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* 6bf8_closed *

CA distance fluctuations for 2609040146391662543

--- normal mode 7 ---

This matrix displays the maximum distance fluctuations between all pairs of CA atoms and between the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Distance increases are plotted in blue and decreases in red for the strongest 10% of the residue pair distance changes. Every pixel corresponds to a single residue. Grey lines are drawn every 10 residues, yellow lines every 100 residues (counting from the upper left corner).

The following table indicates for every residue the two corresponding residues with the strongest CA distance fluctuations.

[HELP on distance fluctuations]

GD ok

largest increase ref largest decrease
ASP 1184 0.05 ILE 966 -0.16 LYS 1485

GLU 1611 0.03 LYS 967 -0.15 LYS 1485

GLU 1611 0.04 ARG 968 -0.15 LYS 1485

GLU 1611 0.04 ILE 969 -0.17 LYS 1485

GLU 1611 0.05 GLY 970 -0.18 LYS 1485

ARG 1757 0.05 ASN 971 -0.18 LYS 1485

ARG 1757 0.06 HIS 972 -0.19 LYS 1485

ARG 1757 0.07 ILE 973 -0.17 LYS 1485

ARG 1757 0.08 THR 974 -0.15 PHE 1486

ARG 1757 0.09 LYS 975 -0.19 PHE 1486

ALA 1759 0.11 SER 976 -0.19 LEU 1488

ALA 1759 0.11 PRO 977 -0.24 LEU 1488

ARG 1758 0.13 GLU 978 -0.40 LEU 1488

ASN 1841 0.11 ASP 979 -0.38 PHE 1486

ASN 1841 0.11 LYS 980 -0.44 PHE 1486

ASN 1841 0.09 ARG 981 -0.38 LYS 1485

ASN 1841 0.07 GLU 982 -0.33 LYS 1485

GLY 1755 0.06 TYR 983 -0.26 LYS 1485

GLY 1755 0.05 ARG 984 -0.23 LYS 1485

GLY 1755 0.05 GLY 985 -0.19 LYS 1485

GLU 1611 0.04 LEU 986 -0.18 LYS 1485

GLU 1611 0.04 GLU 987 -0.16 LYS 1485

THR 1187 0.04 LEU 988 -0.15 LYS 1485

THR 1187 0.04 ALA 989 -0.14 PRO 1465

GLU 1413 0.04 ASN 990 -0.14 PRO 1465

GLU 1413 0.04 GLY 991 -0.13 PRO 1465

GLU 1413 0.04 ILE 992 -0.14 PRO 1465

ARG 1606 0.04 LYS 993 -0.15 LYS 1485

GLY 1755 0.04 VAL 994 -0.17 LYS 1485

GLY 1755 0.05 LEU 995 -0.20 LYS 1485

GLY 1755 0.05 LEU 996 -0.24 LYS 1485

GLY 1755 0.06 ILE 997 -0.29 LYS 1485

ALA 1845 0.06 SER 998 -0.35 LYS 1485

ALA 1845 0.08 ASP 999 -0.43 LYS 1485

ALA 1845 0.08 PRO 1000 -0.49 LYS 1485

ALA 1845 0.10 THR 1001 -0.58 LYS 1485

ALA 1845 0.09 THR 1002 -0.44 LYS 1485

ILE 1810 0.11 ASP 1003 -0.41 PRO 1465

ILE 1810 0.10 LYS 1004 -0.33 PRO 1465

GLY 1755 0.06 SER 1005 -0.29 PRO 1465

GLY 1755 0.06 SER 1006 -0.24 PRO 1465

GLY 1755 0.05 ALA 1007 -0.21 PRO 1465

PHE 1753 0.05 ALA 1008 -0.17 PRO 1465

ILE 1751 0.04 LEU 1009 -0.15 PRO 1465

ILE 1751 0.05 ASP 1010 -0.13 PRO 1465

TRP 1414 0.05 VAL 1011 -0.12 PRO 1465

TRP 1414 0.05 HIS 1012 -0.10 PRO 1465

TRP 1414 0.06 ILE 1013 -0.09 PRO 1465

TRP 1414 0.07 GLY 1014 -0.08 ILE 1831

TRP 1414 0.09 SER 1015 -0.08 ILE 1831

TRP 1414 0.08 LEU 1016 -0.07 ILE 1831

GLU 1413 0.09 SER 1017 -0.07 ILE 1831

GLU 1413 0.11 ASP 1018 -0.08 ILE 1831

GLU 1413 0.12 PRO 1019 -0.07 ILE 1831

GLU 1413 0.15 PRO 1020 -0.07 ILE 1831

GLU 1413 0.16 ASN 1021 -0.07 ILE 1831

GLU 1413 0.15 ILE 1022 -0.08 ILE 1831

TRP 1414 0.16 ALA 1023 -0.08 ILE 1831

TRP 1414 0.12 GLY 1024 -0.09 ILE 1831

TRP 1414 0.10 LEU 1025 -0.09 ILE 1831

TRP 1414 0.08 SER 1026 -0.09 ILE 1831

TRP 1414 0.07 HIS 1027 -0.10 ILE 1831

TRP 1414 0.07 PHE 1028 -0.10 ILE 1831

GLU 1413 0.07 LEU 1029 -0.10 ILE 1831

TRP 1414 0.05 GLU 1030 -0.11 ILE 1831

GLU 1413 0.04 HIS 1031 -0.11 ILE 1831

GLU 1413 0.05 MET 1032 -0.11 ILE 1831

GLU 1413 0.05 LEU 1033 -0.12 PRO 1465

TYR 1068 0.04 PHE 1034 -0.13 PRO 1465

GLU 1413 0.04 LEU 1035 -0.12 PRO 1465

GLU 1413 0.04 GLY 1036 -0.13 PRO 1465

GLU 1413 0.04 THR 1037 -0.14 PRO 1465

GLU 1413 0.05 LYS 1038 -0.15 PRO 1465

GLU 1413 0.04 LYS 1039 -0.17 PRO 1465

GLU 1413 0.03 TYR 1040 -0.16 PRO 1465

GLU 1413 0.04 PRO 1041 -0.14 PRO 1465

GLU 1413 0.03 LYS 1042 -0.14 PRO 1465

GLU 1413 0.03 GLU 1043 -0.13 PRO 1465

LYS 1745 0.07 ASN 1044 -0.14 PRO 1465

LYS 1745 0.05 GLU 1045 -0.17 PRO 1465

LYS 1745 0.06 TYR 1046 -0.17 PRO 1465

LYS 1745 0.08 SER 1047 -0.16 PRO 1465

LYS 1745 0.07 GLN 1048 -0.17 PRO 1465

LYS 1745 0.06 PHE 1049 -0.20 PRO 1465

ASN 1740 0.07 LEU 1050 -0.20 PRO 1465

GLU 1736 0.11 SER 1051 -0.19 TYR 1466

PHE 1785 0.06 GLU 1052 -0.21 TYR 1466

GLU 1736 0.06 HIS 1053 -0.24 TYR 1466

GLU 1736 0.11 ALA 1054 -0.25 TYR 1466

GLU 1736 0.11 GLY 1055 -0.22 TYR 1466

GLU 1736 0.12 SER 1056 -0.18 TYR 1466

THR 1744 0.09 SER 1057 -0.16 PRO 1465

THR 1744 0.09 ASN 1058 -0.13 ILE 1831

THR 1744 0.07 ALA 1059 -0.12 ILE 1831

ILE 1751 0.07 PHE 1060 -0.11 ILE 1831

ILE 1751 0.05 THR 1061 -0.10 ILE 1831

MET 1602 0.06 SER 1062 -0.09 ILE 1831

TRP 1414 0.06 GLY 1063 -0.08 ILE 1831

TRP 1414 0.05 GLU 1064 -0.07 ILE 1831

TRP 1414 0.05 HIS 1065 -0.09 PRO 1465

TRP 1414 0.05 THR 1066 -0.10 PRO 1465

ILE 1751 0.05 ASN 1067 -0.11 PRO 1465

THR 1744 0.06 TYR 1068 -0.14 PRO 1465

THR 1744 0.06 TYR 1069 -0.16 PRO 1465

THR 1744 0.07 PHE 1070 -0.19 PRO 1465

GLU 1736 0.07 ASP 1071 -0.22 PRO 1465

