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* dar29 *

CA strain for 2607160252271657563

--- normal mode 103 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
MET 1 SER 2 0.0001

SER 2 GLN 3 0.0001

GLN 3 PRO 4 0.0001

PRO 4 ARG 5 0.0003

ARG 5 GLY 6 -0.0001

GLY 6 GLY 7 -0.0000

GLY 7 ARG 8 0.0001

ARG 8 GLY 9 0.0254

GLY 9 GLY 10 0.0001

GLY 10 GLY 11 0.0000

GLY 11 ARG 12 0.0001

ARG 12 GLY 13 0.0002

GLY 13 GLY 14 -0.0003

GLY 14 GLY 15 -0.0004

GLY 15 VAL 16 0.0000

VAL 16 GLY 17 -0.0084

GLY 17 ARG 18 0.0000

ARG 18 LYS 19 0.0004

LYS 19 THR 20 -0.0003

THR 20 PRO 21 0.0002

PRO 21 SER 22 -0.0001

SER 22 SER 23 0.0000

SER 23 LEU 24 0.0002

LEU 24 THR 25 -0.0156

THR 25 GLY 26 -0.0002

GLY 26 PRO 27 -0.0001

PRO 27 PRO 28 0.0004

PRO 28 ASP 29 -0.0004

ASP 29 GLU 30 -0.0000

GLU 30 SER 31 0.0002

SER 31 ALA 32 -0.0003

ALA 32 THR 33 0.0318

THR 33 PRO 34 0.0000

PRO 34 SER 35 -0.0004

SER 35 GLU 36 0.0003

GLU 36 ARG 37 -0.0000

ARG 37 ALA 38 -0.0001

ALA 38 THR 39 -0.0001

THR 39 PRO 40 -0.0001

PRO 40 ALA 41 -0.0701

ALA 41 SER 42 -0.0002

SER 42 LYS 43 -0.0001

LYS 43 ALA 44 -0.0001

ALA 44 ASP 45 0.0001

ASP 45 SER 46 0.0004

SER 46 ASP 47 -0.0003

ASP 47 PRO 48 0.0001

PRO 48 LYS 49 0.0637

LYS 49 ASP 50 0.0001

ASP 50 ASP 51 -0.0001

ASP 51 SER 52 -0.0001

SER 52 SER 53 -0.0002

SER 53 SER 54 0.0000

SER 54 ASN 55 -0.0000

ASN 55 GLY 56 -0.0001

GLY 56 ASP 57 0.3840

ASP 57 LYS 58 0.0001

LYS 58 LYS 59 -0.0001

LYS 59 ASP 60 -0.0001

ASP 60 MET 61 0.0001

MET 61 ASP 62 -0.0001

ASP 62 LEU 63 0.0003

LEU 63 PHE 64 -0.0001

PHE 64 PRO 65 0.2738

PRO 65 ALA 66 -0.0002

ALA 66 PRO 67 -0.0002

PRO 67 LYS 68 0.0004

LYS 68 PRO 69 0.0000

PRO 69 PRO 70 -0.0002

PRO 70 SER 71 -0.0001

SER 71 ALA 72 0.0001

ALA 72 GLY 73 -0.2728

GLY 73 ALA 74 -0.0001

ALA 74 SER 75 -0.0000

SER 75 ILE 76 0.0000

ILE 76 ARG 77 -0.0002

ARG 77 ASP 78 0.0002

ASP 78 THR 79 0.0001

THR 79 ALA 80 0.0000

ALA 80 ASN 81 -0.0187

ASN 81 LYS 82 -0.0004

LYS 82 VAL 83 -0.0003

VAL 83 LEU 84 0.0003

LEU 84 GLY 85 0.0003

GLY 85 LEU 86 -0.0005

LEU 86 ALA 87 -0.0001

ALA 87 MET 88 -0.0001

MET 88 LYS 89 0.0179

LYS 89 SER 90 -0.0001

SER 90 GLU 91 -0.0000

GLU 91 TRP 92 0.0001

TRP 92 THR 93 -0.0003

THR 93 PRO 94 0.0000

PRO 94 ILE 95 -0.0001

ILE 95 GLU 96 0.0000

GLU 96 ALA 97 0.0528

ALA 97 GLU 98 0.0001

GLU 98 LEU 99 0.0002

LEU 99 LYS 100 0.0001

LYS 100 LYS 101 -0.0002

LYS 101 LEU 102 -0.0000

LEU 102 GLU 103 0.0004

GLU 103 LYS 104 -0.0000

LYS 104 TYR 105 0.0172

TYR 105 VAL 106 0.0000

VAL 106 ALA 107 -0.0001

ALA 107 ASN 108 0.0002

ASN 108 VAL 109 -0.0002

VAL 109 GLY 110 -0.0003

GLY 110 GLU 111 -0.0002

GLU 111 ASP 112 -0.0000

ASP 112 GLY 113 -0.1322

GLY 113 ASN 114 0.0002

ASN 114 HIS 115 0.0003

HIS 115 ILE 116 0.0000

ILE 116 PRO 117 0.0000

PRO 117 LEU 118 0.0000

LEU 118 ALA 119 0.0004

ALA 119 GLY 120 0.0002

GLY 120 VAL 121 -0.1595

VAL 121 HIS 122 -0.0003

HIS 122 ASP 123 -0.0001

ASP 123 MET 124 0.0001

MET 124 ASN 125 -0.0001

ASN 125 LEU 126 -0.0003

LEU 126 MET 127 0.0000

MET 127 GLU 128 -0.0000

GLU 128 ASP 129 0.0954

ASP 129 LYS 130 0.0000

LYS 130 ARG 131 0.0001

ARG 131 PHE 132 0.0000

PHE 132 VAL 133 -0.0001

VAL 133 TYR 134 -0.0001

TYR 134 ASN 135 -0.0000

ASN 135 LEU 136 -0.0001

LEU 136 MET 137 -0.0096

MET 137 VAL 138 -0.0000

VAL 138 VAL 139 0.0002

VAL 139 SER 140 -0.0002

SER 140 LYS 141 -0.0002

LYS 141 ASN 142 0.0002

ASN 142 HIS 143 -0.0005

HIS 143 ASN 144 -0.0000

ASN 144 ASN 145 0.0076

ASN 145 LYS 146 0.0003

LYS 146 PRO 147 -0.0001

PRO 147 ILE 148 -0.0001

ILE 148 GLN 149 0.0003

GLN 149 GLU 150 -0.0000

GLU 150 PHE 151 0.0002

PHE 151 VAL 152 -0.0003

VAL 152 LEU 153 -0.0101

LEU 153 VAL 154 0.0002

VAL 154 SER 155 -0.0001

SER 155 PRO 156 -0.0001

PRO 156 ALA 157 -0.0002

ALA 157 PRO 158 -0.0002

PRO 158 VAL 159 0.0004

VAL 159 ASP 160 -0.0002

ASP 160 THR 161 0.0262

THR 161 ALA 162 -0.0000

ALA 162 ALA 163 -0.0001

ALA 163 LYS 164 0.0004

LYS 164 LEU 165 0.0002

LEU 165 SER 166 -0.0000

SER 166 ASN 167 -0.0003

ASN 167 ILE 168 -0.0002

ILE 168 TYR 169 0.0243

TYR 169 ILE 170 0.0002

ILE 170 VAL 171 0.0003

VAL 171 LEU 172 0.0002

LEU 172 SER 173 0.0001

SER 173 THR 174 0.0001

THR 174 LYS 175 -0.0000

LYS 175 GLU 176 0.0001

GLU 176 LYS 177 -0.0225

LYS 177 GLU 178 -0.0001

GLU 178 ARG 179 -0.0002

ARG 179 ALA 180 -0.0001

ALA 180 LYS 181 0.0002

LYS 181 ASP 182 -0.0002

ASP 182 LEU 183 -0.0002

LEU 183 VAL 184 0.0000

VAL 184 ALA 185 -0.0053

ALA 185 ALA 186 -0.0001

ALA 186 GLY 187 -0.0001

GLY 187 LYS 188 -0.0001

LYS 188 GLN 189 -0.0005

GLN 189 CYS 190 -0.0000

CYS 190 GLU 191 0.0001

GLU 191 ALA 192 -0.0003

ALA 192 MET 193 0.0810

MET 193 ALA 194 0.0000

ALA 194 THR 195 0.0004

THR 195 GLU 196 0.0002

GLU 196 LEU 197 -0.0001

LEU 197 LEU 198 0.0004

LEU 198 ALA 199 0.0001

ALA 199 LEU 200 -0.0003

LEU 200 ALA 201 -0.0203

ALA 201 ALA 202 0.0001

ALA 202 GLY 203 0.0002

GLY 203 SER 204 -0.0002

SER 204 ASP 205 0.0001

ASP 205 SER 206 0.0002

SER 206 ALA 207 -0.0000

ALA 207 GLY 208 -0.0003

GLY 208 LYS 209 0.0239

LYS 209 ILE 210 -0.0000

ILE 210 LEU 211 0.0000

LEU 211 GLN 212 0.0002

GLN 212 ALA 213 0.0002

ALA 213 THR 214 -0.0003

THR 214 ASP 215 -0.0000

ASP 215 LYS 216 0.0002

LYS 216 ARG 217 0.0135

ARG 217 ASN 218 -0.0001

ASN 218 VAL 219 -0.0003

VAL 219 GLU 220 0.0002

GLU 220 PHE 221 0.0001

PHE 221 LEU 222 0.0004

LEU 222 ASP 223 0.0001

ASP 223 VAL 224 0.0001

VAL 224 LEU 225 -0.0518

LEU 225 ILE 226 -0.0001

ILE 226 GLU 227 -0.0001

GLU 227 ASN 228 -0.0000

ASN 228 GLU 229 0.0002

GLU 229 GLN 230 -0.0003

GLN 230 LYS 231 0.0004

LYS 231 GLU 232 -0.0003

GLU 232 VAL 233 0.0204

VAL 233 ILE 234 -0.0003

ILE 234 ALA 235 -0.0001

ALA 235 HIS 236 -0.0002

HIS 236 THR 237 0.0000

THR 237 VAL 238 0.0004

VAL 238 VAL 239 0.0003

VAL 239 GLN 240 -0.0000

GLN 240 ARG 241 -0.0019

ARG 241 TYR 242 -0.0001

TYR 242 LEU 243 0.0002

LEU 243 GLN 244 -0.0001

GLN 244 GLU 245 0.0002

GLU 245 LEU 246 -0.0000

LEU 246 TRP 247 0.0000

TRP 247 HIS 248 0.0002

HIS 248 GLY 249 -0.0625

GLY 249 SER 250 -0.0002

SER 250 LEU 251 -0.0000

LEU 251 THR 252 -0.0003

THR 252 TRP 253 -0.0002

TRP 253 ALA 254 0.0001

ALA 254 SER 255 0.0001

SER 255 TRP 256 0.0002

TRP 256 LYS 257 -0.0060

LYS 257 ILE 258 -0.0002

ILE 258 LEU 259 0.0002

LEU 259 LEU 260 -0.0000

LEU 260 LEU 261 -0.0003

LEU 261 LEU 262 0.0001

LEU 262 VAL 263 0.0001

VAL 263 ALA 264 0.0002

ALA 264 PHE 265 0.0173

PHE 265 ILE 266 0.0004

ILE 266 VAL 267 0.0002

VAL 267 CYS 268 0.0002

CYS 268 PRO 269 -0.0001

PRO 269 PRO 270 -0.0002

PRO 270 VAL 271 -0.0005

VAL 271 TRP 272 0.0000

TRP 272 ILE 273 -0.0054

ILE 273 GLY 274 0.0004

GLY 274 PHE 275 -0.0001

PHE 275 THR 276 0.0002

THR 276 PHE 277 0.0000

PHE 277 PRO 278 -0.0001

PRO 278 MET 279 0.0001

MET 279 GLY 280 0.0001

GLY 280 HIS 281 -0.0354

HIS 281 LYS 282 0.0001

LYS 282 PHE 283 0.0000

PHE 283 ASN 284 0.0001

ASN 284 LYS 285 0.0002

LYS 285 VAL 286 0.0001

VAL 286 PRO 287 -0.0001

PRO 287 ILE 288 -0.0001

ILE 288 ILE 289 -0.0335

ILE 289 LYS 290 0.0000

LYS 290 PHE 291 -0.0001

PHE 291 MET 292 0.0001

MET 292 SER 293 -0.0001

SER 293 TYR 294 0.0001

TYR 294 LEU 295 -0.0000

LEU 295 THR 296 0.0001

THR 296 SER 297 -0.0184

SER 297 HIS 298 0.0000

HIS 298 ILE 299 0.0003

ILE 299 TYR 300 -0.0002

TYR 300 LEU 301 0.0001

LEU 301 MET 302 0.0001

MET 302 ILE 303 0.0001

ILE 303 HIS 304 -0.0003

HIS 304 LEU 305 0.0418

LEU 305 SER 306 -0.0001

SER 306 ILE 307 -0.0002

ILE 307 VAL 308 0.0002

VAL 308 GLY 309 0.0001

GLY 309 ILE 310 -0.0000

ILE 310 THR 311 -0.0003

THR 311 PRO 312 0.0003

PRO 312 ILE 313 0.0342

ILE 313 TYR 314 0.0001

TYR 314 PRO 315 -0.0001

PRO 315 VAL 316 0.0001

VAL 316 LEU 317 -0.0004

LEU 317 ARG 318 -0.0002

ARG 318 LEU 319 0.0003

LEU 319 SER 320 0.0000

SER 320 LEU 321 0.0153

LEU 321 VAL 322 0.0002

VAL 322 PRO 323 -0.0005

PRO 323 TYR 324 0.0000

TYR 324 TRP 325 0.0002

TRP 325 TYR 326 0.0001

TYR 326 GLU 327 -0.0001

