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* dar29 *

CA strain for 2607160252271657563

--- normal mode 100 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
MET 1 SER 2 -0.0002

SER 2 GLN 3 0.0001

GLN 3 PRO 4 0.0001

PRO 4 ARG 5 0.0001

ARG 5 GLY 6 -0.0002

GLY 6 GLY 7 -0.0000

GLY 7 ARG 8 -0.0001

ARG 8 GLY 9 -0.0188

GLY 9 GLY 10 -0.0002

GLY 10 GLY 11 -0.0005

GLY 11 ARG 12 0.0003

ARG 12 GLY 13 -0.0000

GLY 13 GLY 14 0.0001

GLY 14 GLY 15 -0.0003

GLY 15 VAL 16 0.0002

VAL 16 GLY 17 0.0125

GLY 17 ARG 18 -0.0002

ARG 18 LYS 19 0.0003

LYS 19 THR 20 -0.0004

THR 20 PRO 21 0.0002

PRO 21 SER 22 -0.0001

SER 22 SER 23 0.0003

SER 23 LEU 24 -0.0000

LEU 24 THR 25 0.0094

THR 25 GLY 26 0.0000

GLY 26 PRO 27 0.0002

PRO 27 PRO 28 -0.0001

PRO 28 ASP 29 0.0000

ASP 29 GLU 30 -0.0000

GLU 30 SER 31 0.0001

SER 31 ALA 32 -0.0001

ALA 32 THR 33 0.0114

THR 33 PRO 34 -0.0001

PRO 34 SER 35 -0.0000

SER 35 GLU 36 -0.0004

GLU 36 ARG 37 0.0000

ARG 37 ALA 38 -0.0001

ALA 38 THR 39 0.0001

THR 39 PRO 40 0.0002

PRO 40 ALA 41 -0.0039

ALA 41 SER 42 0.0001

SER 42 LYS 43 -0.0003

LYS 43 ALA 44 0.0001

ALA 44 ASP 45 0.0002

ASP 45 SER 46 -0.0001

SER 46 ASP 47 0.0000

ASP 47 PRO 48 0.0001

PRO 48 LYS 49 0.0089

LYS 49 ASP 50 0.0002

ASP 50 ASP 51 -0.0002

ASP 51 SER 52 -0.0001

SER 52 SER 53 0.0001

SER 53 SER 54 0.0002

SER 54 ASN 55 0.0004

ASN 55 GLY 56 0.0002

GLY 56 ASP 57 -0.0928

ASP 57 LYS 58 0.0000

LYS 58 LYS 59 0.0001

LYS 59 ASP 60 0.0001

ASP 60 MET 61 0.0001

MET 61 ASP 62 -0.0000

ASP 62 LEU 63 -0.0003

LEU 63 PHE 64 0.0001

PHE 64 PRO 65 -0.0633

PRO 65 ALA 66 -0.0002

ALA 66 PRO 67 0.0000

PRO 67 LYS 68 -0.0002

LYS 68 PRO 69 0.0000

PRO 69 PRO 70 0.0001

PRO 70 SER 71 0.0003

SER 71 ALA 72 0.0003

ALA 72 GLY 73 0.0348

GLY 73 ALA 74 0.0003

ALA 74 SER 75 -0.0002

SER 75 ILE 76 -0.0000

ILE 76 ARG 77 0.0000

ARG 77 ASP 78 0.0000

ASP 78 THR 79 0.0001

THR 79 ALA 80 0.0000

ALA 80 ASN 81 0.0254

ASN 81 LYS 82 0.0003

LYS 82 VAL 83 0.0001

VAL 83 LEU 84 0.0002

LEU 84 GLY 85 -0.0002

GLY 85 LEU 86 -0.0001

LEU 86 ALA 87 -0.0002

ALA 87 MET 88 -0.0002

MET 88 LYS 89 0.0059

LYS 89 SER 90 0.0000

SER 90 GLU 91 -0.0000

GLU 91 TRP 92 -0.0000

TRP 92 THR 93 0.0003

THR 93 PRO 94 -0.0004

PRO 94 ILE 95 -0.0002

ILE 95 GLU 96 0.0001

GLU 96 ALA 97 -0.0031

ALA 97 GLU 98 -0.0001

GLU 98 LEU 99 0.0003

LEU 99 LYS 100 0.0003

LYS 100 LYS 101 0.0002

LYS 101 LEU 102 0.0002

LEU 102 GLU 103 -0.0001

GLU 103 LYS 104 0.0000

LYS 104 TYR 105 0.0007

TYR 105 VAL 106 0.0002

VAL 106 ALA 107 -0.0001

ALA 107 ASN 108 0.0001

ASN 108 VAL 109 0.0001

VAL 109 GLY 110 0.0001

GLY 110 GLU 111 0.0002

GLU 111 ASP 112 -0.0002

ASP 112 GLY 113 -0.0162

GLY 113 ASN 114 -0.0001

ASN 114 HIS 115 -0.0003

HIS 115 ILE 116 -0.0001

ILE 116 PRO 117 -0.0004

PRO 117 LEU 118 -0.0002

LEU 118 ALA 119 0.0001

ALA 119 GLY 120 -0.0003

GLY 120 VAL 121 -0.0308

VAL 121 HIS 122 -0.0000

HIS 122 ASP 123 0.0001

ASP 123 MET 124 -0.0000

MET 124 ASN 125 -0.0000

ASN 125 LEU 126 -0.0002

LEU 126 MET 127 0.0001

MET 127 GLU 128 -0.0001

GLU 128 ASP 129 0.0062

ASP 129 LYS 130 -0.0001

LYS 130 ARG 131 0.0001

ARG 131 PHE 132 0.0000

PHE 132 VAL 133 0.0001

VAL 133 TYR 134 -0.0000

TYR 134 ASN 135 -0.0003

ASN 135 LEU 136 -0.0002

LEU 136 MET 137 -0.0147

MET 137 VAL 138 -0.0000

VAL 138 VAL 139 0.0000

VAL 139 SER 140 -0.0003

SER 140 LYS 141 -0.0001

LYS 141 ASN 142 0.0000

ASN 142 HIS 143 0.0003

HIS 143 ASN 144 -0.0002

ASN 144 ASN 145 -0.0365

ASN 145 LYS 146 0.0001

LYS 146 PRO 147 -0.0002

PRO 147 ILE 148 0.0001

ILE 148 GLN 149 -0.0001

GLN 149 GLU 150 -0.0003

GLU 150 PHE 151 -0.0001

PHE 151 VAL 152 -0.0003

VAL 152 LEU 153 0.0340

LEU 153 VAL 154 0.0000

VAL 154 SER 155 0.0002

SER 155 PRO 156 -0.0000

PRO 156 ALA 157 -0.0003

ALA 157 PRO 158 -0.0001

PRO 158 VAL 159 0.0002

VAL 159 ASP 160 -0.0002

ASP 160 THR 161 0.0349

THR 161 ALA 162 0.0000

ALA 162 ALA 163 0.0001

ALA 163 LYS 164 0.0002

LYS 164 LEU 165 -0.0005

LEU 165 SER 166 -0.0000

SER 166 ASN 167 0.0003

ASN 167 ILE 168 0.0002

ILE 168 TYR 169 0.0271

TYR 169 ILE 170 -0.0001

ILE 170 VAL 171 0.0000

VAL 171 LEU 172 0.0001

LEU 172 SER 173 -0.0001

SER 173 THR 174 -0.0001

THR 174 LYS 175 0.0002

LYS 175 GLU 176 0.0000

GLU 176 LYS 177 0.1715

LYS 177 GLU 178 -0.0000

GLU 178 ARG 179 0.0002

ARG 179 ALA 180 -0.0002

ALA 180 LYS 181 -0.0003

LYS 181 ASP 182 -0.0002

ASP 182 LEU 183 -0.0002

LEU 183 VAL 184 -0.0002

VAL 184 ALA 185 0.0081

ALA 185 ALA 186 0.0003

ALA 186 GLY 187 -0.0000

GLY 187 LYS 188 -0.0001

LYS 188 GLN 189 0.0001

GLN 189 CYS 190 0.0000

CYS 190 GLU 191 -0.0001

GLU 191 ALA 192 -0.0000

ALA 192 MET 193 0.0042

MET 193 ALA 194 0.0000

ALA 194 THR 195 -0.0004

THR 195 GLU 196 0.0001

GLU 196 LEU 197 -0.0006

LEU 197 LEU 198 -0.0002

LEU 198 ALA 199 -0.0002

ALA 199 LEU 200 0.0000

LEU 200 ALA 201 -0.0164

ALA 201 ALA 202 0.0002

ALA 202 GLY 203 0.0000

GLY 203 SER 204 0.0001

SER 204 ASP 205 -0.0002

ASP 205 SER 206 0.0005

SER 206 ALA 207 0.0003

ALA 207 GLY 208 0.0001

GLY 208 LYS 209 -0.0174

LYS 209 ILE 210 -0.0002

ILE 210 LEU 211 0.0004

LEU 211 GLN 212 0.0001

GLN 212 ALA 213 0.0003

ALA 213 THR 214 -0.0001

THR 214 ASP 215 -0.0002

ASP 215 LYS 216 -0.0002

LYS 216 ARG 217 -0.0074

ARG 217 ASN 218 -0.0001

ASN 218 VAL 219 0.0001

VAL 219 GLU 220 0.0000

GLU 220 PHE 221 0.0004

PHE 221 LEU 222 0.0003

LEU 222 ASP 223 0.0001

ASP 223 VAL 224 0.0001

VAL 224 LEU 225 -0.0173

LEU 225 ILE 226 -0.0002

ILE 226 GLU 227 0.0004

GLU 227 ASN 228 -0.0001

ASN 228 GLU 229 -0.0000

GLU 229 GLN 230 0.0000

GLN 230 LYS 231 0.0001

LYS 231 GLU 232 0.0002

GLU 232 VAL 233 0.0079

VAL 233 ILE 234 -0.0002

ILE 234 ALA 235 0.0003

ALA 235 HIS 236 0.0001

HIS 236 THR 237 -0.0002

THR 237 VAL 238 0.0001

VAL 238 VAL 239 -0.0001

VAL 239 GLN 240 0.0005

GLN 240 ARG 241 0.0285

ARG 241 TYR 242 0.0001

TYR 242 LEU 243 0.0003

LEU 243 GLN 244 0.0001

GLN 244 GLU 245 -0.0004

GLU 245 LEU 246 0.0001

LEU 246 TRP 247 0.0003

TRP 247 HIS 248 0.0002

HIS 248 GLY 249 0.0348

GLY 249 SER 250 -0.0001

SER 250 LEU 251 0.0002

LEU 251 THR 252 -0.0002

THR 252 TRP 253 -0.0001

TRP 253 ALA 254 0.0002

ALA 254 SER 255 0.0001

SER 255 TRP 256 0.0002

TRP 256 LYS 257 -0.0011

LYS 257 ILE 258 -0.0002

ILE 258 LEU 259 -0.0003

LEU 259 LEU 260 -0.0000

LEU 260 LEU 261 -0.0004

LEU 261 LEU 262 -0.0002

LEU 262 VAL 263 -0.0003

VAL 263 ALA 264 -0.0005

ALA 264 PHE 265 0.0005

PHE 265 ILE 266 0.0001

ILE 266 VAL 267 0.0000

VAL 267 CYS 268 -0.0000

CYS 268 PRO 269 -0.0002

PRO 269 PRO 270 0.0002

PRO 270 VAL 271 0.0001

VAL 271 TRP 272 0.0003

TRP 272 ILE 273 0.0031

ILE 273 GLY 274 0.0001

GLY 274 PHE 275 0.0001

PHE 275 THR 276 0.0002

THR 276 PHE 277 -0.0001

PHE 277 PRO 278 -0.0002

PRO 278 MET 279 0.0004

MET 279 GLY 280 -0.0001

GLY 280 HIS 281 -0.0062

HIS 281 LYS 282 0.0000

LYS 282 PHE 283 0.0004

PHE 283 ASN 284 -0.0001

ASN 284 LYS 285 -0.0000

LYS 285 VAL 286 -0.0001

VAL 286 PRO 287 -0.0001

PRO 287 ILE 288 0.0002

ILE 288 ILE 289 -0.0294

ILE 289 LYS 290 -0.0003

LYS 290 PHE 291 0.0001

PHE 291 MET 292 0.0000

MET 292 SER 293 -0.0002

SER 293 TYR 294 -0.0002

TYR 294 LEU 295 -0.0002

LEU 295 THR 296 -0.0001

THR 296 SER 297 -0.0114

SER 297 HIS 298 -0.0000

HIS 298 ILE 299 -0.0001

ILE 299 TYR 300 -0.0000

TYR 300 LEU 301 -0.0001

LEU 301 MET 302 -0.0001

MET 302 ILE 303 0.0001

ILE 303 HIS 304 0.0004

HIS 304 LEU 305 0.0239

LEU 305 SER 306 -0.0001

SER 306 ILE 307 0.0001

ILE 307 VAL 308 0.0002

VAL 308 GLY 309 0.0002

GLY 309 ILE 310 -0.0002

ILE 310 THR 311 0.0000

THR 311 PRO 312 0.0002

PRO 312 ILE 313 -0.0016

ILE 313 TYR 314 0.0000

TYR 314 PRO 315 0.0001

PRO 315 VAL 316 -0.0001

VAL 316 LEU 317 -0.0001

LEU 317 ARG 318 -0.0001

ARG 318 LEU 319 0.0002

LEU 319 SER 320 0.0001

SER 320 LEU 321 -0.0261

LEU 321 VAL 322 -0.0001

VAL 322 PRO 323 0.0001

PRO 323 TYR 324 0.0002

TYR 324 TRP 325 0.0000

TRP 325 TYR 326 -0.0002

TYR 326 GLU 327 -0.0005

