0.0001

THR 93 PRO 94 0.0004

PRO 94 ILE 95 -0.0001

ILE 95 GLU 96 -0.0002

GLU 96 ALA 97 0.0002

ALA 97 GLU 98 0.0001

GLU 98 LEU 99 -0.0002

LEU 99 LYS 100 -0.0000

LYS 100 LYS 101 -0.0002

LYS 101 LEU 102 0.0000

LEU 102 GLU 103 -0.0001

GLU 103 LYS 104 -0.0002

LYS 104 TYR 105 0.0001

TYR 105 VAL 106 0.0382

VAL 106 ALA 107 -0.0002

ALA 107 ASN 108 -0.0002

ASN 108 VAL 109 -0.0003

VAL 109 GLY 110 0.0001

GLY 110 GLU 111 0.0002

GLU 111 ASP 112 -0.0001

ASP 112 GLY 113 -0.0002

GLY 113 ASN 114 0.0001

ASN 114 HIS 115 0.0001

HIS 115 ILE 116 -0.0002

ILE 116 PRO 117 0.0003

PRO 117 LEU 118 -0.0003

LEU 118 ALA 119 -0.0000

ALA 119 GLY 120 -0.0003

GLY 120 VAL 121 -0.0881

VAL 121 HIS 122 -0.0003

HIS 122 ASP 123 -0.0001

ASP 123 MET 124 0.0002

MET 124 ASN 125 -0.0003

ASN 125 LEU 126 -0.0003

LEU 126 MET 127 0.0001

MET 127 GLU 128 0.0001

GLU 128 ASP 129 0.0002

ASP 129 LYS 130 -0.0000

LYS 130 ARG 131 0.0001

ARG 131 PHE 132 0.0002

PHE 132 VAL 133 0.0001

VAL 133 TYR 134 0.0001

TYR 134 ASN 135 0.0001

ASN 135 LEU 136 0.0140

LEU 136 MET 137 -0.0002

MET 137 VAL 138 0.0003

VAL 138 VAL 139 0.0001

VAL 139 SER 140 0.0004

SER 140 LYS 141 -0.0001

LYS 141 ASN 142 -0.0002

ASN 142 HIS 143 0.0003

HIS 143 ASN 144 -0.0000

ASN 144 ASN 145 0.0002

ASN 145 LYS 146 -0.0001

LYS 146 PRO 147 -0.0001

PRO 147 ILE 148 0.0000

ILE 148 GLN 149 0.0003

GLN 149 GLU 150 0.0001

GLU 150 PHE 151 0.0374

PHE 151 VAL 152 0.0003

VAL 152 LEU 153 -0.0002

LEU 153 VAL 154 -0.0001

VAL 154 SER 155 0.0000

SER 155 PRO 156 0.0002

PRO 156 ALA 157 -0.0000

ALA 157 PRO 158 0.0002

PRO 158 VAL 159 0.0000

VAL 159 ASP 160 0.0001

ASP 160 THR 161 0.0001

THR 161 ALA 162 -0.0001

ALA 162 ALA 163 0.0002

ALA 163 LYS 164 -0.0001

LYS 164 LEU 165 0.0000

LEU 165 SER 166 -0.0012

SER 166 ASN 167 0.0002

ASN 167 ILE 168 -0.0001

ILE 168 TYR 169 0.0000

TYR 169 ILE 170 0.0002

ILE 170 VAL 171 0.0004

VAL 171 LEU 172 -0.0002

LEU 172 SER 173 0.0002

SER 173 THR 174 -0.0003

THR 174 LYS 175 -0.0001

LYS 175 GLU 176 0.0004

GLU 176 LYS 177 -0.0001

LYS 177 GLU 178 -0.0003

GLU 178 ARG 179 -0.0001

ARG 179 ALA 180 0.0001

ALA 180 LYS 181 0.1101

LYS 181 ASP 182 -0.0002

ASP 182 LEU 183 0.0005

LEU 183 VAL 184 -0.0001

VAL 184 ALA 185 0.0003