GLU 327 VAL 328 -0.0001

VAL 328 GLY 329 0.0344

GLY 329 LEU 330 -0.0002

LEU 330 LEU 331 -0.0003

LEU 331 ILE 332 -0.0000

ILE 332 TRP 333 -0.0001

TRP 333 LEU 334 0.0002

LEU 334 SER 335 0.0001

SER 335 GLY 336 -0.0001

GLY 336 LEU 337 0.0120

LEU 337 LEU 338 -0.0002

LEU 338 LEU 339 -0.0001

LEU 339 PHE 340 0.0004

PHE 340 GLU 341 -0.0001

GLU 341 LEU 342 0.0001

LEU 342 THR 343 0.0002

THR 343 ASN 344 -0.0001

ASN 344 PRO 345 0.0043

PRO 345 SER 346 -0.0000

SER 346 ASP 347 0.0002

ASP 347 LYS 348 -0.0000

LYS 348 SER 349 0.0001

SER 349 GLY 350 -0.0001

GLY 350 LEU 351 0.0002

LEU 351 GLY 352 0.0003

GLY 352 SER 353 -0.0157

SER 353 ILE 354 -0.0003

ILE 354 LYS 355 -0.0000

LYS 355 VAL 356 -0.0002

VAL 356 LEU 357 -0.0001

LEU 357 VAL 358 -0.0002

VAL 358 LEU 359 0.0002

LEU 359 LEU 360 0.0004

LEU 360 LEU 361 -0.0229

LEU 361 GLY 362 -0.0001

GLY 362 MET 363 -0.0002

MET 363 ALA 364 0.0001

ALA 364 GLY 365 0.0001

GLY 365 VAL 366 0.0001

VAL 366 GLY 367 0.0002

GLY 367 VAL 368 0.0005

VAL 368 HIS 369 -0.0142

HIS 369 VAL 370 -0.0001

VAL 370 SER 371 0.0002

SER 371 ALA 372 0.0002

ALA 372 PHE 373 0.0003

PHE 373 LEU 374 0.0000

LEU 374 PHE 375 -0.0001

PHE 375 VAL 376 0.0003

VAL 376 SER 377 -0.0149

SER 377 LYS 378 0.0004

LYS 378 GLU 379 -0.0001

GLU 379 TYR 380 0.0004

TYR 380 TRP 381 0.0001

TRP 381 PRO 382 -0.0003

PRO 382 THR 383 -0.0002

THR 383 LEU 384 -0.0001

LEU 384 VAL 385 -0.0108

VAL 385 TYR 386 0.0003

TYR 386 CYS 387 -0.0004

CYS 387 ARG 388 -0.0001

ARG 388 ASN 389 0.0001

ASN 389 GLN 390 -0.0003

GLN 390 CYS 391 -0.0003

CYS 391 PHE 392 0.0002

PHE 392 ALA 393 -0.0139

ALA 393 LEU 394 0.0004

LEU 394 ALA 395 -0.0001

ALA 395 PHE 396 -0.0001

PHE 396 LEU 397 0.0001

LEU 397 LEU 398 0.0002

LEU 398 ALA 399 -0.0000

ALA 399 CYS 400 0.0001

CYS 400 VAL 401 -0.0145

VAL 401 GLN 402 0.0001

GLN 402 ILE 403 -0.0000

ILE 403 LEU 404 0.0002

LEU 404 ASP 405 0.0001

ASP 405 PHE 406 -0.0003

PHE 406 LEU 407 -0.0000

LEU 407 SER 408 0.0002

SER 408 PHE 409 -0.0017

PHE 409 HIS 410 0.0000

HIS 410 HIS 411 0.0001

HIS 411 LEU 412 -0.0002

LEU 412 PHE 413 0.0002

PHE 413 GLY 414 -0.0002

GLY 414 PRO 415 -0.0002

PRO 415 TRP 416 -0.0002

TRP 416 ALA 417 0.0225

ALA 417 ILE 418 -0.0004

ILE 418 ILE 419 0.0002

ILE 419 ILE 420 -0.0001

ILE 420 GLY 421 -0.0001

GLY 421 ASP 422 0.0005

ASP 422 LEU 423 0.0001

LEU 423 LEU 424 0.0001

LEU 424 LYS 425 0.0649

LYS 425 ASP 426 -0.0003

ASP 426 LEU 427 0.0001

LEU 427 ALA 428 -0.0000

ALA 428 ARG 429 -0.0000

ARG 429 PHE 430 -0.0001

PHE 430 LEU 431 -0.0000

LEU 431 ALA 432 -0.0002

ALA 432 VAL 433 0.0349

VAL 433 LEU 434 -0.0001

LEU 434 ALA 435 0.0000

ALA 435 ILE 436 -0.0001

ILE 436 PHE 437 0.0001

PHE 437 VAL 438 0.0001

VAL 438 PHE 439 -0.0000

PHE 439 GLY 440 0.0000

GLY 440 PHE 441 0.0088

PHE 441 SER 442 -0.0001

SER 442 MET 443 0.0002

MET 443 HIS 444 0.0002

HIS 444 ILE 445 -0.0005

ILE 445 VAL 446 0.0003

VAL 446 ALA 447 -0.0001

ALA 447 LEU 448 0.0000

LEU 448 ASN 449 -0.0021

ASN 449 GLN 450 0.0001

GLN 450 SER 451 0.0002

SER 451 PHE 452 0.0002

PHE 452 ALA 453 0.0000

ALA 453 ASN 454 0.0001

ASN 454 PHE 455 0.0002

PHE 455 SER 456 -0.0004

SER 456 PRO 457 -0.0111

PRO 457 GLU 458 -0.0000

GLU 458 ASP 459 -0.0000

ASP 459 LEU 460 0.0002

LEU 460 ARG 461 -0.0003

ARG 461 SER 462 -0.0004

SER 462 PHE 463 0.0003

PHE 463 GLU 464 0.0003

GLU 464 LYS 465 -0.0093

LYS 465 LYS 466 -0.0001

LYS 466 ASN 467 0.0002

ASN 467 ARG 468 0.0003

ARG 468 ASN 469 -0.0001

ASN 469 ARG 470 0.0001

ARG 470 GLY 471 0.0001

GLY 471 TYR 472 -0.0001

TYR 472 PHE 473 0.0139

PHE 473 SER 474 0.0003

SER 474 ASP 475 0.0002

ASP 475 VAL 476 -0.0000

VAL 476 ARG 477 -0.0004

ARG 477 MET 478 -0.0001

MET 478 HIS 479 -0.0000

HIS 479 PRO 480 -0.0002

PRO 480 ILE 481 0.1433

ILE 481 ASN 482 -0.0003

ASN 482 SER 483 0.0002

SER 483 PHE 484 0.0000

PHE 484 GLU 485 0.0001

GLU 485 LEU 486 -0.0001

LEU 486 LEU 487 -0.0001

LEU 487 PHE 488 0.0002

PHE 488 PHE 489 -0.0205

PHE 489 ALA 490 -0.0003

ALA 490 VAL 491 0.0000

VAL 491 PHE 492 -0.0002

PHE 492 GLY 493 0.0001

GLY 493 GLN 494 -0.0001

GLN 494 THR 495 -0.0001

THR 495 THR 496 -0.0001

THR 496 THR 497 -0.0743

THR 497 GLU 498 -0.0000

GLU 498 GLN 499 0.0001

GLN 499 THR 500 0.0001

THR 500 GLN 501 -0.0002

GLN 501 VAL 502 0.0001

VAL 502 ASP 503 -0.0001

ASP 503 LYS 504 0.0002

LYS 504 ILE 505 0.0121

ILE 505 LYS 506 -0.0000

LYS 506 ASN 507 -0.0002

ASN 507 VAL 508 0.0004

VAL 508 ALA 509 -0.0001

ALA 509 THR 510 0.0003

THR 510 PRO 511 -0.0002

PRO 511 THR 512 0.0003

THR 512 GLN 513 -0.0090

GLN 513 PRO 514 0.0001

PRO 514 TYR 515 -0.0000

TYR 515 TRP 516 -0.0001

TRP 516 VAL 517 -0.0005

VAL 517 GLU 518 -0.0003

GLU 518 TYR 519 -0.0006

TYR 519 LEU 520 -0.0003

LEU 520 PHE 521 0.0164

PHE 521 LYS 522 -0.0001

LYS 522 ILE 523 -0.0002

ILE 523 VAL 524 -0.0004

VAL 524 PHE 525 -0.0001

PHE 525 GLY 526 0.0002

GLY 526 ILE 527 -0.0003

ILE 527 TYR 528 0.0003

TYR 528 MET 529 0.0009

MET 529 LEU 530 0.0000

LEU 530 VAL 531 -0.0005

VAL 531 SER 532 0.0003

SER 532 VAL 533 -0.0002

VAL 533 VAL 534 0.0000

VAL 534 VAL 535 -0.0001

VAL 535 LEU 536 0.0001

LEU 536 ILE 537 -0.0281

ILE 537 ASN 538 0.0002

ASN 538 LEU 539 0.0000

LEU 539 LEU 540 0.0001

LEU 540 ILE 541 0.0001

ILE 541 ALA 542 0.0000

ALA 542 MET 543 -0.0002

MET 543 MET 544 0.0003

MET 544 SER 545 0.0139

SER 545 ASP 546 0.0003

ASP 546 THR 547 -0.0000

THR 547 TYR 548 0.0001

TYR 548 GLN 549 -0.0003

GLN 549 ARG 550 0.0001

ARG 550 ILE 551 -0.0002

ILE 551 GLN 552 0.0001

GLN 552 ALA 553 -0.0363

ALA 553 GLN 554 0.0002

GLN 554 SER 555 0.0002

SER 555 ASP 556 0.0002

ASP 556 ILE 557 -0.0001

ILE 557 GLU 558 -0.0001

GLU 558 TRP 559 0.0002

TRP 559 LYS 560 -0.0004

LYS 560 PHE 561 -0.0112

PHE 561 GLY 562 -0.0001

GLY 562 LEU 563 -0.0003

LEU 563 SER 564 -0.0001

SER 564 LYS 565 -0.0001

LYS 565 LEU 566 -0.0001

LEU 566 ILE 567 0.0002

ILE 567 ARG 568 0.0003

ARG 568 ASN 569 0.0331

ASN 569 MET 570 0.0001

MET 570 HIS 571 -0.0002

HIS 571 ARG 572 0.0001

ARG 572 THR 573 -0.0000

THR 573 THR 574 -0.0000

THR 574 THR 575 -0.0004

THR 575 ALA 576 0.0001

ALA 576 PRO 577 0.0682

PRO 577 SER 578 0.0005

SER 578 PRO 579 -0.0002

PRO 579 LEU 580 -0.0001

LEU 580 ASN 581 -0.0004

ASN 581 LEU 582 -0.0002

LEU 582 VAL 583 0.0002

VAL 583 THR 584 -0.0002

THR 584 THR 585 -0.0381

THR 585 TRP 586 0.0001

TRP 586 PHE 587 0.0003

PHE 587 MET 588 -0.0002

MET 588 TRP 589 -0.0001

TRP 589 ARG 657 0.0270

ARG 657 ILE 658 -0.0002

ILE 658 GLU 659 0.0002

GLU 659 ASN 660 0.0002

ASN 660 VAL 661 -0.0000

VAL 661 ALA 662 -0.0003

ALA 662 ASP 663 0.0003

ASP 663 TRP 664 0.0001

TRP 664 GLU 665 -0.0446

GLU 665 ALA 666 -0.0000

ALA 666 ILE 667 -0.0002

ILE 667 ALA 668 -0.0003

ALA 668 LYS 669 0.0001

LYS 669 LYS 670 -0.0001

LYS 670 TYR 671 0.0000

TYR 671 ARG 672 -0.0002

ARG 672 ALA 673 -0.0010

ALA 673 LEU 674 -0.0005

LEU 674 VAL 675 -0.0003

VAL 675 GLY 676 0.0000

GLY 676 ASP 677 0.0001

ASP 677 GLU 678 -0.0003

GLU 678 GLU 679 -0.0001

GLU 679 GLY 680 -0.0001

GLY 680 GLY 681 -0.0963

GLY 681 SER 682 0.0001

SER 682 LEU 683 0.0001

LEU 683 LYS 684 0.0001

LYS 684 ASP 685 -0.0002

ASP 685 SER 686 -0.0001

SER 686 ASP 687 0.0001

ASP 687 ALA 688 0.0001

ALA 688 GLU 689 -0.1003

GLU 689 SER 690 0.0000

SER 690 GLY 691 0.0001

GLY 691 SER 692 -0.0000

SER 692 GLN 693 -0.0002

GLN 693 GLU 694 -0.0000

GLU 694 GLY 695 0.0003

GLY 695 SER 696 -0.0004

SER 696 GLY 697 -0.3261

GLY 697 GLY 698 -0.0002

GLY 698 GLN 699 -0.0001

GLN 699 GLN 700 -0.0005

GLN 700 PRO 701 -0.0000

PRO 701 PRO 702 -0.0002

PRO 702 ALA 703 0.0000

ALA 703 GLN 704 -0.0002

GLN 704 VAL 705 0.0682

VAL 705 GLY 706 -0.0001

GLY 706 ARG 707 -0.0000

ARG 707 ARG 708 -0.0000

ARG 708 ALA 709 -0.0000

ALA 709 ILE 710 0.0001

ILE 710 LYS 711 0.0002

LYS 711 ALA 712 0.0001

ALA 712 THR 713 0.1783

THR 713 LEU 714 0.0001

LEU 714 ALA 715 -0.0003

ALA 715 ASP 716 0.0002

ASP 716 THR 717 -0.0001

THR 717 THR 718 0.0000