GLU 327 VAL 328 -0.0002

VAL 328 GLY 329 -0.0436

GLY 329 LEU 330 0.0001

LEU 330 LEU 331 -0.0001

LEU 331 ILE 332 0.0001

ILE 332 TRP 333 -0.0002

TRP 333 LEU 334 -0.0001

LEU 334 SER 335 -0.0002

SER 335 GLY 336 -0.0003

GLY 336 LEU 337 0.0017

LEU 337 LEU 338 -0.0002

LEU 338 LEU 339 -0.0001

LEU 339 PHE 340 0.0001

PHE 340 GLU 341 0.0002

GLU 341 LEU 342 -0.0002

LEU 342 THR 343 -0.0001

THR 343 ASN 344 -0.0000

ASN 344 PRO 345 -0.0026

PRO 345 SER 346 -0.0000

SER 346 ASP 347 0.0001

ASP 347 LYS 348 -0.0001

LYS 348 SER 349 -0.0002

SER 349 GLY 350 -0.0001

GLY 350 LEU 351 0.0002

LEU 351 GLY 352 -0.0000

GLY 352 SER 353 -0.0281

SER 353 ILE 354 -0.0002

ILE 354 LYS 355 -0.0000

LYS 355 VAL 356 0.0001

VAL 356 LEU 357 -0.0004

LEU 357 VAL 358 -0.0002

VAL 358 LEU 359 0.0001

LEU 359 LEU 360 0.0001

LEU 360 LEU 361 -0.0165

LEU 361 GLY 362 0.0001

GLY 362 MET 363 0.0000

MET 363 ALA 364 -0.0001

ALA 364 GLY 365 -0.0000

GLY 365 VAL 366 0.0002

VAL 366 GLY 367 0.0003

GLY 367 VAL 368 0.0002

VAL 368 HIS 369 -0.0112

HIS 369 VAL 370 0.0003

VAL 370 SER 371 0.0002

SER 371 ALA 372 -0.0001

ALA 372 PHE 373 0.0004

PHE 373 LEU 374 -0.0002

LEU 374 PHE 375 0.0001

PHE 375 VAL 376 0.0001

VAL 376 SER 377 -0.0208

SER 377 LYS 378 0.0000

LYS 378 GLU 379 -0.0001

GLU 379 TYR 380 0.0003

TYR 380 TRP 381 0.0001

TRP 381 PRO 382 0.0002

PRO 382 THR 383 -0.0002

THR 383 LEU 384 -0.0001

LEU 384 VAL 385 -0.0035

VAL 385 TYR 386 0.0003

TYR 386 CYS 387 -0.0003

CYS 387 ARG 388 0.0001

ARG 388 ASN 389 -0.0001

ASN 389 GLN 390 0.0003

GLN 390 CYS 391 -0.0001

CYS 391 PHE 392 0.0001

PHE 392 ALA 393 0.0112

ALA 393 LEU 394 0.0000

LEU 394 ALA 395 -0.0002

ALA 395 PHE 396 0.0000

PHE 396 LEU 397 -0.0000

LEU 397 LEU 398 0.0001

LEU 398 ALA 399 0.0003

ALA 399 CYS 400 -0.0003

CYS 400 VAL 401 -0.0198

VAL 401 GLN 402 0.0000

GLN 402 ILE 403 -0.0000

ILE 403 LEU 404 -0.0000

LEU 404 ASP 405 -0.0000

ASP 405 PHE 406 -0.0001

PHE 406 LEU 407 -0.0003

LEU 407 SER 408 0.0004

SER 408 PHE 409 -0.0751

PHE 409 HIS 410 -0.0003

HIS 410 HIS 411 -0.0002

HIS 411 LEU 412 -0.0001

LEU 412 PHE 413 0.0003

PHE 413 GLY 414 0.0000

GLY 414 PRO 415 -0.0003

PRO 415 TRP 416 -0.0001

TRP 416 ALA 417 0.0406

ALA 417 ILE 418 0.0001

ILE 418 ILE 419 0.0000

ILE 419 ILE 420 -0.0002

ILE 420 GLY 421 -0.0005

GLY 421 ASP 422 0.0001

ASP 422 LEU 423 -0.0002

LEU 423 LEU 424 0.0000

LEU 424 LYS 425 0.1688

LYS 425 ASP 426 -0.0003

ASP 426 LEU 427 0.0003

LEU 427 ALA 428 0.0002

ALA 428 ARG 429 0.0004

ARG 429 PHE 430 0.0002

PHE 430 LEU 431 0.0001

LEU 431 ALA 432 -0.0002

ALA 432 VAL 433 0.1053

VAL 433 LEU 434 0.0003

LEU 434 ALA 435 0.0001

ALA 435 ILE 436 -0.0002

ILE 436 PHE 437 0.0003

PHE 437 VAL 438 -0.0000

VAL 438 PHE 439 0.0001

PHE 439 GLY 440 -0.0001

GLY 440 PHE 441 0.0200

PHE 441 SER 442 0.0001

SER 442 MET 443 -0.0001

MET 443 HIS 444 -0.0001

HIS 444 ILE 445 -0.0002

ILE 445 VAL 446 -0.0000

VAL 446 ALA 447 0.0001

ALA 447 LEU 448 -0.0001

LEU 448 ASN 449 0.0017

ASN 449 GLN 450 0.0001

GLN 450 SER 451 -0.0002

SER 451 PHE 452 0.0002

PHE 452 ALA 453 -0.0003

ALA 453 ASN 454 -0.0001

ASN 454 PHE 455 0.0002

PHE 455 SER 456 -0.0001

SER 456 PRO 457 -0.0235

PRO 457 GLU 458 0.0000

GLU 458 ASP 459 0.0002

ASP 459 LEU 460 -0.0002

LEU 460 ARG 461 0.0001

ARG 461 SER 462 0.0000

SER 462 PHE 463 0.0000

PHE 463 GLU 464 -0.0002

GLU 464 LYS 465 -0.0155

LYS 465 LYS 466 0.0002

LYS 466 ASN 467 0.0001

ASN 467 ARG 468 0.0000

ARG 468 ASN 469 -0.0001

ASN 469 ARG 470 0.0000

ARG 470 GLY 471 0.0002

GLY 471 TYR 472 -0.0003

TYR 472 PHE 473 0.0405

PHE 473 SER 474 0.0002

SER 474 ASP 475 -0.0001

ASP 475 VAL 476 -0.0002

VAL 476 ARG 477 0.0002

ARG 477 MET 478 0.0003

MET 478 HIS 479 0.0000

HIS 479 PRO 480 -0.0001

PRO 480 ILE 481 0.3307

ILE 481 ASN 482 0.0001

ASN 482 SER 483 0.0003

SER 483 PHE 484 0.0000

PHE 484 GLU 485 0.0003

GLU 485 LEU 486 -0.0000

LEU 486 LEU 487 -0.0002

LEU 487 PHE 488 0.0002

PHE 488 PHE 489 0.0750

PHE 489 ALA 490 -0.0001

ALA 490 VAL 491 0.0003

VAL 491 PHE 492 0.0002

PHE 492 GLY 493 0.0000

GLY 493 GLN 494 0.0002

GLN 494 THR 495 0.0003

THR 495 THR 496 0.0001

THR 496 THR 497 -0.1124

THR 497 GLU 498 -0.0000

GLU 498 GLN 499 0.0001

GLN 499 THR 500 0.0001

THR 500 GLN 501 0.0005

GLN 501 VAL 502 -0.0004

VAL 502 ASP 503 0.0002

ASP 503 LYS 504 -0.0001

LYS 504 ILE 505 0.0548

ILE 505 LYS 506 0.0001

LYS 506 ASN 507 0.0003

ASN 507 VAL 508 0.0001

VAL 508 ALA 509 -0.0002

ALA 509 THR 510 0.0002

THR 510 PRO 511 -0.0000

PRO 511 THR 512 -0.0001

THR 512 GLN 513 0.0001

GLN 513 PRO 514 0.0000

PRO 514 TYR 515 -0.0002

TYR 515 TRP 516 -0.0000

TRP 516 VAL 517 -0.0002

VAL 517 GLU 518 -0.0003

GLU 518 TYR 519 -0.0000

TYR 519 LEU 520 0.0004

LEU 520 PHE 521 0.0494

PHE 521 LYS 522 -0.0001

LYS 522 ILE 523 0.0002

ILE 523 VAL 524 -0.0002

VAL 524 PHE 525 -0.0002

PHE 525 GLY 526 -0.0003

GLY 526 ILE 527 0.0000

ILE 527 TYR 528 0.0003

TYR 528 MET 529 -0.0421

MET 529 LEU 530 0.0003

LEU 530 VAL 531 -0.0003

VAL 531 SER 532 0.0000

SER 532 VAL 533 0.0001

VAL 533 VAL 534 -0.0000

VAL 534 VAL 535 -0.0002

VAL 535 LEU 536 -0.0001

LEU 536 ILE 537 -0.0169

ILE 537 ASN 538 0.0003

ASN 538 LEU 539 0.0000

LEU 539 LEU 540 0.0001

LEU 540 ILE 541 -0.0002

ILE 541 ALA 542 0.0001

ALA 542 MET 543 0.0003

MET 543 MET 544 0.0003

MET 544 SER 545 0.0417

SER 545 ASP 546 0.0001

ASP 546 THR 547 -0.0004

THR 547 TYR 548 0.0001

TYR 548 GLN 549 -0.0001

GLN 549 ARG 550 -0.0002

ARG 550 ILE 551 0.0002

ILE 551 GLN 552 -0.0004

GLN 552 ALA 553 -0.0568

ALA 553 GLN 554 0.0003

GLN 554 SER 555 0.0001

SER 555 ASP 556 0.0001

ASP 556 ILE 557 0.0002

ILE 557 GLU 558 -0.0001

GLU 558 TRP 559 0.0000

TRP 559 LYS 560 0.0003

LYS 560 PHE 561 -0.0332

PHE 561 GLY 562 -0.0001

GLY 562 LEU 563 0.0002

LEU 563 SER 564 -0.0000

SER 564 LYS 565 -0.0004

LYS 565 LEU 566 -0.0000

LEU 566 ILE 567 -0.0000

ILE 567 ARG 568 0.0001

ARG 568 ASN 569 -0.0220

ASN 569 MET 570 0.0002

MET 570 HIS 571 0.0001

HIS 571 ARG 572 -0.0000

ARG 572 THR 573 0.0002

THR 573 THR 574 -0.0003

THR 574 THR 575 0.0000

THR 575 ALA 576 -0.0001

ALA 576 PRO 577 0.0052

PRO 577 SER 578 -0.0004

SER 578 PRO 579 0.0003

PRO 579 LEU 580 -0.0000

LEU 580 ASN 581 -0.0000

ASN 581 LEU 582 -0.0000

LEU 582 VAL 583 0.0002

VAL 583 THR 584 -0.0001

THR 584 THR 585 -0.0160

THR 585 TRP 586 0.0001

TRP 586 PHE 587 -0.0001

PHE 587 MET 588 -0.0001

MET 588 TRP 589 -0.0005

TRP 589 ARG 657 -0.0214

ARG 657 ILE 658 0.0001

ILE 658 GLU 659 -0.0003

GLU 659 ASN 660 -0.0002

ASN 660 VAL 661 0.0001

VAL 661 ALA 662 0.0004

ALA 662 ASP 663 -0.0001

ASP 663 TRP 664 0.0003

TRP 664 GLU 665 -0.0299

GLU 665 ALA 666 -0.0002

ALA 666 ILE 667 -0.0001

ILE 667 ALA 668 0.0001

ALA 668 LYS 669 0.0001

LYS 669 LYS 670 0.0003

LYS 670 TYR 671 0.0002

TYR 671 ARG 672 -0.0002

ARG 672 ALA 673 0.1751

ALA 673 LEU 674 0.0001

LEU 674 VAL 675 0.0002

VAL 675 GLY 676 0.0000

GLY 676 ASP 677 0.0002

ASP 677 GLU 678 -0.0001

GLU 678 GLU 679 0.0000

GLU 679 GLY 680 -0.0001

GLY 680 GLY 681 0.0630

GLY 681 SER 682 -0.0001

SER 682 LEU 683 -0.0001

LEU 683 LYS 684 0.0004

LYS 684 ASP 685 0.0004

ASP 685 SER 686 0.0002

SER 686 ASP 687 -0.0001

ASP 687 ALA 688 -0.0000

ALA 688 GLU 689 -0.0063

GLU 689 SER 690 -0.0001

SER 690 GLY 691 -0.0000

GLY 691 SER 692 -0.0002

SER 692 GLN 693 -0.0001

GLN 693 GLU 694 -0.0004

GLU 694 GLY 695 -0.0003

GLY 695 SER 696 -0.0001

SER 696 GLY 697 -0.2683

GLY 697 GLY 698 -0.0005

GLY 698 GLN 699 0.0003

GLN 699 GLN 700 -0.0001

GLN 700 PRO 701 0.0000

PRO 701 PRO 702 -0.0002

PRO 702 ALA 703 -0.0001

ALA 703 GLN 704 0.0000

GLN 704 VAL 705 0.0263

VAL 705 GLY 706 -0.0003

GLY 706 ARG 707 0.0003

ARG 707 ARG 708 -0.0001

ARG 708 ALA 709 -0.0002

ALA 709 ILE 710 -0.0000

ILE 710 LYS 711 0.0004

LYS 711 ALA 712 0.0003

ALA 712 THR 713 0.0436

THR 713 LEU 714 0.0004

LEU 714 ALA 715 -0.0003

ALA 715 ASP 716 -0.0004

ASP 716 THR 717 -0.0003

THR 717 THR 718 0.0001