GLU 1736 0.07 VAL 1072 -0.26 PRO 1465

GLU 1736 0.06 SER 1073 -0.31 PRO 1465

GLN 1806 0.06 HIS 1074 -0.37 PRO 1465

LEU 1786 0.04 GLU 1075 -0.34 PRO 1465

LYS 1745 0.04 HIS 1076 -0.29 PRO 1465

THR 1744 0.04 LEU 1077 -0.27 PRO 1465

LYS 1745 0.03 GLU 1078 -0.25 PRO 1465

LYS 1745 0.04 GLY 1079 -0.24 PRO 1465

LYS 1745 0.05 ALA 1080 -0.23 PRO 1465

THR 1744 0.04 LEU 1081 -0.22 PRO 1465

LYS 1745 0.03 ASP 1082 -0.21 PRO 1465

LYS 1745 0.04 ARG 1083 -0.19 PRO 1465

THR 1744 0.04 PHE 1084 -0.19 PRO 1465

GLU 1413 0.03 ALA 1085 -0.18 PRO 1465

GLU 1413 0.04 GLN 1086 -0.17 PRO 1465

GLU 1413 0.04 PHE 1087 -0.16 PRO 1465

GLU 1413 0.04 PHE 1088 -0.15 PRO 1465

GLU 1413 0.04 LEU 1089 -0.15 PRO 1465

GLU 1413 0.05 SER 1090 -0.14 PRO 1465

GLU 1413 0.05 PRO 1091 -0.13 PRO 1465

GLU 1413 0.06 LEU 1092 -0.12 PRO 1465

GLU 1413 0.06 PHE 1093 -0.11 PRO 1465

GLU 1413 0.06 ASP 1094 -0.12 ASN 1898

GLU 1413 0.07 GLU 1095 -0.14 ASN 1898

GLU 1413 0.05 SER 1096 -0.14 ASN 1898

GLU 1413 0.05 ALA 1097 -0.11 ASN 1898

GLU 1413 0.07 LYS 1098 -0.10 ASN 1898

GLU 1413 0.06 ASP 1099 -0.12 ASN 1898

ASN 1706 0.04 ARG 1100 -0.11 LEU 1899

GLU 1413 0.05 GLU 1101 -0.10 ILE 1831

GLU 1413 0.06 VAL 1102 -0.10 ILE 1831

ASN 1706 0.06 ASN 1103 -0.10 ILE 1831

GLY 1534 0.06 ALA 1104 -0.11 ILE 1831

GLY 1534 0.06 VAL 1105 -0.11 ILE 1831

GLY 1534 0.07 ASP 1106 -0.10 ILE 1831

GLY 1534 0.08 SER 1107 -0.11 ILE 1831

GLY 1534 0.08 GLU 1108 -0.12 ILE 1831

GLY 1534 0.08 HIS 1109 -0.11 ILE 1831

SER 1536 0.09 GLU 1110 -0.11 ILE 1831

SER 1536 0.10 LYS 1111 -0.13 ILE 1831

GLY 1534 0.10 ASN 1112 -0.13 ILE 1831

GLY 1534 0.09 VAL 1113 -0.13 ILE 1831

SER 1536 0.09 MET 1114 -0.14 ILE 1831

SER 1536 0.10 ASN 1115 -0.15 ILE 1831

SER 1536 0.10 ASP 1116 -0.15 ILE 1831

SER 1536 0.11 ALA 1117 -0.14 ILE 1831

GLY 1534 0.10 TRP 1118 -0.12 ILE 1831

GLY 1534 0.09 ARG 1119 -0.12 ILE 1831

ASN 1295 0.09 LEU 1120 -0.12 ILE 1831

LYS 1283 0.11 PHE 1121 -0.11 ILE 1831

LYS 1283 0.09 GLN 1122 -0.10 ILE 1831

LEU 1532 0.08 LEU 1123 -0.10 ILE 1831

THR 1235 0.09 GLU 1124 -0.10 ILE 1831

PHE 1291 0.08 LYS 1125 -0.09 ILE 1831

GLU 1412 0.08 ALA 1126 -0.09 ILE 1831

TYR 1221 0.08 THR 1127 -0.09 ILE 1831

ARG 1396 0.06 GLY 1128 -0.08 ILE 1831

ARG 1410 0.06 ASN 1129 -0.08 ILE 1831

ARG 1410 0.09 PRO 1130 -0.08 ILE 1831

PRO 1020 0.08 LYS 1131 -0.07 ILE 1831

ARG 1410 0.06 HIS 1132 -0.07 ILE 1831

GLU 1413 0.07 PRO 1133 -0.07 ILE 1831

GLU 1413 0.06 PHE 1134 -0.08 ILE 1831

GLU 1412 0.08 SER 1135 -0.08 ILE 1831

TRP 1414 0.12 LYS 1136 -0.08 ILE 1831

TRP 1414 0.16 PHE 1137 -0.09 ILE 1831

TRP 1414 0.11 GLY 1138 -0.09 ILE 1831

TRP 1414 0.10 THR 1139 -0.10 ILE 1831

TRP 1414 0.14 GLY 1140 -0.09 ILE 1831

GLY 1416 0.09 ASN 1141 -0.09 ILE 1831

GLU 1413 0.09 LYS 1142 -0.09 ILE 1831

GLU 1413 0.13 TYR 1143 -0.08 ILE 1831

GLU 1413 0.18 THR 1144 -0.08 ILE 1831

GLU 1413 0.13 LEU 1145 -0.09 ILE 1831

GLU 1413 0.11 GLU 1146 -0.10 ILE 1897

GLU 1413 0.12 THR 1147 -0.10 ILE 1897

GLU 1413 0.16 ARG 1148 -0.09 ILE 1897

GLU 1413 0.14 PRO 1149 -0.10 ILE 1897

GLU 1413 0.12 ASN 1150 -0.11 ILE 1897

GLU 1413 0.13 GLN 1151 -0.10 ILE 1897

GLU 1413 0.13 GLU 1152 -0.10 ILE 1897

GLU 1413 0.12 GLY 1153 -0.11 ILE 1897

GLU 1413 0.12 ILE 1154 -0.10 ILE 1897

GLU 1413 0.11 ASP 1155 -0.11 ILE 1897

GLU 1413 0.10 VAL 1156 -0.10 ILE 1897

GLU 1413 0.09 ARG 1157 -0.10 ASN 1898

GLU 1413 0.09 GLN 1158 -0.09 ILE 1897

GLU 1413 0.10 GLU 1159 -0.09 ILE 1897

GLU 1413 0.08 LEU 1160 -0.09 PRO 1465

GLU 1413 0.08 LEU 1161 -0.10 PRO 1465

GLU 1413 0.08 LYS 1162 -0.10 PRO 1465

GLU 1413 0.08 PHE 1163 -0.09 PRO 1465

GLU 1413 0.07 HIS 1164 -0.11 PRO 1465

GLU 1413 0.06 SER 1165 -0.11 PRO 1465

GLU 1413 0.07 ALA 1166 -0.10 PRO 1465

GLU 1413 0.06 TYR 1167 -0.10 PRO 1465

GLU 1413 0.06 TYR 1168 -0.11 PRO 1465

GLU 1413 0.05 SER 1169 -0.12 PRO 1465

GLU 1413 0.05 SER 1170 -0.12 PRO 1465

GLU 1413 0.04 ASN 1171 -0.12 PRO 1465

GLU 1413 0.05 LEU 1172 -0.11 PRO 1465

TRP 1414 0.04 MET 1173 -0.13 PRO 1465

GLY 1755 0.04 ALA 1174 -0.14 PRO 1465

GLY 1755 0.04 VAL 1175 -0.16 PRO 1465

GLY 1755 0.05 VAL 1176 -0.19 LYS 1485

GLY 1755 0.05 VAL 1177 -0.22 LYS 1485

GLY 1755 0.06 LEU 1178 -0.27 LYS 1485

GLY 1755 0.05 GLY 1179 -0.30 LYS 1485

ALA 1845 0.06 ARG 1180 -0.36 LYS 1485

ALA 1845 0.04 GLU 1181 -0.33 LYS 1485

ALA 1845 0.04 SER 1182 -0.33 LYS 1485

ALA 1845 0.04 LEU 1183 -0.30 LYS 1485

ILE 966 0.05 ASP 1184 -0.27 LYS 1485

ILE 966 0.04 ASP 1185 -0.27 LYS 1485

ILE 966 0.03 LEU 1186 -0.25 LYS 1485

ILE 966 0.04 THR 1187 -0.23 LYS 1485

ALA 989 0.04 ASN 1188 -0.22 PRO 1465

ALA 989 0.02 LEU 1189 -0.23 PRO 1465

GLU 1413 0.03 VAL 1190 -0.21 PRO 1465

ALA 989 0.03 VAL 1191 -0.19 PRO 1465

GLU 1413 0.03 LYS 1192 -0.19 PRO 1465

GLU 1413 0.03 LEU 1193 -0.19 PRO 1465

GLU 1413 0.03 PHE 1194 -0.17 PRO 1465

GLU 1413 0.04 SER 1195 -0.17 PRO 1465

GLU 1413 0.04 GLU 1196 -0.16 PRO 1465