THR 718 LYS 719 0.0000

LYS 719 MET 1 -0.0768

MET 1 SER 2 -0.0001

SER 2 GLN 3 -0.0001

GLN 3 PRO 4 -0.0003

PRO 4 ARG 5 0.0002

ARG 5 GLY 6 0.0002

GLY 6 GLY 7 0.0000

GLY 7 ARG 8 -0.0000

ARG 8 GLY 9 0.0458

GLY 9 GLY 10 -0.0000

GLY 10 GLY 11 -0.0000

GLY 11 ARG 12 0.0001

ARG 12 GLY 13 -0.0000

GLY 13 GLY 14 0.0001

GLY 14 GLY 15 0.0001

GLY 15 VAL 16 -0.0001

VAL 16 GLY 17 0.3496

GLY 17 ARG 18 0.0000

ARG 18 LYS 19 -0.0000

LYS 19 THR 20 -0.0001

THR 20 PRO 21 0.0000

PRO 21 SER 22 -0.0001

SER 22 SER 23 0.0002

SER 23 LEU 24 -0.0001

LEU 24 THR 25 -0.0493

THR 25 GLY 26 -0.0001

GLY 26 PRO 27 -0.0001

PRO 27 PRO 28 0.0000

PRO 28 ASP 29 0.0002

ASP 29 GLU 30 -0.0000

GLU 30 SER 31 0.0002

SER 31 ALA 32 -0.0000

ALA 32 THR 33 -0.0903

THR 33 PRO 34 0.0002

PRO 34 SER 35 0.0001

SER 35 GLU 36 -0.0003

GLU 36 ARG 37 0.0001

ARG 37 ALA 38 0.0001

ALA 38 THR 39 -0.0001

THR 39 PRO 40 -0.0001

PRO 40 ALA 41 0.0015

ALA 41 SER 42 0.0003

SER 42 LYS 43 0.0002

LYS 43 ALA 44 -0.0000

ALA 44 ASP 45 -0.0001

ASP 45 SER 46 0.0001

SER 46 ASP 47 -0.0003

ASP 47 PRO 48 -0.0001

PRO 48 LYS 49 0.0521

LYS 49 ASP 50 0.0001

ASP 50 ASP 51 -0.0001

ASP 51 SER 52 -0.0002

SER 52 SER 53 0.0001

SER 53 SER 54 -0.0002

SER 54 ASN 55 0.0002

ASN 55 GLY 56 0.0000

GLY 56 ASP 57 -0.3694

ASP 57 LYS 58 0.0001

LYS 58 LYS 59 0.0001

LYS 59 ASP 60 0.0002

ASP 60 MET 61 -0.0002

MET 61 ASP 62 0.0001

ASP 62 LEU 63 0.0001

LEU 63 PHE 64 0.0000

PHE 64 PRO 65 -0.1932

PRO 65 ALA 66 0.0000

ALA 66 PRO 67 -0.0000

PRO 67 LYS 68 0.0003

LYS 68 PRO 69 -0.0000

PRO 69 PRO 70 -0.0001

PRO 70 SER 71 0.0002

SER 71 ALA 72 -0.0002

ALA 72 GLY 73 0.5348

GLY 73 ALA 74 0.0001

ALA 74 SER 75 0.0004

SER 75 ILE 76 -0.0002

ILE 76 ARG 77 0.0003

ARG 77 ASP 78 -0.0001

ASP 78 THR 79 -0.0001

THR 79 ALA 80 -0.0001

ALA 80 ASN 81 0.0583

ASN 81 LYS 82 -0.0002

LYS 82 VAL 83 -0.0002

VAL 83 LEU 84 -0.0002

LEU 84 GLY 85 -0.0001

GLY 85 LEU 86 -0.0001

LEU 86 ALA 87 -0.0002

ALA 87 MET 88 -0.0003

MET 88 LYS 89 -0.0214

LYS 89 SER 90 -0.0001

SER 90 GLU 91 0.0003

GLU 91 TRP 92 -0.0002

TRP 92 THR 93 0.0002

THR 93 PRO 94 0.0002

PRO 94 ILE 95 -0.0001

ILE 95 GLU 96 0.0002

GLU 96 ALA 97 -0.0227

ALA 97 GLU 98 -0.0003

GLU 98 LEU 99 0.0002

LEU 99 LYS 100 -0.0004

LYS 100 LYS 101 0.0000

LYS 101 LEU 102 0.0000

LEU 102 GLU 103 -0.0002

GLU 103 LYS 104 -0.0001

LYS 104 TYR 105 -0.0359

TYR 105 VAL 106 -0.0002

VAL 106 ALA 107 -0.0003

ALA 107 ASN 108 0.0003

ASN 108 VAL 109 -0.0000

VAL 109 GLY 110 -0.0001

GLY 110 GLU 111 0.0004

GLU 111 ASP 112 -0.0003

ASP 112 GLY 113 0.1734

GLY 113 ASN 114 0.0003

ASN 114 HIS 115 -0.0003

HIS 115 ILE 116 0.0000

ILE 116 PRO 117 -0.0002

PRO 117 LEU 118 -0.0002

LEU 118 ALA 119 0.0000

ALA 119 GLY 120 0.0000

GLY 120 VAL 121 0.1134

VAL 121 HIS 122 0.0003

HIS 122 ASP 123 0.0001

ASP 123 MET 124 0.0001

MET 124 ASN 125 -0.0002

ASN 125 LEU 126 -0.0004

LEU 126 MET 127 0.0000

MET 127 GLU 128 -0.0002

GLU 128 ASP 129 -0.0665

ASP 129 LYS 130 -0.0001

LYS 130 ARG 131 -0.0002

ARG 131 PHE 132 0.0003

PHE 132 VAL 133 0.0001

VAL 133 TYR 134 -0.0001

TYR 134 ASN 135 -0.0002

ASN 135 LEU 136 0.0000

LEU 136 MET 137 0.0093

MET 137 VAL 138 0.0002

VAL 138 VAL 139 -0.0002

VAL 139 SER 140 -0.0003

SER 140 LYS 141 0.0002

LYS 141 ASN 142 -0.0005

ASN 142 HIS 143 -0.0002

HIS 143 ASN 144 -0.0000

ASN 144 ASN 145 0.0086

ASN 145 LYS 146 0.0002

LYS 146 PRO 147 0.0002

PRO 147 ILE 148 -0.0004

ILE 148 GLN 149 0.0003

GLN 149 GLU 150 0.0000

GLU 150 PHE 151 0.0004

PHE 151 VAL 152 0.0004

VAL 152 LEU 153 0.0008

LEU 153 VAL 154 -0.0001

VAL 154 SER 155 0.0002

SER 155 PRO 156 -0.0001

PRO 156 ALA 157 -0.0001

ALA 157 PRO 158 0.0001

PRO 158 VAL 159 -0.0001

VAL 159 ASP 160 -0.0002

ASP 160 THR 161 -0.0210

THR 161 ALA 162 -0.0002

ALA 162 ALA 163 0.0004

ALA 163 LYS 164 -0.0000

LYS 164 LEU 165 0.0002

LEU 165 SER 166 -0.0000

SER 166 ASN 167 -0.0005

ASN 167 ILE 168 -0.0001

ILE 168 TYR 169 -0.0024

TYR 169 ILE 170 -0.0004

ILE 170 VAL 171 -0.0003

VAL 171 LEU 172 0.0001

LEU 172 SER 173 -0.0001

SER 173 THR 174 -0.0002

THR 174 LYS 175 0.0001

LYS 175 GLU 176 0.0002

GLU 176 LYS 177 0.0114

LYS 177 GLU 178 0.0001

GLU 178 ARG 179 -0.0001

ARG 179 ALA 180 0.0000

ALA 180 LYS 181 -0.0003

LYS 181 ASP 182 0.0001

ASP 182 LEU 183 -0.0000

LEU 183 VAL 184 -0.0002

VAL 184 ALA 185 -0.0144

ALA 185 ALA 186 0.0001

ALA 186 GLY 187 0.0000

GLY 187 LYS 188 0.0001

LYS 188 GLN 189 -0.0004

GLN 189 CYS 190 0.0002

CYS 190 GLU 191 0.0000

GLU 191 ALA 192 0.0001

ALA 192 MET 193 -0.0696

MET 193 ALA 194 -0.0001

ALA 194 THR 195 -0.0002

THR 195 GLU 196 -0.0003

GLU 196 LEU 197 0.0000

LEU 197 LEU 198 -0.0001

LEU 198 ALA 199 0.0002

ALA 199 LEU 200 0.0000

LEU 200 ALA 201 0.0220

ALA 201 ALA 202 -0.0004

ALA 202 GLY 203 0.0001

GLY 203 SER 204 -0.0000

SER 204 ASP 205 0.0003

ASP 205 SER 206 -0.0003

SER 206 ALA 207 -0.0003

ALA 207 GLY 208 0.0000

GLY 208 LYS 209 -0.0079

LYS 209 ILE 210 -0.0004

ILE 210 LEU 211 -0.0001

LEU 211 GLN 212 0.0000

GLN 212 ALA 213 0.0002

ALA 213 THR 214 0.0001

THR 214 ASP 215 -0.0000

ASP 215 LYS 216 0.0000

LYS 216 ARG 217 -0.0173

ARG 217 ASN 218 -0.0002

ASN 218 VAL 219 -0.0001

VAL 219 GLU 220 0.0001

GLU 220 PHE 221 -0.0001

PHE 221 LEU 222 -0.0002

LEU 222 ASP 223 -0.0001

ASP 223 VAL 224 0.0002

VAL 224 LEU 225 0.0416

LEU 225 ILE 226 -0.0005

ILE 226 GLU 227 0.0004

GLU 227 ASN 228 0.0001

ASN 228 GLU 229 0.0002

GLU 229 GLN 230 0.0003

GLN 230 LYS 231 0.0003

LYS 231 GLU 232 0.0000

GLU 232 VAL 233 -0.0226

VAL 233 ILE 234 -0.0003

ILE 234 ALA 235 0.0002

ALA 235 HIS 236 0.0003

HIS 236 THR 237 -0.0002

THR 237 VAL 238 0.0002

VAL 238 VAL 239 0.0001

VAL 239 GLN 240 -0.0000

GLN 240 ARG 241 -0.0150

ARG 241 TYR 242 -0.0003

TYR 242 LEU 243 -0.0002

LEU 243 GLN 244 -0.0000

GLN 244 GLU 245 0.0003

GLU 245 LEU 246 -0.0003

LEU 246 TRP 247 -0.0001

TRP 247 HIS 248 -0.0003

HIS 248 GLY 249 0.0339

GLY 249 SER 250 -0.0003

SER 250 LEU 251 0.0002

LEU 251 THR 252 -0.0004

THR 252 TRP 253 0.0002

TRP 253 ALA 254 -0.0000

ALA 254 SER 255 0.0001

SER 255 TRP 256 -0.0004

TRP 256 LYS 257 0.0045

LYS 257 ILE 258 -0.0001

ILE 258 LEU 259 0.0004

LEU 259 LEU 260 -0.0001

LEU 260 LEU 261 0.0002

LEU 261 LEU 262 0.0001

LEU 262 VAL 263 0.0001

VAL 263 ALA 264 0.0002

ALA 264 PHE 265 -0.0125

PHE 265 ILE 266 -0.0000

ILE 266 VAL 267 0.0003

VAL 267 CYS 268 -0.0000

CYS 268 PRO 269 -0.0001

PRO 269 PRO 270 0.0005

PRO 270 VAL 271 0.0001

VAL 271 TRP 272 0.0002

TRP 272 ILE 273 0.0015

ILE 273 GLY 274 -0.0001

GLY 274 PHE 275 0.0002

PHE 275 THR 276 -0.0004

THR 276 PHE 277 0.0001

PHE 277 PRO 278 0.0005

PRO 278 MET 279 -0.0002

MET 279 GLY 280 0.0001

GLY 280 HIS 281 0.0287

HIS 281 LYS 282 -0.0003

LYS 282 PHE 283 0.0001

PHE 283 ASN 284 0.0001

ASN 284 LYS 285 -0.0001

LYS 285 VAL 286 -0.0003

VAL 286 PRO 287 0.0004

PRO 287 ILE 288 0.0001

ILE 288 ILE 289 0.0370

ILE 289 LYS 290 0.0004

LYS 290 PHE 291 0.0002

PHE 291 MET 292 -0.0002

MET 292 SER 293 -0.0000

SER 293 TYR 294 -0.0003

TYR 294 LEU 295 -0.0004

LEU 295 THR 296 -0.0001

THR 296 SER 297 0.0192

SER 297 HIS 298 0.0000

HIS 298 ILE 299 -0.0003

ILE 299 TYR 300 0.0002

TYR 300 LEU 301 0.0001

LEU 301 MET 302 0.0001

MET 302 ILE 303 -0.0001

ILE 303 HIS 304 -0.0000

HIS 304 LEU 305 -0.0302

LEU 305 SER 306 -0.0001

SER 306 ILE 307 -0.0003

ILE 307 VAL 308 0.0000

VAL 308 GLY 309 -0.0002

GLY 309 ILE 310 0.0000

ILE 310 THR 311 0.0001

THR 311 PRO 312 0.0000

PRO 312 ILE 313 -0.0211

ILE 313 TYR 314 0.0003

TYR 314 PRO 315 0.0001

PRO 315 VAL 316 -0.0005

VAL 316 LEU 317 -0.0000

LEU 317 ARG 318 -0.0001

ARG 318 LEU 319 -0.0001

LEU 319 SER 320 0.0003

SER 320 LEU 321 -0.0040

LEU 321 VAL 322 0.0001

VAL 322 PRO 323 0.0002

PRO 323 TYR 324 -0.0001

TYR 324 TRP 325 -0.0001

TRP 325 TYR 326 0.0002

TYR 326 GLU 327 -0.0000

GLU 327 VAL 328 0.0003

VAL 328 GLY 329 0.0032

GLY 329 LEU 330 0.0001

LEU 330 LEU 331 0.0000