THR 718 LYS 719 0.0000

LYS 719 MET 1 -0.0075

MET 1 SER 2 -0.0002

SER 2 GLN 3 0.0002

GLN 3 PRO 4 0.0002

PRO 4 ARG 5 0.0001

ARG 5 GLY 6 -0.0002

GLY 6 GLY 7 0.0001

GLY 7 ARG 8 -0.0000

ARG 8 GLY 9 -0.0024

GLY 9 GLY 10 0.0003

GLY 10 GLY 11 0.0004

GLY 11 ARG 12 -0.0001

ARG 12 GLY 13 0.0001

GLY 13 GLY 14 0.0001

GLY 14 GLY 15 -0.0003

GLY 15 VAL 16 0.0001

VAL 16 GLY 17 -0.0924

GLY 17 ARG 18 0.0003

ARG 18 LYS 19 0.0001

LYS 19 THR 20 -0.0003

THR 20 PRO 21 0.0004

PRO 21 SER 22 -0.0003

SER 22 SER 23 0.0001

SER 23 LEU 24 0.0001

LEU 24 THR 25 0.0073

THR 25 GLY 26 -0.0001

GLY 26 PRO 27 -0.0001

PRO 27 PRO 28 -0.0000

PRO 28 ASP 29 0.0001

ASP 29 GLU 30 -0.0002

GLU 30 SER 31 0.0001

SER 31 ALA 32 0.0000

ALA 32 THR 33 0.0144

THR 33 PRO 34 0.0003

PRO 34 SER 35 0.0002

SER 35 GLU 36 -0.0005

GLU 36 ARG 37 -0.0001

ARG 37 ALA 38 -0.0000

ALA 38 THR 39 -0.0000

THR 39 PRO 40 -0.0001

PRO 40 ALA 41 -0.0180

ALA 41 SER 42 0.0004

SER 42 LYS 43 -0.0000

LYS 43 ALA 44 -0.0003

ALA 44 ASP 45 -0.0002

ASP 45 SER 46 0.0002

SER 46 ASP 47 -0.0001

ASP 47 PRO 48 0.0002

PRO 48 LYS 49 -0.0501

LYS 49 ASP 50 0.0001

ASP 50 ASP 51 -0.0000

ASP 51 SER 52 -0.0001

SER 52 SER 53 0.0001

SER 53 SER 54 0.0000

SER 54 ASN 55 0.0003

ASN 55 GLY 56 -0.0002

GLY 56 ASP 57 0.2155

ASP 57 LYS 58 0.0004

LYS 58 LYS 59 -0.0000

LYS 59 ASP 60 -0.0002

ASP 60 MET 61 0.0000

MET 61 ASP 62 -0.0002

ASP 62 LEU 63 -0.0004

LEU 63 PHE 64 -0.0001

PHE 64 PRO 65 0.1259

PRO 65 ALA 66 -0.0001

ALA 66 PRO 67 0.0001

PRO 67 LYS 68 0.0001

LYS 68 PRO 69 -0.0003

PRO 69 PRO 70 0.0003

PRO 70 SER 71 -0.0001

SER 71 ALA 72 0.0003

ALA 72 GLY 73 -0.0736

GLY 73 ALA 74 0.0002

ALA 74 SER 75 -0.0002

SER 75 ILE 76 0.0003

ILE 76 ARG 77 0.0002

ARG 77 ASP 78 -0.0001

ASP 78 THR 79 0.0002

THR 79 ALA 80 0.0002

ALA 80 ASN 81 -0.0049

ASN 81 LYS 82 0.0000

LYS 82 VAL 83 0.0000

VAL 83 LEU 84 0.0005

LEU 84 GLY 85 -0.0000

GLY 85 LEU 86 -0.0001

LEU 86 ALA 87 -0.0003

ALA 87 MET 88 -0.0002

MET 88 LYS 89 0.0100

LYS 89 SER 90 -0.0000

SER 90 GLU 91 0.0000

GLU 91 TRP 92 -0.0004

TRP 92 THR 93 -0.0001

THR 93 PRO 94 -0.0001

PRO 94 ILE 95 0.0000

ILE 95 GLU 96 -0.0000

GLU 96 ALA 97 0.0031

ALA 97 GLU 98 0.0001

GLU 98 LEU 99 0.0002

LEU 99 LYS 100 0.0003

LYS 100 LYS 101 0.0000

LYS 101 LEU 102 0.0001

LEU 102 GLU 103 -0.0002

GLU 103 LYS 104 0.0001

LYS 104 TYR 105 0.0241

TYR 105 VAL 106 -0.0000

VAL 106 ALA 107 -0.0002

ALA 107 ASN 108 0.0003

ASN 108 VAL 109 -0.0003

VAL 109 GLY 110 -0.0001

GLY 110 GLU 111 -0.0001

GLU 111 ASP 112 -0.0002

ASP 112 GLY 113 -0.0680

GLY 113 ASN 114 -0.0002

ASN 114 HIS 115 -0.0000

HIS 115 ILE 116 -0.0002

ILE 116 PRO 117 -0.0000

PRO 117 LEU 118 0.0001

LEU 118 ALA 119 0.0001

ALA 119 GLY 120 -0.0004

GLY 120 VAL 121 -0.0415

VAL 121 HIS 122 -0.0001

HIS 122 ASP 123 -0.0002

ASP 123 MET 124 -0.0003

MET 124 ASN 125 -0.0003

ASN 125 LEU 126 0.0002

LEU 126 MET 127 0.0001

MET 127 GLU 128 -0.0000

GLU 128 ASP 129 -0.0479

ASP 129 LYS 130 -0.0002

LYS 130 ARG 131 -0.0002

ARG 131 PHE 132 0.0004

PHE 132 VAL 133 0.0002

VAL 133 TYR 134 -0.0001

TYR 134 ASN 135 -0.0002

ASN 135 LEU 136 0.0002

LEU 136 MET 137 -0.0133

MET 137 VAL 138 -0.0003

VAL 138 VAL 139 0.0004

VAL 139 SER 140 -0.0003

SER 140 LYS 141 0.0003

LYS 141 ASN 142 0.0003

ASN 142 HIS 143 -0.0002

HIS 143 ASN 144 0.0001

ASN 144 ASN 145 -0.0112

ASN 145 LYS 146 -0.0001

LYS 146 PRO 147 0.0001

PRO 147 ILE 148 0.0000

ILE 148 GLN 149 0.0004

GLN 149 GLU 150 -0.0003

GLU 150 PHE 151 -0.0003

PHE 151 VAL 152 0.0003

VAL 152 LEU 153 0.0031

LEU 153 VAL 154 0.0002

VAL 154 SER 155 -0.0001

SER 155 PRO 156 -0.0001

PRO 156 ALA 157 0.0001

ALA 157 PRO 158 -0.0002

PRO 158 VAL 159 -0.0001

VAL 159 ASP 160 0.0003

ASP 160 THR 161 -0.0221

THR 161 ALA 162 -0.0003

ALA 162 ALA 163 -0.0001

ALA 163 LYS 164 -0.0005

LYS 164 LEU 165 -0.0003

LEU 165 SER 166 -0.0002

SER 166 ASN 167 -0.0000

ASN 167 ILE 168 -0.0002

ILE 168 TYR 169 -0.0910

TYR 169 ILE 170 0.0003

ILE 170 VAL 171 -0.0003

VAL 171 LEU 172 -0.0001

LEU 172 SER 173 -0.0002

SER 173 THR 174 -0.0004

THR 174 LYS 175 -0.0001

LYS 175 GLU 176 0.0001

GLU 176 LYS 177 -0.0833

LYS 177 GLU 178 -0.0001

GLU 178 ARG 179 -0.0004

ARG 179 ALA 180 0.0000

ALA 180 LYS 181 -0.0001

LYS 181 ASP 182 0.0001

ASP 182 LEU 183 0.0001

LEU 183 VAL 184 0.0004

VAL 184 ALA 185 -0.0079

ALA 185 ALA 186 -0.0001

ALA 186 GLY 187 -0.0002

GLY 187 LYS 188 0.0001

LYS 188 GLN 189 0.0002

GLN 189 CYS 190 -0.0001

CYS 190 GLU 191 -0.0001

GLU 191 ALA 192 0.0003

ALA 192 MET 193 -0.0147

MET 193 ALA 194 0.0005

ALA 194 THR 195 -0.0003

THR 195 GLU 196 0.0001

GLU 196 LEU 197 0.0001

LEU 197 LEU 198 0.0001

LEU 198 ALA 199 -0.0001

ALA 199 LEU 200 0.0001

LEU 200 ALA 201 -0.0040

ALA 201 ALA 202 -0.0000

ALA 202 GLY 203 -0.0002

GLY 203 SER 204 0.0001

SER 204 ASP 205 -0.0002

ASP 205 SER 206 -0.0001

SER 206 ALA 207 -0.0003

ALA 207 GLY 208 0.0002

GLY 208 LYS 209 -0.0484

LYS 209 ILE 210 -0.0002

ILE 210 LEU 211 0.0001

LEU 211 GLN 212 -0.0002

GLN 212 ALA 213 -0.0004

ALA 213 THR 214 0.0000

THR 214 ASP 215 0.0001

ASP 215 LYS 216 0.0002

LYS 216 ARG 217 -0.0073

ARG 217 ASN 218 -0.0004

ASN 218 VAL 219 0.0000

VAL 219 GLU 220 0.0004

GLU 220 PHE 221 -0.0004

PHE 221 LEU 222 -0.0004

LEU 222 ASP 223 0.0000

ASP 223 VAL 224 -0.0002

VAL 224 LEU 225 0.0503

LEU 225 ILE 226 0.0001

ILE 226 GLU 227 0.0003

GLU 227 ASN 228 -0.0003

ASN 228 GLU 229 0.0001

GLU 229 GLN 230 -0.0001

GLN 230 LYS 231 -0.0001

LYS 231 GLU 232 -0.0002

GLU 232 VAL 233 -0.0197

VAL 233 ILE 234 -0.0005

ILE 234 ALA 235 0.0002

ALA 235 HIS 236 -0.0002

HIS 236 THR 237 -0.0003

THR 237 VAL 238 0.0003

VAL 238 VAL 239 0.0001

VAL 239 GLN 240 -0.0000

GLN 240 ARG 241 0.0220

ARG 241 TYR 242 -0.0003

TYR 242 LEU 243 -0.0001

LEU 243 GLN 244 -0.0002

GLN 244 GLU 245 0.0001

GLU 245 LEU 246 0.0000

LEU 246 TRP 247 -0.0001

TRP 247 HIS 248 -0.0001

HIS 248 GLY 249 0.1876

GLY 249 SER 250 0.0001

SER 250 LEU 251 0.0004

LEU 251 THR 252 -0.0001

THR 252 TRP 253 0.0000

TRP 253 ALA 254 0.0001

ALA 254 SER 255 -0.0001

SER 255 TRP 256 -0.0004

TRP 256 LYS 257 0.0062

LYS 257 ILE 258 0.0002

ILE 258 LEU 259 0.0003

LEU 259 LEU 260 0.0001

LEU 260 LEU 261 0.0001

LEU 261 LEU 262 -0.0000

LEU 262 VAL 263 -0.0002

VAL 263 ALA 264 -0.0000

ALA 264 PHE 265 -0.0407

PHE 265 ILE 266 0.0000

ILE 266 VAL 267 0.0003

VAL 267 CYS 268 0.0003

CYS 268 PRO 269 -0.0002

PRO 269 PRO 270 0.0001

PRO 270 VAL 271 0.0000

VAL 271 TRP 272 0.0003

TRP 272 ILE 273 0.0175

ILE 273 GLY 274 -0.0001

GLY 274 PHE 275 0.0000

PHE 275 THR 276 -0.0000

THR 276 PHE 277 -0.0002

PHE 277 PRO 278 0.0002

PRO 278 MET 279 -0.0001

MET 279 GLY 280 0.0002

GLY 280 HIS 281 0.0424

HIS 281 LYS 282 0.0003

LYS 282 PHE 283 -0.0001

PHE 283 ASN 284 0.0001

ASN 284 LYS 285 0.0002

LYS 285 VAL 286 0.0003

VAL 286 PRO 287 0.0001

PRO 287 ILE 288 0.0001

ILE 288 ILE 289 -0.0022

ILE 289 LYS 290 -0.0002

LYS 290 PHE 291 -0.0002

PHE 291 MET 292 -0.0004

MET 292 SER 293 -0.0003

SER 293 TYR 294 -0.0003

TYR 294 LEU 295 0.0002

LEU 295 THR 296 0.0003

THR 296 SER 297 -0.0063

SER 297 HIS 298 0.0003

HIS 298 ILE 299 0.0003

ILE 299 TYR 300 0.0001

TYR 300 LEU 301 0.0003

LEU 301 MET 302 0.0002

MET 302 ILE 303 0.0001

ILE 303 HIS 304 -0.0002

HIS 304 LEU 305 -0.0653

LEU 305 SER 306 -0.0001

SER 306 ILE 307 0.0001

ILE 307 VAL 308 0.0001

VAL 308 GLY 309 -0.0003

GLY 309 ILE 310 0.0001

ILE 310 THR 311 -0.0001

THR 311 PRO 312 0.0002

PRO 312 ILE 313 -0.0606

ILE 313 TYR 314 0.0004

TYR 314 PRO 315 -0.0003

PRO 315 VAL 316 -0.0003

VAL 316 LEU 317 -0.0001

LEU 317 ARG 318 -0.0001

ARG 318 LEU 319 0.0001

LEU 319 SER 320 0.0003

SER 320 LEU 321 -0.0288

LEU 321 VAL 322 -0.0001

VAL 322 PRO 323 -0.0002

PRO 323 TYR 324 0.0004

TYR 324 TRP 325 -0.0003

TRP 325 TYR 326 0.0003

TYR 326 GLU 327 0.0003

GLU 327 VAL 328 -0.0001

VAL 328 GLY 329 -0.1322

GLY 329 LEU 330 0.0004

LEU 330 LEU 331 -0.0003