ALA 185 ALA 186 0.0001

ALA 186 GLY 187 -0.0002

GLY 187 LYS 188 -0.0002

LYS 188 GLN 189 -0.0001

GLN 189 CYS 190 0.0002

CYS 190 GLU 191 0.0002

GLU 191 ALA 192 -0.0000

ALA 192 MET 193 -0.0002

MET 193 ALA 194 0.0001

ALA 194 THR 195 0.0003

THR 195 GLU 196 -0.0356

GLU 196 LEU 197 0.0001

LEU 197 LEU 198 0.0004

LEU 198 ALA 199 0.0001

ALA 199 LEU 200 0.0004

LEU 200 ALA 201 -0.0003

ALA 201 ALA 202 0.0001

ALA 202 GLY 203 -0.0001

GLY 203 SER 204 -0.0001

SER 204 ASP 205 -0.0003

ASP 205 SER 206 0.0002

SER 206 ALA 207 -0.0000

ALA 207 GLY 208 -0.0002

GLY 208 LYS 209 -0.0000

LYS 209 ILE 210 0.0004

ILE 210 LEU 211 0.0687

LEU 211 GLN 212 0.0003

GLN 212 ALA 213 -0.0005

ALA 213 THR 214 0.0003

THR 214 ASP 215 0.0000

ASP 215 LYS 216 -0.0002

LYS 216 ARG 217 -0.0001

ARG 217 ASN 218 0.0003

ASN 218 VAL 219 -0.0002

VAL 219 GLU 220 0.0002

GLU 220 PHE 221 -0.0000

PHE 221 LEU 222 -0.0001

LEU 222 ASP 223 -0.0003

ASP 223 VAL 224 0.0001

VAL 224 LEU 225 -0.0002

LEU 225 ILE 226 0.0197

ILE 226 GLU 227 -0.0001

GLU 227 ASN 228 0.0001

ASN 228 GLU 229 0.0000

GLU 229 GLN 230 0.0000

GLN 230 LYS 231 0.0001

LYS 231 GLU 232 -0.0003

GLU 232 VAL 233 -0.0001

VAL 233 ILE 234 -0.0003

ILE 234 ALA 235 -0.0004

ALA 235 HIS 236 -0.0003

HIS 236 THR 237 0.0002

THR 237 VAL 238 -0.0001

VAL 238 VAL 239 0.0002

VAL 239 GLN 240 -0.0002

GLN 240 ARG 241 0.0191

ARG 241 TYR 242 0.0002

TYR 242 LEU 243 -0.0002

LEU 243 GLN 244 0.0002

GLN 244 GLU 245 0.0004

GLU 245 LEU 246 -0.0002

LEU 246 TRP 247 0.0001

TRP 247 HIS 248 -0.0002

HIS 248 GLY 249 -0.0002

GLY 249 SER 250 0.0001

SER 250 LEU 251 -0.0002

LEU 251 THR 252 0.0002

THR 252 TRP 253 0.0001

TRP 253 ALA 254 0.0002

ALA 254 SER 255 0.0001

SER 255 TRP 256 -0.0486

TRP 256 LYS 257 0.0001

LYS 257 ILE 258 -0.0000

ILE 258 LEU 259 -0.0000

LEU 259 LEU 260 -0.0003

LEU 260 LEU 261 0.0000

LEU 261 LEU 262 0.0002

LEU 262 VAL 263 -0.0001

VAL 263 ALA 264 0.0001

ALA 264 PHE 265 0.0000

PHE 265 ILE 266 -0.0003

ILE 266 VAL 267 -0.0001

VAL 267 CYS 268 0.0000

CYS 268 PRO 269 0.0003

PRO 269 PRO 270 0.0003

PRO 270 VAL 271 0.0477

VAL 271 TRP 272 -0.0001

TRP 272 ILE 273 0.0003

ILE 273 GLY 274 0.0001

GLY 274 PHE 275 -0.0002

PHE 275 THR 276 0.0003