LEU 331 ILE 332 -0.0002

ILE 332 TRP 333 -0.0001

TRP 333 LEU 334 -0.0002

LEU 334 SER 335 0.0002

SER 335 GLY 336 -0.0001

GLY 336 LEU 337 -0.0078

LEU 337 LEU 338 -0.0005

LEU 338 LEU 339 -0.0000

LEU 339 PHE 340 0.0002

PHE 340 GLU 341 0.0001

GLU 341 LEU 342 -0.0002

LEU 342 THR 343 -0.0002

THR 343 ASN 344 0.0001

ASN 344 PRO 345 -0.0013

PRO 345 SER 346 0.0000

SER 346 ASP 347 0.0003

ASP 347 LYS 348 0.0002

LYS 348 SER 349 -0.0001

SER 349 GLY 350 0.0001

GLY 350 LEU 351 0.0000

LEU 351 GLY 352 -0.0001

GLY 352 SER 353 0.0133

SER 353 ILE 354 0.0002

ILE 354 LYS 355 -0.0004

LYS 355 VAL 356 -0.0001

VAL 356 LEU 357 -0.0001

LEU 357 VAL 358 0.0000

VAL 358 LEU 359 0.0000

LEU 359 LEU 360 -0.0002

LEU 360 LEU 361 0.0201

LEU 361 GLY 362 -0.0003

GLY 362 MET 363 0.0001

MET 363 ALA 364 0.0000

ALA 364 GLY 365 0.0004

GLY 365 VAL 366 0.0001

VAL 366 GLY 367 -0.0002

GLY 367 VAL 368 -0.0001

VAL 368 HIS 369 0.0053

HIS 369 VAL 370 -0.0002

VAL 370 SER 371 0.0003

SER 371 ALA 372 0.0000

ALA 372 PHE 373 0.0000

PHE 373 LEU 374 0.0000

LEU 374 PHE 375 -0.0001

PHE 375 VAL 376 0.0001

VAL 376 SER 377 0.0127

SER 377 LYS 378 0.0001

LYS 378 GLU 379 -0.0000

GLU 379 TYR 380 -0.0003

TYR 380 TRP 381 -0.0001

TRP 381 PRO 382 0.0003

PRO 382 THR 383 -0.0003

THR 383 LEU 384 0.0001

LEU 384 VAL 385 0.0091

VAL 385 TYR 386 0.0001

TYR 386 CYS 387 0.0002

CYS 387 ARG 388 -0.0002

ARG 388 ASN 389 -0.0001

ASN 389 GLN 390 0.0000

GLN 390 CYS 391 0.0004

CYS 391 PHE 392 -0.0002

PHE 392 ALA 393 0.0096

ALA 393 LEU 394 0.0001

LEU 394 ALA 395 0.0001

ALA 395 PHE 396 -0.0001

PHE 396 LEU 397 -0.0001

LEU 397 LEU 398 0.0004

LEU 398 ALA 399 0.0002

ALA 399 CYS 400 -0.0001

CYS 400 VAL 401 0.0168

VAL 401 GLN 402 0.0001

GLN 402 ILE 403 -0.0001

ILE 403 LEU 404 0.0004

LEU 404 ASP 405 -0.0000

ASP 405 PHE 406 -0.0000

PHE 406 LEU 407 -0.0001

LEU 407 SER 408 -0.0001

SER 408 PHE 409 0.0129

PHE 409 HIS 410 0.0002

HIS 410 HIS 411 -0.0001

HIS 411 LEU 412 0.0001

LEU 412 PHE 413 -0.0001

PHE 413 GLY 414 0.0003

GLY 414 PRO 415 -0.0002

PRO 415 TRP 416 -0.0004

TRP 416 ALA 417 -0.0142

ALA 417 ILE 418 -0.0002

ILE 418 ILE 419 0.0001

ILE 419 ILE 420 -0.0002

ILE 420 GLY 421 -0.0006

GLY 421 ASP 422 0.0001

ASP 422 LEU 423 -0.0001

LEU 423 LEU 424 0.0001

LEU 424 LYS 425 -0.0649

LYS 425 ASP 426 0.0000

ASP 426 LEU 427 -0.0002

LEU 427 ALA 428 -0.0002

ALA 428 ARG 429 0.0002

ARG 429 PHE 430 -0.0000

PHE 430 LEU 431 0.0001

LEU 431 ALA 432 -0.0001

ALA 432 VAL 433 -0.0383

VAL 433 LEU 434 0.0001

LEU 434 ALA 435 -0.0002

ALA 435 ILE 436 0.0000

ILE 436 PHE 437 0.0004

PHE 437 VAL 438 -0.0002

VAL 438 PHE 439 -0.0001

PHE 439 GLY 440 0.0004

GLY 440 PHE 441 -0.0057

PHE 441 SER 442 -0.0003

SER 442 MET 443 0.0000

MET 443 HIS 444 -0.0003

HIS 444 ILE 445 0.0003

ILE 445 VAL 446 -0.0002

VAL 446 ALA 447 0.0001

ALA 447 LEU 448 0.0001

LEU 448 ASN 449 -0.0044

ASN 449 GLN 450 -0.0002

GLN 450 SER 451 -0.0001

SER 451 PHE 452 0.0001

PHE 452 ALA 453 -0.0004

ALA 453 ASN 454 0.0003

ASN 454 PHE 455 -0.0001

PHE 455 SER 456 -0.0000

SER 456 PRO 457 0.0167

PRO 457 GLU 458 -0.0000

GLU 458 ASP 459 0.0002

ASP 459 LEU 460 -0.0001

LEU 460 ARG 461 -0.0001

ARG 461 SER 462 -0.0000

SER 462 PHE 463 0.0001

PHE 463 GLU 464 0.0001

GLU 464 LYS 465 0.0049

LYS 465 LYS 466 -0.0002

LYS 466 ASN 467 -0.0001

ASN 467 ARG 468 -0.0003

ARG 468 ASN 469 0.0001

ASN 469 ARG 470 0.0003

ARG 470 GLY 471 -0.0002

GLY 471 TYR 472 0.0001

TYR 472 PHE 473 -0.0110

PHE 473 SER 474 0.0001

SER 474 ASP 475 -0.0000

ASP 475 VAL 476 0.0002

VAL 476 ARG 477 -0.0001

ARG 477 MET 478 0.0001

MET 478 HIS 479 -0.0001

HIS 479 PRO 480 0.0002

PRO 480 ILE 481 -0.1197

ILE 481 ASN 482 -0.0000

ASN 482 SER 483 -0.0002

SER 483 PHE 484 -0.0001

PHE 484 GLU 485 0.0001

GLU 485 LEU 486 -0.0001

LEU 486 LEU 487 -0.0002

LEU 487 PHE 488 -0.0001

PHE 488 PHE 489 0.0155

PHE 489 ALA 490 -0.0001

ALA 490 VAL 491 -0.0000

VAL 491 PHE 492 -0.0000

PHE 492 GLY 493 -0.0003

GLY 493 GLN 494 0.0002

GLN 494 THR 495 -0.0002

THR 495 THR 496 0.0001

THR 496 THR 497 0.0885

THR 497 GLU 498 0.0000

GLU 498 GLN 499 -0.0004

GLN 499 THR 500 -0.0003

THR 500 GLN 501 -0.0001

GLN 501 VAL 502 -0.0000

VAL 502 ASP 503 0.0003

ASP 503 LYS 504 0.0001

LYS 504 ILE 505 -0.0204

ILE 505 LYS 506 0.0002

LYS 506 ASN 507 -0.0000

ASN 507 VAL 508 0.0004

VAL 508 ALA 509 -0.0002

ALA 509 THR 510 0.0003

THR 510 PRO 511 -0.0002

PRO 511 THR 512 -0.0001

THR 512 GLN 513 0.0061

GLN 513 PRO 514 -0.0005

PRO 514 TYR 515 -0.0000

TYR 515 TRP 516 0.0003

TRP 516 VAL 517 -0.0003

VAL 517 GLU 518 -0.0001

GLU 518 TYR 519 -0.0001

TYR 519 LEU 520 0.0001

LEU 520 PHE 521 -0.0211

PHE 521 LYS 522 -0.0004

LYS 522 ILE 523 0.0002

ILE 523 VAL 524 0.0002

VAL 524 PHE 525 0.0003

PHE 525 GLY 526 0.0001

GLY 526 ILE 527 0.0003

ILE 527 TYR 528 0.0002

TYR 528 MET 529 -0.0046

MET 529 LEU 530 -0.0001

LEU 530 VAL 531 -0.0001

VAL 531 SER 532 0.0002

SER 532 VAL 533 0.0001

VAL 533 VAL 534 0.0000

VAL 534 VAL 535 -0.0004

VAL 535 LEU 536 -0.0001

LEU 536 ILE 537 0.0165

ILE 537 ASN 538 0.0001

ASN 538 LEU 539 0.0001

LEU 539 LEU 540 0.0002

LEU 540 ILE 541 -0.0002

ILE 541 ALA 542 0.0001

ALA 542 MET 543 0.0002

MET 543 MET 544 -0.0002

MET 544 SER 545 -0.0132

SER 545 ASP 546 0.0000

ASP 546 THR 547 0.0000

THR 547 TYR 548 0.0002

TYR 548 GLN 549 0.0001

GLN 549 ARG 550 0.0001

ARG 550 ILE 551 -0.0001

ILE 551 GLN 552 0.0000

GLN 552 ALA 553 0.0231

ALA 553 GLN 554 -0.0001

GLN 554 SER 555 0.0000

SER 555 ASP 556 0.0006

ASP 556 ILE 557 -0.0003

ILE 557 GLU 558 -0.0001

GLU 558 TRP 559 -0.0002

TRP 559 LYS 560 0.0002

LYS 560 PHE 561 0.0056

PHE 561 GLY 562 -0.0001

GLY 562 LEU 563 -0.0001

LEU 563 SER 564 -0.0001

SER 564 LYS 565 0.0003

LYS 565 LEU 566 0.0002

LEU 566 ILE 567 0.0001

ILE 567 ARG 568 -0.0004

ARG 568 ASN 569 -0.0118

ASN 569 MET 570 -0.0001

MET 570 HIS 571 -0.0001

HIS 571 ARG 572 0.0000

ARG 572 THR 573 0.0000

THR 573 THR 574 0.0003

THR 574 THR 575 -0.0001

THR 575 ALA 576 0.0001

ALA 576 PRO 577 -0.0488

PRO 577 SER 578 0.0003

SER 578 PRO 579 -0.0003

PRO 579 LEU 580 -0.0000

LEU 580 ASN 581 -0.0000

ASN 581 LEU 582 0.0000

LEU 582 VAL 583 0.0000

VAL 583 THR 584 -0.0002

THR 584 THR 585 0.0292

THR 585 TRP 586 -0.0001

TRP 586 PHE 587 -0.0001

PHE 587 MET 588 0.0003

MET 588 TRP 589 -0.0001

TRP 589 ARG 657 -0.0165

ARG 657 ILE 658 0.0001

ILE 658 GLU 659 -0.0004

GLU 659 ASN 660 0.0003

ASN 660 VAL 661 0.0001

VAL 661 ALA 662 0.0000

ALA 662 ASP 663 0.0004

ASP 663 TRP 664 -0.0000

TRP 664 GLU 665 0.0078

GLU 665 ALA 666 -0.0000

ALA 666 ILE 667 -0.0001

ILE 667 ALA 668 0.0001

ALA 668 LYS 669 -0.0004

LYS 669 LYS 670 0.0001

LYS 670 TYR 671 0.0001

TYR 671 ARG 672 0.0003

ARG 672 ALA 673 0.0063

ALA 673 LEU 674 0.0000

LEU 674 VAL 675 0.0001

VAL 675 GLY 676 -0.0001

GLY 676 ASP 677 -0.0002

ASP 677 GLU 678 0.0001

GLU 678 GLU 679 -0.0003

GLU 679 GLY 680 0.0004

GLY 680 GLY 681 0.3040

GLY 681 SER 682 -0.0001

SER 682 LEU 683 -0.0002

LEU 683 LYS 684 -0.0001

LYS 684 ASP 685 0.0001

ASP 685 SER 686 0.0000

SER 686 ASP 687 -0.0000

ASP 687 ALA 688 0.0003

ALA 688 GLU 689 0.1961

GLU 689 SER 690 -0.0000

SER 690 GLY 691 -0.0001

GLY 691 SER 692 -0.0000

SER 692 GLN 693 0.0002

GLN 693 GLU 694 -0.0001

GLU 694 GLY 695 0.0001

GLY 695 SER 696 0.0001

SER 696 GLY 697 0.1872

GLY 697 GLY 698 0.0000

GLY 698 GLN 699 -0.0000

GLN 699 GLN 700 -0.0002

GLN 700 PRO 701 0.0000

PRO 701 PRO 702 -0.0001

PRO 702 ALA 703 -0.0000

ALA 703 GLN 704 0.0001

GLN 704 VAL 705 -0.0762

VAL 705 GLY 706 0.0004

GLY 706 ARG 707 0.0000

ARG 707 ARG 708 0.0000

ARG 708 ALA 709 -0.0002

ALA 709 ILE 710 -0.0001

ILE 710 LYS 711 -0.0003

LYS 711 ALA 712 0.0002

ALA 712 THR 713 -0.1748

THR 713 LEU 714 0.0001

LEU 714 ALA 715 0.0003

ALA 715 ASP 716 0.0001

ASP 716 THR 717 -0.0000

THR 717 THR 718 0.0000

THR 718 LYS 719 0.0001

LYS 719 MET 1 0.0096

MET 1 SER 2 0.0003

SER 2 GLN 3 0.0001

GLN 3 PRO 4 0.0000