LEU 331 ILE 332 0.0005

ILE 332 TRP 333 -0.0001

TRP 333 LEU 334 0.0003

LEU 334 SER 335 -0.0002

SER 335 GLY 336 0.0003

GLY 336 LEU 337 -0.0113

LEU 337 LEU 338 0.0000

LEU 338 LEU 339 0.0000

LEU 339 PHE 340 0.0003

PHE 340 GLU 341 -0.0000

GLU 341 LEU 342 -0.0000

LEU 342 THR 343 0.0001

THR 343 ASN 344 -0.0002

ASN 344 PRO 345 -0.0471

PRO 345 SER 346 -0.0005

SER 346 ASP 347 0.0003

ASP 347 LYS 348 0.0002

LYS 348 SER 349 0.0000

SER 349 GLY 350 -0.0001

GLY 350 LEU 351 0.0000

LEU 351 GLY 352 -0.0000

GLY 352 SER 353 0.0580

SER 353 ILE 354 0.0002

ILE 354 LYS 355 -0.0001

LYS 355 VAL 356 0.0005

VAL 356 LEU 357 -0.0002

LEU 357 VAL 358 0.0001

VAL 358 LEU 359 -0.0000

LEU 359 LEU 360 -0.0001

LEU 360 LEU 361 0.0366

LEU 361 GLY 362 0.0000

GLY 362 MET 363 0.0002

MET 363 ALA 364 0.0002

ALA 364 GLY 365 -0.0000

GLY 365 VAL 366 0.0001

VAL 366 GLY 367 -0.0002

GLY 367 VAL 368 0.0001

VAL 368 HIS 369 0.0557

HIS 369 VAL 370 0.0001

VAL 370 SER 371 0.0002

SER 371 ALA 372 -0.0003

ALA 372 PHE 373 0.0004

PHE 373 LEU 374 -0.0001

LEU 374 PHE 375 0.0001

PHE 375 VAL 376 -0.0000

VAL 376 SER 377 0.0361

SER 377 LYS 378 -0.0001

LYS 378 GLU 379 -0.0000

GLU 379 TYR 380 0.0004

TYR 380 TRP 381 0.0001

TRP 381 PRO 382 -0.0000

PRO 382 THR 383 -0.0003

THR 383 LEU 384 0.0001

LEU 384 VAL 385 0.0061

VAL 385 TYR 386 -0.0000

TYR 386 CYS 387 -0.0002

CYS 387 ARG 388 0.0001

ARG 388 ASN 389 0.0002

ASN 389 GLN 390 0.0002

GLN 390 CYS 391 0.0003

CYS 391 PHE 392 -0.0000

PHE 392 ALA 393 0.0194

ALA 393 LEU 394 0.0001

LEU 394 ALA 395 0.0002

ALA 395 PHE 396 0.0001

PHE 396 LEU 397 0.0000

LEU 397 LEU 398 0.0000

LEU 398 ALA 399 -0.0002

ALA 399 CYS 400 0.0002

CYS 400 VAL 401 0.0022

VAL 401 GLN 402 -0.0002

GLN 402 ILE 403 0.0000

ILE 403 LEU 404 -0.0000

LEU 404 ASP 405 -0.0003

ASP 405 PHE 406 0.0001

PHE 406 LEU 407 -0.0001

LEU 407 SER 408 -0.0000

SER 408 PHE 409 0.0153

PHE 409 HIS 410 -0.0001

HIS 410 HIS 411 0.0002

HIS 411 LEU 412 -0.0000

LEU 412 PHE 413 0.0001

PHE 413 GLY 414 -0.0001

GLY 414 PRO 415 -0.0001

PRO 415 TRP 416 0.0002

TRP 416 ALA 417 -0.0052

ALA 417 ILE 418 0.0001

ILE 418 ILE 419 -0.0002

ILE 419 ILE 420 -0.0003

ILE 420 GLY 421 -0.0004

GLY 421 ASP 422 0.0001

ASP 422 LEU 423 0.0002

LEU 423 LEU 424 -0.0001

LEU 424 LYS 425 -0.0897

LYS 425 ASP 426 0.0001

ASP 426 LEU 427 -0.0004

LEU 427 ALA 428 -0.0001

ALA 428 ARG 429 0.0001

ARG 429 PHE 430 0.0001

PHE 430 LEU 431 0.0001

LEU 431 ALA 432 -0.0002

ALA 432 VAL 433 -0.0245

VAL 433 LEU 434 -0.0000

LEU 434 ALA 435 0.0003

ALA 435 ILE 436 0.0004

ILE 436 PHE 437 0.0001

PHE 437 VAL 438 0.0001

VAL 438 PHE 439 -0.0002

PHE 439 GLY 440 0.0000

GLY 440 PHE 441 0.0105

PHE 441 SER 442 -0.0001

SER 442 MET 443 -0.0002

MET 443 HIS 444 -0.0001

HIS 444 ILE 445 -0.0002

ILE 445 VAL 446 -0.0003

VAL 446 ALA 447 0.0001

ALA 447 LEU 448 0.0002

LEU 448 ASN 449 0.0269

ASN 449 GLN 450 -0.0003

GLN 450 SER 451 0.0000

SER 451 PHE 452 -0.0002

PHE 452 ALA 453 0.0003

ALA 453 ASN 454 0.0005

ASN 454 PHE 455 -0.0005

PHE 455 SER 456 0.0001

SER 456 PRO 457 -0.0163

PRO 457 GLU 458 -0.0003

GLU 458 ASP 459 0.0005

ASP 459 LEU 460 0.0000

LEU 460 ARG 461 0.0001

ARG 461 SER 462 0.0002

SER 462 PHE 463 0.0002

PHE 463 GLU 464 0.0001

GLU 464 LYS 465 -0.0017

LYS 465 LYS 466 0.0001

LYS 466 ASN 467 0.0000

ASN 467 ARG 468 -0.0001

ARG 468 ASN 469 0.0001

ASN 469 ARG 470 0.0002

ARG 470 GLY 471 -0.0001

GLY 471 TYR 472 -0.0001

TYR 472 PHE 473 0.0079

PHE 473 SER 474 -0.0001

SER 474 ASP 475 0.0000

ASP 475 VAL 476 0.0000

VAL 476 ARG 477 -0.0002

ARG 477 MET 478 -0.0003

MET 478 HIS 479 0.0004

HIS 479 PRO 480 -0.0003

PRO 480 ILE 481 0.0127

ILE 481 ASN 482 0.0000

ASN 482 SER 483 -0.0004

SER 483 PHE 484 -0.0001

PHE 484 GLU 485 -0.0001

GLU 485 LEU 486 0.0003

LEU 486 LEU 487 -0.0003

LEU 487 PHE 488 -0.0001

PHE 488 PHE 489 0.0832

PHE 489 ALA 490 0.0003

ALA 490 VAL 491 0.0001

VAL 491 PHE 492 -0.0001

PHE 492 GLY 493 -0.0000

GLY 493 GLN 494 0.0003

GLN 494 THR 495 -0.0003

THR 495 THR 496 0.0002

THR 496 THR 497 -0.0505

THR 497 GLU 498 0.0001

GLU 498 GLN 499 0.0002

GLN 499 THR 500 -0.0001

THR 500 GLN 501 -0.0003

GLN 501 VAL 502 -0.0001

VAL 502 ASP 503 0.0001

ASP 503 LYS 504 0.0002

LYS 504 ILE 505 -0.0024

ILE 505 LYS 506 0.0000

LYS 506 ASN 507 0.0000

ASN 507 VAL 508 0.0003

VAL 508 ALA 509 0.0002

ALA 509 THR 510 0.0002

THR 510 PRO 511 0.0002

PRO 511 THR 512 -0.0002

THR 512 GLN 513 -0.0318

GLN 513 PRO 514 0.0003

PRO 514 TYR 515 -0.0003

TYR 515 TRP 516 0.0002

TRP 516 VAL 517 -0.0001

VAL 517 GLU 518 -0.0001

GLU 518 TYR 519 -0.0002

TYR 519 LEU 520 -0.0002

LEU 520 PHE 521 0.0054

PHE 521 LYS 522 0.0001

LYS 522 ILE 523 0.0001

ILE 523 VAL 524 0.0003

VAL 524 PHE 525 -0.0002

PHE 525 GLY 526 -0.0001

GLY 526 ILE 527 -0.0001

ILE 527 TYR 528 -0.0000

TYR 528 MET 529 -0.0201

MET 529 LEU 530 0.0003

LEU 530 VAL 531 0.0001

VAL 531 SER 532 0.0001

SER 532 VAL 533 -0.0004

VAL 533 VAL 534 0.0002

VAL 534 VAL 535 0.0004

VAL 535 LEU 536 -0.0000

LEU 536 ILE 537 -0.0180

ILE 537 ASN 538 0.0002

ASN 538 LEU 539 -0.0000

LEU 539 LEU 540 -0.0000

LEU 540 ILE 541 0.0002

ILE 541 ALA 542 -0.0003

ALA 542 MET 543 -0.0002

MET 543 MET 544 -0.0001

MET 544 SER 545 0.0074

SER 545 ASP 546 0.0000

ASP 546 THR 547 0.0001

THR 547 TYR 548 -0.0003

TYR 548 GLN 549 0.0001

GLN 549 ARG 550 -0.0003

ARG 550 ILE 551 -0.0001

ILE 551 GLN 552 0.0001

GLN 552 ALA 553 0.0281

ALA 553 GLN 554 -0.0002

GLN 554 SER 555 0.0000

SER 555 ASP 556 -0.0002

ASP 556 ILE 557 0.0001

ILE 557 GLU 558 0.0003

GLU 558 TRP 559 -0.0003

TRP 559 LYS 560 0.0003

LYS 560 PHE 561 0.0371

PHE 561 GLY 562 -0.0002

GLY 562 LEU 563 0.0000

LEU 563 SER 564 -0.0001

SER 564 LYS 565 0.0000

LYS 565 LEU 566 0.0002

LEU 566 ILE 567 -0.0000

ILE 567 ARG 568 -0.0000

ARG 568 ASN 569 0.0062

ASN 569 MET 570 0.0001

MET 570 HIS 571 -0.0003

HIS 571 ARG 572 0.0000

ARG 572 THR 573 0.0001

THR 573 THR 574 0.0001

THR 574 THR 575 0.0001

THR 575 ALA 576 0.0001

ALA 576 PRO 577 -0.1035

PRO 577 SER 578 0.0002

SER 578 PRO 579 -0.0003

PRO 579 LEU 580 -0.0002

LEU 580 ASN 581 0.0000

ASN 581 LEU 582 -0.0004

LEU 582 VAL 583 -0.0001

VAL 583 THR 584 -0.0001

THR 584 THR 585 0.0555

THR 585 TRP 586 0.0003

TRP 586 PHE 587 -0.0002

PHE 587 MET 588 -0.0001

MET 588 TRP 589 0.0000

TRP 589 ARG 657 0.0122

ARG 657 ILE 658 -0.0001

ILE 658 GLU 659 -0.0004

GLU 659 ASN 660 -0.0001

ASN 660 VAL 661 0.0001

VAL 661 ALA 662 0.0002

ALA 662 ASP 663 -0.0004

ASP 663 TRP 664 0.0002

TRP 664 GLU 665 -0.0071

GLU 665 ALA 666 0.0001

ALA 666 ILE 667 0.0003

ILE 667 ALA 668 0.0002

ALA 668 LYS 669 0.0000

LYS 669 LYS 670 0.0005

LYS 670 TYR 671 0.0003

TYR 671 ARG 672 -0.0001

ARG 672 ALA 673 -0.0718

ALA 673 LEU 674 0.0004

LEU 674 VAL 675 0.0001

VAL 675 GLY 676 0.0002

GLY 676 ASP 677 -0.0002

ASP 677 GLU 678 -0.0000

GLU 678 GLU 679 0.0001

GLU 679 GLY 680 0.0001

GLY 680 GLY 681 -0.0641

GLY 681 SER 682 -0.0001

SER 682 LEU 683 0.0003

LEU 683 LYS 684 0.0002

LYS 684 ASP 685 0.0000

ASP 685 SER 686 0.0002

SER 686 ASP 687 -0.0002

ASP 687 ALA 688 0.0001

ALA 688 GLU 689 -0.1563

GLU 689 SER 690 -0.0001

SER 690 GLY 691 0.0000

GLY 691 SER 692 0.0001

SER 692 GLN 693 -0.0002

GLN 693 GLU 694 -0.0001

GLU 694 GLY 695 0.0000

GLY 695 SER 696 0.0001

SER 696 GLY 697 -0.0142

GLY 697 GLY 698 -0.0003

GLY 698 GLN 699 -0.0000

GLN 699 GLN 700 0.0001

GLN 700 PRO 701 0.0001

PRO 701 PRO 702 0.0001

PRO 702 ALA 703 -0.0000

ALA 703 GLN 704 0.0002

GLN 704 VAL 705 0.0614

VAL 705 GLY 706 0.0000

GLY 706 ARG 707 -0.0005

ARG 707 ARG 708 0.0002

ARG 708 ALA 709 -0.0003

ALA 709 ILE 710 0.0001

ILE 710 LYS 711 -0.0002

LYS 711 ALA 712 -0.0001

ALA 712 THR 713 0.1074

THR 713 LEU 714 0.0000

LEU 714 ALA 715 0.0001

ALA 715 ASP 716 -0.0000

ASP 716 THR 717 0.0002

THR 717 THR 718 0.0002

THR 718 LYS 719 0.0000

LYS 719 MET 1 0.0252

MET 1 SER 2 -0.0001

SER 2 GLN 3 0.0002

GLN 3 PRO 4 -0.0001

PRO 4 ARG 5 0.0001