GLU 1413 0.04 VAL 1197 -0.15 PRO 1465

GLU 1413 0.04 GLU 1198 -0.13 PRO 1465

GLU 1413 0.04 ASN 1199 -0.12 PRO 1465

GLU 1413 0.05 LYS 1200 -0.11 PRO 1465

GLU 1413 0.05 ASN 1201 -0.11 PRO 1465

GLU 1413 0.05 VAL 1202 -0.10 PRO 1465

GLU 1413 0.05 PRO 1203 -0.09 PRO 1465

GLU 1413 0.05 LEU 1204 -0.08 PRO 1465

GLU 1413 0.05 PRO 1205 -0.07 PRO 1465

GLU 1413 0.05 GLU 1206 -0.06 PRO 1465

GLU 1413 0.04 PHE 1207 -0.05 ILE 1831

ILE 1450 0.04 PRO 1208 -0.05 ILE 1831

ILE 1450 0.05 GLU 1209 -0.06 ILE 1831

ILE 1450 0.05 HIS 1210 -0.06 ILE 1831

LEU 1532 0.05 PRO 1211 -0.07 ILE 1831

ASN 1394 0.05 PHE 1212 -0.08 ILE 1831

LYS 1563 0.04 GLN 1213 -0.07 ILE 1831

LYS 1430 0.05 GLU 1214 -0.07 ILE 1831

ASP 1426 0.05 GLU 1215 -0.08 ILE 1831

PRO 1020 0.05 HIS 1216 -0.09 ILE 1831

LYS 1563 0.05 LEU 1217 -0.08 ILE 1831

LYS 1563 0.06 LYS 1218 -0.08 ILE 1831

LYS 1563 0.05 GLN 1219 -0.09 ILE 1831

THR 1127 0.07 LEU 1220 -0.10 ILE 1831

THR 1127 0.08 TYR 1221 -0.11 ILE 1831

GLU 1152 0.07 LYS 1222 -0.12 ILE 1831

GLU 1152 0.07 ILE 1223 -0.13 ILE 1831

ARG 1148 0.08 VAL 1224 -0.14 ILE 1831

ARG 1148 0.07 PRO 1225 -0.15 ILE 1831

ARG 1148 0.07 ILE 1226 -0.16 ILE 1831

SER 1536 0.07 LYS 1227 -0.18 ILE 1831

LEU 1628 0.07 ASP 1228 -0.18 ILE 1831

LEU 1560 0.07 ILE 1229 -0.18 ILE 1831

LEU 1628 0.06 ARG 1230 -0.16 ILE 1831

LYS 1563 0.07 ASN 1231 -0.14 ILE 1831

LYS 1563 0.07 LEU 1232 -0.12 ILE 1831

GLU 1124 0.08 TYR 1233 -0.11 ILE 1831

GLU 1124 0.07 VAL 1234 -0.09 ILE 1831

GLU 1124 0.09 THR 1235 -0.08 ILE 1831

GLU 1124 0.07 PHE 1236 -0.07 ILE 1831

LYS 1125 0.06 PRO 1237 -0.06 ILE 1831

ILE 1450 0.06 ILE 1238 -0.05 ILE 1831

ILE 1450 0.06 PRO 1239 -0.04 ILE 1831

ARG 1606 0.07 ASP 1240 -0.03 PRO 1465

ARG 1606 0.08 LEU 1241 -0.03 PRO 1465

ARG 1606 0.08 GLN 1242 -0.04 PRO 1465

ARG 1606 0.08 LYS 1243 -0.04 PRO 1465

ARG 1606 0.08 TYR 1244 -0.03 PRO 1465

ARG 1606 0.09 TYR 1245 -0.05 TYR 1362

GLU 1611 0.10 LYS 1246 -0.04 TYR 1363

GLU 1611 0.09 SER 1247 -0.04 GLU 1372

ARG 1606 0.09 ASN 1248 -0.09 GLU 1372

ILE 1450 0.09 PRO 1249 -0.08 GLU 1372

ARG 1606 0.09 GLY 1250 -0.09 GLU 1372

ALA 1533 0.11 HIS 1251 -0.15 GLU 1372

GLN 1326 0.13 TYR 1252 -0.12 GLU 1372

GLN 1326 0.09 LEU 1253 -0.09 GLU 1372

GLN 1326 0.11 GLY 1254 -0.11 GLU 1372

GLN 1326 0.16 HIS 1255 -0.15 ASN 1337

GLN 1326 0.16 LEU 1256 -0.13 ASN 1337

GLN 1326 0.10 ILE 1257 -0.11 ALA 1340

GLN 1326 0.11 GLY 1258 -0.13 ALA 1340

GLN 1326 0.13 HIS 1259 -0.15 ALA 1340

GLN 1326 0.11 GLU 1260 -0.16 ASP 1345

LYS 1563 0.12 GLY 1261 -0.15 ASP 1345

LYS 1563 0.11 PRO 1262 -0.14 PHE 1343

LYS 1563 0.09 GLY 1263 -0.12 ALA 1340

LYS 1563 0.09 SER 1264 -0.13 ALA 1340

LYS 1563 0.08 LEU 1265 -0.11 ALA 1340

LYS 1563 0.09 LEU 1266 -0.12 ASP 1345

LYS 1563 0.09 SER 1267 -0.13 ASP 1345

LYS 1567 0.08 GLU 1268 -0.11 ASP 1345

LYS 1567 0.07 LEU 1269 -0.12 ILE 1830

LYS 1567 0.08 LYS 1270 -0.13 ILE 1830

LYS 1567 0.08 SER 1271 -0.13 ILE 1830

LYS 1567 0.07 LYS 1272 -0.13 ILE 1830

LYS 1567 0.07 GLY 1273 -0.14 ILE 1831

LYS 1567 0.07 TRP 1274 -0.14 ILE 1831

LYS 1567 0.07 VAL 1275 -0.14 ILE 1831

ASP 1521 0.09 ASN 1276 -0.16 ILE 1831

THR 1915 0.10 THR 1277 -0.14 TRP 1827

THR 1915 0.09 LEU 1278 -0.11 ARG 1348

THR 1915 0.10 VAL 1279 -0.12 GLY 1351

LEU 1532 0.10 GLY 1280 -0.10 TYR 1352

LEU 1532 0.11 GLY 1281 -0.09 LYS 1355

PHE 1121 0.09 GLN 1282 -0.08 LYS 1355

PHE 1121 0.11 LYS 1283 -0.09 LYS 1355

PHE 1121 0.09 GLU 1284 -0.07 GLY 1358

LYS 1125 0.08 GLY 1285 -0.07 ILE 1831

TRP 1414 0.07 ALA 1286 -0.06 ILE 1831

MET 1602 0.06 ARG 1287 -0.05 PRO 1465

MET 1602 0.06 GLY 1288 -0.05 PRO 1465

MET 1602 0.06 PHE 1289 -0.05 ILE 1831

LYS 1125 0.07 MET 1290 -0.05 ILE 1831

PHE 1121 0.08 PHE 1291 -0.06 ILE 1831

PHE 1121 0.08 PHE 1292 -0.07 LYS 1355

PHE 1121 0.10 ILE 1293 -0.08 ILE 1831

LEU 1532 0.08 ILE 1294 -0.08 ILE 1831

LEU 1120 0.09 ASN 1295 -0.11 ILE 1831

LYS 1563 0.08 VAL 1296 -0.12 ILE 1831

THR 1915 0.07 ASP 1297 -0.15 ILE 1831

LYS 1563 0.06 LEU 1298 -0.16 ILE 1831

ARG 1577 0.07 THR 1299 -0.17 ILE 1831

LEU 1628 0.07 GLU 1300 -0.18 ILE 1831

ARG 1577 0.07 GLU 1301 -0.15 ILE 1831

LYS 1567 0.06 GLY 1302 -0.15 ILE 1831

GLU 1152 0.05 LEU 1303 -0.15 ILE 1831

GLU 1152 0.05 LEU 1304 -0.14 ILE 1831

LYS 1567 0.05 HIS 1305 -0.12 ILE 1831

ILE 1424 0.05 VAL 1306 -0.12 ILE 1831

ILE 1424 0.06 GLU 1307 -0.11 ILE 1831

LYS 1563 0.05 ASP 1308 -0.10 ILE 1831

LYS 1563 0.06 ILE 1309 -0.11 ILE 1831

LYS 1563 0.06 ILE 1310 -0.10 ILE 1831

LYS 1563 0.06 LEU 1311 -0.09 ILE 1831

LYS 1563 0.06 HIS 1312 -0.09 ILE 1831

LYS 1563 0.07 MET 1313 -0.08 ILE 1831

LYS 1563 0.06 PHE 1314 -0.08 ALA 1340

LYS 1563 0.06 GLN 1315 -0.08 ALA 1340

LYS 1563 0.07 TYR 1316 -0.10 ALA 1340

LYS 1563 0.07 ILE 1317 -0.08 ALA 1340

LYS 1563 0.07 GLN 1318 -0.07 ALA 1340

LYS 1563 0.07 LYS 1319 -0.09 LEU 1333

LYS 1563 0.08 LEU 1320 -0.09 LEU 1333