PRO 4 ARG 5 -0.0002

ARG 5 GLY 6 0.0001

GLY 6 GLY 7 -0.0000

GLY 7 ARG 8 -0.0002

ARG 8 GLY 9 -0.0164

GLY 9 GLY 10 -0.0000

GLY 10 GLY 11 -0.0000

GLY 11 ARG 12 0.0002

ARG 12 GLY 13 -0.0003

GLY 13 GLY 14 0.0001

GLY 14 GLY 15 0.0000

GLY 15 VAL 16 -0.0004

VAL 16 GLY 17 -0.0138

GLY 17 ARG 18 0.0001

ARG 18 LYS 19 -0.0003

LYS 19 THR 20 0.0000

THR 20 PRO 21 0.0000

PRO 21 SER 22 0.0000

SER 22 SER 23 0.0002

SER 23 LEU 24 -0.0001

LEU 24 THR 25 -0.0257

THR 25 GLY 26 0.0001

GLY 26 PRO 27 -0.0001

PRO 27 PRO 28 0.0002

PRO 28 ASP 29 -0.0003

ASP 29 GLU 30 0.0002

GLU 30 SER 31 -0.0002

SER 31 ALA 32 -0.0001

ALA 32 THR 33 0.0201

THR 33 PRO 34 0.0001

PRO 34 SER 35 -0.0000

SER 35 GLU 36 -0.0002

GLU 36 ARG 37 0.0000

ARG 37 ALA 38 -0.0000

ALA 38 THR 39 -0.0001

THR 39 PRO 40 -0.0003

PRO 40 ALA 41 -0.1421

ALA 41 SER 42 -0.0003

SER 42 LYS 43 -0.0002

LYS 43 ALA 44 -0.0001

ALA 44 ASP 45 -0.0002

ASP 45 SER 46 0.0000

SER 46 ASP 47 0.0002

ASP 47 PRO 48 -0.0001

PRO 48 LYS 49 -0.0623

LYS 49 ASP 50 -0.0003

ASP 50 ASP 51 -0.0000

ASP 51 SER 52 0.0003

SER 52 SER 53 0.0001

SER 53 SER 54 -0.0000

SER 54 ASN 55 -0.0001

ASN 55 GLY 56 -0.0002

GLY 56 ASP 57 0.2422

ASP 57 LYS 58 0.0002

LYS 58 LYS 59 -0.0002

LYS 59 ASP 60 0.0004

ASP 60 MET 61 -0.0001

MET 61 ASP 62 0.0000

ASP 62 LEU 63 -0.0002

LEU 63 PHE 64 -0.0001

PHE 64 PRO 65 0.1864

PRO 65 ALA 66 -0.0004

ALA 66 PRO 67 0.0000

PRO 67 LYS 68 0.0002

LYS 68 PRO 69 0.0003

PRO 69 PRO 70 -0.0001

PRO 70 SER 71 0.0003

SER 71 ALA 72 0.0003

ALA 72 GLY 73 -0.2181

GLY 73 ALA 74 0.0004

ALA 74 SER 75 0.0003

SER 75 ILE 76 0.0002

ILE 76 ARG 77 -0.0001

ARG 77 ASP 78 0.0002

ASP 78 THR 79 -0.0000

THR 79 ALA 80 0.0001

ALA 80 ASN 81 0.0057

ASN 81 LYS 82 -0.0001

LYS 82 VAL 83 0.0003

VAL 83 LEU 84 0.0002

LEU 84 GLY 85 0.0001

GLY 85 LEU 86 0.0004

LEU 86 ALA 87 0.0003

ALA 87 MET 88 0.0000

MET 88 LYS 89 0.0093

LYS 89 SER 90 0.0001

SER 90 GLU 91 -0.0004

GLU 91 TRP 92 -0.0000

TRP 92 THR 93 -0.0001

THR 93 PRO 94 0.0003

PRO 94 ILE 95 -0.0004

ILE 95 GLU 96 -0.0002

GLU 96 ALA 97 0.0337

ALA 97 GLU 98 0.0001

GLU 98 LEU 99 0.0002

LEU 99 LYS 100 -0.0002

LYS 100 LYS 101 0.0003

LYS 101 LEU 102 0.0002

LEU 102 GLU 103 -0.0002

GLU 103 LYS 104 -0.0004

LYS 104 TYR 105 0.0602

TYR 105 VAL 106 0.0000

VAL 106 ALA 107 -0.0001

ALA 107 ASN 108 -0.0001

ASN 108 VAL 109 -0.0001

VAL 109 GLY 110 0.0001

GLY 110 GLU 111 0.0003

GLU 111 ASP 112 0.0001

ASP 112 GLY 113 -0.1349

GLY 113 ASN 114 -0.0000

ASN 114 HIS 115 -0.0002

HIS 115 ILE 116 0.0000

ILE 116 PRO 117 -0.0004

PRO 117 LEU 118 0.0001

LEU 118 ALA 119 0.0004

ALA 119 GLY 120 0.0001

GLY 120 VAL 121 -0.1626

VAL 121 HIS 122 -0.0002

HIS 122 ASP 123 0.0002

ASP 123 MET 124 -0.0005

MET 124 ASN 125 0.0001

ASN 125 LEU 126 -0.0003

LEU 126 MET 127 -0.0002

MET 127 GLU 128 0.0002

GLU 128 ASP 129 0.0727

ASP 129 LYS 130 -0.0002

LYS 130 ARG 131 -0.0004

ARG 131 PHE 132 -0.0002

PHE 132 VAL 133 0.0000

VAL 133 TYR 134 -0.0000

TYR 134 ASN 135 0.0002

ASN 135 LEU 136 -0.0004

LEU 136 MET 137 0.0000

MET 137 VAL 138 0.0001

VAL 138 VAL 139 -0.0001

VAL 139 SER 140 0.0002

SER 140 LYS 141 -0.0002

LYS 141 ASN 142 0.0004

ASN 142 HIS 143 -0.0001

HIS 143 ASN 144 -0.0002

ASN 144 ASN 145 0.0142

ASN 145 LYS 146 0.0002

LYS 146 PRO 147 0.0002

PRO 147 ILE 148 -0.0004

ILE 148 GLN 149 0.0001

GLN 149 GLU 150 -0.0000

GLU 150 PHE 151 -0.0001

PHE 151 VAL 152 0.0003

VAL 152 LEU 153 0.0055

LEU 153 VAL 154 0.0002

VAL 154 SER 155 0.0001

SER 155 PRO 156 0.0001

PRO 156 ALA 157 0.0002

ALA 157 PRO 158 0.0002

PRO 158 VAL 159 0.0001

VAL 159 ASP 160 -0.0002

ASP 160 THR 161 0.0314

THR 161 ALA 162 -0.0003

ALA 162 ALA 163 0.0000

ALA 163 LYS 164 -0.0001

LYS 164 LEU 165 -0.0001

LEU 165 SER 166 -0.0001

SER 166 ASN 167 -0.0001

ASN 167 ILE 168 -0.0002

ILE 168 TYR 169 0.0234

TYR 169 ILE 170 -0.0003

ILE 170 VAL 171 0.0000

VAL 171 LEU 172 0.0001

LEU 172 SER 173 -0.0002

SER 173 THR 174 -0.0001

THR 174 LYS 175 -0.0000

LYS 175 GLU 176 -0.0000

GLU 176 LYS 177 -0.0255

LYS 177 GLU 178 0.0002

GLU 178 ARG 179 -0.0003

ARG 179 ALA 180 0.0001

ALA 180 LYS 181 -0.0002

LYS 181 ASP 182 -0.0002

ASP 182 LEU 183 -0.0002

LEU 183 VAL 184 0.0001

VAL 184 ALA 185 -0.0171

ALA 185 ALA 186 -0.0000

ALA 186 GLY 187 0.0001

GLY 187 LYS 188 0.0002

LYS 188 GLN 189 0.0000

GLN 189 CYS 190 0.0001

CYS 190 GLU 191 0.0000

GLU 191 ALA 192 0.0004

ALA 192 MET 193 0.0670

MET 193 ALA 194 -0.0003

ALA 194 THR 195 0.0002

THR 195 GLU 196 -0.0002

GLU 196 LEU 197 0.0001

LEU 197 LEU 198 0.0001

LEU 198 ALA 199 0.0002

ALA 199 LEU 200 -0.0001

LEU 200 ALA 201 -0.0138

ALA 201 ALA 202 0.0004

ALA 202 GLY 203 0.0000

GLY 203 SER 204 -0.0002

SER 204 ASP 205 0.0002

ASP 205 SER 206 -0.0000

SER 206 ALA 207 0.0004

ALA 207 GLY 208 -0.0001

GLY 208 LYS 209 0.0078

LYS 209 ILE 210 0.0000

ILE 210 LEU 211 -0.0004

LEU 211 GLN 212 0.0004

GLN 212 ALA 213 0.0001

ALA 213 THR 214 0.0000

THR 214 ASP 215 -0.0002

ASP 215 LYS 216 -0.0000

LYS 216 ARG 217 0.0030

ARG 217 ASN 218 0.0001

ASN 218 VAL 219 -0.0001

VAL 219 GLU 220 -0.0001

GLU 220 PHE 221 0.0001

PHE 221 LEU 222 0.0003

LEU 222 ASP 223 -0.0005

ASP 223 VAL 224 -0.0000

VAL 224 LEU 225 -0.0390

LEU 225 ILE 226 0.0002

ILE 226 GLU 227 0.0000

GLU 227 ASN 228 0.0005

ASN 228 GLU 229 -0.0002

GLU 229 GLN 230 0.0000

GLN 230 LYS 231 -0.0002

LYS 231 GLU 232 0.0001

GLU 232 VAL 233 0.0181

VAL 233 ILE 234 -0.0002

ILE 234 ALA 235 0.0004

ALA 235 HIS 236 0.0003

HIS 236 THR 237 -0.0000

THR 237 VAL 238 -0.0004

VAL 238 VAL 239 0.0002

VAL 239 GLN 240 -0.0001

GLN 240 ARG 241 0.0188

ARG 241 TYR 242 -0.0002

TYR 242 LEU 243 -0.0001

LEU 243 GLN 244 0.0002

GLN 244 GLU 245 0.0005

GLU 245 LEU 246 0.0002

LEU 246 TRP 247 0.0001

TRP 247 HIS 248 -0.0000

HIS 248 GLY 249 -0.0535

GLY 249 SER 250 -0.0000

SER 250 LEU 251 -0.0000

LEU 251 THR 252 -0.0001

THR 252 TRP 253 -0.0000

TRP 253 ALA 254 0.0002

ALA 254 SER 255 0.0000

SER 255 TRP 256 -0.0000

TRP 256 LYS 257 -0.0038

LYS 257 ILE 258 -0.0000

ILE 258 LEU 259 0.0004

LEU 259 LEU 260 -0.0003

LEU 260 LEU 261 0.0000

LEU 261 LEU 262 -0.0001

LEU 262 VAL 263 0.0002

VAL 263 ALA 264 0.0001

ALA 264 PHE 265 0.0164

PHE 265 ILE 266 -0.0004

ILE 266 VAL 267 -0.0003

VAL 267 CYS 268 -0.0000

CYS 268 PRO 269 -0.0000

PRO 269 PRO 270 -0.0000

PRO 270 VAL 271 0.0001

VAL 271 TRP 272 0.0002

TRP 272 ILE 273 -0.0042

ILE 273 GLY 274 -0.0002

GLY 274 PHE 275 0.0001

PHE 275 THR 276 0.0001

THR 276 PHE 277 0.0001

PHE 277 PRO 278 0.0003

PRO 278 MET 279 -0.0004

MET 279 GLY 280 -0.0001

GLY 280 HIS 281 -0.0272

HIS 281 LYS 282 -0.0002

LYS 282 PHE 283 0.0004

PHE 283 ASN 284 0.0005

ASN 284 LYS 285 0.0002

LYS 285 VAL 286 -0.0002

VAL 286 PRO 287 0.0001

PRO 287 ILE 288 0.0001

ILE 288 ILE 289 -0.0272

ILE 289 LYS 290 -0.0001

LYS 290 PHE 291 -0.0002

PHE 291 MET 292 -0.0003

MET 292 SER 293 -0.0001

SER 293 TYR 294 0.0001

TYR 294 LEU 295 0.0003

LEU 295 THR 296 -0.0000

THR 296 SER 297 -0.0137

SER 297 HIS 298 0.0000

HIS 298 ILE 299 -0.0000

ILE 299 TYR 300 0.0002

TYR 300 LEU 301 0.0002

LEU 301 MET 302 -0.0005

MET 302 ILE 303 0.0001

ILE 303 HIS 304 -0.0002

HIS 304 LEU 305 0.0420

LEU 305 SER 306 0.0004

SER 306 ILE 307 -0.0002

ILE 307 VAL 308 -0.0001

VAL 308 GLY 309 -0.0000

GLY 309 ILE 310 -0.0000

ILE 310 THR 311 0.0001

THR 311 PRO 312 0.0001

PRO 312 ILE 313 0.0206

ILE 313 TYR 314 -0.0004

TYR 314 PRO 315 0.0004

PRO 315 VAL 316 0.0003

VAL 316 LEU 317 -0.0002

LEU 317 ARG 318 0.0001

ARG 318 LEU 319 -0.0001

LEU 319 SER 320 -0.0001

SER 320 LEU 321 -0.0005

LEU 321 VAL 322 0.0004

VAL 322 PRO 323 -0.0001

PRO 323 TYR 324 0.0004

TYR 324 TRP 325 0.0002

TRP 325 TYR 326 0.0001

TYR 326 GLU 327 0.0004

GLU 327 VAL 328 -0.0003

VAL 328 GLY 329 0.0035

GLY 329 LEU 330 -0.0002

LEU 330 LEU 331 0.0001

LEU 331 ILE 332 0.0001

ILE 332 TRP 333 0.0001

TRP 333 LEU 334 0.0001

LEU 334 SER 335 0.0001

SER 335 GLY 336 -0.0001

GLY 336 LEU 337 0.0057