THR 276 PHE 277 0.0004

PHE 277 PRO 278 -0.0000

PRO 278 MET 279 -0.0000

MET 279 GLY 280 0.0003

GLY 280 HIS 281 -0.0003

HIS 281 LYS 282 0.0004

LYS 282 PHE 283 -0.0001

PHE 283 ASN 284 0.0001

ASN 284 LYS 285 -0.0001

LYS 285 VAL 286 -0.0157

VAL 286 PRO 287 0.0001

PRO 287 ILE 288 0.0003

ILE 288 ILE 289 0.0001

ILE 289 LYS 290 0.0004

LYS 290 PHE 291 0.0000

PHE 291 MET 292 0.0005

MET 292 SER 293 -0.0001

SER 293 TYR 294 -0.0000

TYR 294 LEU 295 -0.0003

LEU 295 THR 296 0.0002

THR 296 SER 297 0.0002

SER 297 HIS 298 -0.0001

HIS 298 ILE 299 0.0001

ILE 299 TYR 300 -0.0003

TYR 300 LEU 301 -0.0712

LEU 301 MET 302 0.0003

MET 302 ILE 303 0.0003

ILE 303 HIS 304 -0.0003

HIS 304 LEU 305 -0.0003

LEU 305 SER 306 0.0002

SER 306 ILE 307 -0.0005

ILE 307 VAL 308 -0.0003

VAL 308 GLY 309 0.0003

GLY 309 ILE 310 -0.0002

ILE 310 THR 311 -0.0001

THR 311 PRO 312 0.0001

PRO 312 ILE 313 -0.0002

ILE 313 TYR 314 0.0001

TYR 314 PRO 315 0.0002

PRO 315 VAL 316 -0.0044

VAL 316 LEU 317 0.0002

LEU 317 ARG 318 -0.0002

ARG 318 LEU 319 -0.0000

LEU 319 SER 320 0.0005

SER 320 LEU 321 -0.0001

LEU 321 VAL 322 0.0002

VAL 322 PRO 323 0.0003

PRO 323 TYR 324 0.0004

TYR 324 TRP 325 -0.0001

TRP 325 TYR 326 0.0000

TYR 326 GLU 327 0.0002

GLU 327 VAL 328 -0.0001

VAL 328 GLY 329 -0.0002

GLY 329 LEU 330 -0.0001

LEU 330 LEU 331 0.0798

LEU 331 ILE 332 0.0002

ILE 332 TRP 333 0.0000

TRP 333 LEU 334 0.0000

LEU 334 SER 335 -0.0001

SER 335 GLY 336 0.0001

GLY 336 LEU 337 -0.0001

LEU 337 LEU 338 -0.0002

LEU 338 LEU 339 0.0004

LEU 339 PHE 340 0.0001

PHE 340 GLU 341 -0.0003

GLU 341 LEU 342 0.0001

LEU 342 THR 343 -0.0001

THR 343 ASN 344 -0.0003

ASN 344 PRO 345 0.0002

PRO 345 SER 346 -0.0045

SER 346 ASP 347 0.0001

ASP 347 LYS 348 -0.0001

LYS 348 SER 349 -0.0004

SER 349 GLY 350 0.0000

GLY 350 LEU 351 0.0001

LEU 351 GLY 352 0.0004

GLY 352 SER 353 -0.0002

SER 353 ILE 354 -0.0003

ILE 354 LYS 355 -0.0003

LYS 355 VAL 356 0.0004

VAL 356 LEU 357 -0.0000

LEU 357 VAL 358 -0.0002

VAL 358 LEU 359 0.0004

LEU 359 LEU 360 0.0003

LEU 360 LEU 361 -0.0436

LEU 361 GLY 362 0.0001

GLY 362 MET 363 0.0003

MET 363 ALA 364 0.0003

ALA 364 GLY 365 0.0002

GLY 365 VAL 366 0.0000

VAL 366 GLY 367 -0.0004

GLY 367 VAL 368 0.0002