LYS 1563 0.08 ARG 1321 -0.06 LEU 1333

LEU 1443 0.09 ALA 1322 -0.06 ASN 1434

LEU 1443 0.13 GLU 1323 -0.07 VAL 1329

LEU 1256 0.11 GLY 1324 -0.05 VAL 1329

LEU 1256 0.14 PRO 1325 -0.03 ASN 1434

ASN 1447 0.18 GLN 1326 -0.03 GLU 1323

ILE 1450 0.18 GLU 1327 -0.03 LYS 975

ILE 1450 0.24 TRP 1328 -0.04 LEU 1437

ILE 1450 0.24 VAL 1329 -0.11 LEU 1443

ILE 1450 0.18 PHE 1330 -0.07 LEU 1443

ILE 1450 0.19 GLN 1331 -0.07 LEU 1443

ILE 1450 0.29 GLU 1332 -0.14 LEU 1443

ILE 1450 0.19 LEU 1333 -0.16 LEU 1443

PRO 1451 0.14 LYS 1334 -0.11 LEU 1443

THR 1452 0.16 ASP 1335 -0.15 LYS 1446

PRO 1451 0.18 LEU 1336 -0.20 LYS 1446

ALA 1759 0.13 ASN 1337 -0.15 PRO 1444

ALA 1759 0.13 ALA 1338 -0.13 LYS 1446

ALA 1759 0.14 VAL 1339 -0.18 ALA 1533

LEU 1819 0.15 ALA 1340 -0.25 LEU 1532

ALA 1759 0.12 PHE 1341 -0.18 LEU 1532

ALA 1759 0.12 ARG 1342 -0.22 GLY 1534

LEU 1819 0.15 PHE 1343 -0.33 GLY 1534

ALA 1759 0.13 LYS 1344 -0.27 GLY 1534

LYS 1817 0.15 ASP 1345 -0.30 GLY 1552

LYS 1815 0.14 LYS 1346 -0.26 PHE 1486

LYS 1815 0.13 GLU 1347 -0.20 ASP 1538

LYS 1815 0.14 ARG 1348 -0.20 ASP 1538

GLY 1755 0.10 PRO 1349 -0.22 PRO 1465

GLY 1755 0.11 ARG 1350 -0.18 TYR 1466

GLY 1755 0.11 GLY 1351 -0.16 GLN 1540

GLY 1755 0.10 TYR 1352 -0.15 GLN 1540

GLY 1755 0.08 THR 1353 -0.17 PRO 1465

GLY 1755 0.08 SER 1354 -0.14 PRO 1465

GLY 1755 0.09 LYS 1355 -0.11 GLN 1540

GLY 1755 0.08 ILE 1356 -0.13 LYS 1485

GLY 1755 0.06 ALA 1357 -0.13 PRO 1465

GLY 1755 0.07 GLY 1358 -0.11 PRO 1465

MET 1602 0.07 ILE 1359 -0.10 PRO 1465

GLY 1755 0.06 LEU 1360 -0.12 LYS 1485

MET 1602 0.06 HIS 1361 -0.10 LYS 1485

MET 1602 0.07 TYR 1362 -0.09 LYS 1485

ARG 1606 0.07 TYR 1363 -0.09 LYS 1485

ARG 1606 0.06 PRO 1364 -0.11 LYS 1485

ARG 1606 0.06 LEU 1365 -0.14 LYS 1485

ARG 1757 0.07 GLU 1366 -0.13 LYS 1485

ARG 1757 0.08 GLU 1367 -0.11 LYS 1485

ARG 1757 0.08 VAL 1368 -0.13 LYS 1485

ARG 1757 0.09 LEU 1369 -0.13 PHE 1486

ARG 1757 0.09 THR 1370 -0.11 HIS 1255

ARG 1606 0.09 ALA 1371 -0.11 HIS 1255

ARG 1606 0.11 GLU 1372 -0.15 HIS 1251

ALA 1759 0.11 TYR 1373 -0.14 HIS 1255

GLU 1611 0.11 LEU 1374 -0.09 HIS 1255

GLU 1611 0.11 LEU 1375 -0.06 LEU 1443

GLU 1611 0.10 GLU 1376 -0.04 ARG 968

GLU 1611 0.10 GLU 1377 -0.03 GLY 991

ILE 1450 0.11 PHE 1378 -0.03 GLY 991

ILE 1450 0.09 ARG 1379 -0.03 GLU 1372

ILE 1450 0.10 PRO 1380 -0.03 GLU 1372

ILE 1450 0.08 ASP 1381 -0.03 GLU 1372

ILE 1450 0.08 LEU 1382 -0.04 GLU 1372

ILE 1450 0.09 ILE 1383 -0.05 GLU 1372

ILE 1450 0.08 GLU 1384 -0.04 GLU 1372

ILE 1450 0.07 MET 1385 -0.04 GLU 1372

ILE 1450 0.07 VAL 1386 -0.05 GLU 1372

ILE 1450 0.07 LEU 1387 -0.06 GLU 1372

ILE 1450 0.06 ASP 1388 -0.04 GLU 1372

ILE 1450 0.06 LYS 1389 -0.04 ILE 1831

LYS 1563 0.06 LEU 1390 -0.05 ILE 1831

LYS 1563 0.06 ARG 1391 -0.06 ILE 1831

LYS 1563 0.06 PRO 1392 -0.07 ILE 1831

LYS 1563 0.06 GLU 1393 -0.06 ILE 1831

LYS 1563 0.06 ASN 1394 -0.06 ILE 1831

LYS 1563 0.06 VAL 1395 -0.08 ILE 1831

THR 1127 0.07 ARG 1396 -0.09 ILE 1831

THR 1127 0.07 VAL 1397 -0.10 ILE 1831

THR 1127 0.07 ALA 1398 -0.11 ILE 1831

LYS 1563 0.06 ILE 1399 -0.13 ILE 1831

LYS 1563 0.06 VAL 1400 -0.14 ILE 1831

GLU 1152 0.06 SER 1401 -0.15 ILE 1831

GLU 1152 0.07 LYS 1402 -0.16 ILE 1831

GLU 1152 0.08 SER 1403 -0.15 ILE 1831

GLU 1152 0.08 PHE 1404 -0.14 ILE 1831

GLU 1152 0.10 GLU 1405 -0.14 ILE 1831

GLU 1152 0.11 GLY 1406 -0.13 ILE 1831

GLU 1152 0.10 LYS 1407 -0.12 ILE 1831

GLU 1152 0.11 THR 1408 -0.12 ILE 1831

GLU 1152 0.12 ASP 1409 -0.11 ILE 1831

GLU 1152 0.12 ARG 1410 -0.11 ILE 1831

ARG 1148 0.13 THR 1411 -0.11 ILE 1831

ASN 1021 0.12 GLU 1412 -0.11 ILE 1831

THR 1144 0.18 GLU 1413 -0.10 ILE 1831

PHE 1137 0.16 TRP 1414 -0.10 ILE 1831

THR 1144 0.11 TYR 1415 -0.11 ILE 1831

THR 1144 0.13 GLY 1416 -0.12 ILE 1831

ARG 1148 0.10 THR 1417 -0.12 ILE 1831

ARG 1148 0.10 GLN 1418 -0.12 ILE 1831

GLU 1152 0.09 TYR 1419 -0.12 ILE 1831

GLU 1152 0.09 LYS 1420 -0.11 ILE 1831

GLU 1152 0.08 GLN 1421 -0.10 ILE 1831

GLU 1152 0.07 GLU 1422 -0.10 ILE 1831

GLU 1152 0.06 ALA 1423 -0.09 ILE 1831

GLU 1307 0.06 ILE 1424 -0.09 ILE 1831

GLU 1152 0.05 PRO 1425 -0.08 ILE 1831

GLU 1152 0.05 ASP 1426 -0.08 ILE 1831

LYS 1563 0.05 GLU 1427 -0.08 ILE 1831

LYS 1563 0.05 VAL 1428 -0.09 ILE 1831

LYS 1563 0.05 ILE 1429 -0.08 ILE 1831

GLU 1214 0.05 LYS 1430 -0.07 ILE 1831

LYS 1563 0.05 LYS 1431 -0.08 ILE 1831

LYS 1563 0.05 TRP 1432 -0.08 ILE 1831

LYS 1563 0.05 GLN 1433 -0.07 ILE 1831

ALA 1656 0.05 ASN 1434 -0.07 ILE 1831

ALA 1656 0.05 ALA 1435 -0.06 ILE 1831

ALA 1656 0.05 ASP 1436 -0.07 ALA 1340

ALA 1656 0.06 LEU 1437 -0.07 ALA 1340

GLU 1566 0.06 ASN 1438 -0.09 ALA 1340

THR 1570 0.06 GLY 1439 -0.09 ALA 1340

THR 1570 0.07 LYS 1440 -0.10 ALA 1340

LYS 1563 0.07 PHE 1441 -0.11 ALA 1340

LYS 1563 0.08 LYS 1442 -0.13 LEU 1336

GLU 1323 0.13 LEU 1443 -0.16 LEU 1336

GLN 1326 0.16 PRO 1444 -0.18 LEU 1336

GLN 1326 0.15 THR 1445 -0.18 LEU 1336