LEU 337 LEU 338 0.0000

LEU 338 LEU 339 0.0004

LEU 339 PHE 340 -0.0002

PHE 340 GLU 341 -0.0002

GLU 341 LEU 342 0.0001

LEU 342 THR 343 0.0001

THR 343 ASN 344 0.0001

ASN 344 PRO 345 0.0037

PRO 345 SER 346 0.0000

SER 346 ASP 347 0.0002

ASP 347 LYS 348 -0.0001

LYS 348 SER 349 -0.0001

SER 349 GLY 350 -0.0000

GLY 350 LEU 351 -0.0002

LEU 351 GLY 352 -0.0001

GLY 352 SER 353 -0.0259

SER 353 ILE 354 0.0002

ILE 354 LYS 355 0.0001

LYS 355 VAL 356 -0.0001

VAL 356 LEU 357 0.0001

LEU 357 VAL 358 0.0001

VAL 358 LEU 359 -0.0003

LEU 359 LEU 360 0.0003

LEU 360 LEU 361 -0.0257

LEU 361 GLY 362 0.0001

GLY 362 MET 363 -0.0003

MET 363 ALA 364 -0.0003

ALA 364 GLY 365 -0.0003

GLY 365 VAL 366 -0.0004

VAL 366 GLY 367 -0.0002

GLY 367 VAL 368 0.0001

VAL 368 HIS 369 -0.0147

HIS 369 VAL 370 -0.0002

VAL 370 SER 371 -0.0002

SER 371 ALA 372 -0.0003

ALA 372 PHE 373 -0.0003

PHE 373 LEU 374 0.0001

LEU 374 PHE 375 -0.0001

PHE 375 VAL 376 -0.0001

VAL 376 SER 377 -0.0195

SER 377 LYS 378 -0.0001

LYS 378 GLU 379 0.0001

GLU 379 TYR 380 -0.0000

TYR 380 TRP 381 -0.0003

TRP 381 PRO 382 0.0001

PRO 382 THR 383 -0.0001

THR 383 LEU 384 0.0001

LEU 384 VAL 385 -0.0072

VAL 385 TYR 386 -0.0002

TYR 386 CYS 387 0.0001

CYS 387 ARG 388 0.0002

ARG 388 ASN 389 -0.0002

ASN 389 GLN 390 -0.0001

GLN 390 CYS 391 -0.0002

CYS 391 PHE 392 0.0000

PHE 392 ALA 393 -0.0092

ALA 393 LEU 394 -0.0001

LEU 394 ALA 395 0.0002

ALA 395 PHE 396 -0.0000

PHE 396 LEU 397 -0.0002

LEU 397 LEU 398 0.0001

LEU 398 ALA 399 -0.0004

ALA 399 CYS 400 0.0000

CYS 400 VAL 401 -0.0146

VAL 401 GLN 402 -0.0004

GLN 402 ILE 403 0.0000

ILE 403 LEU 404 -0.0001

LEU 404 ASP 405 0.0002

ASP 405 PHE 406 0.0003

PHE 406 LEU 407 -0.0002

LEU 407 SER 408 0.0002

SER 408 PHE 409 -0.0112

PHE 409 HIS 410 -0.0002

HIS 410 HIS 411 0.0000

HIS 411 LEU 412 -0.0003

LEU 412 PHE 413 0.0003

PHE 413 GLY 414 0.0005

GLY 414 PRO 415 0.0001

PRO 415 TRP 416 0.0001

TRP 416 ALA 417 0.0148

ALA 417 ILE 418 0.0003

ILE 418 ILE 419 -0.0001

ILE 419 ILE 420 -0.0002

ILE 420 GLY 421 -0.0004

GLY 421 ASP 422 0.0001

ASP 422 LEU 423 -0.0003

LEU 423 LEU 424 -0.0001

LEU 424 LYS 425 0.0701

LYS 425 ASP 426 -0.0001

ASP 426 LEU 427 0.0001

LEU 427 ALA 428 0.0000

ALA 428 ARG 429 -0.0001

ARG 429 PHE 430 -0.0001

PHE 430 LEU 431 0.0001

LEU 431 ALA 432 0.0001

ALA 432 VAL 433 0.0475

VAL 433 LEU 434 -0.0001

LEU 434 ALA 435 -0.0001

ALA 435 ILE 436 0.0002

ILE 436 PHE 437 -0.0004

PHE 437 VAL 438 -0.0000

VAL 438 PHE 439 0.0000

PHE 439 GLY 440 -0.0001

GLY 440 PHE 441 0.0112

PHE 441 SER 442 0.0001

SER 442 MET 443 0.0005

MET 443 HIS 444 0.0000

HIS 444 ILE 445 0.0003

ILE 445 VAL 446 -0.0001

VAL 446 ALA 447 -0.0002

ALA 447 LEU 448 0.0003

LEU 448 ASN 449 0.0029

ASN 449 GLN 450 0.0002

GLN 450 SER 451 0.0002

SER 451 PHE 452 -0.0000

PHE 452 ALA 453 -0.0001

ALA 453 ASN 454 0.0001

ASN 454 PHE 455 -0.0002

PHE 455 SER 456 0.0001

SER 456 PRO 457 -0.0145

PRO 457 GLU 458 0.0000

GLU 458 ASP 459 0.0001

ASP 459 LEU 460 -0.0003

LEU 460 ARG 461 -0.0004

ARG 461 SER 462 -0.0003

SER 462 PHE 463 0.0001

PHE 463 GLU 464 -0.0001

GLU 464 LYS 465 -0.0146

LYS 465 LYS 466 -0.0001

LYS 466 ASN 467 0.0000

ASN 467 ARG 468 -0.0000

ARG 468 ASN 469 0.0002

ASN 469 ARG 470 0.0000

ARG 470 GLY 471 -0.0002

GLY 471 TYR 472 -0.0000

TYR 472 PHE 473 0.0215

PHE 473 SER 474 0.0002

SER 474 ASP 475 0.0001

ASP 475 VAL 476 0.0002

VAL 476 ARG 477 -0.0001

ARG 477 MET 478 -0.0000

MET 478 HIS 479 -0.0004

HIS 479 PRO 480 0.0000

PRO 480 ILE 481 0.1959

ILE 481 ASN 482 0.0002

ASN 482 SER 483 -0.0001

SER 483 PHE 484 0.0003

PHE 484 GLU 485 -0.0001

GLU 485 LEU 486 0.0001

LEU 486 LEU 487 -0.0000

LEU 487 PHE 488 -0.0003

PHE 488 PHE 489 -0.0025

PHE 489 ALA 490 0.0004

ALA 490 VAL 491 -0.0003

VAL 491 PHE 492 0.0000

PHE 492 GLY 493 0.0003

GLY 493 GLN 494 -0.0000

GLN 494 THR 495 -0.0001

THR 495 THR 496 -0.0000

THR 496 THR 497 -0.0901

THR 497 GLU 498 0.0001

GLU 498 GLN 499 -0.0002

GLN 499 THR 500 -0.0005

THR 500 GLN 501 -0.0000

GLN 501 VAL 502 -0.0001

VAL 502 ASP 503 -0.0003

ASP 503 LYS 504 0.0000

LYS 504 ILE 505 0.0161

ILE 505 LYS 506 -0.0000

LYS 506 ASN 507 -0.0000

ASN 507 VAL 508 -0.0000

VAL 508 ALA 509 0.0001

ALA 509 THR 510 -0.0003

THR 510 PRO 511 0.0001

PRO 511 THR 512 -0.0005

THR 512 GLN 513 -0.0191

GLN 513 PRO 514 0.0001

PRO 514 TYR 515 0.0004

TYR 515 TRP 516 -0.0001

TRP 516 VAL 517 0.0001

VAL 517 GLU 518 -0.0003

GLU 518 TYR 519 0.0004

TYR 519 LEU 520 0.0003

LEU 520 PHE 521 0.0253

PHE 521 LYS 522 0.0002

LYS 522 ILE 523 -0.0002

ILE 523 VAL 524 -0.0002

VAL 524 PHE 525 0.0000

PHE 525 GLY 526 0.0003

GLY 526 ILE 527 -0.0001

ILE 527 TYR 528 -0.0001

TYR 528 MET 529 -0.0073

MET 529 LEU 530 0.0001

LEU 530 VAL 531 0.0003

VAL 531 SER 532 0.0000

SER 532 VAL 533 -0.0001

VAL 533 VAL 534 -0.0000

VAL 534 VAL 535 0.0003

VAL 535 LEU 536 -0.0004

LEU 536 ILE 537 -0.0283

ILE 537 ASN 538 -0.0001

ASN 538 LEU 539 -0.0003

LEU 539 LEU 540 0.0004

LEU 540 ILE 541 -0.0003

ILE 541 ALA 542 0.0003

ALA 542 MET 543 0.0004

MET 543 MET 544 0.0002

MET 544 SER 545 0.0162

SER 545 ASP 546 -0.0004

ASP 546 THR 547 0.0002

THR 547 TYR 548 -0.0001

TYR 548 GLN 549 -0.0001

GLN 549 ARG 550 0.0002

ARG 550 ILE 551 -0.0000

ILE 551 GLN 552 -0.0002

GLN 552 ALA 553 -0.0162

ALA 553 GLN 554 -0.0001

GLN 554 SER 555 -0.0005

SER 555 ASP 556 -0.0001

ASP 556 ILE 557 -0.0001

ILE 557 GLU 558 0.0003

GLU 558 TRP 559 -0.0000

TRP 559 LYS 560 0.0004

LYS 560 PHE 561 -0.0131

PHE 561 GLY 562 0.0004

GLY 562 LEU 563 -0.0003

LEU 563 SER 564 -0.0002

SER 564 LYS 565 -0.0002

LYS 565 LEU 566 0.0002

LEU 566 ILE 567 0.0003

ILE 567 ARG 568 -0.0001

ARG 568 ASN 569 0.0044

ASN 569 MET 570 0.0001

MET 570 HIS 571 0.0002

HIS 571 ARG 572 0.0001

ARG 572 THR 573 -0.0001

THR 573 THR 574 0.0001

THR 574 THR 575 0.0001

THR 575 ALA 576 0.0000

ALA 576 PRO 577 0.0469

PRO 577 SER 578 0.0002

SER 578 PRO 579 0.0006

PRO 579 LEU 580 0.0001

LEU 580 ASN 581 0.0002

ASN 581 LEU 582 0.0001

LEU 582 VAL 583 -0.0002

VAL 583 THR 584 0.0003

THR 584 THR 585 -0.0329

THR 585 TRP 586 0.0003

TRP 586 PHE 587 0.0003

PHE 587 MET 588 0.0001

MET 588 TRP 589 -0.0000

TRP 589 ARG 657 -0.0088

ARG 657 ILE 658 0.0002

ILE 658 GLU 659 -0.0002

GLU 659 ASN 660 -0.0001

ASN 660 VAL 661 -0.0002

VAL 661 ALA 662 0.0001

ALA 662 ASP 663 0.0000

ASP 663 TRP 664 -0.0001

TRP 664 GLU 665 -0.0554

GLU 665 ALA 666 -0.0000

ALA 666 ILE 667 0.0000

ILE 667 ALA 668 0.0000

ALA 668 LYS 669 -0.0001

LYS 669 LYS 670 -0.0002

LYS 670 TYR 671 0.0001

TYR 671 ARG 672 -0.0001

ARG 672 ALA 673 0.0337

ALA 673 LEU 674 0.0003

LEU 674 VAL 675 -0.0001

VAL 675 GLY 676 -0.0001

GLY 676 ASP 677 0.0002

ASP 677 GLU 678 0.0002

GLU 678 GLU 679 0.0002

GLU 679 GLY 680 0.0002

GLY 680 GLY 681 0.3429

GLY 681 SER 682 -0.0000

SER 682 LEU 683 0.0003

LEU 683 LYS 684 0.0001

LYS 684 ASP 685 0.0000

ASP 685 SER 686 0.0003

SER 686 ASP 687 -0.0000

ASP 687 ALA 688 -0.0001

ALA 688 GLU 689 -0.1072

GLU 689 SER 690 -0.0003

SER 690 GLY 691 0.0001

GLY 691 SER 692 0.0000

SER 692 GLN 693 0.0001

GLN 693 GLU 694 -0.0001

GLU 694 GLY 695 0.0000

GLY 695 SER 696 0.0001

SER 696 GLY 697 -0.3016

GLY 697 GLY 698 0.0001

GLY 698 GLN 699 -0.0001

GLN 699 GLN 700 0.0000

GLN 700 PRO 701 0.0000

PRO 701 PRO 702 -0.0000

PRO 702 ALA 703 -0.0000

ALA 703 GLN 704 0.0001

GLN 704 VAL 705 0.0888

VAL 705 GLY 706 -0.0001

GLY 706 ARG 707 -0.0001

ARG 707 ARG 708 -0.0002

ARG 708 ALA 709 0.0001

ALA 709 ILE 710 -0.0000

ILE 710 LYS 711 -0.0000

LYS 711 ALA 712 -0.0004

ALA 712 THR 713 0.2081

THR 713 LEU 714 0.0000

LEU 714 ALA 715 0.0001

ALA 715 ASP 716 0.0001

ASP 716 THR 717 -0.0002

THR 717 THR 718 0.0000

THR 718 LYS 719 0.0000

LYS 719 MET 1 -0.0346

MET 1 SER 2 -0.0001

SER 2 GLN 3 -0.0002

GLN 3 PRO 4 -0.0003

PRO 4 ARG 5 -0.0000

ARG 5 GLY 6 -0.0001

GLY 6 GLY 7 -0.0003

GLY 7 ARG 8 -0.0000

ARG 8 GLY 9 -0.0804

GLY 9 GLY 10 0.0004