VAL 368 HIS 369 -0.0001

HIS 369 VAL 370 -0.0001

VAL 370 SER 371 -0.0001

SER 371 ALA 372 -0.0004

ALA 372 PHE 373 -0.0004

PHE 373 LEU 374 0.0001

LEU 374 PHE 375 0.0002

PHE 375 VAL 376 -0.0698

VAL 376 SER 377 0.0005

SER 377 LYS 378 -0.0006

LYS 378 GLU 379 0.0002

GLU 379 TYR 380 -0.0002

TYR 380 TRP 381 0.0003

TRP 381 PRO 382 -0.0000

PRO 382 THR 383 -0.0001

THR 383 LEU 384 0.0001

LEU 384 VAL 385 -0.0003

VAL 385 TYR 386 -0.0000

TYR 386 CYS 387 0.0000

CYS 387 ARG 388 -0.0003

ARG 388 ASN 389 -0.0000

ASN 389 GLN 390 0.0003

GLN 390 CYS 391 -0.0385

CYS 391 PHE 392 0.0002

PHE 392 ALA 393 -0.0001

ALA 393 LEU 394 -0.0001

LEU 394 ALA 395 -0.0000

ALA 395 PHE 396 -0.0001

PHE 396 LEU 397 -0.0001

LEU 397 LEU 398 -0.0000

LEU 398 ALA 399 -0.0002

ALA 399 CYS 400 0.0001

CYS 400 VAL 401 0.0002

VAL 401 GLN 402 -0.0004

GLN 402 ILE 403 0.0000

ILE 403 LEU 404 -0.0002

LEU 404 ASP 405 -0.0004

ASP 405 PHE 406 0.0683

PHE 406 LEU 407 -0.0004

LEU 407 SER 408 0.0001

SER 408 PHE 409 0.0001

PHE 409 HIS 410 0.0003

HIS 410 HIS 411 0.0000

HIS 411 LEU 412 0.0000

LEU 412 PHE 413 -0.0003

PHE 413 GLY 414 -0.0001

GLY 414 PRO 415 0.0003

PRO 415 TRP 416 -0.0004

TRP 416 ALA 417 -0.0002

ALA 417 ILE 418 -0.0001

ILE 418 ILE 419 -0.0003

ILE 419 ILE 420 0.0001

ILE 420 GLY 421 0.0028

GLY 421 ASP 422 0.0002

ASP 422 LEU 423 0.0002

LEU 423 LEU 424 -0.0000

LEU 424 LYS 425 0.0002

LYS 425 ASP 426 -0.0002

ASP 426 LEU 427 -0.0002

LEU 427 ALA 428 -0.0003

ALA 428 ARG 429 -0.0002

ARG 429 PHE 430 -0.0000

PHE 430 LEU 431 -0.0000

LEU 431 ALA 432 0.0001

ALA 432 VAL 433 0.0002

VAL 433 LEU 434 -0.0001

LEU 434 ALA 435 0.0002

ALA 435 ILE 436 -0.0413

ILE 436 PHE 437 -0.0001

PHE 437 VAL 438 0.0000

VAL 438 PHE 439 -0.0005

PHE 439 GLY 440 0.0001

GLY 440 PHE 441 -0.0005

PHE 441 SER 442 -0.0001

SER 442 MET 443 0.0001

MET 443 HIS 444 -0.0002

HIS 444 ILE 445 -0.0001

ILE 445 VAL 446 0.0001

VAL 446 ALA 447 -0.0002

ALA 447 LEU 448 0.0002

LEU 448 ASN 449 -0.0002

ASN 449 GLN 450 -0.0002

GLN 450 SER 451 0.0015

SER 451 PHE 452 0.0002

PHE 452 ALA 453 -0.0003

ALA 453 ASN 454 0.0002

ASN 454 PHE 455 -0.0001

PHE 455 SER 456 0.0000

SER 456 PRO 457 -0.0002

PRO 457 GLU 458 -0.0003

GLU 458 ASP 459 -0.0000