GLN 1326 0.15 LYS 1446 -0.20 LEU 1336

TRP 1328 0.21 ASN 1447 -0.19 PHE 1343

TRP 1328 0.17 GLU 1448 -0.16 PHE 1343

VAL 1329 0.19 PHE 1449 -0.19 PHE 1343

GLU 1332 0.29 ILE 1450 -0.23 PHE 1343

GLU 1332 0.25 PRO 1451 -0.22 PHE 1343

GLU 1332 0.22 THR 1452 -0.20 GLU 978

GLU 1332 0.17 ASN 1453 -0.22 GLU 978

LEU 1336 0.17 PHE 1454 -0.28 GLU 978

TRP 1827 0.19 GLU 1455 -0.24 GLU 978

TRP 1827 0.23 ILE 1456 -0.27 LYS 980

ILE 1831 0.24 LEU 1457 -0.25 LYS 980

ILE 1831 0.25 PRO 1458 -0.29 PRO 1000

ILE 1830 0.28 LEU 1459 -0.34 THR 1001

ILE 1831 0.28 GLU 1460 -0.31 THR 1001

ILE 1831 0.28 LYS 1461 -0.32 THR 1001

ILE 1830 0.32 GLU 1462 -0.33 THR 1001

ILE 1830 0.36 ALA 1463 -0.39 THR 1001

ILE 1830 0.44 THR 1464 -0.40 THR 1001

TYR 1835 0.51 PRO 1465 -0.46 LYS 1815

ILE 1830 0.64 TYR 1466 -0.51 LYS 1815

ILE 1830 0.65 PRO 1467 -0.42 LYS 1815

ILE 1831 0.49 ALA 1468 -0.41 ASP 1838

ILE 1831 0.46 LEU 1469 -0.45 ASP 1838

ILE 1831 0.36 ILE 1470 -0.34 ASP 1838

ILE 1831 0.28 LYS 1471 -0.34 PHE 1837

ILE 1831 0.23 ASP 1472 -0.48 HIS 1930

ARG 1684 0.16 THR 1473 -0.49 HIS 1930

ARG 1919 0.15 ALA 1474 -0.55 HIS 1930

VAL 1612 0.15 MET 1475 -0.48 HIS 1930

ARG 1684 0.22 SER 1476 -0.46 HIS 1930

ARG 1684 0.27 LYS 1477 -0.45 HIS 1930

ILE 1831 0.40 LEU 1478 -0.40 PHE 1837

ILE 1831 0.56 TRP 1479 -0.40 PHE 1837

ILE 1831 0.47 PHE 1480 -0.31 LYS 1815

TRP 1827 0.46 LYS 1481 -0.35 THR 1001

TRP 1827 0.38 GLN 1482 -0.35 THR 1001

TRP 1827 0.40 ASP 1483 -0.40 THR 1001

TRP 1827 0.36 ASP 1484 -0.48 THR 1001

SER 1823 0.39 LYS 1485 -0.58 THR 1001

LEU 1819 0.38 PHE 1486 -0.44 LYS 980

SER 1823 0.29 PHE 1487 -0.41 LYS 980

SER 1823 0.27 LEU 1488 -0.40 GLU 978

TRP 1827 0.21 PRO 1489 -0.32 GLU 978

TRP 1827 0.22 LYS 1490 -0.26 GLU 978

TRP 1827 0.29 ALA 1491 -0.24 THR 1001

ILE 1831 0.26 ASN 1492 -0.36 LEU 1819

ILE 1831 0.26 LEU 1493 -0.30 LEU 1819

TYR 1685 0.28 ASN 1494 -0.43 SER 1823

ARG 1684 0.27 PHE 1495 -0.38 SER 1823

VAL 1612 0.27 GLU 1496 -0.59 ILE 1830

VAL 1612 0.24 PHE 1497 -0.50 ILE 1830

VAL 1612 0.25 PHE 1498 -0.55 ILE 1830

THR 1915 0.21 SER 1499 -0.48 GLN 1833

THR 1915 0.21 PRO 1500 -0.50 GLN 1833

THR 1915 0.20 PHE 1501 -0.43 GLN 1833

THR 1915 0.24 ALA 1502 -0.44 GLN 1833

THR 1915 0.29 TYR 1503 -0.45 GLN 1833

THR 1915 0.24 VAL 1504 -0.41 GLN 1833

GLU 1916 0.23 ASP 1505 -0.35 GLN 1833

THR 1915 0.24 PRO 1506 -0.32 ILE 1831

GLU 1916 0.18 LEU 1507 -0.30 GLN 1833

THR 1915 0.19 HIS 1508 -0.34 GLN 1833

THR 1915 0.24 SER 1509 -0.38 ILE 1831

THR 1915 0.20 ASN 1510 -0.33 ILE 1831

THR 1915 0.17 MET 1511 -0.31 ILE 1831

THR 1915 0.20 ALA 1512 -0.36 ILE 1831

THR 1915 0.20 TYR 1513 -0.35 ILE 1831

THR 1915 0.16 LEU 1514 -0.29 ILE 1831

THR 1915 0.16 TYR 1515 -0.28 ILE 1830

THR 1915 0.18 LEU 1516 -0.30 ILE 1830

THR 1915 0.16 GLU 1517 -0.27 TRP 1827

THR 1915 0.14 LEU 1518 -0.23 ILE 1830

THR 1915 0.15 LEU 1519 -0.23 ILE 1830

THR 1915 0.15 LYS 1520 -0.23 TRP 1827

THR 1915 0.12 ASP 1521 -0.20 TRP 1827

LYS 1567 0.13 SER 1522 -0.16 ILE 1830

ILE 1564 0.15 LEU 1523 -0.16 ASP 1345

THR 1915 0.14 ASN 1524 -0.17 ASP 1345

LYS 1563 0.14 GLU 1525 -0.15 ASP 1345

LYS 1563 0.20 TYR 1526 -0.15 ASP 1345

LEU 1560 0.16 ALA 1527 -0.17 ASP 1345

THR 1915 0.14 TYR 1528 -0.19 ASP 1345

VAL 1329 0.16 ALA 1529 -0.19 PHE 1343

GLU 1611 0.16 ALA 1530 -0.21 PHE 1343

LEU 1607 0.16 GLU 1531 -0.23 ASP 1345

VAL 1329 0.18 LEU 1532 -0.25 ALA 1340

VAL 1329 0.20 ALA 1533 -0.27 PHE 1343

ARG 1606 0.17 GLY 1534 -0.33 PHE 1343

GLU 1611 0.18 LEU 1535 -0.25 ASP 1345

ARG 1606 0.19 SER 1536 -0.26 ASP 1345

GLU 1611 0.20 TYR 1537 -0.24 LEU 1819

ALA 1613 0.22 ASP 1538 -0.31 SER 1823

ALA 1613 0.22 LEU 1539 -0.33 TRP 1827

ALA 1613 0.25 GLN 1540 -0.41 TRP 1827

ALA 1613 0.29 ASN 1541 -0.48 ILE 1831

ALA 1613 0.40 THR 1542 -0.67 ILE 1831

ALA 1613 0.50 ILE 1543 -0.68 ILE 1831

VAL 1612 0.41 TYR 1544 -0.70 ILE 1831

VAL 1612 0.29 GLY 1545 -0.56 ILE 1831

VAL 1612 0.26 MET 1546 -0.49 ILE 1830

VAL 1612 0.28 TYR 1547 -0.51 TRP 1827

VAL 1612 0.24 LEU 1548 -0.38 SER 1823

GLU 1611 0.25 SER 1549 -0.40 SER 1823

GLU 1611 0.22 VAL 1550 -0.27 LEU 1819

GLU 1611 0.22 LYS 1551 -0.27 LEU 1819

GLU 1611 0.20 GLY 1552 -0.30 ASP 1345

GLU 1611 0.19 TYR 1553 -0.29 PHE 1343

ILE 1831 0.19 ASN 1554 -0.23 GLU 978

GLU 1611 0.18 ASP 1555 -0.20 GLU 978

GLU 1611 0.18 LYS 1556 -0.17 GLU 978

GLU 1611 0.20 GLN 1557 -0.19 ASP 1345

GLU 1611 0.19 PRO 1558 -0.17 THR 1001

GLU 1611 0.16 ILE 1559 -0.15 THR 1001

GLU 1611 0.17 LEU 1560 -0.18 ASP 1345

VAL 1612 0.19 LEU 1561 -0.20 LEU 1819

VAL 1612 0.16 LYS 1562 -0.17 THR 1001

TYR 1526 0.20 LYS 1563 -0.16 HIS 1930

THR 1915 0.17 ILE 1564 -0.20 SER 1823

THR 1915 0.16 ILE 1565 -0.22 HIS 1930

THR 1915 0.13 GLU 1566 -0.21 HIS 1930

THR 1915 0.13 LYS 1567 -0.21 HIS 1930

THR 1915 0.15 MET 1568 -0.24 HIS 1930

THR 1915 0.13 ALA 1569 -0.26 HIS 1930

THR 1915 0.11 THR 1570 -0.24 HIS 1930