GLY 10 GLY 11 -0.0002

GLY 11 ARG 12 -0.0000

ARG 12 GLY 13 0.0002

GLY 13 GLY 14 -0.0001

GLY 14 GLY 15 -0.0000

GLY 15 VAL 16 -0.0003

VAL 16 GLY 17 -0.2094

GLY 17 ARG 18 0.0000

ARG 18 LYS 19 -0.0001

LYS 19 THR 20 0.0001

THR 20 PRO 21 0.0001

PRO 21 SER 22 -0.0004

SER 22 SER 23 -0.0000

SER 23 LEU 24 0.0001

LEU 24 THR 25 -0.0494

THR 25 GLY 26 0.0004

GLY 26 PRO 27 -0.0003

PRO 27 PRO 28 0.0000

PRO 28 ASP 29 -0.0000

ASP 29 GLU 30 -0.0000

GLU 30 SER 31 -0.0002

SER 31 ALA 32 0.0004

ALA 32 THR 33 0.1140

THR 33 PRO 34 -0.0001

PRO 34 SER 35 -0.0001

SER 35 GLU 36 -0.0002

GLU 36 ARG 37 0.0001

ARG 37 ALA 38 0.0000

ALA 38 THR 39 0.0002

THR 39 PRO 40 -0.0003

PRO 40 ALA 41 0.1894

ALA 41 SER 42 -0.0002

SER 42 LYS 43 0.0002

LYS 43 ALA 44 0.0001

ALA 44 ASP 45 -0.0002

ASP 45 SER 46 0.0001

SER 46 ASP 47 0.0001

ASP 47 PRO 48 -0.0003

PRO 48 LYS 49 -0.0185

LYS 49 ASP 50 -0.0000

ASP 50 ASP 51 0.0000

ASP 51 SER 52 -0.0000

SER 52 SER 53 0.0000

SER 53 SER 54 0.0001

SER 54 ASN 55 -0.0000

ASN 55 GLY 56 0.0001

GLY 56 ASP 57 -0.5546

ASP 57 LYS 58 -0.0001

LYS 58 LYS 59 0.0000

LYS 59 ASP 60 0.0001

ASP 60 MET 61 0.0002

MET 61 ASP 62 0.0000

ASP 62 LEU 63 -0.0001

LEU 63 PHE 64 0.0001

PHE 64 PRO 65 -0.2454

PRO 65 ALA 66 -0.0000

ALA 66 PRO 67 -0.0003

PRO 67 LYS 68 -0.0001

LYS 68 PRO 69 -0.0001

PRO 69 PRO 70 -0.0001

PRO 70 SER 71 -0.0000

SER 71 ALA 72 0.0000

ALA 72 GLY 73 0.4171

GLY 73 ALA 74 0.0001

ALA 74 SER 75 -0.0000

SER 75 ILE 76 0.0002

ILE 76 ARG 77 0.0000

ARG 77 ASP 78 0.0002

ASP 78 THR 79 -0.0000

THR 79 ALA 80 -0.0001

ALA 80 ASN 81 0.0539

ASN 81 LYS 82 0.0000

LYS 82 VAL 83 0.0002

VAL 83 LEU 84 -0.0001

LEU 84 GLY 85 0.0000

GLY 85 LEU 86 0.0003

LEU 86 ALA 87 -0.0002

ALA 87 MET 88 0.0001

MET 88 LYS 89 -0.0050

LYS 89 SER 90 -0.0003

SER 90 GLU 91 0.0003

GLU 91 TRP 92 -0.0002

TRP 92 THR 93 0.0001

THR 93 PRO 94 -0.0001

PRO 94 ILE 95 -0.0001

ILE 95 GLU 96 0.0003

GLU 96 ALA 97 -0.0373

ALA 97 GLU 98 -0.0002

GLU 98 LEU 99 -0.0002

LEU 99 LYS 100 0.0004

LYS 100 LYS 101 -0.0002

LYS 101 LEU 102 -0.0004

LEU 102 GLU 103 0.0002

GLU 103 LYS 104 0.0000

LYS 104 TYR 105 0.0029

TYR 105 VAL 106 -0.0002

VAL 106 ALA 107 0.0003

ALA 107 ASN 108 -0.0001

ASN 108 VAL 109 0.0003

VAL 109 GLY 110 -0.0002

GLY 110 GLU 111 -0.0001

GLU 111 ASP 112 -0.0001

ASP 112 GLY 113 0.1632

GLY 113 ASN 114 0.0002

ASN 114 HIS 115 0.0002

HIS 115 ILE 116 0.0002

ILE 116 PRO 117 -0.0001

PRO 117 LEU 118 0.0002

LEU 118 ALA 119 0.0001

ALA 119 GLY 120 0.0001

GLY 120 VAL 121 0.1275

VAL 121 HIS 122 0.0003

HIS 122 ASP 123 -0.0003

ASP 123 MET 124 -0.0003

MET 124 ASN 125 -0.0002

ASN 125 LEU 126 0.0001

LEU 126 MET 127 -0.0003

MET 127 GLU 128 0.0002

GLU 128 ASP 129 -0.0653

ASP 129 LYS 130 -0.0002

LYS 130 ARG 131 -0.0001

ARG 131 PHE 132 0.0004

PHE 132 VAL 133 -0.0003

VAL 133 TYR 134 -0.0003

TYR 134 ASN 135 0.0001

ASN 135 LEU 136 0.0002

LEU 136 MET 137 0.0048

MET 137 VAL 138 0.0002

VAL 138 VAL 139 0.0002

VAL 139 SER 140 -0.0003

SER 140 LYS 141 -0.0001

LYS 141 ASN 142 -0.0000

ASN 142 HIS 143 0.0000

HIS 143 ASN 144 0.0000

ASN 144 ASN 145 -0.0215

ASN 145 LYS 146 0.0002

LYS 146 PRO 147 -0.0002

PRO 147 ILE 148 0.0001

ILE 148 GLN 149 0.0000

GLN 149 GLU 150 0.0002

GLU 150 PHE 151 -0.0003

PHE 151 VAL 152 -0.0000

VAL 152 LEU 153 0.0116

LEU 153 VAL 154 0.0001

VAL 154 SER 155 -0.0004

SER 155 PRO 156 0.0000

PRO 156 ALA 157 0.0005

ALA 157 PRO 158 -0.0002

PRO 158 VAL 159 -0.0002

VAL 159 ASP 160 0.0000

ASP 160 THR 161 -0.0185

THR 161 ALA 162 0.0001

ALA 162 ALA 163 0.0001

ALA 163 LYS 164 -0.0001

LYS 164 LEU 165 0.0002

LEU 165 SER 166 -0.0001

SER 166 ASN 167 0.0002

ASN 167 ILE 168 0.0003

ILE 168 TYR 169 -0.0299

TYR 169 ILE 170 0.0000

ILE 170 VAL 171 -0.0003

VAL 171 LEU 172 0.0003

LEU 172 SER 173 -0.0001

SER 173 THR 174 0.0002

THR 174 LYS 175 0.0004

LYS 175 GLU 176 -0.0001

GLU 176 LYS 177 -0.0444

LYS 177 GLU 178 0.0003

GLU 178 ARG 179 -0.0002

ARG 179 ALA 180 -0.0001

ALA 180 LYS 181 0.0003

LYS 181 ASP 182 -0.0002

ASP 182 LEU 183 0.0003

LEU 183 VAL 184 -0.0001

VAL 184 ALA 185 0.0263

ALA 185 ALA 186 -0.0001

ALA 186 GLY 187 -0.0003

GLY 187 LYS 188 0.0002

LYS 188 GLN 189 0.0001

GLN 189 CYS 190 -0.0003

CYS 190 GLU 191 0.0001

GLU 191 ALA 192 -0.0004

ALA 192 MET 193 -0.0675

MET 193 ALA 194 -0.0003

ALA 194 THR 195 -0.0002

THR 195 GLU 196 0.0002

GLU 196 LEU 197 -0.0000

LEU 197 LEU 198 -0.0001

LEU 198 ALA 199 -0.0002

ALA 199 LEU 200 -0.0001

LEU 200 ALA 201 0.0130

ALA 201 ALA 202 0.0003

ALA 202 GLY 203 -0.0002

GLY 203 SER 204 0.0003

SER 204 ASP 205 -0.0002

ASP 205 SER 206 -0.0000

SER 206 ALA 207 -0.0000

ALA 207 GLY 208 -0.0000

GLY 208 LYS 209 0.0030

LYS 209 ILE 210 -0.0002

ILE 210 LEU 211 0.0001

LEU 211 GLN 212 0.0001

GLN 212 ALA 213 -0.0004

ALA 213 THR 214 -0.0000

THR 214 ASP 215 -0.0002

ASP 215 LYS 216 0.0004

LYS 216 ARG 217 -0.0287

ARG 217 ASN 218 0.0002

ASN 218 VAL 219 -0.0002

VAL 219 GLU 220 0.0004

GLU 220 PHE 221 -0.0002

PHE 221 LEU 222 -0.0002

LEU 222 ASP 223 0.0004

ASP 223 VAL 224 0.0003

VAL 224 LEU 225 0.0487

LEU 225 ILE 226 0.0004

ILE 226 GLU 227 0.0002

GLU 227 ASN 228 0.0002

ASN 228 GLU 229 -0.0003

GLU 229 GLN 230 0.0001

GLN 230 LYS 231 -0.0002

LYS 231 GLU 232 -0.0000

GLU 232 VAL 233 -0.0246

VAL 233 ILE 234 0.0002

ILE 234 ALA 235 -0.0002

ALA 235 HIS 236 -0.0000

HIS 236 THR 237 -0.0004

THR 237 VAL 238 0.0001

VAL 238 VAL 239 0.0001

VAL 239 GLN 240 0.0002

GLN 240 ARG 241 -0.0182

ARG 241 TYR 242 0.0001

TYR 242 LEU 243 -0.0004

LEU 243 GLN 244 0.0001

GLN 244 GLU 245 0.0004

GLU 245 LEU 246 -0.0001

LEU 246 TRP 247 0.0001

TRP 247 HIS 248 -0.0001

HIS 248 GLY 249 0.0484

GLY 249 SER 250 0.0001

SER 250 LEU 251 0.0001

LEU 251 THR 252 -0.0001

THR 252 TRP 253 0.0002

TRP 253 ALA 254 -0.0003

ALA 254 SER 255 0.0000

SER 255 TRP 256 -0.0004

TRP 256 LYS 257 0.0071

LYS 257 ILE 258 0.0001

ILE 258 LEU 259 0.0000

LEU 259 LEU 260 0.0001

LEU 260 LEU 261 -0.0000

LEU 261 LEU 262 0.0001

LEU 262 VAL 263 0.0001

VAL 263 ALA 264 -0.0001

ALA 264 PHE 265 -0.0139

PHE 265 ILE 266 -0.0002

ILE 266 VAL 267 -0.0002

VAL 267 CYS 268 -0.0000

CYS 268 PRO 269 0.0001

PRO 269 PRO 270 0.0001

PRO 270 VAL 271 0.0002

VAL 271 TRP 272 -0.0001

TRP 272 ILE 273 0.0036

ILE 273 GLY 274 -0.0000

GLY 274 PHE 275 -0.0001

PHE 275 THR 276 0.0000

THR 276 PHE 277 0.0000

PHE 277 PRO 278 -0.0000

PRO 278 MET 279 -0.0003

MET 279 GLY 280 0.0002

GLY 280 HIS 281 0.0362

HIS 281 LYS 282 0.0003

LYS 282 PHE 283 -0.0004

PHE 283 ASN 284 0.0002

ASN 284 LYS 285 -0.0003

LYS 285 VAL 286 0.0000

VAL 286 PRO 287 -0.0001

PRO 287 ILE 288 0.0001

ILE 288 ILE 289 0.0413

ILE 289 LYS 290 0.0000

LYS 290 PHE 291 -0.0001

PHE 291 MET 292 -0.0003

MET 292 SER 293 -0.0002

SER 293 TYR 294 -0.0001

TYR 294 LEU 295 -0.0003

LEU 295 THR 296 0.0001

THR 296 SER 297 0.0259

SER 297 HIS 298 0.0004

HIS 298 ILE 299 0.0001

ILE 299 TYR 300 0.0000

TYR 300 LEU 301 0.0004

LEU 301 MET 302 -0.0002

MET 302 ILE 303 -0.0000

ILE 303 HIS 304 -0.0001

HIS 304 LEU 305 -0.0494

LEU 305 SER 306 -0.0001

SER 306 ILE 307 -0.0001

ILE 307 VAL 308 -0.0001

VAL 308 GLY 309 -0.0001

GLY 309 ILE 310 -0.0002

ILE 310 THR 311 0.0000

THR 311 PRO 312 0.0002

PRO 312 ILE 313 -0.0284

ILE 313 TYR 314 0.0000

TYR 314 PRO 315 -0.0002

PRO 315 VAL 316 0.0005

VAL 316 LEU 317 -0.0002

LEU 317 ARG 318 0.0002

ARG 318 LEU 319 -0.0004

LEU 319 SER 320 0.0002

SER 320 LEU 321 -0.0125

LEU 321 VAL 322 -0.0000

VAL 322 PRO 323 -0.0001

PRO 323 TYR 324 -0.0000

TYR 324 TRP 325 -0.0000

TRP 325 TYR 326 0.0002

TYR 326 GLU 327 -0.0001

GLU 327 VAL 328 -0.0002

VAL 328 GLY 329 -0.0210

GLY 329 LEU 330 0.0000

LEU 330 LEU 331 -0.0001

LEU 331 ILE 332 -0.0003

ILE 332 TRP 333 -0.0002

TRP 333 LEU 334 0.0000

LEU 334 SER 335 -0.0001

SER 335 GLY 336 0.0000

GLY 336 LEU 337 -0.0149

LEU 337 LEU 338 0.0000

LEU 338 LEU 339 0.0003

LEU 339 PHE 340 -0.0003

PHE 340 GLU 341 -0.0000

GLU 341 LEU 342 -0.0001