ASP 459 LEU 460 -0.0000

LEU 460 ARG 461 0.0002

ARG 461 SER 462 0.0000

SER 462 PHE 463 -0.0000

PHE 463 GLU 464 0.0001

GLU 464 LYS 465 -0.0002

LYS 465 LYS 466 0.1486

LYS 466 ASN 467 -0.0000

ASN 467 ARG 468 -0.0002

ARG 468 ASN 469 -0.0001

ASN 469 ARG 470 -0.0001

ARG 470 GLY 471 -0.0001

GLY 471 TYR 472 -0.0002

TYR 472 PHE 473 -0.0001

PHE 473 SER 474 -0.0003

SER 474 ASP 475 -0.0001

ASP 475 VAL 476 -0.0001

VAL 476 ARG 477 -0.0003

ARG 477 MET 478 -0.0003

MET 478 HIS 479 0.0003

HIS 479 PRO 480 0.0003

PRO 480 ILE 481 0.2859

ILE 481 ASN 482 -0.0002

ASN 482 SER 483 -0.0000

SER 483 PHE 484 -0.0000

PHE 484 GLU 485 -0.0000

GLU 485 LEU 486 -0.0000

LEU 486 LEU 487 0.0002

LEU 487 PHE 488 -0.0001

PHE 488 PHE 489 -0.0001

PHE 489 ALA 490 -0.0000

ALA 490 VAL 491 0.0000

VAL 491 PHE 492 0.0001

PHE 492 GLY 493 -0.0001

GLY 493 GLN 494 -0.0004

GLN 494 THR 495 0.0001

THR 495 THR 496 0.0757

THR 496 THR 497 0.0003

THR 497 GLU 498 0.0000

GLU 498 GLN 499 -0.0002

GLN 499 THR 500 -0.0000

THR 500 GLN 501 -0.0002

GLN 501 VAL 502 0.0001

VAL 502 ASP 503 -0.0001

ASP 503 LYS 504 0.0000

LYS 504 ILE 505 0.0001

ILE 505 LYS 506 0.0000

LYS 506 ASN 507 -0.0001

ASN 507 VAL 508 0.0002

VAL 508 ALA 509 0.0000

ALA 509 THR 510 -0.0000

THR 510 PRO 511 -0.1141

PRO 511 THR 512 0.0001

THR 512 GLN 513 0.0002

GLN 513 PRO 514 -0.0002

PRO 514 TYR 515 0.0000

TYR 515 TRP 516 0.0001

TRP 516 VAL 517 0.0002

VAL 517 GLU 518 -0.0000

GLU 518 TYR 519 -0.0002

TYR 519 LEU 520 -0.0004

LEU 520 PHE 521 0.0001

PHE 521 LYS 522 0.0002

LYS 522 ILE 523 0.0003

ILE 523 VAL 524 0.0001

VAL 524 PHE 525 0.0000

PHE 525 GLY 526 -0.2096

GLY 526 ILE 527 0.0001

ILE 527 TYR 528 -0.0001

TYR 528 MET 529 0.0001

MET 529 LEU 530 -0.0000

LEU 530 VAL 531 -0.0001

VAL 531 SER 532 0.0001

SER 532 VAL 533 -0.0001

VAL 533 VAL 534 -0.0003

VAL 534 VAL 535 0.0005

VAL 535 LEU 536 -0.0002

LEU 536 ILE 537 -0.0002

ILE 537 ASN 538 0.0002

ASN 538 LEU 539 0.0000

LEU 539 LEU 540 0.0001

LEU 540 ILE 541 0.0032

ILE 541 ALA 542 0.0001

ALA 542 MET 543 -0.0003

MET 543 MET 544 0.0001

MET 544 SER 545 0.0003

SER 545 ASP 546 0.0001

ASP 546 THR 547 -0.0004

THR 547 TYR 548 0.0002

TYR 548 GLN 549 0.0002

GLN 549 ARG 550 -0.0001