THR 1915 0.11 PHE 1571 -0.23 HIS 1930

GLU 1916 0.10 GLU 1572 -0.21 HIS 1930

GLU 1916 0.09 ILE 1573 -0.21 ILE 1830

GLU 1916 0.08 ASP 1574 -0.20 ILE 1830

GLU 1916 0.07 GLU 1575 -0.20 ILE 1830

GLU 1916 0.07 LYS 1576 -0.19 ILE 1830

GLU 1916 0.08 ARG 1577 -0.20 ILE 1830

LYS 1632 0.09 PHE 1578 -0.22 ILE 1830

LEU 1628 0.12 GLU 1579 -0.21 ILE 1831

LEU 1628 0.08 ILE 1580 -0.21 ILE 1831

THR 1915 0.09 ILE 1581 -0.24 ILE 1831

LEU 1628 0.13 LYS 1582 -0.24 ILE 1831

LEU 1628 0.11 GLU 1583 -0.22 ILE 1831

ASN 1913 0.09 ALA 1584 -0.23 ILE 1831

GLU 1517 0.11 TYR 1585 -0.26 ILE 1831

ASN 1913 0.10 MET 1586 -0.23 ILE 1831

ASN 1913 0.09 ARG 1587 -0.22 ILE 1831

GLU 1517 0.12 SER 1588 -0.24 ILE 1831

GLN 1540 0.12 LEU 1589 -0.24 ILE 1831

ASN 1913 0.10 ASN 1590 -0.20 ILE 1831

ASP 1538 0.11 ASN 1591 -0.20 ILE 1831

ASP 1538 0.13 PHE 1592 -0.21 ILE 1831

ASP 1538 0.11 ARG 1593 -0.18 ILE 1831

SER 1536 0.11 ALA 1594 -0.17 ILE 1831

SER 1536 0.13 GLU 1595 -0.18 ILE 1831

SER 1536 0.12 GLN 1596 -0.17 ILE 1831

LYS 1551 0.13 PRO 1597 -0.15 ILE 1831

LYS 1551 0.14 HIS 1598 -0.16 ILE 1831

LYS 1551 0.16 GLN 1599 -0.19 ILE 1831

LYS 1551 0.16 HIS 1600 -0.16 ILE 1831

LYS 1551 0.16 ALA 1601 -0.14 ILE 1831

LYS 1551 0.18 MET 1602 -0.17 ILE 1831

LYS 1551 0.20 TYR 1603 -0.17 ILE 1831

SER 1549 0.19 TYR 1604 -0.12 ILE 1831

ASN 1492 0.19 LEU 1605 -0.10 ILE 1831

ASN 1494 0.22 ARG 1606 -0.15 ASP 1505

THR 1542 0.27 LEU 1607 -0.11 GLN 1833

THR 1542 0.22 LEU 1608 -0.07 GLN 1833

ASN 1494 0.22 MET 1609 -0.10 ASP 1505

ASN 1494 0.25 THR 1610 -0.16 ASP 1505

ILE 1543 0.34 GLU 1611 -0.15 ASP 1505

ILE 1543 0.49 VAL 1612 -0.18 ASP 1505

ILE 1543 0.50 ALA 1613 -0.21 ASP 1505

ILE 1543 0.40 TRP 1614 -0.16 GLN 1833

ILE 1543 0.24 THR 1615 -0.17 ILE 1831

ASN 1541 0.19 LYS 1616 -0.20 ILE 1831

ASN 1913 0.23 ASP 1617 -0.17 ILE 1831

ASN 1913 0.25 GLU 1618 -0.19 ILE 1831

ASN 1913 0.19 LEU 1619 -0.25 ILE 1831

ASN 1913 0.18 LYS 1620 -0.23 ILE 1831

ASN 1913 0.19 GLU 1621 -0.21 ILE 1831

ASN 1913 0.18 ALA 1622 -0.23 ILE 1831

ASN 1913 0.16 LEU 1623 -0.24 ILE 1831

ASN 1913 0.14 ASP 1624 -0.22 ILE 1831

ASN 1913 0.14 ASP 1625 -0.23 GLN 1833

ASN 1913 0.14 VAL 1626 -0.24 ILE 1831

ASN 1913 0.12 THR 1627 -0.22 GLN 1833

LYS 1582 0.13 LEU 1628 -0.22 ILE 1830

GLU 1916 0.11 PRO 1629 -0.22 HIS 1930

GLU 1916 0.12 ARG 1630 -0.24 GLN 1833

GLU 1916 0.13 LEU 1631 -0.26 ILE 1830

GLU 1916 0.12 LYS 1632 -0.25 HIS 1930

GLU 1916 0.12 ALA 1633 -0.27 HIS 1930

GLU 1916 0.14 PHE 1634 -0.29 GLN 1833

THR 1915 0.14 ILE 1635 -0.30 ILE 1830

GLU 1916 0.12 PRO 1636 -0.31 HIS 1930

GLU 1916 0.14 GLN 1637 -0.33 HIS 1930

THR 1915 0.16 LEU 1638 -0.35 HIS 1930

THR 1915 0.15 LEU 1639 -0.35 HIS 1930

GLU 1916 0.13 SER 1640 -0.36 HIS 1930

THR 1915 0.14 ARG 1641 -0.41 HIS 1930

THR 1915 0.17 LEU 1642 -0.45 HIS 1930

VAL 1612 0.19 HIS 1643 -0.50 HIS 1930

VAL 1612 0.22 ILE 1644 -0.48 TYR 1835

ARG 1684 0.32 GLU 1645 -0.56 TYR 1835

ILE 1831 0.34 ALA 1646 -0.41 TYR 1826

ILE 1831 0.52 LEU 1647 -0.35 GLU 1822

ILE 1831 0.40 LEU 1648 -0.30 LEU 1819

TRP 1827 0.46 HIS 1649 -0.34 LEU 1819

TRP 1827 0.40 GLY 1650 -0.31 THR 1001

TRP 1827 0.31 ASN 1651 -0.29 THR 1001

ILE 1831 0.28 ILE 1652 -0.26 THR 1001

ILE 1831 0.29 THR 1653 -0.26 THR 1001

ILE 1831 0.31 LYS 1654 -0.26 THR 1001

ILE 1831 0.25 GLN 1655 -0.22 THR 1001

ILE 1831 0.24 ALA 1656 -0.22 THR 1001

ILE 1831 0.29 ALA 1657 -0.25 THR 1001

ILE 1831 0.24 LEU 1658 -0.23 THR 1001

ILE 1831 0.18 GLY 1659 -0.21 THR 1001

GLU 1611 0.19 ILE 1660 -0.22 THR 1001

ARG 1684 0.20 MET 1661 -0.26 PHE 1837

GLU 1611 0.16 GLN 1662 -0.24 HIS 1930

VAL 1612 0.15 MET 1663 -0.22 HIS 1930

VAL 1612 0.17 VAL 1664 -0.26 HIS 1930

THR 1915 0.15 GLU 1665 -0.32 HIS 1930

THR 1915 0.13 ASP 1666 -0.28 HIS 1930

THR 1915 0.13 THR 1667 -0.27 HIS 1930

THR 1915 0.14 LEU 1668 -0.31 HIS 1930

THR 1915 0.12 ILE 1669 -0.31 HIS 1930

THR 1915 0.11 GLU 1670 -0.27 HIS 1930

THR 1915 0.11 HIS 1671 -0.27 HIS 1930

THR 1915 0.12 ALA 1672 -0.31 HIS 1930

GLU 1916 0.11 HIS 1673 -0.32 HIS 1930

THR 1915 0.13 THR 1674 -0.36 HIS 1930

GLU 1916 0.13 LYS 1675 -0.40 HIS 1930

THR 1915 0.14 PRO 1676 -0.47 HIS 1930

THR 1915 0.16 LEU 1677 -0.50 HIS 1930

ARG 1919 0.17 LEU 1678 -0.53 PRO 1929

ARG 1919 0.17 PRO 1679 -0.67 PRO 1929

ARG 1919 0.20 SER 1680 -0.62 PRO 1929

ARG 1919 0.22 GLN 1681 -0.55 PRO 1929

LYS 1477 0.18 LEU 1682 -0.68 PRO 1929

GLU 1645 0.25 VAL 1683 -0.53 PRO 1929

ALA 1646 0.32 ARG 1684 -0.33 PRO 1929

LEU 1647 0.30 TYR 1685 -0.37 VAL 1504

LEU 1647 0.27 ARG 1686 -0.22 VAL 1504

LEU 1647 0.22 GLU 1687 -0.16 ASP 1505

ASN 1494 0.20 VAL 1688 -0.08 ASP 1505

TYR 1466 0.18 GLN 1689 -0.06 MET 1718

ASN 1492 0.15 LEU 1690 -0.05 GLY 1920

TYR 1466 0.14 PRO 1691 -0.07 GLY 1920

TYR 1466 0.13 ASP 1692 -0.05 GLY 1920

ASN 1492 0.12 ARG 1693 -0.04 GLY 1920

ASN 1492 0.13 GLY 1694 -0.04 PHE 1917

ASN 1492 0.13 TRP 1695 -0.03 ILE 1831