ARG 5 GLY 6 0.0000

GLY 6 GLY 7 0.0000

GLY 7 ARG 8 0.0001

ARG 8 GLY 9 0.0102

GLY 9 GLY 10 0.0004

GLY 10 GLY 11 -0.0002

GLY 11 ARG 12 -0.0002

ARG 12 GLY 13 -0.0002

GLY 13 GLY 14 0.0003

GLY 14 GLY 15 -0.0003

GLY 15 VAL 16 -0.0002

VAL 16 GLY 17 0.0359

GLY 17 ARG 18 -0.0003

ARG 18 LYS 19 0.0001

LYS 19 THR 20 0.0003

THR 20 PRO 21 -0.0003

PRO 21 SER 22 0.0003

SER 22 SER 23 -0.0001

SER 23 LEU 24 -0.0001

LEU 24 THR 25 0.0037

THR 25 GLY 26 -0.0001

GLY 26 PRO 27 0.0003

PRO 27 PRO 28 0.0003

PRO 28 ASP 29 0.0000

ASP 29 GLU 30 0.0002

GLU 30 SER 31 -0.0002

SER 31 ALA 32 -0.0001

ALA 32 THR 33 0.0043

THR 33 PRO 34 -0.0002

PRO 34 SER 35 0.0001

SER 35 GLU 36 0.0001

GLU 36 ARG 37 -0.0000

ARG 37 ALA 38 -0.0004

ALA 38 THR 39 0.0004

THR 39 PRO 40 -0.0005

PRO 40 ALA 41 0.0363

ALA 41 SER 42 -0.0002

SER 42 LYS 43 0.0002

LYS 43 ALA 44 0.0001

ALA 44 ASP 45 0.0002

ASP 45 SER 46 -0.0004

SER 46 ASP 47 0.0002

ASP 47 PRO 48 -0.0002

PRO 48 LYS 49 0.0406

LYS 49 ASP 50 -0.0004

ASP 50 ASP 51 0.0001

ASP 51 SER 52 -0.0001

SER 52 SER 53 0.0002

SER 53 SER 54 0.0001

SER 54 ASN 55 0.0001

ASN 55 GLY 56 0.0001

GLY 56 ASP 57 -0.0932

ASP 57 LYS 58 -0.0002

LYS 58 LYS 59 0.0000

LYS 59 ASP 60 -0.0002

ASP 60 MET 61 0.0001

MET 61 ASP 62 -0.0002

ASP 62 LEU 63 -0.0000

LEU 63 PHE 64 -0.0004

PHE 64 PRO 65 -0.0325

PRO 65 ALA 66 0.0001

ALA 66 PRO 67 0.0001

PRO 67 LYS 68 -0.0002

LYS 68 PRO 69 0.0001

PRO 69 PRO 70 -0.0004

PRO 70 SER 71 0.0002

SER 71 ALA 72 -0.0000

ALA 72 GLY 73 0.0319

GLY 73 ALA 74 0.0002

ALA 74 SER 75 -0.0005

SER 75 ILE 76 0.0001

ILE 76 ARG 77 -0.0001

ARG 77 ASP 78 -0.0004

ASP 78 THR 79 -0.0000

THR 79 ALA 80 0.0002

ALA 80 ASN 81 0.0176

ASN 81 LYS 82 0.0001

LYS 82 VAL 83 -0.0001

VAL 83 LEU 84 0.0003

LEU 84 GLY 85 0.0003

GLY 85 LEU 86 0.0001

LEU 86 ALA 87 -0.0003

ALA 87 MET 88 -0.0000

MET 88 LYS 89 0.0018

LYS 89 SER 90 0.0001

SER 90 GLU 91 -0.0002

GLU 91 TRP 92 -0.0002

TRP 92 THR 93 -0.0003

THR 93 PRO 94 0.0000

PRO 94 ILE 95 -0.0001

ILE 95 GLU 96 -0.0003

GLU 96 ALA 97 0.0056

ALA 97 GLU 98 -0.0000

GLU 98 LEU 99 -0.0003

LEU 99 LYS 100 0.0000

LYS 100 LYS 101 -0.0003

LYS 101 LEU 102 0.0000

LEU 102 GLU 103 0.0003

GLU 103 LYS 104 0.0002

LYS 104 TYR 105 0.0039

TYR 105 VAL 106 -0.0000

VAL 106 ALA 107 0.0001

ALA 107 ASN 108 -0.0000

ASN 108 VAL 109 -0.0003

VAL 109 GLY 110 -0.0001

GLY 110 GLU 111 -0.0002

GLU 111 ASP 112 -0.0001

ASP 112 GLY 113 -0.0190

GLY 113 ASN 114 0.0002

ASN 114 HIS 115 0.0001

HIS 115 ILE 116 -0.0001

ILE 116 PRO 117 0.0004

PRO 117 LEU 118 -0.0002

LEU 118 ALA 119 -0.0000

ALA 119 GLY 120 -0.0006

GLY 120 VAL 121 -0.0481

VAL 121 HIS 122 -0.0004

HIS 122 ASP 123 0.0002

ASP 123 MET 124 0.0002

MET 124 ASN 125 0.0000

ASN 125 LEU 126 -0.0000

LEU 126 MET 127 0.0000

MET 127 GLU 128 0.0003

GLU 128 ASP 129 0.0106

ASP 129 LYS 130 0.0001

LYS 130 ARG 131 -0.0002

ARG 131 PHE 132 0.0001

PHE 132 VAL 133 -0.0000

VAL 133 TYR 134 -0.0004

TYR 134 ASN 135 0.0002

ASN 135 LEU 136 0.0000

LEU 136 MET 137 -0.0013

MET 137 VAL 138 -0.0002

VAL 138 VAL 139 0.0004

VAL 139 SER 140 -0.0002

SER 140 LYS 141 0.0002

LYS 141 ASN 142 -0.0000

ASN 142 HIS 143 -0.0000

HIS 143 ASN 144 0.0000

ASN 144 ASN 145 0.0024

ASN 145 LYS 146 -0.0005

LYS 146 PRO 147 0.0001

PRO 147 ILE 148 -0.0000

ILE 148 GLN 149 -0.0001

GLN 149 GLU 150 -0.0002

GLU 150 PHE 151 0.0002

PHE 151 VAL 152 0.0001

VAL 152 LEU 153 -0.0185

LEU 153 VAL 154 0.0002

VAL 154 SER 155 -0.0004

SER 155 PRO 156 0.0004

PRO 156 ALA 157 0.0001

ALA 157 PRO 158 -0.0002

PRO 158 VAL 159 0.0002

VAL 159 ASP 160 -0.0001

ASP 160 THR 161 -0.0206

THR 161 ALA 162 -0.0002

ALA 162 ALA 163 0.0002

ALA 163 LYS 164 -0.0002

LYS 164 LEU 165 -0.0003

LEU 165 SER 166 -0.0001

SER 166 ASN 167 -0.0004

ASN 167 ILE 168 0.0002

ILE 168 TYR 169 -0.0608

TYR 169 ILE 170 0.0004

ILE 170 VAL 171 0.0001

VAL 171 LEU 172 0.0000

LEU 172 SER 173 0.0001

SER 173 THR 174 0.0001

THR 174 LYS 175 -0.0002

LYS 175 GLU 176 -0.0001

GLU 176 LYS 177 -0.2211

LYS 177 GLU 178 -0.0003

GLU 178 ARG 179 0.0000

ARG 179 ALA 180 -0.0001

ALA 180 LYS 181 0.0000

LYS 181 ASP 182 0.0002

ASP 182 LEU 183 -0.0003

LEU 183 VAL 184 0.0004

VAL 184 ALA 185 0.0287

ALA 185 ALA 186 -0.0002

ALA 186 GLY 187 0.0001

GLY 187 LYS 188 -0.0005

LYS 188 GLN 189 0.0003

GLN 189 CYS 190 0.0002

CYS 190 GLU 191 -0.0005

GLU 191 ALA 192 -0.0001

ALA 192 MET 193 0.0036

MET 193 ALA 194 -0.0001

ALA 194 THR 195 -0.0003

THR 195 GLU 196 0.0003

GLU 196 LEU 197 0.0000

LEU 197 LEU 198 0.0002

LEU 198 ALA 199 -0.0002

ALA 199 LEU 200 -0.0002

LEU 200 ALA 201 0.0197

ALA 201 ALA 202 -0.0002

ALA 202 GLY 203 -0.0004

GLY 203 SER 204 -0.0000

SER 204 ASP 205 -0.0001

ASP 205 SER 206 0.0001

SER 206 ALA 207 -0.0001

ALA 207 GLY 208 -0.0000

GLY 208 LYS 209 0.0170

LYS 209 ILE 210 -0.0002

ILE 210 LEU 211 0.0003

LEU 211 GLN 212 -0.0002

GLN 212 ALA 213 0.0000

ALA 213 THR 214 0.0001

THR 214 ASP 215 0.0001

ASP 215 LYS 216 0.0001

LYS 216 ARG 217 -0.0090

ARG 217 ASN 218 0.0002

ASN 218 VAL 219 0.0002

VAL 219 GLU 220 0.0001

GLU 220 PHE 221 0.0001

PHE 221 LEU 222 -0.0001

LEU 222 ASP 223 -0.0004

ASP 223 VAL 224 0.0002

VAL 224 LEU 225 0.0233

LEU 225 ILE 226 0.0003

ILE 226 GLU 227 0.0000

GLU 227 ASN 228 0.0004

ASN 228 GLU 229 -0.0003

GLU 229 GLN 230 -0.0003

GLN 230 LYS 231 0.0001

LYS 231 GLU 232 -0.0000

GLU 232 VAL 233 -0.0073

VAL 233 ILE 234 0.0001

ILE 234 ALA 235 0.0003

ALA 235 HIS 236 -0.0005

HIS 236 THR 237 0.0001

THR 237 VAL 238 0.0003

VAL 238 VAL 239 0.0002

VAL 239 GLN 240 -0.0001

GLN 240 ARG 241 -0.0136

ARG 241 TYR 242 -0.0003

TYR 242 LEU 243 -0.0000

LEU 243 GLN 244 0.0003

GLN 244 GLU 245 -0.0002

GLU 245 LEU 246 0.0002

LEU 246 TRP 247 0.0001

TRP 247 HIS 248 -0.0002

HIS 248 GLY 249 -0.0254

GLY 249 SER 250 -0.0004

SER 250 LEU 251 0.0001

LEU 251 THR 252 0.0002

THR 252 TRP 253 0.0001

TRP 253 ALA 254 -0.0002

ALA 254 SER 255 0.0002

SER 255 TRP 256 -0.0000

TRP 256 LYS 257 0.0043

LYS 257 ILE 258 0.0004

ILE 258 LEU 259 -0.0001

LEU 259 LEU 260 0.0002

LEU 260 LEU 261 -0.0003

LEU 261 LEU 262 -0.0002

LEU 262 VAL 263 -0.0000

VAL 263 ALA 264 -0.0002

ALA 264 PHE 265 0.0033

PHE 265 ILE 266 -0.0001

ILE 266 VAL 267 0.0004

VAL 267 CYS 268 -0.0002

CYS 268 PRO 269 -0.0001

PRO 269 PRO 270 0.0000

PRO 270 VAL 271 0.0000

VAL 271 TRP 272 0.0002

TRP 272 ILE 273 -0.0001

ILE 273 GLY 274 0.0001

GLY 274 PHE 275 -0.0001

PHE 275 THR 276 -0.0001

THR 276 PHE 277 0.0005

PHE 277 PRO 278 -0.0004

PRO 278 MET 279 -0.0002

MET 279 GLY 280 -0.0002

GLY 280 HIS 281 0.0082

HIS 281 LYS 282 -0.0000

LYS 282 PHE 283 0.0000

PHE 283 ASN 284 -0.0004

ASN 284 LYS 285 -0.0000

LYS 285 VAL 286 0.0000

VAL 286 PRO 287 -0.0005

PRO 287 ILE 288 0.0001

ILE 288 ILE 289 0.0239

ILE 289 LYS 290 0.0002

LYS 290 PHE 291 -0.0004

PHE 291 MET 292 -0.0000

MET 292 SER 293 0.0000

SER 293 TYR 294 0.0001

TYR 294 LEU 295 0.0004

LEU 295 THR 296 0.0000

THR 296 SER 297 0.0132

SER 297 HIS 298 0.0001

HIS 298 ILE 299 -0.0000

ILE 299 TYR 300 -0.0002

TYR 300 LEU 301 -0.0001

LEU 301 MET 302 -0.0002

MET 302 ILE 303 0.0001

ILE 303 HIS 304 0.0001

HIS 304 LEU 305 -0.0159

LEU 305 SER 306 0.0002

SER 306 ILE 307 0.0001

ILE 307 VAL 308 0.0002

VAL 308 GLY 309 -0.0002

GLY 309 ILE 310 -0.0002

ILE 310 THR 311 0.0002

THR 311 PRO 312 -0.0002

PRO 312 ILE 313 -0.0104

ILE 313 TYR 314 0.0001

TYR 314 PRO 315 0.0002

PRO 315 VAL 316 0.0003

VAL 316 LEU 317 -0.0001

LEU 317 ARG 318 0.0000

ARG 318 LEU 319 -0.0003

LEU 319 SER 320 0.0002

SER 320 LEU 321 -0.0015

LEU 321 VAL 322 -0.0002

VAL 322 PRO 323 -0.0002

PRO 323 TYR 324 -0.0004

TYR 324 TRP 325 0.0002

TRP 325 TYR 326 -0.0002

TYR 326 GLU 327 -0.0002

GLU 327 VAL 328 0.0002

VAL 328 GLY 329 -0.0174

GLY 329 LEU 330 0.0001

LEU 330 LEU 331 -0.0000

LEU 331 ILE 332 0.0003

ILE 332 TRP 333 -0.0000

TRP 333 LEU 334 -0.0000

LEU 334 SER 335 0.0000

SER 335 GLY 336 -0.0000

GLY 336 LEU 337 -0.0135