LEU 342 THR 343 -0.0002

THR 343 ASN 344 -0.0001

ASN 344 PRO 345 0.0033

PRO 345 SER 346 0.0004

SER 346 ASP 347 -0.0002

ASP 347 LYS 348 0.0000

LYS 348 SER 349 -0.0003

SER 349 GLY 350 -0.0000

GLY 350 LEU 351 0.0004

LEU 351 GLY 352 -0.0000

GLY 352 SER 353 0.0152

SER 353 ILE 354 -0.0002

ILE 354 LYS 355 -0.0001

LYS 355 VAL 356 -0.0002

VAL 356 LEU 357 0.0001

LEU 357 VAL 358 0.0003

VAL 358 LEU 359 -0.0001

LEU 359 LEU 360 -0.0003

LEU 360 LEU 361 0.0274

LEU 361 GLY 362 -0.0001

GLY 362 MET 363 -0.0001

MET 363 ALA 364 0.0002

ALA 364 GLY 365 -0.0001

GLY 365 VAL 366 -0.0001

VAL 366 GLY 367 0.0001

GLY 367 VAL 368 0.0001

VAL 368 HIS 369 0.0124

HIS 369 VAL 370 0.0003

VAL 370 SER 371 -0.0002

SER 371 ALA 372 -0.0002

ALA 372 PHE 373 -0.0003

PHE 373 LEU 374 0.0003

LEU 374 PHE 375 0.0001

PHE 375 VAL 376 -0.0004

VAL 376 SER 377 0.0193

SER 377 LYS 378 0.0003

LYS 378 GLU 379 0.0003

GLU 379 TYR 380 -0.0001

TYR 380 TRP 381 0.0002

TRP 381 PRO 382 0.0001

PRO 382 THR 383 0.0004

THR 383 LEU 384 0.0000

LEU 384 VAL 385 0.0127

VAL 385 TYR 386 -0.0001

TYR 386 CYS 387 0.0001

CYS 387 ARG 388 -0.0003

ARG 388 ASN 389 0.0001

ASN 389 GLN 390 0.0004

GLN 390 CYS 391 -0.0002

CYS 391 PHE 392 0.0001

PHE 392 ALA 393 0.0135

ALA 393 LEU 394 -0.0001

LEU 394 ALA 395 0.0002

ALA 395 PHE 396 -0.0002

PHE 396 LEU 397 0.0002

LEU 397 LEU 398 0.0001

LEU 398 ALA 399 0.0001

ALA 399 CYS 400 -0.0000

CYS 400 VAL 401 0.0188

VAL 401 GLN 402 -0.0004

GLN 402 ILE 403 0.0003

ILE 403 LEU 404 0.0001

LEU 404 ASP 405 0.0000

ASP 405 PHE 406 0.0002

PHE 406 LEU 407 0.0003

LEU 407 SER 408 -0.0000

SER 408 PHE 409 0.0078

PHE 409 HIS 410 -0.0000

HIS 410 HIS 411 -0.0001

HIS 411 LEU 412 0.0001

LEU 412 PHE 413 -0.0004

PHE 413 GLY 414 0.0002

GLY 414 PRO 415 0.0002

PRO 415 TRP 416 0.0004

TRP 416 ALA 417 -0.0290

ALA 417 ILE 418 0.0003

ILE 418 ILE 419 0.0001

ILE 419 ILE 420 -0.0001

ILE 420 GLY 421 0.0003

GLY 421 ASP 422 -0.0003

ASP 422 LEU 423 0.0001

LEU 423 LEU 424 0.0001

LEU 424 LYS 425 -0.0833

LYS 425 ASP 426 0.0001

ASP 426 LEU 427 -0.0001

LEU 427 ALA 428 -0.0003

ALA 428 ARG 429 -0.0002

ARG 429 PHE 430 0.0000

PHE 430 LEU 431 -0.0002

LEU 431 ALA 432 -0.0001

ALA 432 VAL 433 -0.0400

VAL 433 LEU 434 0.0001

LEU 434 ALA 435 -0.0001

ALA 435 ILE 436 -0.0000

ILE 436 PHE 437 -0.0004

PHE 437 VAL 438 -0.0001

VAL 438 PHE 439 -0.0002

PHE 439 GLY 440 0.0002

GLY 440 PHE 441 -0.0093

PHE 441 SER 442 0.0000

SER 442 MET 443 -0.0002

MET 443 HIS 444 -0.0004

HIS 444 ILE 445 0.0002

ILE 445 VAL 446 0.0004

VAL 446 ALA 447 0.0002

ALA 447 LEU 448 -0.0000

LEU 448 ASN 449 0.0037

ASN 449 GLN 450 -0.0000

GLN 450 SER 451 0.0001

SER 451 PHE 452 -0.0000

PHE 452 ALA 453 -0.0000

ALA 453 ASN 454 -0.0003

ASN 454 PHE 455 0.0002

PHE 455 SER 456 -0.0002

SER 456 PRO 457 0.0127

PRO 457 GLU 458 -0.0000

GLU 458 ASP 459 -0.0001

ASP 459 LEU 460 -0.0002

LEU 460 ARG 461 0.0005

ARG 461 SER 462 -0.0001

SER 462 PHE 463 -0.0003

PHE 463 GLU 464 -0.0001

GLU 464 LYS 465 0.0150

LYS 465 LYS 466 -0.0001

LYS 466 ASN 467 -0.0001

ASN 467 ARG 468 -0.0001

ARG 468 ASN 469 -0.0004

ASN 469 ARG 470 0.0002

ARG 470 GLY 471 0.0001

GLY 471 TYR 472 -0.0000

TYR 472 PHE 473 -0.0212

PHE 473 SER 474 -0.0004

SER 474 ASP 475 -0.0003

ASP 475 VAL 476 -0.0000

VAL 476 ARG 477 -0.0002

ARG 477 MET 478 0.0000

MET 478 HIS 479 0.0003

HIS 479 PRO 480 0.0003

PRO 480 ILE 481 -0.2001

ILE 481 ASN 482 0.0001

ASN 482 SER 483 -0.0004

SER 483 PHE 484 0.0000

PHE 484 GLU 485 -0.0001

GLU 485 LEU 486 -0.0004

LEU 486 LEU 487 0.0003

LEU 487 PHE 488 0.0001

PHE 488 PHE 489 0.0052

PHE 489 ALA 490 0.0002

ALA 490 VAL 491 -0.0001

VAL 491 PHE 492 0.0002

PHE 492 GLY 493 -0.0002

GLY 493 GLN 494 -0.0000

GLN 494 THR 495 -0.0002

THR 495 THR 496 0.0000

THR 496 THR 497 0.0937

THR 497 GLU 498 0.0001

GLU 498 GLN 499 0.0001

GLN 499 THR 500 -0.0000

THR 500 GLN 501 -0.0003

GLN 501 VAL 502 0.0004

VAL 502 ASP 503 -0.0002

ASP 503 LYS 504 -0.0002

LYS 504 ILE 505 -0.0203

ILE 505 LYS 506 0.0002

LYS 506 ASN 507 -0.0000

ASN 507 VAL 508 0.0002

VAL 508 ALA 509 0.0002

ALA 509 THR 510 -0.0001

THR 510 PRO 511 0.0000

PRO 511 THR 512 -0.0001

THR 512 GLN 513 0.0120

GLN 513 PRO 514 -0.0002

PRO 514 TYR 515 0.0002

TYR 515 TRP 516 0.0006

TRP 516 VAL 517 0.0003

VAL 517 GLU 518 -0.0000

GLU 518 TYR 519 0.0000

TYR 519 LEU 520 0.0005

LEU 520 PHE 521 -0.0264

PHE 521 LYS 522 0.0002

LYS 522 ILE 523 -0.0003

ILE 523 VAL 524 0.0001

VAL 524 PHE 525 -0.0001

PHE 525 GLY 526 0.0000

GLY 526 ILE 527 -0.0001

ILE 527 TYR 528 -0.0001

TYR 528 MET 529 0.0059

MET 529 LEU 530 0.0002

LEU 530 VAL 531 0.0000

VAL 531 SER 532 0.0004

SER 532 VAL 533 0.0002

VAL 533 VAL 534 -0.0002

VAL 534 VAL 535 -0.0001

VAL 535 LEU 536 0.0001

LEU 536 ILE 537 0.0271

ILE 537 ASN 538 0.0001

ASN 538 LEU 539 0.0001

LEU 539 LEU 540 -0.0000

LEU 540 ILE 541 0.0000

ILE 541 ALA 542 0.0004

ALA 542 MET 543 0.0001

MET 543 MET 544 -0.0002

MET 544 SER 545 -0.0204

SER 545 ASP 546 0.0000

ASP 546 THR 547 0.0005

THR 547 TYR 548 0.0001

TYR 548 GLN 549 0.0000

GLN 549 ARG 550 0.0001

ARG 550 ILE 551 -0.0003

ILE 551 GLN 552 0.0000

GLN 552 ALA 553 0.0518

ALA 553 GLN 554 0.0001

GLN 554 SER 555 -0.0000

SER 555 ASP 556 0.0002

ASP 556 ILE 557 -0.0001

ILE 557 GLU 558 -0.0002

GLU 558 TRP 559 0.0004

TRP 559 LYS 560 -0.0001

LYS 560 PHE 561 0.0036

PHE 561 GLY 562 0.0002

GLY 562 LEU 563 0.0000

LEU 563 SER 564 -0.0003

SER 564 LYS 565 -0.0001

LYS 565 LEU 566 0.0000

LEU 566 ILE 567 0.0003

ILE 567 ARG 568 -0.0005

ARG 568 ASN 569 -0.0408

ASN 569 MET 570 0.0003

MET 570 HIS 571 -0.0005

HIS 571 ARG 572 -0.0002

ARG 572 THR 573 0.0002

THR 573 THR 574 0.0000

THR 574 THR 575 0.0002

THR 575 ALA 576 0.0003

ALA 576 PRO 577 -0.0787

PRO 577 SER 578 0.0000

SER 578 PRO 579 -0.0000

PRO 579 LEU 580 0.0000

LEU 580 ASN 581 -0.0002

ASN 581 LEU 582 0.0001

LEU 582 VAL 583 0.0004

VAL 583 THR 584 0.0000

THR 584 THR 585 0.0384

THR 585 TRP 586 0.0000

TRP 586 PHE 587 -0.0001

PHE 587 MET 588 0.0001

MET 588 TRP 589 0.0003

TRP 589 ARG 657 -0.0575

ARG 657 ILE 658 -0.0001

ILE 658 GLU 659 0.0002

GLU 659 ASN 660 -0.0002

ASN 660 VAL 661 0.0001

VAL 661 ALA 662 -0.0001

ALA 662 ASP 663 0.0003

ASP 663 TRP 664 0.0002

TRP 664 GLU 665 -0.0027

GLU 665 ALA 666 0.0001

ALA 666 ILE 667 -0.0000

ILE 667 ALA 668 0.0003

ALA 668 LYS 669 0.0003

LYS 669 LYS 670 -0.0003

LYS 670 TYR 671 0.0002

TYR 671 ARG 672 -0.0006

ARG 672 ALA 673 0.0629

ALA 673 LEU 674 -0.0001

LEU 674 VAL 675 -0.0002

VAL 675 GLY 676 -0.0002

GLY 676 ASP 677 -0.0002

ASP 677 GLU 678 -0.0000

GLU 678 GLU 679 0.0002

GLU 679 GLY 680 0.0001

GLY 680 GLY 681 0.3254

GLY 681 SER 682 -0.0001

SER 682 LEU 683 -0.0002

LEU 683 LYS 684 0.0002

LYS 684 ASP 685 0.0000

ASP 685 SER 686 0.0001

SER 686 ASP 687 -0.0001

ASP 687 ALA 688 0.0002

ALA 688 GLU 689 0.1757

GLU 689 SER 690 -0.0002

SER 690 GLY 691 0.0001

GLY 691 SER 692 0.0000

SER 692 GLN 693 -0.0001

GLN 693 GLU 694 0.0002

GLU 694 GLY 695 -0.0001

GLY 695 SER 696 0.0000

SER 696 GLY 697 0.3158

GLY 697 GLY 698 -0.0001

GLY 698 GLN 699 0.0000

GLN 699 GLN 700 -0.0002

GLN 700 PRO 701 -0.0001

PRO 701 PRO 702 0.0000

PRO 702 ALA 703 0.0001

ALA 703 GLN 704 0.0001

GLN 704 VAL 705 -0.0947

VAL 705 GLY 706 -0.0002

GLY 706 ARG 707 -0.0000

ARG 707 ARG 708 -0.0004

ARG 708 ALA 709 -0.0000

ALA 709 ILE 710 -0.0000

ILE 710 LYS 711 0.0000

LYS 711 ALA 712 -0.0001

ALA 712 THR 713 -0.2790

THR 713 LEU 714 -0.0003

LEU 714 ALA 715 -0.0004

ALA 715 ASP 716 0.0000

ASP 716 THR 717 -0.0001

THR 717 THR 718 0.0003

THR 718 LYS 719 0.0003

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.

Should you encounter any unexpected behaviour, please let us know. elNémo has been relocated. **Some cleaning from time to time** Sorry for the inconvenience.

*** dar29 ***

CA strain for 2607160252271657563

--- normal mode 103 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* dar29 *