ASN 1492 0.14 PHE 1696 -0.03 ILE 1831

ASN 1492 0.14 VAL 1697 -0.06 ILE 1831

ASP 1617 0.15 TYR 1698 -0.07 ILE 1831

ASP 1617 0.16 GLN 1699 -0.08 ILE 1831

ASP 1617 0.19 GLN 1700 -0.10 ILE 1831

ASP 1617 0.14 ARG 1701 -0.11 ILE 1831

SER 1536 0.11 ASN 1702 -0.13 ILE 1831

SER 1536 0.10 GLU 1703 -0.14 ILE 1831

SER 1536 0.09 VAL 1704 -0.14 ILE 1831

SER 1536 0.10 HIS 1705 -0.14 ILE 1831

SER 1536 0.09 ASN 1706 -0.12 ILE 1831

LYS 1551 0.09 ASN 1707 -0.12 ILE 1831

LYS 1551 0.10 SER 1708 -0.11 ILE 1831

LYS 1551 0.12 GLY 1709 -0.12 ILE 1831

LYS 1551 0.13 ILE 1710 -0.10 ILE 1831

LYS 1551 0.14 GLU 1711 -0.10 ILE 1831

ASN 1492 0.13 ILE 1712 -0.08 ILE 1831

ASN 1492 0.14 TYR 1713 -0.08 ILE 1831

ASN 1492 0.13 TYR 1714 -0.07 VAL 1504

ASN 1492 0.15 GLN 1715 -0.10 VAL 1504

LYS 1485 0.14 THR 1716 -0.11 VAL 1504

LYS 1485 0.17 ASP 1717 -0.14 VAL 1504

TYR 1466 0.21 MET 1718 -0.20 LEU 1682

LYS 1485 0.22 GLN 1719 -0.27 LEU 1682

LYS 1485 0.20 SER 1720 -0.28 SER 1680

LYS 1485 0.17 THR 1721 -0.30 PRO 1679

HIS 1930 0.14 SER 1722 -0.25 PRO 1679

LYS 1485 0.14 GLU 1723 -0.21 PRO 1679

LYS 1485 0.16 ASN 1724 -0.22 LEU 1682

ARG 1812 0.13 MET 1725 -0.22 PRO 1679

ARG 1812 0.12 PHE 1726 -0.18 PRO 1679

ARG 1812 0.14 LEU 1727 -0.16 LEU 1682

ARG 1812 0.19 GLU 1728 -0.18 LEU 1682

ARG 1812 0.16 LEU 1729 -0.17 PRO 1679

ARG 1812 0.13 PHE 1730 -0.14 PRO 1679

ARG 1812 0.14 ALA 1731 -0.14 LEU 1682

ARG 1812 0.14 GLN 1732 -0.15 TYR 1544

ARG 1812 0.11 ILE 1733 -0.13 PRO 1679

VAL 1782 0.10 ILE 1734 -0.13 MET 1796

ARG 1811 0.10 SER 1735 -0.12 ILE 1831

SER 1056 0.12 GLU 1736 -0.12 ASN 1044

SER 1051 0.10 PRO 1737 -0.12 SER 1792

SER 1056 0.08 ALA 1738 -0.11 ILE 1831

SER 1056 0.11 PHE 1739 -0.12 ILE 1831

SER 1056 0.11 ASN 1740 -0.11 ILE 1831

SER 1056 0.09 THR 1741 -0.12 THR 1788

SER 1056 0.07 LEU 1742 -0.11 PHE 1785

ASN 1058 0.08 ARG 1743 -0.11 ILE 1831

SER 1057 0.09 THR 1744 -0.10 ILE 1831

SER 1047 0.08 LYS 1745 -0.15 LEU 1899

SER 1056 0.07 GLU 1746 -0.15 LEU 1899

ASN 1058 0.06 GLN 1747 -0.11 LEU 1899

LYS 1551 0.07 LEU 1748 -0.10 ILE 1831

GLY 1534 0.08 GLY 1749 -0.11 ILE 1831

GLY 1534 0.08 TYR 1750 -0.13 ILE 1831

GLY 1552 0.09 ILE 1751 -0.14 ILE 1831

GLY 1552 0.09 VAL 1752 -0.13 ILE 1831

GLY 1351 0.11 PHE 1753 -0.14 ILE 1831

LYS 1817 0.11 SER 1754 -0.12 ILE 1831

LYS 1817 0.14 GLY 1755 -0.14 SER 1832

PRO 1816 0.16 PRO 1756 -0.15 VAL 1504

ASN 1492 0.18 ARG 1757 -0.16 VAL 1504

LYS 1485 0.20 ARG 1758 -0.21 VAL 1504

ASN 1492 0.24 ALA 1759 -0.24 VAL 1504

TYR 1466 0.28 ASN 1760 -0.30 VAL 1504

TYR 1466 0.27 GLY 1761 -0.26 VAL 1504

TYR 1466 0.21 ILE 1762 -0.20 VAL 1504

LYS 1485 0.18 GLN 1763 -0.17 VAL 1504

LYS 1485 0.15 GLY 1764 -0.12 VAL 1504

ALA 1491 0.14 LEU 1765 -0.10 VAL 1504

ASN 1492 0.14 ARG 1766 -0.10 MET 1789

LYS 1551 0.13 PHE 1767 -0.10 ILE 1831

LYS 1551 0.13 ILE 1768 -0.13 ILE 1831

LYS 1551 0.11 ILE 1769 -0.12 ILE 1831

LYS 1551 0.11 GLN 1770 -0.12 ILE 1831

LYS 1551 0.09 SER 1771 -0.11 ILE 1831

LYS 1551 0.08 GLU 1772 -0.10 ILE 1831

LYS 1551 0.09 LYS 1773 -0.09 ILE 1831

LYS 1551 0.10 PRO 1774 -0.08 ILE 1831

LYS 1551 0.11 PRO 1775 -0.08 ILE 1831

LYS 1551 0.11 HIS 1776 -0.06 ILE 1831

LYS 1551 0.09 TYR 1777 -0.07 ILE 1831

LYS 1551 0.09 LEU 1778 -0.08 ILE 1831

LYS 1551 0.10 GLU 1779 -0.07 ILE 1831

LYS 1551 0.09 SER 1780 -0.06 ILE 1831

ALA 1491 0.07 ARG 1781 -0.09 GLU 1746

ILE 1734 0.10 VAL 1782 -0.08 PHE 1767

ARG 1812 0.09 GLU 1783 -0.07 GLU 1746

ARG 1812 0.08 ALA 1784 -0.10 GLU 1746

ARG 1812 0.09 PHE 1785 -0.11 LEU 1742

ARG 1812 0.10 LEU 1786 -0.10 ARG 1766

ARG 1812 0.08 ILE 1787 -0.08 GLU 1746

ARG 1812 0.07 THR 1788 -0.12 THR 1741

ARG 1812 0.08 MET 1789 -0.11 ALA 1738

ARG 1812 0.08 GLU 1790 -0.10 LEU 1682

ARG 1812 0.06 LYS 1791 -0.09 PRO 1679

ASN 1898 0.06 SER 1792 -0.12 PRO 1737

PHE 1801 0.08 ILE 1793 -0.13 PRO 1679

ARG 1812 0.05 GLU 1794 -0.12 PRO 1679

ASN 1898 0.05 ASP 1795 -0.12 PRO 1679

ASN 1898 0.06 MET 1796 -0.14 PRO 1679

ASN 1898 0.05 THR 1797 -0.15 PRO 1679

ASP 1003 0.04 GLU 1798 -0.17 PRO 1679

ASP 1003 0.04 GLU 1799 -0.18 TYR 1466

ILE 1793 0.05 ALA 1800 -0.17 TYR 1466

ILE 1793 0.08 PHE 1801 -0.17 PRO 1679

ASP 1003 0.06 GLN 1802 -0.20 TYR 1466

MET 1789 0.06 LYS 1803 -0.21 TYR 1466

MET 1789 0.08 HIS 1804 -0.19 TYR 1466

GLU 1790 0.07 ILE 1805 -0.21 TYR 1466

ASP 1003 0.09 GLN 1806 -0.26 TYR 1466

ASP 1003 0.07 ALA 1807 -0.24 TYR 1466

LEU 1729 0.10 LEU 1808 -0.23 TYR 1466

ASP 1003 0.09 ALA 1809 -0.29 TYR 1466

ASP 1003 0.11 ILE 1810 -0.33 TYR 1466

GLN 1732 0.13 ARG 1811 -0.28 TYR 1466

GLU 1728 0.19 ARG 1812 -0.30 TYR 1466

GLU 1728 0.12 LEU 1813 -0.41 TYR 1466

PRO 1756 0.13 ASP 1814 -0.42 TYR 1466

PRO 1756 0.14 LYS 1815 -0.51 TYR 1466

ARG 1758 0.18 PRO 1816 -0.29 TYR 1466

ARG 1758 0.16 LYS 1817 -0.27 TYR 1466

ALA 1759 0.15 LYS 1818 -0.24 HIS 1649

PHE 1486 0.38 LEU 1819 -0.36 ASN 1492

PHE 1486 0.26 SER 1820 -0.33 SER 1549