LEU 337 LEU 338 -0.0000

LEU 338 LEU 339 0.0002

LEU 339 PHE 340 0.0000

PHE 340 GLU 341 -0.0003

GLU 341 LEU 342 0.0001

LEU 342 THR 343 -0.0001

THR 343 ASN 344 -0.0002

ASN 344 PRO 345 0.0081

PRO 345 SER 346 0.0003

SER 346 ASP 347 0.0001

ASP 347 LYS 348 -0.0001

LYS 348 SER 349 0.0002

SER 349 GLY 350 0.0000

GLY 350 LEU 351 0.0001

LEU 351 GLY 352 -0.0002

GLY 352 SER 353 0.0140

SER 353 ILE 354 -0.0005

ILE 354 LYS 355 -0.0001

LYS 355 VAL 356 -0.0002

VAL 356 LEU 357 0.0003

LEU 357 VAL 358 -0.0001

VAL 358 LEU 359 0.0001

LEU 359 LEU 360 0.0001

LEU 360 LEU 361 0.0122

LEU 361 GLY 362 -0.0003

GLY 362 MET 363 0.0001

MET 363 ALA 364 0.0000

ALA 364 GLY 365 -0.0001

GLY 365 VAL 366 0.0000

VAL 366 GLY 367 0.0003

GLY 367 VAL 368 -0.0000

VAL 368 HIS 369 0.0109

HIS 369 VAL 370 0.0000

VAL 370 SER 371 -0.0000

SER 371 ALA 372 -0.0003

ALA 372 PHE 373 -0.0004

PHE 373 LEU 374 0.0001

LEU 374 PHE 375 0.0001

PHE 375 VAL 376 -0.0002

VAL 376 SER 377 0.0122

SER 377 LYS 378 -0.0001

LYS 378 GLU 379 0.0001

GLU 379 TYR 380 -0.0001

TYR 380 TRP 381 0.0002

TRP 381 PRO 382 -0.0002

PRO 382 THR 383 0.0000

THR 383 LEU 384 0.0001

LEU 384 VAL 385 0.0068

VAL 385 TYR 386 -0.0003

TYR 386 CYS 387 0.0001

CYS 387 ARG 388 0.0000

ARG 388 ASN 389 0.0002

ASN 389 GLN 390 0.0002

GLN 390 CYS 391 -0.0003

CYS 391 PHE 392 -0.0000

PHE 392 ALA 393 -0.0064

ALA 393 LEU 394 0.0001

LEU 394 ALA 395 0.0001

ALA 395 PHE 396 0.0001

PHE 396 LEU 397 -0.0001

LEU 397 LEU 398 -0.0002

LEU 398 ALA 399 0.0002

ALA 399 CYS 400 0.0001

CYS 400 VAL 401 0.0088

VAL 401 GLN 402 0.0003

GLN 402 ILE 403 0.0004

ILE 403 LEU 404 0.0001

LEU 404 ASP 405 0.0000

ASP 405 PHE 406 0.0003

PHE 406 LEU 407 0.0001

LEU 407 SER 408 -0.0002

SER 408 PHE 409 0.0555

PHE 409 HIS 410 0.0002

HIS 410 HIS 411 -0.0002

HIS 411 LEU 412 -0.0000

LEU 412 PHE 413 -0.0001

PHE 413 GLY 414 -0.0000

GLY 414 PRO 415 -0.0000

PRO 415 TRP 416 0.0000

TRP 416 ALA 417 -0.0556

ALA 417 ILE 418 -0.0000

ILE 418 ILE 419 0.0003

ILE 419 ILE 420 -0.0001

ILE 420 GLY 421 -0.0001

GLY 421 ASP 422 0.0002

ASP 422 LEU 423 -0.0000

LEU 423 LEU 424 -0.0001

LEU 424 LYS 425 -0.1576

LYS 425 ASP 426 -0.0000

ASP 426 LEU 427 0.0002

LEU 427 ALA 428 -0.0001

ALA 428 ARG 429 -0.0002

ARG 429 PHE 430 0.0000

PHE 430 LEU 431 -0.0003

LEU 431 ALA 432 0.0001

ALA 432 VAL 433 -0.0866

VAL 433 LEU 434 0.0000

LEU 434 ALA 435 0.0000

ALA 435 ILE 436 0.0001

ILE 436 PHE 437 -0.0001

PHE 437 VAL 438 -0.0002

VAL 438 PHE 439 -0.0002

PHE 439 GLY 440 0.0001

GLY 440 PHE 441 -0.0261

PHE 441 SER 442 -0.0001

SER 442 MET 443 0.0001

MET 443 HIS 444 0.0002

HIS 444 ILE 445 -0.0000

ILE 445 VAL 446 -0.0002

VAL 446 ALA 447 0.0002

ALA 447 LEU 448 -0.0002

LEU 448 ASN 449 0.0042

ASN 449 GLN 450 -0.0002

GLN 450 SER 451 -0.0001

SER 451 PHE 452 0.0002

PHE 452 ALA 453 0.0000

ALA 453 ASN 454 -0.0002

ASN 454 PHE 455 0.0002

PHE 455 SER 456 -0.0003

SER 456 PRO 457 0.0105

PRO 457 GLU 458 0.0001

GLU 458 ASP 459 -0.0003

ASP 459 LEU 460 -0.0001

LEU 460 ARG 461 0.0001

ARG 461 SER 462 -0.0001

SER 462 PHE 463 -0.0001

PHE 463 GLU 464 0.0002

GLU 464 LYS 465 0.0291

LYS 465 LYS 466 0.0004

LYS 466 ASN 467 -0.0003

ASN 467 ARG 468 0.0000

ARG 468 ASN 469 0.0001

ASN 469 ARG 470 0.0004

ARG 470 GLY 471 -0.0002

GLY 471 TYR 472 0.0001

TYR 472 PHE 473 -0.0520

PHE 473 SER 474 0.0001

SER 474 ASP 475 -0.0000

ASP 475 VAL 476 0.0002

VAL 476 ARG 477 -0.0002

ARG 477 MET 478 0.0001

MET 478 HIS 479 0.0001

HIS 479 PRO 480 0.0003

PRO 480 ILE 481 -0.4128

ILE 481 ASN 482 0.0001

ASN 482 SER 483 -0.0000

SER 483 PHE 484 -0.0001

PHE 484 GLU 485 0.0001

GLU 485 LEU 486 0.0002

LEU 486 LEU 487 0.0005

LEU 487 PHE 488 0.0001

PHE 488 PHE 489 -0.1212

PHE 489 ALA 490 0.0001

ALA 490 VAL 491 -0.0000

VAL 491 PHE 492 -0.0001

PHE 492 GLY 493 0.0000

GLY 493 GLN 494 -0.0000

GLN 494 THR 495 0.0001

THR 495 THR 496 0.0000

THR 496 THR 497 0.1250

THR 497 GLU 498 0.0001

GLU 498 GLN 499 -0.0001

GLN 499 THR 500 0.0001

THR 500 GLN 501 0.0000

GLN 501 VAL 502 -0.0004

VAL 502 ASP 503 -0.0002

ASP 503 LYS 504 -0.0002

LYS 504 ILE 505 -0.0380

ILE 505 LYS 506 -0.0003

LYS 506 ASN 507 -0.0002

ASN 507 VAL 508 -0.0001

VAL 508 ALA 509 -0.0003

ALA 509 THR 510 0.0002

THR 510 PRO 511 -0.0002

PRO 511 THR 512 0.0002

THR 512 GLN 513 0.0176

GLN 513 PRO 514 0.0003

PRO 514 TYR 515 -0.0001

TYR 515 TRP 516 0.0001

TRP 516 VAL 517 0.0005

VAL 517 GLU 518 -0.0000

GLU 518 TYR 519 0.0001

TYR 519 LEU 520 0.0002

LEU 520 PHE 521 -0.0433

PHE 521 LYS 522 0.0000

LYS 522 ILE 523 0.0001

ILE 523 VAL 524 0.0002

VAL 524 PHE 525 0.0001

PHE 525 GLY 526 0.0000

GLY 526 ILE 527 0.0004

ILE 527 TYR 528 -0.0001

TYR 528 MET 529 0.0556

MET 529 LEU 530 0.0002

LEU 530 VAL 531 -0.0000

VAL 531 SER 532 -0.0002

SER 532 VAL 533 -0.0002

VAL 533 VAL 534 -0.0002

VAL 534 VAL 535 -0.0001

VAL 535 LEU 536 -0.0003

LEU 536 ILE 537 0.0281

ILE 537 ASN 538 -0.0001

ASN 538 LEU 539 -0.0002

LEU 539 LEU 540 -0.0002

LEU 540 ILE 541 -0.0001

ILE 541 ALA 542 -0.0004

ALA 542 MET 543 0.0001

MET 543 MET 544 0.0001

MET 544 SER 545 -0.0411

SER 545 ASP 546 0.0000

ASP 546 THR 547 -0.0001

THR 547 TYR 548 -0.0001

TYR 548 GLN 549 -0.0000

GLN 549 ARG 550 0.0000

ARG 550 ILE 551 -0.0003

ILE 551 GLN 552 -0.0001

GLN 552 ALA 553 0.0925

ALA 553 GLN 554 0.0002

GLN 554 SER 555 0.0003

SER 555 ASP 556 0.0003

ASP 556 ILE 557 -0.0000

ILE 557 GLU 558 0.0003

GLU 558 TRP 559 0.0002

TRP 559 LYS 560 0.0002

LYS 560 PHE 561 0.0254

PHE 561 GLY 562 -0.0004

GLY 562 LEU 563 -0.0001

LEU 563 SER 564 -0.0000

SER 564 LYS 565 -0.0001

LYS 565 LEU 566 0.0000

LEU 566 ILE 567 -0.0003

ILE 567 ARG 568 0.0000

ARG 568 ASN 569 -0.0260

ASN 569 MET 570 -0.0001

MET 570 HIS 571 -0.0000

HIS 571 ARG 572 0.0000

ARG 572 THR 573 -0.0001

THR 573 THR 574 0.0004

THR 574 THR 575 -0.0001

THR 575 ALA 576 -0.0001

ALA 576 PRO 577 -0.0268

PRO 577 SER 578 -0.0003

SER 578 PRO 579 0.0004

PRO 579 LEU 580 -0.0001

LEU 580 ASN 581 0.0003

ASN 581 LEU 582 0.0004

LEU 582 VAL 583 -0.0001

VAL 583 THR 584 0.0001

THR 584 THR 585 0.0160

THR 585 TRP 586 0.0001

TRP 586 PHE 587 0.0003

PHE 587 MET 588 -0.0002

MET 588 TRP 589 -0.0002

TRP 589 ARG 657 -0.0381

ARG 657 ILE 658 -0.0000

ILE 658 GLU 659 -0.0001

GLU 659 ASN 660 -0.0001

ASN 660 VAL 661 0.0000

VAL 661 ALA 662 0.0003

ALA 662 ASP 663 0.0001

ASP 663 TRP 664 -0.0000

TRP 664 GLU 665 0.0087

GLU 665 ALA 666 0.0000

ALA 666 ILE 667 0.0002

ILE 667 ALA 668 0.0005

ALA 668 LYS 669 0.0001

LYS 669 LYS 670 -0.0002

LYS 670 TYR 671 0.0001

TYR 671 ARG 672 0.0002

ARG 672 ALA 673 -0.0329

ALA 673 LEU 674 0.0001

LEU 674 VAL 675 0.0004

VAL 675 GLY 676 0.0001

GLY 676 ASP 677 -0.0001

ASP 677 GLU 678 -0.0000

GLU 678 GLU 679 -0.0001

GLU 679 GLY 680 0.0002

GLY 680 GLY 681 0.2179

GLY 681 SER 682 0.0002

SER 682 LEU 683 0.0005

LEU 683 LYS 684 0.0001

LYS 684 ASP 685 0.0001

ASP 685 SER 686 -0.0003

SER 686 ASP 687 0.0002

ASP 687 ALA 688 -0.0002

ALA 688 GLU 689 -0.0573

GLU 689 SER 690 0.0001

SER 690 GLY 691 -0.0002

GLY 691 SER 692 -0.0001

SER 692 GLN 693 -0.0002

GLN 693 GLU 694 0.0003

GLU 694 GLY 695 0.0000

GLY 695 SER 696 0.0000

SER 696 GLY 697 -0.2683

GLY 697 GLY 698 -0.0004

GLY 698 GLN 699 -0.0001

GLN 699 GLN 700 0.0003

GLN 700 PRO 701 -0.0000

PRO 701 PRO 702 0.0001

PRO 702 ALA 703 0.0003

ALA 703 GLN 704 -0.0000

GLN 704 VAL 705 0.0375

VAL 705 GLY 706 0.0002

GLY 706 ARG 707 -0.0000

ARG 707 ARG 708 -0.0001

ARG 708 ALA 709 -0.0001

ALA 709 ILE 710 0.0003

ILE 710 LYS 711 0.0001

LYS 711 ALA 712 -0.0001

ALA 712 THR 713 0.0584

THR 713 LEU 714 -0.0002

LEU 714 ALA 715 -0.0001

ALA 715 ASP 716 0.0003

ASP 716 THR 717 0.0001

THR 717 THR 718 -0.0001

THR 718 LYS 719 0.0001

LYS 719 MET 1 -0.0971

MET 1 SER 2 0.0002

SER 2 GLN 3 -0.0002

GLN 3 PRO 4 -0.0000

PRO 4 ARG 5 0.0003

ARG 5 GLY 6 -0.0000

GLY 6 GLY 7 0.0003

GLY 7 ARG 8 -0.0003

ARG 8 GLY 9 -0.0285

GLY 9 GLY 10 0.0001

GLY 10 GLY 11 -0.0001