ARG 550 ILE 551 -0.0001

ILE 551 GLN 552 -0.0001

GLN 552 ALA 553 -0.0002

ALA 553 GLN 554 -0.0001

GLN 554 SER 555 -0.0000

SER 555 ASP 556 -0.1863

ASP 556 ILE 557 0.0000

ILE 557 GLU 558 -0.0002

GLU 558 TRP 559 -0.0002

TRP 559 LYS 560 0.0001

LYS 560 PHE 561 -0.0001

PHE 561 GLY 562 0.0003

GLY 562 LEU 563 -0.0001

LEU 563 SER 564 0.0004

SER 564 LYS 565 0.0000

LYS 565 LEU 566 0.0001

LEU 566 ILE 567 0.0001

ILE 567 ARG 568 -0.0001

ARG 568 ASN 569 -0.0000

ASN 569 MET 570 0.0000

MET 570 HIS 571 0.0060

HIS 571 ARG 572 -0.0002

ARG 572 THR 573 0.0003

THR 573 THR 574 -0.0000

THR 574 THR 575 0.0000

THR 575 ALA 576 -0.0002

ALA 576 PRO 577 -0.0001

PRO 577 SER 578 0.0003

SER 578 PRO 579 -0.0007

PRO 579 LEU 580 0.0001

LEU 580 ASN 581 -0.0001

ASN 581 LEU 582 0.0001

LEU 582 VAL 583 0.0000

VAL 583 THR 584 0.0003

THR 584 THR 585 0.0000

THR 585 TRP 586 -0.0584

TRP 586 PHE 587 0.0004

PHE 587 MET 588 0.0001

MET 588 TRP 589 -0.0000

TRP 589 ILE 590 0.0003

ILE 590 VAL 591 -0.0001

VAL 591 GLU 592 0.0004

GLU 592 LYS 593 0.0001

LYS 593 VAL 594 -0.0000

VAL 594 LYS 595 0.0001

LYS 595 ALA 596 -0.0002

ALA 596 ARG 597 0.0004

ARG 597 MET 598 -0.0001

MET 598 LYS 599 -0.0000

LYS 599 LYS 600 0.0000

LYS 600 LYS 601 -0.0710

LYS 601 LYS 602 0.0004

LYS 602 ARG 603 0.0002

ARG 603 PRO 604 -0.0004

PRO 604 SER 605 0.0003

SER 605 LEU 606 -0.0002

LEU 606 VAL 607 0.0000

VAL 607 GLN 608 0.0000

GLN 608 MET 609 -0.0001

MET 609 MET 610 0.0001

MET 610 GLY 611 0.0000

GLY 611 ILE 612 0.0005

ILE 612 ARG 613 0.0002

ARG 613 GLN 614 0.0001

GLN 614 ALA 615 0.0000

ALA 615 SER 616 -0.2448

SER 616 PRO 617 0.0000

PRO 617 ARG 618 0.0000

ARG 618 THR 619 -0.0001

THR 619 LYS 620 -0.0000

LYS 620 ALA 621 -0.0000

ALA 621 GLY 622 -0.0002

GLY 622 ALA 623 0.0001

ALA 623 LYS 624 0.0001

LYS 624 TRP 625 0.0001

TRP 625 LEU 626 0.0002

LEU 626 SER 627 0.0005

SER 627 LYS 628 -0.0001

LYS 628 ILE 629 0.0001

ILE 629 LYS 630 0.0000

LYS 630 LYS 631 -0.0867

LYS 631 ASP 632 -0.0002

ASP 632 SER 633 -0.0001

SER 633 VAL 634 0.0001

VAL 634 ALA 635 0.0000

ALA 635 LEU 636 0.0000

LEU 636 SER 637 -0.0001

SER 637 GLN 638 -0.0002

GLN 638 VAL 639 0.0003

VAL 639 HIS 640 0.0000

HIS 640 LEU 641 -0.0000

LEU 641 SER 642 0.0004