ALA 1759 0.18 ALA 1821 -0.23 TYR 1547

LYS 1485 0.32 GLU 1822 -0.35 LEU 1647

LYS 1485 0.39 SER 1823 -0.43 ASN 1494

GLY 1650 0.26 ALA 1824 -0.32 TYR 1547

LYS 1485 0.26 LYS 1825 -0.32 GLU 1496

TYR 1466 0.39 TYR 1826 -0.50 GLU 1496

PRO 1467 0.48 TRP 1827 -0.54 GLU 1496

TYR 1466 0.31 GLY 1828 -0.40 THR 1542

TYR 1466 0.40 GLU 1829 -0.42 TYR 1544

PRO 1467 0.65 ILE 1830 -0.59 TYR 1544

TRP 1479 0.56 ILE 1831 -0.70 TYR 1544

PRO 1467 0.41 SER 1832 -0.52 TYR 1544

TYR 1466 0.50 GLN 1833 -0.64 TYR 1544

TYR 1466 0.43 GLN 1834 -0.48 LEU 1682

TYR 1466 0.62 TYR 1835 -0.56 GLU 1645

PRO 1465 0.34 ASN 1836 -0.46 GLU 1645

PRO 1465 0.33 PHE 1837 -0.48 GLU 1645

LYS 1485 0.26 ASP 1838 -0.45 LEU 1469

LYS 1485 0.20 ARG 1839 -0.34 GLU 1645

LYS 1485 0.16 ASP 1840 -0.32 LEU 1469

LYS 1485 0.15 ASN 1841 -0.37 LEU 1469

LYS 1485 0.15 THR 1842 -0.33 LEU 1469

LYS 1485 0.13 GLU 1843 -0.30 PRO 1679

GLU 978 0.10 VAL 1844 -0.26 LEU 1469

GLU 978 0.11 ALA 1845 -0.28 LEU 1469

GLU 978 0.09 TYR 1846 -0.27 PRO 1679

GLU 978 0.09 LEU 1847 -0.24 PRO 1679

ASP 1003 0.09 LYS 1848 -0.23 PRO 1679

GLU 978 0.08 THR 1849 -0.23 PRO 1679

GLU 978 0.07 LEU 1850 -0.21 PRO 1679

GLU 978 0.06 THR 1851 -0.18 PRO 1679

ARG 1812 0.06 LYS 1852 -0.16 PRO 1679

HIS 1930 0.08 GLU 1853 -0.14 PRO 1679

HIS 1930 0.09 ASP 1854 -0.16 PRO 1679

ARG 1812 0.10 ILE 1855 -0.15 PRO 1679

ARG 1812 0.09 ILE 1856 -0.12 PRO 1679

HIS 1930 0.10 LYS 1857 -0.12 PRO 1679

HIS 1930 0.11 PHE 1858 -0.13 PRO 1679

ARG 1812 0.10 TYR 1859 -0.10 LEU 1682

HIS 1930 0.10 LYS 1860 -0.08 LEU 1682

HIS 1930 0.12 GLU 1861 -0.07 LEU 1682

LYS 1485 0.11 MET 1862 -0.08 LEU 1682

ARG 1812 0.10 LEU 1863 -0.08 LEU 1682

ARG 1812 0.09 ALA 1864 -0.06 LEU 1682

ALA 1491 0.09 VAL 1865 -0.04 GLU 1746

ALA 1491 0.09 ASP 1866 -0.04 GLU 1095

HIS 1930 0.10 ALA 1867 -0.05 LEU 1682

HIS 1930 0.11 PRO 1868 -0.04 LYS 1042

LYS 1485 0.12 ARG 1869 -0.05 LEU 1682

ALA 1491 0.12 ARG 1870 -0.04 LEU 1682

ASN 1492 0.13 HIS 1871 -0.05 ASP 1505

ASN 1492 0.13 LYS 1872 -0.04 ILE 1793

ASN 1492 0.14 VAL 1873 -0.05 ILE 1831

ASN 1492 0.14 SER 1874 -0.07 ILE 1831

LYS 1551 0.15 VAL 1875 -0.08 ILE 1831

LYS 1551 0.13 HIS 1876 -0.09 ILE 1831

LYS 1551 0.13 VAL 1877 -0.11 ILE 1831

ASP 1617 0.11 LEU 1878 -0.10 ILE 1831

LYS 1551 0.10 ALA 1879 -0.11 ILE 1831

GLU 1621 0.09 ARG 1880 -0.11 ILE 1831

GLU 1621 0.10 GLU 1881 -0.10 ILE 1831

GLU 1621 0.10 MET 1882 -0.09 ILE 1831

GLU 1621 0.13 ASP 1883 -0.08 ILE 1831

ASP 1617 0.13 SER 1884 -0.07 ILE 1831

ASP 1617 0.11 CYS 1885 -0.07 ILE 1831

ASP 1617 0.12 PRO 1886 -0.05 ILE 1831

LYS 1551 0.12 VAL 1887 -0.05 ILE 1831

LYS 1551 0.10 VAL 1888 -0.05 ILE 1831

LYS 1551 0.09 GLY 1889 -0.05 ILE 1831

LYS 1551 0.08 GLU 1890 -0.05 ASN 1150

ASP 1617 0.07 PHE 1891 -0.07 ASN 1150

ASP 1617 0.06 PRO 1892 -0.08 ASN 1150

ASP 1617 0.05 CYS 1893 -0.09 ASN 1150

ARG 1812 0.06 GLN 1894 -0.10 GLU 1746

ARG 1812 0.06 ASN 1895 -0.09 GLU 1746

ARG 1812 0.06 ASP 1896 -0.11 GLU 1095

ARG 1812 0.05 ILE 1897 -0.13 GLU 1095

SER 1792 0.06 ASN 1898 -0.14 SER 1096

ARG 1812 0.06 LEU 1899 -0.15 GLU 1746

ARG 1812 0.06 SER 1900 -0.15 GLU 1746

ARG 1812 0.06 GLN 1901 -0.10 GLU 1746

ALA 1491 0.07 ALA 1902 -0.08 GLU 1746

ALA 1491 0.07 PRO 1903 -0.07 GLU 1746

ALA 1491 0.08 ALA 1904 -0.05 GLU 1746

ASN 1492 0.09 LEU 1905 -0.05 GLU 1746

ASN 1492 0.10 PRO 1906 -0.04 GLU 1746

ASN 1492 0.11 GLN 1907 -0.03 GLY 1153

ASN 1492 0.12 PRO 1908 -0.03 ILE 1831

ASN 1492 0.13 GLU 1909 -0.03 ILE 1831

ASP 1617 0.14 VAL 1910 -0.03 ILE 1831

ILE 1543 0.17 ILE 1911 -0.04 GLN 1833

GLU 1618 0.21 GLN 1912 -0.04 GLN 1833

GLU 1618 0.25 ASN 1913 -0.05 GLN 1833

ILE 1543 0.28 MET 1914 -0.05 GLN 1833

ILE 1543 0.34 THR 1915 -0.04 PRO 1691

ILE 1543 0.28 GLU 1916 -0.05 PRO 1691

ILE 1543 0.24 PHE 1917 -0.06 PRO 1691

ILE 1543 0.27 LYS 1918 -0.04 MET 1718

ILE 1543 0.27 ARG 1919 -0.05 PRO 1691

ILE 1543 0.21 GLY 1920 -0.07 PRO 1691

ASN 1494 0.17 LEU 1921 -0.05 MET 1718

TYR 1466 0.19 PRO 1922 -0.06 MET 1718

TYR 1466 0.21 LEU 1923 -0.08 ASP 1505

TYR 1466 0.22 PHE 1924 -0.13 VAL 1504

TYR 1466 0.25 PRO 1925 -0.18 VAL 1504

TYR 1466 0.29 LEU 1926 -0.34 VAL 1683

TYR 1466 0.28 VAL 1927 -0.42 LEU 1682

TYR 1466 0.30 LYS 1928 -0.57 SER 1680

TYR 1466 0.39 PRO 1929 -0.68 LEU 1682

PRO 1465 0.33 HIS 1930 -0.64 PRO 1679

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Between 2015 and 2025, it was hosted by US2B (Nantes).
Last modification: april 24th, 2026.

Should you encounter any unexpected behaviour, please let us know. elNémo has been relocated. **Some cleaning from time to time** Sorry for the inconvenience.

*** 6bf8_closed ***

CA distance fluctuations for 2609040146391662543

--- normal mode 7 ---

Should you encounter any unexpected behaviour,
please let us know.
elNémo has been relocated.
Some cleaning from time to time
Sorry for the inconvenience.

* 6bf8_closed *