GLY 11 ARG 12 -0.0002

ARG 12 GLY 13 -0.0001

GLY 13 GLY 14 -0.0001

GLY 14 GLY 15 0.0001

GLY 15 VAL 16 0.0002

VAL 16 GLY 17 -0.2966

GLY 17 ARG 18 -0.0000

ARG 18 LYS 19 0.0001

LYS 19 THR 20 -0.0002

THR 20 PRO 21 0.0001

PRO 21 SER 22 -0.0000

SER 22 SER 23 0.0004

SER 23 LEU 24 0.0001

LEU 24 THR 25 -0.5639

THR 25 GLY 26 -0.0000

GLY 26 PRO 27 0.0000

PRO 27 PRO 28 0.0000

PRO 28 ASP 29 0.0001

ASP 29 GLU 30 -0.0001

GLU 30 SER 31 0.0000

SER 31 ALA 32 0.0001

ALA 32 THR 33 0.4894

THR 33 PRO 34 0.0001

PRO 34 SER 35 0.0001

SER 35 GLU 36 0.0001

GLU 36 ARG 37 0.0000

ARG 37 ALA 38 0.0001

ALA 38 THR 39 0.0001

THR 39 PRO 40 0.0002

PRO 40 ALA 41 0.2270

ALA 41 SER 42 0.0000

SER 42 LYS 43 -0.0001

LYS 43 ALA 44 0.0001

ALA 44 ASP 45 -0.0001

ASP 45 SER 46 0.0001

SER 46 ASP 47 -0.0000

ASP 47 PRO 48 0.0001

PRO 48 LYS 49 0.0550

LYS 49 ASP 50 0.0001

ASP 50 ASP 51 -0.0001

ASP 51 SER 52 0.0000

SER 52 SER 53 -0.0000

SER 53 SER 54 0.0000

SER 54 ASN 55 -0.0003

ASN 55 GLY 56 -0.0001

GLY 56 ASP 57 -0.2597

ASP 57 LYS 58 0.0001

LYS 58 LYS 59 -0.0000

LYS 59 ASP 60 0.0000

ASP 60 MET 61 -0.0000

MET 61 ASP 62 0.0001

ASP 62 LEU 63 -0.0001

LEU 63 PHE 64 -0.0003

PHE 64 PRO 65 -0.2132

PRO 65 ALA 66 0.0000

ALA 66 PRO 67 0.0001

PRO 67 LYS 68 0.0001

LYS 68 PRO 69 -0.0000

PRO 69 PRO 70 0.0001

PRO 70 SER 71 -0.0001

SER 71 ALA 72 0.0002

ALA 72 GLY 73 -0.1983

GLY 73 ALA 74 0.0003

ALA 74 SER 75 -0.0003

SER 75 ILE 76 0.0004

ILE 76 ARG 77 -0.0002

ARG 77 ASP 78 0.0000

ASP 78 THR 79 0.0001

THR 79 ALA 80 0.0001

ALA 80 ASN 81 -0.0408

ASN 81 LYS 82 0.0003

LYS 82 VAL 83 0.0000

VAL 83 LEU 84 0.0001

LEU 84 GLY 85 -0.0002

GLY 85 LEU 86 0.0001

LEU 86 ALA 87 0.0003

ALA 87 MET 88 0.0002

MET 88 LYS 89 -0.0126

LYS 89 SER 90 0.0000

SER 90 GLU 91 0.0004

GLU 91 TRP 92 -0.0000

TRP 92 THR 93 -0.0001

THR 93 PRO 94 -0.0000

PRO 94 ILE 95 -0.0001

ILE 95 GLU 96 -0.0004

GLU 96 ALA 97 0.0181

ALA 97 GLU 98 0.0001

GLU 98 LEU 99 -0.0001

LEU 99 LYS 100 -0.0001

LYS 100 LYS 101 0.0005

LYS 101 LEU 102 -0.0000

LEU 102 GLU 103 -0.0003

GLU 103 LYS 104 -0.0001

LYS 104 TYR 105 0.0060

TYR 105 VAL 106 -0.0003

VAL 106 ALA 107 -0.0000

ALA 107 ASN 108 -0.0002

ASN 108 VAL 109 -0.0002

VAL 109 GLY 110 0.0001

GLY 110 GLU 111 -0.0001

GLU 111 ASP 112 0.0002

ASP 112 GLY 113 0.1180

GLY 113 ASN 114 -0.0002

ASN 114 HIS 115 0.0004

HIS 115 ILE 116 -0.0003

ILE 116 PRO 117 -0.0004

PRO 117 LEU 118 0.0001

LEU 118 ALA 119 -0.0001

ALA 119 GLY 120 0.0002

GLY 120 VAL 121 0.1059

VAL 121 HIS 122 0.0001

HIS 122 ASP 123 -0.0001

ASP 123 MET 124 0.0001

MET 124 ASN 125 0.0002

ASN 125 LEU 126 0.0001

LEU 126 MET 127 0.0001

MET 127 GLU 128 0.0002

GLU 128 ASP 129 0.0548

ASP 129 LYS 130 -0.0002

LYS 130 ARG 131 -0.0003

ARG 131 PHE 132 0.0000

PHE 132 VAL 133 -0.0001

VAL 133 TYR 134 0.0003

TYR 134 ASN 135 -0.0002

ASN 135 LEU 136 0.0001

LEU 136 MET 137 0.0321

MET 137 VAL 138 -0.0003

VAL 138 VAL 139 -0.0001

VAL 139 SER 140 0.0001

SER 140 LYS 141 0.0003

LYS 141 ASN 142 -0.0000

ASN 142 HIS 143 -0.0001

HIS 143 ASN 144 -0.0005

ASN 144 ASN 145 0.0481

ASN 145 LYS 146 -0.0001

LYS 146 PRO 147 -0.0000

PRO 147 ILE 148 0.0000

ILE 148 GLN 149 -0.0000

GLN 149 GLU 150 -0.0000

GLU 150 PHE 151 0.0001

PHE 151 VAL 152 0.0000

VAL 152 LEU 153 -0.0122

LEU 153 VAL 154 -0.0000

VAL 154 SER 155 0.0002

SER 155 PRO 156 -0.0000

PRO 156 ALA 157 0.0000

ALA 157 PRO 158 -0.0000

PRO 158 VAL 159 0.0002

VAL 159 ASP 160 -0.0003

ASP 160 THR 161 0.0201

THR 161 ALA 162 0.0002

ALA 162 ALA 163 -0.0002

ALA 163 LYS 164 -0.0003

LYS 164 LEU 165 -0.0000

LEU 165 SER 166 -0.0002

SER 166 ASN 167 0.0000

ASN 167 ILE 168 0.0000

ILE 168 TYR 169 0.1266

TYR 169 ILE 170 0.0001

ILE 170 VAL 171 -0.0003

VAL 171 LEU 172 -0.0002

LEU 172 SER 173 -0.0001

SER 173 THR 174 -0.0000

THR 174 LYS 175 0.0003

LYS 175 GLU 176 0.0004

GLU 176 LYS 177 0.1125

LYS 177 GLU 178 -0.0000

GLU 178 ARG 179 -0.0003

ARG 179 ALA 180 -0.0001

ALA 180 LYS 181 -0.0002

LYS 181 ASP 182 -0.0000

ASP 182 LEU 183 -0.0001

LEU 183 VAL 184 0.0001

VAL 184 ALA 185 -0.0566

ALA 185 ALA 186 -0.0003

ALA 186 GLY 187 -0.0002

GLY 187 LYS 188 0.0000

LYS 188 GLN 189 0.0001

GLN 189 CYS 190 0.0001

CYS 190 GLU 191 0.0003

GLU 191 ALA 192 0.0003

ALA 192 MET 193 0.0133

MET 193 ALA 194 -0.0001

ALA 194 THR 195 -0.0000

THR 195 GLU 196 0.0001

GLU 196 LEU 197 0.0003

LEU 197 LEU 198 -0.0005

LEU 198 ALA 199 -0.0000

ALA 199 LEU 200 0.0001

LEU 200 ALA 201 -0.0011

ALA 201 ALA 202 -0.0001

ALA 202 GLY 203 0.0001

GLY 203 SER 204 -0.0001

SER 204 ASP 205 0.0002

ASP 205 SER 206 -0.0001

SER 206 ALA 207 0.0002

ALA 207 GLY 208 0.0001

GLY 208 LYS 209 0.0443

LYS 209 ILE 210 -0.0000

ILE 210 LEU 211 -0.0000

LEU 211 GLN 212 0.0003

GLN 212 ALA 213 -0.0000

ALA 213 THR 214 -0.0002

THR 214 ASP 215 0.0000

ASP 215 LYS 216 0.0002

LYS 216 ARG 217 0.0114

ARG 217 ASN 218 0.0002

ASN 218 VAL 219 -0.0002

VAL 219 GLU 220 -0.0003

GLU 220 PHE 221 -0.0001

PHE 221 LEU 222 -0.0003

LEU 222 ASP 223 0.0002

ASP 223 VAL 224 -0.0002

VAL 224 LEU 225 -0.0572

LEU 225 ILE 226 -0.0002

ILE 226 GLU 227 0.0004

GLU 227 ASN 228 0.0001

ASN 228 GLU 229 -0.0001

GLU 229 GLN 230 0.0002

GLN 230 LYS 231 -0.0002

LYS 231 GLU 232 -0.0000

GLU 232 VAL 233 0.0141

VAL 233 ILE 234 -0.0002

ILE 234 ALA 235 -0.0000

ALA 235 HIS 236 -0.0005

HIS 236 THR 237 -0.0000

THR 237 VAL 238 -0.0002

VAL 238 VAL 239 0.0005

VAL 239 GLN 240 0.0001

GLN 240 ARG 241 -0.0379

ARG 241 TYR 242 -0.0001

TYR 242 LEU 243 -0.0002

LEU 243 GLN 244 -0.0002

GLN 244 GLU 245 -0.0001

GLU 245 LEU 246 0.0000

LEU 246 TRP 247 -0.0004

TRP 247 HIS 248 -0.0000

HIS 248 GLY 249 -0.1839

GLY 249 SER 250 -0.0002

SER 250 LEU 251 0.0000

LEU 251 THR 252 -0.0003

THR 252 TRP 253 0.0000

TRP 253 ALA 254 0.0000

ALA 254 SER 255 0.0004

SER 255 TRP 256 -0.0004

TRP 256 LYS 257 -0.0071

LYS 257 ILE 258 0.0000

ILE 258 LEU 259 -0.0001

LEU 259 LEU 260 -0.0001

LEU 260 LEU 261 0.0001

LEU 261 LEU 262 0.0003

LEU 262 VAL 263 0.0001

VAL 263 ALA 264 0.0003

ALA 264 PHE 265 0.0346

PHE 265 ILE 266 0.0001

ILE 266 VAL 267 -0.0002

VAL 267 CYS 268 0.0001

CYS 268 PRO 269 -0.0001

PRO 269 PRO 270 -0.0002

PRO 270 VAL 271 -0.0000

VAL 271 TRP 272 0.0001

TRP 272 ILE 273 -0.0191

ILE 273 GLY 274 -0.0001

GLY 274 PHE 275 0.0000

PHE 275 THR 276 -0.0000

THR 276 PHE 277 0.0000

PHE 277 PRO 278 0.0002

PRO 278 MET 279 -0.0002

MET 279 GLY 280 -0.0000

GLY 280 HIS 281 -0.0450

HIS 281 LYS 282 0.0000

LYS 282 PHE 283 -0.0002

PHE 283 ASN 284 0.0001

ASN 284 LYS 285 0.0002

LYS 285 VAL 286 0.0000

VAL 286 PRO 287 -0.0001

PRO 287 ILE 288 0.0003

ILE 288 ILE 289 0.0008

ILE 289 LYS 290 0.0000

LYS 290 PHE 291 -0.0004

PHE 291 MET 292 0.0000

MET 292 SER 293 0.0001

SER 293 TYR 294 0.0001

TYR 294 LEU 295 0.0001

LEU 295 THR 296 0.0001

THR 296 SER 297 0.0025

SER 297 HIS 298 0.0000

HIS 298 ILE 299 -0.0001

ILE 299 TYR 300 0.0002

TYR 300 LEU 301 -0.0001

LEU 301 MET 302 0.0003

MET 302 ILE 303 0.0000

ILE 303 HIS 304 -0.0000

HIS 304 LEU 305 0.0544

LEU 305 SER 306 0.0001

SER 306 ILE 307 -0.0002

ILE 307 VAL 308 0.0004

VAL 308 GLY 309 -0.0001

GLY 309 ILE 310 0.0003

ILE 310 THR 311 -0.0001

THR 311 PRO 312 -0.0002

PRO 312 ILE 313 0.0687

ILE 313 TYR 314 0.0001

TYR 314 PRO 315 0.0002

PRO 315 VAL 316 0.0002

VAL 316 LEU 317 -0.0004

LEU 317 ARG 318 0.0001

ARG 318 LEU 319 -0.0000

LEU 319 SER 320 0.0003

SER 320 LEU 321 0.0570

LEU 321 VAL 322 0.0002

VAL 322 PRO 323 -0.0001

PRO 323 TYR 324 -0.0003

TYR 324 TRP 325 0.0002

TRP 325 TYR 326 -0.0002

TYR 326 GLU 327 -0.0003

GLU 327 VAL 328 0.0000

VAL 328 GLY 329 0.1852

GLY 329 LEU 330 0.0001

LEU 330 LEU 331 0.0003

LEU 331 ILE 332 -0.0003

ILE 332 TRP 333 0.0001

TRP 333 LEU 334 0.0000

LEU 334 SER 335 -0.0002

SER 335 GLY 336 0.0004

GLY 336 LEU 337 0.0242

LEU 337 LEU 338 -0.0002

LEU 338 LEU 339 0.0003

LEU 339 PHE 340 -0.0001

PHE 340 GLU 341 -0.0004

GLU 341 LEU 342 -0.0001