SER 642 PRO 643 0.0002

PRO 643 LEU 644 0.0001

LEU 644 GLY 645 -0.0001

GLY 645 SER 646 -0.2394

SER 646 GLN 647 0.0002

GLN 647 ALA 648 -0.0003

ALA 648 SER 649 -0.0002

SER 649 PHE 650 -0.0000

PHE 650 SER 651 -0.0003

SER 651 GLN 652 -0.0000

GLN 652 ALA 653 -0.0001

ALA 653 ASN 654 -0.0000

ASN 654 GLN 655 0.0001

GLN 655 ASN 656 0.0000

ASN 656 ARG 657 -0.0001

ARG 657 ILE 658 0.0004

ILE 658 GLU 659 -0.0000

GLU 659 ASN 660 -0.0002

ASN 660 VAL 661 0.0483

VAL 661 ALA 662 -0.0002

ALA 662 ASP 663 0.0003

ASP 663 TRP 664 0.0003

TRP 664 GLU 665 -0.0001

GLU 665 ALA 666 -0.0001

ALA 666 ILE 667 0.0001

ILE 667 ALA 668 -0.0002

ALA 668 LYS 669 0.0001

LYS 669 LYS 670 0.0003

LYS 670 TYR 671 -0.0001

TYR 671 ARG 672 0.0003

ARG 672 ALA 673 -0.0002

ALA 673 LEU 674 0.0002

LEU 674 VAL 675 -0.0001

VAL 675 GLY 676 0.1475

GLY 676 ASP 677 0.0001

ASP 677 GLU 678 0.0001

GLU 678 GLU 679 -0.0001

GLU 679 GLY 680 -0.0000

GLY 680 GLY 681 -0.0003

GLY 681 SER 682 -0.0001

SER 682 LEU 683 -0.0001

LEU 683 LYS 684 -0.0004

LYS 684 ASP 685 0.0004

ASP 685 SER 686 0.0000

SER 686 ASP 687 -0.0003

ASP 687 ALA 688 -0.0001

ALA 688 GLU 689 0.0002

GLU 689 SER 690 -0.0003

SER 690 GLY 691 0.0956

GLY 691 SER 692 0.0001

SER 692 GLN 693 -0.0001

GLN 693 GLU 694 0.0002

GLU 694 GLY 695 -0.0000

GLY 695 SER 696 -0.0001

SER 696 GLY 697 -0.0001

GLY 697 GLY 698 0.0003

GLY 698 GLN 699 0.0000

GLN 699 GLN 700 0.0001

GLN 700 PRO 701 -0.0003

PRO 701 PRO 702 0.0004

PRO 702 ALA 703 -0.0004

ALA 703 GLN 704 0.0001

GLN 704 VAL 705 0.0004

VAL 705 GLY 706 0.1621

GLY 706 ARG 707 0.0001

ARG 707 ARG 708 0.0002

ARG 708 ALA 709 -0.0003

ALA 709 ILE 710 0.0002

ILE 710 LYS 711 -0.0001

LYS 711 ALA 712 0.0002

ALA 712 THR 713 0.0000

THR 713 LEU 714 -0.0003

LEU 714 ALA 715 0.0000

ALA 715 ASP 716 -0.0000

ASP 716 THR 717 -0.0002

THR 717 THR 718 0.0003

THR 718 LYS 719 -0.0003

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.

Should you encounter any unexpected behaviour, please let us know. elNémo has been relocated. **Some cleaning from time to time** Sorry for the inconvenience.

*** nompcdar29 ***

CA strain for 2607010241001575878

--- normal mode 92 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* nompcdar29 *