LEU 342 THR 343 -0.0002

THR 343 ASN 344 -0.0003

ASN 344 PRO 345 0.0356

PRO 345 SER 346 -0.0002

SER 346 ASP 347 0.0002

ASP 347 LYS 348 -0.0001

LYS 348 SER 349 -0.0000

SER 349 GLY 350 -0.0001

GLY 350 LEU 351 -0.0002

LEU 351 GLY 352 -0.0002

GLY 352 SER 353 -0.0408

SER 353 ILE 354 -0.0001

ILE 354 LYS 355 -0.0002

LYS 355 VAL 356 0.0001

VAL 356 LEU 357 0.0000

LEU 357 VAL 358 0.0001

VAL 358 LEU 359 -0.0003

LEU 359 LEU 360 -0.0001

LEU 360 LEU 361 -0.0371

LEU 361 GLY 362 0.0001

GLY 362 MET 363 0.0000

MET 363 ALA 364 0.0003

ALA 364 GLY 365 -0.0004

GLY 365 VAL 366 0.0003

VAL 366 GLY 367 -0.0002

GLY 367 VAL 368 -0.0001

VAL 368 HIS 369 -0.0509

HIS 369 VAL 370 0.0001

VAL 370 SER 371 0.0002

SER 371 ALA 372 0.0000

ALA 372 PHE 373 -0.0001

PHE 373 LEU 374 -0.0001

LEU 374 PHE 375 -0.0000

PHE 375 VAL 376 0.0002

VAL 376 SER 377 -0.0271

SER 377 LYS 378 -0.0003

LYS 378 GLU 379 0.0003

GLU 379 TYR 380 0.0001

TYR 380 TRP 381 -0.0003

TRP 381 PRO 382 -0.0000

PRO 382 THR 383 -0.0000

THR 383 LEU 384 0.0000

LEU 384 VAL 385 -0.0107

VAL 385 TYR 386 0.0003

TYR 386 CYS 387 -0.0000

CYS 387 ARG 388 -0.0000

ARG 388 ASN 389 0.0001

ASN 389 GLN 390 0.0002

GLN 390 CYS 391 0.0003

CYS 391 PHE 392 0.0000

PHE 392 ALA 393 -0.0235

ALA 393 LEU 394 -0.0001

LEU 394 ALA 395 0.0002

ALA 395 PHE 396 0.0002

PHE 396 LEU 397 -0.0001

LEU 397 LEU 398 0.0001

LEU 398 ALA 399 0.0001

ALA 399 CYS 400 -0.0002

CYS 400 VAL 401 0.0108

VAL 401 GLN 402 0.0002

GLN 402 ILE 403 -0.0003

ILE 403 LEU 404 -0.0000

LEU 404 ASP 405 -0.0003

ASP 405 PHE 406 -0.0002

PHE 406 LEU 407 -0.0002

LEU 407 SER 408 0.0001

SER 408 PHE 409 0.0149

PHE 409 HIS 410 -0.0002

HIS 410 HIS 411 0.0000

HIS 411 LEU 412 0.0001

LEU 412 PHE 413 0.0001

PHE 413 GLY 414 -0.0002

GLY 414 PRO 415 0.0002

PRO 415 TRP 416 0.0004

TRP 416 ALA 417 0.0253

ALA 417 ILE 418 -0.0002

ILE 418 ILE 419 -0.0002

ILE 419 ILE 420 0.0002

ILE 420 GLY 421 0.0003

GLY 421 ASP 422 0.0003

ASP 422 LEU 423 0.0005

LEU 423 LEU 424 0.0002

LEU 424 LYS 425 0.0719

LYS 425 ASP 426 -0.0004

ASP 426 LEU 427 0.0001

LEU 427 ALA 428 0.0001

ALA 428 ARG 429 0.0003

ARG 429 PHE 430 -0.0002

PHE 430 LEU 431 0.0001

LEU 431 ALA 432 -0.0003

ALA 432 VAL 433 -0.0011

VAL 433 LEU 434 -0.0003

LEU 434 ALA 435 0.0000

ALA 435 ILE 436 -0.0004

ILE 436 PHE 437 0.0001

PHE 437 VAL 438 -0.0003

VAL 438 PHE 439 0.0004

PHE 439 GLY 440 0.0004

GLY 440 PHE 441 -0.0092

PHE 441 SER 442 -0.0002

SER 442 MET 443 0.0002

MET 443 HIS 444 -0.0001

HIS 444 ILE 445 0.0001

ILE 445 VAL 446 -0.0001

VAL 446 ALA 447 -0.0002

ALA 447 LEU 448 0.0002

LEU 448 ASN 449 -0.0317

ASN 449 GLN 450 -0.0001

GLN 450 SER 451 -0.0003

SER 451 PHE 452 0.0001

PHE 452 ALA 453 0.0003

ALA 453 ASN 454 -0.0003

ASN 454 PHE 455 0.0003

PHE 455 SER 456 0.0002

SER 456 PRO 457 0.0278

PRO 457 GLU 458 -0.0001

GLU 458 ASP 459 -0.0002

ASP 459 LEU 460 0.0001

LEU 460 ARG 461 -0.0002

ARG 461 SER 462 -0.0000

SER 462 PHE 463 -0.0002

PHE 463 GLU 464 -0.0004

GLU 464 LYS 465 -0.0110

LYS 465 LYS 466 -0.0002

LYS 466 ASN 467 -0.0000

ASN 467 ARG 468 -0.0000

ARG 468 ASN 469 -0.0003

ASN 469 ARG 470 0.0001

ARG 470 GLY 471 -0.0000

GLY 471 TYR 472 -0.0002

TYR 472 PHE 473 0.0039

PHE 473 SER 474 -0.0002

SER 474 ASP 475 0.0000

ASP 475 VAL 476 0.0002

VAL 476 ARG 477 0.0001

ARG 477 MET 478 0.0001

MET 478 HIS 479 0.0001

HIS 479 PRO 480 -0.0002

PRO 480 ILE 481 0.0562

ILE 481 ASN 482 0.0001

ASN 482 SER 483 -0.0001

SER 483 PHE 484 0.0003

PHE 484 GLU 485 -0.0002

GLU 485 LEU 486 0.0001

LEU 486 LEU 487 -0.0001

LEU 487 PHE 488 -0.0002

PHE 488 PHE 489 -0.0380

PHE 489 ALA 490 -0.0001

ALA 490 VAL 491 0.0002

VAL 491 PHE 492 0.0002

PHE 492 GLY 493 -0.0001

GLY 493 GLN 494 0.0000

GLN 494 THR 495 -0.0001

THR 495 THR 496 0.0002

THR 496 THR 497 0.0264

THR 497 GLU 498 -0.0002

GLU 498 GLN 499 0.0001

GLN 499 THR 500 -0.0001

THR 500 GLN 501 -0.0000

GLN 501 VAL 502 0.0000

VAL 502 ASP 503 -0.0002

ASP 503 LYS 504 -0.0001

LYS 504 ILE 505 -0.0088

ILE 505 LYS 506 0.0002

LYS 506 ASN 507 0.0002

ASN 507 VAL 508 0.0002

VAL 508 ALA 509 -0.0001

ALA 509 THR 510 0.0000

THR 510 PRO 511 -0.0004

PRO 511 THR 512 0.0005

THR 512 GLN 513 0.0183

GLN 513 PRO 514 -0.0001

PRO 514 TYR 515 -0.0004

TYR 515 TRP 516 0.0002

TRP 516 VAL 517 0.0000

VAL 517 GLU 518 0.0000

GLU 518 TYR 519 0.0000

TYR 519 LEU 520 0.0004

LEU 520 PHE 521 -0.0106

PHE 521 LYS 522 0.0003

LYS 522 ILE 523 0.0003

ILE 523 VAL 524 0.0001

VAL 524 PHE 525 0.0002

PHE 525 GLY 526 -0.0005

GLY 526 ILE 527 0.0001

ILE 527 TYR 528 -0.0003

TYR 528 MET 529 0.0087

MET 529 LEU 530 0.0000

LEU 530 VAL 531 0.0000

VAL 531 SER 532 -0.0003

SER 532 VAL 533 0.0001

VAL 533 VAL 534 -0.0001

VAL 534 VAL 535 0.0004

VAL 535 LEU 536 0.0001

LEU 536 ILE 537 0.0124

ILE 537 ASN 538 -0.0003

ASN 538 LEU 539 0.0002

LEU 539 LEU 540 0.0002

LEU 540 ILE 541 0.0004

ILE 541 ALA 542 -0.0002

ALA 542 MET 543 0.0001

MET 543 MET 544 0.0002

MET 544 SER 545 -0.0099

SER 545 ASP 546 -0.0002

ASP 546 THR 547 0.0000

THR 547 TYR 548 0.0004

TYR 548 GLN 549 0.0002

GLN 549 ARG 550 0.0002

ARG 550 ILE 551 -0.0001

ILE 551 GLN 552 0.0001

GLN 552 ALA 553 -0.0579

ALA 553 GLN 554 -0.0003

GLN 554 SER 555 -0.0002

SER 555 ASP 556 -0.0001

ASP 556 ILE 557 -0.0001

ILE 557 GLU 558 0.0001

GLU 558 TRP 559 -0.0000

TRP 559 LYS 560 0.0002

LYS 560 PHE 561 -0.0295

PHE 561 GLY 562 -0.0002

GLY 562 LEU 563 0.0001

LEU 563 SER 564 -0.0001

SER 564 LYS 565 0.0003

LYS 565 LEU 566 0.0001

LEU 566 ILE 567 0.0003

ILE 567 ARG 568 0.0004

ARG 568 ASN 569 0.0437

ASN 569 MET 570 0.0002

MET 570 HIS 571 0.0001

HIS 571 ARG 572 0.0000

ARG 572 THR 573 -0.0000

THR 573 THR 574 0.0002

THR 574 THR 575 0.0000

THR 575 ALA 576 -0.0002

ALA 576 PRO 577 0.1164

PRO 577 SER 578 -0.0002

SER 578 PRO 579 -0.0001

PRO 579 LEU 580 0.0005

LEU 580 ASN 581 0.0003

ASN 581 LEU 582 -0.0003

LEU 582 VAL 583 0.0001

VAL 583 THR 584 0.0004

THR 584 THR 585 -0.0504

THR 585 TRP 586 -0.0000

TRP 586 PHE 587 0.0000

PHE 587 MET 588 0.0003

MET 588 TRP 589 -0.0002

TRP 589 ARG 657 0.0308

ARG 657 ILE 658 -0.0003

ILE 658 GLU 659 -0.0003

GLU 659 ASN 660 -0.0003

ASN 660 VAL 661 0.0003

VAL 661 ALA 662 -0.0002

ALA 662 ASP 663 0.0004

ASP 663 TRP 664 -0.0003

TRP 664 GLU 665 0.0008

GLU 665 ALA 666 0.0002

ALA 666 ILE 667 0.0001

ILE 667 ALA 668 -0.0000

ALA 668 LYS 669 0.0001

LYS 669 LYS 670 0.0001

LYS 670 TYR 671 0.0004

TYR 671 ARG 672 -0.0001

ARG 672 ALA 673 -0.0105

ALA 673 LEU 674 0.0001

LEU 674 VAL 675 -0.0003

VAL 675 GLY 676 -0.0000

GLY 676 ASP 677 -0.0005

ASP 677 GLU 678 0.0002

GLU 678 GLU 679 -0.0002

GLU 679 GLY 680 0.0004

GLY 680 GLY 681 0.1040

GLY 681 SER 682 0.0000

SER 682 LEU 683 0.0003

LEU 683 LYS 684 -0.0000

LYS 684 ASP 685 0.0001

ASP 685 SER 686 0.0001

SER 686 ASP 687 0.0001

ASP 687 ALA 688 -0.0001

ALA 688 GLU 689 0.1918

GLU 689 SER 690 -0.0001

SER 690 GLY 691 0.0002

GLY 691 SER 692 -0.0002

SER 692 GLN 693 -0.0000

GLN 693 GLU 694 -0.0001

GLU 694 GLY 695 -0.0002

GLY 695 SER 696 -0.0002

SER 696 GLY 697 0.2943

GLY 697 GLY 698 0.0001

GLY 698 GLN 699 0.0000

GLN 699 GLN 700 0.0002

GLN 700 PRO 701 -0.0002

PRO 701 PRO 702 0.0000

PRO 702 ALA 703 -0.0001

ALA 703 GLN 704 0.0002

GLN 704 VAL 705 -0.0600

VAL 705 GLY 706 0.0001

GLY 706 ARG 707 -0.0000

ARG 707 ARG 708 -0.0001

ARG 708 ALA 709 -0.0002

ALA 709 ILE 710 0.0002

ILE 710 LYS 711 0.0001

LYS 711 ALA 712 -0.0001

ALA 712 THR 713 -0.1446

THR 713 LEU 714 0.0002

LEU 714 ALA 715 -0.0004

ALA 715 ASP 716 0.0004

ASP 716 THR 717 -0.0001

THR 717 THR 718 -0.0002

THR 718 LYS 719 -0.0005

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.

Should you encounter any unexpected behaviour, please let us know. elNémo has been relocated. **Some cleaning from time to time** Sorry for the inconvenience.

*** dar29 ***

CA strain for 2607160252271657563

--- normal mode 100 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* dar29 *